Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 656611 - 656640 of 5153996

Full-Text Articles in Entire DC Network

Adult Day Services In Maine: Benefits, Challenges, And Opportunities, Elizabeth Gattine Jd, Eileen Griffin Jd, Kimberly I. Snow Mhsa, Ba Sep 2022

Adult Day Services In Maine: Benefits, Challenges, And Opportunities, Elizabeth Gattine Jd, Eileen Griffin Jd, Kimberly I. Snow Mhsa, Ba

Disability & Aging

In Maine and nationally, adult day services tend to be underfunded and underutilized compared to other types of long term services and supports (LTSS). In part, investment in adult day services is hampered by a lack of standardized data collection and limited research on issues of accessibility, cost-effectiveness, and the impact of adult day services on the broader health system. Lack of uniformity in state regulatory frameworks for licensing, program design, service delivery, and other administrative requirements further complicates cross-state comparisons. Considering these limitations, a key goal of this report is to provide a more detailed and comprehensive understanding of …


Montana Voices Amplified: My Perspective: What Just Happened? Audio Description Can Answer That, Sara Streeter, University Of Montana Rural Institute Sep 2022

Montana Voices Amplified: My Perspective: What Just Happened? Audio Description Can Answer That, Sara Streeter, University Of Montana Rural Institute

Independent Living and Community Participation

Sara Streeter discusses the importance of audio description for people with vision loss when watching a movie or play.


The Rise And Fall Of Group Libel: The Forgotten Campaign For Hate Speech Laws, Samantha Barbas Sep 2022

The Rise And Fall Of Group Libel: The Forgotten Campaign For Hate Speech Laws, Samantha Barbas

Journal Articles

It is well-known that there is no “hate speech” law in the United States. This has been criticized, especially given the existence of robust hate speech laws in other nations. The absence of hate speech laws in American law has been attributed to legal, cultural, and historical factors, including speech protective First Amendment jurisprudence and long-standing skepticism of group reputation as an interest worthy of legal protection.

This Article presents another reason for the absence of hate speech laws in America: the failure of a large-scale social movement in the 1940s to pass hate speech laws or “group libel” laws, …


Screening Families In Primary Care For Social And Economic Needs: Patients’ Urgency And Activation For Social Care Navigation, Sarah D. Ronis, Marie Masotya, Kurt C. Stange Sep 2022

Screening Families In Primary Care For Social And Economic Needs: Patients’ Urgency And Activation For Social Care Navigation, Sarah D. Ronis, Marie Masotya, Kurt C. Stange

Faculty Scholarship

Introduction: Social determinants of health (SDoH) screening and intervention in primary care aim to alleviate adverse influences on health, but its efficacy may be diluted when offered supports are not well matched to families’ desire for such services. The purpose of this prospective cohort study was to provide guidance to social care navigation teams regarding which families would be most likely to make use of services. Methods: Analysis of registry data collected in April 1–September 30, 2021 from a social care navigation program embedded in a medical home was conducted. Multivariable regression models explored (1) whether family-reported urgency of needs, …


Tct-70 Clinical Predictors Of Patients Requiring Prolonged Mechanical Circulatory Support After High-Risk Pci, Mir B. Basir, Alejandro Lemor, Yanru Li, Bjorn Redfors, Alexander Truesdell, Aditya Bharadwaj, Amir Kaki, David Wohns, Perwaiz Meraj, Ramesh Daggubati, Cindy Grines, William O'Neill, Jeffrey Moses Sep 2022

Tct-70 Clinical Predictors Of Patients Requiring Prolonged Mechanical Circulatory Support After High-Risk Pci, Mir B. Basir, Alejandro Lemor, Yanru Li, Bjorn Redfors, Alexander Truesdell, Aditya Bharadwaj, Amir Kaki, David Wohns, Perwaiz Meraj, Ramesh Daggubati, Cindy Grines, William O'Neill, Jeffrey Moses

Cardiology Meeting Abstracts

Background: There are limited data on predicative parameters to guide weaning after high-risk percutaneous coronary intervention (HRPCI) requiring mechanical circulatory support (MCS).

Methods: Patients enrolled into the prospective, multicenter, adjudicated, PROTECT III study who underwent HRPCI with Impella MCS were evaluated. Patients who required prolonged MCS, defined as requiring ongoing MCS beyond the index PCI, were compared to those in whom MCS was successfully weaned and explanted after index PCI.

Results: 1,196 patients were treated at 46 sites between 2017 and 2020. 207 patients (17%) required prolonged support with a mean duration of support of 27.3 ± 34.2 compared to …


Impact Of Covid-19 Pandemic On Tavr Activity: A Worldwide Registry, Xavier Armario, Jennifer Carron, Mohamed Abdel-Wahab, Didier Tchetche, Sabine Bleiziffer, Thierry Lefevre, Thomas Modine, Alexander Wolf, Thomas Pilgrim, Pedro Villablanca, Michael Cunnington, Nicolas Van Mieghem, Christian Hengstenberg, Lars Sondergaard, Martin Swaans, Bernard Prendergast, Marco Barbanti, John Webb, Neal Uren, Jon Resar, Mao Chen, David Hildick-Smith, Mark Spence, David Zweiker, Rodrigo Bagur, Hospital De Cruz, Flavio Ribichini, Duk-Woo Park, Pablo Codner, Joanna Wykrzykowska, Matjaz Bunc, Rodrigo Estevez-Loureiro, Karl Poon, Matthias Götberg, Hüseyin Ince, Azeem Latib, Erik Packer, Marco Angelillis, Yusuke Kobari, Luis Nombela-Franco, Yingqiang Guo, Mikko Savontaus, Amr A. Arafat, Chad Kliger, David Roy, Béla Merkely, Mariana Silva, Jonathon White, Masanori Yamamoto, Pedro Carrilho Ferreira, Stefan Toggweiler, Yohei Ohno, Ines Rodrigues, Soledad Ojeda, Vasileios Voudris, Marek Grygier, Khaled Almerri, Ignacio Cruz-Gonzalez, Viliam Fridrich, Jose De La Torre Hernandez, Nicolo Piazza, Stephane Noble, Dabit Arzamendi, Ibrahim H. Kurt, Johan Bosmans, Martins Erglis, Ivan Casserly, Fadi Sawaya, Ravinay Bhindi, Joelle Kefer, Wei-Hsian Yin, Liesbeth Rosseel, Hyo-Soo Kim, Stephen O'Connor, Farrel Hellig, Matias Sztejfman, Oscar Mendiz, Robert Xuereb, Fabio Brito Jr, Vilhelmas Bajoras, Mohammed Balghith, Michael Kang-Yin Lee, Guering Eid-Lidt, Bert Vandeloo, Vinicius Vaz, Mirvat Alasnag, Gian Paolo Ussia, Jorge Mayol, Gennaro Sardella, Wacin Buddhari, Hsien-Li Kao, Antonio Dager, Apostolos Tzikas, Ahmad Edris, Luis Gutierrez, Eduardo Arias, Mehmet Erturk, César Nicolás Conde Vela, Darko Boljevic, Adolfo Ferrero Guadagnoli, Ahmed Elguindy, Luciano Santos, Luis Perez, Gabriel Maluenda, Ali Riza Akyüz, Imad Alhaddad, Haitham Amin, So Chak Yu, Arif Alnooryani, Juan Albistur, Quang Nguyen, Darren Mylotte Sep 2022

Impact Of Covid-19 Pandemic On Tavr Activity: A Worldwide Registry, Xavier Armario, Jennifer Carron, Mohamed Abdel-Wahab, Didier Tchetche, Sabine Bleiziffer, Thierry Lefevre, Thomas Modine, Alexander Wolf, Thomas Pilgrim, Pedro Villablanca, Michael Cunnington, Nicolas Van Mieghem, Christian Hengstenberg, Lars Sondergaard, Martin Swaans, Bernard Prendergast, Marco Barbanti, John Webb, Neal Uren, Jon Resar, Mao Chen, David Hildick-Smith, Mark Spence, David Zweiker, Rodrigo Bagur, Hospital De Cruz, Flavio Ribichini, Duk-Woo Park, Pablo Codner, Joanna Wykrzykowska, Matjaz Bunc, Rodrigo Estevez-Loureiro, Karl Poon, Matthias Götberg, Hüseyin Ince, Azeem Latib, Erik Packer, Marco Angelillis, Yusuke Kobari, Luis Nombela-Franco, Yingqiang Guo, Mikko Savontaus, Amr A. Arafat, Chad Kliger, David Roy, Béla Merkely, Mariana Silva, Jonathon White, Masanori Yamamoto, Pedro Carrilho Ferreira, Stefan Toggweiler, Yohei Ohno, Ines Rodrigues, Soledad Ojeda, Vasileios Voudris, Marek Grygier, Khaled Almerri, Ignacio Cruz-Gonzalez, Viliam Fridrich, Jose De La Torre Hernandez, Nicolo Piazza, Stephane Noble, Dabit Arzamendi, Ibrahim H. Kurt, Johan Bosmans, Martins Erglis, Ivan Casserly, Fadi Sawaya, Ravinay Bhindi, Joelle Kefer, Wei-Hsian Yin, Liesbeth Rosseel, Hyo-Soo Kim, Stephen O'Connor, Farrel Hellig, Matias Sztejfman, Oscar Mendiz, Robert Xuereb, Fabio Brito Jr, Vilhelmas Bajoras, Mohammed Balghith, Michael Kang-Yin Lee, Guering Eid-Lidt, Bert Vandeloo, Vinicius Vaz, Mirvat Alasnag, Gian Paolo Ussia, Jorge Mayol, Gennaro Sardella, Wacin Buddhari, Hsien-Li Kao, Antonio Dager, Apostolos Tzikas, Ahmad Edris, Luis Gutierrez, Eduardo Arias, Mehmet Erturk, César Nicolás Conde Vela, Darko Boljevic, Adolfo Ferrero Guadagnoli, Ahmed Elguindy, Luciano Santos, Luis Perez, Gabriel Maluenda, Ali Riza Akyüz, Imad Alhaddad, Haitham Amin, So Chak Yu, Arif Alnooryani, Juan Albistur, Quang Nguyen, Darren Mylotte

Cardiology Meeting Abstracts

Background: The COVID-19 pandemic had a considerable impact on the provision of structural heart intervention worldwide. Our objectives were: 1) to assess the impact of the COVID-19 pandemic on transcatheter aortic valve replacement (TAVR) activity globally; and 2) to determine the differences in the impact according to geographic region and the demographic, development, and economic status of diverse international health care systems.

Methods: We developed a multinational registry of global TAVR activity and invited individual TAVR sites to submit TAVR implant data before and during the COVID-19 pandemic. Specifically, the number of TAVR procedures performed monthly from January 2019 to …


Tct-374 Structural Heart Intraprocedural Versus Nonprocedural Transesophageal Echocardiography: A Quantitative Analysis Of Complexity, Ayman Alsaadi, Ali H. Ghandour, Abel Ignatius, Alexandra Martin, James Lee, Bobak T. Rabbani, Bryan Zweig, Sachin Parikh, Pedro Villablanca, Carl P. Wilson, Tiberio Frisoli, Brian P. O'Neill, William O'Neill, Dee Dee Wang Sep 2022

Tct-374 Structural Heart Intraprocedural Versus Nonprocedural Transesophageal Echocardiography: A Quantitative Analysis Of Complexity, Ayman Alsaadi, Ali H. Ghandour, Abel Ignatius, Alexandra Martin, James Lee, Bobak T. Rabbani, Bryan Zweig, Sachin Parikh, Pedro Villablanca, Carl P. Wilson, Tiberio Frisoli, Brian P. O'Neill, William O'Neill, Dee Dee Wang

Cardiology Meeting Abstracts

Background: Transesophageal echocardiography (TEE) is an essential tool in many structural heart procedures, such as transcatheter mitral valve edge-to-edge repair (TEER). Interventional procedural TEE requires a unique skill set. This study aims to evaluate the complexity of interventional structural heart TEE used to guide TEER compared with standard of care (SOC) TEE studies performed at a single center.

Methods: A retrospective case-control analysis was performed of 200 patients who underwent TEE in the Henry Ford Health System. One hundred cases of interventional TEE-guided TEER were compared with 100 controls of SOC TEE. Complexity was quantified by the total duration of …


Tct-353 Clinical Characteristics And Outcomes Of Alcohol Septal Ablation In The Era Of Transcatheter Valve Interventions, Samuel Gregerson, Shazil Mahmood, Collin Brooks, Pedro Engel Gonzalez, Pedro Villablanca, Tiberio Frisoli, James Lee, Dee Dee Wang, William O'Neill, Brian P. O'Neill Sep 2022

Tct-353 Clinical Characteristics And Outcomes Of Alcohol Septal Ablation In The Era Of Transcatheter Valve Interventions, Samuel Gregerson, Shazil Mahmood, Collin Brooks, Pedro Engel Gonzalez, Pedro Villablanca, Tiberio Frisoli, James Lee, Dee Dee Wang, William O'Neill, Brian P. O'Neill

Cardiology Meeting Abstracts

Background: Alcohol septal ablation (ASA) is an alternative to surgical myectomy for left ventricular outflow tract (LVOT) obstruction in HCM and pre-emptive before transcatheter mitral valve replacement (TMVR) to prevent LVOT obstruction. This study aimed to evaluate the procedural characteristics and outcomes of ASA in contemporary practice.

Methods: This was a single-center retrospective study of 137 patients undergoing ASA for HCM and TMVR at Henry Ford Hospital from January 2010 to August 2021. Patient/procedure characteristics and outcomes were assessed. The primary endpoint was an adverse composite of new pacemaker requirement (PPM), stroke, sustained ventricular tachycardia, resuscitated cardiac arrest, and all-cause …


Tct-66 Door To Impella Placement In Acute Coronary Syndrome Complicated By Cardiogenic Shock: An Updated Meta-Analysis, Mario Iannaccone, Luca Franchin, Ivan Hanson, Giacomo Boccuzzi, Mir B. Basir, Alexander Truesdell, William O'Neill Sep 2022

Tct-66 Door To Impella Placement In Acute Coronary Syndrome Complicated By Cardiogenic Shock: An Updated Meta-Analysis, Mario Iannaccone, Luca Franchin, Ivan Hanson, Giacomo Boccuzzi, Mir B. Basir, Alexander Truesdell, William O'Neill

Cardiology Meeting Abstracts

Background: The impact of time to hemodynamic support in acute myocardial infarction complicated by cardiogenic shock (AMICS) has yet to be defined. The aim of this meta-analysis was to evaluate the impact of timing of mechanical circulatory support (MCS) with Impella.

Methods: a systematic literature review and meta-analysis was conducted using PubMed and Cochrane databases. All studies reporting short-term mortality rates and timing of Impella insertion, pre vs during/post PCI, were included. Primary end point was short-term mortality (≤30 days), while secondary end pointswere midterm mortality, device-related bleeding and limb ischemia.

Results: Of 1,289 studies identified, 13 studies (6,810 patients; …


Tct-171 Predicting The Risk Of Perforation Requiring Pericardiocentesis In Chronic Total Occlusion Percutaneous Coronary Intervention: The Progress-Cto Pericardiocentesis Score, Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Rhian Davies, Jeremy Rier, Omer Goktekin, Sevket Gorgulu, Ahmed Elguindy, Raj Chandwaney, Mitul Patel, Dimitri Karmpaliotis, Jaikirshan Khatri, Farouc Jaffer, Paul Poommipanit, Bavana Rangan, Yader Sandoval, Basem Elbarouni, William Nicholson, Stephane Rinfret, Michail Koutouzis, Ioannis Tsiafoutis, Robert Yeh, M. Nicholas Burke, Salman Allana, Olga Mastrodemos, Emmanouil Brilakis Sep 2022

Tct-171 Predicting The Risk Of Perforation Requiring Pericardiocentesis In Chronic Total Occlusion Percutaneous Coronary Intervention: The Progress-Cto Pericardiocentesis Score, Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Rhian Davies, Jeremy Rier, Omer Goktekin, Sevket Gorgulu, Ahmed Elguindy, Raj Chandwaney, Mitul Patel, Dimitri Karmpaliotis, Jaikirshan Khatri, Farouc Jaffer, Paul Poommipanit, Bavana Rangan, Yader Sandoval, Basem Elbarouni, William Nicholson, Stephane Rinfret, Michail Koutouzis, Ioannis Tsiafoutis, Robert Yeh, M. Nicholas Burke, Salman Allana, Olga Mastrodemos, Emmanouil Brilakis

Cardiology Meeting Abstracts

Background: Estimating the risk for complications facilitates risk-benefit assessment and procedural planning in chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Methods: We analyzed the PROGRESS-CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention; NCT02061436) and created a risk score for pericardiocentesis. Patients with histories of coronary artery bypass graft surgery were excluded. Logistic regression prediction modeling was used to identify independently associated variables, and the model was internally validated with bootstrapping.

Results: Of the 7,672 CTO PCI cases performed between 2012 and 2022 at 40 centers, 83 (1.1%) required pericardiocentesis. The final prediction model identified predictors …


Tct-113 Predicting The Risk Of In-Hospital Major Adverse Cardiovascular Events In Chronic Total Occlusion Percutaneous Coronary Intervention: The Progress-Cto Mace Score, Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Rhian Davies, Jeremy Rier, Omer Goktekin, Sevket Gorgulu, Ahmed Elguindy, Raj Chandwaney, Mitul Patel, Dimitri Karmpaliotis, Jaikirshan Khatri, Farouc Jaffer, Paul Poommipanit, Bavana Rangan, Yader Sandoval, Basem Elbarouni, William Nicholson, Stephane Rinfret, Michail Koutouzis, Ioannis Tsiafoutis, Robert Yeh, M. Nicholas Burke, Salman Allana, Emmanouil Brilakis Sep 2022

Tct-113 Predicting The Risk Of In-Hospital Major Adverse Cardiovascular Events In Chronic Total Occlusion Percutaneous Coronary Intervention: The Progress-Cto Mace Score, Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Oleg Krestyaninov, Dmitrii Khelimskii, Rhian Davies, Jeremy Rier, Omer Goktekin, Sevket Gorgulu, Ahmed Elguindy, Raj Chandwaney, Mitul Patel, Dimitri Karmpaliotis, Jaikirshan Khatri, Farouc Jaffer, Paul Poommipanit, Bavana Rangan, Yader Sandoval, Basem Elbarouni, William Nicholson, Stephane Rinfret, Michail Koutouzis, Ioannis Tsiafoutis, Robert Yeh, M. Nicholas Burke, Salman Allana, Emmanouil Brilakis

Cardiology Meeting Abstracts

Background: Estimating the risk of complications in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) facilitates risk-benefit assessment and procedural planning.

Methods: We analyzed the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS-CTO; NCT02061436) and created a risk score for in-hospital major adverse cardiovascular events (MACE). Logistic regression prediction modeling was used to identify independently associated variables and the model was internally validated with bootstrapping.

Results: Of the 10,480 CTO PCI cases performed between 2012-2022 at 40 US and non-US centers, in-hospital MACE occurred in 215 (2.05%). The final prediction model identified 5 independent predictors of …


Tct-123 Predictors Of Success In Primary Retrograde Strategy In Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From The Progress-Cto Registry, Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Dimitri Karmpaliotis, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Sevket Gorgulu, Omer Goktekin, Oleg Krestyaninov, Rhian Davies, Ahmed Elguindy, Elias Haddad, Jimmy Kerrigan, Mitul Patel, Raj Chandwaney, Olga Mastrodemos, Salman Allana, Bavana Rangan, Emmanouil Brilakis Sep 2022

Tct-123 Predictors Of Success In Primary Retrograde Strategy In Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From The Progress-Cto Registry, Bahadir Simsek, Spyridon Kostantinis, Judit Karacsonyi, Khaldoon Alaswad, Dimitri Karmpaliotis, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Sevket Gorgulu, Omer Goktekin, Oleg Krestyaninov, Rhian Davies, Ahmed Elguindy, Elias Haddad, Jimmy Kerrigan, Mitul Patel, Raj Chandwaney, Olga Mastrodemos, Salman Allana, Bavana Rangan, Emmanouil Brilakis

Cardiology Meeting Abstracts

Background: An upfront (primary) retrograde strategy is often used in chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Methods: We examined the clinical, angiographic characteristics, and procedural outcomes of CTO PCIs that were approached with a primary retrograde strategy in the Prospective Global Registry for the Study of CTO Intervention (PROGRESS-CTO; NCT02061436). Interventional collaterals were defined as collaterals that appeared suitable for retrograde CTO PCI.

Results: Of 10,286 CTO PCIs, a primary retrograde strategy was used in 1,329 (13%) with an initial technical success of 66% and a final success of 83% with subsequent strategies. Successful vs unsuccessful primary retrograde …


Tct-117 Impact Of Proximal Cap Ambiguity On The Outcomes Of Chronic Total Occlusion Intervention: Insights From The Progress-Cto Registry, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Michael Megaly, Oleg Krestyaninov, Dmitrii Khelimskii, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Mitul Patel, Ehtisham Mahmud, Michail Koutouzis, Ioannis Tsiafoutis, Sevket Gorgulu, Basem Elbarouni, William Nicholson, Wissam Jaber, Stephane Rinfret, Omer Goktekin, Ahmed Elguindy, Yader Sandoval, M. Nicholas Burke, Salman Allana, Bavana Rangan, Emmanouil Brilakis Sep 2022

Tct-117 Impact Of Proximal Cap Ambiguity On The Outcomes Of Chronic Total Occlusion Intervention: Insights From The Progress-Cto Registry, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Michael Megaly, Oleg Krestyaninov, Dmitrii Khelimskii, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Mitul Patel, Ehtisham Mahmud, Michail Koutouzis, Ioannis Tsiafoutis, Sevket Gorgulu, Basem Elbarouni, William Nicholson, Wissam Jaber, Stephane Rinfret, Omer Goktekin, Ahmed Elguindy, Yader Sandoval, M. Nicholas Burke, Salman Allana, Bavana Rangan, Emmanouil Brilakis

Cardiology Meeting Abstracts

Background: The impact of proximal cap ambiguity on procedural techniques and outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.

Methods: We examined the clinical and angiographic characteristics and procedural outcomes of 11,169 CTO PCIs performed in 10,932 patients at 42 US and non-US centers between 2012 and 2022.

Results: Proximal cap ambiguity was present in 35% of CTO lesions. Patients whose lesions had proximal cap ambiguity were more likely to have had prior PCI (65% vs 59%; P < 0.01) and prior coronary artery bypass graft surgery (37% vs 24%; P < 0.01). Lesions with proximal cap ambiguity were more complex with higher J-CTO score (3.1 ± 1.0 vs 2.0 ± 1.2; P < 0.01) and lower technical (79% vs 90%; P < 0.01) and procedural success (77% vs 89%; P < 0.01) rates compared with non-ambiguous CTO lesions. The incidence of major adverse cardiovascular events (MACE) was higher in cases with proximal cap ambiguity (2.5% vs 1.7%; P < 0.01). The retrograde approach was more commonly used among cases with ambiguous proximal cap (51% vs 21%; P < 0.01) and was more likely to be the final successful crossing strategy (29% vs 13%; P < 0.01). PCIs of CTOs with ambiguous proximal cap required longer procedure time (140 [95-195] vs 105 [70-150] min; P < 0.01) and more contrast volume (225 [160-305] vs 200 [150-280] mL; P < 0.01).

Conclusion: Proximal cap ambiguity in CTO lesions is associated with higher utilization of the retrograde approach, …


Tct-128 Saphenous Vein Graft Occlusion Following Native Vessel Chronic Total Occlusion Percutaneous Coronary Intervention, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Michael Megaly, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Rhian Davies, Stephane Rinfret, Basem Elbarouni, Luiz Ybarra, Abdul Sheikh, Catalin Toma, Raj Chandwaney, Omer Goktekin, Ahmed Elguindy, Olga Mastrodemos, Bavana Rangan, M. Nicholas Burke, Emmanouil Brilakis Sep 2022

Tct-128 Saphenous Vein Graft Occlusion Following Native Vessel Chronic Total Occlusion Percutaneous Coronary Intervention, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Michael Megaly, Farouc Jaffer, Jaikirshan Khatri, Paul Poommipanit, Rhian Davies, Stephane Rinfret, Basem Elbarouni, Luiz Ybarra, Abdul Sheikh, Catalin Toma, Raj Chandwaney, Omer Goktekin, Ahmed Elguindy, Olga Mastrodemos, Bavana Rangan, M. Nicholas Burke, Emmanouil Brilakis

Cardiology Meeting Abstracts

Background: The practice of occluding patent saphenous vein grafts (SVGs) after successful chronic total occlusion (CTO) percutaneous coronary intervention (PCI) of the native vessel has received limited study.

Methods: We analyzed baseline clinical and angiographic characteristics and procedural outcomes of 51 patients who following successful CTO PCI of the native vessel underwent attempted SVG occlusion between 2015 and 2022 at 14 centers. Results: Mean patient age was 71 ± 8 years and 80% were men. The most common CTO target vessel was the right coronary artery (41%), followed by the left circumflex artery (35%). Retrograde crossing was the successful crossing …


Tct-170 Development And Validation Of A Scoring System For Predicting Clinical Coronary Artery Perforation During Percutaneous Coronary Interventions Of Chronic Total Occlusions: The Progress-Cto Perforation Score, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Farouc Jaffer, Jaikirshan Khatri, James Choi, Wissam Jaber, Stephane Rinfret, William Nicholson, Mitul Patel, Ehtisham Mahmud, Catalin Toma, Rhian Davies, Jimmy Kerrigan, Elias Haddad, Sevket Gorgulu, Ahmed Elguindy, Omer Goktekin, Salman Allana, M. Nicholas Burke, Olga Mastrodemos, Bavana Rangan, Emmanouil Brilakis Sep 2022

Tct-170 Development And Validation Of A Scoring System For Predicting Clinical Coronary Artery Perforation During Percutaneous Coronary Interventions Of Chronic Total Occlusions: The Progress-Cto Perforation Score, Spyridon Kostantinis, Bahadir Simsek, Judit Karacsonyi, Khaldoon Alaswad, Farouc Jaffer, Jaikirshan Khatri, James Choi, Wissam Jaber, Stephane Rinfret, William Nicholson, Mitul Patel, Ehtisham Mahmud, Catalin Toma, Rhian Davies, Jimmy Kerrigan, Elias Haddad, Sevket Gorgulu, Ahmed Elguindy, Omer Goktekin, Salman Allana, M. Nicholas Burke, Olga Mastrodemos, Bavana Rangan, Emmanouil Brilakis

Cardiology Meeting Abstracts

Background: Coronary artery perforation is a feared complication of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) and often leads to serious adverse clinical events.

Methods: We analyzed clinical and angiographic parameters from 9,618 CTO PCIs in the PROGRESS-CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention). Logistic regression prediction modeling was used to identify independently associated variables, and models were internally validated with bootstrapping. Clinical coronary artery perforation was defined as any perforation requiring treatment.

Results: The incidence of clinical coronary perforation was 3.8% (n = 367). Five factors were independently associated with perforation and were …


Invasive Versus Conservative Strategy In Elderly Patients With Non–St-Segment Elevation Myocardial Infarction: A Meta-Analysis Of Randomized Controlled Trials, Mahmoud Khalil, Muhammad H. Maqsood, Mir B. Basir, Marwan Saad, George Yassa, Laila Hakam, Bassam Hennawy, Shehad El Etriby, Santiago Garcia, Emmanouil Brilakis, Khaldoon Alaswad, Michael Megaly Sep 2022

Invasive Versus Conservative Strategy In Elderly Patients With Non–St-Segment Elevation Myocardial Infarction: A Meta-Analysis Of Randomized Controlled Trials, Mahmoud Khalil, Muhammad H. Maqsood, Mir B. Basir, Marwan Saad, George Yassa, Laila Hakam, Bassam Hennawy, Shehad El Etriby, Santiago Garcia, Emmanouil Brilakis, Khaldoon Alaswad, Michael Megaly

Cardiology Meeting Abstracts

Background: Management of non–ST-segment elevation myocardial infarction (NSTEMI) has evolved over the years, but most published data are from younger patients. Data on the NSTEMI management in elderly patients remains limited. Methods: We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the long-term outcomes of invasive vs conservative strategies in elderly patients with NSTEMI.

Results: Of 1,550 reports searched, 4 RCTs (1,126 patients) were included in the analysis with a median follow-up of 1.25 years (range: 1 to 2.5 years). The median age of included patients was 83.6 (IQR 2.8 years). The invasive strategy was associated with significantly …


Tct-109 Use Of Subintimal Tracking And Reentry Technique In Chronic Total Occlusion Percutaneous Coronary Intervention, Judit Karacsonyi, Spyridon Kostantinis, Bahadir Simsek, Khaldoon Alaswad, Dimitri Karmpaliotis, Ajay Kirtane, Margaret Mcentegart, Farouc Jaffer, James Choi, Paul Poommipanit, Michalis Koutouzis, Ioannis Tsiafoutis, Jaikirshan Khatri, David Kandzari, Ray Chandwaney, Basem Elbarouni, Sevket Gorgulu, Ahmed Elguindy, Nidal Abi-Rafeh, Omer Goktekin, Imre Ungi, Bavana Rangan, Olga Mastrodemos, Yader Sandoval, Salman Allana, M. Nicholas Burke, Emmanouil Brilakis Sep 2022

Tct-109 Use Of Subintimal Tracking And Reentry Technique In Chronic Total Occlusion Percutaneous Coronary Intervention, Judit Karacsonyi, Spyridon Kostantinis, Bahadir Simsek, Khaldoon Alaswad, Dimitri Karmpaliotis, Ajay Kirtane, Margaret Mcentegart, Farouc Jaffer, James Choi, Paul Poommipanit, Michalis Koutouzis, Ioannis Tsiafoutis, Jaikirshan Khatri, David Kandzari, Ray Chandwaney, Basem Elbarouni, Sevket Gorgulu, Ahmed Elguindy, Nidal Abi-Rafeh, Omer Goktekin, Imre Ungi, Bavana Rangan, Olga Mastrodemos, Yader Sandoval, Salman Allana, M. Nicholas Burke, Emmanouil Brilakis

Cardiology Meeting Abstracts

Background: There are limited data on the use of the subintimal tracking and reentry (STAR) technique for chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Methods: We analyzed 2,353 CTO PCIs performed using antegrade dissection re-entry (ADR) in the PROGRESS-CTO Registry, between 2012 and June 2022 at 41 centers.

Results: STAR was used in 450 cases (19.1%), primary STAR in 325 (13.8%) and secondary STAR (STAR after other ADR approaches) in 125 (5.3%). The Stingray system was used in 1,048 (44.5%), limited antegrade subintimal tracking (LAST) in 177 (7.5%), and contrast-guided STAR in 31 (1.3%) of re-entry cases. The mean …


Prosecutorial Nonenforcement And Residual Criminalization, Justin Murray Sep 2022

Prosecutorial Nonenforcement And Residual Criminalization, Justin Murray

Articles & Chapters

In recent years a small but influential group of locally elected prosecutors committed to criminal justice reform have openly refused to enforce various criminal laws—laws prohibiting marijuana possession, sentence enhancements, laws authorizing the death penalty, and much more—because they see those laws as unjust and incompatible with core reform objectives. Condemned by many on the political right for allegedly usurping the legislature’s lawmaking role and praised by many on the left for bypassing dysfunctional state legislatures in favor of local solutions, these prosecutorial nonenforcement policies are commonly said to have the same effect as nullifying, or even repealing, the laws …


Reconstructing The Ethics Code To Remedy The Failures Of Strickland V. Washington, Heather Ellis Cucolo Sep 2022

Reconstructing The Ethics Code To Remedy The Failures Of Strickland V. Washington, Heather Ellis Cucolo

Articles & Chapters

No abstract provided.


But I Ain’T A Judge: The Therapeutic Jurisprudence Implications Of The Use Of Nonjudicial Officers In Criminal Justice Cases, Michael L. Perlin Sep 2022

But I Ain’T A Judge: The Therapeutic Jurisprudence Implications Of The Use Of Nonjudicial Officers In Criminal Justice Cases, Michael L. Perlin

Articles & Chapters

The role of nonjudicial officers occupies a hidden space in the U.S. judicial system. Statutorily sanctioned in many jurisdictions, such officers have a wide range of duties and responsibilities, including hearing certain pretrial motions in criminal cases and making decisions as to conditions of probation for sex offenders. These latter officers are frequently not lawyers, and there is significant evidence that many of the basic rudiments of the criminal trial process are often not honored. There has been virtually no consideration of this phenomenon in the scholarly literature, and absolutely no consideration from the perspective of therapeutic jurisprudence (TJ). An …


Impaired Calcium Signalling And Neuropsychiatric Disorders In Darier Disease: An Exploratory Review, Austin Ambur, Asma Zaidi, Charles Dunn, Rajiv Nathoo Sep 2022

Impaired Calcium Signalling And Neuropsychiatric Disorders In Darier Disease: An Exploratory Review, Austin Ambur, Asma Zaidi, Charles Dunn, Rajiv Nathoo

Faculty and Staff Publications

Darier (Darier-White) disease (DD) is an autosomal dominant skin disorder caused by pathogenic mutations in the ATP2 A 2 gene which encodes a calcium ATPase in the sarco-endoplasmic reticulum (SERCA2). Defects in the SERCA2 protein lead to an impairment of cellular calcium homeostasis, which in turn, triggers cell death path-ways. There is a high prevalence of neuropsychiatric disorders in patients affected by this condition, namely intellectual disability, bipolar disorder, schizophrenia, and suicidality. Though these associations have been well-documented over the years, little has been discussed or investigated regarding the pathophysiological mecha-nisms. The goal of this article is to review the …


Ep 45 Description: Salaries And Overtime, Wages Vs Salary, Eva Moss, Kate Cowie-Haskell Sep 2022

Ep 45 Description: Salaries And Overtime, Wages Vs Salary, Eva Moss, Kate Cowie-Haskell

UNH Cooperative Extension

No abstract provided.


Secured Transactions Law In Asia: Principles, Perspectives And Reform By Louise Gullifer And Dora Neo, Wee Ling Loo Sep 2022

Secured Transactions Law In Asia: Principles, Perspectives And Reform By Louise Gullifer And Dora Neo, Wee Ling Loo

Research Collection Yong Pung How School Of Law

Secured Transactions Law in Asia: Principles, Perspectives and Reform is the third in a series of works that critically examine secured transactions law reform around the world. From a focus on reforms in Europe in the first book to reforms in Africa in the second, this third volume looks at Asia, and specifically at reforms in 13 major Asian jurisdictions: China, Indonesia, Japan, Philippines, South Korea, Taiwan, Thailand, Vietnam, Brunei Darussalam, Bangladesh, India, Pakistan and Singapore. The collection of essays by leading experts from academia, legal practice and the World Bank Group was first presented at a 2018 conference jointly …


Study On Apparent Permeability Model For Gas Transport In Shale Inorganic Nanopores, Shuda Zhao, Hongji Liu, Enyuan Jiang, Nan Zhao, Chaohua Guo, Baojun Bai Sep 2022

Study On Apparent Permeability Model For Gas Transport In Shale Inorganic Nanopores, Shuda Zhao, Hongji Liu, Enyuan Jiang, Nan Zhao, Chaohua Guo, Baojun Bai

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Inorganic nanopores occurring in the shale matrix have strong hydrophilicity and irreducible water (IW) film can be formed on the inner surface of the pores making gas flow mechanisms in the pores more complex. In this paper, the existence of irreducible water (IW) in inorganic pores is considered, and, based on the Knudsen number (K (Formula presented.)) correction in shale pores, a shale gas apparent permeability model of inorganic nano-pores is established. The effect of the K (Formula presented.) correction on the apparent permeability, the ratio of flow with pore radius and the effect of IW on the apparent permeability …


Fabrications And Applications Of Micro/Nanofluidics In Oil And Gas Recovery: A Comprehensive Review, Junchen Liu, Yandong Zhang, Mingzhen Wei, Xiaoming He, Baojun Bai Sep 2022

Fabrications And Applications Of Micro/Nanofluidics In Oil And Gas Recovery: A Comprehensive Review, Junchen Liu, Yandong Zhang, Mingzhen Wei, Xiaoming He, Baojun Bai

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Understanding fluid flow characteristics in porous medium, which determines the development of oil and gas oilfields, has been a significant research subject for decades. Although using core samples is still essential, micro/nanofluidics have been attracting increasing attention in oil recovery fields since it offers direct visualization and quantification of fluid flow at the pore level. This work provides the latest techniques and development history of micro/nanofluidics in oil and gas recovery by summarizing and discussing the fabrication methods, materials and corresponding applications. Compared with other reviews of micro/nanofluidics, this comprehensive review is in the perspective of solving specific issues in …


Nurses’ Knowledge And Practice In Managing Covid-19 Patients With Cardiac Arrest At A Teaching Hospital, Li Yoong Tang Sep 2022

Nurses’ Knowledge And Practice In Managing Covid-19 Patients With Cardiac Arrest At A Teaching Hospital, Li Yoong Tang

Research Publications (2021 to 2025)

The COVID-19 pandemic has posed a major threat to public health. The same goes for the healthcare providers, as they too are at great risk of being infected with the virus. COVID-19 disease may cause the patient's hemodynamically instability thus causing circulatory system collapse. Therefore, the nurses who are part of the resuscitation team should adapt themselves with knowledge and good practice on how to handle the COVID-19 patients with cardiac arrest. This study aimed to assess the nurses' knowledge and practice in managing COVID-19 patients with cardiac arrest at a teaching hospital.


Advanced Glycation End Products In Health And Disease, V. Prakash Reddy, Puspa Aryal, Emmanuel K. Darkwah Sep 2022

Advanced Glycation End Products In Health And Disease, V. Prakash Reddy, Puspa Aryal, Emmanuel K. Darkwah

Chemistry Faculty Research & Creative Works

Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are involved in the onset and exacerbation of a variety of diseases, including diabetes, atherosclerosis, and Alzheimer's disease (AD) as well as in the secondary stages of traumatic brain injury (TBI). AGEs, in the form of intra- and interprotein crosslinks, deactivate various enzymes, exacerbating disease progression. The interactions of AGEs with the receptors for the AGEs (RAGE) also result in further downstream inflammatory cascade events. The overexpression …


Polyphenols And Small Phenolic Acids As Cellular Metabolic Regulators, Mark Obrenovich, Yi Li, Moncef Tayahi, V. Prakash Reddy Sep 2022

Polyphenols And Small Phenolic Acids As Cellular Metabolic Regulators, Mark Obrenovich, Yi Li, Moncef Tayahi, V. Prakash Reddy

Chemistry Faculty Research & Creative Works

Polyphenols and representative small phenolic acids and molecules derived from larger constituents are dietary antioxidants from fruits, vegetables and largely other plant-based sources that have ability to scavenge free radicals. What is often neglected in polyphenol metabolism is bioavailability and the role of the gut microbiota (GMB), which has an essential role in health and disease and participates in co-metabolism with the host. The composition of the gut microbiota is in constant flux and is modified by multiple intrinsic and extrinsic factors, including antibiotics. Dietary or other factors are key modulators of the host gut milieu. In this review, we …


Crystal Structure, Electronic Structure, And Optical Properties Of The Novel Li4cdge2s7, A Wide-Bandgap Quaternary Sulfide With A Polar Structure Derived From Lonsdaleite, Andrew J. Craig, Seung Han Shin, Jeong Bin Cho, Srikanth Balijapelly, Jordan C. Kelly, Stanislav S. Stoyko, Amitava Choudhury, Joon I. Jang, Jennifer A. Aitken, A. Sarjeant Sep 2022

Crystal Structure, Electronic Structure, And Optical Properties Of The Novel Li4cdge2s7, A Wide-Bandgap Quaternary Sulfide With A Polar Structure Derived From Lonsdaleite, Andrew J. Craig, Seung Han Shin, Jeong Bin Cho, Srikanth Balijapelly, Jordan C. Kelly, Stanislav S. Stoyko, Amitava Choudhury, Joon I. Jang, Jennifer A. Aitken, A. Sarjeant

Chemistry Faculty Research & Creative Works

The novel quaternary thiogermanate Li4CdGe2S7 (tetralithium cadmium digermanium heptasulfide) was discovered from a solid-state reaction at 750 °C. Single-crystal X-ray diffraction data were collected and used to solve and refine the structure. Li4CdGe2S7 is a member of the small, but growing, class of I4-II-IV2-VI7 diamond-like materials. The compound adopts the Cu5Si2S7 structure type, which is a derivative of lonsdaleite. Crystallizing in the polar space group Cc, Li4CdGe2S7 contains 14 crystallographically unique ions, all residing on …


Inconceivable Families, Malinda L. Seymore Sep 2022

Inconceivable Families, Malinda L. Seymore

Faculty Scholarship

Basic biology tells us that each child has no more than two biological parents, one who supplies the egg and one who supplies the sperm. Adoption law in this country has generally followed biology, insisting only two parents be legally recognized for each child. Thus, every adoption begins with loss. Before a child can be adopted, that child must first be cut off from their family of birth, rendering the equation of adoption one of subtraction, not addition. This Article examines the biological model of adoption that insists on mimicking the nuclear family—erasing one set of parents and replacing them …