Digital Commons Network^™

Resilience And Health Of Older Women Who Have Experience Intimate Partner Violence Earlier In Life, Tenna R. Schumacher

Dissertations

When a traumatic event such as intimate partner violence occurs, resilience can help define recovery from that event. Women who experience the adverse event of intimate partner violence suffer injury, loss of physical and mental health, and possible death. Specifically, numerous women suffer injury and adverse health as a result of experiencing intimate partner violence (Krug, Mercy, Dahlberg, & Zwi, 2002). The internal quality of resilience is what allows a person to mend or heal from trauma (Wagnild, 2009). Resilience is demonstrated by hardiness of spirit and a person's ability to return to their lifestyle (Atkinson, Martin, & Rankin, 2009; …

Newman, Ellen, Sophia Maier Garcia

Bronx Jewish History Project

Ellen Newman was born in 1953 in Bronx Hospital. Both sets of grandparents had immigrated to New York City as young children and her parents were both raised in the Bronx. She attended PS 114, by Yankee Stadium, Macombs Junior High School, Taft High School, and Lehman College for both her bachelor’s and master’s. Her family would go to upstate New York in the summers, and her father was an accountant and her mother was a bookkeeper. Newman lived in the Highbridge neighborhood of the Bronx until her family moved to Scott Towers, a Mitchell Lama Co-op. The Highbridge neighborhood …

Sustainable Building Without Certification: An Exploration Of Implications And Trends, Yewande Abraham, Lisa Greenwood, Jennifer Schneider

Articles

Background: Sustainable buildings play a pivotal role in meeting the United Nations Sustainable Development Goals (UN SDGs). However, the criteria and process for certification associated with sustainable building rating systems have been seen by many as either cumbersome or too expensive. As a result, some buildings are constructed following sustainable building guidelines without necessarily pursuing external certification. This paper takes a critical look at sustainable building without certification in the US and addresses 3 questions: (1) What is the rationale behind not pursuing certification? (2) When certification is not part of the objective, how are particular sustainability criteria selected? (3) …

Case Law On American Indians, Thomas P. Schlosser

American Indian Law Journal

No abstract provided.

Quantitative Proteomic Analyses Of Human Plasma: Application Of Mass Spectrometry For The Discovery Of Clinical Delirium Biomarkers, Kwame Wiredu

Dartmouth College Ph.D Dissertations

The biomarker discovery pipeline is a multi-step endeavor to identify potential diagnostic or prognostic markers of a disease. Although the advent of modern mass spectrometers has revolutionized the initial discovery phase, a significant bottleneck still exists when validating discovered biomarkers. In this doctoral research, I demonstrate that the discovery, verification and validation of biomarkers can all be performed using mass spectrometry and apply the biomarker pipeline to the context of clinical delirium.

First, a systematic review of recent literature provided a birds-eye view of untargeted, discovery proteomic attempts for biomarkers of delirium in the geriatric population. Here, a comprehensive search …

Pivotal Trial Of Mri-Guided Transurethral Ultrasound Ablation In Men With Localized Prostate Cancer: Three-Year Follow-Up, Steven S. Raman, Sandeep Arora, Katarzyna J. Macura, Aytekin Oto, Jurgen Fütterer, Robert Staruch, Temel Tirkes, David Bonekamp, Masoom Haider, Derek W. Cool, Kiran Nandalur

Conference Presentation Abstracts

Purpose: MRI-guided transurethral ultrasound ablation (TULSA) of prostate tissue is a novel directional ultrasound heating under real-time MRI thermometry feedback control. We report 3-year outcomes from the pivotal TULSA-PRO Ablation Clinical Trial. Materials and Methods: With IRB approval and HIPAA compliance, 115 men with organ-confined prostate cancer (≤T2b, PSA ≤15 ng/ml, Grade Group [GG] 1-2) across 13 centers underwent whole-gland ablation sparing the urethra, bladder neck, and urinary sphincter. Primary endpoints were safety and PSA reduction at 1 year. Secondary endpoints: prostate volume reduction, mpMRI, and 10 core biopsy at 1 year; quality of life, PSA, and salvage to 3 …

Empire And Politics In Eastern And Western Civilizations, Mortimer N.S. Sellers

All Faculty Scholarship

To speak of “empire” today is to evoke the history of China and of Rome, two great empires that vastly influenced the culture and development of half the globe. The whole world has been touched by their powerful examples, so that even someone writing, as I do, in a distant corner of North America, feels the history and influence of the Roman and Chinese empires every day. Nor are they unique. Something like “empire” has arisen wherever there was wealth and stability to support it. Rome and China had numerous rivals in the East and West who aspired to empire …

Evaluating Countable Texture Elements To Represent Bathymetric Uncertainty, Colin Ware, Christos Kastrisios

Center for Coastal and Ocean Mapping

Measurements of the depth of the seabed vary widely in both horizontal and vertical accuracy. To convey this information to mariners, Zones of Confidence (ZOC) are defined for charts. A mosaic of ZOCs can be represented as a chart overlay. This study evaluates two novel designs for textures to represent ZOCs. Both use textures with countable elements to represent different ZOC levels. One uses a texture made of lines where the number of lines in a texture cell represents the confidence level; the other uses dot clusters where the number of dots similarly represents the ZOC level. In the study, …

Associations Of Maternal Lipoprotein Particle Distribution In Mid-Pregnancy With Birth Outcomes: A Pilot Study., Todd C. Rideout, Xiaozhong Wen, Divya Choudhary, Marissa Catanzaro, Richard W. Browne, Vanessa M. Barnabei, Kai Ling Kong

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: An excessive rise in maternal lipids during pregnancy may have detrimental impacts on maternal and fetal health leading to adverse pregnancy outcomes. However, knowledge gaps exist with respect to the association between lipid biomarkers and birth outcomes.

METHODS: We conducted a secondary data analysis of healthy pregnant women (N = 25) with mid-pregnancy fasting serum samples collected at 22-28 weeks of gestation and birth outcome data. Serum was analyzed for conventional lipid profile (total-C, HDL-C, LDL-C, and triglycerides) and lipoprotein subclass distribution, including particle number (nM) and size (nm), for very low-density lipoprotein (VLDL)/chylomicron (CM), low density lipoprotein (LDL), …

A Long-Acting Interleukin-7, Rhil-7-Hyfc, Enhances Car T Cell Expansion, Persistence, And Anti-Tumor Activity, Miriam Y Kim, Reyka Jayasinghe, Jessica M Devenport, Julie K Ritchey, Michael P Rettig, Julie O'Neal, Karl W Staser, Krista M Kennerly, Alun J Carter, Feng Gao, Byung Ha Lee, Matthew L Cooper, John F Dipersio

Open Access Publications

Chimeric antigen receptor (CAR) T cell therapy is routinely used to treat patients with refractory hematologic malignancies. However, a significant proportion of patients experience suboptimal CAR T cell cytotoxicity and persistence that can permit tumor cell escape and disease relapse. Here we show that a prototype pro-lymphoid growth factor is able to enhance CAR T cell efficacy. We demonstrate that a long-acting form of recombinant human interleukin-7 (IL-7) fused with hybrid Fc (rhIL-7-hyFc) promotes proliferation, persistence and cytotoxicity of human CAR T cells in xenogeneic mouse models, and murine CAR T cells in syngeneic mouse models, resulting in long-term tumor-free …

Use Of Early Specialty Hesi Exams As Predictors Of Hesi Exit Examination Performance In Baccalaureate Degree Nursing Program, Cathy E. Hansen

Dissertations

This study explored standardized testing outcomes used early in a baccalaureate nursing (BSN) education program in traditional and second-degree students in order to identify predictors of outcome on the program exit examination (HESI E²). Defining early predictors of student outcomes may more accurately identify student need for early intervention, offer timely remediation, optimize success, and minimize attrition in nursing education programs. The purpose of this correlational quantitative study was to determine if a relationship exists between student outcomes on four HESI specialty exams (fundamentals, health assessment, pathophysiology, and pharmacology) and the performance outcomes on the HESI E^{2 …}

20220613: Corbly Hall, 1988-2010, Buildings And Grounds

Guides to University Archives

These items include materials from what is now known as Physical Plant and Facilities at Marshall University from 1988-2010. Items were received at an earlier date but were not inventoried until 2022. Items within this collection have to do with Corbly Hall and its various projects to renovate and remodel over the years (e.g. Boiler replacements, masonry and roof renovations and improvements, and the maintenance manual). This is not an exhaustive list, but the attached inventory will give a broad overview of what is contained in each of the boxes.

Synthesis And Applications Of Α,Β-Dehydroamino Acid-Containing Peptides, Diego A. Moya

Theses and Dissertations

Yaku’amide A (YA) is a linear anticancer peptide that is rich in bulky dehydroamino acids (ΔAAs) and β-hydroxyamino acids (β-OHAAs). In our recent total synthesis of YA, we featured a one-pot anti dehydration–azide reduction–O→N acyl transfer process for the stereospecific construction of Z- and E- ∆Ile residues. Despite previous total syntheses and our efforts, the synthesis of YA remains lengthy. Via computational studies, we identified two analogue peptides that closely resemble the conformation of YA. The use of simpler and symmetrical bulky ΔAAs such as dehydrovaline (ΔVal) and dehydroethylnorvaline (ΔEnv) as surrogates of ∆Ile, along with azlactone chemistry for their …

Draft Final 2022 Residential Metals Abatement Program (Rmap) Quality Assurance Project Plan (Qapp) (Non-Residential Parcels), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Draft Final 2022 Residential Metals Abatement Program (Rmap) Quality Assurance Project Plan (Qapp) (Non-Residential Parcels), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Wild Bees Respond Differently To Sampling Traps With Vanes Of Different Colors And Light Reflectivity In A Livestock Pasture Ecosystem, Roshani S. Acharya, Joan M. Burke, Timothy Leslie, Kelly Loftin, Neelendra K. Joshi

Entomology Faculty Publications and Presentations

Wild bees are important pollinators and monitoring their abundance and diversity is necessary to develop conservation protocols. It is imperative to understand differences in sampling efficiency among different trap types to help guide monitoring efforts. This study used a new vane trap design to collect bees in a livestock pasture ecosystem and examined the impact of six different vane colors on wild bee sampling. We recorded 2230 bees comprising 49 species and five families. The most abundant species were Augochlorella aurata (25.8%), Lasioglossum disparile (18.3%), Lasioglossum imitatum (10.85%), Agapostemon texanus (10.8%), Melissodes vernoniae (9.9%) and Halictus ligatus (4.7%). Traps with …

Assessing Covid-19 Testing Strategies In K-12 Schools In Underserved Populations: Study Protocol For A Cluster-Randomized Trial, Samantha Hayes, Sara Malone, Brittany Bonty, Nancy Mueller, Summer M Reyes, Sydney A Reyes, Christina Evans, Myisha Wilcher-Roberts, Tremayne Watterson, Sewuese Akuse, Jamee Shelley, Grace Yuan, Ian Lackey, Jasmine Prater, Brock Montgomery, Cynthia Williams, Sheretta T Butler-Barnes, Kelly Harris, Charlene Caburnay, Nikole Lobb Dougherty, Jingxia Liu, Albert Lai, Julie Neidich, Stephanie Fritz, Jason G Newland

2020-Current year OA Pubs

BACKGROUND: Since March 2020, COVID-19 has disproportionately impacted communities of color within the United States. As schools have shifted from virtual to in-person learning, continual guidance is necessary to understand appropriate interventions to prevent SARS-CoV-2 transmission. Weekly testing of students and staff for SARS-CoV-2 within K-12 school setting could provide an additional barrier to school-based transmission, especially within schools unable to implement additional mitigation strategies and/or are in areas of high transmission. This study seeks to understand the role that weekly SARS-CoV-2 testing could play in K-12 schools. In addition, through qualitative interviews and listening sessions, this research hopes to …

Primary Prevention Of Stroke In Children With Sickle Cell Anemia In Nigeria: Protocol For A Mixed Methods Implementation Study In A Community Hospital, Halima Bello-Manga, Lawal Haliru, Kudrat Abdulkareem Ahmed, Abdulkadir Musa Tabari, Bilkisu Usman Farouk, Gloria Yimi Bahago, Aisha Shuaibu Kazaure, Abdulrasheed Sani Muhammad, Samira Abubakar Gwarzo, Ana A Baumann, Michael R Debaun, Allison A King

2020-Current year OA Pubs

BACKGROUND: In Nigeria, approximately 150,000 children with sickle cell anemia (SCA) are born annually, accounting for more than half of all SCA births worldwide. Without intervention, about 11% of children with SCA will develop a stroke before their 20th birthday. Evidence-based practices for primary stroke prevention include screening for abnormal transcranial Doppler (TCD) measurements coupled with regular blood transfusion therapy for at least one year, followed by hydroxyurea (HU) therapy indefinitely. In high-resource countries, this strategy contributes to a 92% decrease in stroke incidence rates. In 2016, as part of a capacity building objective of the Stroke Prevention Trial in …

Programming Maintenance For The Mystery Student Intervention, Sarah Litten

Dissertations

The current study evaluated the effects of the Mystery Student Intervention (MSI) in university and community-based preschool settings on the appropriate and disruptive behaviors in the classroom utilizing a randomized independent group contingency. This study extended the literature base of the MSI, which was previously conducted in Head Start classrooms by Pasqua (2019), and Pasqua and colleagues (2021) which determined the MSI to be effective at reducing disruptive behaviors in the classroom setting. A nonconcurrent multiple baseline design across three classrooms was used. This study also sought to further extend the literature by evaluating programmed maintenance using a partial sequential …

Quantitative Relationships Between River And Channel-Belt Planform Patterns, Tian Y. Dong, Timothy A. Goudge

School of Earth, Environmental, & Marine Sciences Faculty Publications

Channel planform patterns arise from internal dynamics of sediment transport and fluid flow in rivers and are affected by external controls such as valley confinement. Understanding whether these channel patterns are preserved in the rock record has critical implications for our ability to constrain past environmental conditions. Rivers are preserved as channel belts, which are one of the most ubiquitous and accessible parts of the sedimentary record, yet the relationship between river and channel-belt planform patterns remains unquantified. We analyzed planform patterns of rivers and channel belts from 30 systems globally. Channel patterns were classified using a graph theory-based metric, …

Differential And Shared Genetic Effects On Kidney Function Between Diabetic And Non-Diabetic Individuals, Thomas W. Winkler, Humaira Rasheed, Alexander Teumer, Mathias Gorski, Bryce X. Rowan, Kira J. Stanzick, Laurent F. Thomas, Adrienne Tin, Anselm Hoppmann, Mikko Kuokkanen

School of Medicine Publications

Reduced glomerular filtration rate (GFR) can progress to kidney failure. Risk factors include genetics and diabetes mellitus (DM), but little is known about their interaction. We conducted genome-wide association meta-analyses for estimated GFR based on serum creatinine (eGFR), separately for individuals with or without DM (nDM = 178,691, nnoDM = 1,296,113). Our genome-wide searches identified (i) seven eGFR loci with significant DM/noDM-difference, (ii) four additional novel loci with suggestive difference and (iii) 28 further novel loci (including CUBN) by allowing for potential difference. GWAS on eGFR among DM individuals identified 2 known and 27 potentially responsible loci for diabetic …

The Development And Implementation Of A Computer Adaptive Progress Test Across European Countries, Neil Rice, José Miguel Pêgo, Carlos Fernando Collares, Jolanta Kisielewska, Thomas Gale

Peninsula Medical School

No abstract provided.

Liguoro V. Malone

All Decisions

No abstract provided.

Zev Ger Inc. V. Garcia

All Decisions

No abstract provided.

Use Of Networking Apps And Knowledge Sharing Among Librarians In University Of Port Harcourt, Humphrey I. Wiche (Ph D), Eruchi Brown Akpelu, Kelechi Keyna Ray-Ogbonna

Library Philosophy and Practice (e-journal)

The study investigated the use of networking applications for knowledge sharing among librarians in University of Port Harcourt, Rivers State. The purpose was to identify the types of networking apps used, the extent of use, perceived benefits, and problems associated with the use of networking apps for knowledge sharing. The study adopted a descriptive survey design. The population comprised the total of 25 librarians (both practicing & teaching staff). Structured Questionnaire was used as primary instrument for data collection. Data collected was analysed using descriptive statistics of arithmetic mean and standard deviation. The study however identifies email apps, whatsapp, facebook …

Variants In Asph Cause Exertional Heat Illness And Are Associated With Malignant Hyperthermia Susceptibility, Yukari Endo, Linda Groom, Alper Celik, Natalia Kraeva, Chang Seok Lee, Sung Yun Jung, Lois Gardner, Marie-Anne Shaw, Susan L Hamilton, Philip M Hopkins, Robert T Dirksen, Sheila Riazi, James J Dowling

Faculty, Staff and Students Publications

Exertional heat illness (EHI) and malignant hyperthermia (MH) are life threatening conditions associated with muscle breakdown in the setting of triggering factors including volatile anesthetics, exercise, and high environmental temperature. To identify new genetic variants that predispose to EHI and/or MH, we performed genomic sequencing on a cohort with EHI/MH and/or abnormal caffeine-halothane contracture test. In five individuals, we identified rare, pathogenic heterozygous variants in ASPH, a gene encoding junctin, a regulator of excitation-contraction coupling. We validated the pathogenicity of these variants using orthogonal pre-clinical models, CRISPR-edited C2C12 myotubes and transgenic zebrafish. In total, we demonstrate that ASPH variants represent …

Estimating Circadian Phase In Elementary School Children: Leveraging Advances In Physiologically Informed Models Of Circadian Entrainment And Wearable Devices, Jennette P Moreno, Kevin M Hannay, Olivia Walch, Hafza Dadabhoy, Jessica Christian, Maurice Puyau, Abeer El-Mubasher, Fida Bacha, Sarah R Grant, Rebekah Julie Park, Philip Cheng

Faculty, Staff and Students Publications

STUDY OBJECTIVES: Examine the ability of a physiologically based mathematical model of human circadian rhythms to predict circadian phase, as measured by salivary dim light melatonin onset (DLMO), in children compared to other proxy measurements of circadian phase (bedtime, sleep midpoint, and wake time).

METHODS: As part of an ongoing clinical trial, a sample of 29 elementary school children (mean age: 7.4 ± .97 years) completed 7 days of wrist actigraphy before a lab visit to assess DLMO. Hourly salivary melatonin samples were collected under dim light conditions (<5 >lx). Data from actigraphy were used to generate predictions of circadian …

Do Auditors Respond To Changes In Clients’ Analyst Coverage? Evidence From A Natural Experiment, Mohammad Alkhamees

USF Tampa Graduate Theses and Dissertations

Prior research has established that analysts serve as an important monitor of managementand improve the quality of firms’ financial reporting. In this study, I utilize the natural experiment resulting from the mergers and closures of brokerage houses, to examine whether this exogenous change in firms’ information environment impacts the audit process. Specifically, I examine whether reductions in analyst coverage have an effect on auditor effort proxied by audit fees and audit report lag, as well as financial reporting quality, measured by future restatements. I find that client firms pay significantly higher audit fees following an exogenous reduction in analyst coverage …

Climate And Intraspecific Geographic Variation Of Nests And Eggs In The Eastern Kingbird Tyrannus Tyrannus, Samantha Marie Gillette

Dissertations and Theses

The reproductive success of birds is ultimately driven by the traits of nests, eggs, and incubation behavior and the interactions among them. Avian reproduction varies on large geographic scales, most prominently between tropic- vs. temperate-breeding species, but also on finer scales, such as along latitudinal and elevational geographic gradients. However, despite the importance of eggs and nests, how their traits vary geographically in response to differences in regional climate remains understudied.

We studied Eastern Kingbirds (Tyrannus tyrannus), which have been previously demonstrated to alter incubation length in response to local climate conditions. Our study sites, Kansas (KS), New …

The Daughters Of The Fronde: French Aristocratic Women And The Subversion Of Bourbon Absolutist Culture, 1661-1727, Jordan David Hallmark

Dissertations and Theses

The turbulent events of the Fronde des Princes (Fronde of the Princes), which saw the French nobility stage a failed rebellion against the monarchical administration of France's chief minister, Cardinal Mazarin, between 1650 and 1652, have been portrayed in the existing historiography as the swan song of a pre-absolutist nobility seeking to preserve its feudal identity as the king's partner in governance and military affairs. Indeed, as many historians of early modern France have observed, the policies pursued by Cardinal Mazarin following the monarchy's victory over the rebel princes of the Fronde, and subsequently expanded upon by Louis XIV after …