Digital Commons Network^™

Lunar Search And Rescue: The Next Step For Human Spaceflight Recovery, Benjamin J. Johnis

Theses and Dissertations

Humans return to the Moon in 2024 under the NASA Artemis mission. Commercial space explorations are rapidly expanding. The sudden increase of human spaceflight calls for increased emphasis on space rescue. These revelations drove an AFRL/AFIT capability gap assessment to provide specific proposals for a modern space rescue program guided by Transaction Cost Economics Theory. The mission analysis arms USSPACECOM and NASA to coordinate an interagency approach to Lunar Search and Rescue, positioning America to compete in the new space race. The strategic consequences of failing to act could fundamentally jeopardize American leadership in space.

Pattern Of Life Modeling On Maritime Vessels With Bayesian Inferencing, Miles A. Kelly

Theses and Dissertations

Despite decades of research, maritime traffic models’ limited predictive power continues to constrain their operational utility. We build on previous pattern of life modeling algorithms and contribute a Bayesian inferencing model for anomaly detection. Our probabilistic approach provides decision makers the capability to tailor the belief threshold for identifying anomalies and to enact a measured response based on the degree of abnormality. We perform a case study to evaluate the results, verifying that our Bayesian inferencing method accurately refines its probability when given the location and time of a ship of interest, and serving as a proof of concept for …

Uncertainty Quantification In Federated Learning For Persistent Post-Traumatic Headache, Byungmoo Brian Kim

Theses and Dissertations

A post-traumatic headache (PTH), resulting from a mild traumatic brain injury (mTBI), potentially develops into persistent post-traumatic headache (PPTH). Although no known cure for PPTH exists, research has shown that receiving treatment at earlier stages of PTH lowers the risk of patients developing PPTH. Previous studies have shown machine learning (ML) models capable of predicting a patient’s PTH progression, but none have considered the issue of protecting patient privacy. Due to patient privacy, ML models only have access to data within the institution. Federated learning (FL) harnesses data from separate institutions without sacrificing patient privacy as institutions can run ML …

Predicting Success Of Pilot Training Candidates Using Interpretable Machine Learning, Alexandra S. King

Theses and Dissertations

The United States Air Force (USAF) has struggled with a sustained pilot shortage over the past several years; senior military and government leaders have been working towards a solution to the problem, with no noticeable improvements. Both attrition of more experienced pilots as well as wash out rates within pilot training contribute to this issue. This research focuses on pilot training attrition. Improving the process for selecting pilot candidates can reduce the number of candidates who fail. This research uses historical specialized undergraduate pilot training (SUPT) data and leverages select machine learning techniques to determine which factors are associated with …

Air Force Cadet To Career Field Matching Problem, Ian P. Macdonald

Theses and Dissertations

This research examines the Cadet to Air Force Specialty Code (AFSC) Matching Problem (CAMP). Currently, the matching problem occurs annually at the Air Force Personnel Center (AFPC) using an integer program and value focused thinking approach. This paper presents a novel method to match cadets with AFSCs using a generalized structure of the Hospitals Residents problem with special emphasis on lower quotas. This paper also examines the United States Army Matching problem and compares it to the techniques and constraints applied to solve the CAMP. The research culminates in the presentation of three algorithms created to solve the CAMP and …

Simulating Autonomous Drone Swarm Behaviors In An Anti-Access Area Denial (A2ad) Environment, Alexander L. Martinez

Theses and Dissertations

Army senior military leaders are invested in acquiring modernized aerial platforms and equipment to augment the U.S. Army’s ability to overcome A2AD threats imposed by modern IADS. A prominent element of this modernization effort is the employment of autonomous drones to defeat IADS threats while minimizing risk to Army Soldiers. This research utilizes a framework for classifying the levels of autonomous capability along three dimensions: the ability to act alone, the ability to cooperate, and the ability to adapt. A virtual combat model, created using the AFSIM, simulates the engagement between an enemy IADS and a friendly formation comprised of …

Examining Fuel Service System Failures Of The Usaf R11 Using Survival Analysis, Roed M.S. Mejia

Theses and Dissertations

Recent events show that fuel supply is a large contributor to the success or failure of a military operation in response to a contingency. Any future near-peer conflict will stress the supply chain and require fully operational vehicles to be ready for the primary mission sets they support. In the United States Air Force (USAF), the readiness of fuel distribution trucks is crucial to meeting those mission sets in global operations. Utilizing non-parametric and semi-parametric survival models, which do not assume specific probability distributions, this study analyzes maintenance data for R-11 trucks that refuel aircraft.

A Transformer Based Architecture For Indonesian Sentiment Analysis - Exploring Indobert Variations, Training Size, And Self-Supervised Model Training, Connor F. Shaw

Theses and Dissertations

There is strong motivation in both civilian and military circles to understand the attitudes, motivations, feelings, and emotions of a population of interest. Social media is a rich source of self-disclosed information by individuals from all walks of life about virtually every domain of the human experience, but the vast quantity of data is impossible to effectively analyze without advanced natural language processing algorithms. This research creates a transfer learning based emotion classification model for Indonesian language Twitter data. Transfer learning consists of two steps: pre-training and fine tuning. Three variations of Indonesian Bidirectional Encoder Representations from Transformers (IndoBERT) are …

Analysis And Optimization Of Contract Data Schema, Franklin Sun

Theses and Dissertations

agement, development, and growth of U.S Air Force assets demand extensive organizational communication and structuring. These interactions yield substantial amounts of contracting and administrative information. Over 4 million such contracts as a means towards obtaining valuable insights on Department of Defense resource usage. This set of contracting data is largely not optimized for backend service in an analytics environment. To this end, the following research evaluates the efficiency and performance of various data structuring methods. Evaluated designs include a baseline unstructured schema, a Data Mart schema, and a snowflake schema. Overall design success metrics include ease of use by end …

Probability Of Agreement As A Simulation Validation Methodology, Matthew C. Ledwith

Theses and Dissertations

Determining whether a simulation model is operationally valid requires the rigorous assessment of agreement between observed functional responses of the simulation model and the corresponding real world system or process of interest. This research seeks to extend and formulate the probability of agreement approach to the operational validation of simulation models. The first paper provides a methodological approach and an initial demonstration which leverages bootstrapping to overcome situations where one’s ability to collect real-world data is limited. The second paper extends the probability of agreement approach to account for second-order heteroscedastic variability structures and establishes a weighted probability of agreement …

Concept Of Operations Of Cislunar Mirror Satellites To Provide Augmented Lighting Of Dim Space-Based Objects, Alec E. Cook

Theses and Dissertations

The imaging and inspection of Resident Space Objects (RSOs) is an increasingly important mission as space-faring nations and commercial enterprises alike seek to develop means to repair and refuel spacecraft, as well as de-orbit RSOs to reduce orbital debris. Lighting conditions are not always advantageous for an imaging/inspection or repair/refuel spacecraft; therefore, the use of mirror spacecraft to reflect solar energy is proposed to illuminate dimly lit RSOs. The present research investigates the efficacy of space-based reflectors at examining spacecraft in the cislunar environment. Specific assessments include target spacecraft in geosynchronous Earth orbit and periodic orbits around selected Lagrange points, …

Experimental And Computational Bearing Strength Of Fiber Metal Laminate With And Without Film Adhesive, Christopher L. Bellanova Jr.

Theses and Dissertations

This research characterized the performance of a fiber metal laminate composed of carbon fiber and stainless steel without film adhesive and compared it to a similar, previously tested, fiber metal laminate including film adhesive. Removal of the adhesive layers reduced the localized thickness, simplified manufacturing, and allowed for a 20% increase in foil thickness. Quasi-static testing was conducted in double shear, single shear protruding, and single shear countersunk configurations. The results were compared to adhesive hybrid and control samples. To study the affects of bolt tension, samples at low torque in double shear were also tested. Progressive failure samples revealed …

Suitability Of Earth-Moon Triangular Lagrange Point Orbits For Space Situational Awareness, Eric P. Burkhart

Theses and Dissertations

The second space race is looming on the horizon, and the Moon is again at center stage. All major space fairing nations have plans for future Lunar exploration, but this time with plans to stay. NASA’s Artemis program plans to put humans back on the Moon in 2025 and establish a Lunar base on the South pole in the 2030s. Meanwhile, China has landed a rover on the far side of the moon with a communications relay satellite in a halo orbit around the L2 Lagrange point, and partnered with Russia to build a Lunar research station on the Lunar …

Performance Analysis And Recommended Improvements Of A Cubesat Resistojet, Alexander M. Petrocelli

Theses and Dissertations

A small resistojet design was evaluated for its current performance and assessed for design and operational improvements. This resistojet is designed to operate on AFIT CubeSats with the intent of providing 100-200 mN of thrust at a specific impulse between 66-104 seconds. Using previously collected data and studies conducted on the design, analysis was performed to determine the current performance of this first-generation design. This provided a starting point for performance analysis over a variety of operational temperatures and pressures. This process was conducted for various heat exchanger path lengths of both the current design and two adapted path geometries. …

Gaseous Fuel Combustion In A Small Turbojet, Katherine A. Ashton

Theses and Dissertations

This project set out to test the suitability of natural gas as an aviation fuel by comparing how a small turbojet performed when run on traditional jet fuel versus methane. A JetCat P400, originally designed for jet fuel, was modified to run on methane. The modifications made did not succeed at getting the engine to run at normal operating speed on methane, but did get the engine to run at normal operating speeds using ethylene and ethane. It was determined a fuel and air mixing problem was hindering the engine performance when run on methane Future studies improving the fuel …

Anisotropic Characterization Of Additively Manufactured Ti 6-4 Via Tension, Compression, And Three Point Bend Experimentation, James M. Gunderson

Theses and Dissertations

Titanium's ability to fill existing material gaps because of its higher strength and higher melting temperature compared to other common materials used in aircraft structures requires a need to understand the behavior of the material. Titanium's properties and the development of additive manufacturing also open an opportunity for it to be used in aerospace systems of the future in applications where traditionally manufactured titanium cannot meet the desired system requirements. Compressive, tensile, and three point bend experimental data collected from this research under varying temperatures, print orientations, print layer build heights, and surface finishes were analyzed to determine favorable material …

Improving Accessibility And Efficiency Of Analytic Provenance Tools For Reverse Engineering, Caleb W. Richardson

Theses and Dissertations

Reverse engineering is a vital technique for identifying and mitigating cyber threats. Yet, despite its importance, reverse engineering is a time-consuming process. Provenance tools help to improve the workflow of reverse engineers by providing an accessible method of viewing their flow through a binary. The current state-of-theart provenance tool for reverse engineering software called SensorRE, leverages an external server, web browser, and a large array of javascript libraries. This thesis presents Provenance Ninja, a software reverse engineering tool developed in Python that runs directly within Binary Ninja. Provenance Ninja captures reverse engineers’ provenance data and provides an interactive graph within …

Mechanical Properties And Performance Of A Novel Nano-Engineered Unitized Composite With Quasi-Isotropic Layup, Brian Matthew Pudlo

Theses and Dissertations

Carbon nanotubes (CNTs) exhibit outstanding mechanical, electrical, and thermal properties, but are a challenge to effectively implement into macroscopic composites for aerospace applications. This research investigates the mechanical properties and performance of a newly developed hybrid NanoStitch composite, alongside a control polymer matrix composite, at room temperature. Both composite material systems investigated in this work have quasi-isotropic layup. Monotonic tension-tofailure, tension-tension fatigue, and creep tests were performed to characterize the performance of the composites under cyclic and sustained loading. Experimental results obtained for the quasi-isotropic NanoStitch composite were compared to those obtained for the quasi-isotropic control composite. The properties and …

Optimal Gyroid Infill For Space Launch, Jose R. Lopez Cordell

Theses and Dissertations

This research characterizes the optimal gyroid infill design for the 1st frequency response of composite sandwich panels. Structural performance may be improved by designing the gyroid infill within the sandwich panel to have a 1st mode resonance frequency above typical launch vehicle vibrations. Ensuring a component generates a natural frequency response above a designed threshold is mandatory for space launch systems to prevent damage. The gyroid, a Triply Periodic Minimal Surface (TPMS), has the potential to provide close to isotropic stiffness in the principal axes with a minimal amount of material, making it an attractive choice for this application. This …

Direct Collocation Methods For Comparison Of Aerothermodynamic Models Effect On Hypersonic Trajectory Optimization By The Process Of Continuation, Noor K. Khan

Theses and Dissertations

An algorithm was created to optimize trajectories of hypersonic glide vehicles with selected cost functions by applying the process of continuation to direct orthogonal collocation methods. The trajectory was optimized to maximize the range of launch position given a fixed terminal location. The hypersonic glide vehicle system dynamics were modeled with three-dimensional, three degree of freedom equations of motion assuming no thrust and a non-rotating Earth with the control as bank angle. Three aerothermodynamic models were compared when input as path constraints to calculate the stagnation point heating rate at the nose as well as integrated for heat load. Use …

Detonation Confinement In A Second-Generation Radial Rotating Engine, John T. Ursino

Theses and Dissertations

In recent years, Rotating Detonation Engines (RDEs) have been coupled with turbomachinery to harness the benefits of detonative combustion. A novel type of RDE, referred to as the disk or Radial RDE (RRDE), has been developed in pursuit of length and weight savings compared to a traditional annular flow RDE. This design includes a disk-shaped device within which reactants flow from the outer radius, detonate, and exit the inner radius. In this paper several modifications have been made to a previously tested RRDE to address issues that arose with the original design. The combustion chamber diameter has been increased to …

Critical Infrastructure System Resiliency Modeling Using Multi-Layer Network Optimization, Spencer R. Figge

Theses and Dissertations

ccurately modeling the interdependent operation of critical infrastructure systems is an effective and efficient way of proactively evaluating system vulnerabilities and resiliency. Infrastructure systems are designed to transport essential commodities from where they are produced to where they are consumed and network flow-based models are one of the most effective ways to simulate and quantify infrastructure performance. The literature is populated with proposed models that must balance accuracy of interdependent operations, capability to include real-world considerations, and computational cost. This research proposes an alternative network-flow based model called the Critical Infrastructure System Resiliency Model (CISRM) that focuses on modeling a …

Optimal Control Of Precision Airdrop Trajectories Using Direct Collocation And Analytical Methods, Edward J. Maxwell

Theses and Dissertations

The work herein investigates the preliminary designs of an optimal navigation controller for a scalable cylindrical airdrop system controlled with grid fins in planar motion. Precision airdrop capabilities are desired for a range of military and humanitarian missions. Fielded airdrop systems have not met desired performance objectives, particularly regarding accuracy. Direct collocation and analytical methods were utilized to solve the optimal control problem for the grid fin controlled precision airdrop system examined in this work. The optimal control problem was comprised of two phases: controlled descent and parachute descent. Minimum and maximum ranges for the system under varying wind fields …

Impacts Of Utensil Conditions On Consumer Perception And Acceptance Of Food Samples Evaluated Under In-Home Testing During The Covid-19 Pandemic, Asmita Singh, Han-Seok Seo

Food Science Faculty Publications and Presentations

Sensory professionals are looking for alternative ways to conduct laboratory sensory testing, especially central location testing (CLT), during the COVID-19 pandemic. One way could be conducting CLTs at home (i.e., in-home testing). It is questionable whether food samples under in-home testing should be presented in uniform utensils, as it does so under laboratory sensory testing. This study aimed to determine whether utensil conditions could affect consumer perception and acceptance of food samples evaluated under in-home testing. Sixty-eight participants (40 females and 28 males) prepared chicken-flavored ramen noodle samples and evaluated them for attribute perception and acceptance, under two utensil conditions, …

A Trpv4-Dependent Neuroimmune Axis In The Spinal Cord Promotes Neuropathic Pain, Xueming Hu, Lixia Du, Shenbin Liu, Zhou Lan, Kaikai Zang, Jing Feng, Yonghui Zhao, Xingliang Yang, Zili Xie, Peter L. Wang, Aaron M. Ver Heul, Lvyi Chen, Vijay K. Samineni, Yan-Qing Wang, Kory J. Lavine, Robert W. Gereau, Gregory F. Wu, Hongzhen Hu

2020-Current year OA Pubs

Microglia, resident macrophages of the CNS, are essential to brain development, homeostasis, and disease. Microglial activation and proliferation are hallmarks of many CNS diseases, including neuropathic pain. However, molecular mechanisms that govern the spinal neuroimmune axis in the setting of neuropathic pain remain incompletely understood. Here, we show that genetic ablation or pharmacological blockade of transient receptor potential vanilloid type 4 (TRPV4) markedly attenuated neuropathic pain-like behaviors in a mouse model of spared nerve injury. Mechanistically, microglia-expressed TRPV4 mediated microglial activation and proliferation and promoted functional and structural plasticity of excitatory spinal neurons through release of lipocalin-2. Our results suggest …

Nitric Oxide-Driven Modifications Of Lipoic Arm Inhibit Α-Ketoacid Dehydrogenases, Gretchen L Seim, Steven V John, Nicholas L Arp, Zixiang Fang, David J Pagliarini, Jing Fan

2020-Current year OA Pubs

Pyruvate dehydrogenase complex (PDHC) and oxoglutarate dehydrogenase complex (OGDC), which belong to the mitochondrial α-ketoacid dehydrogenase family, play crucial roles in cellular metabolism. These multi-subunit enzyme complexes use lipoic arms covalently attached to their E2 subunits to transfer an acyl group to coenzyme A (CoA). Here, we report a novel mechanism capable of substantially inhibiting PDHC and OGDC: reactive nitrogen species (RNS) can covalently modify the thiols on their lipoic arms, generating a series of adducts that block catalytic activity. S-Nitroso-CoA, a product between RNS and the E2 subunit's natural substrate, CoA, can efficiently deliver these modifications onto the lipoic …

Society For Immunotherapy Of Cancer (Sitc) Consensus Definitions For Resistance To Combinations Of Immune Checkpoint Inhibitors With Chemotherapy, Naiyer Rizvi, Foluso O. Ademuyiwa, Z Alexander Cao, Helen X. Chen, Robert L. Ferris, Sarah B. Goldberg, Matthew D. Hellmann, Ranee Mehra, Ina Rhee, Jong Chul Park, Harriet Kluger, Hussein Tawbi, Ryan J. Sullivan

2020-Current year OA Pubs

Although immunotherapy can offer profound clinical benefit for patients with a variety of difficult-to-treat cancers, many tumors either do not respond to upfront treatment with immune checkpoint inhibitors (ICIs) or progressive/recurrent disease occurs after an interval of initial control. Improved response rates have been demonstrated with the addition of ICIs to cytotoxic therapies, leading to approvals from the US Food and Drug Administration and regulatory agencies in other countries for ICI-chemotherapy combinations in a number of solid tumor indications, including breast, head and neck, gastric, and lung cancer. Designing trials for patients with tumors that do not respond or stop …

Clinical Pattern Of Tolvaptan-Associated Liver Injury In Trial Participants With Autosomal Dominant Polycystic Kidney Disease (Adpkd): An Analysis Of Pivotal Clinical Trials, David H Alpers, James H Lewis, Christine M Hunt, James W Freston, Vicente E Torres, Hui Li, Wenchyi Wang, Molly E Hoke, Sharin E Roth, Lucas Westcott-Baker, Alvin Estilo

2020-Current year OA Pubs

RATIONALE & OBJECTIVE: Tolvaptan is associated with risk of drug-induced liver injury when used to treat autosomal dominant polycystic kidney disease (ADPKD). After this risk was described based on the clinical trials TEMPO 3:4 and TEMPO 4:4, additional data from the REPRISE trial and a long-term extension of TEMPO 4:4, REPRISE, and other tolvaptan trials in ADPKD have become available. To further characterize the hepatic safety profile of tolvaptan, an analysis of the expanded dataset was conducted.

STUDY DESIGN: Analysis of safety data from prospective clinical trials of tolvaptan.

SETTING & PARTICIPANTS: Multicenter clinical trials including more than 2,900 tolvaptan-treated …

Venographic Classification And Long-Term Surgical Treatment Outcomes For Axillary-Subclavian Vein Thrombosis Due To Venous Thoracic Outlet Syndrome (Paget-Schroetter Syndrome), Esmaeel Reza Dadashzadeh, J. Westley Ohman, Pavan K. Kavali, Karen M. Henderson, Danita M. Goestenkors, Robert W. Thompson

2020-Current year OA Pubs

OBJECTIVE: We assessed the clinical presentation, operative findings, and surgical treatment outcomes for axillary-subclavian vein (AxSCV) thrombosis due to venous thoracic outlet syndrome (VTOS).

METHODS: We performed a retrospective, single-center review of 266 patients who had undergone primary surgical treatment of VTOS between 2016 and 2022. The clinical outcomes were compared between the patients in four treatment groups determined by intraoperative venography.

RESULTS: Of the 266 patients, 132 were male and 134 were female. All patients had a history of spontaneous arm swelling and idiopathic AxSCV thrombosis, including 25 (9%) with proven pulmonary embolism, at a mean age of 32.1 …

Engagement In Online Communities By New Mothers In Recovery From Opioid Use Disorder, Nicole M. Mattson, Jennifer M. Ohlendorf

College of Nursing Faculty Research and Publications

Purpose:

The purpose of this study was to examine the role of engagement with online communities by women using medication-assisted treatment (MAT) to manage recovery from opioid use disorder (OUD) during pregnancy and the first year after birth.

Study Design and Methods:

Ten participants were identified through purposive sampling for this secondary data analysis as part of a larger grounded theory study about ways women using MAT for recovery from OUD meet the needs of their mother–infant dyad. Inclusion criteria included: English-speaking, 18 years of age or older, living in the United States, within the first year after birth, using …