Digital Commons Network^™

Myo/Nog Cells Give Rise To Myofibroblasts During Epiretinal Membrane Formation In A Mouse Model Of Proliferative Vitreoretinopathy., Mara Crispin, Jacquelyn Gerhart, Alison Heffer, Mark Martin, Fathma Abdalla, Arturo Bravo Nuevo, Nancy J Philp, Ajay E Kuriyan, Mindy George-Weinstein

PCOM Scholarly Works

PURPOSE: Myo/Nog cells are the source of myofibroblasts in the lens and synthesize muscle proteins in human epiretinal membranes (ERMs). In the current study, we examined the response of Myo/Nog cells during ERM formation in a mouse model of proliferative vitreoretinopathy (PVR).

METHODS: PVR was induced by intravitreal injections of gas and ARPE-19 cells. PVR grade was scored by fundus imaging, optical coherence tomography, and histology. Double label immunofluorescence localization was performed to quantify Myo/Nog cells, myofibroblasts, and leukocytes.

RESULTS: Myo/Nog cells, identified by co-labeling with antibodies to brain-specific angiogenesis inhibitor 1 (BAI1) and Noggin, increased throughout the eye with …

Design And Characterization Of An Aerosol Test Chamber For Emergency Response Patient Contamination Control Simulation And Research, Megan L. Steele, Emily M. Spatz, George P. Lemmer, Jacob M. Denney, Casey Cooper, Jeremy M. Slagley, Robert M. Eninger

Faculty Publications

Contaminated or infected patients present a risk of cross-contamination for emergency responders, attending medical personnel and medical facilities as they enter a treatment facility. The controlled conditions of an aerosol test chamber are required to examine factors of contamination, decontamination, and cross-contamination. This study presents the design, construction, and a method for characterizing an aerosol test chamber for a full-sized manikin on a standard North Atlantic Treaty Organization litter. The methodology combined air velocity measurements, aerosol particle counts and size distributions, and computational fluid dynamics modeling to describe the chamber’s performance in three dimensions. This detailed characterization facilitates future experimental …

Ypfs Lessons Learned Oral History Project: An Interview With Jeremy Rudin, Jeremy Rudin, Rosalind Wiggins, Mary Anne Chute Lynch

Documents

No abstract provided.

The Health And Social Impacts Of An Ageing Population In Singapore, And Why It Matters, Paulin Tay Straughan, Chongsheng, Micah (Chen Chongsheng) Tan

Research Collection School of Social Sciences

Singapore’s population is ageing rapidly, with the National Population and Talent Division estimating that about one in four Singaporeans will be aged 65 and above by 2030 (National Population and Talent Division 2022). It is anticipated that these demographic changes will have wide-reaching implications for the country that will span all sectors and dimensions of society. In this article, we focus in on two specific dimensions of the impact that an ageing population will have for society; health and social impacts. Using data from the Singapore Life Panel® (SLP) that has been running for the past seven years at the …

Applying Landscape Metrics To Species Distribution Model Predictions To Characterize Internal Range Structure And Associated Changes, A Curd, M Chevalier, M Vasquez, A Boyé, Et Al

School of Biological and Marine Sciences

Distributional shifts in species ranges provide critical evidence of ecological responses to climate change. Assessments of climate-driven changes typically focus on broad-scale range shifts (e.g. poleward or upward), with ecological consequences at regional and local scales commonly overlooked. While these changes are informative for species presenting continuous geographic ranges, many species have discontinuous distributions—both natural (e.g. mountain or coastal species) or human-induced (e.g. species inhabiting fragmented landscapes)—where within-range changes can be significant. Here, we use an ecosystem engineer species (Sabellaria alveolata) with a naturally fragmented distribution as a case study to assess climate-driven changes in within-range occupancy across its entire …

Wayne E. Sabbe Arkansas Soil Fertility Studies 2022, Nathan A. Slaton, Mike Daniels

Arkansas Agricultural Experiment Station Research Series

Rapid technological changes in crop management and production require that the research efforts be presented in an expeditious manner. The contributions of soil fertility and fertilizers are major production factors in all Arkansas crops. The studies described within will allow producers to compare their practices with the university’s research efforts. Additionally, soil-test data and fertilizer sales are presented to allow comparisons among years, crops, and other areas within Arkansas.

Annual Report 2022, Novo Banco S.A.

Documents

No abstract provided.

Genomic Or Non-Genomic? A Question About The Pleiotropic Roles Of Vitamin D In Inflammatory-Based Diseases, Michael F. Holick, Luciana Mazzei, Sebastián García Menéndez, Virna Margarita Martín Giménez, Fatme Al Anouti, Walter Manucha

All Works

Vitamin D (vit D) is widely known for its role in calcium metabolism and its importance for the bone system. However, various studies have revealed a myriad of extra-skeletal functions, including cell differentiation and proliferation, antibacterial, antioxidant, immunomodulatory, and anti-inflammatory properties in various cells and tissues. Vit D mediates its function via regulation of gene expression by binding to its receptor (VDR) which is expressed in almost all cells within the body. This review summarizes the pleiotropic effects of vit D, emphasizing its anti-inflammatory effect on different organ systems. It also provides a comprehensive overview of the genetic and epigenetic …

Metagenomic Analysis Of The Outdoor Dust Microbiomes: A Case Study From Abu Dhabi, Uae, Lina Maloukh, Yousef Nazzal, Alagappan Kumarappan, Fares Howari, Lakshmi Kesari Ambika, Rihab Yahmadi, Manish Sharma, Jibran Iqbal, Ahmed A. Al-Taani, Imen Ben Salem, Cijo M. Xavier, Muhamad Naseem

All Works

Outdoor dust covers a shattered range of microbial agents from land over transportation, human microbial flora, which includes pathogen and commensals, and airborne from the environment. Dust aerosols are rich in bacterial communities that have a major impact on human health and living environments. In this study, outdoor samples from roadside barricades, safety walls, and fences (18 samples) were collected from Abu Dhabi, UAE and bacterial diversity was assessed through a 16S rRNA amplicon next generation sequencing approach. Clean data from HiSeq produced 1,099,892 total reads pairs for 18 samples. For all samples, taxonomic classifications were assigned to the OTUs …

Carla+: An Evolution Of The Carla Simulator For Complex Environment Using A Probabilistic Graphical Model, Sumbal Malik, Manzoor Ahmed Khan, Aadam, Hesham El-Sayed, Farkhund Iqbal, Jalal Khan, Obaid Ullah

All Works

In an urban and uncontrolled environment, the presence of mixed traffic of autonomous vehicles, classical vehicles, vulnerable road users, e.g., pedestrians, and unprecedented dynamic events makes it challenging for the classical autonomous vehicle to navigate the traffic safely. Therefore, the realization of collaborative autonomous driving has the potential to improve road safety and traffic efficiency. However, an obvious challenge in this regard is how to define, model, and simulate the environment that captures the dynamics of a complex and urban environment. Therefore, in this research, we first define the dynamics of the envisioned environment, where we capture the dynamics relevant …

Allelic Discrimination Of Vitamin D Receptor Polymorphisms And Risk Of Type 2 Diabetes Mellitus: A Case-Controlled Study, Amal Ahmed Mohammed, Dina M.Abo El-Matty, Rola Abdel-Azeem, Khaled Raafat, Mona A. Hussein, Amira R. El-Ansary, Wael Hafez, Hatem Ahmed Hassan, Nourelhuda Ahmed Nassar, Nora Mahmoud Selim, Doaa Ghaith, Amal A.El Kholy, Soha M. Abd El Salam, Fatme Al Anouti, Alaa S. Wahba

All Works

(1) Background: Type 2 diabetes mellitus (T2DM) is one of the rapidly growing healthcare problems, and several vitamin D receptor (VDR) polymorphisms seem to modulate the risk of T2DM. Our research was designed to investigate the allelic discrimination of VDR polymorphisms and T2DM occurrence risk. (2) Methods: This case-control research included 156 patients with T2DM and 145 healthy control subjects. Most of the study population were males 56.6% vs. 62.8% in the case and control groups, respectively. Genotyping for VDR single nucleotide polymorphisms (SNPs), rs228570 (Fok1), rs7975232 (Apa1), and rs1544410 (Bsm1) was compared between both groups. (3) Results: There was …

Intelligent Health Care And Diseases Management System: Multi-Day-Ahead Predictions Of Covid-19, Ahed Abugabah, Farah Shahid

All Works

The rapidly growing number of COVID-19 infected and death cases has had a catastrophic worldwide impact. As a case study, the total number of death cases in Algeria is over two thousand people (increased with time), which drives us to search its possible trend for early warning and control. In this paper, the proposed model for making a time-series forecast for daily and total infected cases, death cases, and recovered cases for the countrywide Algeria COVID-19 dataset is a two-layer dropout gated recurrent unit (TDGRU). Four performance parameters were used to assess the model’s performance: mean absolute error (MAE), root …

Design And Analysis Of Circular Polarized Two-Port Mimo Antennas With Various Antenna Element Orientations, Fatma Taher, Hussam Al Hamadi, Mohammed S. Alzaidi, Hesham Alhumyani, Dalia H. Elkamchouchi, Yasser H. Elkamshoushy, Mohammad T. Haweel, Mohamed Fathy Abo Sree, Sara Yehia Abdel Fatah

All Works

This article presents the circularly polarized antenna operating over 28 GHz mm-wave applications. The suggested antenna has compact size, simple geometry, wideband, high gain, and offers circular polarization. Afterward, two-port MIMO antenna are designed to get Left Hand Circular Polarization (LHCP) and Right-Hand Circular Polarization (RHCP). Four different cases are adopted to construct two-port MIMO antenna of suggested antenna. In case 1, both of the elements are placed parallel to each other; in the second case, the element is parallel but the radiating patch of second antenna element are rotated by 180°. In the third case, the second antenna element …

Continuing Legal Education In Germany – Digitalization, Dirk Hartung

Research Collection Yong Pung How School Of Law

Let me begin with a brief introduction to my home institution: Bucerius Law School in Hamburg, Germany. The school is named after Dr. Gerd Bucerius, a famous German publisher, politician and lawyer by training. Bucerius Law School, founded in 2000, is a private institution, which is atypical in Germany, where most of higher education institutions are publicly funded. In addition, Bucerius is rather small. We educate about 120 people per year and a total of 400-500 LL.B. students on our campus at any point in time. In addition, we offer a Master of Law and Business Program with 30 to …

Wallaby Pilot Survey: H I Gas Kinematics Of Galaxy Pairs In Cluster Environment, Shin-Jeong Kim, Se-Heon Oh, Jing Wang, Lister Staveley-Smith, Bärbel S. Koribalski, Minsu Kim, Hye-Jin Park, Shinna Kim, Kristine Spekkens, Juan P. Madrid

Physics & Astronomy Faculty Publications

We examine the H I gas kinematics of galaxy pairs in two clusters and a group using Australian Square Kilometre Array Pathfinder (ASKAP) WALLABY pilot survey observations. We compare the H I properties of galaxy pair candidates in the Hydra I and Norma clusters, and the NGC 4636 group, with those of non-paired control galaxies selected in the same fields. We perform H I profile decomposition of the sample galaxies using a tool, BAYGAUD, which allows us to deblend a line-of-sight velocity profile with an optimal number of Gaussian components. We construct H I superprofiles of the sample galaxies via …

Oral Ibrexafungerp For Vulvovaginal Candidiasis Treatment: An Analysis Of Vanish 303 And Vanish 306, Oluwatosin Goje, Ryan Sobel, Paul Nyirjesy, Steven R Goldstein, Mark Spitzer, Brooke Faught, Shelagh Larson, Thomas King, Nkechi E Azie, David Angulo, Jack D Sobel

Department of Obstetrics and Gynecology Faculty Papers

Background: Ibrexafungerp is a novel antifungal treatment for acute vulvovaginal candidiasis (VVC). Using pooled data from two phase three studies (VANISH 303 and 306) in the treatment of acute VVC, this analysis sought to determine the effectiveness of ibrexafungerp in various patient subgroups that may impact outcomes. Materials and Methods: Data from VANISH 303 (NCT03734991) and VANISH 306 (NCT03987620) evaluating ibrexafungerp 300 mg twice daily (BID) for 1 day versus placebo, were pooled and analyzed to determine clinical cure rate, clinical improvement, and mycological cure at the test-of-cure visit (day 11 ± 3) and symptom resolution …

Practical Pointers: A Five-Star Church, S. Joseph Kidder

Faculty Publications

No abstract provided.

How To Read Ellen White's Writings Today, Denis Kaiser

Faculty Publications

No abstract provided.

Rosetta Rose Holloway

African American Funeral Programs

Rosetta_Rosa_Holloway.pdf - Funeral program for Rosetta Holloway

4-H Volunteer Conference Workshop Descriptions, Extension

UNH Cooperative Extension

No abstract provided.

Dairy Knowledge Bowl Packet, Extension

UNH Cooperative Extension

No abstract provided.

Agritourism Development: Neighborhood And Community Considerations, Jada Lindblom Ph.D.

UNH Cooperative Extension

An increasing number of farms in NH and beyond are incorporating agritourism activities and/or event hosting into their business models. While these can be valuable strategies in terms of community and economic benefits, neighbor/abutter disputes, zoning regulations, and state laws may pose challenges. These presentation slides offer tips from town planners and agritourism operators for navigating potential roadblocks.

Understanding And Advancing The Preservation Trades, Jada Lindblom Ph.D., Scott Slattery, Molly Donovan

UNH Cooperative Extension

Showing a collective interest in the preservation and restoration trades workforce, four statewide preservation nonprofits (representing NY, VT, NH, and ME) joined forces in 2021 to create the Northeast Regional Initiative for the Preservation Trades. The initiative’s aim is to better understand this issue and develop courses of action to foster a more robust and sustainable preservation trades workforce. In 2022, specialists from UNH Cooperative Extension’s Community and Economic Development team partnered with this initiative to lead a multi-methods research project consisting of a survey, interviews, and focus groups with trades professionals, preservation specialists, workforce development professionals, educators, and other …

Understanding And Advancing The Preservation Trades (2-Page View)), Jada Lindblom Ph.D., Scott Slattery, Molly Donovan

UNH Cooperative Extension

Showing a collective interest in the preservation and restoration trades workforce, four statewide preservation nonprofits (representing NY, VT, NH, and ME) joined forces in 2021 to create the Northeast Regional Initiative for the Preservation Trades. The initiative’s aim is to better understand this issue and develop courses of action to foster a more robust and sustainable preservation trades workforce. In 2022, specialists from UNH Cooperative Extension’s Community and Economic Development team partnered with this initiative to lead a multi-methods research project consisting of a survey, interviews, and focus groups with trades professionals, preservation specialists, workforce development professionals, educators, and other …

Prediction Of Wilms’ Tumor Susceptibility To Preoperative Chemotherapy Using A Novel Computer-Aided Prediction System, Israa Sharaby, Ahmed Alksas, Ahmed Nashat, Hossam Magdy Balaha, Mohamed Shehata, Mallorie Gayhart, Ali Mahmoud, Mohammed Ghazal, Ashraf Khalil, Rasha T. Abouelkheir, Ahmed Elmahdy, Ahmed Abdelhalim, Ahmed Mosbah, Ayman El-Baz

All Works

Wilms’ tumor, the most prevalent renal tumor in children, is known for its aggressive prognosis and recurrence. Treatment of Wilms’ tumor is multimodal, including surgery, chemotherapy, and occasionally, radiation therapy. Preoperative chemotherapy is used routinely in European studies and in select indications in North American trials. The objective of this study was to build a novel computer-aided prediction system for preoperative chemotherapy response in Wilms’ tumors. A total of 63 patients (age range: 6 months–14 years) were included in this study, after receiving their guardians’ informed consent. We incorporated contrast-enhanced computed tomography imaging to extract the texture, shape, and functionality-based …

Exploring Teacher Education For Sustainable Development In The Uae, Sandra Baroudi

All Works

New ways of modernizing professional development programs (hereafter PDs) focus on the acquisition of new teaching methods and techniques through hands-on opportunities provided to teachers, thereby enabling them to practice and reflect on the knowledge gained. Moreover, the new vision of reform and sustainability in education emphasizes the development of sustainable PDs that resist disruptive factors, increase teachers’ commitment, and ensure more sustainable development across children’s lifespans. This study explores the impact of a piloted sustainable PD on the development of 16 teachers and head teachers’ attitudes about assessment practices, professional growth, and leadership skills. Qualitative data collected in the …

The Impact Of Objectively Recorded Smartphone Usage And Emotional Intelligence On Problematic Internet Usage, Sameha Alshakhsi, Khansa Chemnad, Mohamed Basel Almourad, Majid Altuwairiqi, John Mcalaney, Raian Ali

All Works

This study examined the effects of gender, age, objective smartphone usage data, and Emotional Intelligence (EI) on Problematic Internet Use (PIU) and its components (obsession, neglect, and control disorder). The study relied on objective data of smartphone usage as a representative of technology use collected by a monitoring application of smartphone usage. PIU and EI were measured through the Problematic Internet Usage Questionnaire short form (PIUQ-SF-6) and Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF), respectively. The current cross-sectional study was carried out with 268 participants (Female: 61.6%, ages from 15 to 64) from ten different countries. The analysis was performed using …

Engineering A Microbiosphere To Clean Up The Ocean – Inspiration From The Plastisphere, Khulood A. Alnahdi, Laila W. Alali, Mezna K. Suwaidan, M. Kalim Akhtar

All Works

Plastic is a ubiquitous material that has become an essential part of our lives. More than one hundred million tons of plastic has accumulated in the world’s oceans as a result of poor waste management. This plastic waste gradually fragments into smaller pieces known as microplastics and nanoplastics. These small plastic particles can cause significant damage to marine ecosystems, and negatively impact human health. According to a recent review of international patents, the majority of ocean-cleaning inventions are limited to microplastics larger than 20 μm. Furthermore, such technologies are ineffective for nanoplastics, which measure less than 1000 nm, or even …

Towards Machine Learning-Based Fpga Backend Flow: Challenges And Opportunities, Imran Taj, Umer Farooq

All Works

Field-Programmable Gate Array (FPGA) is at the core of System on Chip (SoC) design across various Industry 5.0 digital systems—healthcare devices, farming equipment, autonomous vehicles and aerospace gear to name a few. Given that pre-silicon verification using Computer Aided Design (CAD) accounts for about 70% of the time and money spent on the design of modern digital systems, this paper summarizes the machine learning (ML)-oriented efforts in different FPGA CAD design steps. With the recent breakthrough of machine learning, FPGA CAD tasks—high-level synthesis (HLS), logic synthesis, placement and routing—are seeing a renewed interest in their respective decision-making steps. We focus …

Augmenting Ccam Infrastructure For Creating Smart Roads And Enabling Autonomous Driving, M. Jalal Khan, Manzoor Ahmed Khan, Obaid Ullah, Sumbal Malik, Farkhund Iqbal, Hesham El-Sayed, Sherzod Turaev

All Works

Autonomous vehicles and smart roads are not new concepts and the undergoing development to empower the vehicles for higher levels of automation has achieved initial milestones. However, the transportation industry and relevant research communities still require making considerable efforts to create smart and intelligent roads for autonomous driving. To achieve the results of such efforts, the CCAM infrastructure is a game changer and plays a key role in achieving higher levels of autonomous driving. In this paper, we present a smart infrastructure and autonomous driving capabilities enhanced by CCAM infrastructure. Meaning thereby, we lay down the technical requirements of the …