Digital Commons Network^™

Yap And Taz Promote Osteogenesis And Prevent Chondrogenesis In Neural Crest Cells In Vitro And In Vivo, Xiaolei Zhao, Li Tang, Tram P Le, Bao H Nguyen, Wen Chen, Mingjie Zheng, Hiroyuki Yamaguchi, Brian Dawson, Shuangjie You, Idaliz M Martinez-Traverso, Shannon Erhardt, Jianxin Wang, Min Li, James F Martin, Brendan H Lee, Yoshihiro Komatsu, Jun Wang

Faculty, Staff and Student Publications

Neural crest cells (NCCs) are multipotent stem cells that can differentiate into multiple cell types, including the osteoblasts and chondrocytes, and constitute the majority of the craniofacial skeleton. Here, we show through in vitro and in vivo studies that the transcriptional regulators Yap and Taz have redundant functions as key determinants of the specification and differentiation of NCCs into osteoblasts or chondrocytes. Primary and cultured NCCs deficient in Yap and Taz switched from osteogenesis to chondrogenesis, and NCC-specific deficiency for Yap and Taz resulted in bone loss and ectopic cartilage in mice. Yap bound to the regulatory elements of key …

"A Sort Of Pain, Which Is New": Unresolved Grief In British Romantic Literature, Eta Farmacelia Nurulhady

LSU Doctoral Dissertations

This dissertation examines the cultural phenomenon of mourning in relation to British Romantic Literature. In chapters on the work of William Wordsworth, Jane Austen, Felicia Hemans, and Charles Lamb, it argues that the Romantic period, as a time of increased mobility due to three revolutions, wars, and the expansion of empire, was a moment when unresolved grief became a common experience. Using the psychologist Pauline Boss’s concept of “ambiguous loss” as a lens for a new reading of British Romantic writing, and distinguishing this concept from the modern concept of “nostalgia,” this dissertation analyzes poetry, novels, and essays written by …

Synthesis Of Carbon Nanohoops And Macrocycles Via Alkyne Metathesis, Xin Zhou

LSU Doctoral Dissertations

Cycloparaphenyleneacetylene (CPPA) and cycloparaphenylene (CPP) are called carbon nanohoops; they are fully conjugated macrocycles with radially oriented aromatic groups. Though many syntheses of CPPA and CPP were reported, in the macrocyclization step, the yields were usually not satisfying, as the reactions were irreversible. Our group utilizes alkyne metathesis to address this problem. Chapter 1 provides backgrounds and an introduction to the carbon nanohoops and alkyne metathesis.

Chapter 2 details the synthesis of the [3]CPP⁴A and [3]CPP⁵A, with good macrocyclization yields via alkyne metathesis. This study showed the error-correction ability of alkyne metathesis, especially with nonsymmetric substrates. …

Auditing Standards Board (Asb) Meeting Highlights, October 25-26, 2022 Videoconference, American Institutde Of Certified Public Accountants. Auditing Standards Board

Association Sections, Divisions, Boards, Teams

No abstract provided.

Auditing Standards Board (Asb), Meeting Highlights, October 25-26, 2022, Videoconference, American Institute Of Certified Public Accountants. Auditing Standards Board

Association Sections, Divisions, Boards, Teams

No abstract provided.

Auditing Standards Board (Asb), Meeting Agenda, October 25-26, 2022 Virtual (Times Are Est) Updated Agenda (As Of October 4, 2022), American Institute Of Certified Public Accountants. Auditing Standards Board

Association Sections, Divisions, Boards, Teams

No abstract provided.

Human Neutrophil Development And Functionality Are Enabled In A Humanized Mouse Model, Yunjiang Zheng, Esen Sefik, John Astle, Kutay Karatepe, Hasan H Öz, Angel G Solis, Ruaidhrí Jackson, Hongbo R Luo, Emanuela M Bruscia, Stephanie Halene, Liang Shan, Richard A Flavell

2020-Current year OA Pubs

Mice with a functional human immune system serve as an invaluable tool to study the development and function of the human immune system in vivo. A major technological limitation of all current humanized mouse models is the lack of mature and functional human neutrophils in circulation and tissues. To overcome this, we generated a humanized mouse model named MISTRGGR, in which the mouse granulocyte colony-stimulating factor (G-CSF) was replaced with human G-CSF and the mouse G-CSF receptor gene was deleted in existing MISTRG mice. By targeting the G-CSF cytokine-receptor axis, we dramatically improved the reconstitution of mature circulating and tissue-infiltrating …

Discovery Of A Novel Genomic Alteration That Renders Leukemic Cells Resistant To Cd19-Targeted Immunotherapies, Armin Ghobadi, Jack H Landmann, Alun Carter, Matthew L Cooper, Mehmet Emrah Selli, Jufang Chang, Christopher A Miller, Francesca Ferraro, David Y Chen, Amanda M Smith, Taylor A Lavalle, Eric J Duncavage, Nathan Singh, Et Al.

2020-Current year OA Pubs

No abstract provided.

Factors Driving The Tourists Choice Of Alcohol And Drinkscapes: An Exploratory Study, Edgar Philip Dsouza Mr., Dayanand M.S. Dr., Nilesh Borde Dr

Journal of Tourism Insights

This study analyses the crucial dimension of variables influencing visitors' choice of drinkscapes and alcohol among those who visited Goa. This research also aims to examine the influence of tourists' knowledge and past experiences regarding alcohol consumption on the choice of alcoholic beverages and the choice of drinkscapes at tourist destinations. Respondents were asked to rate provided attributes on a 5-point Likert scale according to their preferences in selecting alcohol or drinkscapes. Four hundred and eighty-one questionnaires collected from a web-based survey at popular drinkscapes in Goa were analyzed. The research ranks attribute based on the mean values used by …

Role Of Young Adults In Family Vacation Decision Making: A Study Across Gender, Shayan Basharat Fazili, Anisa Jan

Journal of Tourism Insights

In recent years, family vacation decision-making has grown in importance as a subject of research for tourism academics since it helps practitioners develop specialized marketing strategies for their target market. However, there hasn't been much focus on how different family members perform during the many stages of deciding on a family vacation. This study examines the three primary stages of choosing a family vacation and the part that young adults play in each stage of this process. The purpose of this study is to understand how young adults engage in choosing family trips. Additionally, this study attempts to examine how …

Personal Factors Influencing Us Travelers’ Sentiments Toward Travel Policies To Cuba, Carol Kline, Whitney Knollenberg, Bynum Boley, Evan Jordan

Journal of Tourism Insights

The United States and Cuba have navigated a strained political and economic relationship over the past sixty years; the tone of the relationship is in flux according to Cuban and US leadership, and most recently, COVID-19. Anticipating US travelers’ sentiments towards access to Cuba is more crucial now because of resulting policies playing out within the intersection of the shifting dynamics of the virus and the tumultuous political climate within the US. This study identified the personal factors that influence US travelers’ sentiment towards the US trade embargo and travel restrictions to Cuba. Results reveal that respondents with higher educational …

Sports Tourism In Rural Communities: Small Events, Big Impacts, Simone Silva

Journal of Tourism Insights

While the literature supports sports tourism as an effective economic development strategy, small to medium-sized rural communities often do not have the resources to promote mega sports events. This paper presents estimates of the 44^th Annual Racer Roundup College Rodeo’s economic impact. In addition to providing a case study of a relatively minor event, the aimed contribution is twofold: it offers solutions to typical challenges faced when estimating smaller-scale events’ economic impacts, and it suggests a simple way to obtain benchmark values for the magnitude of the results. Evidence suggests that the total output generated, given the cost to …

Youth Sport Influences And The American Development Model: An Analysis, Jill Fjelstul, Asli Tasci, Alan Fyall

Journal of Tourism Insights

Youth sport offers physical, mental, and social health benefits with numerous sport and recreational enterprises and venues offering respective programming of multiple sports. Participation rates of youth in sport and recreational activities, however, are declining. In addition, the age most noted to drop out of youth sport is approximately age 13. Numerous influencers impact participation and retention in youth sport. The current report examines factors impacting youth sport participation, motivation, and retention. The report also showcases seven sport governing body initiatives to strengthen youth involvement in their respective sport and could potentially offer insight to other sporting and recreational activities. …

Virtual Reality And Blogging In Tourism: Approached Towards Creating Better Tourist Experience, Anukrati Sharma, Shruti Arora

Journal of Tourism Insights

Virtual reality in tourism (virtual tourism) and blogging are highly valuable for visitors and travellers since they allow them to undertake a scouting trip before embarking on their adventure, avoid being hassled and avoid crowds while learning more about the location they are visiting or have already been. This paper provides an overview and analysis of the relationship between virtual tourism, blogging, and making the image of tourist destinations through promotion virtually and via blogs. According to the study's findings, virtual tourism cannot replace the actual experience, but it can assist in recreating it if the user has previously visited …

Impact Assessment Of Covid-19 Pandemic On Perception And Travel Behavior Of Tourists With Strategies For Resilient Recovery Of Jammu And Kashmir, India, Danish Iqbal Raina, Tanveer Nasir, Taniya Qazi

Journal of Tourism Insights

The purpose of this study is to investigate the influence of the Covid-19 pandemic on changes in tourist perceptions and travel behaviour when visiting Jammu and Kashmir during the unlocked phase of Covid-19. This study is intended to be nice. This pilot study included 208 travellers who were chosen on a non-probabilistic basis. A Chi-square test of goodness of fit, as well as content analysis, were performed on the collected data. According to the findings, the current COVID-19 epidemic will have an impact on travelers' perceptions and behaviour intentions in terms of economic expenditure, health and hygiene, modes of buying, …

Locals, Tourists, And Water Recreation Issues At Claytor Lake, Virginia, Joshua Carroll Ph.D., Ethan Hinckle

Journal of Tourism Insights

Claytor Lake is a 4,500 acre impoundment of the New River, located in southwestern Virginia and is ideal for pleasure boating, fishing, swimming, and exploration. In fall 2020 a visitor survey was administered to capture boater and adjacent landowner perceptions of the recreation experience, identify safety concerns, and help managers to informed decisions. Almost 200 surveys were collected over a month of data collection.

Results indicate that respondents tend to be a dichotomous group of “locals” who live on or within a mile of the lake, and “tourists” who travel greater than 50 miles to visit the lake. Additionally, these …

Waste Management Practices Of Small Hotels In Dehradun, Arakhita Behera, Surendra Singh Jatav

Journal of Tourism Insights

Waste has emerged as a major issue in the modern society. Due to urbanization, the volume of waste is speedily rising. If the origin of waste creation makes no effort, then all wastes are either disposed of or burnt which results in waste of land, air, water, and energy as well as the growth of undesirable animals, plants and microorganism. Through the associate and involvement of the local population, waste may be managed locally in a sustainable manner. Waste management may be an expensive endeavor if not carried out appropriately. In most of the developing nations, 20-50 percent of urban …

Returning To Travel: Fear, Coping, And Resilience During The Covid-19 Pandemic, Wilson Xieu, Jungyun "Christine" Hur, Abhijeet Shirsat

Journal of Tourism Insights

The COVID-19 pandemic has greatly affected the tourism industry, resulting in consequences such as travel fear and a decline in travel and tourism. Recognizing the needs of study in pandemic travel, this study explored individuals’ pandemic travel decision-making mechanism by investigating relationships between pandemic travel fear, coping strategies, resilience against travel fear, and pandemic travel intentions. Further, this study investigated the moderating role of risk tolerance in those relationships. The findings of this study suggest that people responded to pandemic travel fear by engaging in different types of coping strategies (e.g., task-oriented, emotion-oriented, and avoidance oriented), and through the coping …

Analysis Of Trend And Pattern Of Tourists’ Arrival: A Case Study Of Desert Tourist Circuit, Rajasthan, Sunil Manglaw, Prof. S.P. Kaushik, Manoj Khayalia

Journal of Tourism Insights

Tourism is one of the fastest-growing industries in the world economy particularly in developing countries. It is an important tool for the development of destinations’ economies and provides various socio-cultural and economic benefits such as employment generation, foreign capital exchange, infrastructure development, investment of capital, preservation of heritage sites, etc. Rajasthan is one of the most popular tourist destinations on the world’s map due to its diverse socio-cultural landscape. The desert tourist circuit has immense potential for attracting a large number of domestic as well as foreign tourists. The main aim of this study is to examine the trend and …

Lunch With Keynote - Jo Damato, Jo Damato

National Training Aircraft Symposium (NTAS)

No abstract provided.

Parole Interview Transcript/Decision - Fusl000149 (2020-09-29)

Parole Interview Transcripts and Decisions

No abstract provided.

Parole Interview Transcript/Decision - Fusl000150 (2022-04-12)

Parole Interview Transcripts and Decisions

No abstract provided.

Breaking The Cycle Of Mutual Hostility, Daniel Frost

Family Perspectives

No abstract provided.

Mindfulness In University Students: A Tool For Managing Stress, Lyndsey Kunzler

Family Perspectives

Mindfulness can be a meaningful practice across different stages of life: it can help improve well-being for young children (Becker & Whitaker, 2018; Esmaeilian et al., 2018; Li et al., 2019), adolescents (Leavitt et al., 2020; Oppo et al., 2019), and adults (Berk et al., 2018; Pierson et al., 2019). Mindfulness is the act of clearing the mind, being present, and paying attention with the intent to improve well-being (Greeson et al., 2014). Mindfulness began as a common Buddhist practice, but in the 1970s Jon Kabat-Zinn created mindfulness-based stress reduction (MBSR) in an attempt to aid mental health issues (Greeson …

Effects Of Parents’ Avoidant And Anxious Attachment On Children, Nicole Busacker

Family Perspectives

Avoidant and anxious attachment styles are both negative ways of dealing with the need for connection or bonding. One reason these attachment styles develop is in “the absence of a secure bond with an available and responsive ‘other,’ rigid, repetitive internal and interpersonal coping patterns or attachment strategies develop” (Brubacher, 2017, p. 52–53). These coping patterns are made manifest in either avoidant or anxious attachment behaviors and are mainly expressed in relation to spouses and children.

Closing

.RAW Journal of Art and Design

No abstract provided.

'Who's There', 'The Star Of The Vip Section' & 'Take A Sip', Willa Westneat, Aidan Harper

.RAW Journal of Art and Design

No abstract provided.

'Observing Others', Quincy Chan

.RAW Journal of Art and Design

No abstract provided.

'Independently Bold', 'Sisters Unarmed' & 'Birdlike Nature', Brooke De La Torre, Maddie Stein

.RAW Journal of Art and Design

No abstract provided.

'Studio A', Lela Brodie

.RAW Journal of Art and Design

No abstract provided.