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Artificial Intelligence In The Prosecution Of International Crimes, Marta Bo Feb 2026

Artificial Intelligence In The Prosecution Of International Crimes, Marta Bo

International Law Studies

International criminal prosecutions face growing evidentiary challenges due to the vast and heterogeneous digital material generated during conflicts, including user-generated videos, social media, and intercepted communications. This article examines the potential role of artificial intelligence (AI) in supporting investigations and trials before the International Criminal Court (ICC). Rather than replacing judicial decision-making, AI can assist with specific tasks, particularly in establishing contextual elements and linkage evidence central to international crimes. The article explores three main areas: AI-driven biometric tools for facial and speech recognition; AI techniques for detecting patterns of violence and mapping command structures; and applications during trial proceedings, …

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Stocks And Shocks: Assessing The Relative Roles Of Public And Private Inventories In Buffering Rice Price Volatility In The Philippines, Bernhard Dalheimer, Kenneth Foster, Gerald E. Shively, Valerien O. Pede, Dela-Dem Doe Fiankor, Jacob Ricker-Gilbert, Pratibha Bist Feb 2026

Stocks And Shocks: Assessing The Relative Roles Of Public And Private Inventories In Buffering Rice Price Volatility In The Philippines, Bernhard Dalheimer, Kenneth Foster, Gerald E. Shively, Valerien O. Pede, Dela-Dem Doe Fiankor, Jacob Ricker-Gilbert, Pratibha Bist

Department of Agricultural Economics Faculty Publications

Public stockholding of food is politically contentious and economically challenging. Although private stocks are generally understood to be more efficient than public stocks at providing a reliable buffer against production shortfalls, private stocks often fail to stabilize prices during extreme food market shocks. Moreover, maintaining large public stock programs in which the government acts as the buyer or seller of last resort, can be very costly. This paper analyzes the recent historical success of public and private rice stocks in stabilizing domestic rice prices in the Philippines, the world’s largest net importer of rice. Relying on competitive storage theory and …

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Primary Tumor Size And Tumor-Vessel Interface Following Capecitabine And Temozolomide For Pancreatic Neuroendocrine Tumor, Jin Guo, Kever A Lewis, Laura Prakash, Priya Bhosale, Ajaykumar Morani, Matthew H G Katz, Ching-Wei D Tzeng, Naruhiko Ikoma, Rebecca Snyder, Michael P Kim, Chandrikha Chandrasekharan, Arvind Dasari, James C Yao, Jeffrey E Lee, Jessica E Maxwell, Daniel M Halperin Feb 2026

Primary Tumor Size And Tumor-Vessel Interface Following Capecitabine And Temozolomide For Pancreatic Neuroendocrine Tumor, Jin Guo, Kever A Lewis, Laura Prakash, Priya Bhosale, Ajaykumar Morani, Matthew H G Katz, Ching-Wei D Tzeng, Naruhiko Ikoma, Rebecca Snyder, Michael P Kim, Chandrikha Chandrasekharan, Arvind Dasari, James C Yao, Jeffrey E Lee, Jessica E Maxwell, Daniel M Halperin

Faculty, Staff and Student Publications

Capecitabine/temozolomide (CAPTEM) is an established regimen for patients with metastatic pancreatic neuroendocrine tumors (PanNET) that is being increasingly used for tumor volume reduction in patients with borderline anatomically resectable disease. We sought to understand the response of the primary tumor, defined as changes in the tumor–vascular interface (TVI). This is a retrospective, single-institution study of patients with locally advanced or metastatic PanNET treated with CAPTEM between 2010 and 2020. RECISTv1.1 measurements and TVI assessments of the primary tumor were performed on pre- and post-therapy images. Patients with locally advanced or metastatic PanNET at presentation (n = 47) were included. …

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Tumor-Immune-Neural Circuit Disrupts Energy Homeostasis In Cancer Cachexia, Xiuhui Shi, Alex X Arreola, Zhijun Zhou, Jingxuan Yang, Mingyang Liu, Yang Cai, Yu Ren, Hao Yuan, Qun Chen, Xinjie Chen, Xinyu Yang, Yimei Meng, Jingyi Wang, Wenyi Luo, Michael C Rudolph, Rohan Varshney, Kar-Ming Fung, Chao Xu, Wei R Chen, Michael S Bronze, Lei Zheng, Yi-Ping Li, Courtney W Houchen, Yuqing Zhang, Min Li Feb 2026

Tumor-Immune-Neural Circuit Disrupts Energy Homeostasis In Cancer Cachexia, Xiuhui Shi, Alex X Arreola, Zhijun Zhou, Jingxuan Yang, Mingyang Liu, Yang Cai, Yu Ren, Hao Yuan, Qun Chen, Xinjie Chen, Xinyu Yang, Yimei Meng, Jingyi Wang, Wenyi Luo, Michael C Rudolph, Rohan Varshney, Kar-Ming Fung, Chao Xu, Wei R Chen, Michael S Bronze, Lei Zheng, Yi-Ping Li, Courtney W Houchen, Yuqing Zhang, Min Li

Faculty, Staff and Student Publications

Cancer-induced cachexia and anorexia are debilitating complications across many cancers, yet effective treatments remain limited due to a poor understanding of the underlying mechanisms. Here, we identify an uncharacterized tumor-immune-neural circuit driving these syndromes, centered on growth and differentiation factor 15 (GDF15). Using genetically engineered mouse models, we find that loss of GDF15 protects against appetite loss, muscle wasting, and fat loss in pancreatic, lung, and skin cancers. Single-cell RNA sequencing reveals macrophages as a major source of GDF15, induced by tumor-derived colony-stimulating factor 1 (CSF1). GDF15 acts via the central nervous system to enhance β-adrenergic signaling in the tumor …

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Weight Loss Patterns And Clinical Outcomes Of Glp1 Receptor Agonists In Breast Cancer Survivors, Jasmine S Sukumar, Akshara Singareeka Raghavendra, Sarah Pasyar, Roland L Bassett, Debu Tripathy, Carlos H Barcenas, Karen M Basen-Engquist, Banu K Arun Feb 2026

Weight Loss Patterns And Clinical Outcomes Of Glp1 Receptor Agonists In Breast Cancer Survivors, Jasmine S Sukumar, Akshara Singareeka Raghavendra, Sarah Pasyar, Roland L Bassett, Debu Tripathy, Carlos H Barcenas, Karen M Basen-Engquist, Banu K Arun

Faculty, Staff and Student Publications

Use of glucagon-like peptide-1 receptor agonists (GLP1-RA) for weight loss is increasing; implications in breast cancer (BC) survivors remain unclear.This retrospective cohort study evaluated treatment patterns, weight loss, and outcomes in BC survivors at an academic institution receiving GLP1-RA. We evaluated patients with non-metastatic (ductal carcinoma in situ (DCIS), stage 1-3) BC who received GLP1-RA (2005 - 2024). Linear regression models estimated associations between weight change and clinical factors. After excluding DCIS, propensity score matching (1:2) was used to match patients who received GLP1-RA with patients who did not, based on confounding covariates. Kaplan-Meier estimates and log-rank tests compared disease-free …

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Targeting Oxalate Production By Combining Enzyme Inhibition And Proteolysis Activation: A Novel Therapeutic Approach For Primary Hyperoxaluria Type 1, Fabio Arias, Sumati Rohilla, Yudibeth Sixto-López, Koral S E Richard, Sandeep Das, Sumit K Anand, Pilar Maria Luque-Navarro, Guillermo Bañuelos-Sanchez, Juan Luis Pacheco-García, Reethika Gade, M Peyton Mckinney, Dhananjay Kumar, Jemiah Maxie, W Rylan Corr, Nilesh Pandey, Harpreet Kaur, Jibin Ding, Lin Tan, Elisha Scott, Hyung Nam, Eyal Gottlieb, A Wayne Orr, Nirav Dhanesha, Arif Yurdagul, Angel L Pey, Francisco Franco-Montalbán, José A Gómez Vidal, Oren Rom, Mónica Díaz-Gavilán Feb 2026

Targeting Oxalate Production By Combining Enzyme Inhibition And Proteolysis Activation: A Novel Therapeutic Approach For Primary Hyperoxaluria Type 1, Fabio Arias, Sumati Rohilla, Yudibeth Sixto-López, Koral S E Richard, Sandeep Das, Sumit K Anand, Pilar Maria Luque-Navarro, Guillermo Bañuelos-Sanchez, Juan Luis Pacheco-García, Reethika Gade, M Peyton Mckinney, Dhananjay Kumar, Jemiah Maxie, W Rylan Corr, Nilesh Pandey, Harpreet Kaur, Jibin Ding, Lin Tan, Elisha Scott, Hyung Nam, Eyal Gottlieb, A Wayne Orr, Nirav Dhanesha, Arif Yurdagul, Angel L Pey, Francisco Franco-Montalbán, José A Gómez Vidal, Oren Rom, Mónica Díaz-Gavilán

Faculty, Staff and Student Publications

Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder caused by hepatic oxalate overproduction due to alanine-glyoxylate aminotransferase (AGXT) deficiency. Therapeutic strategies targeting glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), key enzymes in glyoxylate metabolism, have shown promise in reducing oxalate burden. However, recently approved siRNA therapies remain limited by high cost, unfavorable pharmacokinetics, and limited global accessibility. We report the development of compound 2, a dual GO/LDHA inhibitor (K i = 390 and 40 nM, respectively) that also promotes hydrophobic tag-mediated autophagic degradation of LDHA. Its efficacy was evaluated in Agxt –/– mice, both in primary …

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Shawn Williams V. Robin Nyberg Feb 2026

Shawn Williams V. Robin Nyberg

2026 Decisions

USDC for the Western District of Pennsylvania

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Serial False Lumen Patency Evaluation Of A Type B Dissection Represented With Malperfusion Following Medical Management, S Taha Zaidi, Quang Le, Firas Mussa, Akiko Tanaka, S Keisin Wang, Arash Keyhani, Kourosh Keyhani Feb 2026

Serial False Lumen Patency Evaluation Of A Type B Dissection Represented With Malperfusion Following Medical Management, S Taha Zaidi, Quang Le, Firas Mussa, Akiko Tanaka, S Keisin Wang, Arash Keyhani, Kourosh Keyhani

Faculty, Staff and Student Publications

False lumen evolution in type B aortic dissection, particularly with medical management and anticoagulation, remains incompletely understood. We report a 55-year-old man on apixaban for pulmonary embolism with a subacute zone 3-10L TBAD without malperfusion. He was managed medically initially and represented twice over 2 months with back pain and acute right lower extremity ischemia. Serial imaging demonstrated dynamic remodeling with progression from partial to near-complete thrombosis to full reperfusion with true lumen compression. Urgent endovascular repair was performed successfully. This case illustrates the unpredictable course of medically managed TBAD and need for judicious use of anticoagulation.

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Geometry Of Neural Dynamics Along The Cortical Attractor Landscape Reflects Changes In Attention, Hayoung Song, Ruiqi Chen, Thomas L Botch, Todd S Braver, Monica D Rosenberg, Jeffrey M Zacks, Shinung Ching Feb 2026

Geometry Of Neural Dynamics Along The Cortical Attractor Landscape Reflects Changes In Attention, Hayoung Song, Ruiqi Chen, Thomas L Botch, Todd S Braver, Monica D Rosenberg, Jeffrey M Zacks, Shinung Ching

2020-Current year OA Pubs

Large-scale brain activity reflects changes in attention. To understand how, we tested a hypothesis that the geometry of neural dynamics on the cortical attractor landscape, or movement along its "hills and valleys", reflects attentional states. A dynamical systems model separating intrinsic dynamics from stimulus-driven influences was fit to fMRI data collected during rest, tasks, and movie-watching. Model simulations revealed a set of attractors aligned with canonical functional brain networks. The speed and direction of neural trajectories toward these attractors varied systematically with attentional states over time and across contexts. When participants were paying attention to effortful tasks, neural dynamics converged …

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February 12, 2026, The Daily Mississippian Feb 2026

February 12, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

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Menopause 101, Stephanie Carlson, Emma Parkhurst, Ashley Yaugher, Cris Meier Feb 2026

Menopause 101, Stephanie Carlson, Emma Parkhurst, Ashley Yaugher, Cris Meier

All Current Publications

This fact sheet provides women with basic information about perimenopause, menopause, and postmenopause, along with helpful tips and resources to better prepare for or manage these phases of life.

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Systematic Synthesis Of Crispr/Cas Applications For Enhancing Salt Tolerance In Crops: A Decade Of Progress And Challenges, Xindi Sun, Fusheng Wu, Zhuanzhuan Ma, Guohao Liang, Shumei Chen, Xutong Hu, Shugao Fan, Ying Zhao Feb 2026

Systematic Synthesis Of Crispr/Cas Applications For Enhancing Salt Tolerance In Crops: A Decade Of Progress And Challenges, Xindi Sun, Fusheng Wu, Zhuanzhuan Ma, Guohao Liang, Shumei Chen, Xutong Hu, Shugao Fan, Ying Zhao

School of Mathematical & Statistical Sciences Faculty Publications

Soil salinity is a major constraint on global crop productivity, driving the need for salt-tolerant varieties. While CRISPR-Cas genome editing offers targeted solutions for trait improvement, significant biological and technical bottlenecks limit its application in conferring salt stress resilience. This systematic summarizes findings from 83 peer-reviewed studies (2015–2024) employing CRISPR/Cas technologies to improve salt tolerance in five major crops (rice, wheat, maize, sorghum, barley). Our systematic review reveals that early single-gene edits achieved modest gains (30–50% Na⁺ exclusion) but often showed limited yield gains in field settings, potentially due to compensatory regulation and environmental variation. The literature suggests that multiplex …

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Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte Feb 2026

Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte

Faculty Publications

Therapeutic proteins face a critical pharmacokinetic challenge: rapid clearance from circulation limits their clinical efficacy. Albumin-binding domains (ABDs) offer an elegant solution by enabling therapeutic proteins to “hitchhike” on serum albumin’s favorable 19-day half-life through FcRn-mediated recycling. Clinical validation through approved therapeutics like ozoralizumab demonstrates the success of this approach, with preclinical studies showing fusion to an ABD extended half-life to 18 days. This review provides an analysis of ABD-fusion protein design, integrating structural biology, computational prediction, and rational engineering principles. We catalog the major classes of albumin-binding modalities, including bacterial three-helix bundle domains, engineered peptides, antibody-derived binders, and alternative …

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Teaching Peace, Stopping Bullying: The Transformative Power Of Kh Ahmad Dahlan’S Psychoeducation, Wahyu Nanda Eka Saputra, Anya Ahda Mahira, Salsa Puspita Dwi Djajuli Feb 2026

Teaching Peace, Stopping Bullying: The Transformative Power Of Kh Ahmad Dahlan’S Psychoeducation, Wahyu Nanda Eka Saputra, Anya Ahda Mahira, Salsa Puspita Dwi Djajuli

Buletin Konseling Inovatif

Bullying in schools remains a serious problem that negatively impacts students' academic and psychological development. A safe and violence-free learning environment is crucial to supporting the achievement of national education goals, thus requiring effective interventions to reduce bullying behavior. This study aims to test the effectiveness of group counseling services using psychoeducational techniques based on the teachings of KH. Ahmad Dahlan in reducing bullying behavior. The scope of the study focuses on the application of peaceful values in junior high schools as a prevention strategy and as a positive character development strategy for students. This study used a quantitative approach …

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The Efficacy Of Rapid Counseling With Single-Session Music Therapy On Enhancing Emotion Regulation In Response To Activating Events, Aloysius Selo Aryobimo Oentarto Feb 2026

The Efficacy Of Rapid Counseling With Single-Session Music Therapy On Enhancing Emotion Regulation In Response To Activating Events, Aloysius Selo Aryobimo Oentarto

Buletin Konseling Inovatif

This study examines the efficacy of Rapid Counseling with Single-Session Music Therapy (RCSSMT) in enhancing emotion regulation in response to activating events. Many daily circumstances are uncontrollable, often leading individuals with negative thought patterns to experience distress and anxiety, known as activating events. Music therapy, as a holistic approach, acts as an emotion-focused coping strategy by calming physiological stress responses and preparing the individual for cognitive restructuring. This research employed a single-subject pre-test, post-test, and follow-up design, with the subject being SG, who had the lowest initial score on the Emotion Regulation Questionnaire. The scores showed a gradual but significant …

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Keeping It Real: Thoughts About The Art, Craft, And Business Of Writing Creative Nonfiction, Karen Rosica, Meredith Hall Feb 2026

Keeping It Real: Thoughts About The Art, Craft, And Business Of Writing Creative Nonfiction, Karen Rosica, Meredith Hall

Creative Nonfiction Magazine

No abstract provided.

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See The Difference, Sue William Silverman Feb 2026

See The Difference, Sue William Silverman

Creative Nonfiction Magazine

No abstract provided.

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In Praise Of Osmosis, Jill Drumm Feb 2026

In Praise Of Osmosis, Jill Drumm

Creative Nonfiction Magazine

No abstract provided.

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Foreign Bodies, Grace Talusan Feb 2026

Foreign Bodies, Grace Talusan

Creative Nonfiction Magazine

No abstract provided.

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You Have The Right To Remain Silent, Pamela Skjolsvik Feb 2026

You Have The Right To Remain Silent, Pamela Skjolsvik

Creative Nonfiction Magazine

No abstract provided.

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Saving My Breath, Tamara Dean Feb 2026

Saving My Breath, Tamara Dean

Creative Nonfiction Magazine

No abstract provided.

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Watching My Mother Hallucinate, Diana Hume George Feb 2026

Watching My Mother Hallucinate, Diana Hume George

Creative Nonfiction Magazine

No abstract provided.

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Non Pro Nobis, John Bess Feb 2026

Non Pro Nobis, John Bess

Creative Nonfiction Magazine

No abstract provided.

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Missing, Merilee D. Karr Feb 2026

Missing, Merilee D. Karr

Creative Nonfiction Magazine

No abstract provided.

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Mrs. Kelly, Paul Austin Feb 2026

Mrs. Kelly, Paul Austin

Creative Nonfiction Magazine

No abstract provided.

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Introduction, Abraham Verghese Feb 2026

Introduction, Abraham Verghese

Creative Nonfiction Magazine

No abstract provided.

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The Good Doctor, Helena Studer Feb 2026

The Good Doctor, Helena Studer

Creative Nonfiction Magazine

No abstract provided.

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Silence Kills: Speaking Out And Saving Lives, Lee Gutkind Feb 2026

Silence Kills: Speaking Out And Saving Lives, Lee Gutkind

Creative Nonfiction Magazine

No abstract provided.

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Foreword: Toward A More Caring, And Curing, Health System, Karen Wolk Feinstein Feb 2026

Foreword: Toward A More Caring, And Curing, Health System, Karen Wolk Feinstein

Creative Nonfiction Magazine

No abstract provided.

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Front Matter Feb 2026

Front Matter

Creative Nonfiction Magazine

No abstract provided.

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