Digital Commons Network^™

The Struggles Of Online Teaching: Strategies To Improve Online Teaching, Maria Zaman

CEHD Annual Research Conference

The poster emphasizes the difficulty of online teaching, especially for first-time teachers, who may feel lost or overwhelmed by the content. The poster also aims to demonstrate that these struggles are common and that other teachers have found ways to improve their online teaching experience.

Experiences And Perceptions Of The Supervisory Relationship In Bipoc Health Service Psychology Dyads, Anna K. Nguyen, Genel Gronkowski, Andrew C. Lenway, Topaza Yu, Rachel L. Navarro

CEHD Annual Research Conference

No abstract provided.

Teaching Digital Citizenship And Social Emotion Learning Together: A Comprehensive Literature Review, Jill K. Baird

CEHD Annual Research Conference

No abstract provided.

An Introduction To The Bartik Benefit-Cost Model Of Business Incentives, Timothy J. Bartik

Reports

This short report provides an introduction to a new model of the benefits and costs of business incentives to promote state economic development. This model provides potential users—anyone interested in evaluating an incentive project or incentive program in their state—with a model that can be used for practical evaluation purposes, such as deciding whether or not a project should be undertaken, whether or not to expand or terminate a current incentive program, or how an incentive program could be improved by reforms to have higher net benefits. What is most distinctive about the model is that it focuses on how …

Association Of Brain Age, Lesion Volume, And Functional Outcome In Patients With Stroke, Sook-Lei Liew, Nicolas Schweighofer, James H. Cole, Artemis Zavaliangos-Petropulu, Bethany P. Lo, Laura K.M. Han, Tim Hahn, Lianne Schmaal, Miranda R. Donnelly, Jessica N. Jeong, Zhizhuo Wang, Aisha Abdullah, Jun H. Kim, Alexandre Hutton, Giuseppe Barisano, Michael R. Borich, Lara A. Boyd, Amy Brodtmann, Cathrin M. Buetefisch, Winston D. Byblow, Jessica M. Cassidy, Charalambos C. Charalambous, Valentina Ciullo, Adriana Bastos Conforto, Rosalia Dacosta-Aguayo, Julie A. Dicarlo, Martin Domin, Adrienne N. Dula, Natalia Egorova-Brumley, Wuwei Feng, Fatemeh Geranmayeh, Chris M. Gregory, Colleen A. Hanlon, Kathryn Hayward, Jess A. Holguin, Brenton Hordacre, Neda Jahanshad, Steven A. Kautz, Mohamed Salah Khlif, Hosung Kim, Amy Kuceyeski, David J. Lin, Jingchun Liu, Martin Lotze, Bradley J. Macintosh, John L. Margetis, Maria Mataro, Feroze B. Mohamed, Emily R. Olafson, Gilsoon Park, Fabrizio Piras, Kate P. Revill, Pamela Roberts, Andrew D. Robertson, Nerses Sanossian, Heidi M. Schambra, Na Jin Seo, Surjo R. Soekadar, Gianfranco Spalletta, Cathy M. Stinear, Myriam Taga, Wai Kwong Tang, Greg T. Thielman, Daniela Vecchio, Nick S. Ward, Lars T. Westlye, Carolee J. Winstein, George F. Wittenberg, Steven L. Wolf, Kristin A. Wong, Chunshui Yu, Steven C. Cramer, Paul M. Thompson

Department of Neurology Faculty Papers

BACKGROUND AND OBJECTIVES: Functional outcomes after stroke are strongly related to focal injury measures. However, the role of global brain health is less clear. In this study, we examined the impact of brain age, a measure of neurobiological aging derived from whole-brain structural neuroimaging, on poststroke outcomes, with a focus on sensorimotor performance. We hypothesized that more lesion damage would result in older brain age, which would in turn be associated with poorer outcomes. Related, we expected that brain age would mediate the relationship between lesion damage and outcomes. Finally, we hypothesized that structural brain resilience, which we define in …

From Bugs To Drugs: Bacterial 3-Iaa Enhances Efficacy Of Chemotherapy In Pancreatic Cancer, Y David Seo, Jennifer A Wargo

Faculty, Staff and Student Publications

Tintelnot et al. identified enrichment of indole-3-acetic acid (3-IAA), a tryptophan metabolite produced by gut microbiota, as a predictor of chemotherapy response in pancreatic adenocarcinoma. Recapitulated in mouse models, 3-IAA represents a novel potential therapeutic approach for chemotherapy sensitization.

Evaluation Of 89zr-Labeled Anti-Pd-L1 Monoclonal Antibodies Using Dfo And Novel Hopo Analogues As Chelating Agents For Immuno-Pet, Bhasker Radaram, Sarah E Glazer, Ping Yang, Chia-Wei Li, Mien-Chie Hung, Seth T Gammon, Mian Alauddin, David Piwnica-Worms

Faculty, Staff and Student Publications

Programmed death ligand 1 (PD-L1) is a type 1 transmembrane immunosuppressive protein that is expressed on a wide range of cell types, including cancer cells. Anti-PD-L1 antibodies have revolutionized cancer therapy and have led to improved outcomes for subsets of cancer patients, including triple-negative breast cancer (TNBC) patients. As a result, PET imaging of PD-L1 protein expression in cancer patients has been explored for noninvasive detection of PD-L1 expressing tumors as well as monitoring response to anti-PD-L1 immune checkpoint therapy. Previous studies have indicated that the in vivo stability and in vivo target detection of antibody-based radio-conjugates can be dramatically …

Simulating Electrified Powertrain Noise And Vibration Measurement Signals For Machine Learning Based Fault Diagnosis Applications, Joohyun Lee, Yangfan Liu, J Stuart Bolton, Patricia Davies

Publications of the Ray W. Herrick Laboratories

Machine learning classification is a common method for vehicle noise and vibration (N&V) fault diagnosis which helps improve vehicle safety, comfort, and reduce maintenance cost. To improve the accuracy of classification, the model requires sufficient training data which is often expensive and time-consuming to acquire. A possible solution to resolve this limitation is to extract representative features from measurement signals and generate realistic simulated signals based on a smaller set of high-quality N&V measurement signals. A method to simulate N&V measurement signals of rotating machineries such as electrified powertrains is proposed. In its feature extraction process, tonal and broadband components …

Leveraging Mathematical Modeling To Analyze Nonadherence For Hydroxyurea Therapy In Sickle Cell Disease, Akancha Pandey, Rubesh Raja, Jeremie H. Estepp, Doraiswami Ramkrishna

Purdue University Libraries Open Access Publishing Fund

Nonadherence is common in individuals with sickle cell disease (SCD) on hydroxyurea therapy and can be observed with waning improvements in hematologic parameters or biomarkers like mean cell volume and fetal hemoglobin level over time. We modeled the impact of hydroxyurea nonadherence on longitudinal biomarker profiles. We estimated the potential nonadherent days in individuals exhibiting a drop in biomarker levels by modifying the dosing profile using a probabilistic approach. Incorporating additional nonadherence using our approach besides existing ones in the dosing profile improves the model fits. We also studied how different patterns in adherence give rise to various physiological profiles …

Frequency Reduction And Attenuation Of The Tire Air Cavity Mode Due To A Porous Lining, Kyosung Choo, Won Hong Choi, Guochenhao Song, J Stuart Bolton

Publications of the Ray W. Herrick Laboratories

The tire air cavity mode is known to be a significant source of vehicle structure-borne road noise near 200 Hz. A porous lining placed on the inner surface of a tire is an effective countermeasure to attenuate that resonance. The two noticeable effects of such a lining are the reduction in the cavity resonance frequency and the attenuation of the air cavity mode. In this paper, through both theoretical and numerical analysis, the mechanisms underlyiing the effects of a porous lining were studied. A two-dimensional duct-shaped theoretical model and a torus-shaped numerical model were created to investigate the lined tire …

A Transfer-Matrix-Based Approach To Predicting Acoustic Properties Of A Layered System In A General, Efficient, And Stable Way, Guochenhao Song, Zhuang Mo, J Stuart Bolton

Publications of the Ray W. Herrick Laboratories

Layered materials are one of the most commonly used acoustical treatments in the automotive industry, and have gained increased attention, especially owing to the popularity of electric vehicles. Here, a method to model and couple layered systems with various layer types (i.e., poro-elastic layers, solid-elastic layers, stiff panels, and fluid layers) is derived that makes it possible to stably predict their acoustical properties. In contrast with most existing methods, in which an equation system is constructed for the whole structure, the present method involves only the topmost layer and its boundary conditions at two interfaces at a time, which are …

Force Amplification At The Wheel Hub Due To The Split In The Air-Cavity Mode For A Rolling Tire, Won Hong Choi, Kyosung Choo, J Stuart Bolton

Publications of the Ray W. Herrick Laboratories

Reduction of tire/road noise has become an important issue for EVs since powertrain noise has largely been eliminated. A tire’s air-cavity mode is known to be a significant contributor to increased forces at the wheel hub, which can result in significant interior noise levels near 200 Hz. Moreover, the single natural frequency of a static, undeformed tire can separate into two neighboring frequencies for a rolling, deformed tire due to the combination of the tire’s asymmetry, and the Doppler effect resulting from the tire’s rotation. In this study, the evolution of the Doppler-related frequency split with increasing speed was observed …

Downstream Effects: Impact Of Antibiotic Pollution On An Aquatic Host-Parasite Interaction, Hannah G. Melchiorre, Stephanie O. Gutierrez, Dennis J. Minchella, Jing Trevor Vannatta

Purdue University Libraries Open Access Publishing Fund

The global increase in antibiotic use has led to contamination of freshwater environments. Despite the identified impacts of antibiotics on humans and wildlife, the effect of antibiotics on host–parasite life cycles in freshwater is relatively unexplored. In the current study, we utilize the trematode parasite Schistosoma mansoni, and its snail intermediate host, Biomphalaria glabrata, to investigate the influence of an ecologically relevant antibiotic concentration on the life history characteristics of both parasite and host. Our results demonstrate that antibiotics not only accelerate parasite development time, but also increase host reproduction and delay parasite-induced host castration. Using a mathematical …

Data Collection Research For Multidisciplinary Design & Prototyping Fall 2023: Spring 2023 Mems 400 Independent Study, Hayato Takai, Julian Wu

Mechanical Engineering and Materials Science Independent Study

Dr. Jackson Potter is a Mechanical Engineer and professor at Washington University in St. Louis. One of the classes he teaches is called Multidisciplinary Design & Prototyping (MEMS 312). The class is taken by students from various disciplines to learn about design processes and develop new skills. In addition, this class typically has a theme to make the prototyping process more realistic and have an end goal. For 2022 the theme was accessible gaming, where students would create universal gaming controllers for people that might not be able to use traditional controllers. For the next year, Dr. Potter wanted to …

Micro-Tug Device Fabrication As Platform For 3d Tissue Dynamical Construction And Magnetic Actuation, Zhuangyu Zhang

Mechanical Engineering and Materials Science Independent Study

This study presents the development of a micro-tug tissue platform aimed at improving the study of tissue morphogenesis. The research focused on fabricating high-throughput devices for tissue construction and integrating magnetically responsive particles to control stress and manipulate tissue morphogenesis. The devices enable the simulation of various mechanical environments, such as hypertension in cardiomyocytes. We successfully fabricated Polydimethylsiloxane (PDMS) micro-tug devices and their iron-containing variants, along with a magnetic field-generating device to apply variable mechanical stresses. The fabrication process transitioned from a time-consuming hydrogel casting method to a more efficient system using 3D print models and surface chemistry on PDMS …

Targeting The Warburg And Q Effect: Novel Strategy To Disrupt Cancer Metabolism, Mahmoud Adel Mohamed

Theses and Dissertations

One of the hallmarks of cancer cells is their altered metabolism, which serves their need to grow and proliferate. Cancer cells exhibit a marked increase in glucose consumption (Warburg effect). In addition, cancer cells also exhibit excessive uptake of glutamine, for biomass synthesis and for energy production through mitochondrial substrate level phosphorylation (glutaminolysis pathway). Glutamine metabolism is enhanced upon inhibition of glycolysis, also interference of glutamic metabolism leads to upregulation of glucose metabolism. So, simultaneous inhibition of glycolysis and glutaminolysis presents promising metabolic intervention strategy. In this study, we investigated high dose Vitamin C mechanism of action through MTT assays …

Supervised Deep Learning With Vision Transformer Predicts Delirium Using Limited Lead Eeg, Malissa A. Mulkey Phd, Aprn, Ccns, Ccrn, Cnrn, Huyunting Huang, Thomas Albanese, Sunghan Kim, Baijian Yang Ph.D.

Publications

UNLABELLED: Critically ill patients with COVID-19 experience high rates of delirium and coma. Whether delirium occurs through novel mechanisms in COVID-19 is not known. We analyzed the relationship among biomarkers of inflammation (C-reactive protein [CRP]), hypercoagulability (d-dimer), and lung macrophage activation (ferritin), and the primary composite outcome of delirium/coma next day. We also measured associations between biomarkers and next day delirium and coma independently, and delirium severity. DESIGN: Retrospective, observational cohort study. SETTING: ICUs at two large, urban, academic referral hospitals. PATIENTS: All consecutive adult patients admitted to the ICU from March 1, 2020, to June 7, 2020, with COVID-19 …

A Hörmander–Fock Space, Daniel Alpay, Fabrizio Colombo, Kamal Diki, Irene Sabadini, Daniele C. Struppa

Mathematics, Physics, and Computer Science Faculty Articles and Research

In a recent paper we used a basic decomposition property of polyanalytic functions of order 2 in one complex variable to characterize solutions of the classical ∂-problem for given analytic and polyanalytic data. Our approach suggested the study of a special reproducing kernel Hilbert space that we call the Hörmander-Fock space that will be further investigated in this paper. The main properties of this space are encoded in a specific moment sequence denoted by η= (η_n)_n≥0 leading to a special entire function E(z) that is used to express the kernel function of the Hörmander-Fock space. We …

Ecological Boundaries And Constraints On Viable Eco-Evolutionary Pathways, Kyle E. Coblentz, John P. Delong

School of Biological Sciences: Faculty Publications

Evolutionary dynamics are subject to constraints ranging from limitations on what is physically possible to limitations on the pathways that evolution can take. One set of evolutionary constraints, known as ‘demographic constraints’, constrain what can occur evolutionarily due to the demographic or dynamical consequences of evolution leading to conditions that make populations susceptible to extinction. These demographic constraints can limit the strength of selection or the rates of environmental change populations can experience while remaining extant and the trait values a population can express. Here we further hypothesize that the population demographic and dynamic consequences of evolution also can constrain …

Lesmha Lp V. Vasquez

All Decisions

The landlord sought to evict the tenant through a holdover proceeding, claiming the tenant was a licensee who refused to sign a new lease. The tenant argued a valid 99-year lease existed with rent based on income, protected under the Rent Stabilization Law. The court denied the landlord's motion to dismiss the tenant's defenses and counterclaims, finding factual issues regarding the lease terms and rent calculation that precluded summary judgment for the landlord. The court also severed the tenant's request for attorney's fees from the case.

Real-Time Suitable Predictive Control Using Spat Information From Automated Traffic Lights, Pradeep Bhat, Bo Chen

Michigan Tech Publications

Traffic intersections throughout the United States combine fixed, semi-actuated, and fully actuated intersections. In the case of the semi-actuated and actuated intersections, uncertainties are considered in phase duration. These uncertainties are due to car waiting queues and pedestrian crossing. Intelligent transportation systems deployed in traffic infrastructure can communicate Signal and Phase Timing messages (SPaT) to vehicles approaching intersections. In the connected and automated vehicle ecosystem, the fuel savings potential has been explored. Prior studies have predominantly focused on fixed time control for the driver. However, in the case of actuated signals, there is a different and significant challenge due to …

New Research Into Potential Impacts Of Beech Leaf Disease (Bld) To Begin At Unh, Nicholas Gosling

UNH Today Archive

No abstract provided.

Low Educational Attainment Is Associated With Higher All-Cause And Cardiovascular Mortality In The United States Adult Population, Najah Khan, Zulqarnain Javed, Isaac Acquah, Kobina Hagan, Madiha Khan, Javier Valero-Elizondo, Ryan Chang, Umair Javed, Mohamad B. Taha, Salim S. Virani

Office of the Provost

Introduction: Educational attainment is an important social determinant of health (SDOH) for cardiovascular disease (CVD). However, the association between educational attainment and all-cause and CVD mortality has not been longitudinally evaluated on a population-level in the US, especially in individuals with atherosclerotic cardiovascular disease (ASCVD). In this nationally representative study, we assessed the association between educational attainment and the risk of all-cause and cardiovascular (CVD) mortality in the general adult population and in adults with ASCVD in the US.
Methods: We used data from the 2006-2014 National Death Index-linked National Health Interview Survey for adults ≥ 18 years. We generated …

Gata Now!, Georgia Southern University

Athletics: News & Publications

No abstract provided.

Book Review: The Strategic Use Of Force In Counterinsurgency: Find, Fix, Fight, José De Arimatéia Da Cruz

Parameters Bookshelf – Online Book Reviews

Author: Miles Kitts

Reviewed by Dr. José de Arimatéia da Cruz, professor of international relations and comparative politics, Georgia Southern University, and visiting professor, Center for Strategic Leadership, US Army War College

Focusing on the use of force and insurgency, the reviewer assesses the author’s question, “Does either neoclassicism or revisionism adequately address how to evaluate the utility of force in counterinsurgency and the prescriptions which should come from it?”

Volume 121, Number 1 - Tuesday, May 16th, 2023, Saint Mary's College Of California

The Collegian

No abstract provided.

How Does Facilitation In Healthcare Work? Using Mechanism Mapping To Illuminate The Black Box Of A Meta-Implementation Strategy, Amy M Kilbourne, Elvin Geng, Ingrid Eshun-Wilson, Shannon Sweeney, Donna Shelley, Deborah J Cohen, Joann E Kirchner, Maria E Fernandez, Michael L Parchman

Faculty, Staff and Student Publications

BACKGROUND: Healthcare facilitation, an implementation strategy designed to improve the uptake of effective clinical innovations in routine practice, has produced promising yet mixed results in randomized implementation trials and has not been fully researched across different contexts.

OBJECTIVE: Using mechanism mapping, which applies directed acyclic graphs that decompose an effect of interest into hypothesized causal steps and mechanisms, we propose a more concrete description of how healthcare facilitation works to inform its further study as a meta-implementation strategy.

METHODS: Using a modified Delphi consensus process, co-authors developed the mechanistic map based on a three-step process. First, they developed an initial …

How Does Facilitation In Healthcare Work? Using Mechanism Mapping To Illuminate The Black Box Of A Meta-Implementation Strategy, Amy M Kilbourne, Elvin Geng, Ingrid Eshun-Wilson, Shannon Sweeney, Donna Shelley, Deborah J Cohen, Joann E Kirchner, Maria E Fernandez, Michael L Parchman

Faculty, Staff and Student Publications

BACKGROUND: Healthcare facilitation, an implementation strategy designed to improve the uptake of effective clinical innovations in routine practice, has produced promising yet mixed results in randomized implementation trials and has not been fully researched across different contexts.

OBJECTIVE: Using mechanism mapping, which applies directed acyclic graphs that decompose an effect of interest into hypothesized causal steps and mechanisms, we propose a more concrete description of how healthcare facilitation works to inform its further study as a meta-implementation strategy.

METHODS: Using a modified Delphi consensus process, co-authors developed the mechanistic map based on a three-step process. First, they developed an initial …

Evaluation Of Temperature-Index And Energy-Balance Snow Models For Hydrological Applications In Operational Water Supply Forecasts, Tian Gan, David G. Tarboton, Tseganeh Z. Gichamo

Civil and Environmental Engineering Faculty Publications

In the western United States, snow accumulation, storage, and ablation affect seasonal runoff. Thus, the prediction of snowmelt is essential to improve the reliability of water supply forecasts to guide water allocation and operational decisions. The current method used at the Colorado Basin River Forecast Center (CBRFC) couples the SNOW-17 temperature index snow model and the Sacramento Soil Moisture Accounting (SAC-SMA) runoff model in a lumped approach. Limitations in parameter transferability and calibration requirements for changing conditions with the temperature-index model motivated this research, in which new avenues were investigated to assess and prototype the application of an energy-balance snow …

Research Routes On Awake Bruxism Metrics: Implications Of The Updated Bruxism Definition And Evaluation Strategies., Alessandro Bracci, Frank Lobbezoo, Anna Colonna, Steven Bender, Paulo C. R. Conti, Alona Emodi‐Perlman, Birgitta Häggman‐Henrikson, Gary D. Klasser, Ambra Michelotti, Gilles J. Lavigne, Peter Svensson, Jari Ahlberg, Daniele Manfredini

School of Dentistry Faculty Publications

Background: With time, due to the poor knowledge on it epidemiology, the need to focus on awake bruxism as a complement of sleep studies emerged. Objective: In line with a similar recent proposal for sleep bruxism (SB), defining clinically oriented research routes to implement knowledge on awake bruxism (AB) metrics is important for an enhanced comprehension of the full bruxism spectrum, that is better assessment and more efficient management. Methods: We summarised current strategies for AB assessment and proposed a research route for improving its metrics. Results: Most of the literature focuses on bruxism in general or SB in particular, …