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Drug Reaction With Eosinophilia And Systemic Symptoms (Dress) Syndrome Caused By Apalutamide: A Case Presentation., Gabriella Martin, Evan Lambert, Gordon K. Wang

HPD Articles

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe drug reaction that is triggered several weeks after the start of a new medication. This syndrome presents with a variety of clinical symptoms, specifically a manifestation involving a fever followed by a severe rash. A variety of medications are known to trigger DRESS, with the most common being anticonvulsants and allopurinol. Here, we discuss the case of a medication, apalutamide, that caused DRESS in our patient. Early recognition and abrupt discontinuation of the medication is required for the management of this syndrome and to minimize morbidity and mortality.

Racial And Ethnic Disparities In Obesity And Contributions Of Social Determinants Of Health Among Boys With Autism Spectrum Disorder, Sandy Magaña, Misha Eliasziw, April Bowling, Aviva Must

Health Sciences Faculty Publications

Children with autism spectrum disorders (ASD) are at greater obesity risk compared to typically developing peers. Although many potential risk factors for this relationship have been identified, the causal chain must be better understood, particularly modifiable social determinants of obesity risk in ASD, and especially for children with ASD from minoritized racial/ethnic groups. We aimed to: (1) examine racial/ethnic disparities in obesity status in boys with ASD; (2) assess associations between social determinants of health and obesity status; and (3) understand if social determinants of health factors mediate the relationship between race/ethnicity and obesity status for these youth. We used …

Elucidating Interprotein Energy Transfer Dynamics Within The Antenna Network From Purple Bacteria, Dihao Wang, Olivia C. Fiebig, Dvir Harris, Hila Toporik, Yi Ji, Chern Chuang, Muath Nairat, Ashley L. Tong, John I. Ogren, Stephanie M. Hart, Jianshu Cao, James N. Sturgis, Yuval Mazor, Gabriela S. Schlau-Cohen

Chemistry: Faculty Publications

In photosynthesis, absorbed light energy transfers through a network of antenna proteins with near-unity quantum efficiency to reach the reaction center, which initiates the downstream biochemical reactions. While the energy transfer dynamics within individual antenna proteins have been extensively studied over the past decades, the dynamics between the proteins are poorly understood due to the heterogeneous organization of the network. Previously reported timescales averaged over such heterogeneity, obscuring individual interprotein energy transfer steps. Here, we isolated and interrogated interprotein energy transfer by embedding two variants of the primary antenna protein from purple bacteria, light-harvesting complex 2 (LH2), together into a …

Gardner-Webb Mission Team Provides Medical Care For Refugees In Athens, Greece, Office Of University Communications, Ashley Rich

Gardner-Webb NewsCenter Archive

A team consisting of two Gardner-Webb University faculty members and seven students traveled to Athens, Greece, to provide medical care for refugees from the surrounding area. For eight days in May 2023, the GWU mission team collaborated with local missionaries to help and encourage the people in need of care. Each member of the team shared that they walked away from the trip having learned something about their faith, themselves, and the impact that their service can have on the lives of others.

2023 Faculty And Staff Award Winners, Lindenwood University

Archived Lindenwood Press Releases

No abstract provided.

July 11, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Residential Metals Abatement Program (Rmap) Field Sampling Plan (Fsp) – Indoor Dust – Group 8 (Covering Goldhill Lutheran Church [Creativity Factory Preschool] And United Congregational [Crayon Academy Preschool]) (Dated June 30, 2023), Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Machine Learning Approach For Static Ransomware Analysis, Aldin Vehabovic

USF Tampa Graduate Theses and Dissertations

Ransomware is a form of malware which uses encryption methods to make data inaccessible to legitimate users. This cyberthreat has emerged as one of the most serious security challenges today, and a wide range of ransomware families have been developed and deployed, causing immense damage to governments, corporations, and private users. As this malware type continues to expand, governments across the world are taking serious steps to limit its reach. In addition, researchers have proposed a range of ransomware detection and attribution schemes, most of which use advanced machine learning (ML) techniques to process and analyze real-world empirical data from …

2023-07-11 Minutes, Morehead State University. Staff Congress.

Staff Congress Records

Staff Congress meeting minutes from July 11, 2023.

Cerebral Vasomotor Reactivity To Assess Brain Dysregulation In Post Covid Neurological Syndrome, Musharaf Mohiuddin

Health and Kinesiology Theses

Background: COVID-19 has wide-ranging physiological effects, with many patients complaining of persistent asthenia following recovery from the acute phase of the infection. The frequent term for this is Long Haul COVID (LHC). While we have tools to measure effects on general physiology in human subjects, a metric for cerebral dysregulation is lacking. Cerebral blood flow (CBF) is closely regulated in the healthy young person. Dysregulation has been well described in many conditions, including Posterior Reversible Encephalopathy Syndrome (PRES), and is associated with neurological deficits. Cerebral Vasomotor Reactivity was used as a tool to assess this dysregulation.

Methods: Transcranial Doppler (TCD) …

High Glucose-Upregulated Pd-L1 Expression Through Ras Signaling-Driven Downregulation Of Ptrh1 Leads To Suppression Of T Cell Cytotoxic Function In Tumor Environment, Chenggang Gao, Jiaoshun Chen, Jianwei Bai, Haoxiang Zhang, Yanyi Tao, Shihong Wu, Hehe Li, Heshui Wu, Qiang Shen, Tao Yin

School of Graduate Studies Faculty Publications

Background: Nearly 80% of patients with pancreatic cancer suffer from glucose intolerance or diabetes. Pancreatic cancer complicated by diabetes has a more immunosuppressive tumor microenvironment (TME) and is associated with a worse prognosis. The relationship between glucose metabolism and programmed cell death-Ligand 1 (PD-L1) is close and complex. It is important to explore the regulation of high glucose on PD-L1 expression in pancreatic cancer and its effect on infiltrating immune effectors in the tumor microenvironment. Methods: Diabetic murine models (C57BL/6) were used to reveal different immune landscape in euglycemic and hyperglycemic pancreatic tumor microenvironment. Bioinformatics, WB, iRIP [Improved RNA Binding …

Older Adults With A History Of Psychiatric Conditions Experience More Cognitive Decline Than Older Adults Without This History, Maria T. Brown, Miriam Mutambudzi

Population Health Research Brief Series

Having psychiatric conditions (such as bipolar disorder, schizophrenia, and major depressive disorder) throughout one’s life can lead to faster rates of cognitive decline as one ages. This data slice explores the associations between psychiatric history and cognitive function among U.S. White, Black, and Hispanic adults ages 65 and older from 1995-2014. Findings demonstrate that having a history of psychiatric problems is related to lower cognitive functioning and a faster rate of cognitive decline for all three groups, but Black and Hispanic adults experience steeper declines compared with White adults.

Repeating Success, Setting Record, Edwin Smith

University of Mississippi News

University makes Phi Theta Kappa Transfer Student Honor Roll for eighth consecutive year

The Characteristics Of Successful Military It Projects: A Cross-Country Empirical Study, Helene Berg, Jonathan D. Ritschel

Faculty Publications

In the armed forces, successful digitalization is crucial to ensure effective operations. Much of the existing literature on project factors during the planning and execution phases of public IT projects do not focus specifically on military sector projects. Therefore, the paper aims to provide empirical insights into the characteristics of successful military IT projects. Data from such projects in NATO countries and agencies were collected through interviews and project documents. The findings relating to the main variable of interest, “delivery of client benefit,” supported previous findings on IT project performance. Medium-sized projects performed better than small and large projects, and …

Credit Suisse Crash Investigated By Swiss Lawmakers, John Revill, Tomasz Janowski

Documents

No abstract provided.

Rn To Bsn End-Of-Program Evaluation Revision, Nichol Tate

Doctor of Nursing Practice Projects

The data in an end-of-a-program student survey are crucial for maintaining a high-quality program and meeting accreditation standards. This quality improvement project aims to formulate a revised end-of-program evaluation survey for graduates to use to provide feedback to make necessary improvements to the program and employ better communication and access to educators for students to feel connected and important. After the item analysis method was used to review the questions and revise the survey, the revision of the survey was sent to the current summer RN to BSN students to complete and provide data about the overall program. Another method …

The Manufacturing Sector Pushes Upward, Anderson Center For Economic Research

Anderson Center Press Releases

No abstract provided.

Editor’S Introduction, Michael D.; Pante

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Phenylpropionic Acid Produced By Gut Microbiota Alleviates Acetaminophen-Induced Hepatotoxicity, Sungjoon Cho, Xiaotong Yang, Kyoung-Jae Won, Vanessa A. Leone, Eugene B. Chang, Grace Guzman, Hyunwoo Lee, Hyungyoung Jeong

Purdue University Libraries Open Access Publishing Fund

The gut microbiota affects hepatic drug metabolism. However, gut microbial factors modulating hepatic drug metabolism are largely unknown. In this study, using a mouse model of acetaminophen (APAP)-induced hepatotoxicity, we identified a gut bacterial metabolite that controls the hepatic expression of CYP2E1 that catalyzes the conversion of APAP to a reactive, toxic metabolite. By comparing C57BL/6 substrain mice from two different vendors, Jackson (6J) and Taconic (6N), which are genetically similar but harbor different gut microbiotas, we established that the differences in the gut microbiotas result in differential susceptibility to APAP-induced hepatotoxicity. 6J mice exhibited lower susceptibility to APAP-induced hepatotoxicity …

432-434 Realty Llc V. Falkenheimer

All Decisions

ERAP Case. Handwritten Opinion.

Hlp1 Mru Llc V. Ishrak

All Decisions

No abstract provided.

Housing Fever In Australia 2020-2023: Insights From An Econometric Thermometer, Shuping Shi, Peter C. B. Phillips

Cowles Foundation Discussion Papers

Australian housing markets experienced widespread and, in some cases, extraordi-nary growth in prices between 2020 and 2023. Using recently developed methodology that accounts for fundamental economic drivers, we assess the existence and degree of speculative behaviour as well as the timing of exuberance and downturns in these markets. Our findings indicate that speculative behaviour was indeed present in six of the eight capital cities at some time over the period studied. The sequence of events in this nation-wide housing bubble began in the Brisbane market and concluded in Melbourne, Canberra, and Hobart following the interest rate hike implemented by the …

Policy Evaluation With Nonlinear Trended Outcomes: Covid-19 Vaccination Rates In The Us, Lynn Bergeland Morgan, Peter C. B. Phillips, Donggyu Sul

Cowles Foundation Discussion Papers

This paper points out some pitfalls in the use of two-way fixed effects (TWFE) regressions when outcome variables contain nonlinear or stochastic trend components. When a policy change shifts trend paths of outcome variables conventional TWFE estimation can distort results and invalidate inference. A robust solution is proposed by identifying determinants of dynamic club membership based on the idea of relative convergence, which can be assessed empirically by the so-called ‘logt’ test (Phillips & Sul, 2007a). Club membership in each time period is estimated by recursive regression, transforming outcome variables to statistically stable, stationary status. Time varying club membership can …

Linked Data Via Vivaldi: A Musical Journey From Wikidata To The Library Catalog, Emma Clarkson, Steven Folsom, Huda Khan, Kevin Kishimoto, Astrid Usong, Rachel Evans

Presentations

In collaboration with the Music Library Association Linked Data Working Group (MLA LDWG), and as part of the Linked Data for Production: Closing the Loop (LD4P3) grant, Cornell University and Stanford University explored the integration of Wikidata properties describing musical works into a Cornell library catalog prototype. In this presentation, we will briefly describe the MLA LDWG’s project to add thematic catalog codes and other information to musical works represented in Wikidata. We will review the design, development, and usability testing of a Cornell library catalog prototype that integrated these Wikidata properties.

We will also discuss the specific choices we …

Tissue Resident Regulatory T Cells And Immunopathology During Influenza Infections, Michael Mcgee

LSU Doctoral Dissertations

Influenza (flu) virus infections are a leading cause of respiratory illness. Globally there are approximately 290,000-650,000 deaths and 3-5 million cases of severe illness during the average flu season. Severe flu infection is associated with the combination of a strong pro-inflammatory and weak anti-inflammatory response. Regulatory T cell subsets suppress pro-inflammatory responses during flu infection, with production of the immunomodulatory cytokine IL-10 playing a critical role in this process. Tissue resident regulatory T cell subsets are maintained within nonlymphoid tissues and are optimally positioned to suppress localized pro-inflammatory responses. However, knowledge of the signaling pathways regulating the development of tissue …

The Impact Of Covid-19 On The Financial Performance Of Largest Teaching Hospitals, Tiffany Champagne-Langabeer, James R Langabeer

Faculty, Staff and Student Publications

The COVID-19 pandemic disrupted hospital operations. Anecdotal evidence suggests financial performance likewise suffered, yet little empirical research supports this claim. This study aimed to explore the impact of the pandemic on the financial performance of the most prominent academic hospitals in the United States. Data from the 115 largest major teaching hospitals in the United States were extracted from the American Hospital Directory for three years (2019-2021). We hypothesized that the year and region would moderate the relationship between a hospital's return on assets (financial performance) and specific operational variables. We found evidence through descriptive statistics and multivariate moderated regressions …

Between The Stacks, 07-2023, Anna Swearengen, Michelle Dry, Marie Peeples, Accessibility Committee

Between the Stacks

The July 2023 edition of the University Libraries monthly newsletter presenting a calendar of events for the month, library announcements, photos and information from many summer library conferences including the American Library Association (ALA) conference, and an article from the Accessibility Committee on PDFs.

The Rise And Evolution Of Wind Tower Designs In Egypt And The Middle East, Marian A. Nessim, Aya Elshabshiri, Virginia Bassily, Niriman Soliman

Faculty Journal Articles

No abstract provided.

Controls On The Stratiform Copper Mineralization In The Western Syncline, Upper Peninsula, Michigan, William C. Williams, Theodore J. Bornhorst

Michigan Tech Publications

The Western Syncline hosts reduced-facies, or Kupferschiefer-type, sedimentary rock-hosted stratiform Cu deposits (SSC) in the lowermost meters of the Nonesuch Formation, which is part of a thick section of clastic sedimentary rocks that comprise the upper fill of the Mesoproterozoic Midcontinent Rift of North America. Located in the Porcupine Mountains Cu district in Upper Peninsula, Michigan, these blind deposits were discovered in 1956, but are not yet developed, although recent renewed interest may result in near-term production. The deposits are distinguished by their relatively undeformed nature and lack of superposed hydrothermal events. Prior to lithification, chalcocite mineralization replaced diagenetic pyrite …

All That Is Cyber Melts Into Control: A Rhetorical Analysis Of Cybernetic Metaphors, Cem İsmail Addemir

Theses and Dissertations

This thesis historicizes and interprets the logic of cybernetics as a communication technology and how it shaped notions of control in the mid-20th century. To situate my analysis, I focus on cybernetics, the tradition within communication studies that focuses on controlling communication through the application of feedback loops to a particular system. Since the discovery and popularization of cybernetics by the late 1950s, its central logic has been widely applied to computational technology and influenced future systems theories. Specifically, my thesis employs a rhetorical examination of cybernetic metaphors through metaphor criticism to trace the genealogy of cybernetic discourses that I …