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Differing Moisture Content In Concrete And Mitigation Methods: Research Of Sacramento, Taylor S. Tonda Sep 2022

Differing Moisture Content In Concrete And Mitigation Methods: Research Of Sacramento, Taylor S. Tonda

Construction Management

The city of Sacramento and its concrete foundations face one of the most challenging conditions in the flooring industry, high RH Moisture. RH Moisture or Relative Humidity Moisture is one of the main causes for flooring systems to fail. The source of High RH Moisture consists of surrounding geographic features like rivers, flood plains, and elevation, as well as improper or nonexistent use of a vapor barrier beneath the concrete foundation. Mapping and other data is used to support these claims. If a flooring system is not properly prepared for high RH Moisture levels, issues such as bubbling, delamination, and …


Ultrafast Stiffening Of Concentrated Thermoresponsive Mineral Suspensions, Sharu Bhagavathi Kandy, Iman Mehdipour, Narayanan Neithalath, Aditya Kumar, Mathieu Bauchy, Edward Garboczi, Samanvaya Srivastava, Torben Gaedt, Gaurav Sant Sep 2022

Ultrafast Stiffening Of Concentrated Thermoresponsive Mineral Suspensions, Sharu Bhagavathi Kandy, Iman Mehdipour, Narayanan Neithalath, Aditya Kumar, Mathieu Bauchy, Edward Garboczi, Samanvaya Srivastava, Torben Gaedt, Gaurav Sant

Materials Science and Engineering Faculty Research & Creative Works

Extrusion-based 3D printing with rapidly hardening polymeric materials is capable of building almost any conceivable structure. However, concrete, one of the most widely used materials for large-scale structural components, is generally based on inorganic binder materials like Portland cement. Unlike polymeric materials, a lack of precise control of the extent and rate of solidification of cement-based suspensions is a major issue that affects the ability to 3D-print geometrically complex structures. Here, we demonstrate a novel method for controllable-rapid solidification of concentrated mineral suspensions that contain a polymer binder system based on epoxy and thiol precursors as well as one or …


Mechanical Activation And Cation Site Disorder In Mgal2o4, Cole A. Corlett, Matthias D. Frontzek, Nina Obradovic, Jeremy Lee Watts, William Fahrenholtz Sep 2022

Mechanical Activation And Cation Site Disorder In Mgal2o4, Cole A. Corlett, Matthias D. Frontzek, Nina Obradovic, Jeremy Lee Watts, William Fahrenholtz

Materials Science and Engineering Faculty Research & Creative Works

The synthesis and crystallographic site occupancy were investigated for MgAl2O4 with and without mechanical activation of the precursor powders. Heating to 1200 °C or higher resulted in the formation of a single spinel phase regardless of whether the powders were mechanically activated or not. Neutron diffraction analysis was used to determine cation site occupancy and revealed that mechanical activation resulted in a lower degree of cation site inversion compared to the nonactivated materials, which indicated that the powders were closer to thermodynamic equilibrium. This is the first study to characterize the effects of mechanical activation on crystallographic site occupancy in …


Best Practices For Reducing Construction Accidents Involving Hispanic Construction Workers, Michael E. Asuquo, Khalid Siddiqi Sep 2022

Best Practices For Reducing Construction Accidents Involving Hispanic Construction Workers, Michael E. Asuquo, Khalid Siddiqi

The Professional Constructor

The objective of this study was to determine best practices for reducing accidents among Hispanic construction workers. It was hypothesized that language barrier between the Hispanics and American workers contributed immensely to high rate of construction accidents on industrial projects. Accident case studies and questionnaire survey were both used. Data was collected through semi-structured interviews with Hispanic workers involved in industrial construction projects in Metro Atlanta. Findings from the study concluded that most accidents involving Hispanic workers were caused due to lack of communication from supervisors, ignorance of workers on work procedures, lack of equipment training, and worker negligence. Language …


Construction Management Internship: A Key Opportunity For Assessment And Continuous Curriculum Improvement, James S. Vaux, Bree Dority, Dana E. Vaux Sep 2022

Construction Management Internship: A Key Opportunity For Assessment And Continuous Curriculum Improvement, James S. Vaux, Bree Dority, Dana E. Vaux

The Professional Constructor

The internship is an integral part of most Construction Management curricula. Studies have noted the importance and reciprocal value of internships for the student, the employer, and the academic program. However, to date, no studies have specifically outlined the value internships provide to the CM program for assessment and evaluation. This paper examines the value of the CM internship as an indirect measure to assess and incorporate change into program curricula. With 10 years of qualitative and quantitative data collected from CM student interns, industry employers, and university internship supervisors, this study supports that CM internships are a valuable tool …


Social Media Mining Under The Covid-19 Context: Progress, Challenges, And Opportunities, Xiao Huang, Siqin Wang, Mengxi Zhang, Tao Hu, Alexander Hohl, Bing She, Jianxin Li, Xiao Liu, Oliver Gruebner, Regina Liu, Xiao Li, Zhewei Liu, Xinyue Ye, Zhenlong Li Sep 2022

Social Media Mining Under The Covid-19 Context: Progress, Challenges, And Opportunities, Xiao Huang, Siqin Wang, Mengxi Zhang, Tao Hu, Alexander Hohl, Bing She, Jianxin Li, Xiao Liu, Oliver Gruebner, Regina Liu, Xiao Li, Zhewei Liu, Xinyue Ye, Zhenlong Li

Geosciences Faculty Publications and Presentations

Social media platforms allow users worldwide to create and share information, forging vast sensing networks that allow information on certain topics to be collected, stored, mined, and analyzed in a rapid manner. During the COVID-19 pandemic, extensive social media mining efforts have been undertaken to tackle COVID-19 challenges from various perspectives. This review summarizes the progress of social media data mining studies in the COVID-19 contexts and categorizes them into six major domains, including early warning and detection, human mobility monitoring, communication and information conveying, public attitudes and emotions, infodemic and misinformation, and hatred and violence. We further document essential …


Evaluation Of Potassium Borate As A Volatility-Reducing Agent For Dicamba, Mason Castner, Jason K. Norsworthy, Trenton Roberts Sep 2022

Evaluation Of Potassium Borate As A Volatility-Reducing Agent For Dicamba, Mason Castner, Jason K. Norsworthy, Trenton Roberts

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Dicamba was labeled in dicamba-resistant cotton (Gossypium hirsutum L.) and soybean [Glycine max (L.) Merr.] in 2017, resulting in a record number of off-target complaints. To address off-target movement via volatilization, experiments were conducted to evaluate the effectiveness of potassium tetraborate tetrahydrate (KBo) as a volatility-reducing agent (VRA) with dicamba. Low-tunnel experiments examined: (1) whether KBo functions as a dicamba VRA, (2) the relationship between KBo concentration and dicamba volatilization, (3) the effectiveness of KBo compared with potassium acetate as a VRA, and (4) the impact of KBo on dicamba volatilization with and without glufosinate. In a large-scale trial (0.4-ha …


Construction Of Modular Concrete Footings For Use In Cal Poly’S High Bay Laboratory, Tyler W. Giddens Sep 2022

Construction Of Modular Concrete Footings For Use In Cal Poly’S High Bay Laboratory, Tyler W. Giddens

Construction Management

This project-based senior project had the end goal of creating two concrete modular foundations that can be used in the High Bay Laboratory for testing procedures. The concrete modular blocks are 6’ long by 3’ wide, and 1.5’ tall. The foundations each held 100 embeds. Each embed serves as an anchor point for various attachments for testing purposes. This was an interdisciplinary project amongst two CM students and one ARCE student. The ARCE student was responsible for the design of the blocks, encompassing the formwork and the rebar. The CM students were responsible for estimating, scheduling, and the construction of …


Genetic Loci And Prioritization Of Genes For Kidney Function Decline Derived From A Meta-Analysis Of 62 Longitudinal Genome-Wide Association Studies, Mathias Gorski, Humaira Rasheed, Alexander Teumer, Laurent F Thomas, Sarah E Graham, Gardar Sveinbjornsson, Thomas W Winkler, Felix Günther, Klaus J Stark, Jin-Fang Chai, Bamidele O Tayo, Matthias Wuttke, Yong Li, Adrienne Tin, Tarunveer S Ahluwalia, Johan Ärnlöv, Bjørn Olav Åsvold, Stephan J L Bakker, Bernhard Banas, Nisha Bansal, Mary L Biggs, Ginevra Biino, Michael Böhnke, Eric Boerwinkle, Erwin P Bottinger, Hermann Brenner, Ben Brumpton, Robert J Carroll, Layal Chaker, John Chalmers, Miao-Li Chee, Miao-Ling Chee, Ching-Yu Cheng, Audrey Y Chu, Marina Ciullo, Massimiliano Cocca, James P Cook, Josef Coresh, Daniele Cusi, Martin H De Borst, Frauke Degenhardt, Kai-Uwe Eckardt, Karlhans Endlich, Michele K Evans, Mary F Feitosa, Andre Franke, Sandra Freitag-Wolf, Christian Fuchsberger, Piyush Gampawar, Ron T Gansevoort, Mohsen Ghanbari, Sahar Ghasemi, Vilmantas Giedraitis, Christian Gieger, Daniel F Gudbjartsson, Stein Hallan, Pavel Hamet, Asahi Hishida, Kevin Ho, Edith Hofer, Bernd Holleczek, Hilma Holm, Anselm Hoppmann, Katrin Horn, Nina Hutri-Kähönen, Kristian Hveem, Shih-Jen Hwang, M Arfan Ikram, Navya Shilpa Josyula, Bettina Jung, Mika Kähönen, Irma Karabegović, Chiea-Chuen Khor, Wolfgang Koenig, Holly Kramer, Bernhard K Krämer, Brigitte Kühnel, Johanna Kuusisto, Markku Laakso, Leslie A Lange, Terho Lehtimäki, Man Li, Wolfgang Lieb, Lifelines Cohort Study, Lars Lind, Cecilia M Lindgren, Ruth J F Loos, Mary Ann Lukas, Leo-Pekka Lyytikäinen, Anubha Mahajan, Pamela R Matias-Garcia, Christa Meisinger, Thomas Meitinger, Olle Melander, Yuri Milaneschi, Pashupati P Mishra, Nina Mononen, Andrew P Morris, Josyf C Mychaleckyj, Girish N Nadkarni, Mariko Naito, Masahiro Nakatochi, Mike A Nalls, Matthias Nauck, Kjell Nikus, Boting Ning, Ilja M Nolte, Teresa Nutile, Michelle L O'Donoghue, Jeffrey O'Connell, Isleifur Olafsson, Marju Orho-Melander, Afshin Parsa, Sarah A Pendergrass, Brenda W J H Penninx, Mario Pirastu, Michael H Preuss, Bruce M Psaty, Laura M Raffield, Olli T Raitakari, Myriam Rheinberger, Kenneth M Rice, Federica Rizzi, Alexander R Rosenkranz, Peter Rossing, Jerome I Rotter, Daniela Ruggiero, Kathleen A Ryan, Charumathi Sabanayagam, Erika Salvi, Helena Schmidt, Reinhold Schmidt, Markus Scholz, Ben Schöttker, Christina-Alexandra Schulz, Sanaz Sedaghat, Christian M Shaffer, Karsten B Sieber, Xueling Sim, Mario Sims, Harold Snieder, Kira J Stanzick, Unnur Thorsteinsdottir, Hannah Stocker, Konstantin Strauch, Heather M Stringham, Patrick Sulem, Silke Szymczak, Kent D Taylor, Chris H L Thio, Johanne Tremblay, Simona Vaccargiu, Pim Van Der Harst, Peter J Van Der Most, Niek Verweij, Uwe Völker, Kenji Wakai, Melanie Waldenberger, Lars Wallentin, Stefan Wallner, Judy Wang, Dawn M Waterworth, Harvey D White, Cristen J Willer, Tien-Yin Wong, Mark Woodward, Qiong Yang, Laura M Yerges-Armstrong, Martina Zimmermann, Alan B Zonderman, Tobias Bergler, Kari Stefansson, Carsten A Böger, Cristian Pattaro, Anna Köttgen, Florian Kronenberg, Iris M Heid Sep 2022

Genetic Loci And Prioritization Of Genes For Kidney Function Decline Derived From A Meta-Analysis Of 62 Longitudinal Genome-Wide Association Studies, Mathias Gorski, Humaira Rasheed, Alexander Teumer, Laurent F Thomas, Sarah E Graham, Gardar Sveinbjornsson, Thomas W Winkler, Felix Günther, Klaus J Stark, Jin-Fang Chai, Bamidele O Tayo, Matthias Wuttke, Yong Li, Adrienne Tin, Tarunveer S Ahluwalia, Johan Ärnlöv, Bjørn Olav Åsvold, Stephan J L Bakker, Bernhard Banas, Nisha Bansal, Mary L Biggs, Ginevra Biino, Michael Böhnke, Eric Boerwinkle, Erwin P Bottinger, Hermann Brenner, Ben Brumpton, Robert J Carroll, Layal Chaker, John Chalmers, Miao-Li Chee, Miao-Ling Chee, Ching-Yu Cheng, Audrey Y Chu, Marina Ciullo, Massimiliano Cocca, James P Cook, Josef Coresh, Daniele Cusi, Martin H De Borst, Frauke Degenhardt, Kai-Uwe Eckardt, Karlhans Endlich, Michele K Evans, Mary F Feitosa, Andre Franke, Sandra Freitag-Wolf, Christian Fuchsberger, Piyush Gampawar, Ron T Gansevoort, Mohsen Ghanbari, Sahar Ghasemi, Vilmantas Giedraitis, Christian Gieger, Daniel F Gudbjartsson, Stein Hallan, Pavel Hamet, Asahi Hishida, Kevin Ho, Edith Hofer, Bernd Holleczek, Hilma Holm, Anselm Hoppmann, Katrin Horn, Nina Hutri-Kähönen, Kristian Hveem, Shih-Jen Hwang, M Arfan Ikram, Navya Shilpa Josyula, Bettina Jung, Mika Kähönen, Irma Karabegović, Chiea-Chuen Khor, Wolfgang Koenig, Holly Kramer, Bernhard K Krämer, Brigitte Kühnel, Johanna Kuusisto, Markku Laakso, Leslie A Lange, Terho Lehtimäki, Man Li, Wolfgang Lieb, Lifelines Cohort Study, Lars Lind, Cecilia M Lindgren, Ruth J F Loos, Mary Ann Lukas, Leo-Pekka Lyytikäinen, Anubha Mahajan, Pamela R Matias-Garcia, Christa Meisinger, Thomas Meitinger, Olle Melander, Yuri Milaneschi, Pashupati P Mishra, Nina Mononen, Andrew P Morris, Josyf C Mychaleckyj, Girish N Nadkarni, Mariko Naito, Masahiro Nakatochi, Mike A Nalls, Matthias Nauck, Kjell Nikus, Boting Ning, Ilja M Nolte, Teresa Nutile, Michelle L O'Donoghue, Jeffrey O'Connell, Isleifur Olafsson, Marju Orho-Melander, Afshin Parsa, Sarah A Pendergrass, Brenda W J H Penninx, Mario Pirastu, Michael H Preuss, Bruce M Psaty, Laura M Raffield, Olli T Raitakari, Myriam Rheinberger, Kenneth M Rice, Federica Rizzi, Alexander R Rosenkranz, Peter Rossing, Jerome I Rotter, Daniela Ruggiero, Kathleen A Ryan, Charumathi Sabanayagam, Erika Salvi, Helena Schmidt, Reinhold Schmidt, Markus Scholz, Ben Schöttker, Christina-Alexandra Schulz, Sanaz Sedaghat, Christian M Shaffer, Karsten B Sieber, Xueling Sim, Mario Sims, Harold Snieder, Kira J Stanzick, Unnur Thorsteinsdottir, Hannah Stocker, Konstantin Strauch, Heather M Stringham, Patrick Sulem, Silke Szymczak, Kent D Taylor, Chris H L Thio, Johanne Tremblay, Simona Vaccargiu, Pim Van Der Harst, Peter J Van Der Most, Niek Verweij, Uwe Völker, Kenji Wakai, Melanie Waldenberger, Lars Wallentin, Stefan Wallner, Judy Wang, Dawn M Waterworth, Harvey D White, Cristen J Willer, Tien-Yin Wong, Mark Woodward, Qiong Yang, Laura M Yerges-Armstrong, Martina Zimmermann, Alan B Zonderman, Tobias Bergler, Kari Stefansson, Carsten A Böger, Cristian Pattaro, Anna Köttgen, Florian Kronenberg, Iris M Heid

Faculty, Staff and Student Publications

Estimated glomerular filtration rate (eGFR) reflects kidney function. Progressive eGFR-decline can lead to kidney failure, necessitating dialysis or transplantation. Hundreds of loci from genome-wide association studies (GWAS) for eGFR help explain population cross section variability. Since the contribution of these or other loci to eGFR-decline remains largely unknown, we derived GWAS for annual eGFR-decline and meta-analyzed 62 longitudinal studies with eGFR assessed twice over time in all 343,339 individuals and in high-risk groups. We also explored different covariate adjustment. Twelve genome-wide significant independent variants for eGFR-decline unadjusted or adjusted for eGFR-baseline (11 novel, one known for this phenotype), including nine …


Major Pathologic Response And Prognostic Score Predict Survival In Patients With Lung Cancer Receiving Neoadjuvant Chemotherapy, Apar Pataer, Annikka Weissferdt, Arlene M Correa, Ara A Vaporciyan, Boris Sepesi, John V Heymach, Sabina Berezowska, Tina Cascone, Stephen G Swisher Sep 2022

Major Pathologic Response And Prognostic Score Predict Survival In Patients With Lung Cancer Receiving Neoadjuvant Chemotherapy, Apar Pataer, Annikka Weissferdt, Arlene M Correa, Ara A Vaporciyan, Boris Sepesi, John V Heymach, Sabina Berezowska, Tina Cascone, Stephen G Swisher

Faculty, Staff and Student Publications

INTRODUCTION: Complete pathologic response (CPR) is an acceptable surrogate for survival in clinical trials but it occurs infrequently in patients with NSCLC receiving neoadjuvant chemotherapy (NCT). Therefore, we studied the impact of major pathologic response (MPR) for predicting survival of patients with NSCLC receiving NCT. We also tested a newly reported scoring system-the prognostic score (PRSC)-which combines T category, lymph node status, and MPR status.

METHODS: We analyzed CPR and MPR, defined as 0% and less than or equal to 10% viable tumor cells, respectively, in 339 patients with NSCLC with various histologic types who had been treated with NCT …


Tumor Immune Microenvironment Changes By Multiplex Immunofluorescence Staining In A Pilot Study Of Neoadjuvant Talazoparib For Early-Stage Breast Cancer Patients With A Hereditary Brca Mutation, Tapsi Kumar, Evie Hobbs, Fei Yang, Jeffrey T Chang, Alejandro Contreras, Edwin Roger Parra Cuentas, Haven Garber, Sanghoon Lee, Yiling Lu, Marion E Scoggins, Beatriz E Adrada, Gary J Whitman, Banu K Arun, Elizabeth A Mittendorf, Jennifer K Litton Sep 2022

Tumor Immune Microenvironment Changes By Multiplex Immunofluorescence Staining In A Pilot Study Of Neoadjuvant Talazoparib For Early-Stage Breast Cancer Patients With A Hereditary Brca Mutation, Tapsi Kumar, Evie Hobbs, Fei Yang, Jeffrey T Chang, Alejandro Contreras, Edwin Roger Parra Cuentas, Haven Garber, Sanghoon Lee, Yiling Lu, Marion E Scoggins, Beatriz E Adrada, Gary J Whitman, Banu K Arun, Elizabeth A Mittendorf, Jennifer K Litton

Faculty, Staff and Student Publications

PURPOSE: The immunological profile of early-stage breast cancer treated with neoadjuvant PARP inhibitors has not been described. The aim of this study was to delineate the changes in the tumor immune microenvironment (TiME) induced by talazoparib.

PATIENTS AND METHODS: Patients with operable germline BRCA1/2 pathogenic variant (gBRCA1/2+) breast cancer were enrolled in a feasibility study of neoadjuvant talazoparib. Thirteen patients who received 8 weeks of neoadjuvant talazoparib were available for analysis, including 11 paired pre- and post-talazoparib core biopsies. Treatment-related changes in tumor-infiltrating lymphocytes were examined and immune cell phenotypes and their spatial distribution in the TiME were identified and …


Confirming Subarachnoid Hemorrhage Induction In The Endovascular Puncture Mouse Model, Ari Dienel, Sung-Ha Hong, Jose Guzman, Kumar T Peeyush, Spiros L Blackburn, Devin W Mcbride Sep 2022

Confirming Subarachnoid Hemorrhage Induction In The Endovascular Puncture Mouse Model, Ari Dienel, Sung-Ha Hong, Jose Guzman, Kumar T Peeyush, Spiros L Blackburn, Devin W Mcbride

Faculty, Staff and Student Publications

Background and purpose: Experimental studies of subarachnoid hemorrhage (SAH) using the endovascular perforation model routinely use either cerebral blood flow (CBF) or intracranial pressure (ICP) monitoring to confirm SAH induction. We designed this study to test the hypothesis that contralateral CBF is a better marker of SAH induction than ipsilateral CBF.

Methods: Sixty-eight adult C57BL/6J mice were subjected to endovascular perforation. Mice were monitored using laser Doppler (for relative CBF) or ICP probes.

Results: The ipsilateral CBF significantly decreased prior to ICP rising. However, reduction of the CBF in the contralateral hemisphere occurred at the same time as the rise …


Idh1 Prr32h Ctdna And D-2-Hydroxyglutarate As Csf Biomarkers In Patients With Idh-Mutant Gliomas, Yoko Fujita, Luis Nunez-Rubiano, Antonio Dono, Allison Bellman, Mauli Shah, Juan C Rodriguez, Vasanta Putluri, Abu Hena Mostafa Kamal, Nagireddy Putluri, Roy F Riascos, Jay-Jiguang Zhu, Yoshua Esquenazi, Leomar Y Ballester Sep 2022

Idh1 Prr32h Ctdna And D-2-Hydroxyglutarate As Csf Biomarkers In Patients With Idh-Mutant Gliomas, Yoko Fujita, Luis Nunez-Rubiano, Antonio Dono, Allison Bellman, Mauli Shah, Juan C Rodriguez, Vasanta Putluri, Abu Hena Mostafa Kamal, Nagireddy Putluri, Roy F Riascos, Jay-Jiguang Zhu, Yoshua Esquenazi, Leomar Y Ballester

Faculty, Staff and Student Publications

INTRODUCTION: We aimed to evaluate IDH1 p.R132H mutation and 2-hydroxyglutarate (2HG) in cerebrospinal fluid (CSF) as biomarkers for patients with IDH-mutant gliomas.

METHODS: CSF was collected from patients with infiltrating glioma, and 2HG levels were measured by liquid chromatography-mass spectrometry. IDH1 p.R132H mutant allele frequency (MAF) in CSF-ctDNA was measured by digital droplet PCR (ddPCR). Tumor volume was measured from standard-of-care magnetic resonance images.

RESULTS: The study included 48 patients, 6 with IDH-mutant and 42 with IDH-wildtype gliomas, and 57 samples, 9 from the patients with IDH-mutant and 48 from the patients with IDH-wildtype gliomas. ctDNA was detected in 7 …


Plasmonic Gadolinium Oxide Nanomatryoshkas: Bifunctional Magnetic Resonance Imaging Enhancers For Photothermal Cancer Therapy, Luke Henderson, Oara Neumann, Yara Kadria-Vili, Burak Gerislioglu, James Bankson, Peter Nordlander, Naomi J Halas Sep 2022

Plasmonic Gadolinium Oxide Nanomatryoshkas: Bifunctional Magnetic Resonance Imaging Enhancers For Photothermal Cancer Therapy, Luke Henderson, Oara Neumann, Yara Kadria-Vili, Burak Gerislioglu, James Bankson, Peter Nordlander, Naomi J Halas

Faculty, Staff and Student Publications

Nanoparticle-assisted laser-induced photothermal therapy (PTT) is a promising method for cancer treatment; yet, visualization of nanoparticle uptake and photothermal response remain a critical challenge. Here, we report a magnetic resonance imaging-active nanomatryoshka (Gd2O3-NM), a multilayered (Au core/Gd2O3 shell/Au shell) sub-100 nm nanoparticle capable of combining T1 MRI contrast with PTT. This bifunctional nanoparticle demonstrates an r1 of 1.28 × 108 mM-1 s-1, an MRI contrast enhancement per nanoparticle sufficient for T1 imaging in addition to tumor ablation. Gd2O3-NM also shows excellent stability in an acidic environment, retaining 99% of the internal Gd(3). This report details the synthesis and characterization of …


Automation Of Radiation Treatment Planning For Rectal Cancer, Kai Huang, Prajnan Das, Adenike M Olanrewaju, Carlos Cardenas, David Fuentes, Lifei Zhang, Donald Hancock, Hannah Simonds, Dong Joo Rhee, Sam Beddar, Tina M Briere, Laurence Court Sep 2022

Automation Of Radiation Treatment Planning For Rectal Cancer, Kai Huang, Prajnan Das, Adenike M Olanrewaju, Carlos Cardenas, David Fuentes, Lifei Zhang, Donald Hancock, Hannah Simonds, Dong Joo Rhee, Sam Beddar, Tina M Briere, Laurence Court

Faculty, Staff and Student Publications

PURPOSE: To develop an automated workflow for rectal cancer three-dimensional conformal radiotherapy (3DCRT) treatment planning that combines deep learning (DL) aperture predictions and forward-planning algorithms.

METHODS: We designed an algorithm to automate the clinical workflow for 3DCRT planning with field aperture creations and field-in-field (FIF) planning. DL models (DeepLabV3+ architecture) were trained, validated, and tested on 555 patients to automatically generate aperture shapes for primary (posterior-anterior [PA] and opposed laterals) and boost fields. Network inputs were digitally reconstructed radiographs, gross tumor volume (GTV), and nodal GTV. A physician scored each aperture for 20 patients on a 5-point scale (>3 …


In-Situ Measurements Of Temperature And Emissivity During Msw Combustion Using Spectral Analysis And Multispectral Imaging Processing, Shu Zheng, Weiguang Cai, Ran Sui, Zixue Luo, Qiang Lu Sep 2022

In-Situ Measurements Of Temperature And Emissivity During Msw Combustion Using Spectral Analysis And Multispectral Imaging Processing, Shu Zheng, Weiguang Cai, Ran Sui, Zixue Luo, Qiang Lu

Mechanical and Aerospace Engineering Faculty Research & Creative Works

By using a novel multispectral imaging technology, the 2-D distributions of flame temperature and emissivity were measured in a 16 MW incinerator to co-fire municipal solid waste (MSW) and municipal sludge. A way to establish the relationship between the multispectral flame images and the temperature was proposed by combing the Newton iteration method and Hottel emissivity model. The results showed that the measured temperatures at different locations varied by 31.25% with a fixed steam evaporation rate, and 11.76% with different steam evaporation rates at a given port. The temperatures and emissivities decreased at upper locations due to the lower local …


Juvenile Report, September 2022, Tennessee. Department Of Correction. Sep 2022

Juvenile Report, September 2022, Tennessee. Department Of Correction.

Juvenile Reports

No abstract provided.


Tennessee Felon Population Update, September 2022, Tennessee. Department Of Correction. Sep 2022

Tennessee Felon Population Update, September 2022, Tennessee. Department Of Correction.

Felon Population Reports

No abstract provided.


Together With Tosha Newsletter, September 2022, Tennessee. Department Of Labor & Workforce Development. Sep 2022

Together With Tosha Newsletter, September 2022, Tennessee. Department Of Labor & Workforce Development.

TOSHA Newsletter

No abstract provided.


Tennessee Labor Market Report, September 2022, Facts About U.S. Veterans, Tennessee. Department Of Labor & Workforce Development. Sep 2022

Tennessee Labor Market Report, September 2022, Facts About U.S. Veterans, Tennessee. Department Of Labor & Workforce Development.

Labor Market Reports

No abstract provided.


Natural Language Processing For Novel Writing, Leqing Qu, Okan Ersoy Sep 2022

Natural Language Processing For Novel Writing, Leqing Qu, Okan Ersoy

Department of Electrical and Computer Engineering Technical Reports

No abstract provided.


Community-Building, Empowering Voices And Brave Spaces Through Lis Professional Conferences, Jennifer Masunaga, Jessea Young, Aisha Conner-Gaten, Nataly Blas Sep 2022

Community-Building, Empowering Voices And Brave Spaces Through Lis Professional Conferences, Jennifer Masunaga, Jessea Young, Aisha Conner-Gaten, Nataly Blas

Librarian Publications & Presentations

This chapter centers on the experience of four Black, Indigenous, people of color (BIPOC) academic librarians who conceived, planned, and executed a local one-day in-person summit for BIPOC information workers in 2018 and an online version in 2021. The POCinLIS Summit celebrated and uplifted BIPOC information workers from the public, private and academic fields of LIS. Since libraries were established, information systems and institutions have prioritized and normalized whiteness. To amplify and bolster BIPOC siloed in their work, the Summit sought to create counterspaces unaffiliated with a professional organization or traditional LIS conference spaces. To address why BIPOC-centered programs are …


Regulatory Compliance Of Labels And Product Information Leaflets For Medicines Distributed In The Private Sector In South Sudan, Stephen Mawa, Zita Ekeocha, Stephen Byrn, Kari Clase Sep 2022

Regulatory Compliance Of Labels And Product Information Leaflets For Medicines Distributed In The Private Sector In South Sudan, Stephen Mawa, Zita Ekeocha, Stephen Byrn, Kari Clase

BIRS Africa Technical Report Papers

Patient information leaflets (PILs) and labels are important for rational use of medicines as they provide additional information for patients on the medicines dispensed to them. In developing countries, this potential cannot be fully harnessed unless manufacturers provide medicines with labels and PILs that meet regulatory standards for content and user-friendliness. In South Sudan, it is not known if manufacturers uphold standards of these labels and PILs once their products are approved for distribution in the country.

This study explored the degree to which medicines distributed in South Sudan comply with regulatory requirements for labels and PILs. A cross-sectional survey …


Development Of An Assessment Tool For Good Distribution Practice For A Regulatory Agency In West Africa, Ukamaka Gladys Okafor, Zita Ekeocha, Stephen Byrn, Kari Clase, Solomon Shiihii Sep 2022

Development Of An Assessment Tool For Good Distribution Practice For A Regulatory Agency In West Africa, Ukamaka Gladys Okafor, Zita Ekeocha, Stephen Byrn, Kari Clase, Solomon Shiihii

BIRS Africa Technical Report Papers

Good Distribution Practice (GDP) refers to the regulatory guidelines governing the wholesale and distribution of medicinal products to ensure that their quality and integrity are maintained throughout the supply chain from the manufacturer to the end users. A standard assessment tool for GDP is necessary in order to conduct a robust assessment on GDP on pharmaceutical industries. The observed agency’s policy and operational documents in addition to GDP Guidelines from World Health Organization and related organizations from various countries were reviewed. The observed Regulatory Agency does not have a separate assessment tool for GDP inspection. Few core GDP parameters are …


50 Tips For Traveling Responsibly, Ailin Fei, Jonathon Day Sep 2022

50 Tips For Traveling Responsibly, Ailin Fei, Jonathon Day

Tourism Insights

Travel is one of the great things in life. Nothing beats the thrill of seeing new things, exploring new cultures or experiencing things you just can't do at home.

Despite the benefits of travel, more people are becoming concerned that our travel is having negative impacts on the people and places we visit. We worry that we will love our special places to death. In fact, recent research conducted by Booking.com shows that "83% of global travelers think sustainable travel is vital" and of the more than 29,000 travelers surveyed across 30 countries, 72% believe that we need to act …


Synthetic Aperture Radar Imaging, Srivatsan Ravichandran, Okan Ersoy Sep 2022

Synthetic Aperture Radar Imaging, Srivatsan Ravichandran, Okan Ersoy

Department of Electrical and Computer Engineering Technical Reports

Simulation programs are used to locate the positions of the input target points and generate a 2D SAR image with the Range Migration Algorithm. Using the same methodology, we can create a scene geometry using the concept of Point cloud and run the simulation program to generate raw SAR data.


Dicamba Residue Persistence In Processing Tomato, Stephen L. Meyers, Jeanine Arana, Brandi C. Woolam, Nathaly Vargas, Laura Rodriguez, Luz Cardona Sep 2022

Dicamba Residue Persistence In Processing Tomato, Stephen L. Meyers, Jeanine Arana, Brandi C. Woolam, Nathaly Vargas, Laura Rodriguez, Luz Cardona

Department of Horticulture & Landscape Architecture Faculty Publications

There is zero tolerance for dicamba and dicamba metabolite residue in tomato (Solanum lycopersicum L.) fruit following exposure to dicamba. Field trials were conducted in 2020 and 2021 to determine the persistence of dicamba and metabolite (5-hydroxy dicamba and 3,6-dichlorosalicylic acid [DCSA]) residue in processing tomato shoots and fruits. Dicamba was applied 49 d after transplanting at 0, 0.53, 5.3, and 53 g ae ha−1. Tomato plants were harvested 5, 10, 20, 40, and 61 d after treatment (DAT). No 5-hydroxy dicamba was recovered from any sample. In 2020, the DCSA metabolite was detected from tomato shoot tissue when dicamba …


Unclean Patents, Sean B. Seymore Sep 2022

Unclean Patents, Sean B. Seymore

Vanderbilt Law School Faculty Publications

The doctrine of unclean hands is perhaps the most storied affirmative defense in civil cases. It allows a court to dismiss a lawsuit without reaching the merits if the patent owner (patentee) engaged in misconduct related to the claim being asserted. In patent law, the Supreme Court has stated that the doctrine is of "paramount interest" given the nature of the patent bargain between the inventor and the public. Nonetheless, unclean hands has been a relatively dormant defense in patent cases, other than in the specific context of patent procurement at the Patent Office (where it has evolved into the …


Re-Presenting The Un-Presentable: Annie Ernaux’S "L’Évènement" And Cristian Mungiu’S "4 Months, 3 Weeks, And Two Days", Victoria Tomasulo Sep 2022

Re-Presenting The Un-Presentable: Annie Ernaux’S "L’Évènement" And Cristian Mungiu’S "4 Months, 3 Weeks, And Two Days", Victoria Tomasulo

Publications and Research

Situating Annie Ernaux’s L’évènement and Cristian Mungiu’s 4 Months, 3 Weeks, and 2 Days in a reproductive justice framework, I argue that both the memoir and the film contribute to working-class historiographies by documenting backstreet abortion in times and places where it was heavily criminalized: 1960s France and Communist Romania. Committed to a working-class aesthetic with roots in neorealism, Ernaux and Mungiu focus singularly on an event once deemed unrepresentable in literature and cinema. Drawing upon the distinction made between empathy and “rational compassion” made by Paul Bloom in Against Empathy (2016), as well as from Kelly Oliver’s Witnessing: Beyond …


A Student-Designed Learning Management System: A Mixed-Methods Analysis Of Undergraduate Student Ideas For Improving The Lms, Erin P. Manott Morris Sep 2022

A Student-Designed Learning Management System: A Mixed-Methods Analysis Of Undergraduate Student Ideas For Improving The Lms, Erin P. Manott Morris

Dissertations

Learning management systems (LMS) are digital tools used to comprehensively deliver education in various settings, including higher education. Using LMSs has been shown to support learner-centered instructional practices and, when used well, to support positive learning outcomes in students. While previous research has examined student use and satisfaction with an LMS, little research has explored student perceptions regarding LMS design. The study evaluated undergraduate students’ perceptions and opinions of an LMS’s design. The study also sought to compare students’ attitudes regarding their LMS during pre-COVID and following the pandemic’s onset. Forty-five students participated in a survey, and three participated in …