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Information Technology News, Georgia Southern University

Information Technology: News & Publications (2012-2023)

• Georgia Southern Redesignated as a National Security Agency Center of Academic Excellence inCyber Defense
• Assistant Professor Frank Katz Presents at NSA-CAE Symposium in Seattle

Optimizing The Membrane-Assisted Recovery Of Solids (Mars) Technology For Nutrient Removal And Recovery From Concentrated Waste Streams, Ben Yamin Hoque

USF Tampa Graduate Theses and Dissertations

The effective management of nutrients, such as nitrogen and phosphorus, in decentralizedwastewater treatment environments is a pressing challenge. These nutrients pose significant risks to the environment and public health when discharged into water bodies, while their recovery and reuse can help alleviate nutrient shortages in various industries, including agriculture. Conventional biological treatment methods used in centralized facilities are not suitable for decentralized systems due to operational complexities and space limitations. Chemical treatment mechanisms, such as adsorption, ion exchange, precipitation, and air-stripping, offer potential solutions but are accompanied by challenges like high costs and logistical issues. Therefore, finding a sustainable and …

Defining A Factor-Induced Signaling Signature For Endothelial Tubulogenesis, Sprouting, And Pericyte Recruitment, Prisca Kuanting Lin

USF Tampa Graduate Theses and Dissertations

Endothelial cells (ECs) form the inner lining of blood capillary walls. Our laboratory has developed a serum-free, defined Factor system that allows for human ECs to sprout, form lumens and tube networks, recruit pericytes, and induce capillary basement membrane deposition in 3D extracellular matrices. We have shown that the Factor system drives morphogenesis through the activation of multiple signaling pathways; however, we do not know if all factors in the Factor system are needed to induce maximal EC morphogenesis. If so, we have yet to identify why the Factors are critical to the model other than that they induce activation …

Butte Priority Soils Operable Unit (Bpsou) Field Xrf To Laboratory Correlation And Regression Analysis Procedure For Unreclaimed (Ur) And Insufficiently Reclaimed (Ir) Sites, Mike Mcanulty, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Information Technology News, Georgia Southern University

Computing: News & Publications (2012-2023)

• Georgia Southern Redesignated as a National Security Agency Center of Academic Excellence inCyber Defense
• Assistant Professor Frank Katz Presents at NSA-CAE Symposium in Seattle

A Strong And Ductile Cobalt-Free Solid-Solution Fe30ni30mn30cr10 Multi-Principal Element Alloy From Hot Rolling, Hans Pommerenke, Jiaqi Duan, Nathan Curtis, Victor Delibera, Adam Bratten, Andrew Hoffman, Mario Buchely, Ronald O'Malley, Haiming Wen

Materials Science and Engineering Faculty Research & Creative Works

Most of the face-centered cubic (FCC) multi-principal element alloys (MPEAs) developed thus far contain cobalt. for many applications, it is either required or beneficial to avoid cobalt, since cobalt has long-term activation issue (for nuclear applications), is expensive, and is considered a critical material. in addition, FCC structured solid-solution MPEAs tend to have relatively low strength. an FCC solid-solution Fe30Ni30Mn30Cr10 (at %) MPEA was fabricated via arc melting, followed by homogenization at 1100 °C for 12 h. the alloy was hot rolled at 1100 °C with a total reduction of up to 97 %. the microstructure was characterized, and mechanical …

The Association Between Reintegration, Perceptions Of Health And Flourishing During Transition From Military To Civilian Life Among Veterans With Invisible Injuries, Nicholas Rattray, Mindy Flanagan, Michelle Salyers, Diana Natividad, Ai-Nghia Do, Richard Frankel, Katrina Spontak, Marina Kukla

Health Services and Informatics Research

Veterans with mental health or cognitive conditions who are separating from military service often face challenges transitioning to civilian life. However, questions remain about the relationship between reintegration and key psychosocial and well-being outcomes for veteran populations with invisible injuries soon after military separation. We investigated cross-sectional relationships between reintegration difficulties and health and well-being outcomes based on data from standardized measures with 75 US veterans. Reintegration difficulties were associated with low mental health functioning, lower social support, and lower flourishing. Reporting fewer perceived limitations with reintegration was positively associated with physical functioning, and higher levels of participation were positively …

Elementary Teachers' Perspectives On Teaching Reading Comprehension, Reid Smith, Pamela Snow, Tanya Serry, Lorraine Hammond

Research outputs 2022 to 2026

PURPOSE: We report findings from a survey of elementary teachers regarding reading instruction. The purpose was to examine teachers' beliefs about how children in the first 7 years of schooling develop reading comprehension skills and to characterize the self-reported practices and strategies they use to support children to comprehend connected text. METHOD: A web-based survey was used to collect data from 284 Australian elementary teachers about their beliefs and practices regarding reading comprehension instruction. Selected Likert-scale items were aggregated to determine the degree to which participants held "child-centered" or "content-centered" views of reading instruction. RESULTS: Australian elementary school teachers hold …

Message From The President, Georgia Southern University

Messages from the President

• July 5, 2023 – Summer Updates

Office Of Research, Economic Engagement And Outreach Update, July 5, 2023, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

“An All-Inclusive, User-Friendly Resource”: A Review Of Taylor, Bogdan, And Devault’S Introduction To Qualitative Research Methods: A Guidebook And Resource (4th Edition), Mohammed Worku, Haymanot Alemayehu, Leta Ashebir, Kenenisa Lemi Debela Dr.

The Qualitative Report

We reviewed Taylor, Bogdan, and DeVault’s book entitled, Introduction to Qualitative Research Methods: A Guidebook and Resource (4th ed., 2016), and found to be an all-inclusive guide, user-friendly, and resourceful for qualitative researchers. Its inclusion of selected studies as examples to align them with the narratives of the main body of the study makes its value greater.

Patient's Perspective Of Shared Decision-Making In Rheumatoid Arthritis Treatment: A Grounded Theory Exploration, Isabela Viana Oliveira, Mariana Martins Gonzaga Nascimento, Cristiane P. Rezende Mrs, Carina M. Neves, Hagabo Mathyell Silva, Ana Luiza Mourawad Cesar, Djenane Ramalho De Oliveira

The Qualitative Report

Current guidelines for rheumatoid arthritis (RA) treatment state that all decisions should be shared with the patient. Therefore, it becomes necessary to understand in-depth how patients with RA with different levels of health literacy and activation feel about sharing the decision with the health professional and how they experience this process. Grounded theory was used. Data collection included semi-structured interviews with 14 patients with RA. From the analysis of the patients’ narratives, four categories were built: “Accepting the changes: non-shared decisions”; “The patient's rationale: why not share?”; “Reaching the requirements for sharing the decision: expanding the patient’s autonomy"; and "Experiencing …

The Strategies Of Post-Covid Age In Iranian Higher Education: A Qualitative Approach, Esmaiel Jafari

The Qualitative Report

In the present study, the strategies of Iranian Higher Education Institutions (HEIs) in the post-COVID era have been considered. The research approach is qualitative and phenomenological, and accordingly, semi-structured interviews were conducted with 19 samples from two groups of chief executive officer and faculty members. Thematic content analysis method was used to analyze the qualitative data. The results showed that the strategies and guidelines of the higher education system in the post-COVID era include (1) Facilitate and promote domestic and international cooperation, (2) Attracting public support (3) Use of various teaching methods and (4) Develop the competencies of the faculty …

Infusing Military Culture In Multicultural Counseling Frameworks: A Phenomenological Study, Katherine M. Atkins, Toni R. Tollerud, Tilottama Roy-White, Lauren E. Brdecka, Deanna Chrones

The Qualitative Report

This descriptive phenomenological study focused on counselor educators’ (CESs) experiences infusing military culture into counseling curriculum. Specifically, this study sought to learn what counseling programs can do to best prepare counselors-in-training to work with military families. The researchers used the McCracken (1988) method to interview ten participants who had terminal degrees in counselor education or a highly related field, experience providing services to military-connected clients, and were aware of military cultural facets (e.g., implicit and explicit expectations, rules, and ways of being). The findings support the need to redefine multiculturalism and intentional infusion of military culture in counseling curriculum to …

Unexpected Sound Omissions Are Signaled In Human Posterior Superior Temporal Gyrus: An Intracranial Study, Hohyun Cho, Yvonne M Fonken, Markus Adamek, Richard Jimenez, Jack J Lin, Gerwin Schalk, Robert T Knight, Peter Brunner

2020-Current year OA Pubs

Context modulates sensory neural activations enhancing perceptual and behavioral performance and reducing prediction errors. However, the mechanism of when and where these high-level expectations act on sensory processing is unclear. Here, we isolate the effect of expectation absent of any auditory evoked activity by assessing the response to omitted expected sounds. Electrocorticographic signals were recorded directly from subdural electrode grids placed over the superior temporal gyrus (STG). Subjects listened to a predictable sequence of syllables, with some infrequently omitted. We found high-frequency band activity (HFA, 70-170 Hz) in response to omissions, which overlapped with a posterior subset of auditory-active electrodes …

An Immunostimulatory Glycolipid That Blocks Sars-Cov-2, Rsv, And Influenza Infections In Vivo, Moriya Tsuji, Zhenlu Chong, Tamarand L Darling, Kuljeet Seehra, Adrianus C M Boon, Michael S Diamond, Et Al.

2020-Current year OA Pubs

Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but emergence of viral variants that are antigenically distinct from the vaccine strains are of concern and additional, broadly acting preventive approaches are desirable. Here, we report on a glycolipid termed 7DW8-5 that exploits the host innate immune system to enable rapid control of viral infections in vivo. This glycolipid binds to CD1d on antigen-presenting cells and thereby stimulates NKT cells to release a cascade of cytokines and chemokines. The intranasal administration of 7DW8-5 prior to virus exposure significantly blocked infection by three different authentic variants of SARS-CoV-2, as …

Evaluating The Generalizability Of Predictive Classifiers Built From Desi Imaging Lipid Data Across Mass Spectrometry Platformsjournal Of The American Society For Mass Spectrometry, Roy Martin, James Suliburk, Livia S Eberlin

Faculty, Staff and Students Publications

In this study, we evaluate the generalizability of predictive classifiers built from DESI lipid data for thyroid fine needle aspiration (FNA) biopsy analysis and classification using two high-performance mass spectrometers (time-of-flight and orbitrap) suited with different DESI imaging sources operated by different users. The molecular profiles obtained from thyroid samples with the different platforms presented similar trends, although specific differences in ion abundances were observed. When using a previously published statistical model built to discriminate thyroid cancer from benign thyroid tissues to predict on a new independent data set obtained, agreement for 24 of the 30 samples across the imaging …

Experimental Investigation Of Polymer Injection In High Permeability Conduits For Material Sustainability And Behavior In Oil Reservoirs, Sherif Fakher, Abdelaziz Lafi Khlaifat

Faculty Journal Articles

No abstract provided.

Prevalence, Severity, And Risk Factors Of Delirium In Critically Ill Stroke Patients, Thomas Lawson

Sigma Foundation for Nursing Research Grant Reports

To determine the prevalence and severity of delirium among adults admitted to a neurocritical care unit who are diagnosed with acute ischemic stroke, intracerebral hemorrhage, and aneurysmal subarachnoid hemorrhage and to determine which predisposing and precipitating factors are associated with developing delirium in the neurocritical care unit among adults admitted with acute ischemic stroke, intracerebral hemorrhage, and aneurysmal subarachnoid hemorrhage.

Brain Structure Correlates Of Obsessive-Compulsive Personality Traits, Allison Moreau

Arts & Sciences Graduate Student Theses and Dissertations

Obsessive-Compulsive Personality Disorder (OCPD) is the most common personality disorder, yet much remains unknown about its etiology. Although neural contributions to many other psychiatric disorders have been extensively studied, few existing studies have examined neural correlates of OCPD. Furthermore, all have had insufficient sample sizes to produce reliable results. Large samples are needed to reliably detect the expected small brain-behavior relationships. However, large neuroimaging studies often do not assess for personality disorders, although many assess for normative personality. The present study employed a Five-Factor Model of personality disorders, which conceptualizes personality disorders as maladaptive extremes of normative personality traits, to …

Investigating Cassava Susceptibility To Xanthomonas Induced Bacterial Blight Using Disease Phenotyping And Genome Engineering Strategies, Kiona Rajene Elliott

Arts & Sciences Graduate Student Theses and Dissertations

In nature, plants regularly contend with bacterial, viral, and fungal pathogens, which employ strategies that promote pathogen fitness and subsequently elicit disease in the host. Xanthomonads are a group of bacterial phytopathogens that induce disease in an extensive range of host plants. Mechanisms underlying pathogen disease promotion have been understudied in food staple crops such as cassava. Cassava is a starchy root crop susceptible to cassava bacterial blight (CBB) a disease caused by the pathogen Xanthomonas phaseoli pv. manihotis (Xpm). Xpm and other bacterial pathogens use effector molecules to manipulate host genes that promote disease susceptibility. Xpm has specialized effector …

Fatal Crashes Rose In Alabama Over Past 3 Years, New Uab Study Finds, Matt Windsor

Browse All News

No abstract provided.

How To Protect Yourself From Travel Scams, Tehreem Khan

Browse All News

No abstract provided.

Regulation Of Nucleotide Excision Repair, Wenzhi Gong

LSU Doctoral Dissertations

Nucleotide excision repair (NER), a “cut and patch” mechanism, has two subpathways, namely transcription coupled repair (TCR) and global genome repair (GGR). TCR rapidly removes UV photoproduct (UV PP) in the transcribed strand (TS) of an actively transcribed gene, whereas GGR removes those DNA lesions throughout the genome. This dissertation mainly focused on identifying novel factors that function in NER and investigating the potential molecular mechanisms underlying initial damage recognition and downstream processes in NER. We identified Rpb7, a subunit of RNA polymerase II, represses TCR via its multiple regions. Specifically, the conserved region of Rpb7 that interacts with the …

Differences In Plant Hormone Responses Between Arabidopsis Thaliana And Schrenkiella Parvula Facing Lithium Toxicities, Jifeng Li

LSU Doctoral Dissertations

Investigating stress responses in plants is central to plant development studies and crop research. Identifying mechanisms of plant abiotic stress tolerance and adaptation will be keys to relieve the conflict between an increasing global population and declining agronomic land. Studies on extremophytes and their genetic responses to environmental stress are a way to help understand how and why these extremophile plants can develop well under extreme environments including high salinity and heavy metal toxicity. The studies herein first focus on comparative responses at the genetic level to lithium toxicity between Arabidopsis thaliana and Schrenkiella parvula. Based on elemental quantification …

Rad51 Foci As A Biomarker Predictive Of Platinum Chemotherapy Response In Ovarian Cancer, Amanda J Compadre, Lillian N Van Biljon, Mark C Valentine, Emily Graham, Bisiayo Fashemi, Emilee N Kotnik, Isaac Cooper, Lindsay M Kuroki, Carolyn K Mccourt, Andrea R Hagemann, Premal H Thaker, David G Mutch, Matthew A Powell, Lulu Sun, Nima Mosammaparast, Peinan Zhao, Elena Lomonosova, Dineo Khabele, Mary M Mullen, Et Al.

2020-Current year OA Pubs

PURPOSE: To determine the ability of RAD51 foci to predict platinum chemotherapy response in high-grade serous ovarian cancer (HGSOC) patient-derived samples.

EXPERIMENTAL DESIGN: RAD51 and γH2AX nuclear foci were evaluated by immunofluorescence in HGSOC patient-derived cell lines (n = 5), organoids (n = 11), and formalin-fixed, paraffin-embedded tumor samples (discovery n = 31, validation n = 148). Samples were defined as RAD51-High if >10% of geminin-positive cells had ≥5 RAD51 foci. Associations between RAD51 scores, platinum chemotherapy response, and survival were evaluated.

RESULTS: RAD51 scores correlated with in vitro response to platinum chemotherapy in established and primary ovarian cancer cell …

Comparison Of Patient Exit Interviews With Unannounced Standardised Patients For Assessing Hiv Service Delivery In Zambia: A Study Nested Within A Cluster Randomised Trial, Kombatende Sikombe, Aaloke Mody, Ingrid Eshun-Wilson, Elvin Geng, Et Al.

2020-Current year OA Pubs

OBJECTIVES: To compare unannounced standardised patient approach (eg, mystery clients) with typical exit interviews for assessing patient experiences in HIV care (eg, unfriendly providers, long waiting times). We hypothesise standardised patients would report more negative experiences than typical exit interviews affected by social desirability bias.

SETTING: Cross-sectional surveys in 16 government-operated HIV primary care clinics in Lusaka, Zambia providing antiretroviral therapy (ART).

PARTICIPANTS: 3526 participants aged ≥18 years receiving ART participated in the exit surveys between August 2019 and November 2021.

INTERVENTION: Systematic sample (every n

OUTCOME MEASURES: We compared patient experience among patients who received brief training prior to …

Early Antiretroviral Therapy Not Associated With Higher Cryptococcal Meningitis Mortality In People With Human Immunodeficiency Virus In High-Income Countries: An International Collaborative Cohort Study, Suzanne M Ingle, Elvin Geng, Et Al.

2020-Current year OA Pubs

BACKGROUND: Randomized controlled trials (RCTs) from low- and middle-income settings suggested that early initiation of antiretroviral therapy (ART) leads to higher mortality rates among people with HIV (PWH) who present with cryptococcal meningitis (CM). There is limited information about the impact of ART timing on mortality rates in similar people in high-income settings.

METHODS: Data on ART-naive PWH with CM diagnosed from 1994 to 2012 from Europe/North America were pooled from the COHERE, NA-ACCORD, and CNICS HIV cohort collaborations. Follow-up was considered to span from the date of CM diagnosis to earliest of the following: death, last follow-up, or 6 …

Phase Ii Trial Of Medi0457 And Durvalumab For Patients With Recurrent/Metastatic Human Papillomavirus-Associated Cancers, Van K Morris, Amir Jazaeri, Shannon N Westin, Curtis Pettaway, Solly George, Michaela Grinsfelder, Benny Johnson, David Vining, Ming Guo, Bryan Fellman, Michael Frumovitz

Faculty, Staff and Student Publications

BACKGROUND: Human papillomavirus (HPV) types 16/18 drive oncogenesis for most patients with cervical, anal, and penile cancers. MEDI0457, a therapeutic DNA vaccine containing plasmids for E6 and E7 HPV-16/18 viral oncogenes and IL-12 adjuvant, is safe and provokes an immune response against E6/E7. We tested MEDI0457 with the anti-PD-L1 antibody durvalumab for patients with HPV-associated cancers.

METHODS: Patients with recurrent/metastatic, treatment-refractory HPV-16/18 cervical cancer, or rare HPV-associated (anal and penile) cancers were eligible. Prior immune checkpoint inhibition was not permitted. Patients received MEDI0457 7 mg intramuscularly (weeks 1, 3, 7, 12, and every 8 weeks thereafter) and durvalumab 1500 mg …

A Phase Ib/Ii Study Of Ivosidenib With Venetoclax ± Azacitidine In Idh1-Mutated Myeloid Malignancies, Curtis A Lachowiez, Sanam Loghavi, Zhihong Zeng, Tomoyuki Tanaka, Yi June Kim, Sven Turkalj, Marlise R Luskin, Dzifa Y Duose, Rebecca S S Tidwell, Nicholas J Short, Gautam Borthakur, Tapan M Kadia, Lucia Masarova, George D Tippett, Prithviraj Bose, Elias J Jabbour, Farhad Ravandi, Naval G Daver, Guillermo Garcia-Manero, Hagop Kantarjian, Jacqueline S Garcia, Paresh Vyas, Koichi Takahashi, Marina Konopleva, Courtney D Dinardo

Faculty, Staff and Student Publications

UNLABELLED: The safety and efficacy of combining the isocitrate dehydrogenase-1 (IDH1) inhibitor ivosidenib (IVO) with the BCL2 inhibitor venetoclax (VEN; IVO + VEN) ± azacitidine (AZA; IVO + VEN + AZA) were evaluated in four cohorts of patients with IDH1-mutated myeloid malignancies (n = 31). Most (91%) adverse events were grade 1 or 2. The maximal tolerated dose was not reached. Composite complete remission with IVO + VEN + AZA versus IVO + VEN was 90% versus 83%. Among measurable residual disease (MRD)-evaluable patients (N = 16), 63% attained MRD--negative remissions; IDH1 mutation clearance occurred in 64% of patients receiving …