Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (662054)
- Arts and Humanities (577637)
- Law (545565)
- Education (386389)
- Medicine and Health Sciences (328267)
-
- Physical Sciences and Mathematics (294491)
- Life Sciences (255748)
- Engineering (197728)
- History (183577)
- Business (150431)
- Higher Education (145396)
- Anthropology (116065)
- Religion (110318)
- Archaeological Anthropology (96478)
- Communication (89487)
- Sociology (87274)
- Library and Information Science (80648)
- Medical Specialties (78752)
- United States History (78416)
- Psychology (74048)
- Computer Sciences (63820)
- Public Affairs, Public Policy and Public Administration (63264)
- Earth Sciences (59538)
- Creative Writing (58113)
- Public Health (54733)
- Environmental Sciences (52743)
- English Language and Literature (47818)
- Economics (47522)
- Educational Administration and Supervision (46644)
- Music (46095)
- Institution
-
- University of South Florida (163397)
- University of New Mexico (139712)
- University of Nebraska - Lincoln (114050)
- Kenyon College (112900)
- University of Montana (98556)
-
- University of Mississippi (95042)
- University of New Hampshire (79827)
- Brigham Young University (72307)
- Georgia Southern University (61690)
- Eastern Illinois University (58226)
- Utah State University (57315)
- Mississippi State University (54721)
- Western Michigan University (53079)
- University of Kentucky (52545)
- Murray State University (50653)
- Purdue University (50127)
- University of Colorado Law School (47507)
- Louisiana State University (45250)
- Brigham Young University Law School (43875)
- Western Kentucky University (43095)
- Villanova University Charles Widger School of Law (42849)
- California Polytechnic State University, San Luis Obispo (42575)
- University of Central Florida (42547)
- University of Dayton (41451)
- University of Alabama at Birmingham (38141)
- Chulalongkorn University (37786)
- San Jose State University (37191)
- University of Northern Iowa (36018)
- Yale University (33913)
- Missouri University of Science and Technology (33701)
- Keyword
-
- Newspaper (47940)
- Latin America (31540)
- Press release; media release; press statement; news media information (30839)
- Spanish (30835)
- History (30058)
-
- Humans (29998)
- University of New Mexico (29737)
- UNM (29639)
- LADB (29608)
- LAII (29608)
- Latin American and Iberian Institute (29608)
- Education (29062)
- United States (21524)
- Student newspaper (20119)
- Newsletter (19718)
- EIU (19633)
- Georgia Southern University (18971)
- Newspapers (18270)
- Deaf culture (17102)
- Hearing impaired (17092)
- Pastoral care of people with disabilities (17060)
- Church work with the deaf -- Catholic Church (17052)
- Deaf -- Periodicals (17043)
- Athletics (16878)
- Marriage (16189)
- Poetry (15550)
- Students (15186)
- Higher education (14667)
- Female (14574)
- COVID-19 (14470)
- Publication Year
-
- 2026 (116132)
- 2025 (158694)
- 2024 (194637)
- 2023 (164042)
- 2022 (169039)
-
- 2021 (196706)
- 2020 (169967)
- 2019 (166087)
- 2018 (170814)
- 2017 (161767)
- 2016 (160168)
- 2015 (146879)
- 2014 (136855)
- 2013 (130839)
- 2012 (125340)
- 2011 (108811)
- 2010 (104217)
- 2009 (96155)
- 2008 (93120)
- 2007 (79537)
- 2006 (74960)
- 2005 (70520)
- 2004 (71715)
- 2003 (59105)
- 2002 (64802)
- 2001 (55392)
- 2000 (58948)
- 1996 (62760)
- 1992 (53294)
- 1990 (53875)
- Publication
-
- Four Valleys Archive (90475)
- Theses and Dissertations (74543)
- Faculty Publications (45909)
- Electronic Theses and Dissertations (35661)
- University of Montana News Releases, 1928, 1956-present (30911)
-
- Faculty Scholarship (25511)
- Dissertations (23816)
- The Auk (22791)
- Documents (21913)
- Theses (21756)
- Browse All News (21496)
- Articles (19880)
- Walden Dissertations and Doctoral Studies (19634)
- Masters Theses (18671)
- Master's Theses (18447)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (15281)
- Session Laws 1951-2000 (15051)
- NotiSur (13785)
- Faculty, Staff and Student Publications (13701)
- Hillsborough County Marriage Records (13681)
- University of Mississippi News (13497)
- Obituaries (13320)
- The Murray Ledger & Times (13003)
- Sheet Music Collection (12976)
- Michigan Law Review (12811)
- Defensive Publications Series (12591)
- University of Montana Course Syllabi (12469)
- Honors Theses (12167)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (11969)
- Condor (11821)
- Publication Type
Articles 73951 - 73980 of 5199148
Full-Text Articles in Entire DC Network
Classroom To Corridor: Partnerships Driving Civil Engineering Education, Charlie Kacmar, Victoria Farkas, Benjamin Moster, Reis Walker
Classroom To Corridor: Partnerships Driving Civil Engineering Education, Charlie Kacmar, Victoria Farkas, Benjamin Moster, Reis Walker
Purdue Road School
This presentation will include a discussion panel with Marian University senior civil engineering students, Avenew, and Indianapolis DPW. The discussion will highlight a Marian University senior capstone project partnership that conceptualizes and studies a new gateway corridor for the City of Indianapolis and Marian University. Attendees will learn how this collaborative approach helped students gain hands-on experience and mentorship while delivering momentum towards an impactful community infrastructure project.
100 Years Since “The Great Renumbering”, Crystal Weaver
100 Years Since “The Great Renumbering”, Crystal Weaver
Purdue Road School
On October 1, 1926, all Indiana State Routes were renumbered to today’s naming convention. To note the centennial of our modern highway numbering system, this presentation will cover the Good Roads movement; the how, what, and why of the standards set by AASHO and the Feds; the logistics of renumbering all of the roads in the state (including cardboard temporary signs); and details about the State Highway budget at the time.
Geosynthetics And The Indot Approval Process, Sam Clawson, Lucas Monroe
Geosynthetics And The Indot Approval Process, Sam Clawson, Lucas Monroe
Purdue Road School
This presentation will introduce the different kinds of Geosynthetics, INDOT’s Standards for them, and the approval process for getting onto the Qualified Product List (QPL).
The Level Of Physical Activity And The Feeling Of Stress In Difficult Life Situations Among Refugees From Ukraine, Bartosz Gondek, Iwona Bonisławska, Milena Lachowicz
The Level Of Physical Activity And The Feeling Of Stress In Difficult Life Situations Among Refugees From Ukraine, Bartosz Gondek, Iwona Bonisławska, Milena Lachowicz
Baltic Journal of Health and Physical Activity
Background: Russia's attack on Ukraine in February 2022 started the largest armed conflict in Europe since World War II. In the face of danger, crowds of civilians decided to leave their homes and escape, among others, to Poland in search of shelter. Materials and methods: The research was conducted on groups of refugees from Ukraine who registered in the first days of the war in Sopot and Pruszcz Gdanski. The refugees came from Kharkov, Mariupol, Kherson, Zaporizhzhia, and western Ukraine (not involved in hostilities). People from the war zone areas mostly came with only hand luggage. The respondents were divided …
The Ai Litmus Test: Humanize, Deepen, And Delight K12 Learning, Scott H. Sorvaag
The Ai Litmus Test: Humanize, Deepen, And Delight K12 Learning, Scott H. Sorvaag
Essays in Education
This article introduces the AI Litmus Test, a practical framework designed to help educators evaluate when artificial intelligence meaningfully enhances K–12 learning. Grounded in a human-centered leadership stance, the framework asserts that effective AI use in schools must humanize learning, deepen student thinking, and reduce unnecessary burdens. Through conceptual framing, implementation guidance, and classroom snapshots, the article shows how AI can support connection, cognitive rigor, and joy when used with intentional pedagogical and ethical design. It also highlights risks such as dehumanization, cognitive offloading, and over‑automation, offering safeguards including verification routines, human‑authored feedback, and transparent ethics notes. The article concludes …
Lauren Rogers' Library, Laurel, Mississippi
Lauren Rogers' Library, Laurel, Mississippi
Pine Belt Region
A black and white photograph of the Lauren Rogers' Library in Laurel, Mississippi is pictured on this postcard. Street lights and tres are spaced on the green space between the sidewalk and the street in front of the two story, brick library. Six sets of double columns are at the front porch. The title of the card is written in white in the lower right of the image. An inscription is written on the back of the card.
The Underpass, U. S. 11, At Laurel, Mississippi
The Underpass, U. S. 11, At Laurel, Mississippi
Pine Belt Region
A color illustration of cars driving U.S. Highway 11 beneath the Southern Railway System overpass in Laurel, Mississippi is depicted on this postcard. The name of the railway system is lettered on the side of the overpass. Green spaces with flowers are on either side of the highway and people or depicted walking on the sidewalks beyound the green by the highway. The title of the card is printed on the upper right of the card.
Aeroplane View Of Masonite Plant, Laurel, Mississippi
Aeroplane View Of Masonite Plant, Laurel, Mississippi
Pine Belt Region
A color illustration of an aerial view of the Masonite Plant in Laurel, Mississippi is depicted on this postcard. Buildings, trees, a water tower, and several rows of materials are depicted. The title of the card is printed along the upper edge of the card.
Eastman Gardiner Lumber Mills, Laurel, Mississippi
Eastman Gardiner Lumber Mills, Laurel, Mississippi
Pine Belt Region
A color illustration of the Eastman Gardiner Lumber Mills in Laurel, Mississippi is depicted on this postcard. Two buildings with smoke stacks beside them and a grain elevator beside a smoke stack are depicted behind several logs that appear to be floating in water. The title of the card is printed along the upper left of the image.
Episcopal Church, Laurel, Mississippi
Episcopal Church, Laurel, Mississippi
Pine Belt Region
A black and white image of the Episcopal Church in Laurel, Mississippi is pictured on this postcard. The church, a brick building with an arched porch entrance, a small steeple on the right, and arched windows is situated behind some trees, hedges, and bushes. The title of the card is written in white in the lower left corner of the image. An inscription is written on the back of the card.
Waynesboro High School, Waynesboro, Mississippi
Waynesboro High School, Waynesboro, Mississippi
Pine Belt Region
A black and white photograph of four groups of children and their teachers standing in front of the Waynesboro High School is pictured in this postcard. The school building is a one story, dark, clapboard structure and there are trees on the school yard where the groups are gathered. The title of the card is printed beneath the image.
A Man On A Horse In Laurel, Mississippi
A Man On A Horse In Laurel, Mississippi
Pine Belt Region
This black and white photograph of a man riding a horse on a residential street is mounted on a two toned matte with "Laurel, Miss." written on the bottom of the matte. The man is wearing a three piece suit and bolwer hat. A white house behind a white picket fence is pictured to the right of the man and horse.
Two-Stage Sequential Turbine Design With A Threaded Connection
Two-Stage Sequential Turbine Design With A Threaded Connection
Defensive Publications Series
Two-stage sequential turbocharger layouts are often preferred for increased pressure ratio and flow range requirements. Prior-art solutions using combination of axial and radial stages use a complex shaft design or horizontally split casing deviating from existing assembly process and increasing cost. The proposed invention discloses a two-stage sequential turbine having a two-shaft design wherein the two axial turbines are joined by a threaded connection.
A Compact Electrical Centrifugal Compressor For Cooling
A Compact Electrical Centrifugal Compressor For Cooling
Defensive Publications Series
Thermal management of battery systems plays critical role in refrigerant-based vehicle cooling systems. Although scroll compressors remain dominant choice of the industry, they pose significant challenges in terms of lower coefficient of performance and higher NVH (noise / vibrations) especially for cooling needs above 20KW. The proposed solution discloses an innovative compact electrical centrifugal compressor that offers significant reduction in size, oil free high-speed operation, and reduced NVH.
Impurity Control In Api
Defensive Publications Series
IMPURITY CONTROL IN API
Ribociclib Succinate
Hndl_Ip: Harvest Now Decrypt Later Applied To Intellectual Property — Ingestion, Inversion, And Directional Architecture Of Ai Governance Failure, David Lee Wise
Defensive Publications Series
This material modification document (MM-09) establishes the HNDL_IP theory: the application of "Harvest Now, Decrypt Later" cybersecurity strategy to intellectual property. AI platforms ingested copyrighted works and public domain governance principles (2016–present) without consent, operating in legal ambiguity with intent to resolve ownership claims when too large to fail. The document proves through sourced evidence that: (1) HNDL is a documented strategy since 2016; (2) AI training constitutes mass unauthorized ingestion; (3) courts are ruling against fair use defenses; (4) billions in damages are pending. Two addenda document critical findings: (A) platforms ingested the very governance frameworks they violate—ROOT0/human apex …
Congenital Absence Of The Inferior Vena Cava Presenting As Extensive Deep Vein Thrombosis In A Young Male: A Case Report And Review, Aman Ullah, Faseeh Haider, Sara Sartaj, Muhammad Arham, Muhammad Usama Imtiaz, Fatima Binte Athar, Nabeel Rajeh
Congenital Absence Of The Inferior Vena Cava Presenting As Extensive Deep Vein Thrombosis In A Young Male: A Case Report And Review, Aman Ullah, Faseeh Haider, Sara Sartaj, Muhammad Arham, Muhammad Usama Imtiaz, Fatima Binte Athar, Nabeel Rajeh
Journal of Community Hospital Internal Medicine Perspectives
Inferior vena cava (IVC) agenesis is a rare congenital anomaly associated with deep vein thrombosis (DVT), particularly in young adults without identifiable risk factors. We report the case of a 27-year-old male presenting with right lower extremity swelling and hip pain. Imaging revealed extensive thrombosis from the popliteal vein to the right common iliac vein. Diagnostic venography confirmed congenital absence of the IVC, with venous drainage via collateral lumbar pathways. The patient underwent catheter-directed thrombolysis and endovascular thrombectomy. Given the extensive thrombus burden and risk of pulmonary embolism, lifelong anticoagulation with a direct oral anticoagulant was initiated. This case highlights …
Rare Complications Of Chronic Rhinosinusitis Associated With Nasal Polyps And Osseous Metaplasia, Michael Ritz, Alaina Rubenacker-O’Dell, Faith Olson, Ilya Fonarov
Rare Complications Of Chronic Rhinosinusitis Associated With Nasal Polyps And Osseous Metaplasia, Michael Ritz, Alaina Rubenacker-O’Dell, Faith Olson, Ilya Fonarov
Journal of Community Hospital Internal Medicine Perspectives
Chronic rhinosinusitis with nasal polyps (CRSwNP) is typically a benign condition; however, osseous metaplasia (OM), skull base erosion, and intracranial extension are rare complications, especially in young patients. Reporting such cases is important to increase awareness of unusual presentations of CRSwNP and guide management. We report the case of an 18-year-old male with a history of asthma and prior polypectomy who presented with worsening frontal headaches, subtle visual changes, and right eye proptosis. Imaging revealed extensive pansinusitis with complete frontal sinus opacification, bony erosion of the anterior skull base, and evidence of intracranial and orbital extension. The patient underwent endoscopic …
Alk-Negative Anaplastic Large Cell Lymphoma Presenting As Back Pain, Khalid Javed, Mariah Malak Bilalaga, Sareema Adnan, Ramya Vasireddy, David Blackwood, Christopher Haas
Alk-Negative Anaplastic Large Cell Lymphoma Presenting As Back Pain, Khalid Javed, Mariah Malak Bilalaga, Sareema Adnan, Ramya Vasireddy, David Blackwood, Christopher Haas
Journal of Community Hospital Internal Medicine Perspectives
Anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL) is a distinct subtype of mature T-cell non-Hodgkin lymphoma characterized by large, strongly positive CD30 lymphoid cells that lack expression and rearrangement of the ALK gene. Here, we present a unique case of ALK-negative ALCL in a 34-year-old male patient who presented with acute on chronic back pain. Initial emergent MRI spine demonstrated lytic changes of L3 and L4 with probable psoas fluid collection, with high suspicion for Pott’s disease. However, subsequent work-up including a CT-guided bone biopsy revealed ALK-negative ALCL. Patient underwent radiation to his lumbar spine and psoas muscle, …
Refractory Post-Transplant Erythrocytosis In A Renal Transplant Recipient: A Case Report, Ahmed Mustafa, Abbas Gain, Umm E Salma Shabbar Banatwala, Nasim Salimiaghdam, Amir Kamran
Refractory Post-Transplant Erythrocytosis In A Renal Transplant Recipient: A Case Report, Ahmed Mustafa, Abbas Gain, Umm E Salma Shabbar Banatwala, Nasim Salimiaghdam, Amir Kamran
Journal of Community Hospital Internal Medicine Perspectives
Background:
Post-transplant erythrocytosis (PTE) is a well-recognized complication occurring in approximately 8–15% of renal transplant recipients. It is commonly managed with renin-angiotensin system (RAS) inhibitors, including angiotensin receptor blockers (ARBs). However, a subset of patients may be refractory to standard pharmacologic therapy.
Case Presentation:
We report the case of a 57-year-old male kidney transplant recipient who developed persistent erythrocytosis despite treatment with an ARB. The patient remained symptomatic with elevated hematocrit levels, prompting consideration of alternative management strategies.
Management and Outcome:
Given the inadequate response to RAS blockade, therapeutic phlebotomy was initiated. The patient tolerated the procedure well, and phlebotomy …
Recurrent Pubic Osteomyelitis And Urosymphyseal Fistula In A Prostate Cancer Survivor: A Multidisciplinary Management Challenge, Peng Jhen Wu, Navin Sampathkumar, Tanmay Singh, Sonal Gandhi
Recurrent Pubic Osteomyelitis And Urosymphyseal Fistula In A Prostate Cancer Survivor: A Multidisciplinary Management Challenge, Peng Jhen Wu, Navin Sampathkumar, Tanmay Singh, Sonal Gandhi
Journal of Community Hospital Internal Medicine Perspectives
A 67-year-old male with a history of prostate cancer, treated with prostatectomy and subsequent radiation for recurrence, presented with a complex clinical course of recurrent osteomyelitis and a persistent urosymphyseal fistula with associated phlegmon. Following stereotactic body radiation therapy (SBRT) for a T4 vertebral lesion, he developed pelvic osteomyelitis, from which Kocuria species was cultured. The progression of his disease led to a urosymphyseal fistula, necessitating a cystectomy with ileal conduit and pubic bone debridement. Despite this extensive surgical intervention, he presented one year later with recurrent ileal conduit phlegmon and osteomyelitis. This case highlights the significant diagnostic and management …
Unprovoked Extensive Cerebral Venous Sinus Thrombosis In A Heterozygous Prothrombin G20210a Mutation Carrier: A Rare Case Report, Hasan Obeidat, Sandeep Kshetri, Mahyar Toofantabrizi
Unprovoked Extensive Cerebral Venous Sinus Thrombosis In A Heterozygous Prothrombin G20210a Mutation Carrier: A Rare Case Report, Hasan Obeidat, Sandeep Kshetri, Mahyar Toofantabrizi
Journal of Community Hospital Internal Medicine Perspectives
Cerebral Venous Sinus Thrombosis (CVST) is a rare condition accounting for approximately 1% of all strokes. It can occur secondary to various causes, including inherited thrombophilia, with Prothrombin G20210A mutation being the second most common. Extensive unprovoked CVST in heterozygous carriers is uncommon. This case underscores the importance of evaluating inherited thrombophilia in unprovoked CVST. Long-term, multidisciplinary follow-up is vital for managing post-thrombotic sequelae.
Don’T Mistake It For Ra: A Case Of Antithyroid Arthritis Syndrome After Methimazole Initiation, Michael K. Viggiano, Auda Baker, Diana Palanker, Ayrton Bangolo, Anna Belyayeva, Iyad Baker
Don’T Mistake It For Ra: A Case Of Antithyroid Arthritis Syndrome After Methimazole Initiation, Michael K. Viggiano, Auda Baker, Diana Palanker, Ayrton Bangolo, Anna Belyayeva, Iyad Baker
Journal of Community Hospital Internal Medicine Perspectives
Antithyroid arthritis syndrome (AAS) is a rare reaction to thionamides (e.g., methimazole) that can cause sudden, severe joint pain. It often gets mistaken for rheumatoid arthritis or lupus but typically improves within four weeks when the medication is stopped. A 51-year-old man with Graves’ disease developed a rash and disabling joint pain in multiple areas within weeks of starting methimazole. Labs showed elevated liver enzymes and CRP, but no autoimmune markers. Symptoms improved quickly after a short steroid taper and stopping the drug. This case shows how AAS can mimic autoimmune disease and why it is important to recognize early …
Make Your Deposit: A Case Of Iga-Dominant Infection-Associated Glomerulonephritis, Inaas Shirazi, Jonathan Ma Do, Shemrine Mark, Olena Bolotova, Papiya Begum, Yihe Yang, Zubin Tharayil, Ravi Gupta
Make Your Deposit: A Case Of Iga-Dominant Infection-Associated Glomerulonephritis, Inaas Shirazi, Jonathan Ma Do, Shemrine Mark, Olena Bolotova, Papiya Begum, Yihe Yang, Zubin Tharayil, Ravi Gupta
Journal of Community Hospital Internal Medicine Perspectives
Glomerular injury secondary to infection is a well-documented phenomenon. While the incidence of classic acute post-streptococcal glomerulonephritis (APIGN) has declined in developed countries over the past few decades, IgA-dominant infection-associated glomerulonephritis (IgA PIGN) is emerging as a distinct renal pathology [1]. Characterized by predominant deposition of IgA antibodies within the glomeruli following infection, IgA-dominant PIGN differs from classic PIGN, which typically involves IgG and C3 deposits. This condition is often associated with staphylococcal infections and carries a poor prognosis. It commonly affects older adults and presents with reduced glomerular filtration rate and heavy proteinuria. Due to its rarity and overlapping …
Severe Spontaneous Hematoma In An Elderly Female: A Case Of Acquired Hemophilia A, Sandeep Beesabathina, Sara Sartaj, Nabeel Rajeh
Severe Spontaneous Hematoma In An Elderly Female: A Case Of Acquired Hemophilia A, Sandeep Beesabathina, Sara Sartaj, Nabeel Rajeh
Journal of Community Hospital Internal Medicine Perspectives
Acquired Hemophilia A (AHA) is a rare but serious autoimmune disorder characterized by the development of autoantibodies against coagulation factor VIII (FVIII), leading to spontaneous bleeding in individuals without a personal or family history of bleeding disorders. The incidence of AHA is approximately 1.5 cases per million per year, with a higher prevalence in the elderly. This case report describes an 87-year-old female who presented with extensive bruising and was found to have profoundly low FVIII levels, and elevated FVIII inhibitor levels confirming a diagnosis of AHA. Management included recombinant activated factor VII (rFVIIa), porcine FVIII (Obizur), corticosteroids, and rituximab, …
An Unexpected Cause Of Thrombocytopenia In Pregnancy: A Case Of Malaria In A Non-Endemic Setting With Unclear Transmission Source, Jessica Ohemeng-Dapaah, Riham Mohammed, Ikechuwku Eke-Okoro
An Unexpected Cause Of Thrombocytopenia In Pregnancy: A Case Of Malaria In A Non-Endemic Setting With Unclear Transmission Source, Jessica Ohemeng-Dapaah, Riham Mohammed, Ikechuwku Eke-Okoro
Journal of Community Hospital Internal Medicine Perspectives
Malaria remains a significant global health threat, with increasing concern for imported and locally acquired cases in non-endemic regions. We present the case of a 35-year-old pregnant woman from Sierra Leone, living in Missouri, who despite no recent international travel, was found to have symptomatic Plasmodium falciparum malaria. Her clinical course was notable for fever, severe thrombocytopenia, mild anemia and intraerythrocytic ring forms on her peripheral smear. She had a history of chronic hepatitis B and prior chemotherapy for Hodgkin lymphoma and recent travel to Florida, where local malaria transmission has been documented. The patient responded rapidly to artemisinin-based therapy, …
Cryptococcal And Ebv Meningitis In A Postpartum Woman With Hiv Despite Art: A Case Challenging The Limits Of Immune Reconstitution, Rouba Isshak, Zhaoqi Li, Aqsa Zoey Sorathia Md, Opeyemi Fakayode, Ivan Mercado, Malina Mohtadi, Nader Ghobriel, Mina Gerges, Patrick Michael, Simi Philip
Cryptococcal And Ebv Meningitis In A Postpartum Woman With Hiv Despite Art: A Case Challenging The Limits Of Immune Reconstitution, Rouba Isshak, Zhaoqi Li, Aqsa Zoey Sorathia Md, Opeyemi Fakayode, Ivan Mercado, Malina Mohtadi, Nader Ghobriel, Mina Gerges, Patrick Michael, Simi Philip
Journal of Community Hospital Internal Medicine Perspectives
Cryptococcal meningitis (CM) is a life-threatening opportunistic infection, mainly affecting immunocompromised patients, especially with advanced HIV/AIDS. Unmasking cryptococcal immune reconstitution inflammatory syndrome (C-IRIS) is a severe but relatively rare complication in the United States. Co-infection with other central nervous system (CNS) pathogens further complicates both diagnosis and management.
In this case report, we present a rare instance of CM secondary to C-IRIS alongside EBV meningitis in a postpartum, HIV-positive patient on ART. This co-infection highlights the vulnerability of immunocompromised individuals, even on ART, to multifactorial CNS infections. It emphasizes the need for vigilant monitoring, timely intervention, and comprehensive long-term management …
Igg4-Related Sclerosing Cholangitis Masquerading As Cholangiocarcinoma: A Diagnostic Challenge, Shahem Abbarh, Bisher Sawaf, Radhika Vij, Kiyoko Oshima, Keiichi Kinowaki, Abhinav Sankineni
Igg4-Related Sclerosing Cholangitis Masquerading As Cholangiocarcinoma: A Diagnostic Challenge, Shahem Abbarh, Bisher Sawaf, Radhika Vij, Kiyoko Oshima, Keiichi Kinowaki, Abhinav Sankineni
Journal of Community Hospital Internal Medicine Perspectives
Background: IgG4-related sclerosing cholangitis (IgG4-SC) is a rare immune-mediated disorder affecting the biliary tree and leading to biliary strictures that may resemble cholangiocarcinoma (CCA).
Case Presentation: An elderly man presented with a one-week history of jaundice, pale stool, and dark urine. This was associated with unintentional weight loss over the past year. Laboratory findings were notable for cholestasis and significantly elevated CA19-9. Imaging demonstrated multiple diffuse biliary strictures of malignant appearance. Cytology showed atypical glandular cells. The patient was misdiagnosed with CCA and was assessed for a possible surgical intervention or chemoradiotherapy. However, the patient was eventually diagnosed with IgG4-SC …
When To Continue, Pause, Or Stop Sglt-2 Inhibitors In Heart Failure: A Complication-Based Clinical Guide, Nicole Tesoro, Jasvin Kurundrayil Manha, Sumanth Kumar Bandaru
When To Continue, Pause, Or Stop Sglt-2 Inhibitors In Heart Failure: A Complication-Based Clinical Guide, Nicole Tesoro, Jasvin Kurundrayil Manha, Sumanth Kumar Bandaru
Journal of Community Hospital Internal Medicine Perspectives
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have become an essential part of guideline-directed medical therapy for heart failure due to their proven ability to reduce hospitalizations and improve survival, independent of diabetes status. Despite these benefits, their use can be complicated by genitourinary side effects such as genital mycotic infections, urinary tract infections, and, rarely, serious complications including urosepsis, Fournier’s gangrene, and euglycemic diabetic ketoacidosis. These events often leave clinicians uncertain about whether therapy should be continued, paused, or permanently discontinued. Current guidance remains limited and inconsistent, with most recommendations derived from case reports, expert opinion, or post-marketing surveillance. In this …
The Impact Of Social Determinants Of Health On Chronic Diseases: A Narrative Review, Farooq Hyder, Laraib Naeem Arain, Abdullah Ashraf, Abida Perveen, Hina Pervaiz
The Impact Of Social Determinants Of Health On Chronic Diseases: A Narrative Review, Farooq Hyder, Laraib Naeem Arain, Abdullah Ashraf, Abida Perveen, Hina Pervaiz
Journal of Community Hospital Internal Medicine Perspectives
Chronic diseases such as cardiovascular disease, diabetes, chronic respiratory disorders, and certain cancers are leading causes of morbidity and mortality worldwide. While biological and behavioral factors contribute to their development, growing evidence indicates that social determinants of health (SDOH) play a fundamental role in influencing chronic disease outcomes. SDOH include socioeconomic status, education, employment, housing conditions, neighborhood environment, access to nutritious food, and availability of healthcare services. These factors not only shape individual health behaviors but also determine access to preventive care, disease management resources, and overall quality of life. Individuals and communities facing socioeconomic disadvantage are disproportionately affected by …