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Coastal Environments: Mine Discharges And Infringements On Indigenous Peoples’ Rights, Charles Kerfoot, Gary Swain, Luis M. Verissimo, Erin Johnston, Carol Maclennan, Daniel Schneider, Noel Urban Jul 2023

Coastal Environments: Mine Discharges And Infringements On Indigenous Peoples’ Rights, Charles Kerfoot, Gary Swain, Luis M. Verissimo, Erin Johnston, Carol Maclennan, Daniel Schneider, Noel Urban

Michigan Tech Publications

Over a century ago, copper mills on the Keweenaw Peninsula of Lake Superior sluiced 64 million metric tonnes (MMT) of tailings into coastal waters, creating a metal-rich “halo”. Here we show that relatively small discharges can spread widely in time and space. Mass Mill (2.9 MMT) dumping into Lake Superior also illustrates the complexity of interactions with Indigenous Peoples. A combination of aerial photos, LiDAR, and a microscope technique for distinguishing end-member particles traces the migration of tailings. The clay fraction spread rapidly across Keweenaw Bay and curled into terminal L’Anse Bay, within tribal Reservation boundaries. The coarse stamp sand …


A Spatially Anchored Transcriptomic Atlas Of The Human Kidney Papilla Identifies Significant Immune Injury In Patients With Stone Disease, Victor Hugo Canela, Joseph P Gaut, Sanjay Jain, Et Al. Jul 2023

A Spatially Anchored Transcriptomic Atlas Of The Human Kidney Papilla Identifies Significant Immune Injury In Patients With Stone Disease, Victor Hugo Canela, Joseph P Gaut, Sanjay Jain, Et Al.

2020-Current year OA Pubs

Kidney stone disease causes significant morbidity and increases health care utilization. In this work, we decipher the cellular and molecular niche of the human renal papilla in patients with calcium oxalate (CaOx) stone disease and healthy subjects. In addition to identifying cell types important in papillary physiology, we characterize collecting duct cell subtypes and an undifferentiated epithelial cell type that was more prevalent in stone patients. Despite the focal nature of mineral deposition in nephrolithiasis, we uncover a global injury signature characterized by immune activation, oxidative stress and extracellular matrix remodeling. We also identify the association of MMP7 and MMP9 …


Segmentation Of Human Functional Tissue Units In Support Of A Human Reference Atlas, Yashvardhan Jain, Leah L Godwin, Yingnan Ju, Naveksha Sood, Ellen M Quardokus, Andreas Bueckle, Teri Longacre, Aaron Horning, Yiing Lin, Edward D Esplin, John W Hickey, Michael P Snyder, Nathan Heath Patterson, Jeffrey M Spraggins, Katy Börner Jul 2023

Segmentation Of Human Functional Tissue Units In Support Of A Human Reference Atlas, Yashvardhan Jain, Leah L Godwin, Yingnan Ju, Naveksha Sood, Ellen M Quardokus, Andreas Bueckle, Teri Longacre, Aaron Horning, Yiing Lin, Edward D Esplin, John W Hickey, Michael P Snyder, Nathan Heath Patterson, Jeffrey M Spraggins, Katy Börner

2020-Current year OA Pubs

The Human BioMolecular Atlas Program (HuBMAP) aims to compile a Human Reference Atlas (HRA) for the healthy adult body at the cellular level. Functional tissue units (FTUs), relevant for HRA construction, are of pathobiological significance. Manual segmentation of FTUs does not scale; highly accurate and performant, open-source machine-learning algorithms are needed. We designed and hosted a Kaggle competition that focused on development of such algorithms and 1200 teams from 60 countries participated. We present the competition outcomes and an expanded analysis of the winning algorithms on additional kidney and colon tissue data, and conduct a pilot study to understand spatial …


Bound Preserving Numerical Methods For Infiltration, Arnob Barua Jul 2023

Bound Preserving Numerical Methods For Infiltration, Arnob Barua

LSU Master's Theses

Simulating the infiltration process in variably saturated media by solving Richards' Equation (RE) remains a computationally challenging task. The degenerate parabolic nature of RE, along with the strongly nonlinear coefficients, makes it very difficult to obtain accurate solutions with conventional numerical methods unless highly refined meshes are used. That is, in the conventional Finite Element Method (FEM), the grid size has to be fine enough to ensure convergence and limit non-physical oscillations, which is computationally expensive. This research aims to develop a second-order accurate FEM discretization with no non-physical oscillations for RE on unstructured meshes which will converge faster than …


Thinking Outside The Dyad: Incorporating Cohort-Based Experiences Into Mentorship, Angela Yon, Grace Allbaugh, Susan Franzen Jul 2023

Thinking Outside The Dyad: Incorporating Cohort-Based Experiences Into Mentorship, Angela Yon, Grace Allbaugh, Susan Franzen

Faculty and Staff Publications – Milner Library

A benefit of the traditional one-to-one, hierarchical mentoring relationship is the individualized attention and guidance the mentor provides the mentee. This singular mentoring relationship can be effective but is not always sufficient in addressing institutional acculturation and meeting personal needs of the new employee. This paper discusses how an emergent mentoring program at Milner Library blended the dyadic mentoring relationship with cohort-based programming to create a space for participants to learn from colleagues across departments, share experiences, and consider psychosocial issues. These grassroots programming efforts have cultivated holistic engagement and renewed community.


Local And Long-Distance Organization Of Prefrontal Cortex Circuits In The Marmoset Brain, Akiya Watakabe, David C Van Essen, Et Al. Jul 2023

Local And Long-Distance Organization Of Prefrontal Cortex Circuits In The Marmoset Brain, Akiya Watakabe, David C Van Essen, Et Al.

2020-Current year OA Pubs

The prefrontal cortex (PFC) has dramatically expanded in primates, but its organization and interactions with other brain regions are only partially understood. We performed high-resolution connectomic mapping of the marmoset PFC and found two contrasting corticocortical and corticostriatal projection patterns: "patchy" projections that formed many columns of submillimeter scale in nearby and distant regions and "diffuse" projections that spread widely across the cortex and striatum. Parcellation-free analyses revealed representations of PFC gradients in these projections' local and global distribution patterns. We also demonstrated column-scale precision of reciprocal corticocortical connectivity, suggesting that PFC contains a mosaic of discrete columns. Diffuse projections …


Loss Of Function Mutation In Ank Causes Aberrant Mineralization And Acquisition Of Osteoblast-Like-Phenotype By The Cells Of The Intervertebral Disc, Takashi Ohnishi, Victoria Tran, Kimheak Sao, Pranay Ramteke, William Querido, Ruteja A Barve, Koen Van De Wetering, Makarand V Risbud Jul 2023

Loss Of Function Mutation In Ank Causes Aberrant Mineralization And Acquisition Of Osteoblast-Like-Phenotype By The Cells Of The Intervertebral Disc, Takashi Ohnishi, Victoria Tran, Kimheak Sao, Pranay Ramteke, William Querido, Ruteja A Barve, Koen Van De Wetering, Makarand V Risbud

2020-Current year OA Pubs

Pathological mineralization of intervertebral disc is debilitating and painful and linked to disc degeneration in a subset of human patients. An adenosine triphosphate efflux transporter, progressive ankylosis (ANK) is a regulator of extracellular inorganic pyrophosphate levels and plays an important role in tissue mineralization. However, the function of ANK in intervertebral disc has not been fully explored. Herein we analyzed the spinal phenotype of Ank mutant mice (ank/ank) with attenuated ANK function. Micro-computed tomography and histological analysis showed that loss of ANK function results in the aberrant annulus fibrosus mineralization and peripheral disc fusions with cranial to caudal progression in …


Βii-Spectrin Is Required For Synaptic Positioning During Retinal Development, Joseph T Anderson, Akash Maheshwari, Elizabeth Zuniga-Sanchez Jul 2023

Βii-Spectrin Is Required For Synaptic Positioning During Retinal Development, Joseph T Anderson, Akash Maheshwari, Elizabeth Zuniga-Sanchez

Faculty, Staff and Students Publications

Neural circuit assembly is a multistep process where synaptic partners are often born at distinct developmental stages, and yet they must find each other and form precise synaptic connections with one another. This developmental process often relies on late-born neurons extending their processes to the appropriate layer to find and make synaptic connections to their early-born targets. The molecular mechanism responsible for the integration of late-born neurons into an emerging neural circuit remains unclear. Here, we uncovered a new role for the cytoskeletal protein βII-spectrin in properly positioning presynaptic and postsynaptic neurons to the developing synaptic layer. Loss of βII-spectrin …


Resonant Inner-Shell Photofragmentation Of Adamantane (C10h16), Smita Ganguly, Mathieu Gisselbrecht, Per Eng-Johnsson, Raimund Feifel, Sergio Díaz-Tendero, Eva Muchová, Aleksandar R Milosavljević, Patrick Rousseau, Sylvain Maclot Jul 2023

Resonant Inner-Shell Photofragmentation Of Adamantane (C10h16), Smita Ganguly, Mathieu Gisselbrecht, Per Eng-Johnsson, Raimund Feifel, Sergio Díaz-Tendero, Eva Muchová, Aleksandar R Milosavljević, Patrick Rousseau, Sylvain Maclot

Faculty, Staff and Students Publications

Adamantane, the smallest diamondoid molecule with a symmetrical cage, contains two distinct carbon sites, CH and CH2. The ionization/excitation of the molecule leads to the cage opening and strong structural reorganization. While theoretical predictions suggest that the carbon site CH primarily causes the cage opening, the role of the other CH2 site remains unclear. In this study, we used advanced experimental Auger electron-ion coincidence techniques and theoretical calculations to investigate the fragmentation dynamics of adamantane after resonant inner-shell photoexcitation. Our results demonstrate that some fragmentation channels exhibit site-sensitivity of the initial core-hole location, indicating that different carbon site excitations could …


General Motors Overseas Corporation V Acit – (Itat Mumbai), Pragya Kaushik Jul 2023

General Motors Overseas Corporation V Acit – (Itat Mumbai), Pragya Kaushik

National Law School Business Law Review

No abstract provided.


List Of Funeral Services And Costs Jul 2023

List Of Funeral Services And Costs

Holmes Funeral Home Bills and Correspondence, 1923-1943

Note: Handwritten list of of funeral services and cost. No date given.


William H Suttles, Barber, William H. Suttles Jul 2023

William H Suttles, Barber, William H. Suttles

Holmes Funeral Home Bills and Correspondence, 1923-1943

Business card: Wm.H. Suttles, Barber, First Class Services249 E. 35th St. Res. 3120 Cottage Grove Ave. Chicago, Illinois. Phones: Shop Douglas 4599, Residence Douglas 6972. No date given


Mrs. Bessie M. Taylor-Shaw Jul 2023

Mrs. Bessie M. Taylor-Shaw

Holmes Funeral Home Bills and Correspondence, 1923-1943

Calling card: Mrs. Bessie M. Taylor-Shaw 410 Broad Street Jacksonville Florida. No date given


Pangle's The Exclusive Floor Covering Store, Pangle's Jul 2023

Pangle's The Exclusive Floor Covering Store, Pangle's

Holmes Funeral Home Bills and Correspondence, 1923-1943

Business card: R.W. Cantrell, Pangles 338 West Forsyth St. Jacksonville, Florida. Phone 5-4583. W.D. Pangle, Owner. Handwritten note on back: about 33.50 per mo. No date given.


Mrs. Arvilla Ross - Mrs. R. Holmes Walker, No Date Given, Arvilla Ross Jul 2023

Mrs. Arvilla Ross - Mrs. R. Holmes Walker, No Date Given, Arvilla Ross

Holmes Funeral Home Bills and Correspondence, 1923-1943

Correspondence: Letter from Mrs. Ross, Gainesville, Florida, to Mrs. Rosa G. Holmes Walker, requesting acknowledgment and a receipt for payments made for Phena [Nelmon's] funeral expenses


Advertisement, Maxwell Copper-Alloy Burial Products, Maxwell Burial Products Jul 2023

Advertisement, Maxwell Copper-Alloy Burial Products, Maxwell Burial Products

Holmes Funeral Home Bills and Correspondence, 1923-1943

Pamphlet: Maxwell copper alloy burial products distributed by Florida Casket Company, Jacksonville, Florida. No date given


Advertisement, Huntley's Grape Juice, Chapman Sales Company, Chapman Sales Company Jul 2023

Advertisement, Huntley's Grape Juice, Chapman Sales Company, Chapman Sales Company

Holmes Funeral Home Bills and Correspondence, 1923-1943

Correspondence: Letter from Chapman Sales Company, distributors and brokers of Chautauqua Maid and Huntley's Grape Juice, 921, Lynch Building, Jacksonville, Florida - advertisement letter for Huntley's Grape Juice. No date given.


Advertisement, G. P. Putnam's Sons, G. P. Putnam's Sons Jul 2023

Advertisement, G. P. Putnam's Sons, G. P. Putnam's Sons

Holmes Funeral Home Bills and Correspondence, 1923-1943

Pamphlet: G.P. Putnam's Sons Publishers and Booksellers advertisement for Putnam;s Minute-A-Day English For Busy People. No date given.


Notes, No Date Given. Jul 2023

Notes, No Date Given.

Holmes Funeral Home Bills and Correspondence, 1923-1943

Notes: Handwritten notes stating Mr. Gadson wants body brought to house Friday night where pallbearers promised 3 cars Saturday morning; Mrs. Reynolds on Jessie St. wants to see you.


An Unknown Sacrifice, Earl Clement Davis Jul 2023

An Unknown Sacrifice, Earl Clement Davis

Education

A seemingly unfinished bit of story about a son leaving home.

This is from a collection of manuscripts—mostly class papers— written while Davis was a student at Harvard Divinity School, 1902-1904. This manuscript is undated and not obviously connected to any specific class.

The primary downloadable document contains the original document followed by the transcription. The bottom of each item page also features the primary document as an embedded pdf for browsing.

Transcription by Davis Baird. Item description based off writing and context provided by Davis Baird.


Regional Aquatic Macroinvertebrate Biodiversity, Sally Sir, Kris N. White Ph.D. Jul 2023

Regional Aquatic Macroinvertebrate Biodiversity, Sally Sir, Kris N. White Ph.D.

Georgia Journal of Science

Macroinvertebrates are sensitive to environmental conditions, giving them the ability to be utilized in studies indicating the health of their environment. Additionally, macroinvertebrates are an important food source for vertebrates and invertebrates. Since macroinvertebrates play such significant roles in the ecosystem, it is important to identify and document their presence. In order to begin documenting the macroinvertebrates in central Georgia, aquatic macroinvertebrates were collected from ten sampling sites along a transect of central Georgia. Live specimens were imaged, preserved, identified, and sequenced. COI mitochondrial DNA and 18s nuclear DNA and 3D images of the organisms were made publicly available. The …


Application Of Machine Learning Algorithm For Creating Sustainable Omni-Channel Retail Ecosystem, Somedip Karmakar, Anuja Shukla Jul 2023

Application Of Machine Learning Algorithm For Creating Sustainable Omni-Channel Retail Ecosystem, Somedip Karmakar, Anuja Shukla

Management Dynamics

The retail ecosystem has evolved from simple Kirana stores to large omni-channel retail systems. The advent of omni-channel retailing has seen an increased count of fraudsters who can abuse the gap between the online and offline channels to perform different types of fraudulent activities. Fraud can be related to payment, account take over, refund and cancellation abuse, collusion of customers with associates. Waste can be due to over-production, sub-optimal pricing or discounts, damaged products, throwaways, availability issues, packaging waste. The paper tries to identify the need for better research on improvement in fraud detection systems for sparse data, improvement of …


Sustainability Of Permanent Grassland On A Low Moor Soil With Different N And K Nutrient Management, K. Orlovius, J. Pickert Jul 2023

Sustainability Of Permanent Grassland On A Low Moor Soil With Different N And K Nutrient Management, K. Orlovius, J. Pickert

IGC Proceedings (1977-2023)

After the reunification of Germany fertilisation with P and K was strongly reduced in the eastern states of Germany due to the poor financial situation of the farms. Particularly on sites with a low nutrient delivery capacity, such a nutrient management strategy implies the risk of decreasing soil fertility. On a low moor soil with permanent grassland a 4 - year trial with different N and K fertilisation was set up to study the development of dry matter production and K concentrations in the grass.


Genese Mercer Jul 2023

Genese Mercer

African American Funeral Programs

Announcement of death from James R. Barnes Mortuary.


Jeffrey N. Johnson, Jeffrey Johnson Jul 2023

Jeffrey N. Johnson, Jeffrey Johnson

Virginia Poets Database: A Literary and Educational Resource

No abstract provided.


Discerning Lines To The Regulation Of Chartered Accountants In India, Aman Chaudhary, Hiral Chheda Jul 2023

Discerning Lines To The Regulation Of Chartered Accountants In India, Aman Chaudhary, Hiral Chheda

National Law School Business Law Review

No abstract provided.


Case Note: Judgment Of The Supreme Court In The Essar Steel Case, Rajat Sethi, Aditi Agarwal Jul 2023

Case Note: Judgment Of The Supreme Court In The Essar Steel Case, Rajat Sethi, Aditi Agarwal

National Law School Business Law Review

No abstract provided.


The Meld Model: The Holy Grail Of Indian Corporate Jurisprudence, Rahul Singh Jul 2023

The Meld Model: The Holy Grail Of Indian Corporate Jurisprudence, Rahul Singh

National Law School Business Law Review

No abstract provided.


Procedural Fairness In Securities Enforcement, Shruti Rajan Jul 2023

Procedural Fairness In Securities Enforcement, Shruti Rajan

National Law School Business Law Review

No abstract provided.


Termination Of Contracts During The Moratorium: Looking Beyond The ‘Going Concern’ Status, Amrit Mahal Jul 2023

Termination Of Contracts During The Moratorium: Looking Beyond The ‘Going Concern’ Status, Amrit Mahal

National Law School Business Law Review

No abstract provided.