Digital Commons Network^™

The International Perception Of The Irish Republican Army And Chechen Insurgency, Henry Forteith

International and Global Studies Undergraduate Honors Theses

This purpose of this project is to examine how the labels used to describe the Irish Republican Army and Chechen insurgency changed after certain acts of violence. This paper begins by describing the history of imperial subjugation of Ireland and Chechnya, as well as examining the similarities between the actions and motivations of the IRA and Chechen insurgency. Then, to study the change in language to describe these groups, two searches were conducted into the New York Times and International Newsstream databases. The first search examined articles about the IRA and Chechen insurgency published between 1998 and 2009, while the …

A Tale Of Two Libraries: A History Of The Public Library Systems Of Atlanta, Ga And Baltimore, Md And How Libraries Across America Adapt To Their Communities, Gigi Powell

History Undergraduate Honors Theses

Public libraries are a staple American institution, and one that was created to adapt and react to its surrounding communities. Public libraries are unique in their ability to anticipate and fill a community’s needs, as evidenced by their constant evolution to remain relevant and provide up- to-date services to all users. To highlight this evolution, librarians from both the Fulton County Public Library System in Atlanta, GA and the Enoch Pratt Free Library system were interviewed to gauge what the library’s role is in a modern world, in a world newly ravaged by COVID-19, and how that role has evolved …

The Political Power Of Museums: A Case Study On The Museum Of Spanish Colonial Art, Emily Snyder

History Undergraduate Honors Theses

Museums hold an esteemed position that grants validity to the objects and history held within them based solely on their inherent authority as institutions. This makes the analysis of what museums portray incredibly important given the extent of people’s belief that they hold the power to determine authoritative truth concerning art, history, and society. In the late 1970s, museums underwent a period of change tied to becoming more pluralistic. Beginning in the 1990s, many museums touted their postcolonial status in the wake of their inclusion of and collaboration with traditionally outsider communities. Despite this change appearing to create more diverse …

World Changers Made Here., Andrea Luxton

Lake Union Herald

No abstract provided.

Ocul Collaborative Futures (Cf) Decolonizing Descriptions Working Group Final Report, Erin Johnson, F. Tim Knight, Antonio Muñoz Gómez

Librarian Publications & Presentations

The broad objective of the working group is to develop recommendations on how to make descriptive metadata in Omni, the Collaborative Futures (CF) shared library services platform, more accurately and respectfully reflect Indigenous Peoples, knowledges, and contexts.

The following report was created by the OCUL-CF Decolonizing Descriptions Working Group and submitted to the OCUL-CF Metadata Management and Standards Committee as per its Terms of Reference.

In section 1 of the report, we have included a set of recommendations organized as follows:

● Recommendations on relationship building and consultation: The Working Group recognized that without this step, this work cannot advance …

The Use Of Spectral Imaging To Reveal Inorganics And Organics Identity In The Biological Samples, Qamar Alshammari

Pharmaceutical Sciences (PhD) Dissertations

The wavelength is used to identify the exact location and quantify the number of molecules in the spectral imaging system. It aids in identifying materials and studying their quantities by examining how they interact with light. A traditional spectrometer provides spectrum information of chemical compounds, while standard imaging provides the intensity at each pixel of the image. Spectral imaging (SI) combines these two aspects by equipping intensity and spectral data for each pixel. In biomedical research, it is important to assess the inorganics/organics molecules to understand drug activity, cellular toxicity, and distribution. Using the microscopy technique, we found for the …

Newsletter May 2022, Mandarin Garden Club

Mandarin Garden Club Newsletters

Club News

Why Renegotiation?: Renewal Of The South Korea-Chile Bilateral Free Trade Agreement, Montserrat Bugueno

International Studies (MA) Theses

This thesis project explores the motivations behind the bilateral free trade agreement (FTA) renegotiation between Chile and South Korea. Existing studies have examined the reasons and outcomes of creating the initial Chile-South Korea FTA, but they have not focused on renegotiations between the two countries. A few investigations on renegotiations have focused on diversifying their exports and expanding their markets in each other's regions. However, most research lacks further exploration of both countries' market security concerns. By analyzing official government documents and conducting three semi-structured interviews with government officials and experts in the field, I argue that the current protectionist …

Tennessee Abortion Policy Summary - May 2022, Center For Applied Reasearch And Evaluation In Women's Health, East Tennessee State University

Center for Applied Research and Evaluation (CARE) in Women's Health Issue Briefs

With the U.S. Supreme Court anticipated to overturn the 1973 Roe v. Wade decision (and the modifications to that decision by Planned Parenthood of Southeastern Pennsylvania v. Casey from 1992), the protection, regulation, or prohibition of abortion would likely default to state laws and state constitutions. Therefore, to understand how this upcoming Supreme Court decision could impact access to abortion in Tennessee, it is useful to examine both key current state laws in effect related to abortion access, as well as the current state of access to abortion in Tennessee. This brief intends only to summarize current Tennessee state laws …

The Design, Prototype, And Testing Of A Robotic Prosthetic Leg, Michael Davidson

Loma Linda University Electronic Theses, Dissertations & Projects

Since antiquity, health professionals have sought ways to provide and improve prosthetic devices to ease the suffering of those living with limb loss. Mid-century modern engineering techniques, in part, developed and funded by the American industrial war effort, led to numerous innovations and standardization of mass-customized products. Followed by the Digital Revolution, we are now experiencing the roboticization of prosthetic limbs. As innovations have come and gone, some essential technologies have been forgotten or ignored. Many successful products have been commercialized, but unfortunately, they are often rationed to those who need them most. Here we present a prototype device based …

Strategies For Protection Of The Blood Brain Barrier In Rodent Models Of Intracerebral Hemorrhage, Derek Sunil Nowrangi

Loma Linda University Electronic Theses, Dissertations & Projects

Intracerebral Hemorrhage (ICH) is a devastating disease that causes a cascade of both mechanical and molecular injury to the central nervous system. It is a debilitating disease that has no well-established treatments, thus leaving an important area to study the pathophysiology of the disease so that new clinically translatable treatments can be found. In the development of translational treatments in experimental ICH, several challenges exist including the designing of studies, method to deliver drugs, proper dosages, and development of models. In our exploration to establish new therapies for ICH, we studied several methods and models that may help to develop …

An Investigation Of The Anti-Stemness Actions Of Two Mirnas After Their Induction By Aminoflavone In Luminal A Breast Cancer, Nicole Ursula Rumbidzai Mavingire

Loma Linda University Electronic Theses, Dissertations & Projects

Approximately 40% of estrogen receptor positive breast cancer (BC) patients develop resistance to endocrine therapy (ET) agents like tamoxifen (Tam). Resistance promotes metastasis, recurrence, and death since metastatic BC is often incurable. Breast cancer stem cells (CSCs) greatly contribute to disease progression and drug resistance. We previously showed that aryl hydrocarbon receptor (AhR) agonist aminoflavone (AF) inhibits the expression of CSC biomarker α6-integrin (ITGA6) to disrupt the formation of endocrine-sensitive and -resistant luminal A mammospheres. In this study, we performed miRNAsequencing analysis of luminal A MCF-7 and MCF-7TamR mammospheres before and after AF treatment to further develop the mechanism of …

Phytochemical And Synthetic Ahr Ligands As Novel Therapy For Refractory Breast Cancer, Jonathan V. Wooten

Loma Linda University Electronic Theses, Dissertations & Projects

Patients with triple-negative breast cancer (TNBC) possess tumors that lack estrogen receptor, progesterone receptor, and human growth factor receptor 2 expression. Such patients have lower survival rates than those diagnosed with other breast cancer subtypes in part, due to the scarcity of targeted therapy for TNBC. In addition to chemotherapy, patients with TNBC often consume natural remedies, which has led us and others to evaluate the ability of plant isolates to confer anticancer and chemopreventive actions. Poly-ADP ribose polymerase (PARP) is an enzyme that promotes DNA single-strand break repair. PARP inhibitor olaparib exploits DNA repair enzyme deficiency in tumors to …

Through The Leaves: Understanding Population Genetic Structure Of Clematis Morefieldii, Keith Andrew Greenway

Honors Capstone Projects and Theses

No abstract provided.

Digital Commons @ Andrews University Annual Report 2021-2022, Terry Dwain Robertson

Library Administration and Marketing

Report covers May 2020-April 2021

Table of Contents

• About the Digital Commons @ Andrews University
• Five Millionth Download
• Global Impact
• Serving the SDA World Church
• “Letting Your Light Shine”: Faculty Scholarship in SelectedWorks
• 2000 Faculty Publications Added

Authentic Leadership As Practiced By Wabanaki Leaders, Ashlyn Tomer Ma

Leadership Studies

Native American leaders of the Wabanaki community can provide great insight on how to build positive close-knit relationships within a community. Previous research has focused on other tribal nations such as the Cherokee and servant leadership. But few studies have explored authentic leadership in the Wabanaki community. Authentic leadership occurs naturally in the Wabanaki Nation through their cultural upbringing and the leaders' authenticity projects back into the community. This phenomenology study explores authentic leadership within the Wabanaki Nation and how it contributes to the cultivation of positive relationships within the community. Ten leaders and advocates of the Wabanaki community participated. …

A Machine-Verified Proof Of Linearizability For A Queue Algorithm, Ugur Yavuz

Dartmouth College Master’s Theses

Proofs of linearizability are typically intricate and lengthy, and readers may find it difficult to verify their correctness. We present a unique technique for producing proofs of linearizability that are fully verifiable by a mechanical proof system, thereby eliminating the need for any manual verification. Specifically, we reduce the burden of proving linearizable object implementations correct to the proof of a particular invariant whose correctness can be shown inductively. Noting that the latter is a task that many proof systems (such as the TLA+ Proof System we chose to work with) are well-suited to handle, this technique allows us to …

Fungal Fruiting And Dispersal Following Timber Harvest, Benjamin William Borgmann-Winter

Master's Theses and Capstones

Forest-dwelling fungi are critical to ecosystem function in their roles as decomposers and nutrient cyclers, food sources, pathogens, and mycorrhizal symbionts. In northern New England, a region with a substantial timber industry, the degree to which fungal communities are resilient to timber harvest, as well as their ability to recolonize post-disturbance, may impact ecosystem function and forest regeneration. In this thesis, we investigate the impacts of (1) timber harvest on fungal fruiting, an important element of fungal reproduction, and (2) the dispersal mechanisms by which fungi may re-colonize harvested areas. In Chapter 1, we investigate the impact of timber harvest …

Gli3 And P300: Modulating Inflammatory Cytokine Production In Monocytes, Storm Devin Gardner

Master's Theses and Capstones

GLI3 is an important protein traditionally found in the Sonic Hedgehog pathway. It is involved in numerous events that take place during embryogenesis such as the differentiation and patterning of cells in the body. Monocytes are important innate immune cells which infiltrate the site of inflammation when a pathogen invades our body. Gli3 has also been shown to be upregulated in monocytes following pathogen stimulation, suggesting Gli3 could have an important role in mediating the release of inflammatory signals known as cytokines. The histone acetylase protein p300 traditionally acetylates histones to epigenetically modify them to allow DNA unwinding and subsequently …

Improving Larval And Juvenile Lumpfish, Cyclopterus Lumpus, Aquaculture: Nutrition And Growing Conditions, Nathaniel Spada

Master's Theses and Capstones

Salmonids play a major role in aquaculture globally and their production is expected to increase as the human population rises and wild fish stocks decline. Sea lice infestation is the largest economic burdens to salmonid net pen aquaculture with hundreds-of-millions of dollars lost due to the treatment, labor, and loss of biomass associated with these parasitic copepods. Chemotherapeutics were originally used to treat these infestations, but their effects on nontarget species resulted in them being banned in many countries. Many salmonid farmers now utilize cleanerfish technology to resolve this financial stressor. Lumpfish (Cyclopterus lumpus) are efficient delousers in salmonid aquaculture …

Uv Sulfite Advanced Reduction Process For Pfos Transformation In Wastewater Treatment, Cassidy Rae Yates

Master's Theses and Capstones

Most nutrients and contaminants within municipal wastewaters are removed through physical, chemical, and biological treatment methods. Per- and polyfluoroalkyl substances (PFAS) are a class of contaminants of emerging concern (CECs) that are concentrated in wastewater treatment facilities (WWTFs) from municipal, industrial, and commercial sources in communities. PFAS are poorly removed in conventional municipal wastewater treatment because these facilities are generally not designed for treatment of low-level CECs. Some PFAS leave WWTFs through aqueous effluent, while others partition to solids and are handled in sludges due to properties based on the degree of fluorination, chain length, and headgroup. As the last …

Evaluating First Responder Personal Preparedness In Douglas County, Nebraska's Volunteer Fire And Emergency Medicine Service, Kylie Johnson

Capstone Experience: Master of Public Health

In disaster response, it is essential for first responders to focus on their disaster role. Lack of personal preparedness at home could hinder a responder’s ability to focus their attention on their response role (13). Personal conflict, such as that caused between family duties and response duties, in a disaster can be mitigated through several means. One mitigation tactic is preparedness education and support offered by the responder’s organization. While the importance of responder personal preparedness cannot be understated, there is a lack of baseline data on the topic related to Nebraska responders.

To assess the state of first responder …

Using Experiments, 3d Scanning, And Computational Fluid Dynamics To Analyze Variance In Minor Loss Coefficients, Adam B. Pack

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

As water moves through pipes, it loses energy. The energy losses are due to friction and the minor losses associated with various pipe fittings, which change the direction of flow. Pipe bends, or elbows, are a common pipe fitting and a significant source of energy loss in piping systems. This research was performed to better understand the variability of energy loss due to different pipe elbow designs and to investigate methods to replicate these losses using numerical simulations.

Eight pipe elbows, all 3-inch, 90-degree, schedule 40 PVC elbows that vary by radius of curvature and/or end connection type, were tested …

Bivalve Restoration Suitability Analysis, Sara Bandali, Kayla Garcia, Derek Bostelman, Georgina Quinn

Student Projects

Cal Poly Humboldt Environmental Science and Management: ESM 475 Planning and Policy Capstone Practicum.

The goal of this project is to provide Humboldt Baykeeper with a report of potential designs, sites, benefits, and stakeholder opinions related to developing a native Olympia oyster and clam garden restoration pilot project on Wigi. This suitability analysis will examine several different locations across the bay and compare the feasibility of (1) an Olympia oyster restoration, (2) an Olympia oyster living shoreline restoration for sea-level rise, and (3) a clam garden restoration. Based on our research, we will provide an analysis of four sites in …

Annual Report Of The Nominating Committee For The Academic Year 2021-2022, University Of Northern Iowa. Faculty Senate.

Documents - Faculty Senate

University Nominating Committee report including committee memberships, produced by the Faculty Senate of the University of Northern Iowa.

Novel Regulators Of Cellular Secretion Alter The Tumor Microenvironment To Drive Metastasis, Rakhee Bajaj

Dissertations and Theses (Open Access)

Lung cancer is a highly aggressive disease responsible for ~25% of all cancer-related deaths, due in part to its proclivity to metastasize. Treating metastasis holds potential for improving patient survival but requires a deeper investigation into the underlying mechanisms. Some of these processes that can regulate metastasis are: (1) Oncogenic targets of epithelial micro-RNAs (miRNAs) are epigenetically de-repressed upon loss of the miRNAs during epithelial-to-mesenchymal transition (EMT) and in cancer. EMT confers plasticity and fitness to cancer cells promoting their survival through the metastatic cascade. This cascade and EMT are initiated by loss of the miRNA200 family (miR-200) and the …

Parental Stress In Tuberous Sclerosis Complex, Jenny Do

Dissertations and Theses (Open Access)

Tuberous Sclerosis Complex (TSC) is a multi-systemic genetic disorder with great clinical variability. As the needs of one child with TSC may vastly differ from another, parenting demands may similarly differ. Characterizing parental stress, or emotional maladaptation arising from parenting duties, can enable healthcare providers to assist parents of children most efficiently with TSC-related symptoms and improve both parent and child health outcomes. This study surveyed 269 parents of children (aged 0-12 years) with TSC and received the following information: children’s TSC clinical features, parent demographics, and a Parent Stress Index (PSI) score. Parents reported higher stress levels for children …

Prenatal Testing Decisions And Motivations In Pregnancies Conceived Via In Vitro Fertilization, Michelle Appel

Dissertations and Theses (Open Access)

Currently, there is limited information about how conceiving through in vitro fertilization (IVF) and preimplantation genetic testing for aneuploidy (PGT-A) impact the decisions individuals make about prenatal genetic testing. This quantitative study aimed to examine the prenatal testing decisions made by pregnant individuals who conceived via IVF as well as to compare the prenatal testing decisions and motivations between those who had PGT-A and those who did not. An anonymous survey was distributed through online support forums and in clinical settings to eligible individuals. Overall, 230 complete responses were collected with 203 participants far enough along in pregnancy to make …

Atr-Mediated Cd47 And Pd-L1 Upregulation Restricts Radiotherapy-Induced Immune Priming And Abscopal Responses In Colorectal Cancer, Cheng-En Hsieh, Cheng-En Hsieh

Dissertations and Theses (Open Access)

Radiotherapy of colorectal cancer (CRC) can prime adaptive immunity against tumor-associated antigen (TAA)-expressing CRC cells systemically. However, incidences of abscopal tumor remission are extremely rare, and the post-irradiation immune escape mechanisms in CRC remain elusive. We report that CRC cells utilize a common DNA repair signaling pathway — ATR/Chk1/STAT3 — to upregulate both CD47 and PD-L1 in response to radiotherapy, which through engagement of SIRPα and PD-1 suppresses the capacity of antigen-presenting cells to phagocytose them thereby preventing TAA cross-presentation and innate immune activation. This post-irradiation CD47 and PD-L1 upregulation can be observed across various human solid tumor cells. Concordantly, …

Development Of The Ark Assay For Quantitating Dna- Protein Crosslink Accumulation And Fanconi Anemia Pathway Involvement In The Repair Process, Naeh Klages-Mundt

Dissertations and Theses (Open Access)

DNA-protein crosslinks (DPCs) are a common DNA lesion naturally arising in cells, wherein protein becomes covalently and irreversibly bound to the DNA. Given their excessive size, these adducts present a significant challenge to replication and transcription, thus requiring timely and efficient repair. However, the precise mechanisms involved with processing DPC removal remain unclear. Moreover, current methodologies to quantitate DPC accumulation and removal are restrained by a range of limitations. Here, we describe and discuss a new DPC detection assay – the ARK assay – capable of overcoming the limitations incurred by prior assays. The design, which uses dual chaotropic lysis …