Digital Commons Network^™

Fundamental Neutron Physics At Spallation Sources, Nadia Fomin, Jason Fry, Robert W. Pattie Jr., Geoffrey L. Greene

EKU Faculty and Staff Scholarship

Low-energy neutrons have been a useful probe in fundamental physics studies for more than 70 years. With advances in accelerator technology, many new sources are spallation based. These new, high-flux facilities are becoming the sites for many next-generation fundamental neutron physics experiments. In this review, we present an overview of the sources and the current and upcoming fundamental neutron physics programs.

Bristol And Newport And The Transatlantic Slave Trade 09-01-2022, Roger Williams University School Of Law

School of Law Conferences, Lectures & Events

No abstract provided.

A Study Of Pressure Probe Response In Steady And Unsteady Flows, Michael T. Charonnat

Master's Theses

The objective of this thesis is two-fold: to analyze the directional calibration of a 3-hole probe in steady flow and to develop a method for the interpretation of measurements recorded with a novel, fast-response Pitot-type probe in unsteady, turbulent flow. Calibration data for the 3-hole probe’s two side ports was taken in the steady, non-turbulent region of a free jet and was evaluated for symmetry. In addition, data that was recorded using one side port in two independent calibration runs was compared to study repeatability. Misalignment was found between the nominally symmetric data sets, which may be the result of …

Commercial Space Companies: Lawmakers Of 21st Century New Space, Hongxi Wang

Journal of Space Law

No abstract provided.

Lunar Missions By Newer Space Actors In The Next Five Years: An Evaluation Of Legal Issues, Upasana Dasgupta

Journal of Space Law

No abstract provided.

Front Matter, Journal Editors

Journal of Space Law

Includes table of contents.

From The Editor, Michelle L. D. Hanlon

Journal of Space Law

No abstract provided.

Providing Clarity For Fault-Based Liability In International Space Law: A Practical Approach Through Principles Of General International Law, Tyler J. Sena

Journal of Space Law

No abstract provided.

The Artemis Plan: A Paradigm Shift In International Law?, Rossana Deplano

Journal of Space Law

No abstract provided.

The Perils Of Plurality: Revisiting The Making Of The International Law Of The Moon, S. G. Sreejith

Journal of Space Law

No abstract provided.

Tracking The Evolution Of Customary Rules In International Space Law, Berfin Bediz Yildiz Keskin

Journal of Space Law

No abstract provided.

The Odyssey Of European Space Policy, Maria Castillo

Journal of Space Law

No abstract provided.

Water Insecurity And Gender-Based Violence: A Global Review Of The Evidence, Paula S. Tallman, Shalean Collins, Gabriela Salmon-Mulanovich, Binahayati Rusyidi, Aman Kothadia, Stroma Cole

Anthropology: Faculty Publications and Other Works

We reviewed the existing literature documenting the association between water insecurity and gender-based violence to (1) describe the characteristics and contexts of available studies, and (2) identify and classify documented gender-based violence across domains of water insecurity (access, affordability, adequacy, reliability, and safety). 18 peer-reviewed articles mentioned associations between water insecurity and gender-based violence. All studies were conducted in sub-Saharan Africa and South Asia and were published in English. The most common manifestation of the relationship between water insecurity and gender-based violence was an increased risk of sexual and physical violence for women who walked long distances to access water. …

The Asymmetric Effects Of External Debt On Economic Growth In Selected Mena Countries: Some Insights From A Panel Quantile Regression, Mahmoud Haddad, Refk Selmi, Shawkat Hammoudeh

Topics in Middle Eastern and North African Economies

The increased level of debt is a major risk for the financial stability and questions the ability of countries to balance fiscal vulnerabilities with development goals. With the rising debt wave and additional pressures induced by the pandemic and the Russian/Ukrainian war on sources of development finance, this study uses a panel quantile regression to re-examine the asymmetric relationship between the external debt and economic growth in six highly indebted MENA countries, namely, Bahrain, Egypt, Jordan, Lebanon, Morocco and Tunisia over the period 2006-2019. The outcomes support the main hypothesis that high debt reduces economic growth, yet this effect seems …

Medical–Surgical Nurse Leaders' Experiences With Safety Culture: An Inductive Qualitative Descriptive Study, Lisa Harton, Lisa E. Skemp

Nursing: School of Nursing Faculty Publications and Other Works

The aim of this study is to describe safety culture as experienced by medical–surgical nurse leaders.BackgroundSafety culture remains a barrier in safer patient care. Nurse leaders play an important role in creating and supporting a safety culture.MethodsWe used an inductive qualitative descriptive study using semistructured interviews, document review and observations in a Midwestern community hospital in the United States.ResultsResults of the study are as follows: making sure nurses are keeping patients safe, making sure nurses have nursing interventions in place, expecting nurses to stop unsafe acts or escalate when they feel uncomfortable, making sure nurses have what they need to …

Low Energy Event Reconstruction In Icecube Deepcore, R. Abbasi, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, J. M. Alameddine, A. A. Alves, N. M. Amin, K. Andeen, T. Anderson, G. Anton, C. Argüelles, Y. Ashida, S. Axani, X. Bai, V. A. Balagopal, S. W. Barwick, B. Bastian, V. Basu, S. Baur, R. Bay, J. J. Beatty, K. H. Becker, J. Becker Tjus

Physics: Faculty Publications and Other Works

The reconstruction of event-level information, such as the direction or energy of a neutrino interacting in IceCube DeepCore, is a crucial ingredient to many physics analyses. Algorithms to extract this high level information from the detector’s raw data have been successfully developed and used for high energy events. In this work, we address unique challenges associated with the reconstruction of lower energy events in the range of a few to hundreds of GeV and present two separate, state-of-the-art algorithms. One algorithm focuses on the fast directional reconstruction of events based on unscattered light. The second algorithm is a likelihood-based multipurpose …

Dino Shindig 2022, Carter County Museum, Megan Tanner Schultz

Institute for Tourism and Recreation Research Publications

This study was conducted for the Carter County Museum to provide insight into the characteristics of attendees of the 2022 Dino Shindig. Surveys on site implemented via a tablet and iForm survey software were collected and a post-event web survey were completed by a total of 84 attendees and/or participants of the event. Results show that 54% of respondents were residents of Montana and of those Montana residents, 18% were from Carter County. Results provide event organizers and the Carter County Museum with useful data for future event planning, making improvements to the event, event marketing/promotion, and understanding the visitor …

Montana Travel Experience Survey: Summary Report, Kara Grau

Institute for Tourism and Recreation Research Publications

This summary report highlights select findings from the nonresident 2021-2022 Montana Travel Experience Survey. Data included here were collected from late May, 2021 through June, 2022. 1,327 surveys were collected. Questions included topics related to visitors’ use of public lands, trip planning, and questions for first time and repeat visitors.

Montana Trends: Montanans' Consumer Confidence & Expectations For Income, Travel, And Recreation, Carter Bermingham, Matthew Pettigrew, Megan Schultz, Josh Martin

Institute for Tourism and Recreation Research Publications

This report is a summary of Montana residents and their expectations related to spending, personal income, travel, and recreation over the next 12 months. ITRR conducted a similar study in 2019, aimed at understanding the current trends of consumer confidence in addition to residents' expectations for travel plans over a one year time horizon. Since that time, much has changed, including the COVID-19 pandemic and increased demand for the MT tourism industry, rising gas prices, and inflation at historic levels. This report highlights residents' sentiments regarding fuel prices, personal income, and travel.

The Normal Review, A Literary And Arts Publication, Fall 2022, The Normal Review

The Normal Review

No abstract provided.

The Effect Of Scent Lures On Detection Is Not Equitable Among Sympatric Species Data, Marlin M. Dart, Lora B. Perkins, Jonathan A. Jenks, Gary Hatfield, Robert C. Lonsinger

NRM Departmental Data Sets

This data represents wildlife detection data resulting from a camera trapping survey conducted in southcentral South Dakota during summer 2019, along with information on sites surveyed, treatments applied, and environmental conditions during sampling.

Each files contains data associated with different sampling stations; wildlife species detection data, site specific data, and survey specific environmental conditions. The files all contain a common field (i.e., ‘Station’) to indicate this relationship.

Downloadable zip file contains the following data:

1. Dart et al_Species_Detection_Data.txt
2. Dart et al_Site_Data.txt
3. Dart et al_Survey_Data.txt

The Impact Of Information-Seeking Self-Efficacy And Online Learning Self-Efficacy On Students’ Performance Proficiency, Yingqi Tang, Hungwei Tseng, Xingyi Tang

Research, Publications & Creative Work

This study surveyed 359 online undergraduate and graduate students regarding their information-seeking self-efficacy, online learning self-efficacy, and performance proficiency. A mediation model was conducted to examine the direct effect of students' online learning self-efficacy on their performance proficiency and the mediation effect of information-seeking self-efficacy. Multivariate correlational analysis showed that all three variables significantly correlated. Of the three variables, online learning self-efficacy has the strongest correlation to performance proficiency, while the variable with the least amount of correlation is between online-learning and information-seeking efficacies. Moreover, a significant regression equation showed that students' average performance proficiency increased by 0.359 for each …

The Insulin Receptor Regulates The Persistence Of Mechanical Nociceptive Sensitization In Flies And Mice, Tatiana V Karpinets, Xiaogang Wu, Travis Solley, Molly B El Alam, Travis T Sims, Kyoko Yoshida-Court, Erica Lynn, Mustapha Ahmed-Kaddar, Greyson Biegert, Jingyan Yue, Xingzhi Song, Huandong Sun, Joseph F Petrosino, Melissa P Mezzari, Pablo Okhuysen, Patricia J Eifel, Anuja Jhingran, Lilie L Lin, Kathleen M Schmeler, Lois Ramondetta, Nadim Ajami, Robert R Jenq, Andrew Futreal, Jianhua Zhang, Ann H Klopp, Lauren E Colbert

Faculty, Staff and Student Publications

Early phase diabetes is often accompanied by pain sensitization. In Drosophila, the insulin receptor (InR) regulates the persistence of injury-induced thermal nociceptive sensitization. Whether Drosophila InR also regulates the persistence of mechanical nociceptive sensitization remains unclear. Mice with a sensory neuron deletion of the insulin receptor (Insr) show normal nociceptive baselines; however, it is uncertain whether deletion of Insr in nociceptive sensory neurons leads to persistent nociceptive hypersensitivity. In this study, we used fly and mouse nociceptive sensitization models to address these questions. In flies, InR mutants and larvae with sensory neuron-specific expression of RNAi …

Efficacy And Safety Of Topical Hypericin Photodynamic Therapy For Early-Stage Cutaneous T-Cell Lymphoma (Mycosis Fungoides): The Flash Phase 3 Randomized Clinical Trial, Ellen J Kim, Aaron R Mangold, Jennifer A Desimone, Henry K Wong, Lucia Seminario-Vidal, Joan Guitart, James Appel, Larisa Geskin, Edward Lain, Neil J Korman, Nathalie Zeitouni, Neda Nikbakht, Kenneth Dawes, Oleg Akilov, Joi Carter, Michi Shinohara, Timothy M Kuzel, Warren Piette, Neal Bhatia, Amy Musiek, David Pariser, Youn H Kim, Dirk Elston, Erin Boh, Madeleine Duvic, Auris Huen, Theresa Pacheco, Jeffrey P Zwerner, Seung Tae Lee, Michael Girardi, Christiane Querfeld, Kimberly Bohjanen, Elise Olsen, Gary S Wood, Adam Rumage, Oreola Donini, Andrea Haulenbeek, Christopher J Schaber, Richard Straube, Christopher Pullion, Alain H Rook, Brian Poligone

Faculty, Staff and Student Publications

IMPORTANCE: Given that mycosis fungoides-cutaneous T-cell lymphoma (MF/CTCL) is chronic, there is a need for additional therapies with minimal short- and long-term adverse effects. Topical synthetic hypericin ointment, 0.25%, activated with visible light is a novel, nonmutagenic photodynamic therapy (PDT).

OBJECTIVES: To determine the efficacy and safety of topical synthetic hypericin ointment, 0.25%, activated with visible light as a nonmutagenic PDT in early-stage MF/CTCL.

DESIGN, SETTINGS, AND PARTICIPANTS: This was a multicenter, placebo-controlled, double-blinded, phase 3 randomized clinical trial (FLASH study) conducted from December 2015 to November 2020 at 39 academic and community-based US medical centers. Participants were adults (≥18 …

Arkansas Wheat Performance Tests 2021-2022, J. F. Carlin, R. B. Morgan, R. D. Bond, D. E. Moon

Arkansas Agricultural Experiment Station Research Series

Wheat variety performance tests are conducted each year in Arkansas by the University of Arkansas System Division of Agriculture’s Arkansas Agricultural Experiment Station, Department of Crop, Soil, and Environmental Sciences. The tests provide information to companies developing varieties and marketing seed within the state and aid the Arkansas Cooperative Extension Service in formulating variety recommendations for small-grain producers. The tests are conducted at the Northeast Research and Extension Center at Keiser, the Vegetable Substation near Kibler, the Lon Mann Cotton Research Station near Marianna, the Pine Tree Research Station near Colt, and the Rohwer Research Station near Rohwer. Specific location …

Mass Transport Model Of Radiation Response: Calibration And Application To Chemoradiation For Pancreatic Cancer, Charles X Wang, Dalia Elganainy, Mohamed M Zaid, Joseph D Butner, Anshuman Agrawal, Sara Nizzero, Bruce D Minsky, Emma B Holliday, Cullen M Taniguchi, Grace L Smith, Albert C Koong, Joseph M Herman, Prajnan Das, Anirban Maitra, Huamin Wang, Robert A Wolff, Matthew H G Katz, Christopher H Crane, Vittorio Cristini, Eugene J Koay

Faculty, Staff and Student Publications

PURPOSE: The benefit of radiation therapy for pancreatic ductal adenocarcinoma (PDAC) remains unclear. We hypothesized that a new mechanistic mathematical model of chemotherapy and radiation response could predict clinical outcomes a priori, using a previously described baseline measurement of perfusion from computed tomography scans, normalized area under the enhancement curve (nAUC).

METHODS AND MATERIALS: We simplified an existing mass transport model that predicted cancer cell death by replacing previously unknown variables with averaged direct measurements from randomly selected pathologic sections of untreated PDAC. This allowed using nAUC as the sole model input to approximate tumor perfusion. We then compared the …

Impact Of Medicaid Expansion Under The Affordable Care Act On Receipt Of Surgery For Breast Cancer, Leisha C Elmore, Meng Li, Heather Lin, Yu Shen, Simona F Shaitelman, Gildy Babiera, Nina Tamirisa, Isabelle Bedrosian

Faculty, Staff and Student Publications

To determine whether Medicaid expansion under the 2010 Affordable Care Act affected rates of breast cancer surgery.

Background: Data regarding the impact of Medicaid expansion on access to surgical treatment of breast cancer are limited.

Methods: Patients in the National Cancer Database diagnosed with non-metastatic breast cancer between January 1, 2010 and December 31, 2017 and residing in a state that expanded Medicaid in January 2014 or in a state that opted out of expansion were included. A quasi-experimental, difference-in-differences (DID) approach was used to assess rate of omission of surgical treatment.

Results: Of 624,237 patients diagnosed with invasive breast …

Addressing Patient Heterogeneity In Disease Predictive Model Development, Xu Gao, Weining Shen, Jing Ning, Ziding Feng, Jianhua Hu

Faculty, Staff and Student Publications

This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of subgroups in patient population if subgroups exist. A mixture of generalized linear models is considered to model the relationship between the disease outcome and patient characteristics and clinical factors, including targeted biomarker profiles. We construct a test statistic based on expectation maximization (EM) algorithm and derive its asymptotic distribution under the null hypothesis. An important computational advantage of the test is that the involved parameter estimates under the complex …

Bintrafusp Alfa, An Anti-Pd-L1:Tgf-Β Trap Fusion Protein, In Patients With Ctdna-Positive, Liver-Limited Metastatic Colorectal Cancer, Van K Morris, Michael J Overman, Michael Lam, Christine M Parseghian, Benny Johnson, Arvind Dasari, Kanwal Raghav, Bryan K Kee, Ryan Huey, Robert A Wolff, John Paul Shen, June Li, Isabel Zorrilla, Ching-Wei D Tzeng, Hop S Tran Cao, Yun Shin Chun, Timothy E Newhook, Nicolas Vauthey, Dzifa Duose, Raja Luthra, Cara Haymaker, Scott Kopetz

Faculty, Staff and Student Publications

Background: Identification of circulating tumor DNA (ctDNA) following curative intent therapies is a surrogate for microscopic residual disease for patients with metastatic colorectal cancer (mCRC). Preclinically, in micrometastatic microsatellite stable (MSS) CRC, increased TGF-β signaling results in exclusion of anti-tumor cytotoxic T cells from the tumor microenvironment. Bintrafusp alfa (BA) is a bifunctional fusion protein composed of the extracellular domain of the TGF-βRII receptor ("TGF-β trap") and anti-PD-L1 antibody.

Methods: Patients with liver-limited, MSS mCRC and with detected ctDNA after complete resection of all known tumors and standard-of-care therapy were treated with 1200 mg of BA intravenously every 14 days …

Swallowing After Primary Tors And Unilateral Or Bilateral Radiation For Low- To Intermediate-Risk Tonsil Cancer, Carly E A Barbon, Christopher M K Yao, Christine B Peterson, Amy C Moreno, Ryan P Goepfert, Faye M Johnson, Gregory M Chronowski, Clifton D Fuller, Neil D Gross, Katherine A Hutcheson

Faculty, Staff and Student Publications

Objective: The primary course of treatment for patients with low- to intermediate-risk tonsil cancer has evolved with a shift toward primary transoral robotic surgery (TORS) or radiation therapy (RT). While favorable outcomes have been reported after deintensification via unilateral TORS or RT (uniRT), comparisons of functional outcomes between these treatments are lacking. We compared clinical outcomes (Dynamic Imaging Grade of Swallowing Toxicity [DIGEST] and feeding tube [FT]) and patient-reported swallowing outcomes (MD Anderson Dysphagia Inventory [MDADI]) based on primary treatment strategy: TORS, uniRT, or bilateral RT (biRT).

Study design: Secondary analysis of prospective cohort.

Setting: Single institution.

Methods: The study …