Digital Commons Network^™

Mindfulness Based Stress Reduction Techniques In Chronic Illness, Anna Celia Gil

Electronic Theses and Dissertations

Abstract

Chronic stress and its effect on both physical and mental health have been a topic of increasing interest in the past several decades. There is mounting evidence that recurrent, persistent stress of both a physiologic and psychological nature leads to a dysfunction in the hypothalamic pituitary axis (HPA), the system which helps the body recover and adapt to short term stress. In long term stress, this HPA dysfunction leads to impairment of the immune and neuroendocrine systems resulting in chronic low-grade inflammation. This type of chronic inflammation acts as a precursor to several chronic illnesses such as diabetes, hypertension, …

Exploring A Cooperative Learning Model With A Mixed Methods Design, Zhidong Zhang, Liza Ramos

Teaching and Learning Faculty Publications

The exploratory sequential design was used in this study. The mixed methods design consisted of two modules: a qualitative module and a quantitative module. The qualitative module was used to code the data into categories and further into the structure in terms of Saldana’s model. Based on the analysis of the interview transcripts, three themes were recognized to support the cooperative learning models. These three themes were Knowing by Undergone Events and Contexts (KUEC), Implementation and Action (I&A), and Opinions and Perceptions (OP). These three themes consisted of a Collaborative Learning Model describing and evaluating different topic patterns.

Fixed-Dose Combination Therapy-Based Protocol Compared With Free Pill Combination Protocol: Results Of A Cluster Randomized Trial, Olutobi A Sanuade, Mark D Huffman, Et Al.

2020-Current year OA Pubs

Fixed-dose combination (FDC) therapy is recommended for hypertension management in Nigeria based on randomized trials at the individual level. This cluster-randomized trial evaluates effectiveness and safety of a treatment protocol that used two-drug FDC therapy as the second and third steps for hypertension control compared with a protocol that used free pill combinations. From January 2021 to June 2021, 60 primary healthcare centers in the Federal Capital Territory of Nigeria were randomized to a protocol using FDC therapy as second and third steps compared with a protocol that used the same medications in free pill combination therapy for these steps. …

Lgmdd1 Natural History And Phenotypic Spectrum: Implications For Clinical Trials, Andrew R Findlay, Sarah E Robinson, Stephanie Poelker, Michelle Seiffert, Rocio Bengoechea, Conrad C Weihl

2020-Current year OA Pubs

OBJECTIVE: To delineate the full phenotypic spectrum and characterize the natural history of limb girdle muscular dystrophy type D1 (LGMDD1).

METHODS: We extracted age at clinical events of interest contributing to LGMDD1 disease burden via a systematic literature and chart review. Manual muscle testing and quantitative dynamometry data were used to estimate annualized rates of change. We also conducted a cross-sectional observational study using previously validated patient-reported outcome assessments (ACTIVLIM, PROMIS-57) and a new LGMDD1 questionnaire. Some individuals underwent repeat ACTIVLIM and LGMDD1 questionnaire assessments at 1.5 and 2.5 years.

RESULTS: A total of 122 LGMDD1 patients were included from …

The Insurance Landscape For Implant- And Autologous-Based Breast Reconstruction In The United States, Louisa C. Boyd, Jason A. Greenfield, Sravya S. Ainapurapu, Rachel Skladman, Gary Skolnick, Durai Sundaramoorthi, Justin M. Sacks

2020-Current year OA Pubs

UNLABELLED: Insurance coverage of postmastectomy breast reconstruction is mandated in America, regardless of reconstructive modality. Despite enhanced patient-reported outcomes, autologous reconstruction is utilized less than nonautologous reconstruction nationally. Lower reimbursement from Medicare and Medicaid may disincentivize autologous-based reconstruction. This study examines the impact of insurance and sociodemographic factors on breast reconstruction.

METHODS: A retrospective analysis of the Healthcare Cost and Utilization Project National Inpatient Sample Database from 2014 to 2017 was performed. International Classification of Diseases Clinical Modification and Procedure Coding System codes were used to identify patients for inclusion. De-identified sociodemographic and insurance data were analyzed using

RESULTS: In …

Autophagy Requirements For Eye Lens Differentiation And Transparency, Lisa Brennan, M Joseph Costello, J Fielding Hejtmancik, A Sue Menko, S Amer Riazuddin, Alan Shiels, Marc Kantorow

2020-Current year OA Pubs

Recent evidence points to autophagy as an essential cellular requirement for achieving the mature structure, homeostasis, and transparency of the lens. Collective evidence from multiple laboratories using chick, mouse, primate, and human model systems provides evidence that classic autophagy structures, ranging from double-membrane autophagosomes to single-membrane autolysosomes, are found throughout the lens in both undifferentiated lens epithelial cells and maturing lens fiber cells. Recently, key autophagy signaling pathways have been identified to initiate critical steps in the lens differentiation program, including the elimination of organelles to form the core lens organelle-free zone. Other recent studies using ex vivo lens culture …

Toxin Induced Parkinsonism And Hospitalization Related Adverse Outcome Mitigation For Parkinson’S Disease: A Comprehensive Review, Kenneth R. Dalton, Charles J. Kidd, Nawaz Hack

School of Medicine Publications

Patients with Parkinson’s disease admitted to the hospital have unique presentations. This unique subset of patients requires a multidisciplinary approach with a knowledge-based care team that can demonstrate awareness of complications specific to Parkinson’s disease to reduce critical care admissions, morbidity, and mortality. Early recognition of toxic exposures, medication withdrawals, or medication-induced symptoms can reduce morbidity and mortality. This review can assist in the critical assessment of new or exacerbating Parkinson’s disease symptoms.

Ash Aerosol Particle Size Distribution, Composition, And Deposition Behavior While Co-Firing Coal And Steam-Exploded Biomass In A 1.5 Mwth Combustor, Rajarshi Roy, Brian Schooff, Xiaolong Li, Scott Montgomery, Jacob Tuttle, Jost O.L. Wendt, Kingsley Dickson, Brian Iverson, Andrew R. Fry

Faculty Publications

Five different blends of Utah bituminous coal and steam-exploded pine (100/0, 75/25, 50/50, 25/75, 0/100 by mass) were fired in a 1.5 MWth combustor. Primary objectives were to understand mineral matter behavior by analyzing aerosol size distribution, aerosol size-segregated composition, ash deposition mass, and ash composition. For particle size < 0.1 μm, pure coal had the lowest aerosol concentration and pure biomass showed the highest (higher nucleation of potassium salts), a trend which reversed for particles >0.1 μm. During pure biomass combustion, aerosol particles >15 μm contained higher mass fractions of potassium (+126%), calcium (+132%), and iron (+115%) and lower fractions of aluminum (−49%) and silicon (−29%) than pure coal. Ash deposition mass decreased with increasing biomass blends. …

Forgotten Brother Reuben Lewis: Missouri River Fur Trader And Indian Agent For The Arkansas Cherokees, Jay H. Buckley, Deveney Reber

Faculty Publications

Reuben Lewis was born in 1777, the fourth and youngest child of William Lewis and Lucy Meriwether. Their oldest child, Jane, married and lived out her days at Locust Hill, the family estate in Virginia. The Lewis’ second child, baby Lucinda, died in infancy. Their third child, Meriwether – the closest in age and friendship to Reuben – became the famous first half of the Lewis and Clark Expedition which explored the uncharted West before he met his tragic and mysterious death on the Natchez Trace in Tennessee. While Reuben’s life has been rightly overshadowed by his older brother Meriwether’s …

Examination Of Korean Feminism From The Intersections Of Colonialism, Modernity, And Nationalism In Colonial Korea (1910–1945), Yae Hee Choi

Dissertations, Theses, and Capstone Projects

This thesis aims to investigate the politics of Korean feminism during the time of Japanese colonization (1910-1945) from the perspectives of colonialism, modernity, and nationalism. The study illustrates how Korean women perceived themselves in terms of individuals, colonial subjects, and Korean nationals during a period of significant societal changes. It also intends to broaden the boundaries of gender inquiries in colonial Korea, which often focus on binary constructions of Japanese repression versus national resistance. This study argues that a nationalist paradigm oversimplifies the intricate dynamics and varied experiences of colonized subjects, specifically women. The logic of nationalism places all forms …

Police Academy Attrition Rates: A Long-Term Analysis Of Female Candidates In California, Texas, Wisconsin, Arizona, And New Jersey, Shamus W. Smith

Dissertations, Theses, and Capstone Projects

Police agencies throughout the country still have an underrepresentation of women police officers. Research has shown that the benefits of hiring women police officers are many, as they have proven to be as competent as their male counterparts, less likely to use excessive force, can implement community-oriented policing, respond to calls for domestic violence effectively, bring about beneficial changes in policy for all agencies, and reduce the problems of sexual discrimination and harassment within an agency. Yet, the obstacles encountered for women are significantly different from their male counterparts. As such, this research uses secondary, non-identifiable data obtained from police …

Analysis Of Electrophysiological Markers And Correlated Components Of Neural Responses To Discourse Coherence, Kurt M. Masiello

Dissertations, Theses, and Capstone Projects

Constructing meaning from spoken language is invaluable for learning, social interaction, and communication. In clinical populations with developmental disorders of speech comprehension, the severity of disruption can persist and vary from limiting occupational opportunities to lower performance outcomes. Previous research has reported an event-related potential (ERP) neural positivity over right hemisphere lateral anterior sites in response to semantic and discourse processing. Although useful as a marker for clinical populations of autism spectrum disorder (ASD) and developmental language disorder (DLD), little is understood about the dynamics and neural sources of this biological marker. In addition to traditional methods of ERP analysis, …

Storytelling In Modernist Fiction: A “Method Of Presence”, Laura Malhotra

Dissertations, Theses, and Capstone Projects

This dissertation explores the relationship between narrative modes in cinema and literature and adopts the lineage laid out by Lukács that connects the oral tradition and epic poetry to the novel. I attach art cinema to this lineage and seek to justify its position as an equally significant medium representative of the age in which it is produced. This study aims to correct one established view of film, put forth by the Frankfurt School, of its low value as an art form and as a site of meaning. I compare the birth of literary modernism in Britain to the emergence …

Indigenous Performances In Contemporary Indian Urban Public Theatres: Coloniality, Globalization, And The State, Mayurakshi Sen

Dissertations, Theses, and Capstone Projects

Indigenous Performances in Contemporary Indian Urban Public Theatres: Coloniality, Globalization, and the State examines the aesthetic and political dimensions of contemporary public theatres in the major Indian cities of Kolkata, Mumbai, and Delhi, with a special focus on the utilization of India’s indigenous precolonial (or extra-colonial) classical, regional, and folk performance forms, elements, and repertoires in such urban practice. Through dramaturgical, ethnographic, and archival analyses, this dissertation studies significant contemporary productions from representative urban Indian theatre groups, including Nandikar, Rangakarmee, and Padatik in Kolkata; the Indian People’s Theatre Association, Mumbai, Ekjute, and Rangshila in Mumbai; and Circle Theatre Company and …

Origin And Evolution Of Marsupial-Specific Imprinting Clusters Through Lineage-Specific Gene Duplications And Acquisition Of Promoter Differential Methylation, Wenqi Cao, Kory C. Douglas, Paul B. Samollow, John Vandeberg, Xu Wang, Andrew G. Clark

School of Medicine Publications

Genomic imprinting is a parent-of-origin-specific expression phenomenon that plays fundamental roles in many biological processes. In animals, imprinting is only observed in therian mammals, with ∼200 imprinted genes known in humans and mice. The imprinting pattern in marsupials has been minimally investigated by examining orthologs to known eutherian imprinted genes. To identify marsupial-specific imprinting in an unbiased way, we performed RNA-seq studies on samples of fetal brain and placenta from the reciprocal cross progeny of two laboratory opossum stocks. We inferred allele-specific expression for >3,000 expressed genes and discovered/validated 13 imprinted genes, including three previously known imprinted genes, Igf2r, Peg10, …

Multi-Ancestry Transcriptome-Wide Association Analyses Yield Insights Into Tobacco Use Biology And Drug Repurposing, Fang Cheng, Xingyan Wang, Seon-Kyeong Jang, Bryan C. Quach, J. Dylan Weissenkampen, Chachrit Khunsriraksakul, Lina Yang, John Blangero, Joanne E. Curran, Ravindranath Duggirala, Juan M. Peralta

School of Medicine Publications

Most transcriptome-wide association studies (TWASs) so far focus on European ancestry and lack diversity. To overcome this limitation, we aggregated genome-wide association study (GWAS) summary statistics, whole-genome sequences and expression quantitative trait locus (eQTL) data from diverse ancestries. We developed a new approach, TESLA (multi-ancestry integrative study using an optimal linear combination of association statistics), to integrate an eQTL dataset with a multi-ancestry GWAS. By exploiting shared phenotypic effects between ancestries and accommodating potential effect heterogeneities, TESLA improves power over other TWAS methods. When applied to tobacco use phenotypes, TESLA identified 273 new genes, up to 55% more compared with …

The Effect Of An American Heart Association–Approved Exercise Regimen On Burnout In Nurse Practitioners And Physician Assistants Working In Emergency Departments, Michelle Lee Johnson

Electronic Theses and Dissertations

Burnout is a widely known state of physical and emotional fatigue previously noted to affect as many as 60% of healthcare providers, but one that is understudied in nurse practitioners and physician assistants working in emergency departments. It is imperative that the providers of healthcare recognize in themselves signs of burnout and have resources available to mitigate the condition. A pretest–posttest, quasi-experimental, nonequivalent control group, descriptive research design with descriptive statistics analysis was used to analyze answers to an email-based survey sent to nurse practitioners and physician assistants working for one large emergency medicine staffing company. The intent of this …

The Perceptions Of Faculty And Instructional Designers Regarding The Impact Of Professional Development To Teach Online Courses, Scott Mitchell January

Electronic Theses and Dissertations

Leadership at a mid-sized 4-year university in the western region of Texas asserted a problem with the low amount of faculty training impacting online courses’ creation and quality. The purpose of this qualitative single case study was to investigate the elements needed to design quality online courses, determine how faculty and instructional designers perceived professional development provided by the university to develop online courses, and find out how faculty and instructional designers perceived professional development impacted faculty skills as an online instructor. Three research questions were created which generated two interview protocols. The following research questions were used and were …

Examining Leadership Experiences And Practices Of African American Women In Higher Education Settings To Overcome Barriers, Tanya Stubbs White

Electronic Theses and Dissertations

Abstract: This qualitative case study described the steps 11 African American women have practiced in growing and continuing their path to notable success in higher education leadership. No one size will fit all, but the methods used by African American women may guide other African American or culturally diverse women on how to transcend into and ascertain the well-deserved leadership roles in higher education administration or faculty careers. This study provided narratives of the women leaders to explain their journey to a leadership role. The purpose of the study was to describe the path, barriers, and supports that African American …

The Present And Future Status Of Heavy Neutral Leptons, Asli M. Abdullahi, Pablo Barham Alzás, Brian Batell, James Beacham, Alexey Boyarsky, Saneli Carbajal, Animesh Chatterjee, José I. Crespo-Anadón, Frank F. Deppisch, Albert De Roeck, Marco Drewes, Alberto Martin Gago, Rebeca Gonzalez Suarez, Evgueni Goudzovski, Athanasios Hatzikoutelis, Josu Hernandez-Garcia, Matheus Hostert, Marco Hufnagel, Philip Ilten

Faculty Research, Scholarly, and Creative Activity

The existence of nonzero neutrino masses points to the likely existence of multiple Standard Model neutral fermions. When such states are heavy enough that they cannot be produced in oscillations, they are referred to as heavy neutral leptons (HNLs). In this white paper, we discuss the present experimental status of HNLs including colliders, beta decay, accelerators, as well as astrophysical and cosmological impacts. We discuss the importance of continuing to search for HNLs, and its potential impact on our understanding of key fundamental questions, and additionally we outline the future prospects for next-generation future experiments or upcoming accelerator run scenarios.

Student Awareness Of Models In First-Year Engineering Courses, Farshid Marbouti, Kelsey J. Rodgers, Angela K. Thompson, Matthew Verleger, Nicholas Hawkins

Faculty Research, Scholarly, and Creative Activity

Contribution: This study assesses more than 800 students' awareness of engineering model types before and after taking two first-year engineering courses across two semesters and evaluates the effect of each course. Background: All engineers must be able to apply and create models to be effective problem solvers, critical thinkers, and innovative designers. To help them develop these skills, as a first step, it is essential to assess how to increase students' awareness of engineering models. According to Bloom's taxonomy, the lower remember and understand levels, which encompass awareness, are necessary for achieving the higher levels, such as apply, analyze, evaluate, …

Constrained Reinforcement Learning In Hard Exploration Problems, Pankayaraj Pathmanathan, Pradeep Varakantham

Research Collection School Of Computing and Information Systems

One approach to guaranteeing safety in Reinforcement Learning is through cost constraints that are imposed on trajectories. Recent works in constrained RL have developed methods that ensure constraints can be enforced even at learning time while maximizing the overall value of the policy. Unfortunately, as demonstrated in our experimental results, such approaches do not perform well on complex multi-level tasks, with longer episode lengths or sparse rewards. To that end, wepropose a scalable hierarchical approach for constrained RL problems that employs backward cost value functions in the context of task hierarchy and a novel intrinsic reward function in lower levels …

Future Aware Pricing And Matching For Sustainable On-Demand Ride Pooling, Xianjie Zhang, Pradeep Varakantham, Hao Jiang

Research Collection School Of Computing and Information Systems

The popularity of on-demand ride pooling is owing to the benefits offered to customers (lower prices), taxi drivers (higher revenue), environment (lower carbon footprint due to fewer vehicles) and aggregation companies like Uber (higher revenue). To achieve these benefits, two key interlinked challenges have to be solved effectively: (a) pricing – setting prices to customer requests for taxis; and (b) matching – assignment of customers (that accepted the prices) to taxis/cars. Traditionally, both these challenges have been studied individually and using myopic approaches (considering only current requests), without considering the impact of current matching on addressing future requests. In this …

Human-Centered Ai For Software Engineering: Requirements, Reflection, And Road Ahead, David Lo

Research Collection School Of Computing and Information Systems

Since its inception in the 2000s, AI for Software Engineering (AI4SE) has grown rapidly. AI in its different forms, e.g., data mining, information retrieval, machine learning, natural language processing, etc., has been demonstrated to be able to produce good results for automating many tasks, including specification mining, bug and vulnerability discovery, bug localization, duplicate bug report identification, failure detection, program repair, technical question answering, code search, and many more. AI4SE has much potential to improve software engineers’ productivity and software quality. Due to its potential, it is currently one of the most popular research areas in the software engineering field.To …

An Empirical Study Of Package Management Issues Via Stack Overflow, Syful Islam, Raula Kula, Christoph Treude, Bodin Chinthanet, Takashi Ishio, Kenichi Matsumoto

Research Collection School Of Computing and Information Systems

The package manager (PM) is crucial to most technology stacks, acting as a broker to ensure that a verified dependency package is correctly installed, configured, or removed from an application. Diversity in technology stacks has led to dozens of PMs with various features. While our recent study indicates that package management features of PM are related to end-user experiences, it is unclear what those issues are and what information is required to resolve them. In this paper, we have investigated PM issues faced by end-users through an empirical study of content on Stack Overflow (SO). We carried out a qualitative …

A Molecular Signature Defining Exercise Adaptation With Ageing And In Vivo Partial Reprogramming In Skeletal Muscle, Ronald G. Jones Iii, Andrea Dimet-Wiley, Amin Haghani, Francielly Morena Da Silva, Camille R. Brightwell, Seongkyun Lim, Sabin Khadgi, Yuan Wen, Corey M. Dungan, Robert T. Brooke, Nicholas P. Greene, Charlotte A. Peterson, John J. Mccarthy, Steve Horvath, Stanley J. Watowich, Christopher S. Fry, Kevin A. Murach

Health, Human Performance and Recreation Faculty Publications and Presentations

Exercise promotes functional improvements in aged tissues, but the extent to which it simulates partial molecular reprogramming is unknown. Using transcriptome profiling from (1) a skeletal muscle-specific in vivo Oct3/4, Klf4, Sox2 and Myc (OKSM) reprogramming-factor expression murine model; (2) an in vivo inducible muscle-specific Myc induction murine model; (3) a translatable high-volume hypertrophic exercise training approach in aged mice; and (4) human exercise muscle biopsies, we collectively defined exercise-induced genes that are common to partial reprogramming. Late-life exercise training lowered murine DNA methylation age according to several contemporary muscle-specific clocks. A comparison of the murine soleus transcriptome …

Extended Training Improves The Accuracy And Efficiency Of Goal-Directed Reaching Guided By Supplemental Kinesthetic Vibrotactile Feedback, Valay A. Shah, Ashiya Thomas, Leigh A. Mrotek, Maura Casadio, Robert A. Scheidt

Biomedical Engineering Faculty Research and Publications

Prior studies have shown that the accuracy and efficiency of reaching can be improved using novel sensory interfaces to apply task-specific vibrotactile feedback (VTF) during movement. However, those studies have typically evaluated performance after less than 1 h of training using VTF. Here, we tested the effects of extended training using a specific form of vibrotactile cues—supplemental kinesthetic VTF—on the accuracy and temporal efficiency of goal-directed reaching. Healthy young adults performed planar reaching with VTF encoding of the moving hand's instantaneous position, applied to the non-moving arm. We compared target capture errors and movement times before, during, and after approximately …

Gender Inequality Against Women Fishers In Indonesia, Ani Purwanti, Dyah Wijaningsih, Muh. Afif Mahfud, Aga Natalis

Indonesia Law Review

This study explores whether or not Law No. 7 of 2016 for the Protection and Empowerment of Fishermen, Fish Cultivators, and Salt Farmers discriminates against women. This law supports small fishermen since it requires the government to provide them with financial stability through harvest season output guarantees. On the other hand, we discovered that Law No. 7 of 2016, about the Protection and Empowerment of Fishermen, Fish Cultivators, and Salt Farmers, has discriminatory consequences damaging the welfare of female fishermen. Because of sociological and cultural bias, female fishermen are the most neglected segment in the fishing sector. This is in …

Kasus Wang Renshu: Sebuah Kegagalan Diplomasi Rrc Terhadap Indonesia, Tuty Enoch Muas

Paradigma: Jurnal Kajian Budaya

The Chinese-Indonesian relations in 1951 was in tension due the actions of Ambassador Wang Renshu. As China was not favored in the international arena for its communist stand, the Chinese citizens in Indonesia became important factor in the relations between China and Indonesia where they were divided into taking side with either the communists or the capitalists. Wang Renshu, a senior member in the China Communist Party, has recruited between six and seven hundred thousand Indonesians of Chinese ancestry to adopt Chinese citizenship, of which it became a threat to the Chinese-Indonesian diplomatic relations. The withdrawal of Ambassador Wang Renshu …

Administrative Appeal Decision - Young, Scott (2022-11-14)

Parole Administrative Appeal Decisions

No abstract provided.