Digital Commons Network^™

33354 Efficacy Of Apremilast In Patients With Mild To Moderate Psoriasis Assessed By The Physician Global Assessment And Body Surface Area Composite Tool: Post Hoc Analysis From Advance, Linda F. Stein Gold, Kim Papp, David Pariser, Howard Sofen, Mindy Chen, Sue Cheng, Hernan Picard, Yuri Klyachkin, Lawrence Green

Dermatology Meeting Abstracts

Background: In ADVANCE (NCT03721172), apremilast 30 mg BID (APR) demonstrated significantly greater sPGA response vs. PBO at Week 16 (22% vs. 4%; P <.0001) in patients with mild-to-moderate psoriasis. The Physician Global Assessment and Body Surface Area Composite Tool (PGA × BSA) is a simple, sensitive measure of psoriasis severity for patients with BSA<10%. We performed a post hoc analysis of the efficacy results from ADVANCE using the PGA×BSA.

Methods: This current post hoc analysis included all randomized patients. Missing data were imputed by multiple imputation. PGAxBSA-50/75/90 was 50%, 75% and 90% improvement in PGAxBSA from baseline.

Results: Of 595 randomized patients (APR: 297; PBO: 298), baseline characteristics were similar for mean BSA (APR: 6.4; PBO: 6.3), sPGA score 2 (APR 31%; PBO: 31%), sPGA score 3 (APR: 69%; PBO: 70%), and mean PGA×BSA (APR: 17.6; PBO: 17.5). At Week 16, significantly more patients achieved PGAxBSA-50/75/90 …

35360 Recalcitrant Pediatric Bullous Erythema Multiforme Responsive To Oral Tofacitinib, Sasank Konda, Nayha Shetty, Jesse Y. Liu

Dermatology Meeting Abstracts

Patient history and physical: A 25-year-old African American female was admitted for painful oral erosions and widespread blistering lesions on the trunk and extremities which had been waxing and waning since age 12 years old. Disease flares requiring hospitalization had been continuing to occur multiple times annually in spite of numerous systemic immunosuppressive agents including chronic corticosteroids (resulting in Cushingoid features and insulin-dependent diabetes) in combination with cyclosporine, dapsone, tacrolimus, anakinra, rituximab, adalimumab, apremilast, mycophenolate mofetil, and intravenous immunoglobulin (IVIG) at various times. Adjunctive therapies including acyclovir and leuprolide had also proven ineffective. Physical examination revealed well-defined, targetoid macules with …

34441 Keratoderma Blenorrhagicum And Balanitis Circinata: Indicators Of Reactive Arthritis, Dayoung Ko, Meredith Hengy, Chauncey A. Mchargue

Dermatology Meeting Abstracts

A 25-year-old healthy man was admitted with a 3-month history of joint pains in his feet and right knee, leading to difficulty ambulating. The patient had been previously treated without a definitive diagnosis, with NSAIDs and systemic steroids, without improvement. He also endorsed a 3-week history of an extensive, diffuse rash with significant involvement of the palms, soles, and genitals. He denied involvement in the oral mucosa or conjunctiva. Lesions were tender—the plantar lesions contributing significantly to painful ambulation. The physical examination was notable for hyperkeratotic scaly purpuric papules and plaques on the soles and between the toes, hyperkeratotic ostraceous …

35224 Identifying A Correlation Between Preceding Trauma And Development Of Dermatofibrosarcoma Protuberans: A Review Of The Literature, Brittani Jones, Jesse Veenstra, David M. Ozog

Dermatology Meeting Abstracts

Background: Dermatofibrosarcoma protuberans (DFSP) is a malignant fibrohistiocytic neoplasm that is slow-growing, has low metastatic potential, and is locally infiltrative with a predisposition for recurrence. The development of DFSP can occur spontaneously, but anecdotal evidence suggests a correlation between preceding injury and tumor onset.

Methods: A comprehensive literature search was performed using PubMed, Embase, and web of science for articles with unambiguous reporting of DFSP with a history of physical trauma. Of 139 identified articles, 23 (17%) met criteria and were analyzed.

Results: In total, 52 patients were reported as having had some form of physical trauma prior to DFSP …

35186 Exploring The Association Between Frontal Fibrosing Alopecia Sunscreen And Moisturizers, Jalal Maghfour, Joshua Olson

Dermatology Meeting Abstracts

Frontal fibrosing alopecia (FFA) is an immune-mediated cicatricial alopecia. Skin care products including sunscreen were suggested to influence disease pathogenesis. Given the conflicting data, the aim of this study is to provide a quantitative summary on this topic. A systematic search surveying PubMed database was conducted in August 2021. The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed. The study was prospectively registered in Prospero (ID: 273840). The pooled effect size is presented as odds ratio (OR) with 95% confidence interval (CI). A total of 87 articles were identified; 9 articles were included. Using the Newcastle Ottawa …

33778 The Impact And Implications Of Covid-19 On Using Scalp Cooling Therapy For Prevention Of Chemotherapy-Induced Alopecia, Taylor Novice, Madison Novice, Katerina Svigos, Molly Powers, Kristen Lo Sicco

Dermatology Meeting Abstracts

Background: Scalp cooling therapy (SCT) is currently the most effective method to reduce chemotherapy-induced alopecia. Manual SCT requires a “capper” to change the caps throughout the infusion day whereas machine SCT only requires a 1-time cap fitting prior to infusion, usually performed by the health care staff. Coronavirus disease 2019 (COVID-19) brought restrictions on permitted infusion center visitors, which we hypothesized would include “cappers,” creating an additional barrier to SCT use.

Methods: A scripted call was placed during May 2021 by a study author to infusion centers of Commission on Cancer (CoC) accredited hospitals in Michigan, New York City (NYC) …

34745 Us And Eu Sunscreens: A Review Of Ultraviolet (Uv) Filters And Safety Data, Nikita Wong, Milan N. Pantelic, Michael Kwa

Dermatology Meeting Abstracts

A broad range of UV filters are available for use in sunscreen products. Knowledge of UV filters available both domestically and abroad remains important, since these products can be found in the online marketplace and may be included in future FDA monographs as a shift is made to an administrative order process. We reviewed the mechanism and safety data of all US and EU approved UV filters. Currently, there are 17 US FDA approved UV filters while the EU possesses an additional 16 UV filters. Of the US filters, 88.2% (15/17) are organic and 11.8% (2/17) are inorganic filters, with …

35180 “Could I Be Allergic To My New Hidradenitis Suppurativa Medication?” Characterization Of A Cutaneous Delayed-Type Drug Hypersensitivity Reaction To Secukinumab, Nayha Shetty, Sasank Konda, Jesse Veenstra

Dermatology Meeting Abstracts

Patient history and physical: A 32-year-old Asian-American female presented with widespread, pruritic, red papules involving the ears, trunk, and extremities for approximately 6 weeks’ duration. The lesions first developed several days after her second secukinumab injection, which was originally initiated for recalcitrant stage III hidradenitis suppurativa. Physical examination revealed numerous erythematous, scaly papules on the bilateral ears, upper chest, inframammary folds, bilateral upper extremities, and abdomen (including umbilicus). Large, well-demarcated, moist-appearing plaques were observed to involve the bilateral axillary folds symmetrically. Her vital signs were stable, and she denied recent facial swelling or urticaria.

Pathology: A punch biopsy obtained from …

Towards An Operational Irrigation Management System For Sweden With A Water–Food–Energy Nexus Perspective, P. E. Campana, P. Lastanao, S. Zainali, J. Zhang, T. Landelius, F. Melton

AES Faculty Publications and Presentations

The 2018 drought in Sweden prompted questions about climate-adaptation and -mitigation measures – especially in the agricultural sector, which suffered the most. This study applies a water–food–energy nexus modelling framework to evaluate drought impacts on irrigation and agriculture in Sweden using 2018 and 2019 as case studies. A previous water–food–energy nexus model was updated to facilitate an investigation of the benefits of data-driven irrigation scheduling as compared to existing irrigation guidelines. Moreover, the benefits of assimilating earth observation data in the crop model have been explored. The assimilation of leaf area index data from the Copernicus Global Land Service improves …

Musi 395.10: Applied Study Iii - Voice, Katie E. Martin

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Musi 395.04: Applied Study Iii - Trombone, Robert D. Tapper

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Evidence For An Interaction Between The Galactic Center Clouds M0.10-0.08 And M0.11-0.11, Natalie O. Butterfield, Cornelia C. Lang, Adam Ginsburg, Mark R. Morris, Jürgen Ott, Dominic A. Ludovici

Physics and Engineering Science

We present high-resolution (∼2-3″; ∼0.1 pc) radio observations of the Galactic center cloud M0.10−0.08 using the Very Large Array at K and Ka band (∼25 and 36 GHz). The M0.10−0.08 cloud is located in a complex environment near the Galactic center Radio Arc and the adjacent M0.11−0.11 molecular cloud. From our data, M0.10−0.08 appears to be a compact molecular cloud (∼3 pc) that contains multiple compact molecular cores (5+; <0.4 pc). In this study, we detect a total of 15 molecular transitions in M0.10−0.08 from the following molecules: NH3, HC3N, CH3OH, HC5N, CH3CN, and OCS. We have identified more than sixty 36 GHz CH3OH masers in M0.10−0.08 with brightness temperatures above 400 K and 31 maser candidates with temperatures between 100 and 400 K. We conduct a kinematic analysis of the gas using NH3 and detect multiple velocity components toward this region of the Galactic center. The bulk of the gas in this region has a velocity of 51.5 km s⁻¹ (M0.10−0.08) with a lower-velocity wing at 37.6 km s⁻¹. We also detect a relatively faint velocity component at 10.6 km s⁻¹ that we attribute to being an …

Figuring Embedded Librarianship: An Analysis Of The Embedded Journalist Metaphor In The Professional Discourse, Rachel L. Edford

Faculty Scholarship and Creative Works

In the wake of the COVID pandemic, many academic libraries sought virtual instruction options, like the embedded librarian model, bringing renewed interest to the topic. Debates defining embedded librarianship are plentiful and varied, but a review of the professional literature reveals a commonly used metaphor comparing embedded librarians to embedded journalists. This paper analyses the prevalence of that metaphor in the professional discourse through the lens of cognitive metaphor theory (CMT) to reveal the semantic and pragmatic implications of its use. CMT highlights the power of figurative language to reflect and define professional identities. The metaphor’s militaristic rhetoric counters negative …

Vol. 51, No. 1: Table Of Contents, Denver Journal Of International Law & Policy

Denver Journal of International Law & Policy

No abstract provided.

International Law, African Courts, Patriarchal Inheritance Systems And Women's Rights, John Mukum Mbaku

Denver Journal of International Law & Policy

In virtually all countries in Africa, there exist various cultural, social, political, and legal factors that contribute to women's inability to have access to land, as well as negatively impact their inheritance rights. One of the most important reasons why so many women in Africa do not have access to land or official land titles is that they live in communities which have customary laws and traditional practices that deny them the right to inheritance. In several African countries, customary laws deny the girl child the right to inherit her deceased father's estate and the widow the right to inherit …

Vol. 51, No. 1: Full Issue, Denver Journal Of International Law & Policy

Denver Journal of International Law & Policy

No abstract provided.

Vol. 51, No. 1: Faculty And Admin, Denver Journal Of International Law & Policy

Denver Journal of International Law & Policy

No abstract provided.

The Bridwell Quill. Issues 47-49: Of Antiquities And Mindfulness, Anthony Elia

Bridwell Library Publications

No abstract provided.

Barriers To Anti-Retroviral Therapy Adherence Among Adolescents Aged 10 To 19 Years Living With Hiv In Sub-Saharan Africa: A Mixed-Methods Systematic Review Protocol, Londiwe D. Hlophe, Jacques L. Tamuzi, Constance Shumba, Peter S. Nyasulu

School of Nursing & Midwifery, East Africa

Background: Antiretroviral therapy (ART) adherence is fundamental in achieving viral load suppression and consequently attaining positive health outcomes among people living with HIV. However, ART adherence is sub-optimum among adolescents living with HIV (ALHIV) thus the high AIDS-related mortality even after World Health Organization (WHO) revised HIV treatment eligibility guidelines in 2010, 2013 and 2016. Consolidated trends of barriers to ART adherence among ALHIV aged 10 to 19 years in sub-Saharan countries post each eligibility guidelines revision to date are unknown.

Methods and analysis: We will conduct comprehensive search of peer-reviewed and grey literature databases publishing observational studies reporting data …

Shore-Based Recreational Fishing In The Perth Metropolitan Area: 2022, Alissa Tate, Lucy Rudd, Claire B. Smallwood

Fisheries Research Reports

Recreational fishing is a popular activity in Western Australia (WA), occurring throughout the state from boats, and from a variety of natural and man-made structures along the shore. Ongoing monitoring of the shore-based recreational fishery is essential to assist with resource allocation, management evaluation and stock assessments for nearshore species. Especially for species such as Australian Herring and Southern Garfish which had management changes including a reduction in bag limit from 30 to 12 in 2015 and closure of Perth Metropolitan waters in 2017, respectively. An on-site roving creel survey to collect effort and catch data from shore fishers has …

Music Reviews, Volume 79, No. 1, Kathleen Roland-Silverstein

Voice - All Scholarship

Contains reviews of The Paper Lined Shack; Canciones de la Tierra; Czech Arias for Soprano: An Anthology

Comments From The Editor, Robert M. Mangione, Susan V. Iverson

New York Journal of Student Affairs

Editor comments for Volume 22.

A Hybrid Subcutaneous And Epicardial Biventricular Implantable Cardiac Defibrillator With An Abdominal Generator, Mohamed Raad, Kyle Miletic, Arfaat Khan, Waddah Maskoun

Cardiology Articles

No abstract provided.

Need Not Hire Here: Where Colorado's "Equal Pay For Equal Work" Act Could Better Serve Its Residents

Hofstra Labor & Employment Law Journal

No abstract provided.

The Role Of Agents And Brokers In Facilitating Ethiopian Women Into Domestic Work In The Middle East: Findings From The Meneshachin (‘Our Departure’) Study On Responsible Recruitment Models, Joanna Busza, Zewdneh Sabe, Cathy Zimmerman

Gender Equality and Equity

Large numbers of Ethiopian women seek domestic work in the Middle East Corridor—a significant social trend that reflects a key livelihood strategy used by Ethiopian families and communities in the face of widespread poverty. Research related to this type of migration is extensive, but mainly concentrated on the “push” and “pull” factors and the potential risks of labor exploitation, trafficking, and resultant threats to migrants’ physical, mental, and sexual health. The research presented here represents one of the few studies examining how women plan their migration experiences, whom they rely on for emotional, economic, or practical assistance, and what roles …

655mo Quality Of Life In Patients With P16+ Oropharyngeal Cancer Receiving Accelerated Radiotherapy (Rt) With Either Cisplatin Or Cetuximab In Nrg/Rtog 1016, J. Ringash, L. Demora, M. L. Gillison, D. J. Adelstein, P. Harari, E. M. Sturgis, E. M. Basch, S. A. Koyfman, G. A. Krempl, D. M. Blakaj, J. E. Bates, T. Galloway, C. U. Jones, B. M. Beadle, P Torres-Saavedra, Q. T. Le, Benjamin Movsas

Radiation Oncology Meeting Abstracts

Background: This phase 3 randomized non-inferiority de-escalation trial compared cetuximab (cetux) vs cisplatin (cis), concurrent with accelerated RT 70 Gy/6 weeks, in p16+ oropharyngeal cancer (OPC). Quality of life (QOL) was an important secondary endpoint.

Methods: EORTC QLQ-C30/HN35 was completed at baseline, end of treatment, 3, 6, and 12 months post. The substudy aimed for 400 eligible patients. We report completion rates and compare by arm for change from baseline in each domain (0.05 two-sided alpha and MID of 10 points) using linear mixed models.

Results: Consent was 91% (381/419 offered substudy); 6 protocol deviations excluded (n=375). No significant differences …

Reduced Social Contact And Attachment Insecurity As Predictors Of Loneliness During Covid-19: A Two-Month Experience Sampling Study, Katie C. Lewis, Michael J. Roche, Fiona Brown, Jane G. Tillman

Psychology Faculty Publications

The impact of reduced social contact on mental health during the COVID-19 pandemic has been identified as a major public health concern. While personality factors such as attachment style have been associated with psychological distress during the pandemic, the longitudinal relevance of these factors and the role of daily social contact in mitigating distress remains poorly understood. This study evaluated the impact of social contact and attachment style on changes in loneliness over an 8-week experience sampling period during the COVID-19 pandemic. A general adult sample (n = 184) recruited online completed measures of psychological distress, attachment, and loneliness via …

Use Of Twitter Among College Students For Academics: A Mixed-Methods Approach, Stefanie Amiruzzaman, Md Amiruzzaman

Languages & Cultures Faculty Publications

For almost a decade, Twitter use and its impact on students' academic performance have been explored by many researchers. Despite growing scholarly interest, studies have been mostly quantitative in nature. The findings of previous studies are conflicting; thus, an in-depth study is needed to determine how and what impacts college students' academic performance (i.e., GPA) when they spend time on Twitter. The purpose of this study was to understand the effects of Twitter use on college students' academic performance. The present study shows that individual analysis techniques, such as quantitative or qualitative tools, are not enough to understand the underlying …

Community-Powered Urban Stream Restoration: A Vision For Sustainable And Resilient Urban Ecosystems, Mateo Scoggins, Derek B. Booth, Tim Fletcher, Megan Fork, Ana Gonzalez, Rebecca L. Hale, Robert J. Hawley, Allison H. Roy, Erika E. Bilger, Nick Bond, Matthew James Burns, Kristina G. Hopkins, Kate H. Macneale, Eugenia Marti, Kyle S. Mckay, Martin W. Neale, Michael J. Paul, Blanca Rios-Touma, Kathryn L. Russell, Robert F. Smith, Staryn Wagner, Seth Wenger

Biology Faculty Publications

Urban streams can provide amenities to people living in cities, but those benefits are reduced when streams become degraded, potentially even causing harm (disease, toxic compounds, etc.). Governments and institutions invest resources to improve the values and services provided by urban streams; however, the conception, development, and implementation of such projects may not include meaningful involvement of community members and other stakeholders. Consequently, project objectives may be misaligned with community desires and needs, and projects may fail to achieve their goals. In February 2020, the 5(th) Symposium on Urbanization and Stream Ecology, an interdisciplinary meeting held every 3 to 5 …

League Of Women Voters Of The Huntington Area E-Mail Bulletin, September 2022, League Of Women Voters Of The Huntington Area

League of Women Voters of the Huntington Area Bulletin 2020 - Present

The Bulletin is published by the League, which is a nonpartisan political organization that encourages the informed and active participation of citizens in government and influences public policy through education and advocacy.