Digital Commons Network^™

Selectively Modified Lactose And N-Acetyllactosamine Analogs At Three Key Positions To Afford Effective Galectin-3 Ligands †, Shuay Abdullayev, Priyanka Dipak Kadav, Purnima Bandyopadhyay, Francisco Javier Medrano, Gabriel A. Rabinovich, Tarun K. Dam, Antonio Romero, René Roy

Michigan Tech Publications, Part 1

Galectins constitute a family of galactose-binding lectins overly expressed in the tumor microenvironment as well as in innate and adaptive immune cells, in inflammatory diseases. Lactose ((β-D-galactopyranosyl)-(1→4)-β-D-glucopyranose, Lac) and N-Acetyllactosamine (2-acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, LacNAc) have been widely exploited as ligands for a wide range of galectins, sometimes with modest selectivity. Even though several chemical modifications at single positions of the sugar rings have been applied to these ligands, very few examples combined the simultaneous modifications at key positions known to increase both affinity and selectivity. We report herein combined modifications at the anomeric position, C-2, and O-3′ of each of the two …

A Catalog Of The Highest-Energy Cosmic Rays Recorded During Phase I Of Operation Of The Pierre Auger Observatory, A. Abdul Halim, P. Abreu, M. Aglietta, I. Allekotte, P. Allison, K. Almeida Cheminant, J. Chirinos, B. Fick, D. Nitz, I. Norwood, A. Puyleart, Et Al.

Michigan Tech Publications, Part 1

A catalog containing details of the highest-energy cosmic rays recorded through the detection of extensive air showers at the Pierre Auger Observatory is presented with the aim of opening the data to detailed examination. Descriptions of the 100 showers created by the highest-energy particles recorded between 2004 January 1 and 2020 December 31 are given for cosmic rays that have energies in the range 78-166 EeV. Details are also given on a further nine very energetic events that have been used in the calibration procedure adopted to determine the energy of each primary. A sky plot of the arrival directions …

Utilization Of Mechanically Recycled Carbon Fibers In Vinyl Ester Composites, Khaled Alharmoodi, Amir Hussain Idrisi, Abdel Hamid Ismail Mourad, Basim Abu-Jdayil

Michigan Tech Publications, Part 1

As we enter the twenty-first century, the aviation sector is expected to thrive as flying becomes the primary mode of transportation between states or nations. With such a demand, there is a corresponding need to manufacture aircraft components. The study focused on recycling carbon fiber composites received from the STRATA company, which were cut-off/waste material generated during the manufacture of airplane components. The cut-offs were then reduced to powder form using a standard face milling machine in three sizes (90, 150, and 250 µm). After, the powder was utilized to fabricate vinyl ester composites with four weight percentages (10%, 20%, …

The Genetic Mechanisms Underlying The Concerted Expression Of The Yellow And Tan Genes In Complex Patterns On The Abdomen And Wings Of Drosophila Guttifera, Komal K.B. Raja, Evan A. Bachman, Catrina E. Fernholz, David S. Trine, Rebecca E. Hobmeier, Nathaniel J. Maki, Timothy J. Massoglia, Thomas Werner

Michigan Tech Publications, Part 1

How complex morphological patterns form is an intriguing question in developmental biology. However, the mechanisms that generate complex patterns remain largely unknown. Here, we sought to identify the genetic mechanisms that regulate the tan (t) gene in a multi-spotted pigmentation pattern on the abdomen and wings of Drosophila guttifera. Previously, we showed that yellow (y) gene expression completely prefigures the abdominal and wing pigment patterns of this species. In the current study, we demonstrate that the t gene is co-expressed with the y gene in nearly identical patterns, both transcripts foreshadowing the adult abdominal and wing melanin spot patterns. We …

Noise2clean: Cross-Device Side-Channel Traces Denoising With Unsupervised Deep Learning, Honggang Yu, Mei Wang, Xiyu Song, Haoqi Shan, Hongbing Qiu, Junyi Wang, Kaichen Yang

Michigan Tech Publications, Part 1

Deep learning (DL)-based side-channel analysis (SCA) has posed a severe challenge to the security and privacy of embedded devices. During its execution, an attacker exploits physical SCA leakages collected from profiling devices to create a DL model for recovering secret information from victim devices. Despite this success, recent works have demonstrated that certain countermeasures, such as random delay interrupts or clock jitters, would make these attacks more complex and less practical in real-world scenarios. To address this challenge, we present a novel denoising scheme that exploits the U-Net model to pre-process SCA traces for “noises” (i.e., countermeasures) removal. Specifically, we …

The Phangs-Jwst Treasury Survey: Star Formation, Feedback, And Dust Physics At High Angular Resolution In Nearby Galaxies, Janice C. Lee, Karin M. Sandstrom, Adam K. Leroy, David A. Thilker, Eva Schinnerer, Erik Rosolowsky, Judy Schmidt, Et Al.

Michigan Tech Publications, Part 1

The PHANGS collaboration has been building a reference data set for the multiscale, multiphase study of star formation and the interstellar medium (ISM) in nearby galaxies. With the successful launch and commissioning of JWST, we can now obtain high-resolution infrared imaging to probe the youngest stellar populations and dust emission on the scales of star clusters and molecular clouds (∼5-50 pc). In Cycle 1, PHANGS is conducting an eight-band imaging survey from 2 to 21 μm of 19 nearby spiral galaxies. Optical integral field spectroscopy, CO(2-1) mapping, and UV-optical imaging for all 19 galaxies have been obtained through large programs …

Dsrc Versus Lte-V2x: Empirical Performance Analysis Of Direct Vehicular Communication Technologies, Ehsan Moradi-Pari, Danyang Tian, Mojtaba Bahramgiri, Samer Rajab, Sue Bai

Michigan Tech Publications, Part 1

Vehicle-to-Vehicle (V2V) communication systems have an eminence potential to improve road safety and optimize traffic flow by broadcasting Basic Safety Messages (BSMs). Dedicated Short-Range Communication (DSRC) and LTE Vehicle-to-Everything (V2X) are two candidate technologies to enable V2V communication. DSRC relies on the IEEE 802.11p standard for its PHY and MAC layer while LTE-V2X is based on 3GPP’s Release 14 and operates in a distributed manner in the absence of cellular infrastructure. There has been considerable debate over the relative advantages and disadvantages of DSRC and LTE-V2X, aiming to answer the fundamental question of which technology is most effective in real-world …

The Effects Of Robot Voices And Appearances On Users' Emotion Recognition And Subjective Perception, Sangjin Ko, Jaclyn A. Barnes, Jiayuan Dong, Chung Hyuk Park, Ayanna Howard, Myounghoon Jeon

Michigan Tech Publications, Part 1

As the influence of social robots in people's daily lives grows, research on understanding people's perception of robots including sociability, trust, acceptance, and preference becomes more pervasive. Research has considered visual, vocal, or tactile cues to express robots' emotions, whereas little research has provided a holistic view in examining the interactions among different factors influencing emotion perception. We investigated multiple facets of user perception on robots during a conversational task by varying the robots' voice types, appearances, and emotions. In our experiment, 20 participants interacted with two robots having four different voice types. While participants were reading fairy tales to …

Review Of Preaching To People In Pain: How Suffering Can Shape Your Sermons And Connect With Your Congregations By Matthew D. Kim, Grand Rapids, Mi: Baker Academic, 2021., Rodney Palmer

Faculty Publications

No abstract provided.

Da Principio: Ancorando L'Etica All'evento Della Creazione, Davide Sciarabba

Faculty Publications

No abstract provided.

Calling An Ambulance For Non-Emergency Medical Situations: Results Of A Cross-Sectional Online Survey From An Australian Nationally Representative Sample, Brennen Mills, Michella Hill, Alecka Miles, Erin Smith, Eben Afrifa-Yamoah, David Reid, Shane Rogers, Moira Sim

Research outputs 2022 to 2026

Objective

To investigate the Australian general public's perception of appropriate medical scenarios that warrants a call to an emergency ambulance.

Methods

An online survey asked participants to identify the likely medical treatment pathway they would take for 17 hypothetical medical scenarios. The number and type of non-emergency scenarios (n = 8) participants incorrectly suggested were appropriate to place a call for an emergency ambulance were calculated. Participants included Australian residents (aged >18 years) who had never worked as an Australian registered medical doctor, nurse or paramedic.

Results

From a sample of 5264 participants, 40% suggested calling an emergency ambulance …

Overexpression Of Both Human Sodium Iodide Symporter (Nis) And Brg1-Bromodomain Synergistically Enhances Radioiodine Sensitivity By Stabilizing P53 Through Npm1 Expression, J Na, C-H Lee, J-K Chung, H Youn

Peninsula Medical School

Improved therapeutic strategies are required to minimize side effects associated with radioiodine gene therapy to avoid unnecessary damage to normal cells and radiation-induced secondary malignancies. We previously reported that codon-optimized sodium iodide symporter (oNIS) enhances absorption of I-131 and that the brahma-associated gene 1 bromodomain (BRG1-BRD) causes inefficient DNA damage repair after high-energy X-ray therapy. To increase the therapeutic effect without applying excessive radiation, we considered the combination of oNIS and BRG1-BRD as gene therapy for the most effective radioiodine treatment. The antitumor effect of I-131 with oNIS or oNIS+BRD expression was examined by tumor xenograft models along with functional …

Automated In Vivo High-Resolution Imaging To Detect Human Papillomavirus-Associated Anal Precancer In Persons Living With Hiv, David Brenes, Alex Kortum, Jennifer Carns, Tinaye Mutetwa, Richard Schwarz, Yuxin Liu, Keith Sigel, Rebecca Richards-Kortum, Sharmila Anandasabapathy, Michael Gaisa, Elizabeth Chiao

Faculty, Staff and Students Publications

INTRODUCTION: In the United States, the effectiveness of anal cancer screening programs has been limited by a lack of trained professionals proficient in high-resolution anoscopy (HRA) and a high patient lost-to-follow-up rate between diagnosis and treatment. Simplifying anal intraepithelial neoplasia grade 2 or more severe (AIN 2+) detection could radically improve the access and efficiency of anal cancer prevention. Novel optical imaging providing point-of-care diagnoses could substantially improve existing HRA and histology-based diagnosis. This work aims to demonstrate the potential of high-resolution microendoscopy (HRME) coupled with a novel machine learning algorithm for the automated, in vivo diagnosis of anal precancer. …

Association Of Lifestyle Behaviors With Non-Alcoholic Fatty Liver Disease And Advanced Fibrosis Detected By Transient Elastography Among Hispanic/Latinos Adults In The Us, Natalia I Heredia, Xiaotao Zhang, Maya Balakrishnan, Jessica P Hwang, Aaron P Thrift

Faculty, Staff and Students Publications

OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent liver disease, with the highest prevalence observed in the U.S. among Hispanic/Latino adults. While physical activity and dietary behaviors have established protective associations with NAFLD and its severity, these associations have not been well-characterized in Hispanic/Latino adults. The purpose of this study was to assess the association of lifestyle behaviors with NAFLD and advanced fibrosis in US Hispanic/Latino adults.

DESIGN: We selected all Hispanic/Latino adults from the 2017-2018 National Health and Nutrition Examination Survey (NHANES). NAFLD was defined as CAP ≥285 dB/m, and advanced fibrosis as liver stiffness measurements ≥8.6 …

Woman-Centred Ethics: A Feminist Participatory Action Research [Journal Article], Kate Buchanan, Sadie Geraghty, Lisa Whitehead, Elizabeth Newnham

Research outputs 2022 to 2026

Introduction: Contemporary ethical issues in the maternity system are nuanced, complex and layered. Medicalisation and the reported rise in incidence of mistreatment and birth trauma, has been described as unethical. Some authors suggest bioethical principles are limited in terms of guiding everyday care of pregnancy and birth. There is currently no known published research which explores what birthing people say is ethical. Aims: This study sought to explore women's experience of maternity care from an ethical perspective. Method: A Feminist Participatory Action Research (FPAR) was conducted over three years, in two phases. A Community Action Research Group (CARG) was formed …

Proposal For And Validation Of Novel Risk-Based Process To Reduce The Risk Of Construction Site Fatalities (Major Accident Prevention (Map) Program), Roberta Selleck, Marcus Cattani, Maureen Hassall

Research outputs 2022 to 2026

Despite developments in the prevention of fatalities in the construction industry, fatalities resulting from well-known hazards continue at an unacceptable rate. Construction fatality prevention literature describes risk management techniques to provide ‘early warning’ of potential events. In dynamic construction project environments, these ‘early warnings’ are missed resulting in serious and fatal events. Critical Control Risk Management (CCRM) provides an alternative strategy to prevent fatal events in the construction industry. However, no research exists that explores the application of CCRM to actual construction projects. This study aims to design, develop, and validate a construction fatality prevention program using CCRM principles through …

Motor Cortical Excitability And Pre-Supplementary Motor Area Neurochemistry In Healthy Adults With Substantia Nigra Hyperechogenicity, Gabrielle Todd, Caroline D. Rae, Janet L. Taylor, Nigel C. Rogasch, Jane E. Butler, Michael Hayes, Robert A. Wilcox, Simon C. Gandevia, Karl Aoun, Adrian Esterman, Simon J. G. Lewis, Julie M. Hall, Elie Matar, Jana Godau, Daniela Berg, Christian Plewnia, Anna-Katharina Von Thaler, Clarence Chiang, Kay L. Double

Research outputs 2022 to 2026

Substantia nigra (SN) hyperechogenicity, viewed with transcranial ultrasound, is a risk marker for Parkinson's disease. We hypothesized that SN hyperechogenicity in healthy adults aged 50 – 70 years is associated with reduced short-interval intracortical inhibition in primary motor cortex, and that the reduced intracortical inhibition is associated with neurochemical markers of activity in the pre-supplementary motor area (pre-SMA). Short-interval intracortical inhibition and intracortical facilitation in primary motor cortex was assessed with paired-pulse transcranial magnetic stimulation in 23 healthy adults with normal (n = 14; 61 ± 7 yrs) or abnormally enlarged (hyperechogenic; n = 9; 60 ± 6 yrs) area …

Bzip Transcription Factors Repress The Expression Of Wheat (Triticum Aestivum L.) High Molecular Weight Glutenin Subunit Genes In Vegetative Tissues, Csaba Éva, Blanka Moncsek, Kitti Szőke-Pázsi, Viola Kunos, Klára Mészáros, Szabolcs Makai, László Sági, Angéla Juhász

Research outputs 2022 to 2026

High molecular weight glutenin subunits (HMW GS) represent an important fraction of endosperm-specific seed-storage proteins that provide elasticity to bread dough. Previously, the second cis-regulatory module (CRM2) was found to be one of the most conserved part of HMW GS promoters, which indicated its pre-eminent role in their gene regulation. Here, we observed that deletion of CRM2 from the promoters of the Bx7 and By8 HMW GS genes increased the leakage of their transient expression in wheat leaf tissue. The effect of a VP1, an Myb and an antisense bZIP transcription factor (TF)-binding site, potentially involved in endosperm-specific regulation within …

Effects Of Supply Chain Transparency, Alignment, Adaptability, And Agility On Blockchain Adoption In Supply Chain Among Smes, Mohammad Iranmanesh, Parisa Maroufkhani, Shahla Asadi, Morteza Ghobakhloo, Yogesh K. Dwivedi, Ming-Lang Tseng

Research outputs 2022 to 2026

This study aims to investigate the extent to which the contributions of blockchain technology to supply chain parameters influence blockchain adoption among SMEs. Drawing on contingency theory, the study investigates the moderating effect of market turbulence. The data were collected from 204 SMEs in Malaysia's manufacturing sector and analysed using the partial least squares technique. The results showed that the intention of SMEs’ managers to adopt blockchain is influenced by the contributions of blockchain to supply chain transparency and agility. Supply chain transparency, alignment, adaptability, and agility are interrelated. Market turbulence moderates positively the association between agility and intention to …

Models Of School Breakfast Program Implementation In Western Australia And The Implications For Supporting Disadvantaged Students, Susan M. Hill, Matthew F. Byrne, Elizabeth Wenden, Amanda Devine, Margaret Miller, Henrietta Quinlan, Donna Cross, Judy Eastham, Miranda Chester

Research outputs 2022 to 2026

A substantial body of literature points to the educational and social benefits of school breakfast programs. Most high-income countries provide free or subsidized school breakfasts to support disadvantaged children. Australia does not have a nationally-funded school meal program. Instead, charitable organizations offer school breakfast programs on a voluntary basis, often with funding support from state/territory governments. Decisions about participating in a school breakfast program (SBP), which students to support, and the degree of integration with other strategies to support disadvantaged students are made at the school level. This large-scale, multi-year study examined models of SBP implementation in Western Australian (WA) …

A Computational Offloading Optimization Scheme Based On Deep Reinforcement Learning In Perceptual Network, Yongli Xing, Tao Ye, Sami Ullah, Muhammad Waqas, Hisham Alasmary, Zihui Liu

Research outputs 2022 to 2026

Currently, the deep integration of the Internet of Things (IoT) and edge computing has improved the computing capability of the IoT perception layer. Existing offloading techniques for edge computing suffer from the single problem of solidifying offloading policies. Based on this, combined with the characteristics of deep reinforcement learning, this paper investigates a computation offloading optimization scheme for the perception layer. The algorithm can adaptively adjust the computational task offloading policy of IoT terminals according to the network changes in the perception layer. Experiments show that the algorithm effectively improves the operational efficiency of the IoT perceptual layer and reduces …

Citation Impact And Reach Of The Ioc Sport And Exercise Medicine Consensus Statements, Lauren V. Fortington, Rebecca N. Handcock, Wayne Derman, Carolyn A. Emery, Kati Pasanen, Martin Schwellnus, Evert Verhagen, Caroline F. Finch

Research outputs 2022 to 2026

Background: Research evidence is commonly compiled into expert-agreed consensus statements or guidelines, with an increasing trend towards their publication in peer-reviewed journals. Prominent among these has been the publication of several International Olympic Committee (IOC) tatements to help inform sport and exercise medicine (SEM) practice. This study aimed to assess the citation impact and reach of the IOC statements published between 2003 and 2020. Method: Bibliometric analysis focused on identifying core publications (original statement and linked publications) and quantifying their academic citations (number and Field-Weighted Citation Impact (FWCI)) in journal articles up to February 2022. The analysis includes descriptive data …

Clinical Epigenomic Explanation Of The Epidemiology Of Cannabinoid Genotoxicity Manifesting As Transgenerational Teratogenesis, Cancerogenesis And Aging Acceleration, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

As global interest in the therapeutic potential of cannabis and its’ derivatives for the management of selected diseases increases, it is increasingly imperative that the toxic profile of cannabinoids be thoroughly understood in order to correctly assess the balance between the therapeutic risks and benefits. Modern studies across a number of jurisdictions, including Canada, Australia, the US and Europe have confirmed that some of the most worrying and severe historical reports of both congenital anomalies and cancer induction following cannabis exposure actually underestimate the multisystem thousand megabase-scale transgenerational genetic damage. These findings from teratogenic and carcinogenic literature are supported by …

Corticospinal And Intracortical Responses From Both Motor Cortices Following Unilateral Concentric Versus Eccentric Contractions, Onno Van Der Groen, Christopher Latella, Kazunori Nosaka, Dylan Edwards, Wei Peng Teo, Janet L. Taylor

Research outputs 2022 to 2026

Cross-education is the phenomenon where training of one limb can cause neuromuscular adaptations in the opposite untrained limb. This effect has been reported to be greater after eccentric (ECC) than concentric (CON) strength training; however, the underpinning neurophysiological mechanisms remain unclear. Thus, we compared responses to transcranial magnetic stimulation (TMS) in both motor cortices following single sessions of unilateral ECC and CON exercise of the elbow flexors. Fourteen healthy adults performed three sets of 10 ECC and CON right elbow flexor contractions at 75 % of respective maximum on separate days. Elbow flexor maximal voluntary isometric contraction (MVIC) torques were …

Editorial: Untangle The Broad Connections And Tight Interactions Between Human Microbiota And Complex Diseases Through Data-Driven Approaches, Liang Wang, Zuo-Bin Zhu, Li Zhang, Jian Li, Qi Zhao

Research outputs 2022 to 2026

It is well-known that microorganisms are ubiquitous in the environment and occupy almost all habitats in animals and humans (Finlay and Clarke, 1999; Rosenberg, 2021). Traditionally, microorganisms are studied as individuals grown in isolation under artificial conditions; however, with the development of experimental techniques and computational methods, microbes are now frequently considered as a functional group in a particular niche and studied at the community level in order to best mimicking the real-world situations (American Academy of Microbiology, 2004). During the study of microbial communities, two terms are commonly used, that is, microbiota and microbiome.

Effect Of Deferoxamine On Post-Transfusion Iron, Inflammation, And In Vitro Microbial Growth In A Canine Hemorrhagic Shock Model: A Randomized Controlled Blinded Pilot Study, Melissa A. Claus, Lisa Smart, Anthea L. Raisis, Claire R. Sharp, Sam Abraham, Joel P. A. Gummer, Martin K. Mead, Damian L. Bradley, Rachel Van Swelm, Erwin T. G. Wiegerinck, Edward Litton

Research outputs 2022 to 2026

Red blood cell (RBC) transfusion is associated with recipient inflammation and infection, which may be triggered by excessive circulating iron. Iron chelation following transfusion may reduce these risks. The aim of this study was to evaluate the effect of deferoxamine on circulating iron and inflammation biomarkers over time and in vitro growth of Escherichia coli (E. coli) following RBC transfusion in dogs with atraumatic hemorrhage. Anesthetized dogs were subject to atraumatic hemorrhage and transfusion of RBCs, then randomized to receive either deferoxamine or saline placebo of equivalent volume (n = 10 per group) in a blinded fashion. Blood was sampled …

Impact Of The Skill Shortage On The Construction Supply Chain Performance In Australia, Ming Juan Ding, Ferry Jie, Sommala Sisombat, Bala S. Bandlamudi

Research outputs 2022 to 2026

The purpose of this paper is to investigate how the skill shortage impacts the performance of the construction supply chain in Australia. The study has adopted a quantitative research method. The quantitative data were collected by conducting a survey of employees who work in construction companies in Australia. A regression analysis was used to analyze the data from 113 respondents. The findings of the study reveal that the construction sector in Australia has high labour costs, but workers are still thinking they are not getting paid enough and cannot invest more in themselves to improve their skills. There is a …

Prediction Models Of Shielding Effectiveness Of Carbon Fibre Reinforced Cement-Based Composites Against Electromagnetic Interference, Shilpa Narayanan, Yifan Zhang, Farhad Aslani

Research outputs 2022 to 2026

With the rapid development of communication technology as well as a rapid rise in the usage of electronic devices, a growth of concerns over unintentional electromagnetic interference emitted by these devices has been witnessed. Pioneer researchers have deeply studied the relationship between the shielding effectiveness and a few mixed design parameters for cementitious composites incoporating carbon fibres by conducting physical experiments. This paper, therefore, aims to develop and propose a series of prediction models for the shielding effectiveness of cementitious composites involving carbon fibres using frequency and mixed design parameters, such as the water-to-cement ratio, fibre content, sand-to-cement ratio and …

Site Selection Of Combined Offshore Wind And Wave Energy Farms: A Systematic Review, Shabnam Hosseinzadeh, Amir Etemad-Shahidi, Rodney A. Stewart

Research outputs 2022 to 2026

Growing energy demand worldwide and onshore limitations have increased interest in offshore renewable energy exploitation. A combination of offshore renewable energy resources such as wind and wave energy can produce stable power output at a lower cost compared to a single energy source. Consequently, identifying the best locations for constructing combined offshore renewable energy farms is crucial. This paper investigates the technical, economic, social, and environmental aspects of Combined Offshore Wind and Wave Energy Farm (COWWEF) site selection. Past literature was evaluated using a systematic review method to synthesize, criticize, and categorize study regions, dataset characteristics, constraints, evaluation criteria, and …

Using Nanomaterials As Excellent Immobilisation Layer For Biosensor Design, Azeez Olayiwola Idris, Seyi Philemon Akanji, Benjamin O. Orimolade, Foluke Omobola Grace Olorundare, Shohreh Azizi, Bhekie Mamba, Malik Maaza

Research outputs 2022 to 2026

The endless development in nanotechnology has introduced new vitality in device fabrication including biosensor design for biomedical applications. With outstanding features like suitable biocompatibility, good electrical and thermal conductivity, wide surface area and catalytic activity, nanomaterials have been considered excellent and promising immobilisation candidates for the development of high-impact biosensors after they emerged. Owing to these reasons, the present review deals with the efficient use of nanomaterials as immobilisation candidates for biosensor fabrication. These include the implementation of carbon nanomaterials—graphene and its derivatives, carbon nanotubes, carbon nanoparticles, carbon nanodots—and MXenes, likewise their synergistic impact when merged with metal oxide nanomaterials. …