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Articles 698881 - 698910 of 5149677
Full-Text Articles in Entire DC Network
Beyond Accuracy In Machine Learning., Aneseh Alvanpour
Beyond Accuracy In Machine Learning., Aneseh Alvanpour
Electronic Theses and Dissertations
Machine Learning (ML) algorithms are widely used in our daily lives. The need to increase the accuracy of ML models has led to building increasingly powerful and complex algorithms known as black-box models which do not provide any explanations about the reasons behind their output. On the other hand, there are white-box ML models which are inherently interpretable while having lower accuracy compared to black-box models. To have a productive and practical algorithmic decision system, precise predictions may not be sufficient. The system may need to have transparency and be able to provide explanations, especially in applications with safety-critical contexts …
The Role Of Organizational Culture And Relationship Marketing In Disability Sport Sponsorship: An Exemplar Case Study., Nina Siegfried
The Role Of Organizational Culture And Relationship Marketing In Disability Sport Sponsorship: An Exemplar Case Study., Nina Siegfried
Electronic Theses and Dissertations
Worldwide, disability sport faces funding challenges. Sponsorship offers a viable alternative to combat the lack of sustainable funding in disability sport. Exploring how organizational culture can be leveraged to increase strategic partnerships, the purposes of this multiple manuscript dissertation were to (a) examine the elements of the organizational culture that make a successful international wheelchair basketball sport club attractive to external partners and (b) determine what role those organizational cultural elements play in leveraging relationship marketing (RM) for sponsorship acquisition and retention. Utilizing an exemplar case study methodology, the focus of this study was the RSV Lahn-Dill, an international wheelchair …
Adipose-Derived Stromal Vascular Fraction Therapy Improves Age-Related Adrenergic Mediated Microvascular Dysfunction And Increases Revascularization Potential Following Injury., Gabrielle Brown
Electronic Theses and Dissertations
The role of the microcirculation is to balance blood flow and oxygen delivery to meet local metabolic and oxygen demands. With advancing age, the health of the endothelium declines leading to improper augmentation of the microcirculation; decreasing vasoreactivity and angiogenic potential which can further increase the risk of ischemia. The multiple contributing factors that drive the decline in endothelial health with age make traditional pharmacological interventions challenging whereas cell-based therapies can exert multifactorial gains. Adipose-derived stromal vascular fraction (SVF) is an emerging therapeutic for its easily accessible, autologous, anti-inflammatory, and angiogenic properties. It is a heterogenous population comprised of leukocyte …
Spectroscopic Measurements Of Meibum Compositional, Structural, And Functional Relationships To Elucidate The Role Of Meibum In Dry Eye., Anthony Chigozie Ewurum
Spectroscopic Measurements Of Meibum Compositional, Structural, And Functional Relationships To Elucidate The Role Of Meibum In Dry Eye., Anthony Chigozie Ewurum
Electronic Theses and Dissertations
The major aim of my dissertation was to investigate the etiology of dry eye disease which affects about 7 million people in the United States, causing symptoms that can lead to visual disturbance. Correlation between dry eye and an abnormal lipid layer of the tear film has been found. Tear film lipids originate mostly from the meibomian glands. Cholesteryl ester (CE) and Wax ester (WE) lipids make up most of the human meibum lipidome and the CE/WE ratio has been shown to decrease in patients with meibomian gland dysfunction. Model studies using synthetic CE and WE, although providing some insight, …
Machine Learning Approaches For Early Prediction Of Hypertension., Heba Elsayed Mohamed Kandil
Machine Learning Approaches For Early Prediction Of Hypertension., Heba Elsayed Mohamed Kandil
Electronic Theses and Dissertations
Hypertension afflicts one in every three adults and is a leading cause of mortality in 516, 955 patients in USA. The chronic elevation of cerebral perfusion pressure (CPP) changes the cerebrovasculature of the brain and disrupts its vasoregulation mechanisms. Reported correlations between changes in smaller cerebrovascular vessels and hypertension may be used to diagnose hypertension in its early stages, 10-15 years before the appearance of symptoms such as cognitive impairment and memory loss. Specifically, recent studies hypothesized that changes in the cerebrovasculature and CPP precede the systemic elevation of blood pressure. Currently, sphygmomanometers are used to measure repeated brachial artery …
Factors Influencing American Indian Adolescents' Abstention And Desistance From Drug Usage., Ruben Olegovich Pavlov
Factors Influencing American Indian Adolescents' Abstention And Desistance From Drug Usage., Ruben Olegovich Pavlov
Electronic Theses and Dissertations
Informed by Hirschi’s (1969) social bond theory and by Gottfredson and Hirschi’s (1990) general theory of crime (GTC), the proposed study intends to identify the factors more likely to differentiate drug-use desisters (i.e., adolescents who reported life-time usage, but did not report recent drug use) from those who never used drugs and from those who reported continuous use of drugs. The study is based on a quantitative analysis of survey data collected between 2009 and 2013 and obtained from a sample of American Indian (AI) adolescents, attending schools located on or near American Indian reservations. Although recent statistical information indicates …
Modeling And Debiasing Feedback Loops In Collaborative Filtering Recommender Systems., Sami Khenissi
Modeling And Debiasing Feedback Loops In Collaborative Filtering Recommender Systems., Sami Khenissi
Electronic Theses and Dissertations
Artificial Intelligence (AI)-driven recommender systems have been gaining increasing ubiquity and influence in our daily lives, especially during time spent online on the World Wide Web or smart devices. The influence of recommender systems on who and what we can find and discover, our choices, and our behavior, has thus never been more concrete. AI can now predict and anticipate, with varying degrees of accuracy, the news article we will read, the music we will listen to, the movies we will watch, the transactions we will make, the restaurants we will eat in, the online courses we will be interested …
Functional Role Of Ppal And Potential For Moss In Industrial Applications., Susana Perez Martinez
Functional Role Of Ppal And Potential For Moss In Industrial Applications., Susana Perez Martinez
Electronic Theses and Dissertations
This dissertation is an examination and characterization of the functional roles of PPAL. PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT-LIKE (PPAL) is a recently discovered gene. PPAL homologs are present in all plants and many animals, where its function is largely unknown. It is possible that PPAL could participate in prenylation processes since it shares similarity to the α subunits of known prenylation enzymes. Prenylation is a post-translational modification of proteins that involves the addition of a lipid moiety to proteins to facilitate membrane targeting and association and promote protein-protein interactions. Prenylation has important roles in plant growth and development, including …
Etracellular Vesicles From Lactobacillus Rhamnosus Gg Protect Against Alcohol-Induced Liver Injury Through Suppression Of Intestinal Mir 194 And Subsequent Activation Of Fxr In Mice., Mengwei Jiang
Electronic Theses and Dissertations
Numerous studies have reported the efficacy of probiotics for alcohol-associated liver disease (ALD). These studies indicate a strong interest among the scientific and medical communities in identifying alternative or adjunctive approaches for ALD, for which there is no effective or widely accepted therapeutic option. However, in-depth molecular knowledge on how probiotics render their effects is lacking. Patients with ALD often have increased hepatic bile acids (BAs), which can be toxic and are an important causative factor in liver injury and hepatocyte death. BAs are released into the intestines and serve not only as a “detergent” to promote fat absorption, but …
Statistical Methods For Assessing Drug Interactions And Identifying Effect Modifiers Using Observational Data., Qian Xu
Electronic Theses and Dissertations
This dissertation consists of three projects related to causal inference based on observational data. In the first project, we propose a double robust to identify the effect modifiers and estimate optimal treatment. Observational studies differ from experimental studies in that assignment of subjects to treatments is not randomized but rather occurs due to natural mechanisms, which are usually hidden from the researchers. Many statistical methods to identify the treatment effect and select the optimal personalized treatment for experimental studies may not be suitable for observational studies any more. In this project, we propose a exible outcome model to select the …
Hiv And The African American Church: Millennial Faith Leader's Perspectives., Kelsey Leann Burton
Hiv And The African American Church: Millennial Faith Leader's Perspectives., Kelsey Leann Burton
Electronic Theses and Dissertations
African Americans are disproportionately impacted by HIV compared to other racial groups. Stigma surrounding HIV has created challenges for effective HIV prevention and stigma reduction programs. The African American church has been criticized for its slow and stigmatizing response to the HIV epidemic. Despite this, African American faith leaders play significant roles in guiding the perspective of the community. Numerous studies examine African American pastors’, faith leaders’, and ministers’ perspective about HIV and other HIV-related topics. However, there is no research that specifically examines young African American pastors’ perspectives of addressing HIV, stigma, and prevention. The purpose of this dissertation …
Surface-Functionalized Chemiresistive Films That Exploit H-Bonding, Cation-Pi, And Metal-Halide Interactions., Prasadanie Karunarathna Adhihetty
Surface-Functionalized Chemiresistive Films That Exploit H-Bonding, Cation-Pi, And Metal-Halide Interactions., Prasadanie Karunarathna Adhihetty
Electronic Theses and Dissertations
The development of gas sensors for detection of volatile organic compounds (VOCs) has been of interest in the sensing field for decades. To date, the use of metal nanoparticle-based chemiresistors for trace VOC detection, particularly gold nanoparticle-based sensors, is of great interest due to their high chemical stability, ease of synthesis, unique optical properties, large surface to volume ratio, and high level of conductivity. Much effort has been devoted towards gold monolayer protected clusters (Au MPCs) as chemiresistors to detect harmful VOCs. The present thesis documents the results of our efforts to exploit the advantages of functionalized Au MPCs chemiresistors …
Porphyromonas Gingivalis, Ethanol, And Chronic Diseases., Nicholas Alan Short
Porphyromonas Gingivalis, Ethanol, And Chronic Diseases., Nicholas Alan Short
Electronic Theses and Dissertations
This dissertation is an investigation into the relationships among Porphyromonas gingivalis, ethanol, and a series of chronic diseases, focusing primarily on atherosclerosis. It uses evolutionary theory to understand clinical parameters related to chronic disease biology. The initial research question was, "If people who drink a glass of wine each day have a lower risk for atherosclerosis, could one explanation involve antibacterial effects on pathogens associated with causing atherosclerosis, namely, Porphyromonas gingivalis?". This dissertation is divided into four chapters. Chapter One provides the foundational information pertinent to the dissertation. Chapter Two describes an in- vitro experiment aimed at understanding …
Learning The Language Of America: A Descriptive Phenomenolgical Study Of Black American Racial Conscientization., Kyee A Young
Learning The Language Of America: A Descriptive Phenomenolgical Study Of Black American Racial Conscientization., Kyee A Young
Electronic Theses and Dissertations
This transcendental phenomenological dissertation is an examination of the lived experience of Black American Racial Conscientization (RCZ). Worded differently, this descriptive phenomenological study investigated how Black Americans learn to perceive racial oppression and the various means by which they resist it. Fourteen in-depth interviews from within the epoché were conducted. The sample was heterogeneous with respect to age, ethnicity, socioeconomic status, educational attainment, career path, martial and parental status, sex, home and current state, and religious affiliation. The sample was homogeneous regarding citizenship status and gender identity. Data explication manifested 97 different codes that were then grouped into five situated …
Effects Of A Mindfulness-Based Intervention On Students' Academic Engagement, Frequency Of Disruptive Behavior, And Overall Mood States., Leah Riggs
Electronic Theses and Dissertations
Research into the prevalence of childhood trauma indicates that adverse experiences continue to negatively impact children and youth across the country. Current research is expanding the concept of trauma to include many children’s’ ongoing fear and worry surrounding the COVID-19 pandemic and experiencing the death of grandparents or other family and community members due to the virus. Symptoms of trauma may manifest in the classroom as behaviors that are attention seeking, defiant, destructive, hyperactive, disruptive, or all of the above. One emerging practice for meeting the needs of children who have experienced trauma is blending classroom behavior management and academic …
Structural, Charge Transport, Gas Sensing, Magnetic, Pseudocapacitive, And Electrocatalytic Properties Of Perovskite Oxides., Surendra Bahadur Karki
Structural, Charge Transport, Gas Sensing, Magnetic, Pseudocapacitive, And Electrocatalytic Properties Of Perovskite Oxides., Surendra Bahadur Karki
Electronic Theses and Dissertations
Perovskites are functional materials with the general formula ABO3 (A = alkali, alkaline earth or lanthanoid cations and B = transition metal or main group cations). These materials are marked by a variety of crystal structures and interesting properties such as colossal magnetoresistance, ferroelectricity, multiferroicity, superconductivity, pseudocapacitance, gas sensing, charge transport, and electrocatalytic properties. The formula of perovskite can be written as AA’BB’O6, when there is ordering between two cations over A and B-sites. Such compounds are called double perovskite oxides. Some amount of oxygen could be lost from crystal structure without decomposition of the phase. Such …
Engineering Lewis Acidic Materials For Biomass Conversion And Battery Applications., Md Anwar Hossain
Engineering Lewis Acidic Materials For Biomass Conversion And Battery Applications., Md Anwar Hossain
Electronic Theses and Dissertations
My long-term goal is to develop catalytic systems to produce renewable energy for a sustainable society. The overall research objective of my dissertation is to advance understanding of Lewis acidic materials for (1) conversion of renewable lignin into phenolics and (2) enhanced cycling stability of lithium metal batteries to safely store renewable electricity from wind and solar, thereby laying the groundwork for our transition to a sustainable society. Petroleum is a conventional feedstock for current transportation fuels (gasoline, diesel, and jet fuels). However, petroleum is a finite resource and produces greenhouse gases (CO2 and CH4) upon processing, …
Lysosomal Evasion Of Legionella Pneumophilia The Effector., Bethany Vaughn
Lysosomal Evasion Of Legionella Pneumophilia The Effector., Bethany Vaughn
Electronic Theses and Dissertations
Legionella pneumophila is a Gram-negative facultative intracellular bacterium found in freshwater environments that has co-evolved to survive and proliferate in various amoeba and protozoan species, which serve as the natural host for the bacterium. Humans are an accidental host of L. pneumophila, where infection occurs upon inhalation of aerosolized water droplets that contain the bacteria. Intracellular proliferation of L. pneumophila in alveolar macrophages is essential for manifestation of pneumonia, designated as Legionnaires’ Disease. Biogenesis of the legionella containing vacuole (LCV) occurs via interception of ER-Golgi vesicle trafficking and avoids the default endosomal/lysosomal degradation pathway. Intracellular proliferation of L. pneumophila …
"We Will Work A Lot And You Are So Loved": Teacher Perspectives On Building Positive Relationships With Students., Geena Constantin
"We Will Work A Lot And You Are So Loved": Teacher Perspectives On Building Positive Relationships With Students., Geena Constantin
Electronic Theses and Dissertations
This multiple case study using the Interpretive Phenomenological Analysis (IPA) approach (Alase, 2017) supported a need to understand the specific realities of student-teacher relationship-building. This investigation allowed a deeper look into four teachers’ perceptions of what it means to build positive relationships with students. This research study added to the literature demonstrating the importance of building strong positive relationships with students built on demonstrations of high expectations and care and driven by mutual understandings and celebration of diverse cultures and identities. Supporting this small group of teachers in investigating their personal beliefs about relationship-building was a step forward in defining …
Findings And Understandings Of 'Home': An Ethnographic Study Of How Homeless People And Displaced Persons Negotiate The Word 'Home'., Abby F Perez
Electronic Theses and Dissertations
This dissertation is an ethnographic study of various meanings of the word ‘home’ and how the word ‘home’ is used by homeless, evicted, and displaced persons, and by the researcher of the study, to negotiate boundaries and relations of power to achieve goals, both moral and material.Scholarly research on home in urban studies and sociology has produced many definitions and meanings of the word ‘home’ and concepts of home, but often neglects to consider the way the word itself is experienced, personally, by individuals and how to make sense of the way these personal experiences relate to official meanings of …
Finding The Silver Lining: The Role Of Affect And Adversity In Entrepreneurial Venturing., Lauren A. Zettel
Finding The Silver Lining: The Role Of Affect And Adversity In Entrepreneurial Venturing., Lauren A. Zettel
Electronic Theses and Dissertations
Motivated goal pursuit is a foundational concept in entrepreneurial venturing. Entrepreneurs set goals for their ventures, and their persistence in pursuing these goals ultimately impacts the success of their venture. Many of the explanations of motivation in goal pursuit have focused on the benefits of steady progress and positive emotions. However, entrepreneurs inevitably face adversity and setbacks which, in turn, beget negative emotions. It is yet unclear what role adversity and the ensuing negative emotions may have in motivating entrepreneurs. In order to extend our theoretical understanding of affect and adversity in entrepreneurial venturing, this dissertation draws on the existing …
Western Christianity And The Origins Of Antiblackness, Eurocentrism, And White Supremacist Ideology., John Chenault
Western Christianity And The Origins Of Antiblackness, Eurocentrism, And White Supremacist Ideology., John Chenault
Electronic Theses and Dissertations
This qualitative study investigates the cult(ural) and intellectual history of Western Christianity to address a significant gap in the literature pertaining to the origins of whiteness/antiblackness in the West and its subsequent socialization worldwide. Western Christianity’s seminal role in the social construction of the whiteness/antiblackness dichotomy has been undertheorized, neglected, and ignored. This study finds early Christian theologians categorically imposed conceptual metaphors about Blackness on African people that depicted them as the exemplars of evil to teach Christian doctrine about sin and salvation. It connects these original antiblack discourses directly to the theo-political arguments Western European Christians used centuries later …
Understanding Public Emergency Preparedness Before And During The Coronavirus Outbreak: Implications For Effective Public Health And Risk Communication., Raphael Adjetey Fumey
Understanding Public Emergency Preparedness Before And During The Coronavirus Outbreak: Implications For Effective Public Health And Risk Communication., Raphael Adjetey Fumey
Electronic Theses and Dissertations
The COVID-19 pandemic has resulted in a dramatic loss of human lives globally and presents an unprecedented challenge to public health, the world of work, and our food systems. The social and economic disruption caused by the COVID-19 pandemic is devastating, putting several millions of people at risk of falling into extreme poverty, with over 500 million people being undernourished. It is evident from the data on COVID-19 cases, deaths, and hospitalizations that the United States is the worse hit country, which can be attributed to the lack of preparedness at the individual, environmental, and government levels. This study applied …
Protest-Related Tear Gas Exposure And Menstrual Function, Emily Kathleen (Steinmetz) Reece
Protest-Related Tear Gas Exposure And Menstrual Function, Emily Kathleen (Steinmetz) Reece
Electronic Theses and Dissertations
During the racial justice protests of 2020 and 2021, crowd control chemical irritants (referred to as “tear gas”) were deployed against protesters, after which there were anecdotal reports of altered menstrual cycles among exposed individuals. There is only one peer reviewed published study on tear gas exposure and menstrual health. This study examined whether tear gas exposure was associated with menstrual cycle outcomes among women attending the 2020-2021 protests. Data from 103 women who attended racial justice protests in 2020 and 2021 were collected through an online questionnaire. Data included protest attendance, acute symptoms of tear gas exposure, whether medical …
Person-Centered Decision-Making And Socio-Cultural Contexts Influencing Cesarean Deliveries: A National Analysis., Alice M. Story
Person-Centered Decision-Making And Socio-Cultural Contexts Influencing Cesarean Deliveries: A National Analysis., Alice M. Story
Electronic Theses and Dissertations
The cesarean delivery rate has increased and accounts for a third of pregnancies in the U.S., especially among marginalized women. This study applied a newly developed conceptual model to identify potential areas of influence that could reduce rates of cesarean deliveries. The Giving Voice to Mothers - United States data was used for analyses to predict covariates associated with having a cesarean delivery vs. spontaneous vaginal delivery (n=1,876). Significant covariates were determined and included the following: having a prior cesarean delivery (OR: 14.11, 95% CI: 7.99 - 24.90); more than one child (OR: 0.21, 95% CI: 0.13 - 0.35); elevated …
Determinants Of Caregiver Burden Among Informal Caregivers Looking After Older Adults With Alzheimer's Disease In Saudi Arabia., Sultan Ali Shubair
Determinants Of Caregiver Burden Among Informal Caregivers Looking After Older Adults With Alzheimer's Disease In Saudi Arabia., Sultan Ali Shubair
Electronic Theses and Dissertations
Caregiver burden in Alzheimer’s Disease (AD) is a significant factor in the deterioration of caregivers’ physical and mental health. Moreover, increased caregiver burden has been associated with the decline in quality of life and the reduced quality of care for the care recipient. However, the level of caregiver burden perceived by informal caregivers of care recipients with AD can be varied with the impact of different factors related to the caregiver, care recipient, and caregiving process. Identifying factors associated with caregiver burden and exploring factors that account for variation in caregiver burden are vital to prevent adverse outcomes of caregiver …
“I Think It's Male Privilege”: A Qualitative Study Of Personal, Behavioral, And Socio-Environmental Factors Influencing High Risk Sexual Behavior And Hiv Transmission Among Heterosexual Adult Males In Ghana., Nana Ama Aya Erzuah Bullock
“I Think It's Male Privilege”: A Qualitative Study Of Personal, Behavioral, And Socio-Environmental Factors Influencing High Risk Sexual Behavior And Hiv Transmission Among Heterosexual Adult Males In Ghana., Nana Ama Aya Erzuah Bullock
Electronic Theses and Dissertations
There are roughly 340,000 adults and children living with HIV. Despite the progress in the global response and the lowing of infections, HIV rates in Ghana remain stable. Cultural and societal norms that exist at a given time and place influence masculine socialization and behavior. These norms promote heterosexual men’s engagement in high-risk sexual behaviors which result in HIV infections. Factors such as HIV knowledge, risk perception, male condom use, HIV testing, and counseling which minimize the risk of HIV, are also influenced by these norms. Men have been identified as assets and advocates for behavior change and social responsibility …
The Underbelly Of Residential Segregation, Bussing To Integrate And The Educational Ramifications: A Case Study Of Louisville Kentucky., Camara Douglas
The Underbelly Of Residential Segregation, Bussing To Integrate And The Educational Ramifications: A Case Study Of Louisville Kentucky., Camara Douglas
Electronic Theses and Dissertations
Integration of the American public school system is often examined to figure out if integration worked. This dissertation examined busing to integrate into Louisville, Kentucky. Busing to integrate in Louisville, Kentucky, took place during that 1975-1976 school year. Louisville’s case is somewhat different. Not only did they finally follow federal mandates to integrate, they had to mix two totally separate school systems, one for the county (White) and one from the city (African American). The objectives are: (1) what were the experiences and perceptions of African American students in high school who lived in the West Louisville hyper-segregated neighborhoods and …
A Modeling Platform To Predict Cancer Survival And Therapy Outcomes Using Tumor Tissue Derived Metabolomics Data., Hunter Allan Miller
A Modeling Platform To Predict Cancer Survival And Therapy Outcomes Using Tumor Tissue Derived Metabolomics Data., Hunter Allan Miller
Electronic Theses and Dissertations
Cancer is a complex and broad disease that is challenging to treat, partially due to the vast molecular heterogeneity among patients even within the same subtype. Currently, no reliable method exists to determine which potential first-line therapy would be most effective for a specific patient, as randomized clinical trials have concluded that no single regimen may be significantly more effective than others. One ongoing challenge in the field of oncology is the search for personalization of cancer treatment based on patient data. With an interdisciplinary approach, we show that tumor-tissue derived metabolomics data is capable of predicting clinical response to …
Mission Drift And The Effectiveness Of Resource Dependence Theory In An Internally Resource-Constrained Environment., Kirsten Bullock
Mission Drift And The Effectiveness Of Resource Dependence Theory In An Internally Resource-Constrained Environment., Kirsten Bullock
Electronic Theses and Dissertations
Why are some organizations able to maintain focus on their mission while others founder? This theoretical and empirical dissertation examines the relationships among funding sources, management practices, and organizational stigma within an internally resource-constrained environment. Using Resource Dependence Theory (RDT) as a basis to manage external resource dependencies, I build a theoretical model and empirically test a research model to understand how funding source affects mission drift, how management practices might help organizations manage that drift, and what effect organizational stigma might have on those relationships within an environment of internal resource constraints. Specifically, this study hypothesizes that nonprofits that …