Digital Commons Network^™

Women Of Colour And Black Women Leaders Are Underrepresented In Architectural Firms Featured In Key Trade Publications, Nandi Prince

Publications and Research

No abstract provided.

Indian Tribal Governments: Problems And Challenges On The People's Road To Sovereignty, Americans For Indian Opportunity (Aio)

LaDonna Harris Native American Collection

This is a copy of an article manuscript providing basic information for a better understanding of the problems and challenges facing Native American tribes today in their efforts to gain more control over their destiny as sovereign peoples.

Ndls Communicator: Week Of 09.19.22, Notre Dame Law School

NDLS Communicator

The Latest News

• Class of 2022 builds on Notre Dame Law School’s strong tradition of securing clerkships
• ND Law’s Religious Liberty Clinic supports the Buddhist association in Alabama land use case
• Charity law scholars from around the world will gather in London
• The Religious Liberty Clinic files an amicus brief supporting en banc review in Apache Stronghold v. United States
• Members of the Notre Dame Black Law Students Association share what the group means to them on campus and beyond.
• The Wrongful Conviction podcast tells the story of Andy Royer, the first ND Law Exoneration Justice Clinic client to be …

Uav-Assisted Sensor Data Dissemination In Mmwave Vehicular Networks Based On Network Coding, Shidong Huang, Chuanhe Huang, Dongfang Wu, Yabo Yin, M. Wasim Abbas Ashraf, Bin Fu

Computer Science Faculty Publications

Due to good maneuverability, UAVs and vehicles are often used for environment perception in smart cities. In order to improve the efficiency of sensor data sharing in UAV-assisted mmWave vehicular network (VN), this paper proposes a sensor data sharing method based on blockage effect identification and network coding. The concurrent sending vehicles selection method is proposed based on the availability of mmWave link, the number of target vehicles of sensor data packet, the distance between a sensor data packet and target vehicle, the number of concurrent sending vehicles, and the waiting time of sensor data packet. The construction method of …

Generation And Validation Of An Anti-Human Pank3 Mouse Monoclonal Antibody, Sunada Khadka, Long Vien, Paul Leonard, Laura Bover, Florian Muller

Faculty, Staff and Student Publications

Coenzyme A (CoA) is an essential co-factor at the intersection of diverse metabolic pathways. Cellular CoA biosynthesis is regulated at the first committed step-phosphorylation of pantothenic acid-catalyzed by pantothenate kinases (PANK1,2,3 in humans, PANK3 being the most highly expressed). Despite the critical importance of CoA in metabolism, the differential roles of PANK isoforms remain poorly understood. Our investigations of PANK proteins as potential precision oncology collateral lethality targets (PANK1 is co-deleted as part of the PTEN locus in some highly aggressive cancers) were severely hindered by a dearth of commercial antibodies that can reliably detect endogenous PANK3 protein. While …

Mucopolysaccharidoses And The Blood-Brain Barrier, Akihiko Urayama

Faculty, Staff and Student Publications

Mucopolysaccharidoses comprise a set of genetic diseases marked by an enzymatic dysfunction in the degradation of glycosaminoglycans in lysosomes. There are eight clinically distinct types of mucopolysaccharidosis, some with various subtypes, based on which lysosomal enzyme is deficient and symptom severity. Patients with mucopolysaccharidosis can present with a variety of symptoms, including cognitive dysfunction, hepatosplenomegaly, skeletal abnormalities, and cardiopulmonary issues. Additionally, the onset and severity of symptoms can vary depending on the specific disorder, with symptoms typically arising during early childhood. While there is currently no cure for mucopolysaccharidosis, there are clinically approved therapies for the management of clinical symptoms, …

How Much Does The Board Composition Matter? The Impact Of Board Gender Diversity On Ceo Compensation, T Nawaz

Plymouth Business School

The notion that female directors are better disposed to protect shareholders’ interests has brought boardroom gender diversity into the limelight. Echoing these emerging trends, this paper analyzes the relationship between board gender diversity, i.e., proportion of female directors on the corporate board, and Chief Executive Officer’s (CEO) compensation. Consistent with conjecture, the analysis suggests that large and diversified corporate boards are the main determinants of CEO compensation. Furthermore, longer-tenured CEOs who also serve as board chairperson receive higher total compensation and bonuses than their counterparts do. Into the bargain are corporate performance proxied by return of assets (ROA) and firm …

Nethnography, Complementing Netnography: A Defensible Praxis For The Online Researcher, Martin Maccarthy

Research outputs 2022 to 2026

This article issues a challenge for interpretive tourism researchers to consider the trove of online data currently disavowed by aficionados of Netnography. Non-dyadic social media data is used by researchers but has been devalued as lacking legitimacy. However, by combining ‘lifeless’ non-dyadic social media with lesser-engaged ethnographic methods a lived proxy can be achieved. Nethnography is a two-part qualitative praxis of spending enough time with the phenomenon to discern meanings with confidence, which is then used to interpret non-dyadic textual discourse. Lesser-engaged ethnographic methods include participants as observers, observers as participants and complete observers. A fourth legitimizer of online interpretation …

Integrated Stem Cell Signature And Cytomolecular Risk Determination In Pediatric Acute Myeloid Leukemia., Benjamin J. Huang, Jenny L. Smith, Jason E. Farrar, Yi-Cheng Wang, Masayuki Umeda, Rhonda E. Ries, Amanda R. Leonti, Erin Crowgey, Scott N. Furlan, Katherine Tarlock, Marcos Armendariz, Yanling Liu, Timothy I. Shaw, Lisa Wei, Robert B. Gerbing, Todd M. Cooper, Alan S. Gamis, Richard Aplenc, E Anders Kolb, Jeffrey Rubnitz, Jing Ma, Jeffery M. Klco, Xiaotu Ma, Todd A. Alonzo, Timothy Triche, Soheil Meshinchi

Manuscripts, Articles, Book Chapters and Other Papers

Relapsed or refractory pediatric acute myeloid leukemia (AML) is associated with poor outcomes and relapse risk prediction approaches have not changed significantly in decades. To build a robust transcriptional risk prediction model for pediatric AML, we perform RNA-sequencing on 1503 primary diagnostic samples. While a 17 gene leukemia stem cell signature (LSC17) is predictive in our aggregated pediatric study population, LSC17 is no longer predictive within established cytogenetic and molecular (cytomolecular) risk groups. Therefore, we identify distinct LSC signatures on the basis of AML cytomolecular subtypes (LSC47) that were more predictive than LSC17. Based on these findings, we build a …

Laser Stimulation Of The Skin For Quantitative Study Of Decision-Making And Motivation, Julia Pai, Takaya Ogasawara, Ethan S Bromberg-Martin, Kei Ogasawara, Robert W Gereau, Ilya E Monosov

2020-Current year OA Pubs

Neuroeconomics studies how decision-making is guided by the value of rewards and punishments. But to date, little is known about how noxious experiences impact decisions. A challenge is the lack of an aversive stimulus that is dynamically adjustable in intensity and location, readily usable over many trials in a single experimental session, and compatible with multiple ways to measure neuronal activity. We show that skin laser stimulation used in human studies of aversion can be used for this purpose in several key animal models. We then use laser stimulation to study how neurons in the orbitofrontal cortex (OFC), an area …

Functional Determination Of Calcium-Binding Sites Required For The Activation Of Inositol 1,4,5-Trisphosphate Receptors, Vikas Arige, Lara E. Terry, Larry E. Wagner, Sundeep Malik, Mariah R. Baker, Guizhen Fan, Suresh K. Joseph, Irina I Serysheva, David I. Yule

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Inositol 1,4,5-trisphosphate receptors (IP3Rs) initiate a diverse array of physiological responses by carefully orchestrating intracellular calcium (Ca2+) signals in response to various external cues. Notably, IP3R channel activity is determined by several obligatory factors, including IP3, Ca2+, and ATP. The critical basic amino acid residues in the N-terminal IP3-binding core (IBC) region that facilitate IP3 binding are well characterized. In contrast, the residues conferring regulation by Ca2+ have yet to be ascertained. Using comparative structural analysis of Ca2+-binding sites identified in two main families of intracellular Ca2+-release channels, ryanodine receptors (RyRs) and IP3Rs, we identified putative acidic residues coordinating Ca2+ …

Systems And Methods For Machine Learning Brand Identification Models, Roy Palacios, Pallavi Satyan

Defensive Publications Series

A high precision machine learning model trained to identify brands is described. One or more machine-learned models are trained to create signals for top product categories at the brand/merchant level and brand signals from a custom Brand Ownership Service based on external digital brand signals such as trademark data from the USPTO, the EUIPO, and/or other trademark registries.

Thunderbolt Add-In Card With Detachable Pd Supported, Hp Inc

Defensive Publications Series

Most Thunderbolt (TBT) add-in card solutions, there are several PDP (PD power) ratings defined in the spec across 15W, 27W, 45W, 60W, 100W, 140W, 180W and 240W…etc. It makes customer feels dilemma to make the decision to expand their system. The innovation idea here provides the perfect solution to fulfill customer requirements.

Water Fog Cooling In Pc, Hp Inc

Defensive Publications Series

This invention is to enhance PC performance by adding water fog in the system fan outlet. Enhance PC performance by lower heatsink temperature. Lowering heatsink temperature can be done by higher airflow speed and lower airflow temperature. Limited spacing and heatsink design and constrain CPU performance. CPU temperature will impact the boost behavior and duration. FAN speed and acoustic noise concern.

Poka-Yoke Mechanism For Drums Of Powder For 3d Printing, Hp Inc

Defensive Publications Series

In the 3D printing facilities with selective powder fusing technology printers, different types of fresh and recovered powder materials are managed. They are visually similar and usually stored in the same type of drums, so it may happen that an operator takes the wrong drum. If a machine is fed with wrong material, the result will be part quality problems, damages in the printer and scrap of expensive material. To avoid these mistakes, the drums can be identified with labels, barcodes or color codes. These are not robust solutions because they are operator dependent. Another solution is RFID identification technology, …

Adjustment Mechanism To Calibrate The Roller Height By Means Of A Differential Screw, Hp Inc

Defensive Publications Series

On an additive manufacturing 3D printer, parts are constructed by forming thin layers of pulverized material and selectively melting or binding it. To have a good part quality it is important to control the distance between the print heads and the powder bed surface. It can be achieved by calibrating the height of the roller with respect the print head carriage with a proper mechanism. In this article, a mechanism is described to precisely calibrate the height of the roller by means of a differential screw combined with a lever to ensure adjustment is fine enough.

A Solution To Enhance Office Conference Experience By Non-Contact Floating-In-Air User Interface, Hp Inc

Defensive Publications Series

In the post covid‐19 pandemic era, more and more persons come back to office. Comparing with the ear before covid‐19 pandemic, one important thing changed eco system is user pay more care about to keep themselves away from the virus. Since this design mainly tends to set the product in a public place, considering that if the user directly touches it, it will greatly increase the possibility of pathogenic disease, so the input is selected in a non‐touch manner. User do care the interface they touched in public area and want to make sure if the device can provide a …

Water-Powered Dryer For Latex Printers, Hp Inc

Defensive Publications Series

Sustainability is one of the hot topics of this decade. Latex inks are a great example of sustainable printing technology, but the energy used by the dryer can be optimized to reduce the consumption. Today most of the dryers use hot‐air, and the energy comes from resistors. The idea is to use a hybrid system to dry the Latex ink thermal energy that comes from hot water solar panels, with additional resistor‐based dryers used only as additional power source in case of cloudy or nightly working hours. The system can be centralized in a printing plant to serve a fleet …

Deserializing And Exposing In-Memory Columnar Olap/Oltp Data, Prashant Mishra

Defensive Publications Series

This disclosure describes high-performance techniques of using a client library to access data from OLAP or OLTP databases. Data is transported between the database and the client library in a columnar in-memory format such as Apache Arrow over a binary protocol such as RPC. RPC is significantly faster than REST when receiving data due to the use of protocol Buffers and HTTP/2. In addition, Apache Arrow is zero-copy and does efficient in-memory computations. The stream of data is processed in separate parser threads, thus maximizing concurrency and parallel processing. This makes the client library an order of magnitude faster than …

Estimating Interpupillary Distance From Eyeball Size, Rees Simmons, Idris Aleem

Defensive Publications Series

The interpupillary distance (IPD) of a user’s face is used to frame prescription or non-prescription glasses, or other eyewear. The requirement for an IPD measurement necessitates a physical visit to an optometrist, making online glass (or frame) orders or virtual try-ons (VTO), difficult or infeasible. This disclosure leverages the near constancy of eyeball diameter across the human population to predict the IPD using geometric and/or machine learning techniques. The visible portion of the eyeball (the iris) is used to infer eyeball position. The eyeball position and a priori known size serve as reference dimensions to determine the IPD and/or dimensions …

Birth Control And The Sixties: The Dialogue Surrounding The First Oral Contraceptive, Eden E. Baize

The Cardinal Edge

No abstract provided.

Multi-Decadal Analysis Of Remotely Sensed Vegetation Change In Berea College Forest - Seasonality Of Forest Patterns Using Remote Sensing, Jacob Foushee

The Cardinal Edge

Satellite imagery is a practical and valuable tool for monitoring vegetation condition in forests. The longevity of the USGS/NASA Landsat program along with its medium spatial resolution (30m) gives researchers the ability to make informed statements on land cover generally, and specifically on aspects such as forest conditions. The Landsat program’s nearly 50-year archive of imagery show how Earth’s surface has changed through modern development and how these developments have influenced forests. Google Earth Engine (GEE) is a cloud-based repository of satellite imagery dating as far back as the 1970s. This study utilizes Landsat 5-8 imagery from GEE to calculate …

The Great Resignation Among Restaurant Workers: A Content Analysis Of News Sources’ Portrayals Of The Covid-19 Labor Shortage, Mackenzie M. Williams

The Cardinal Edge

When workers left the labor market in large numbers during the COVID-19 pandemic, proclamations of a labor shortage emerged extensively throughout the news. In this study, I analyze the coverage of the worker shortage among three news sources with different political orientations. Several themes emerged from analyzing a total of 75 articles. The findings showed that the perspective shown in the article, the cause of the labor shortage, restaurant worker portrayal, support of solutions, and opinion of the labor shortage all differed based on the political identity of the news source. This research supports previous findings that show there is …

"Moral Panic" In The Sixties: The Rise And Rapid Declination Of Lsd In American Society, Abigail M Stanger

The Cardinal Edge

No abstract provided.

An Evaluation Of Covid-19 Vaccination Rates Of The Patients At The Kentucky Racing Health Services Center, Aditya Mehta, Dedra Hayden

The Cardinal Edge

COVID-19 vaccines have been widely available to the U.S. public since early 2021. However, vaccination rates still vary considerably across geographical areas and different populations. The objective of this study was to research overall vaccination rates against COVID-19 for Latinx patients at the Kentucky Racing Health Services Center (KRHSC). Vaccination and booster data was collected from June to December 2021 for all unique patients visiting the center. It was initially hypothesized that these rates of vaccination and booster doses for the KRHSC patients would be lower than the data reported by Kentucky and Jefferson County. After a retrospective review, the …

The Economic Behavior Of Restaurant Tipping: The Effect Of Tipping On Profit, Golnoush Esmaeily

The Cardinal Edge

This paper explores the potential motivations behind restaurant tipping and its effect on profit. The analysis discovers several reasons that motivate people to tip in a restaurant, including exemplary service quality, future service, and social norms. Initially, tipping was used to encourage service quality, but it shifted to become the desire to conform to the social norm. Customers aim to prevent embarrassment and unfairness that may result from not tipping or lacking empathy for the worker. A survey was conducted with 40 Louisville customers and 16 Louisville servers soliciting their opinion about their tipping behavior. The quantitative study results show …

Chisholm V. Georgia (1793): Laying The Foundation For Supreme Court Precedent, Abigail Stanger

The Cardinal Edge

No abstract provided.

The Yellow Figment Of East Asian American Women: A Case Study Of The 2021 Atlanta Spa Shootings, Lily Z. Stewart

The Cardinal Edge

This paper explores how mainstream media frames the racial gendering of Asian women through a case study of the 2021 Atlanta Spa Shootings. Fifteen articles sourced from the top ten national newspaper entities published between March 16^th, 2021 and October 2021 analyze how Asian American women are subjected to at least a double feminized social location on account of their race and gender within a U.S. contemporary context. I explore how themes of race, gender, and hyper-sexualization intersect to produce the archetype of Asian women as exotic, docile temptresses. This analysis centers around the dynamic between Asian women …

A Roller Coaster For The Mind: Virtual Reality Sickness Modes, Metrics, And Mitigation, Dalton C. Sparks

The Cardinal Edge

Understanding and preventing virtual reality sickness(VRS), or cybersickness, is vital in removing barriers for the technology's adoption. Thus, this article aims to synthesize a variety of academic sources to demonstrate the modes by which VRS occurs, the metrics by which it is judged, and the methods to mitigate it. The predominant theories on the biological origins of VRS are discussed, as well as the individual factors which increase the likelihood of a user developing VRS. Moreover, subjective and physiological measurements of VRS are discussed in addition to the development of a predictive model and conceptual framework. Finally, several methodologies of …

A Study Of Multiple Sclerosis, Christine Chen

The Cardinal Edge

No abstract provided.