Digital Commons Network^™

Concurrent Fnirs And Eeg For Brain Function Investigation: A Systematic, Methodology-Focused Review, Rihui Li, Dalin Yang, Feng Fang, Keum-Shik Hong, Allan L Reiss, Yingchun Zhang

2020-Current year OA Pubs

Electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) stand as state-of-the-art techniques for non-invasive functional neuroimaging. On a unimodal basis, EEG has poor spatial resolution while presenting high temporal resolution. In contrast, fNIRS offers better spatial resolution, though it is constrained by its poor temporal resolution. One important merit shared by the EEG and fNIRS is that both modalities have favorable portability and could be integrated into a compatible experimental setup, providing a compelling ground for the development of a multimodal fNIRS-EEG integration analysis approach. Despite a growing number of studies using concurrent fNIRS-EEG designs reported in recent years, the methodological …

Facilitators For Retaining Men Who Have Sex With Men In Pre-Exposure Prophylaxis Care In Real World Clinic Settings Within The United States, Brooke G Rogers, R R Patel, K Curoe, A Underwood, J Villalobos, Et Al.

2020-Current year OA Pubs

BACKGROUND: Pre-exposure prophylaxis (PrEP) can significantly reduce HIV acquisition especially among communities with high HIV prevalence, including men who have sex with men (MSM). Much research has been finding suboptimal PrEP persistence; however, few studies examine factors that enhance PrEP persistence in real-world settings.

METHODS: We interviewed 33 patients who identified as MSM at three different PrEP clinics in three regions of the U.S. (Northeast, South, Midwest). Participants were eligible if they took PrEP and had been retained in care for a minimum of 6 months. Interviews explored social, structural, clinic-level and behavioral factors that influencing PrEP persistence.

RESULTS: Through …

Discovery And Validation Of Dominantly Inherited Alzheimer's Disease Mutations In Populations From Latin America, Leonel Tadao Takada, Bhagyashri D Burgute, Ellen Ziegemeier, Jennifer Petranek, Carlos Cruchaga, Maria Victoria Fernández, Eric Mcdade, Randall J Bateman, Celeste M Karch, Jorge J Llibre-Guerra, Et Al.

2020-Current year OA Pubs

BACKGROUND: In fewer than 1% of patients, AD is caused by autosomal dominant mutations in either the presenilin 1 (PSEN1), presenilin 2 (PSEN2), or amyloid precursor protein (APP) genes. The full extent of familial AD and frequency of these variants remains understudied in Latin American (LatAm) countries. Due to the rare nature of these variants, determining the pathogenicity of a novel variant in these genes can be challenging. Here, we use a systematic approach to assign the likelihood of pathogenicity in variants from densely affected families in Latin American populations.

METHODS: Clinical data was collected from LatAm families at risk …

Developmental Trajectories Of Cortical Thickness By Functional Brain Network: The Roles Of Pubertal Timing And Socioeconomic Status, Ashley F. P. Sanders, Graham L. Baum, Michael P. Harms, Sridhar Kandala, Susan Y. Bookheimer, Mirella Dapretto, Leah H. Somerville, Kathleen M. Thomas, David C. Van Essen, Essa Yacoub, Deanna M Barch

2020-Current year OA Pubs

The human cerebral cortex undergoes considerable changes during development, with cortical maturation patterns reflecting regional heterogeneity that generally progresses in a posterior-to-anterior fashion. However, the organizing principles that govern cortical development remain unclear. In the current study, we characterized age-related differences in cortical thickness (CT) as a function of sex, pubertal timing, and two dissociable indices of socioeconomic status (i.e., income-to-needs and maternal education) in the context of functional brain network organization, using a cross-sectional sample (n = 789) diverse in race, ethnicity, and socioeconomic status from the Lifespan Human Connectome Project in Development (HCP-D). We found that CT generally …

Safety And Tolerability Of Carboplatin And Paclitaxel In Cancer Patients With Hiv (Amc-078), An Aids Malignancy Consortium (Amc) Study, Missak Haigentz, Page Moore, Milan Bimali, Timothy Cooley, Joseph Sparano, Michelle Rudek, Lee Ratner, David Henry, Juan Ramos, John Deeken, Paul Rubinstein, Elizabeth Chiao

2020-Current year OA Pubs

BACKGROUND: Persons living with human immunodeficiency virus are an underserved population for evidence-based cancer treatment. Paclitaxel and carboplatin (PCb) is an active regimen against a variety of solid tumors, including several seen in excess in patients with HIV infection. We performed a pilot trial to evaluate the safety of full-dose PCb in people living with human immunodeficiency virus and cancer.

METHODS: Eligible patients, stratified by concurrent antiretroviral therapy (ART) that included CYP3A4 inhibitors or not, received paclitaxel (175 mg/m2) in combination with carboplatin (target AUC 6) intravenously every 3 weeks for up to 6 cycles.

RESULTS: Sixteen evaluable patients received …

Proportional Component Order Network Connectivity, Nicholas Hanson, Nathan Shank, Ashley Armbruster, Jiequi Di

Communications on Number Theory and Combinatorial Theory

We introduce a new measure of network reliability related to the order of the largest component. This new connectivity measure considers a network to be operational if there is a component or order at least some fixed proportion, r, of the original order. Thus, the network is in a failure state if all components are sufficiently small. In this paper, we consider the parameters with vertex deletions as well as edge deletions for particular graph classes. We also find the minimum values of the parameter for graphs with a fixed size and order. We end with a discussion and some …

Exploring The Use Of A Restoration Step To Detect Mosaic Chromosomal Alterations In Prostate Samples, Ayanna N. Woodberry, Justin W. Wong, Paul A. Scheet

Summer Experience 2022

Department of Epidemiology

Efficacy Of A 6-Week Suspension Training Exercise Program On Fitness Components In Older Adults, Christina Pierle, Alexander T. Mcdaniel, Lindsey H. Schroeder, Michel J.H. Heijnen, Wayland Tseh

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1168-1178, 2022. The purpose of this study was to determine the efficacy of a 6-week suspension training exercise program on fitness components in older adults. Eleven participants (age = 80 ± 5 yrs) completed a 6-week suspension training exercise program. Pre- and post-fitness assessments comprised of body composition, handgrip dynamometer, functional reach, and balance. The 6-week suspension training intervention required individuals to perform suspension training exercises for fifty minutes, twice per week. A paired sample t-test was used to determine differences from pre-and post-assessments. An improvement was observed in functional reach (57.2 ± …

The Association Between Handgrip Strength Asymmetry Severity And Future Morbidity Accumulation: Results From The Health And Retirement Study, Lukus Klawitter, Kyle Collins, Dawson Ringhofer, Bryan Christensen, Ryan Mcgrath

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1133-1141, 2022. Analyzing the severity of handgrip strength (HGS) asymmetry in aging populations may help to screen for morbidities and add utility to handgrip dynamometer testing. Our study sought to determine the relationships between HGS asymmetry severity and future accumulating morbidities in older Americans. Secondary analyses from the 2006-2016 waves of the Health and Retirement Study included 18,506 adults ≥ 50 years old. The highest recorded HGS values from each hand were used to calculate HGS asymmetry ratio (non-dominant HGS/dominant HGS). If the HGS asymmetry ratio < 1.0, it was inversed to make all asymmetry ratios ≥ 1.0. Participants were categorized into groups based on the severity of their HGS asymmetry ratio: 1) 0.0% - 10.0%, 2) 10.1% - 20.0%, 3) 20.1% - 30.0%, and 4) > 30.0%. Healthcare provider-diagnosed morbidities (hypertension, diabetes, cancer, chronic …

Impact Of Acute Uninterrupted Sitting On Cerebrovascular Hemodynamics, Raymond Jones, Dominique Mcarthur, Stephanie Mccoy, Lee Stoner, Simon Fryer, Daniel P. Credeur

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 1156-1167, 2022. Reductions in brain blood flow are associated with reduced cognitive function and cerebrovascular disease. Acute periods of uninterrupted sitting can lead to endothelial dysfunction, namely due to a reduction in shear stress and subsequent reduction in nitric oxide bioavailability. Little is known of the impact of sitting on brain health. The purpose was to determine the total brain blood flow response following a 60-minute bout of uninterrupted sitting. Using a parallel design, this study evaluated the impact of 60-minutes of sitting on total brain blood flow. Fifteen participants (n=15; age=24 ± …

Effects Of Creatine Supplementation And Progressive Resistance Training In Stroke Survivors, Sara Butchart, Darren G. Candow, Scott Forbes, Cameron Mang, Julianne Gordon, Jongbum Ko, Dalton Deprez, Phil Chilibeck, David Ditor

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 1117-1132, 2022. The purpose was to investigate the effects of progressive resistance training (PRT) and creatine supplementation in stroke survivors. Participants were randomized to one of two groups: creatine (n = 5; 51 ± 16y) or placebo (n = 3; 73 ± 8y) during 10 weeks of supervised PRT. Prior to and following PRT and supplementation, assessments were made for body composition (lean tissue and fat mass), muscle thickness, muscle strength (1-repetition maximum), functional exercise capacity (6-minute walk test, Berg Balance Scale; BBS), cognition (Montreal Cognitive Assessment; MoCA), and symptoms of anxiety …

Muscle Activation Patterns Of The Proximal Medial And Distal Biceps Femoris And Gluteus Maximus Among 6 Hip Extension And Knee Flexion Exercises In Trained Women., Bryn M. Stevens, Ben R. Nichols, Holly I. Doty, John Adam Korak

International Journal of Exercise Science

International Journal of Exercise Science 15(1): 1179-1189, 2022. The biceps femoris (BF) is a double-jointed muscle that performs both hip extension and knee flexion, making it a challenging muscle to train during common resistance training movements. An imbalance between the posterior and anterior chain increases the risk of lower-extremity injury. The purpose of this study was to compare BF proximal (BFprox), BF medial (BFmed), and BF distal (BFdist) peak and mean muscle activation among four hip hinging movements and two knee flexion movements. A secondary variable was gluteus maximus (GMax) muscle activation among the same six movements. Fifteen trained females …

Freely Chosen Cadence Is Increased During Repeated Bouts Of Submaximal Ergometer Pedalling, Andreas Schmidt, Jonas G. Madsen, Magnus K. Hyttel, Ernst A. Hansen

International Journal of Exercise Science

International Journal of Exercise Science 15(1): 1142-1155, 2022. It was investigated whether the phenomenon of repeated bout rate enhancement occurs during submaximal ergometer cycling. Repeated bout rate enhancement is defined as an increase of the freely, or spontaneously, chosen cadence during repeated bouts of pedalling and has previously been reported for finger tapping. This is relevant to study since cadence can affect biomechanical and physiological responses. Recreationally active individuals (n=27) performed five consecutive 5-min bouts of cycling at 100 W using freely chosen cadence. All bouts were separated by 10-min rest. Cadence, pedal force profile characteristics, heart rate, …

Isaac Collins House/Farm: Maps And Drawings

Documentation

Eight Figures of Isaac Collins/ Plain Pond Farm from Wilbur Smith and Associates: Topographic Location Map, Location Plats, Farm Complex/Field System, Floor Plan - First Floor, Floor Plan - Second Floor, Major Outbuildings, Isaac Collins Ice House Site, Isaac Collins Historic Cemetery.

Enhancing Anti-Tumor Immunity Through High-Let Radiation And Immunotherapy, Sachita Guthula, David Martinus, Scott J. Bright, Simona Shaitelman, Gabriel Sawakuchi

Summer Experience 2022

No abstract provided.

Liberty And Responsibilty In Religion, Earl Clement Davis

Sermons, 1905-1919

In some cases, Earl Davis bound together manuscripts in bundles. This manuscript is part of one such bundle of seven, held together by four brass fasteners. Six of the seven can be dated to 1918.

This is another in a series of reflections regarding the meaning of World War I and the change it will prompt. Davis regards Christianity as a way of living while alive, not as a counsel to count on the second coming. He states that though we have given up the idea of a "ready-made Heaven" coming down to earth from above, this false idea …

Exploring The Electronic Course Reserves Management And Reading List Tool Leganto Through The Lenses Of Academic Librarians And Instructors, Wei Zakharov, Thom Gerrish, Haiyan Li, Alison L. Davis, Emily Little

Distance Library Services Conference

No abstract provided.

Deconstructing Gendered Vumilia (Perseverance) Theology In Times Of The Gender-Based Violence Pandemic, Esther Mombo, Heleen Joziasse

Journal of International Women's Studies

During the COVID-19 pandemic, cases of gender-based violence (GBV) dramatically increased. While the Kenyan governmental bodies are held responsible for their inadequate response to this “national disaster of GBV”, the role of the Kenyan churches is hardly criticized. The churches neither spoke out against this prevalent injustice, nor did they openly support the victims of GBV. Furthermore, it could be argued that churches, through their patriarchal structures and cultural and doctrinal teachings, have contributed to this disaster. This article is written from a woman’s perspective and focused on the notion of vumilia, or perseverance, an important notion in the lived …

Discourse(S) Of Identity: Precarity And (In)Visibility In Farida Karodia’S Daughters Of The Twilight, Goutam Karmakar, Rajendra Chetty

Journal of International Women's Studies

Apartheid South Africa witnessed the forming of cultural and sexual identities within political strategies that were designed to categorize and regulate “non-white” individuals. By dealing with interactions between white men and black women, South African literary works in the penultimate years of apartheid demonstrate apartheid’s structural viciousness and gendered hierarchy through certain innovative deviations. Daughters of the Twilight (1986) by Farida Karodia is one such text that not only sheds light on the masculine, racialized, and patriarchal apartheid structure of the male gaze, but also inherently disallows the female characters of Karodia’s narrative to inhabit neither day nor night, as …

African Moral Fibre As The Lost Glory In Combating Violence Against Women, Lilian Cheelo Siwila

Journal of International Women's Studies

Africa, like any other society, embodies moral responsibilities that govern the way society is to be ruled. These morals, which are embedded in people’s belief systems and worldviews, are transmitted from generation to generation. The gendered nature of these morals can be reflected in the way women and girls are protected and respected in their communities. Since the holistic mothering roles of women are viewed as the highest order of society, heinous crimes like violating a woman are seen as taboo in that society. Among the Tonga people of Zambia, where this study is located, raping or beating a woman …

Ndwae Ngone Mwaitu: A Postmodern Cultural Phenomenon Of Dowry Among The Akamba And Its Influence On Spousal Violence, Telesia Kathini Musili

Journal of International Women's Studies

Dowry, also referred to as bride wealth or bride price, is a consultative, amicable, and quantifiable summation of goods exchanged between the groom’s and bride’s families. Traditionally, dowry (ngasya) payment among the Akamba was an obligation for the parents-in-law (husband’s parents), but that has in the recent past transitioned to the husband paying the dowry himself. An emerging trend is, however, catching up with married women budding together and opting to pay the dowry for themselves, which is not only a cultural shock and an empowering paradigm shift but also a ceremony that could be riddled and clouded …

Formation Of Positive Organizational Climate: Integration Of Ubuntu Diversity Management In Banks, Surjit Singha, R Sivarethinamohan

Journal of International Women's Studies

No abstract provided.

Physical Abuse In The Absence Of Ubuntu, Ranjit Singha, Yogesh S. Kanna

Journal of International Women's Studies

Students in Africa and worldwide should learn about Ubuntu at the school, secondary school, college, and university levels. It should be incorporated into the educational process. Tobacco-free days, alcohol-free (dry days), and drug-free days could all be ways to commemorate Ubuntu. Female smokers are at a higher risk than male smokers. Following such measures may aid in raising awareness. Legislators in Africa need to employ incentives to amend legislation to fully integrate Ubuntu into society. It is possible to prevent violence against women and children by instilling Ubuntu principles in the community and society. It is sufficient to refer to …

Vatsonga Cultural Practices And Their Impact On The Health Of Widows And Significant Others, Fanisa Baloyi, Jabulani Owen Nene, Azwihangwisi Helen Mavhandu-Mudzusi

Journal of International Women's Studies

This paper presents the Vatsonga cultural practices regarding widowhood and how those practices impact personal health. The purpose of the study was to gain an in-depth understanding of how the Vatsonga manages widowhood and how those practices affect the management of HIV/AIDS. This ethnographic study was conducted in Bushbuckridge and is grounded in Leininger’s theory of Culture Care Diversity and Universality. Data was collected from participants using individual face-to-face interviews and observation. In addition, ethnographic content analysis was utilized for data analysis. Results indicate that there are practices such as widow cleansing and widow inheritance that the Vatsonga people practice …

The Angst Of The Dehumanized: Ubuntu For Solidarity, Lillykutty Abraham, Krishna V. P. Prabha

Journal of International Women's Studies

This article attempts to delve into the multiple forms of violence experienced by South African women, within the theoretical framework of the ecological model of abuse proposed by Lori L. Heise (1998). The objective of the article is to explore how the communitarian dimension of ubuntu is absent when the womenfolk is in question. Their existence itself appears to be insignificant compared to their counterparts. Ubuntu cannot be lived or practiced while some are excluded from this concept. Gender inequality and inequitable status of existence cannot be part of ubuntu, as “I am, because you are” or the meaning …

Women, Security, And Gender-Based Violence In The Northeast, Nigeria, Abidemi Abiola Isola, Adeogun Tolulope

Journal of International Women's Studies

Gender-based violence is inevitable in every armed conflict zone. To survive, every human being, including women and girls, requires security. In armed conflict zones, however, women and girls are more vulnerable to the dangers of insecurity. These difficulties may influence them physically, psychologically, economically, and educationally. They may also have to live with the effects of their trauma for the rest of their lives. The effects of the Boko Haram insurgency on women’s security in Nigeria’s northeast are the subject of this study. This investigation relied on structural violence theory. It’s a meta-analytical study based on secondary sources like books, …

Stitching Narratives Of Gender-Based Violence: Meaning-Making Through Embroidery, Puleng Segalo

Journal of International Women's Studies

COVID-19 has altered how we engage with one another. With social distancing as the new norm, and the prolonged lockdown having affected people at various levels of their lives, life has had to be reimagined and reconfigured. One of the things that has remained stable, if not worsened, is the challenge of gender-based violence. In South Africa and many other countries in the world, when strict lockdown rules were introduced, Gender-Based Violence (GBV) started making headlines on many media platforms, sparking protests, online dialogues, and online support networks for those affected. While people were worried about protecting themselves against COVID-19, …

Affirming The Traditional Teaching Of Imbusa As A Tool Against Gender-Based Violence, Sylvia Mukuka

Journal of International Women's Studies

The main objective of this paper is to provide light on the traditional teaching of Imbusa, which is utilized to combat the problem of gender-based violence. Violence against women has increased to incredible rates in modern societies, to the point where many women continue to perpetuate anguish in the form of physical abuse, assaults, and molestation, and all these social evils have left women badly devastated, scared, disoriented, and defenceless. Violence entails the use of physical force, such as sexual assault, to injure, mutilate, or kill humans, and occasionally to ruin an individual's life. This paper examines several forms of …

Covid-19 And Ubuntu Disruptions: Curbing The Violence Against Women And Girls With Disabilities Through African Women’S Theology Of Disability, Sinenhlanhla S. Chisale

Journal of International Women's Studies

The COVID-19 restrictions that require the lockdown of public and economic activities heighten the levels of sexual and gender-based violence against women and girls with disabilities. As the COVID-19 pandemic spreads across the globe, particularly in Africa, women and girls with disabilities become vulnerable to sexual and gender-based violence, highlighting that the home is no longer a safe space for the vulnerable. The restrictions have eroded the community structures that are promoted by Ubuntu to protect vulnerable community members from violence and different forms of abuse. This article grapples with the question of African women’s theology of disability and Ubuntu …

Depiction Of Women’S Oppression And Gender-Based Domestic Violence Against Girls In Tsitsi Dangarembga’S Nervous Conditions, Benon Tugume

Journal of International Women's Studies

This article examines women’s oppression and gender-based domestic violence against girls in Tsitsi Dangarembga’s Nervous Conditions (1988). The novel is set between two families in the Shona community of Zimbabwe. The focus is on women’s entrapment in the institution of marriage and gender-based violence inflicted on girls by male patriarchs to force them to bow down to patriarchal authority. Tambudzai, the main narrator and protagonist tells a story of how her mother, Ma’ Shingayi (a peasant housewife), and her uncle’s wife, Maiguru, (a teacher with a Master’s degree) get entrapped in the marriage institution where they have no voice, how …