Digital Commons Network^™

A Novel Therapy For Refractory Cbfa2t3::Glis2-Associated Amkl Using Stro-002 And Plerixafor, Amy Johnson Md, Mba, Alan S. Gamis, Arturo Molina, Soheil Meshinchi, Karen Lewing

Research Days

Background: CBFA2T3::GLIS2-associated AML (CBF/GLIS AML) is an aggressive form of AML often associated with AMKL and recognized by its unique RAM phenotype by flow. It has a very poor prognosis, frequently refractory to standard of care regimens, with extreme marrow localization of leukemic blasts likely mediated by high CXCR4 (CD184) expression. The CBFA2T3::GLIS2 fusion gene is the most common oncogenic transcript in pediatric AMKL and universally results in high expression of FOLR1 surface antigen. STRO-002, an antibody drug conjugate targeting FOLR1, is currently in Phase I clinical trials for adults with refractory ovarian and endometrial malignancies A summary of 17 …

Understanding Home Visitor Attendance At Well Child Checks: A Mixed Methods Study, Rachel Segal, Sommer Rose, Marcia Dutcher, Tyler Myroniuk, Mary Moffatt, James Anderst

Research Days

Background: Early childhood home visiting programs have variable outcomes on child health across models and studies. Given this variability, novel approaches are needed to foster consistent positive outcomes. One approach is attendance of a home visitor (HV) at medical provider well child checks (WCCs) to provide a stronger link between home visiting and the medical home. This process may be assessed in an exploratory study evaluating the qualitative perceptions and initial quantitative effects of the intervention.

Objectives/Goal: Qualitatively explore perspectives of HVs attending WCCs and quantitatively evaluate effects of the practice on (1) family compliance with American Academy of Pediatrics …

Pediatric Educational Outreach To A Community Based Emergency Department: Clinical Management Of The Febrile Infant, Jess Parker, Frances Turcotte Benedict, Emily Hillman, Ryan C. Jacobsen, Ashley K. Sherman, Arjun Sarin

Research Days

Background: Multiple studies have shown variability in the approach to treatment of febrile infants ≤ 60 days of age in community emergency departments (EDs), and the American Academy of Pediatrics (AAP) recently published new guidelines on management of febrile infants. Therefore, an opportunity exists to provide evidence-based recommendations for the care of this patient population to providers in community EDs.

Objectives/Goal: To assess 1) alignment of community ED provider practices with an AAPinformed Clinical practice guideline (CPG) for management of febrile infants ≤ 60 days of age. 2) change in comfort level and degree of alignment after targeted education.

Methods/Design: …

Inpatient Insulin Management For Severe Hypertriglyceridemia In Pediatrics, Erica Wee, Ryan Mcdonough, Matthew M. Feldt

Research Days

Background: Severe hypertriglyceridemia (SHTG) is defined as triglyceride (TG) >= 1000 mg/dL and increases the risk of developing acute pancreatitis. Insulin activates lipoprotein lipase which accelerates chylomicron degradation leading to a rapid decrease in TG levels. There is a paucity of pediatric standard of care for insulin use to treat SHTG.

Objectives/Goal: Our objective was to develop a protocol to standardize SHTG management using insulin infusion and decrease the duration of SHTG resolution while preventing hypoglycemia.

Methods/Design: Endocrinology, Evidence-Based Practice, Hospital Medicine, Critical Care, Gastroenterology, Pharmacy, and Nursing met to develop the protocol. Pediatric and adult literature were reviewed, and …

Socioeconomic Factors And Picu Interventions In High Mortality Risk Asthmatics, Hanh Ho, Paul N. Bauer, Jade B. Tam-Williams

Research Days

Background: Asthma mortality rates are overall lower in children, but studies estimate 5-10% of asthmatics have refractory mortality prone asthma. Asthmatics with repeat pediatric intensive care unit (PICU) admissions are believed to be at high mortality risk with increased health care utilization and socio-economic challenges.

Objectives/Goal: We aim to identify patients with repeat PICU admissions for status asthmaticus and characterize the levels of interventions and socio-economic status.

Methods: A retrospective chart review was done on patients with the following inclusion criteria: age 0- 18, PICU admission between January 2010 to December 2015, and a diagnosis of status asthmaticus on admission. …

Supporting Families Impacted By Adverse Childhood Experiences (Aces), Jennifer Paumen, Laura Plencner, Jacqueline Kitchen

Research Days

Background: Adverse childhood experiences (ACEs) impact a majority of individuals, with approximately two-thirds of adults having experienced 1 or more ACE.1 The health consequences of ACEs are significant, including cardiovascular disease, cancer, autoimmune diseases, and mental illnesses.1 These health impacts can even start as early as childhood, leading to an increased risk of learning and behavioral concerns.2,3 Recent evidence has also identified the impact that parental ACEs may have on parenting and child development,4,5,6 which in turn may lead to an intergenerational transmission of ACEs.4,7 As a nurturing caregiver relationship is key for buffering adversity,2,8 it is imperative to address …

Pediatric Serum-Like Sickness: A Multicenter Analysis, Maya Gibson, Sarah Suppes, Jared Lovins, Emma Monique, Keith Feldman, Jennifer Goldman

Research Days

Background: Serum sickness-like reaction (SSLR) is a type III immune hypersensitivity reaction that presents 5-21 days following exposure to a medication. SSLR has nonspecific symptoms including fever, rash, and joint involvement. There are no standardized diagnostic criteria or treatment for SSLR, making this a challenging diagnosis.

Objectives/Goal: Our objective was to describe pediatric SSLR clinical manifestations, medical encounter types, and treatment strategies.

Methods/Design: A retrospective chart review across 2 freestanding children’s hospitals was used to identify patients 0-21 years of age diagnosed with SSLR by ICD-9/10 codes [T80.69XA, 999.59], SNOMED codes [1782626019, 3293325014], or pharmacovigilance review in the emergency department …

Maternal Effects On Growth, Leila Ikeda

Undergraduate Research and Engagement Symposium

Maternal effects generally refer to the impact that a mother's traits have upon the connection between direct genes of the offspring and the maternal environment provided for the offspring, shaping offspring's growth and development. While direct maternal effects occur through maternal provisioning or behavior, indirect maternal effects occur through transmission of maternal traits to the offspring via their interaction with the environment. Interval mapping revealed several significant QTLs, places where the maternal genome directly affects offspring phenotype, ranging from weeks 1-20, on chromosomes (chrs) 7 and 18 respectively, and other suggestive QTLs on Chrs 1, 3, 4, 6, and 14.

Cooperation: Key To Management Problems, Mel Byers, David L. Groves

Visions in Leisure and Business Monographs

Reprint of a 2001 publication developed for the Toledo Industrial Recreation and Employee Services Association (TIRES).

A Hidden Language, Francesca Yenovkian

Liberty University Research Week

Undergraduate

2-D

The Rowboating Row-Bot In Existential Crisis, Cassandra Poorman

Liberty University Research Week

Undergraduate

3-D

Fearfully And Wonderfully Made, Aunna Leach

Liberty University Research Week

Undergraduate

3-D

This Dance Has No Steps, Aunna Leach

Liberty University Research Week

Undergraduate

3-D

The House Of Our Gods, Reyna Collazo

Liberty University Research Week

Undergraduate

3-D

Impact Of Iot On Consumer Behaviour, Amira Remadna

Management Dynamics

Purpose: The aim of this paper is to provide a deeper understanding of the effects of IoT on consumers’ intentions and behaviours and lay the ground for future research on the perspectives and trends in marketing. Design/methodology/approach – A review of existing literature is applied as the research methodology in addition to retrieving patterns from specialized secondary sources focusing on IoT dimensions and perspectives. Findings – The research findings address insights regarding the potential impact of IoT and its components on the theories of Consumer Behaviour through all its different dimensions. The results provide an extended understanding of the antecedents …

Mitigating The Negative Views Of Customers While The Adoption Of Artificial-Intelligence Chatbots In Online Banking Services: Relevant Gaps And Future Research Agenda, Abdullah Nabeel Al-Roshoud

Management Dynamics

The daily evolvement and growing interest in AI adoption worldwide, within different industrial sectors, have triggered scholars and practitioners to keep looking after every single piece of information and promising ideas that they can beneficially gather relative to that topic for the sake of enhancing consumers' experiences and excitements while using banks' mobile apps or any other online services. The level of adoption for AI chatbots in banking sectors promises to boost the servicing experience. however, due to issues related to trust, privacy, security, and emotional connections, the level of reluctancy while dealing with these AI chatbots still exists with …

Emergent Issues In Cryptocurrency: Identifying Research Gaps And Future Directions, Mohamad Fouad Shorbaji

Management Dynamics

This paper highlights potential research areas that require further investigation, suggesting that there are still significant gaps in the understanding of the factors that drive consumer behavior and adoption in the cryptocurrency industry. The study emphasizes the need for future research to explore issues such as the role of social media, trust, and branding in the cryptocurrency market, and their implications for marketing and business strategies. By identifying these research gaps, the study aims to encourage further exploration of these issues and contribute to a better understanding of the challenges and opportunities presented by this rapidly evolving industry.

Access To Information And Enhanced Reading Culture For Sustainable Economic Development In Nigeria: The Role Of Libraries, Oluwatosin Akobe

Library Philosophy and Practice (e-journal)

The sustainable development goal is a match towards revamping the economy of nations. Nigeria embarks on the journey of economic redemption. It is expected that, as with the sustainable development goals, national governments will develop their own action plans that emphasize or deemphasize various goals depending on the local situation. Be that as it may, a country like Nigeria needs literate citizens, citizens who are ready to commit themselves to the use of libraries, access relevant information and digest this information for the benefit of all and to ensure a steady economic growth hence, the need to promote the reading …

Genome-Wide Association Study Of The Maize Crop By The Lasso Regression Analysis, Amir Alipour Yengejeh

Data Science and Data Mining

The accurate estimation of the male flowering period in Maize crops is key for the prediction crop fertility. The recent scientific investigations has shown that the genetic single nucleotic polymorphism (SNP) can contribute in this regard. The genomewide association study (GWAS) is employed to generate these attributes (SNP). But it caused a high-dimensional data in which 4,981 observations with 7,389 SNP attributes. Hence, in this study, we used the penalized regression approach with the least absolute shrinkage and selection operator (Lasso) to reduce the dataset. In this regard, we set the regularization parameter to 0.21. It resulted in a set …

Analysis Of Credit Approval By Decision Tree, Amir Alipour Yengejeh

Data Science and Data Mining

Nowadays, machine learning algorithms are com-
monly used by the financial institutions or bankers to evaluate
the applications’ requires for credit card. In this study, we used
the decision tree algorithm to predict credit card approval based
on the other associated features applicants like age, employment
status, Education Level, etc. Our results shows that the applicants’
Prior Default and Debt, and Employed have more contribution
in the credit card approval.

Movie Recommender System Using Matrix Factorization, Roland Fiagbe

Data Science and Data Mining

Recommendation systems are a popular and beneficial field that can help people make informed decisions automatically. This technique assists users in selecting relevant information from an overwhelming amount of available data. When it comes to movie recommendations, two common methods are collaborative filtering, which compares similarities between users, and content-based filtering, which takes a user’s specific preferences into account. However, our study focuses on the collaborative filtering approach, specifically matrix factorization. Various similarity metrics are used to identify user similarities for recommendation purposes. Our project aims to predict movie ratings for unwatched movies using the MovieLens rating dataset. We developed …

Improved Face Morphing Attack Detection Method Using Pca And Convolutional Neural Network, Iman S. Razaq, Baheja K. Shukur

Karbala International Journal of Modern Science

Face recognition is the most extensively utilized security and public safety verification method. In many nations, the Automatic Border Control system uses face recognition to confirm the identification of travelers The ABC system is vulnerable to face morphing attacks; the face recognition systems give acceptance for the traveller, even though the passport photo does not represent the actual image of the person but is a result of the merger of two images. Therefore, it is vital to determine whether the passport image is altering (morph) or actual. This research proposes an improved method to extract features from facial images. The …

Secure Qr-Code Generation In Healthcare, Safa S. Abdul-Jabbar, Alaa K. Farhan

Karbala International Journal of Modern Science

QR codes have become ubiquitous across several industries, including e-commerce, education, and healthcare. In the healthcare sector, QR codes are increasingly used to relay essential information regarding medical products, patient history, and healthcare education. In addition, QR codes have proven to help secure and preserve patient records during transmissions. This paper aims to develop and analyze the implementation of QR code technology for healthcare appli-cations. The proposed approach involves generating a unique QR code for each patient's information, facilitating data transmission between nodes such as hospitals. With its small size, the QR code provides a simple solution to transfer patient …

Optical Waveguide Testing System With Standoff, Zhida Xu, Quandou Wang

Defensive Publications Series

A waveguide display test system. The system includes a plurality of projectors, a mounting assembly, and a camera. The mounting assembly is covered to hold a waveguide under test. In an image quality configuration a single projector is used with an optical relay that provides a standoff distanced between a virtual pupil and the single projector, and the virtual pupil is located at a walk off distance from the waveguide. In an modulation transfer function (MTF) tester configuration, the single projector is replaced with a plurality of projectors. And each of the plurality of projectors includes a respective relay system …

G-Coatomic Modules, Ahmed H. Alwan

Al-Bahir

Let R be a ring and M be a right R-module. A submodule of is said to be g-small in , if for every submodule , with implies that . Then is a g-small submodule of . We call g-coatomic module whenever and then . Also, is called right (left) g-coatomic ring if the right (left) -module (R) is g-coatomic. In this work, we study g-coatomic modules and ring. We investigate some properties of these modules. We prove is g-coatomic if and only if each is g-coatomic. It is proved that if is a g-semiperfect ring with , then …

Comparison Between Honey Produced By Bees, Aphids And Wasps In Kurdistan Region - Iraq Based On Biochemical Parameters, Jian Lateif Hussein

Al-Bahir

Honey is a sweet substance that has been valued by humans for its taste and health benefits. It is produced by honey bees from the sugary secretions of plants. However, other insects, such as aphids and wasps, also produce honey-like substances. This study aimed to compare the physical and biochemical properties of honey produced by honey bees, aphids, and wasps in the Kurdistan Region of Iraq. To achieve this, samples of honey, bitter honey, honeydew, and wasp honey were collected and examined. The samples were analyzed for total sugar, sucrose, water, Hydroxymethylfurfural (HMF), acidity, total acidity, diastase activity, total phenolic …

Epidemiological Distribution Of Primary Salivary Gland Tumors. Retrospective Analysis In Baghdad Medical City, Osama Mohammed Ghazi

Maaen Journal for Medical Sciences

Background: Studies on the incidence of salivary tumors around the world showed variations, including in Iraq. This study was intended to evaluate the relative incidence of these tumors among the Iraqi population. Materials and methods: The current retrospective study encompassed 109 cases retrieved from the file records of the pathology laboratory of Baghdad Medical City over a five-year period from January 2017 to December 2021. Information regarding age, gender, site, and tumor type was assembled and analyzed using a statistical package for social sciences (SPSS version 20). Results: The present study documented that salivary gland tumors represent 1.35% of the …

Three Essays On New Issues In Corporate Finance, Abdullah Shoeb

Theses and Dissertations

This dissertation focuses on three new issues in corporate finance, each aiming at different aspects of a firm's behavior. First, I propose a novel way to classify domestic manufacturing firms based on their level of financial constraint. Using the operating cash flow ratio as my new measure, I find that the behavior of constrained and unconstrained firms differ significantly, unlike existing constraint measures from the literature. My results indicate that constrained firms cannot engage in equity recycling, have a higher sensitivity to cash flow, use the proceeds from the sales of their fixed assets in R&D, and cannot change leverage …

Library Noets & Quotes, V1i3, Ctr Library Faculty & Staff, Lindsay Brownfield

Library Notes and Quotes

Contents:

• A Note From the Dean
• How to Find Us
• Art Corner
• Summer Reads by Staff
• From the Stacks
• "What are you reading now?

Advancing College Food Security: Priority Research Gaps, Matthew J. Landry, Emily Heying, Zubaida Qamar, Rebecca L. Hagedorn-Hatfield, Mateja R. Savoie-Roskos, Cara L. Cuite, Victoria A. Zigmont, Kendra Oonorasak, Susan Chen

Nutrition Faculty Publications

Despite over a decade of both quantitative and qualitative studies, food insecurity among US college/university students remains a pervasive problem within higher education. The purpose of this perspective piece was to highlight research gaps in the area of college food insecurity and provide rationale for the research community to focus on these gaps going forward. A group of food insecurity researchers from a variety of higher education institutions across the United States identified five thematic areas of research gaps: screening and estimates of food insecurity; longitudinal changes in food insecurity; impact of food insecurity on broader health and academic outcomes; …