Digital Commons Network^™

Hybrid Cnn–Gru-Based Demand–Supply Forecasting To Enhance Sustainability In Renewable-Integrated Smart Grids, Süleyman Emre Eyimaya, Necmi Altin

Faculty Publications

The rapid integration of renewable energy sources in smart grids has introduced significant uncertainty in both power generation and consumption patterns, posing challenges to environmental, economic, and operational sustainability. Accurate short-term forecasting of energy demand and supply is essential for achieving optimal scheduling, grid stability, and resilient operation in renewable-integrated power systems. This study proposes a hybrid deep learning framework combining Convolutional Neural Networks (CNN) and Gated Recurrent Units (GRU) for intelligent joint demand–supply forecasting in smart grids. The model was developed and implemented in MATLAB using real-world datasets comprising electricity consumption, photovoltaic (PV) generation, temperature, and irradiance variables. Comparative …

Ndls Communicator: Week Of 03.02.26, Notre Dame Law School

NDLS Communicator

The Latest News

• Notre Dame Exoneration Justice Clinic Client Reginald “Reggie” Dillard Exonerated After 27 Years of Wrongful Imprisonment

Student News

• William Branson Donahue
• Dennis Wieboldt
• Perla Khattar
• Nicolás Buitrago-Rey

Faculty Briefs

• Carter Snead
• Diane Desierto
• Mary Ellen O'Connell
• Francisco Urbina
• Rick Garnett
• David McIlroy
• Paolo Carozza
• Ashley Sanchez

ND Law in the News

• Several outlets highlighted the Notre Dame Law School Exoneration Justice Clinic’s work in the exoneration of clinic client Reggie Dillard.

Events

• Law & Technology Seminar: Raúl Madrid, Professor of Law and Director of the Program on Law, Science, and Technology at the Pontificia Universidad Católica de …

Regulating Ai In Pediatrics-Is Transparency Enough?, R Brandon Hunter, Kolaleh Eskandanian, Chester J Koh

Faculty, Staff and Students Publications

No abstract provided.

Activin A Secretion By Muscle-Repairing Macrophages Induces Heterotopic Ossification In Mice, Wenqiang Yin, Kazuo Okamoto, Asuka Terashima, Warunee Pluemsakunthai, Takehito Ono, Taku Ito-Kureha, Shizuo Akira, Yoshinobu Hashizume, Roland Baron, Satoshi Ueha, Kouji Matsushima, Martin M Matzuk, Yuji Mishina, Hiroshi Takayanagi

Faculty, Staff and Students Publications

The immune system is not only essential for host defense, but it is also involved in tissue maintenance and disease pathogenesis. Macrophages play a key role in tissue repair, fibrosis, and tumorigenesis, but the mechanisms underlying their multifunctionality have not been fully explored. Here, we identified Mrep (Ly6ChiCX3CR1loPDPN+CD9+) as a crucial subset of macrophages for muscle regeneration after muscle injury. Muscle regeneration required Mrep-derived activin A, which was produced via the TLR4/TIR domain-containing adapter-inducing interferon-β/TANK-binding kinase 1/interferon regulatory factor 3/7 signaling pathway in response to muscle injury. Mrep exerted pathological effects by secreting activin A in a model of genetically …

Designing Novel Bisquinoline Antimalarials From Historical 4-Aminoquinolines To Combat Drug-Resistant Malaria, Mason J. Handford, Yuexin Li, Terry Riscoe, Xiaowei Zhang, Jane X. Kelly, Michael K. Riscoe

Chemistry Faculty Publications and Presentations

Plasmodium falciparum, the deadliest causative agent of malaria, continues to evade eradication efforts through widespread drug resistance. The recent development of ADC-028, a 4-aminoquinoline antimalarial with excellent activity and pharmacokinetic properties, prompted the investigation of bisquinoline analogs featuring similar structural motifs. Here, we describe a structure-activity relationship study that guided the optimization of compounds with key features, including the 4-anilinoquinoline core and diverse bridging linkers. Several analogs exhibited potent in vitro activity (IC50 < 20 nM) against both drug-sensitive and multidrug-resistant P. falciparum strains, while maintaining favorable cytotoxicity profiles. Among them, 25 demonstrated improved intrinsic metabolic stability (t1/2 = 121 min) and potent in vivo efficacy (ED50 = 0.32 mg/kg/day), achieving complete curative protection at a reduced dose compared to ADC-028. While 25 showed moderately reduced oral bioavailability (F = 43%) and a shorter half-life (T1/2 = 27.2 h) relative to ADC-028, its enhanced in vivo efficacy underscores its therapeutic potential. This work highlights a promising path forward in developing antimalarials that retain the efficacy of legacy compounds while overcoming modern resistance mechanisms.

Which Repair Technique, Bone Tunneling Or Suture Anchors, Is Superior When Performing Lesser Tuberosity Osteotomy At The Time Of Stemless Total Shoulder Arthroplasty?, Jared M. Mahylis, Stephaine J. Muh, Mahdi Mazeh, Emil Espinal Nunez, Daniel Oravec, Johnny Kasto, Chimdindu Obinero, Kai Zhu, Yener N. Yeni, Shariff K. Bishai

Conference Presentation Abstracts

INTRODUCTION: Total shoulder arthroplasty (TSA) has evolved as a treatment for advanced shoulder osteoarthrosis, with stemless implants gaining popularity due to reduced risks of stress shielding and complications associated with stemmed designs. However, the optimal technique for repairing the subscapularis during TSA remains under investigation. This study evaluates the biomechanical performance of two repair techniques—bone tunneling and suture anchors—used for Lesser Tuberosity Osteotomy (LTO) in the context of stemless TSA.  
METHODS: Ten shoulders from six cadaveric specimens (3 male, 3 female; aged 58–93) were prepared and allocated to bone tunneling or suture anchor repair groups. Cyclic loading tests were performed, …

Medial Meniscus Root Repair Demonstrates Superior Radiographic And Clinical Outcomes At Long-Term Follow-Up Compared To Partial Medial Meniscetomy, Robert Dean, Ryan Mcnassor, Aaron John Krych, Brian R. Waterman

Conference Presentation Abstracts

INTRODUCTION: Posterior medial meniscus root tears (PMMRTs) are frequently observed injuries that lead to alterations in tibiofemoral biomechanics. Few long-term reviews have considered the long term clinical and radiographic outcomes of management of these injuries. This study sought to perform a systematic review and meta-analysis of the current literature on long term clinical and radiographic outcomes of PMMRTs. METHODS: Using PRISMA guidelines, a systematic review was performed with inclusion criteria of English language studies, diagnosis of PMMRT on MRI with confirmation on arthroscopy if managed operatively, studies with minimum 5-year radiographic or patient reported outcome metrics. Data including management strategy, …

Editorial: Clinical Imaging, Neurophysiological, Neuropathology And Neuroethics Studies On Disorders Of Consciousness, Coma Mechanisms, And Theories Of Consciousness: A Unifying Attempt, Diego Iacono, Manuel Trachsel, Thanh Phan, Charlène Aubinet

Department of Neurology Faculty Papers

No abstract provided.

Selassie Atoklo V. Attorney General United States Of America

2026 Decisions

Agency

The Trump Administration’S Theory Of Constitutional War Powers: “The President Could Decide”, Rebecca Ingber

Online Publications

President Donald Trump has launched another unlawful war, this time in the service of regime change in Iran. The administration has been threatening the use of force for weeks, but provided very little public justification, description of what the president hoped to accomplish, or explanation for how the use of force would effectuate such goals. It has also to date presented no legal justification whatsoever. Much of what we know at this moment about how the administration views, and how it lawyers, questions of war powers can be derived from the one legal memorandum the administration has released on the …

Usa V. Albert Boufarah

2026 Decisions

USDC for the District of New Jersey

Chimes: March 2, 2026, Calviin University

Chimes

Next phase of stadium construction marks a "game changer" for Calvin Athletics by Sarah Sparling

Morren Fitness Center's $100,000 upgrade receives mixed reactions by Sarah Sparling

"Stories of Communicating Scientific Ocean Drilling, From Text to Textiles": An exploration of science communication by Maya Oeverman

Christine Jeske on racial justice, rugged hope and enduring change by Ashley Hamons

IFI: A home for international students in West Michigan by Evangeline Anga

Men's basketball season ends in semifinals of MIAA tournament by Zach Kern & Henrik Beelen

Calvin Writers Read: A collective experience of art by Jorie Cho

Everyday Resistance: A journey in …

Political Mediatization In The Digital Era: The Case Of Walhi West Sumatera’S Environmental Advocacy, Muhammad Thaufan Arifuddin, Ernita Arif, Yuliandre Darwis, Rinaldi Rinaldi, Muhammad Al-Amin Dalmenda

JURNAL KOMUNIKASI INDONESIA

This article examines how political mediatization operates at the local level through environmental civil society activism in post-authoritarian Indonesia. Focusing on the West Sumatra chapter of the Indonesia Forum for Environment (WALHI) as a critical case, the study argues that media logic is not merely imposed by political elites or mainstream media, but is strategically appropriated by local civil society organizations to contest oligarchic power, shape public agendas, and sustain democratic engagement at the subnational level. Using a qualitative case study approach, data were collected through participant observation, in-depth interviews with environmental activists and youth organizers, and an analysis of …

The Diversity Band Presented By The Music Student Multicultural Association: March 2nd, 2026, Illinois State University School Of Music

School of Music Programs

This is the one hundred and fifteenth program of the 2025-2026 season.

Kemp Recital Hall

March 2nd, 2026

Monday Evening

7:30 p.m.

Colocalization And Functional Analyses Identify Gbe1 As A Gene Linking Muscle Strength And Cardiometabolic Fitness, Theresia M. Schnurr, Miranda L. Johnson, Christopher Jin, Kimmie V. Sørensen, Lindsey Kim, James W. Jahng, Amanda Ramste, Ewa Bielczyk-Maczynska, Michael J. Gloudemans, Peter Saliba-Gustafsson, Elena Vinton, Patrick L. Jurney, Ivan Carcamo-Orive, Euan A. Ashley, Torben Hansen, Joshua W. Knowles, Brian T. Palmisano

Faculty Research, Scholarly, and Creative Activity

Handgrip strength is a proxy for muscular fitness, an indicator for general health status, and is associated with cardiometabolic health. The mechanisms connecting handgrip strength to skeletal muscle function are incompletely understood. We applied integrated linkage-disequilibrium-adjusted colocalization analysis of genome-wide association study summary statistics for handgrip strength, combined with expression and splicing quantitative trait loci from skeletal muscle, and identified glycogen branching enzyme 1 (GBE1) as a candidate gene for handgrip strength. CRISPR-interference knockdown of GBE1 in immortalized human skeletal muscle cells (HMCL-7304) demonstrated decreased glycogen content and accumulation of polyglucosan bodies. Knockdown of GBE1 led to increased oxygen consumption …

A 2030 Energy Transition Pathway For Bishkek, Kyrgyz Republic, Kasiet Nurlanbekova

University Honors Theses

Bishkek remains heavily dependent on thermal generation to meet winter electricity and heating demand, while seasonal air pollution and growing urban energy demand continue to place pressure on aging infrastructure. Although Kyrgyzstan has adopted renewable energy targets, implementation remains limited, and winter reliability in the capital continues to depend on centralized combined heat and power generation.

This study evaluates whether Bishkek can improve its seasonal electricity adequacy by 2030 through alternative supply portfolios built around currently planned projects and moderate renewable additions. Using a seasonal portfolio model, the baseline and scenario 1 are compared. The baseline includes CHP-1 modernization, CHP-2, …

An Innovative Program: R3 Renewal, Resilience And Retention For Nursing Practice Starts In Nursing Education, Cynda Hylton Rushton, Vickie Hughes, Krysia Warren Hudson, Sandra Swoboda, Erin Wright, Nancy Reller, Ginger Hanson, Rita F. D'Aoust

Creating Healthy Work Environments (CHWE)

Burnout due to workload and work-life imbalance is reducing nursing capacity in Maryland and nationally. Faculty and staff burnout rate is 40% and new graduate nurse turnover rate is 19%. The R³: Renewal, Resilience and Retention Initiative (R³) is an educational initiative to build nurses' resilience and increase their well-being that will help sustain the workforce and bridge the gap between education and practice. Many sound initiatives have addressed this shortage which primarily focus on pipeline entry by increasing (a) enrollment in nursing programs and (b) the number of nursing faculty. Fewer initiatives have targeted …

Depression Due To Combined Dexamethasone And Cyproheptadine Abuse For Weight Gain, Sanjana Sateesh, Jatin Kumar, Dhananjay Ardawatia, Kishor M, Shashidhara Kc, Srikanth Ms

Digital Journal of Clinical Medicine

Cyproheptadine, an H1 antihistamine, and Dexamethasone, a long-acting steroid, are often misused in combination for addressing self-perceived body image issues and have become a popular but dangerous ‘weight gain cocktail’, often available over the counter without any prescription. This case describes a 25-year-old man who had self-prescribed the above-mentioned drugs in combination to address his self-perceived lean physique. This resulted in a significant weight gain, followed by an abnormal increase in appetite, which affected his daily life. Upon cessation, it resulted in rebound weight changes, depressive features, along with features of corticosteroid withdrawal, which required multidisciplinary management.

This case highlights …

Cultivation Of Arthrospira Platensis (Spirulina) In Food-Based Industrial Wastewater For High-Yield Phycocyanin Extraction, Pavithira Sathinathan

Student Works (2020-2029)

Arthrospira platensis (Spirulina) is a filamentous cyanobacterium valued for its nutritional profile, particularly the pigment–protein phycocyanin, with potent antioxidant and anti-inflammatory properties. Despite its industrial significance, large-scale commercialization remains constrained by high cultivation costs and inefficient extraction methods. This study investigated the use of food-based industrial wastewater as an alternative nutrient medium for Spirulina cultivation, aiming to reduce production costs, enhance phycocyanin yield, and support sustainable wastewater remediation. Three types of food-based wastewater with different nutrient composition (WW1, WW2, WW3) was diluted with Kosaric medium (1:1) and used for Spirulina cultivation. The highest biomass concentration was achieved in WW2 (1.93 …

Brief Of Copyright Scholars As Amici Curae In Support Of Respondent In Emmerich Newspapers, Inc. V. Particle Media, Inc., Jess Miers, Mark A. Lemley, Rebecca Tushnet

Akron Law Faculty Publications

The server test has served us well for nearly two decades. It matches the language of the statute, the well-settled distinction between direct and secondary liability, and the nature of the technology. The copyright owner here makes the work available freely to every site visitor, and may stop embedding with a few clicks on the keyboard. There is no need to strain the law of direct liability to protect any legitimate interests it might have.

This Court should decline the invitation to create a circuit split that would upset settled expectations and turn millions of online posters into infringers overnight.

Isde Guidelines On The Management Of Ct2n0 Esophageal Cancer, Sarbajit Mukherjee

All Publications

Esophageal cancer incidence is rising globally, with at least 500,000 new cases diagnosed annually. Management options for non-metastatic disease include primary resection, neoadjuvant or perioperative therapies, or definitive non-surgical treatment, with the choice being guided by tumor staging, histology, patient fitness, and available resources. However, even with the use of advanced diagnostic modalities, preoperative clinical staging is challenging with respect to accuracy of both tumor and nodal assessment. Early-stage esophageal cancer may be managed with local therapies, such as endoscopic mucosal resection or submucosal dissection, while for more advanced tumors managed with curative intent neoadjuvant oncologic therapy is commonly recommended. …

Biomechanical Characterization Of Porcine Lower Limb Arteries For Preclinical Evaluation Of Peripheral Vascular Devices, Barbara Batista De Oliveira, Frazer Heinis, Anastasia Desyatova, Jason Mactaggart, Alexey Kamenskiy

Journal Articles

Purpose Peripheral artery disease (PAD) predominantly affects the lower extremities, where complex biomechanical deformations during limb flexion contribute to disease progression and treatment failure. While human and cadaver studies have characterized these deformations, preclinical device testing requires large-animal models that replicate human arterial anatomy and biomechanics. Swine are commonly used, yet their biomechanical comparability to humans remains poorly defined. Methods We performed a detailed morphometric and biomechanical analysis of the external iliac (EIA), superficial femoral (SFA), and popliteal (PA) arteries in 20 Yucatan and 16 domestic swine using computed tomography angiography. Arteries were evaluated in straight and flexed limb postures …

An Ai Approach To Differentiating Lung Squamous Cell Carcinoma From Metastases Of Other Origins, Mark G Evans, Jennifer Ribeiro, Todd Maney, Anthony Helmstetter, Jennifer Johnson, Anthony Karnezis, Casey Bales, George Sledge, David Spetzler, Ari Vanderwalde, Matthew Oberley, Balazs Halmos, Hossein Borghaei, Farah Abdulla, David Bryant, Fred Hirsch, Hassan Ghani

Department of Medical Oncology Faculty Papers

IMPORTANCE: Distinguishing primary lung squamous cell carcinoma (SCC) from squamous metastases to the lung is a clinical challenge due to histopathologic similarities. Accurate diagnosis is essential to guide treatment decisions.

OBJECTIVE: To assess the utility of an artificial intelligence (AI) approach that includes evaluation of key orthogonal evidence in distinguishing primary lung SCCs from metastatic tumors of other tissue origins.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used GPSai, a tissue-of-origin AI model run automatically on each sample submitted for molecular profiling, to flag potential misdiagnoses among research-eligible cases submitted as lung SCC. Molecularly profiled cases within the Caris Life …

Population Analysis And Immunologic Landscape Of Melanoma In People Living With Hiv, Lindsay Barger, Derek Wang, Ashley Saravia, Valeria Mezzano, Gyles Ward, Cynthia Loomis, Carly Feldman, Madalina Tuluc, Rino Seedor, Peter Gaskill, Anna Coghill, Gita Suneja, Iman Dehzangi, Jennifer Hope, George Jour, Gabriele Romano

Department of Medical Oncology Faculty Papers

PURPOSE: To dissect the clinical and immunologic features of people living with human immunodeficiency virus (HIV; PLWH) diagnosed with melanoma, who have consistently shown worse outcomes than HIV-negative individuals (PLw/oH) with the same cancer.

EXPERIMENTAL DESIGN: We analyzed electronic health records from 1,087 PLWH and 394,437 PLw/oH with melanoma. Demographic and clinical characteristics were compared. Spatial immune transcriptomics (72 immune-related genes) was performed on melanoma tumor samples (n = 11), with downstream validation using multiplex immunofluorescence (mIF; n = 15 PLWH, n = 14 PLw/oH).

RESULTS: PLWH were diagnosed at a younger age, had a greater representation of Hispanic and …

Shifts In Antipsychotic Prescribing By Clinician Type For Medicare Part D Beneficiaries, 2013-2023, Youngran Kim, Xuan Zhou, Shilei Du, Trudy M Krause, Rafael Samper-Ternent, Antonio L Teixeira

Faculty, Staff and Student Publications

Importance: Despite safety warnings, antipsychotics remain commonly prescribed to older adults, particularly those with dementia, and for off-label indications. However, little is known about how prescribing patterns vary by clinician type over time.

Objective: To examine trends in antipsychotic prescribing by clinician type among Medicare beneficiaries from 2013 to 2023.

Design, setting, and participants: This repeated cross-sectional study used the Medicare Part D Prescribers by Provider and Drug dataset from 2013 to 2023. Participants included Medicare beneficiaries enrolled in Medicare Part D. Analyses were performed between November 2024 and June 2025.

Exposure: Prescribing clinician type, categorized as psychiatrist, primary care …

R. S. V. East Brunswick Township School District

2026 Decisions

USDC for the District of New Jersey

Mmu: 03/02/26-03/08/26, Student Bar Association

Monday Morning Update

This Week @ NDLS

Mass Times

Commons Daily Menu

Saint of the Week

General Announcements

Biochemical Phenotype Of Hypophosphatasia In Asymptomatic Individuals Carrying Alpl Variants., Rodrigo Montero-Lopez, Mariam R. Farman, Florian Högler, Catherine Rehder, Theodora Malli, Gerald Webersinke, Cheryl Rockman-Greenberg, Kathryn Dahir, Gabriel Ángel Martos-Moreno, Agnès Linglart, Keiichi Ozono, Lothar Seefried, Guillermo Del Angel, Erica Burner Nading, Erin Huggins, Eric T. Rush, Josephine T. Tauer, Priya S. Kishnani, Wolfgang Högler

Manuscripts, Articles, Book Chapters and Other Papers

Hypophosphatasia (HPP) is the rare metabolic disorder caused by variants in the ALPL gene, resulting in deficient activity of tissue-nonspecific alkaline phosphatase (ALP). This leads to accumulation of substrates contributing to impaired bone mineralization. Hypophosphatasia manifests with a broad clinical spectrum; however, an increasing number of individuals with ALPL variants have been identified presenting the hallmark biochemical feature of HPP of low serum ALP activity, with or without elevated serum pyridoxal-5-phosphate (PLP) or urine phosphoethanolamine (PEA), while remaining asymptomatic. These ALPL carriers may represent a distinct subgroup within the HPP continuum, prompting the need for clearer classification. Using data from …

Leveraging Csr To Buffer Brand Challenges During Crises: A Saudi Arabian Perspective, Nouf Alrayes, Abdullah Alhidari

Journal of Marketing and Consumer Behaviour in Emerging Markets

Crises, such as economic downturns or global health pandemics, pose significant business challenges. Engaging in CSR initiatives that contribute to societal well-being can help mitigate the negative consequences of crises, reinforce customer gratitude, and minimize corporate hypocrisy. CSR is critical in shaping a company’s accountability and ethical responsibilities. Consequently, there is an opportunity for the firm to see the role of CSR and how it affects customers’ responses and attitudes during any difficult situation. Drawing upon attribution theory and the customer gratitude reciprocity cycle, a conceptual framework was developed to test the impact of CSR on the variables: corporate hypocrisy, …

Rooted Wisdom Ecofeminist Tarot, Daniella Orias

Electronic Theses and Dissertations

This dissertation explores the potential of applying tarot as a pedagogical tool in connection with ecofeminist theories in order to assess if tarot can be a meaningful pedagogical modality to improve learner comprehension. The dissertation is guided by six research questions, explored in the introduction section, in order to examine how tarot embodies ecofeminist critiques of dualistic Western thought. In Chapter 1, the dissertation begins by providing a foundational understanding of ecofeminism, tarot, and pedagogy in order to provide key background information and assess the current conversations around ecofeminism, queer and nature-based tarot decks, and the basis of critical pedagogy. …