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Utilizing And Implementing An Oral Health Program For Underserved Children: A Guide To Delivering A Give Kids A Smile Program, Jennifer Mckinnies Nov 2022

Utilizing And Implementing An Oral Health Program For Underserved Children: A Guide To Delivering A Give Kids A Smile Program, Jennifer Mckinnies

Research Papers

No abstract provided.


Growing As A Disciple Of Jesus: Experiencing His Presence, S. Joseph Kidder Nov 2022

Growing As A Disciple Of Jesus: Experiencing His Presence, S. Joseph Kidder

Faculty Publications

No abstract provided.


The Cost Of Being A Disciple, Anna Galeniece Nov 2022

The Cost Of Being A Disciple, Anna Galeniece

Faculty Publications

No abstract provided.


China Maritime Report No. 24: Incubators Of Sea Power: Vessel Training Centers And The Modernization Of The Plan Surface Fleet, Ryan D. Martinson Nov 2022

China Maritime Report No. 24: Incubators Of Sea Power: Vessel Training Centers And The Modernization Of The Plan Surface Fleet, Ryan D. Martinson

CMSI China Maritime Reports

The People’s Liberation Army Navy (PLAN) is building modern surface combatants faster than any other navy in the world. Before these new ships can be deployed, however, their crews must learn how to effectively operate them across the range of missions for which they were designed. In the PLAN, this “basic training” largely occurs at specialized organizations called Vessel Training Centers (VTCs). Since their creation in 1980, VTCs have played a key role in generating combat power for the fleet. But as China’s naval ambitions have grown, the VTCs have been forced to adapt. Since the early 2000s, and especially …


The Influence Of Language On Thematic Apperception Test Assessment Of Defenses In International Spanish-Speaking College Students, Ilenia Perez-Palen Nov 2022

The Influence Of Language On Thematic Apperception Test Assessment Of Defenses In International Spanish-Speaking College Students, Ilenia Perez-Palen

Theses and Dissertations

Cultural influences, including the use of language, have been shown to affect personality development and are also likely to impact personality assessment results. The influence of language is particularly relevant in story-telling measures such as the Thematic Apperception Test (TAT; Morgan & Murray, 1935). The purpose of this study was to analyze TAT narratives delivered in English and Spanish to assess the application of defense mechanisms based on the Defense Mechanism Manual (DMM; Cramer, 1991) among Hispanic international students. No study to date has provided insight into Hispanic individuals’ use of language with the TAT, specifically on scores for the …


Dll3 As An Emerging Target For The Treatment Of Neuroendocrine Neoplasms, James Yao, Emily Bergsland, Rahul Aggarwal, Ana Aparicio, Himisha Beltran, Judy S. Crabtree, Christine L. Hann, Toni Ibrahim, Lauren A. Byers, Hironobu Sasano, John Umejiego, Marianne Pavel Nov 2022

Dll3 As An Emerging Target For The Treatment Of Neuroendocrine Neoplasms, James Yao, Emily Bergsland, Rahul Aggarwal, Ana Aparicio, Himisha Beltran, Judy S. Crabtree, Christine L. Hann, Toni Ibrahim, Lauren A. Byers, Hironobu Sasano, John Umejiego, Marianne Pavel

School of Medicine Faculty Publications

Introduction: Neuroendocrine neoplasms (NEN) are heterogeneous malignancies that can arise at almost any anatomical site and are classified as biologically distinct well-differentiated neuroendocrine tumors (NET) and poorly differentiated neuroendocrine carcinomas (NEC). Current systemic therapies for advanced disease, including targeted therapies, chemotherapy, and immunotherapy, are associated with limited duration of response. New therapeutic targets are needed. One promising target is delta-like ligand 3 (DLL3), an inhibitory ligand of the Notch receptor whose overexpression on the surface of NEN is associated with tumorigenesis. Methods: This article is a narrative review that highlights the role of DLL3 in NEN progression and prognosis, the …


Letting Offenders Choose Their Punishment?, Gilles Grolleau, Murat C. Mungan, Naoufel Mzoughi Nov 2022

Letting Offenders Choose Their Punishment?, Gilles Grolleau, Murat C. Mungan, Naoufel Mzoughi

Faculty Scholarship

Punishment menus allow offenders to choose the punishment to which they will be subjected from a set of options. We present several behaviorally informed rationales for why punishment menus may serve as effective deterrents, notably by causing people to refrain from entering a calculative mindset; reducing their psychological reactance; causing them to reconsider the reputational impacts of punishment; and reducing suspicions about whether the act is enforced for rent-seeking purposes. We argue that punishment menus can outperform the traditional single punishment if these effects can be harnessed properly. Our observations thus constitute a challenge, based on behavioral arguments, to the …


Hellenic Financial Stability Fund's Annual Financial Report 2021, Hellenic Financial Stability Fund Nov 2022

Hellenic Financial Stability Fund's Annual Financial Report 2021, Hellenic Financial Stability Fund

Documents

No abstract provided.


Prompt Intervention In Large Bowel Obstruction Management: A Nationwide Inpatient Sample Analysis, Mary R. Kwaan, Yuqi Wu, Yang Ren, Sudha Xirasagar Mbbs., Ph.D. Nov 2022

Prompt Intervention In Large Bowel Obstruction Management: A Nationwide Inpatient Sample Analysis, Mary R. Kwaan, Yuqi Wu, Yang Ren, Sudha Xirasagar Mbbs., Ph.D.

Publications

BACKGROUND: Large bowel obstruction is an urgent condition which can progress to ischemia and perforation. The importance of prompt intervention has not been rigorously demonstrated. METHODS: Patients with bowel obstruction who underwent stoma, stent, and/or colectomy in the Nationwide Inpatient Sample were used to study prompt intervention (defined as occurring within 2 days of admission). Outcomes were inpatient mortality, discharge to home, and length of stay in an adjusted analysis. RESULTS: Among the 31,277 patients, prompt intervention occurred in 42.6%. In an adjusted analysis, prompt intervention was more likely in higher income patients and less likely in patients with comorbidities; …


Evaluating The Impact Of Solution-Focused Brief Therapy On Hope And Clinical Symptoms With Latine Clients, Krystle Himmelberger, James Ikonomopoulos, Javier Cavazos Vela Nov 2022

Evaluating The Impact Of Solution-Focused Brief Therapy On Hope And Clinical Symptoms With Latine Clients, Krystle Himmelberger, James Ikonomopoulos, Javier Cavazos Vela

Counseling Faculty Publications

We implemented a single-case research design (SCRD) with a small sample (N = 2) to assess the effectiveness of solution-focused brief therapy (SFBT) for Latine clients experiencing mental health concerns. Analysis of participants’ scores on the Dispositional Hope Scale (DHS) and Outcome Questionnaire (OQ-45.2) using split-middle line of progress visual trend analysis, statistical process control charting, percentage of non-overlapping data points procedure, percent improvement, and Tau-U yielded treatment effects indicating that SFBT may be effective for improving hope and mental health symptoms for Latine clients. Based on these findings, we discuss implications for counselor educators, counselors-in-training, and practitioners, which …


Mid-Simulation Debriefing: The Impact On Confidence And Clinical Judgement Of Nursing Students In A Baccalaureate Mother Baby Course, Tonya Broughton Nov 2022

Mid-Simulation Debriefing: The Impact On Confidence And Clinical Judgement Of Nursing Students In A Baccalaureate Mother Baby Course, Tonya Broughton

Graduate Theses, Dissertations, and Capstones

Debriefing is a crucial aspect of healthcare simulation. This portion of the simulation experience encompasses the vast majority of student learning and reflection that takes place, and increases skills such as communication, clinical reasoning, and critical thinking. Traditionally debriefing is performed at the end of a clinical simulation experience after the simulation experience has concluded. In the maternal-newborn setting, there are often two phases of simulation. First is the care of the laboring mother and second is the delivery and care of the newborn. This study explored the effects of completing a mid-simulation debriefing in a maternal newborn simulation at …


Development Of A Modified Screen Printed Electrode For The Determination Of Heavy Metals In Water Before And After Remediation With Food Grade Pectin And Citrofortunella Microcarpa Rinds, Shirley Palisoc, Natividad Michelle, Marissa Noel Nov 2022

Development Of A Modified Screen Printed Electrode For The Determination Of Heavy Metals In Water Before And After Remediation With Food Grade Pectin And Citrofortunella Microcarpa Rinds, Shirley Palisoc, Natividad Michelle, Marissa Noel

Angelo King Institute for Economic and Business Studies (AKI)

The rapid increase in population, urbanization, and industrialization, along with inadequate water quality monitoring and wastewater management, contribute heavily to the pollution of water resources. Among the water contaminants of major concern, heavy metals are particularly considered as the most worrisome. Heavy metals tend to accumulate in the tissues of aquatic organisms (Ahmed et al., 2019; Rajeshkumar & Li, 2018; Tabrez et al., 2021) and thus increase in concentration upon moving higher up the food chain. This indicates that once humans ingest these organisms, they have a high risk of experiencing health problems as heavy metals are absorbed into their …


Black Youths’ Perspectives: Importance Of Family And Caregiver Involvement In The Mentor–Mentee Relationship, Lakindra Mitchell Dove Nov 2022

Black Youths’ Perspectives: Importance Of Family And Caregiver Involvement In The Mentor–Mentee Relationship, Lakindra Mitchell Dove

School of Social Work Faculty Publications and Presentations

Research shows that mentorship can significantly influence the lives of youth. As a society we are becoming more diverse and aware that cultural needs for youth of color are more complex. We have seen an increase in formal mentoring programs that offer services to Black youth. As this shift continues, it is imperative that culturally responsive services are considered. Little research exists that explores the importance of family engagement within the mentor–mentee relationship. When working with Black youth, it is important to understand cultural practices found within the Black family that could have an influence on the mentor–mentee relationship. This …


The Impact Of Covid-19 On Children And Adolescents’ Mental Health, Tamara A. Hafiz, Ahmed H. Aljadani Nov 2022

The Impact Of Covid-19 On Children And Adolescents’ Mental Health, Tamara A. Hafiz, Ahmed H. Aljadani

Saudi Medical Journal

Children and adolescents are more susceptible to the formation of mental health issues, since their brains are still developing. The coronavirus disease 19 (COVID-19) pandemic response measures have disrupted daily life and left individuals socially isolated, including children and adolescents. In view of this, this study aimed to give a narrative review of the literature on the pandemic’s effects on children’s and adolescents’ mental health, associated risks, and successful intervention strategies. There are still issues to be resolved to give children and adolescents in many regions of the world with quality, rights-based, and culturally relevant mental health care. It is …


Value Of Membership-Based Free Shipping In Online Retailing: Impact Of Upstream Pricing Model, Geng Sun, Huseyin Cavusoglu, Srinivasan Raghunathan Nov 2022

Value Of Membership-Based Free Shipping In Online Retailing: Impact Of Upstream Pricing Model, Geng Sun, Huseyin Cavusoglu, Srinivasan Raghunathan

Information Systems Faculty Publications

A consumer-side innovation in online retailing is membership-based free shipping (MFS) in which a retailer bears the shipping cost for purchases made by members that have paid an upfront membership fee. On the supplier side, the agency model of selling, where a retailer allows a third-party manufacturer to sell his product on the site for a commission, has been gradually replacing the wholesale model, where the retailer buys from the manufacturer at a wholesale price and resells to consumers at a retail price. We show that the shift to the agency model enhances the value of the MFS program to …


Another Bite At The Apple Or The Same Bite? Characterizing Habeas Petitions On Appeal As Pending Instead Of Fully Adjudicated, Gregory Winder Nov 2022

Another Bite At The Apple Or The Same Bite? Characterizing Habeas Petitions On Appeal As Pending Instead Of Fully Adjudicated, Gregory Winder

William & Mary Law Review

[...] One of the Act's [Antiterrorism and Effective Death Penalty Act] most significant aspects is its restriction on the filing of successive habeas corpus petitions. Responding to this restriction, prisoners have attempted to circumvent the AEDPA through a number of different procedural routes with varying degrees of success.

This Note examines the circuit split that has emerged for one of those procedural attempts—motions to amend habeas petitions following adjudication on the merits and while on appeal in a circuit court. This Note argues that allowing amendment of habeas petitions on appeal is both consistent with the history of habeas corpus …


Table Of Contents (V. 64, No. 2) Nov 2022

Table Of Contents (V. 64, No. 2)

William & Mary Law Review

No abstract provided.


Incitement And Social Media-Algorithmic Speech: Redefining Brandenburg For A Different Kind Of Speech, Anna Rhoads Nov 2022

Incitement And Social Media-Algorithmic Speech: Redefining Brandenburg For A Different Kind Of Speech, Anna Rhoads

William & Mary Law Review

Assuming that these scholars are correct and that social media algorithms’ decisions qualify as speech to which the First Amendment applies (social media-algorithmic speech), this Note proposes a legal solution to the increasing problem of violence stemming from social media. This Note asserts that the incitement standard for social media-algorithmic speech should be less stringent because the Brandenburg standard does not apply well to new media, social media-algorithmic speech is much more likely than other speech to actually produce lawless action, and the traditional First Amendment justifications do not apply to social media algorithms’ speech. Therefore, the Supreme Court should …


Proving Copying, Shyamkrishna Balganesh, Peter S. Menell Nov 2022

Proving Copying, Shyamkrishna Balganesh, Peter S. Menell

William & Mary Law Review

Proof that a defendant actually copied from a copyrighted work is a critical part of a claim for copyright infringement. Indeed, absent such copying, there is no infringement. The most common method of proving copying involves the use of circumstantial evidence, consisting of proof that a defendant had “access” to the protected work, and a showing of “similarities” between the copy and the protected work. In inferring copying from the combination of such evidence, courts have for many decades developed a framework known as the “inverse ratio rule,” which allows them to modulate the level of proof needed on access …


Hate Speech Spikes On Twitter After Elon Musk Acquires The Platform, Bond Benton, Jin-A Choi, Yi Luo, Keith Green Nov 2022

Hate Speech Spikes On Twitter After Elon Musk Acquires The Platform, Bond Benton, Jin-A Choi, Yi Luo, Keith Green

College of Communication and Media Scholarship and Creative Works

Unmoderated social media platforms frequently become a haven for misinformation, extremism, and hate. There are challenges unique to unmoderated social media platforms that make the removal of such content and the users who spread it particularly difficult (Artime et al., 2020). When a platform’s focus is unrestricted expression from users, those looking to share and spread antisocial content will presumably use such spaces to share perspectives that would likely be restricted on other platforms. Historically, examples of such “free speech absolutist” spaces suggest that this threat is very real. Specifically, 4chan serves as a space where online anonymity coupled with …


Determinants Of Egg Consumption By Infants And Young Children In Ethiopia, Bezawit E. Kase, Edward A. Frongillo Jr. Ph.D., Sejla Isanovic, Wendy Gonzalez, Hana Yemane Wodajo, Eric W. Djmeu Nov 2022

Determinants Of Egg Consumption By Infants And Young Children In Ethiopia, Bezawit E. Kase, Edward A. Frongillo Jr. Ph.D., Sejla Isanovic, Wendy Gonzalez, Hana Yemane Wodajo, Eric W. Djmeu

Faculty Publications

Objective:

To identify determinants of egg consumption in infants and young children aged 6–23·9 months in Ethiopia. Design and setting:

Data used were from the cross-sectional baseline survey of an egg campaign in Ethiopia implemented by the Global Alliance for Improved Nutrition. Participants:

Children aged 6–23·9 months (n 453) were sampled. Data on socio-demographic characteristics, economic resources, caregiver’s behaviour, child health and feeding practices, and egg consumption in the last 7 d were collected using interviewer-administered questionnaires. Multivariable ordinal logistic regression was used to examine the association between explanatory variables and egg consumption in the last 7 d. Results:

About …


The Scoop, Vol. 9 Issue 8, November 2022, Health Sciences Library Nov 2022

The Scoop, Vol. 9 Issue 8, November 2022, Health Sciences Library

Volume 9

Latest news and updates from the Health Sciences Library in our monthly newsletter for October 2022.


Dialect Density, Language Abilities, And Emergent Literacy Skills Of Prekindergarten Children Who Speak African American English, Erika Baldwin, John J. Heilmann, Denise A. Finneran, Chi C. Cho, Maura Jones Moyle Nov 2022

Dialect Density, Language Abilities, And Emergent Literacy Skills Of Prekindergarten Children Who Speak African American English, Erika Baldwin, John J. Heilmann, Denise A. Finneran, Chi C. Cho, Maura Jones Moyle

Speech Pathology and Audiology Faculty Research and Publications

Background Numerous studies have observed a significant and unique relationship between children's use of nonmainstream dialect and reading outcomes. We aimed to examine the relationship between nonmainstream dialect and reading at its roots by completing a preliminary evaluation of the relationship between African American English (AAE) dialect and multiple dimensions of emergent literacy skills in young African American children enrolled in Head Start. Methods Seventy-eight African American preschoolers completed the Phonological Awareness Literacy Screening-PreK (PALS-PreK) and a narrative retell of the wordless picture book, Frog, Where Are You? The narratives were used to generate three measures of narrative productivity and …


Extracorporeal Membrane Oxygenation Outcomes In Children With Preexisting Neurologic Disorders Or Neurofunctional Disability, Siddhartha A Dante, Megan K Carroll, Derek K Ng, Ankur Patel, Philip C Spinella, Marie E Steiner, Laura L Loftis, Melania M Bembea Nov 2022

Extracorporeal Membrane Oxygenation Outcomes In Children With Preexisting Neurologic Disorders Or Neurofunctional Disability, Siddhartha A Dante, Megan K Carroll, Derek K Ng, Ankur Patel, Philip C Spinella, Marie E Steiner, Laura L Loftis, Melania M Bembea

Center for Medical Ethics and Health Policy Staff Publications

Objective: Patient selection for pediatric extracorporeal membrane oxygenation (ECMO) support has broadened over the years to include children with pre-existing neurologic morbidities. We aimed to determine the prevalence and nature of pre-ECMO neurologic disorders or disability and investigate the association between pre-ECMO neurologic disorders or disability and mortality and unfavorable neurologic outcome.

Design: Multicenter retrospective observational cohort study.

Setting: Eight hospitals reporting to the Pediatric ECMO Outcomes Registry between October 2011 and June 2019.

Patients: Children younger than 18 years supported with venoarterial or venovenous ECMO.

Interventions: The primary exposure was presence of pre-ECMO neurologic disorders or moderate-to-severe disability, defined …


Safety Analysis Of High-Dose Methotrexate In Pediatric Non-Hodgkin Lymphomas, M Brooke Bernhardt, Austin L Brown, Austyn T Grim, Michael E Scheurer, Nader Kim El-Mallawany, Nmazuo W Ozuah Nov 2022

Safety Analysis Of High-Dose Methotrexate In Pediatric Non-Hodgkin Lymphomas, M Brooke Bernhardt, Austin L Brown, Austyn T Grim, Michael E Scheurer, Nader Kim El-Mallawany, Nmazuo W Ozuah

Center for Medical Ethics and Health Policy Staff Publications

High-dose methotrexate (HD-MTX) with rigorous supportive care is essential to the treatment of pediatric non-Hodgkin lymphomas (NHL). We describe the safety and tolerability of HD-MTX in patients with NHL treated at our center. In our cohort of 46 patients, the majority had at least one course of delayed clearance and/or creatinine elevation. Additionally, more than one-third of patients experienced an episode of grade ≥3 mucositis. Creatinine elevations and delayed clearance were independently associated with subsequent grade ≥3 mucositis. We advocate for greater availability of methotrexate monitoring to allow dose escalation of this essential modality around the world.


Medicaid Expansion And Veterans' Reliance On The Va For Depression Care, Daniel Liaou, Patrick N O'Mahen, Laura A Petersen Nov 2022

Medicaid Expansion And Veterans' Reliance On The Va For Depression Care, Daniel Liaou, Patrick N O'Mahen, Laura A Petersen

Center for Medical Ethics and Health Policy Staff Publications

Background: In 2001, before the Affordable Care Act (ACA), some states expanded Medicaid coverage to include an array of mental health services, changing veterans' reliance on US Department of Veterans Affairs (VA) services.

Methods: Using Medicaid and VA administrative data from 1999 to 2006, we used a difference-in-difference design to calculate shifts in veterans' reliance on the VA for depression care in New York and Arizona after the 2 states expanded Medicaid coverage to adults in 2001. Demographically matched, neighbor states Pennsylvania and New Mexico/Nevada were used as paired comparisons, respectively. Fractional logit was used to capture the distribution of …


Evolution Of Severe Acute Respiratory Coronavirus Virus 2 (Sars-Cov-2) Seroprevalence Among Employees Of A Us Academic Children’S Hospital During Coronavirus Disease 2019 (Covid-19) Pandemic, Brian T Fisher, Anna Sharova, Craig L K Boge, Sigrid Gouma, Audrey Kamrin, Jesse Blumenstock, Sydney Shuster, Lauren Gianchetti, Danielle Collins, Elikplim Akaho, Madison E Weirick, Christopher M Mcallister, Marcus J Bolton, Claudia P Arevalo, Eileen C Goodwin, Elizabeth M Anderson, Shannon R Christensen, Fran Balamuth, Audrey R Odom John, Yun Li, Susan Coffin, Jeffrey S Gerber, Scott E Hensley Nov 2022

Evolution Of Severe Acute Respiratory Coronavirus Virus 2 (Sars-Cov-2) Seroprevalence Among Employees Of A Us Academic Children’S Hospital During Coronavirus Disease 2019 (Covid-19) Pandemic, Brian T Fisher, Anna Sharova, Craig L K Boge, Sigrid Gouma, Audrey Kamrin, Jesse Blumenstock, Sydney Shuster, Lauren Gianchetti, Danielle Collins, Elikplim Akaho, Madison E Weirick, Christopher M Mcallister, Marcus J Bolton, Claudia P Arevalo, Eileen C Goodwin, Elizabeth M Anderson, Shannon R Christensen, Fran Balamuth, Audrey R Odom John, Yun Li, Susan Coffin, Jeffrey S Gerber, Scott E Hensley

Staff and Researcher Publications

Objective: To describe the cumulative seroprevalence of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) antibodies during the coronavirus disease 2019 (COVID-19) pandemic among employees of a large pediatric healthcare system.

Design, setting, and participants: Prospective observational cohort study open to adult employees at the Children's Hospital of Philadelphia, conducted April 20-December 17, 2020.

Methods: Employees were recruited starting with high-risk exposure groups, utilizing e-mails, flyers, and announcements at virtual town hall meetings. At baseline, 1 month, 2 months, and 6 months, participants reported occupational and community exposures and gave a blood sample for SARS-CoV-2 antibody measurement by enzyme-linked immunosorbent assays …


Oxytocin Signaling Is Necessary For Synaptic Maturation Of Adult-Born Neurons, Brandon T Pekarek, Mikhail Kochukov, Brittney Lozzi, Timothy Wu, Patrick J Hunt, Burak Tepe, Elizabeth Hanson Moss, Evelyne K Tantry, Jessica L Swanson, Sean W Dooling, Mayuri Patel, Benjamin D W Belfort, Juan M Romero, Suyang Bao, Matthew C Hill, Benjamin R Arenkiel Nov 2022

Oxytocin Signaling Is Necessary For Synaptic Maturation Of Adult-Born Neurons, Brandon T Pekarek, Mikhail Kochukov, Brittney Lozzi, Timothy Wu, Patrick J Hunt, Burak Tepe, Elizabeth Hanson Moss, Evelyne K Tantry, Jessica L Swanson, Sean W Dooling, Mayuri Patel, Benjamin D W Belfort, Juan M Romero, Suyang Bao, Matthew C Hill, Benjamin R Arenkiel

Duncan NRI Faculty and Staff Publications

Neural circuit plasticity and sensory response dynamics depend on forming new synaptic connections. Despite recent advances toward understanding the consequences of circuit plasticity, the mechanisms driving circuit plasticity are unknown. Adult-born neurons within the olfactory bulb have proven to be a powerful model for studying circuit plasticity, providing a broad and accessible avenue into neuron development, migration, and circuit integration. We and others have shown that efficient adult-born neuron circuit integration hinges on presynaptic activity in the form of diverse signaling peptides. Here, we demonstrate a novel oxytocin-dependent mechanism of adult-born neuron synaptic maturation and circuit integration. We reveal spatial …


Race, Racism, And Antiracism In Emergency Medicine: A Scoping Review Of The Literature And Research Agenda For The Future, Anna Darby, Emily C Cleveland Manchanda, Hannah Janeway, Shamsher Samra, Marquita Norman Hicks, Ruby Long, Katrina A Gipson, Anita N Chary, Brenda A Adjei, Kajal Khanna, Ava Pierce, Sheri-Ann O Kaltiso, Sophia Spadafore, Jennifer Tsai, Annette Dekker, Molly E Thiessen, Jordan Foster, Rose Diaz, Mikaela Mizuno, Elizabeth Schoenfeld Nov 2022

Race, Racism, And Antiracism In Emergency Medicine: A Scoping Review Of The Literature And Research Agenda For The Future, Anna Darby, Emily C Cleveland Manchanda, Hannah Janeway, Shamsher Samra, Marquita Norman Hicks, Ruby Long, Katrina A Gipson, Anita N Chary, Brenda A Adjei, Kajal Khanna, Ava Pierce, Sheri-Ann O Kaltiso, Sophia Spadafore, Jennifer Tsai, Annette Dekker, Molly E Thiessen, Jordan Foster, Rose Diaz, Mikaela Mizuno, Elizabeth Schoenfeld

Faculty, Staff and Students Publications

Objectives: The objective was to conduct a scoping review of the literature and develop consensus-derived research priorities for future research inquiry in an effort to (1) identify and summarize existing research related to race, racism, and antiracism in emergency medicine (EM) and adjacent fields and (2) set the agenda for EM research in these topic areas.

Methods: A scoping review of the literature using PubMed and EMBASE databases, as well as review of citations from included articles, formed the basis for discussions with community stakeholders, who in turn helped to inform and shape the discussion and recommendations of participants in …


A New Mouse Model Of Charcot-Marie-Tooth 2j Neuropathy Replicates Human Axonopathy And Suggest Alteration In Axo-Glia Communication, Ghjuvan'ghjacumu Shackleford, Yo Sasaki, Et Al. Nov 2022

A New Mouse Model Of Charcot-Marie-Tooth 2j Neuropathy Replicates Human Axonopathy And Suggest Alteration In Axo-Glia Communication, Ghjuvan'ghjacumu Shackleford, Yo Sasaki, Et Al.

2020-Current year OA Pubs

Myelin is essential for rapid nerve impulse propagation and axon protection. Accordingly, defects in myelination or myelin maintenance lead to secondary axonal damage and subsequent degeneration. Studies utilizing genetic (CNPase-, MAG-, and PLP-null mice) and naturally occurring neuropathy models suggest that myelinating glia also support axons independently from myelin. Myelin protein zero (MPZ or P0), which is expressed only by Schwann cells, is critical for myelin formation and maintenance in the peripheral nervous system. Many mutations in MPZ are associated with demyelinating neuropathies (Charcot-Marie-Tooth disease type 1B [CMT1B]). Surprisingly, the substitution of threonine by methionine at position 124 of P0 …