Digital Commons Network^™

Dietary Influence And Neurodegenerative Disease Risk: Insight From Alzheimer’S And Parkinson’S Disease, Madison Wirt

Honors Projects

As populations age, neurodegenerative diseases (NDD) become significantly more prevalent and impactful on patients and families. Clinical research has suggested a correlation between diet, gut health, neuroinflammation and mitochondrial dysfunction to the onset and development of specific and severe NDDs, especially Alzheimer’s disease (AD) and Parkinson’s disease (PD). This research focuses on the relationship behind the gut-brain axis, micronutrient status and how diet influences the development of both AD and PD. Ten randomized, controlled trials were analyzed from the literature to investigate the impact of these factors on the inflammatory, metabolic and antioxidant processes. The studies focused on the use …

Synthesis And In Vitro Evaluation Of Potential Tuberculosis Antibiotics, Chloe Spradlin

Honors Projects

Tuberculosis (TB) remains a major global health threat. The bacteria causing TB, Mycobacterium tuberculosis, has proven difficult to combat, as drug resistance (MDR-TB) continues to develop within the bacteria. Access to healthcare in developing countries complicates the treatment of TB and MDR-TB. The World Health Organization has declared TB a global health crisis and has called for the development of new therapies. Previously, we used AutoDock Vina software to design novel drugs targeting InhA, an enzyme involved in mycobacterial cell wall synthesis. This project focuses on synthesizing amino diphenyl amides (ADA) and screening them against Mycobacterium. The synthetic pathway enables …

Simulation-Based School Safety Leadership: Practicing Early Warning Sign Recognition And Response, Daniel W. Eadens

Teaching Online Pedagogical Repository

This entry describes the effectiveness of a simulation involving safety.

Faculty List

Missouri Law Review

No abstract provided.

Clinical And Non-Clinical Factors Associated With Early Discharge In Pediatric Non-Trauma Patients Transported By Rotor Wing, Jordon Mitzelfelt, Lisa Pruitt, Amy Papa, Ashley K. Sherman, David Juang, Sarah Brunner, Asdis Finnsdottir Wagner, Jennifer Flint

Posters

Objective: Helicopter emergency medical services (HEMS) are crucial for transporting critically ill children to definitive care, however, rising costs and relative risks of this type of transportation necessitate careful evaluation of potential over-utilization. Current literature primarily focuses on pediatric trauma patients, leaving a significant gap in data regarding non-trauma pediatric HEMS transports and the influence of non-clinical factors such as referral hospital distance, resources, and capabilities on transport decisions. This study aims to address these gaps by examining non-trauma pediatric HEMS patients and identifying associated clinical and non-clinical factors related to early hospital discharge (< 24 hours). Methods: This retrospective, single-center study includes pediatric patients with medical and non-trauma surgical diagnoses transported by HEMS between April 1, 2021 and March 31, 2024. Clinical data were extracted from transport team records and the hospital’s electronic health records. Analyses were performed to identify factors associated with discharge within 24 hours of admission. To identify predictors of early discharge, we analyzed clinical factors including chief complaint, pre-transport vascular access, transport crew interventions (medication administration and procedures), respiratory assistance, and Pediatric Age-Adjusted Shock Index (SIPA) scores. Additionally, we examined the impact of the initial admit unit, and medical support required within the first 24 hours of hospitalization. Non-clinical predictors included the referring hospital’s status (critical access and/or rural designation) and the time of transport. Results: A total of 568 patients were transported by HEMS, of whom 88 (15%) were discharged within 24 hours. Patients in the early discharge group were more likely to present with neurologic chief complaints (40%), whereas those remaining hospitalized beyond 24 hours more frequently presented with respiratory complaints (40%). Normal SIPA scores both prior to and at the conclusion of transport were significantly associated with early discharge (p=0.012 and p=0.011, respectively). Furthermore, patients requiring no medications or respiratory assistance during transport, or no respiratory support within the first 24 hours of admission, were significantly more likely to be discharged early (p< 0.001). Notably, all patients with central access prior to transport remained admitted for more than 24 hours (p=0.004). Regarding non-clinical factors, patients transported from designated rural hospitals were more likely to experience early discharge (p< 0.001). Conclusion: These results characterize the pediatric non-trauma HEMS population and identify key predictors of early hospital discharge. This data is essential for developing standardized dispatch criteria to mitigate over-utilization and ensure high-acuity transport is reserved for the most appropriate patients.

Does Variation In Systemic Steroid Use Impact Outcomes In Preschoolers Hospitalized With Viral Respiratory Tract Infection?, Smit Shah, Kathryn Kyler, Matt Hall, Jessica Markham

Posters

Background: Systemic corticosteroids (SCS) are a cornerstone of treatment for acute asthma exacerbation. However, the role of SCS in preschool-aged children hospitalized with viral respiratory tract infection (vRTI), including viral induced wheezing, remains uncertain. Clinical trials have reported conflicting results about the benefits of SCS in this population. Objectives: To evaluate hospital-level variation in inpatient management of preschool-aged children admitted with vRTI and to compare clinical and utilization outcomes based on hospital-level SCS use. Methods: We conducted a retrospective cohort study of children aged 24-59 months admitted to US children’s hospitals with vRTI from July 2022-July 2024 using the Pediatric …

Reducing Waste And Cost By Utilizing Tap Water For Laceration Irrigation In The Emergency Department: A Quality Improvement Approach, Alison L. Fowler, Rohan Akhouri, Josaih Galdean, Isabella Dunt, Christopher Kaberline, Viktoriya Stoycheva Mha, Rn, Cpn, Sarah Nienhaus, Leslie Hueschen

Posters

Purpose/Objective: Lacerations requiring closure make up 8 million emergency department (ED) visits annually. Irrigating prior to closure with potable tap water decreases cost and waste without increasing rates of infection compared to sterile fluids. Currently, only 3.5% of lacerations closed in our ED are irrigated with tap water. This project aims to increase the percent age of lacerations closed by ED providers irrigated with tap water from 3.5% to 60% by March 2026 in a freestanding pediatric emergency department across two sites (ED 1, ED 2). Design/Methods: A multidisciplinary team (physicians, nurses, QI consultant, parent advisors) formed in November 2024. …

Masthead

Missouri Law Review

No abstract provided.

The Varying Strength Of Parental Rights, Mark Strasser

Missouri Law Review

The United States Supreme Court has recognized that parental rights implicate fundamental interests and that statutes adversely affecting those rights require close examination. However, the Court has been inconsistent in both its analysis and results when deciding which statutes burdening parental rights nonetheless pass constitutional muster. The Court’s ambivalence and lack of clarity have made parental rights jurisprudence confused and confusing, as illustrated by the dissensus among the state supreme courts regarding which visitation statutes are constitutional. Yet, this jurisprudential quagmire cannot be blamed on one particular decision, as if a single clarification or modification could resolve the problem. Rather, …

Deliberate Indifference Reimagined: Towards An Objective Standard For Eighth Amendment Prison Condition Violations, Lane Hines Woodke

Missouri Law Review

This Article critiques the existing standard for establishing deliberate indifference under the Eighth Amendment, which primarily relies on the subjective intent of correctional officials. It argues for a shift towards an objective standard that assesses the reasonableness of state responses to known risks, particularly in light of persistent unconstitutional conditions within correctional facilities, such as inadequate living conditions and unchecked violence. The Article contends that the current subjective approach creates an insurmountable evidentiary burden for incarcerated individuals and fails to ensure meaningful compliance with constitutional protections. By advocating for an objective framework akin to standards used in Fourth and Fourteenth …

The Politics Of Preservation: Federal Implications Of The Smithsonian Executive Order, Autumn H. Duncan

Missouri Law Review

When society thinks of the phrase “revisionist history,” George Orwell’s harrowing words likely come to mind. The term itself is used in the political realm as “an accusation of deliberately distorting irrefutable historical ‘facts’ to serve a particular political agenda or viewpoint.” Although the topic of revisionism is a hot-button issue among historians and non-historians alike, Americans are divided over how to approach history. About 47% of the population believes that history should question the nation’s past, while 53% contend that history should celebrate it. This divide becomes even more evident when broken down by party lines: 84% of Republicans …

Product Liability In The Digital Age: A Flexible Framework For Categorizing Technology After Ameer V. Lyft, Andrew Jensen

Missouri Law Review

A single line of code can now cause a car crash, deny a loan, or—as in the case of Ameer v. Lyft—contribute to a man’s death. Traditional product liability law, born in the era of smokestacks and assembly lines, still assumes that only tangible things can be defective products. When software replaces machinery and algorithms make life-or-death decisions, courts face a question: can code itself be a defective product? The answer matters enormously. If courts decline to treat mass-marketed applications as “products,” victims of dangerous software may be left without recourse. On the other hand, if they expand liability too …

An Unnecessary Burden: Why It Is Time To Eliminate Mcdonnell Douglas From Ada Failure-To-Accommodate Claims, Jonathan G. Jain

Missouri Law Review

Several strangers sit together in a room, staring at three black lines on a white card. Their task seems simple: choose the line that matches the length of a line printed on a second card. One by one, the strangers correctly choose the matching line, and the task repeats with new white cards and new black lines. The correct answer is always obvious, but after a few rounds, one man suddenly finds himself alone in giving the correct response. What he does not know is that the others have been instructed to begin choosing incorrect lines. Eventually, despite what his …

Purpose Over Perception: Distinguishing Status From Viewpoint In A University’S Limited Public Forum, Haleigh J. Bachman

Missouri Law Review

In nearly every university, cultural centers and student organizations quietly provide tangible, essential support: one student finds a community to celebrate his shared heritage; another student finds guidance after struggling to obtain her necessary accommodations in class; an international student rehearses for a cultural showcase that will be the highlight of his semester. These spaces provide community, safety, and a sense of belonging that classrooms and lecture halls often do not. Nevertheless, public universities often face challenges in allocating physical space and funding resources to student organizations— particularly to those supporting cultural and affinity groups. On one hand, universities can …

Table Of Contents

Missouri Law Review

No abstract provided.

Impact Of Gender Trends On Plastic Surgery Fellowship Match: Implications For Surgical Education, Irene Helenowski, Emily Miller, Bridget Foley, Victoria Hodkiewicz, Christopher Kujalowicz, Parinaz Jila Siemers, Bianca Di Chiaro, Eleanor Bucholz

Biostatistics Collaborative Core: Faculty Publications and Other Works

Background:

No prior study has evaluated gender trends within the plastic surgery subspecialty fellowship match. The purpose of this study is to examine gender trends across fellowship trainee demographics to assess and characterize existing disparities between male and female plastic surgeon counterparts.

Methods:

A review of the new board diplomates listed in the annual newsletter to diplomates of the American Board of Plastic Surgery from 2015 to 2019 was used to identify physicians who pursued various plastic surgery subspecialties. Fellowship match data, including sex, practice type, and prior residency training, were obtained from publicly accessible institutional and private practice websites, …

The First 3 Years: Novice Teacher Perspectives On Staying In Education, Tammy M. Allen

Electronic Theses and Dissertations

Teacher attrition presents a persistent challenge for educational systems, with novice teachers leaving the profession at disproportionately high rates during their first 5 years. Rural schools face compounded difficulties in recruiting and retaining qualified educators due to geographic isolation, limited resources, and additional workload demands. The purpose of this qualitative study was to investigate novice secondary teachers’ perceptions of factors influencing their intent to remain in education. In this study, self-determination theory, which examines autonomy, competence, and relatedness as psychological needs supporting intrinsic motivation, and four capital theory, which addresses human, social, structural, and positive psychological capital as interconnected components …

Digital Assessment Of Subtractive And Additive Cad/Cam Fabrication Methods On The Fit And Accuracy Of Lithium Disilicate Veneers, Sara Fikry Elshafei Dr, Islam Heiba Dr, Basma Fayyad, Maha Nagy

Dentistry

No abstract provided.

Prevalence Profile Perceived Stress And Impact On Quality Of Life For Recurrent Aphthous Ulcers: A Cross-Sectional Epidemiological Study In Egypt, Dalia Ghalwash

Dentistry

Recurrent Aphthous Ulcerations (RAU) are among the most frequent oral ulcers with unknown etiology and multiple risk factors. This study assessed the prevalence profile of aphthous ulcers, risk factors, levels of perceived stress, and their impact on quality of life in an Egyptian sample. This study involved screening 4100 individuals from the outpatient clinic, Faculty of Dentistry, The British University in Egypt, and several Egyptian governorates. Patients were subjected to clinical examination and patient interviews for accurate diagnosis and collection of data. The Perceived Stress Scale (PSS) was used to assess levels of perceived stress, and the Oral Health Impact …

New Book Explores Small Talk, Big Silence In Evangelical Communities, Clara Turnage

University of Mississippi News

OXFORD, Miss. – In a new book, University of Mississippi sociologist Amy McDowell says small talk can be used as a tool to block meaningful conversation in the evangelical church, leaving some people feeling isolated in their beliefs that conflict with Christian nationalism.

Ready-To-Teach Reads: Standards-Aligned Novel Studies For Seventh Grade Using Contemporary Middle Grade Fiction, Elizabeth Duvall

Senior Theses

This project aims to provide middle school English teachers with an easy way to update their curriculum to be culturally relevant using ready-to-teach unit plans based on diverse novels. Since research shows students benefit from reading texts from diverse cultures, each novel features minority voices. Both units include lesson plans for each day, and resources like slideshows, worksheets, and discussion questions. They were created using the South Carolina College and Career Ready Standards for English Language Arts. While these units are tailored to South Carolina teachers, they can be used by any educator whose standards align with the units’ learning …

Designing Surface-Induced Entatic States In Copper Complexes For Tunable Reactivity, Rachel Kiser

Senior Theses

Copper catalysts play an important role in electrocatalytic oxidation reactions due to their redox flexibility and relative abundance compared to noble metal catalysts. In biological systems, copper metalloenzymes often achieve enhanced reactivity through an entatic state. Entasis is described as an active site or metal center being constrained to a geometric and electronic state, minimizing primary sphere reorganization energy and achieving higher rates of electron transfer.  This study investigates whether entasis can be achieved in synthetic molecular catalysts by immobilizing Cu(I) complexes onto metal oxide surfaces. Two Cu(I) complexes bearing carboxylate-functionalized ligands were examined both in homogeneous solution and when …

Searching For Temporal Variations In The Fine-Structure Constant Using Espresso Spectrograph Data, David Hoffman Iv

Senior Theses

The fine-structure constant α is a dimensionless constant, defined as e²/(4πε₀ℏc) ≈ 1/137. On the order of human timescales, its value is very much unchanging, however, in recent years there has been extensive debate over whether or not the value of α has remained constant over cosmological timescales. With the natural corollary to a changing α being that either one or multiple of its constituent physical constants have also changed in value, observing a variation in the fine-structure constant would have vast ramifications for our understanding of the nature of the early universe and how it has evolved. While past …

Graphene Synthesis: A Reactor-Oriented Review Of Conventional And Emerging Production Methods, Paul C. Ani, Zeyad Zeitoun, Hasan J. Al-Abedi, Joseph D. Smith

Chemical and Biochemical Engineering Faculty Research & Creative Works

Graphene's unparalleled electrical, mechanical, and thermal properties have positioned it as a transformative material across diverse sectors, including electronics, energy storage, biomedicine, and environmental remediation. However, scalable, cost-effective, and high-quality production remains a critical challenge. This review presents a comprehensive, reactor-oriented analysis of both conventional and emerging graphene synthesis methods, categorized into top-down and bottom-up approaches. Special emphasis is placed on the role of reactor configurations in determining product quality, layer control, scalability, and economic viability. Key synthesis techniques explored include chemical vapor deposition (CVD), epitaxial growth, electrochemical exfoliation, ultrasonic-assisted methods, microwave reactors, combustion synthesis, and plasma-enhanced processes. By evaluating …

Feasibility Of Identifying Factors Related To Alzheimer’S Disease And Related Dementia In Real-World Data, Yu Huang, Qian Li, Aokun Chen, Yongqiu Li, Yu-Neng Chuang, Xia Hu, Serena Jingchuan Guo, Xing He, Yijiang Pang, Jiayu Zhou, Yonghui Wu, Yi Guo, Jiang Bian

Faculty, Staff and Student Publications

Objective: This study aimed to provide a comprehensive understanding of factors associated with Alzheimer's disease (AD) and AD-related dementias (AD/ADRD), which could aid in studies to develop new treatments for AD/ADRD patients and identify high-risk populations for prevention.

Scope and method: In our study, we summarized the risk factors for AD/ADRD by reviewing existing meta-analyses and review articles on risk and preventive factors for AD/ADRD. From this literature review and the identified AD/ADRD factors, we examined the accessibility of these risk and preventive factors in both structured and unstructured Electronic Health Records (EHRs) data.

Results: In total, we extracted 401 …

Retreat, Renew, Reflect: Exploring Digital Marketing Strategies For Faith-Based Retreat Centers, Rebecca A. Mickler

Electronic Theses and Dissertations

In today’s fast-paced world, retreat centers offer a vital opportunity for rest, reflection, and spiritual renewal. Despite growing societal awareness of mental health and wellness, many religiously affiliated retreat centers face stagnant participation, aging leadership, and operational challenges that threaten their long-term sustainability. This qualitative-dominant mixed methods study uses bright spots analysis to examine how Villa Maria Education and Spirituality Center (VMESC), a Catholic retreat center, can strengthen its digital marketing strategies to attract new audiences while maintaining mission alignment.

Bright spots analysis examines positive outliers, organizations that achieve notable success despite operating within similar constraints, to identify practices that …

Mathematics In Crisis: Predictors Of Achievement For Black And Latino High School Students Post-Covid-19, David Mikel Etheridge

Dissertations

This quantitative study examines systemic factors predicting math achievement for Black and Latino high school students in Chicagoland's 2025 graduating class, using public Illinois School Report Card data. It identifies teacher qualifications, chronic absenteeism, and school ratings as statistically significant predictors, confirming systemic inequities. The study advocates for structural policy reform, targeted teacher investment, and culturally responsive pedagogy to achieve equity and disrupt barriers for marginalized students.

Examining The Impact Of Restorative Practices On Student Behavior, Discipline, And Relationships In A K–5 Elementary School, Kathleen Tomaszewski

Dissertations

This study examined the implementation of restorative practices in a K–5 elementary school and their influence on student behavior, disciplinary actions, and teacher–student relationships. Restorative practices in schools focus on building a positive school climate and addressing student behavior through community and relationship-building rather than punitive measures. The rationale for the study was grounded in concerns regarding the use of exclusionary discipline practices and the need for proactive, student-centered approaches to improving school climate. Two main research questions guided the inquiry: To what extent do restorative practices impact student referrals and disciplinary actions in a K-5 elementary school? How do …

Appellate Review Of Child Custody In Mississippi, 1994-2024, Eleanor Detweiler

Honors Theses

This study examines changes in child custody decision-making within the Mississippi appellate court system over a thirty-year period, with a particular focus on the role of legal custody as a separate consideration from physical custody. Using a longitudinal empirical research design, appellate court decisions from 1994, 2004, 2014, and 2024 were analyzed using Nexis Uni. Cases were identified using the search term “child custody” with emphasis on case headnotes indexed under “child custody” as the area of law. Variables including party roles, types of custody sought, reasons for appeal, and case outcomes were recorded and evaluated to identify trends over …

Life Cycle Costing Of Modular Timber Residential Construction, Logan Micah Hammel

Construction Management

This study examines the economic feasibility of modular residential construction using life-cycle costing (LCC) and life-cycle assessment (LCA) approaches to assess the sustainability and maintenance costs of modular construction. Using the structures and documents from the Gateway Decathlon project as the subject, we applied LCC formulas and programs to assess their economic performance. These calculations were conducted manually in Excel and modeled using the OpenLCA platform to compare traditional and software-based approaches. The study aims to identify cost drivers across building scopes, such as building materials and electrical and mechanical systems, and to evaluate how modular construction performs over its …