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College Of Business News, Georgia Southern University

College of Business: News & Publications

• Parker Alumni Talk About Tenet Advisors, a Startup Company Offering Integrated Family Office Solutions
• Alumna Spotlight: Courtney Ashley

Strengthen Building Of Basic Reach Capacity For Semiconductor Research To Light Up “Beacon” Towards Realizing The Self-Reliance And Self-Improvement Of Semiconductors, Junwei Luo, Shushen Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Upgrading Allocation And Management Of S&T Funding, Improving Efficiency Of S&T Investment, Wenjun Liu, Geng Li, Fengyu Huang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The main focus of China's science and technology (S&T) investment has shifted from the lack of total investment to solve the contradiction between the need for high-quality development and the inefficiency of investment. In order to enhance the efficiency of S&T investment, the structural, institutional, and managerial problems should be solved. Based on the requirement of "enhancing the efficiency of S&T investment" raised at the 20th National Congress of the CPC, the study analyzes the main contradictions in China's S&T investment and factors that restrict the efficiency of S&T investment, and puts forward policy suggestions.

Practice And Thinking Of Agency Level Budget Performance Evaluation Pilot In Chinese Academy Of Sciences, Hao Tang, Ruhan A, Jun He, Kaiyue Feng, Jun Gao

Bulletin of Chinese Academy of Sciences (Chinese Version)

In accordance with the request of Ministry of Finance, Chinese Academy of Sciences (CAS) conducts a pilot study of comprehensive budget performance evaluation among six affiliated institutes of CAS. The research gives a systematic reviewing analysis from the perspectives of the background of the pilot study, construction of the evaluation logic model, design of the evaluation indicator system, organization and implementation of the whole pilot study, and the resulted effects thereof based on the specific practices. In the meantime, upon exploring of issues, including but not limited to, coordination of all kinds of evaluation work, the uniqueness of science and …

Analysis And Thinking On Developing Evolution Of National Innovation System, Defang He, Fuqiang Tang, Tao Chen, Xianfeng Luo, Fangjuan Yang

Bulletin of Chinese Academy of Sciences (Chinese Version)

As an important support for national security and socio-economic development, the national innovation system has been evolving continuously in the process of long-term historical evolution and selective construction. Based on the law of science and technology development, this study combines history study and logical analysis, and reveals the universal law and general trend of the national innovation system. Under the new development situation, this study also puts forward a common framework of national innovation system. The construction practice of China's national innovation system is summarized and suggestions are put forward to improve the overall efficiency of national innovation system.

Nsfc Encourages Female Scientists To Grow: Policy, Effectiveness And Prospects, Xuan Yu, Ruiping Gao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Women are a key force in the scientific and technological research workforce. Since 2010, the National Natural Science Foundation of China (NSFC) has launched a series of measures to support female researchers, which have been widely praised by the scientific and technological community. For ten years since the policy was implemented, the NSFC has gradually become the cradle for the growth of female researchers. It has increased the participation of women in scientific research, increased the opportunities for breastfeeding women to apply for and receive funding, and boosted the growth and development of high-level female researchers. Significant achievements have been …

Integrated Ecological Protection And Restoration In The Guangdong-Hong Kong-Macao Greater Bay Area: Thoughts And Suggestions, Jun Wang, Jian Peng, Bojie Fu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The 20th Party Congress made a significant proposal:"advance the Beautiful China Initiative and take a holistic and systematic approach to the conservation and improvement of mountains, waters, forests, farmlands, grasslands, and deserts". The establishment of a sustainable national economy and ecological civilization is a major priority for the Guangdong-Hong Kong-Macao Greater Bay Area (GBA). The GBA's current land development and protection situation is briefly summarized in the study, which also analyzes the issues with ecological protection and restoration in terms of whole-factor chain management, cross-regional cooperation, and target patterns. From the viewpoints of the system view, holistic view, synergy view, …

Causes, Countermeasures And Enlightenment Of “Eu Semiconductor Crisis”: Interpretation Around The European Chips Act, Junfeng Li, Ying Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The European Union (EU) is one of the origins of the global semiconductor industry, but due to its structural defects in the semiconductor value chain, it has encountered a crisis of chip shortages and supply cuts since 2021. The European Chips Act drafted by EU proposes a path for semiconductor ecological construction, crisis intervention regulatory measures, and outlines a blueprint for a "national system for the chip industry with EU characteristics". These factors are of speculative significance and reference value for China to balance the relationship between the government and the market, subsidies and competition, key construction and inclusive support …

Analysis On Bottleneck And Prospect Of Integrated Circuit Talent Training Oriented To Sci-Tech Self-Reliance And Self-Strengthening At Higher Levels, Kaixuan Guan, Jiang Yu, Jianzhong Zhou, Feng Chen, Yan Han

Bulletin of Chinese Academy of Sciences (Chinese Version)

The most essential feature of building a new development paradigm is to achieve sci-tech self-reliance and self-strengthening at higher levels. The integrated circuit industry, as an important pillar to achieve this essential feature, is facing a severe external situation. China's chip shortage pain begins with a shortage of talents. The structural problem of uneven development at the overall level of the industry makes it more difficult to effectively gather and distribute talents. To achieve sci-tech self-reliance and self-strengthening at higher levels, we need to be both demand-oriented and problem-oriented, which means not only to pay attention to the core technology …

Pollution Control And Carbon Reduction In Whole Industrial Process: Method, Strategy And Scientific Basis, Hongbin Cao, He Zhao, Yuehong Zhao, Di Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

As China's environmental protection emission standards are becoming stricter and industrial parks are taking shape, problems such as the lack of stable cooperative treatment technology for toxic pollutants and carbon emission reduction, and the high control cost seriously restrict the sustainable development of economic society and the realization of the strategic goal of carbon emission reduction. Guided by the major environmental protection demand of industries, this study put forward the method, strategy and scientific basis of "Synergistic reduce pollution and carbon in the whole process of industry". Through the coordination of control methods, cross-media, multi-field and multi-factor modeling optimization, the …

Policy Overview (January, 2023)

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Cover 3

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Cover 4

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

The Rider (2023-02-20), Verilu Infante

The Rider Archives

Vol.8 No.20

State Variation In Squamous Cell Carcinoma Of The Anus Incidence And Mortality, And Association With Hiv/Aids And Smoking In The United States, Haluk Damgacioglu, Yueh-Yun Lin, Ana Patricia Ortiz, Chi-Fang Wu, Zahed Shahmoradi, Shiang Shiuan Shyu, Ruosha Li, Alan G Nyitray, Keith Sigel, Gary M Clifford, Naomi Jay, Vivian Colon Lopez, Gregory M Barnell, Elizabeth Y Chiao, Elizabeth A Stier, Karen J Ortiz-Ortiz, Jeslie M Ramos-Cartagena, Kalyani Sonawane, Ashish A Deshmukh

Faculty, Staff and Student Publications

PURPOSE: Squamous cell carcinoma of the anus (SCCA) incidence and mortality rates are rising in the United States. Understanding state-level incidence and mortality patterns and associations with smoking and AIDS prevalence (key risk factors) could help unravel disparities and provide etiologic clues.

METHODS: Using the US Cancer Statistics and the National Center for Health Statistics data sets, we estimated state-level SCCA incidence and mortality rates. Rate ratios (RRs) were calculated to compare incidence and mortality in 2014-2018 versus 2001-2005. The correlations between SCCA incidence with current smoking (from the Behavioral Risk Factor Surveillance System) and AIDS (from the HIV Surveillance …

Modules, Mandates, & Morals: A Self-Study Of The Creation Of An Online Secondary Holocaust Course, Alexander C. Ledford

USF Tampa Graduate Theses and Dissertations

This dissertation examines the process of the analysis, design, development, implementation, and evaluation of an online secondary Holocaust education course. Employing self-study methodology, it critically examines the decision-making of the researcher as they engage in the tasks of each phase of the ADDIE model of instructional. Special attention has been paid to the intersection of prevailing pedagogical and curricular recommendations from scholars in the fields of both Holocaust education and instructional design, a practice that has not received adequate scholarly attention. Drawing upon both bodies of literature, the researcher stresses the use of pedagogical practices which are put forward as …

Data Associated With 'Rowney Et Al. (2023). Historical Anthropogenic Disturbances Explain Long-Term Moorland Vegetation Dynamics. Ecology And Evolution', Francis Rowney, Ralph Fyfe, Leonard Baker, Henry French, Martha Hall, Havananda Ombashi, Rhys Timms

Faculty of Science and Engineering Datasets

https://www.plymouth.ac.uk/research/centre-for-research-in-environment-and-society-ceres/reclaiming-exmoor Dataset Description: Data associated with 'Rowney et al. (2023). Historical anthropogenic disturbances explain long-term moorland vegetation dynamics. Ecology and Evolution' Citation: Rowney, F. et al. (2023). Data associated with 'Rowney et al. (2023). Historical anthropogenic disturbances explain long-term moorland vegetation dynamics. Ecology and Evolution'. PEARL Research Repository https://doi.org/10.24382/0ps2-6t74

The George-Anne Reflector Magazine Newsletter, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Decision-Making Under Risk And Theory Of Mind In Adolescent Offenders In Provisional Deprivation Of Liberty, Rubens José Loureiro, Flavio Takemi Kataoka, Thiago Wendt Viola, Gisele Iesbich Vargas, Breno Sanvicente-Vieira, Rodrigo Grassi-Oliveira, Bruno Kluwe-Schiavon

Faculty, Staff and Student Publications

INTRODUCTION: Delinquent behaviors are risky behaviors that increase during puberty and reach their highest peak in late adolescence. It has been proposed that poor decision-making and theory of mind (ToM) are key cognitive processes implicated with delinquency during adolescence, affecting evaluation of risks and impairing appreciation of social norms. Nevertheless, it is not yet clear whether adolescent offenders who are subjected to provisional deprivation of liberty due to conflict with the law (adolescents in conflict with the law [ACL]) might, in fact, present a specific profile with regard to these cognitive processes.

OBJECTIVES: To assess deliberative decision-making and ToM among …

Identification Of And Mechanistic Insights Into Sars-Cov-2 Main Protease Non-Covalent Inhibitors: An In-Silico Study, Jian-Xin Shen, Wen-Wen Du, Yuan-Ling Xia, Zhi-Bi Zhang, Ze-Fen Yu, Yun-Xin Fu, Shu-Qun Liu

Faculty, Staff and Student Publications

The indispensable role of the SARS-CoV-2 main protease (Mpro) in the viral replication cycle and its dissimilarity to human proteases make Mpro a promising drug target. In order to identify the non-covalent Mpro inhibitors, we performed a comprehensive study using a combined computational strategy. We first screened the ZINC purchasable compound database using the pharmacophore model generated from the reference crystal structure of Mpro complexed with the inhibitor ML188. The hit compounds were then filtered by molecular docking and predicted parameters of drug-likeness and pharmacokinetics. The final molecular dynamics (MD) simulations identified three effective candidate inhibitors (ECIs) capable of maintaining …

Differential Regulation Of H3k9/H3k14 Acetylation By Small Molecules Drives Neuron-Fate-Induction Of Glioma Cell, Xincheng Liu, Cui Guo, Tiandong Leng, Zhen Fan, Jialuo Mai, Jiehong Chen, Jinhai Xu, Qianyi Li, Bin Jiang, Ke Sai, Wenzhuo Yang, Jiayu Gu, Jingyi Wang, Shuxin Sun, Zhijie Chen, Yingqian Zhong, Xuanming Liang, Chaoxin Chen, Jing Cai, Yuan Lin, Jiankai Liang, Jun Hu, Guangmei Yan, Wenbo Zhu, Wei Yin

Faculty, Staff and Student Publications

Differentiation therapy using small molecules is a promising strategy for improving the prognosis of glioblastoma (GBM). Histone acetylation plays an important role in cell fate determination. Nevertheless, whether histone acetylation in specific sites determines GBM cells fate remains to be explored. Through screening from a 349 small molecule-library, we identified that histone deacetylase inhibitor (HDACi) MS-275 synergized with 8-CPT-cAMP was able to transdifferentiate U87MG GBM cells into neuron-like cells, which were characterized by cell cycle arrest, rich neuron biomarkers, and typical neuron electrophysiology. Intriguingly, acetylation tags of histone 3 at lysine 9 (H3K9ac) were decreased in the promoter of multiple …

A Mathematical Investigation Of Landauer’S Principle, Paul Bracken

School of Mathematical & Statistical Sciences Faculty Publications

A minimal mathematical approach is used to state Landauer’s principle in a precise, general way. The results are obtained by means of a rigorous development which is based on the use of quantum statistical mechanics. A mathematical form of the principle results as an equality rather than an inequality. The equality version does imply the original statement of the principle as introduced by Landauer.

Investigative Interviews – A Refresher For Investigators, Alan Saquella

Publications

Whether you are interviewing a suspect, witness, or victim, let us review some basic reminders to make your investigative interviews more productive and successful in obtaining factual and truthful information.

To start understanding yourself.

Check your personal biases and prejudices at the door. Going in with your mind ready and set on a conclusion can lead you down the wrong path and waste valuable time.

Do Bankrupt Firms Recognize Publicly Available Bad News In A Timely Fashion?, Mariem Khalifa, Samir Trabelsi

All Works

Abstract

Purpose – The purpose of this paper is to examine whether managers of bankrupt firms are more or less conditionally conservative in their financial reporting relative to non-bankrupt firms. The study further examines the cross-sectional differences in conditional conservatism among bankrupt and non-bankrupt firms. Design/methodology/approach – The study employs a sample of US firms to investigate conditional conservatism in firms that experience financial distress and go bankrupt relative to non-stressed non-bankrupt firms. The study also uses switching regression models to identify the drivers of the cross-sectional difference in conditional conservatism among bankrupt and non-bankrupt firms. Findings – Empirical results …

Tcr-Engineered Adoptive Cell Therapy Effectively Treats Intracranial Murine Glioblastoma, Maximilian O. Schaettler, Rupen Desai, Anthony Z. Wang, Alexandra J. Livingstone, Dale K. Kobayashi, Andrew T. Coxon, Jay A. Bowman-Kirigin, Connor J. Liu, Mao Li, Diane E. Bender, Michael J. White, David M. Kranz, Tanner M. Johanns, Gavin P. Dunn

2020-Current year OA Pubs

BACKGROUND: Adoptive cellular therapies with chimeric antigen receptor T cells have revolutionized the treatment of some malignancies but have shown limited efficacy in solid tumors such as glioblastoma and face a scarcity of safe therapeutic targets. As an alternative, T cell receptor (TCR)-engineered cellular therapy against tumor-specific neoantigens has generated significant excitement, but there exist no preclinical systems to rigorously model this approach in glioblastoma.

METHODS: We employed single-cell PCR to isolate a TCR specific for the Imp3

RESULTS: We isolated and characterized the 3×1.1C TCR that displayed a high affinity for mImp3 but no wild-type cross-reactivity. To provide a …

Hydrogel Encapsulation Of Genome-Engineered Stem Cells For Long-Term Self-Regulating Anti-Cytokine Therapy, Kelsey H Collins, Lara Pferdehirt, Leila S Saleh, Alireza Savadipour, Luke E Springer, Kristin L Lenz, Dominic M Thompson, Sara J Oswald, Christine T N Pham, Farshid Guilak

2020-Current year OA Pubs

Biologic therapies have revolutionized treatment options for rheumatoid arthritis (RA) but their continuous administration at high doses may lead to adverse events. Thus, the development of improved drug delivery systems that can sense and respond commensurately to disease flares represents an unmet medical need. Toward this end, we generated induced pluripotent stem cells (iPSCs) that express interleukin-1 receptor antagonist (IL-1Ra, an inhibitor of IL-1) in a feedback-controlled manner driven by the macrophage chemoattractant protein-1 (Ccl2) promoter. Cells were seeded in agarose hydrogel constructs made from 3D printed molds that can be injected subcutaneously via a blunt needle, thus simplifying implantation …

Management Of Local Contents In Institutional Repositories In Libraries In Tertiary Institutions In Nigeria: A Survey., Doris Aghoghovwia, Chinwe Augustina Ekereuche Mrs

Library Philosophy and Practice (e-journal)

The purpose of this study is to investigate the development and management of local contents in institutional repositories (IR) in tertiary institution libraries in Nigeria. The study adopted a survey research method. Online questionnaire and IR site investigation methods were used to collect data from 20 university libraries in Nigeria. The study revealed that no single College of Education, or Polytechnic library in Nigeria have embraced development of IR. Only 20 university libraries have successfully developed IRs to manage local contents emanating from the universities. The majority of the institutional repositories contain primarily theses and dissertations, journal articles and conference …

Repurposing Atovaquone As A Therapeutic Against Acute Myeloid Leukemia (Aml): Combination With Conventional Chemotherapy Is Feasible And Well Tolerated, Alexandra Mclean Stevens, Eric S Schafer, Minhua Li, Maci Terrell, Raushan Rashid, Hana Paek, Melanie B Bernhardt, Allison Weisnicht, Wesley T Smith, Noah J Keogh, Michelle C Alozie, Hailey H Oviedo, Alan K Gonzalez, Tamilini Ilangovan, Alicia Mangubat-Medina, Haopei Wang, Eunji Jo, Cara A Rabik, Claire Bocchini, Susan Hilsenbeck, Zachary T Ball, Todd M Cooper, Michele S Redell

Center for Medical Ethics and Health Policy Staff Publications

Survival of pediatric AML remains poor despite maximized myelosuppressive therapy. The pneumocystis jiroveci pneumonia (PJP)-treating medication atovaquone (AQ) suppresses oxidative phosphorylation (OXPHOS) and reduces AML burden in patient-derived xenograft (PDX) mouse models, making it an ideal concomitant AML therapy. Poor palatability and limited product formulations have historically limited routine use of AQ in pediatric AML patients. Patients with de novo AML were enrolled at two hospitals. Daily AQ at established PJP dosing was combined with standard AML therapy, based on the Medical Research Council backbone. AQ compliance, adverse events (AEs), ease of administration score (scale: 1 (very difficult)-5 (very easy)) …

Nurses' Understanding And Management Of Iron Deficiency In Australia: A Cross-Sectional, Exploratory Study, Therese A. O'Sullivan, Pradeep H. Jayasuriya, Natalie Tsalis, Nina Calogero, Ramesh Manocha

Research outputs 2022 to 2026

Objectives: To assess the experiences and knowledge of nurses in the area of iron deficiency. Design: A cross-sectional, exploratory study using online survey. Setting: Data were collected from nurses working at various primary, secondary and tertiary Australian health practices and organisations. Participants: Australian nurses currently in practice. Method: Australian nurses currently in practice were invited to complete an online survey about their work background, personal experiences with iron deficiency and iron-deficiency identification and treatment. The survey included a nine-item questionnaire to assess knowledge of iron-deficiency risk factors and biochemistry. Results: A total of 534 eligible nurses participated in the survey. …