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Articles 529081 - 529110 of 5209320
Full-Text Articles in Entire DC Network
College Of Business News, Georgia Southern University
College Of Business News, Georgia Southern University
College of Business: News & Publications
- Schiman Evaluates Charter Schools
Supplemental Files: Laser Scanner-Based Robotic Coordinate Measuring Machine, Vladimir Gurau
Supplemental Files: Laser Scanner-Based Robotic Coordinate Measuring Machine, Vladimir Gurau
Datasets
This data represents the LabView and C++ software necessary to operate the coordinate measuring machine (CMM) described in the related publication, as well as raw data results representing the digitized model of a section of a turbine blade obtained using the CMM. This data is shared as supplemental material for the related publication: V. Gurau, A. Gerhardstein, K. Carruthers and H. Frazer: “Laser Scanner-Based Robotic Coordinate Measuring Machine”, in International Journal of Mechanical Engineering and Robotics Research (2023).
Rapid Implementation Of Veterans Health Administration Telehealth Creative Arts Therapies: Survey Evaluation Of Adoption And Adaptation, Kristin M. Story, Mindy Flanagan, Sheri L. Robb, Dawn M. Bravata, Matthew J. Bair, David Otto, Teresa M. Damush
Rapid Implementation Of Veterans Health Administration Telehealth Creative Arts Therapies: Survey Evaluation Of Adoption And Adaptation, Kristin M. Story, Mindy Flanagan, Sheri L. Robb, Dawn M. Bravata, Matthew J. Bair, David Otto, Teresa M. Damush
Health Services and Informatics Research
Background
Creative arts therapies (CAT) are employed throughout the Veterans Health Administration (VHA) and are predominantly delivered in-person. Though telehealth delivery of CAT was used at several VHA facilities to increase services to rural Veterans, due to guidance from the Center for Disease Control and VHA that temporarily suspended or reduced in-person services, there was a large increase of CAT therapists enterprise-wide who adopted telehealth delivery. The aims of this study were to evaluate adoption and adaptation of CAT telehealth delivery and identify related barriers and facilitators.
Methods
We deployed a survey guided by the Consolidated Framework for Implementation Research …
A Risk Assessment For The Remote Ocean: The Case Of The South East Atlantic, Holly J. Niner, Siân E. Rees, Giulia La Bianca, Kirsty A. Mcquaid, Kerry L. Howell
A Risk Assessment For The Remote Ocean: The Case Of The South East Atlantic, Holly J. Niner, Siân E. Rees, Giulia La Bianca, Kirsty A. Mcquaid, Kerry L. Howell
School of Biological and Marine Sciences
Degradation of the natural world and associated ecosystem services is attributed to a historical failure to include its ‘value’ in decision-making. Uncertainty in the quantification of the relationship between natural capital ‘assets’ that give rise to critical societal benefits and people is one reason for the omission of these values from natural resource management. As this uncertainty increases in marine systems and further still with distance from the coast, the connection between society and natural capital assets is less likely to be included adequately in decision-making. Natural capital assets of Areas Beyond National Jurisdiction (ABNJ), including those of the deep …
New Hampshire Democratic Primary Voters Unenthusiastic But Back Biden 7/19/2023, Unh Survey Center
New Hampshire Democratic Primary Voters Unenthusiastic But Back Biden 7/19/2023, Unh Survey Center
All UNH Survey Center Polls
Seven in ten likely 2024 New Hampshire Democratic presidential primary voters currently back President Joe Biden. Half of Biden supporters are not enthusiastic if Biden is the 2024 Democratic nominee, but most supporters plan to vote for Biden even if he does not appear on the ballot. There is little interest in challengers Robert F. Kennedy Jr. or Marianne Williamson, both of whom are unpopular among likely Democratic primary voters and few Biden supporters even consider either Kennedy or Williamson to be their second choice.
Interpretable Timbre Synthesis Using Variational Autoencoders Regularized On Timbre Descriptors, Anastasia Natsiou, Luca Longo, Sean O'Leary
Interpretable Timbre Synthesis Using Variational Autoencoders Regularized On Timbre Descriptors, Anastasia Natsiou, Luca Longo, Sean O'Leary
Conference papers
Controllable timbre synthesis has been a subject of research for several decades, and deep neural networks have been the most successful in this area. Deep generative models such as Variational Autoencoders (VAEs) have the ability to generate a high-level representation of audio while providing a structured latent space. Despite their advantages, the interpretability of these latent spaces in terms of human perception is often limited. To address this limitation and enhance the control over timbre generation, we propose a regularized VAE-based latent space that incorporates timbre descriptors. Moreover, we suggest a more concise representation of sound by utilizing its harmonic …
Re: Comment Letter For The Butte Priority Soils Operable Unit (Bpsou) Draft Final Quarterly Operations And Maintenance Report Butte Treatment Lagoon System – Fourth Quarter 2022 (Dated March 30, 2023), Nikia Greene
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Office Of Research, Economic Engagement And Outreach Update, July 19, 2023, Office Of Research, Economic Engagement And Outreach
Office Of Research, Economic Engagement And Outreach Update, July 19, 2023, Office Of Research, Economic Engagement And Outreach
Office of Research, Economic Engagement and Outreach
No abstract provided.
Associations Between Neuropsychiatric Symptoms And Adrd Serum Biomarkers In Mexican American And Non-Hispanic White Adults With Mild Cognitive Impairment, Valentina R. Garbarino, Tiffany F. Kautz, Hector Trevino, Gabriel A. Vela, Vinu Philip, Ashley Laroche, Amy R. Saklad, Eric L. Shipp, Claudia L. Satizabal, Gladys E. Maestre
Associations Between Neuropsychiatric Symptoms And Adrd Serum Biomarkers In Mexican American And Non-Hispanic White Adults With Mild Cognitive Impairment, Valentina R. Garbarino, Tiffany F. Kautz, Hector Trevino, Gabriel A. Vela, Vinu Philip, Ashley Laroche, Amy R. Saklad, Eric L. Shipp, Claudia L. Satizabal, Gladys E. Maestre
School of Medicine Publications
Background: Mild cognitive impairment (MCI) is a heterogenous diagnostic category with trajectories ranging from reversion to unimpaired cognition to progression to dementia. Neuropsychiatric symptoms such as depression and irritability are common and influence quality of life of patients and caregivers. The role of neuropsychiatric symptoms on disease biology, presentation, and course remains poorly understood. The goal of this study was to evaluate the associations between neuropsychiatric symptoms and serum ADRD biomarkers in Mexican American and non-Hispanic white participants diagnosed with MCI.
Method: Participants from the Texas Alzheimer’s Research and Care Consortium underwent a blood draw and clinical evaluation, including psychopathological …
Smokejumper Obituary: Deinema, John William "Jack" (Mccall 1950), National Smokejumper Association
Smokejumper Obituary: Deinema, John William "Jack" (Mccall 1950), National Smokejumper Association
Smokejumper Obituaries
No abstract provided.
Smokejumper Obituary: Lince, Jack L. (North Cascades 1950), National Smokejumper Association
Smokejumper Obituary: Lince, Jack L. (North Cascades 1950), National Smokejumper Association
Smokejumper Obituaries
No abstract provided.
Sars‑Cov‑2 Entry Into And Evolution Within A Skilled Nursing Facility, Nicole R. Sexton, Parker Parker Cline, Emily N. Gallichotte, Emily Fitzmeyer, Michael C. Young, Ashley J. Janich, Kristy L. Pabilonia, Nicole Ehrhart, Gregory D. Ebel
Sars‑Cov‑2 Entry Into And Evolution Within A Skilled Nursing Facility, Nicole R. Sexton, Parker Parker Cline, Emily N. Gallichotte, Emily Fitzmeyer, Michael C. Young, Ashley J. Janich, Kristy L. Pabilonia, Nicole Ehrhart, Gregory D. Ebel
Nebraska Center for Virology: Faculty Publications
SARS-CoV-2 belongs to the family Coronaviridae which includes multiple human pathogens that have an outsized impact on aging populations. As a novel human pathogen, SARS-CoV-2 is undergoing continuous adaptation to this new host species and there is evidence of this throughout the scientific and public literature. However, most investigations of SARS-CoV-2 evolution have focused on largescale collections of data across diverse populations and/or living environments. Here we investigate SARS-CoV-2 evolution in epidemiologically linked individuals within a single outbreak at a skilled nursing facility beginning with initial introduction of the pathogen. The data demonstrate that SARSCoV- 2 was introduced to the …
Computation Of The Basic Reproduction Numbers For Reaction-Diffusion Epidemic Models, Chayu Yang, Jin Wang
Computation Of The Basic Reproduction Numbers For Reaction-Diffusion Epidemic Models, Chayu Yang, Jin Wang
Department of Mathematics: Faculty Publications
We consider a class of k-dimensional reaction-diusion epidemic models (k = 1; 2; • • • ) that are developed from autonomous ODE systems. We present a computational approach for the calculation and analysis of their basic reproduction numbers. Particularly, we apply matrix theory to study the relationship between the basic reproduction numbers of the PDE models and those of their underlying ODE models. We show that the basic reproduction numbers are the same for these PDE models and their associated ODE models in several important scenarios. We additionally provide two numerical examples to verify our analytical results.
Emerging From Content And Language Integrated Learning And English-Medium Instruction, Is Clil-Ised Emi The Next Trend Of Education?, Hengzhi Hu
Higher Learning Research Communications
Objectives: The text aims to present a comparison of Content and Language Integrated Learning (CLIL) and English-Medium Instruction (EMI), followed by a discussion of CLIL-ised EMI, a new educational phenomenon, regarding its feasibility in content-based bilingual programmes.
Method: The ideas presented in this paper are principally drawn from previous research and literature about CLIL and EMI, as well as from my personal experience with content-based bilingual education programmes.
Results: Although CLIL and EMI differ in nature, CLIL-ised EMI supplements traditional EMI, which has a single objective of content learning, with special attention to students’ needs, particularly their …
Research Data Management Practices And Challenges In Academic Libraries: A Comprehensive Review, Subaveerapandiyan A
Research Data Management Practices And Challenges In Academic Libraries: A Comprehensive Review, Subaveerapandiyan A
Library Philosophy and Practice (e-journal)
This comprehensive review article delves into the current landscape of research data management (RDM) practices and challenges faced by academic libraries across various regions. Utilizing a wide range of studies and data collected from different countries, this article aims to provide a comprehensive overview of the state of RDM services, the role of librarians, and the advancements in technology within academic libraries. The review explores the importance of RDM in supporting open science, data sharing, and reproducibility while also shedding light on areas that require further development and improvement.
Participatory Mapping Of Tree Equity, Preferences, And Environmental Justice In Portland, Or, Katharine Vezin Gregory
Participatory Mapping Of Tree Equity, Preferences, And Environmental Justice In Portland, Or, Katharine Vezin Gregory
Dissertations and Theses
Studies have shown that marginalized communities do not have the same access as more privileged groups to urban tree canopy cover due to historic and current processes of discrimination and disinvestment. This study explores the lived experiences, narratives, and values related to trees and greenspaces for residents of Portland, OR, through participatory mapping focus groups. It uses an environmental justice and urban political ecology framework to examine how values, lived experiences, and narratives compare for Portland residents across neighborhoods, socio-economic status, and racial or ethnic identity and how the changes that matter to residents can inform more just urban greening …
Community Supervision: Perspectives Of Probation And Parole Officers And Supervisors On Key Supervision Approaches And Policy Changes, Asianna Nelson
Community Supervision: Perspectives Of Probation And Parole Officers And Supervisors On Key Supervision Approaches And Policy Changes, Asianna Nelson
Dissertations and Theses
This study explores the differences across community supervision approaches in Oregon and how the implementation of state policies has influenced this field. Therefore, this study seeks to answer the following research questions: 1) How do POs and supervisors define their approach to community supervision? 2) How have POs and supervisors experienced shifts in state policy? Fourteen line staff and supervisors from seven Oregon probation and parole agencies were interviewed to answer these research questions. The findings suggest that most agencies are using evidence-based practices and implementing state policies. However, variation exists across the represented agencies in the experiences and perceptions …
The Processing Of Task-Relevant And Task-Irrelevant Information In Working Memory, Stephanie M. Saltzmann
The Processing Of Task-Relevant And Task-Irrelevant Information In Working Memory, Stephanie M. Saltzmann
LSU Doctoral Dissertations
Researchers have aimed to better understand the capacity limits and boundaries of working memory (WM) for decades. With a growing body of literature, researchers have started to direct their focus to identifying and understanding specific processes of WM. Information enters WM and is processed differently based on bottom-up (i.e., feature-driven) and top-down (i.e., task-driven) processes. Specifically, the current dissertation aimed to better understand how task-relevant and irrelevant information is maintained, selection, and prioritized in WM. In Chapter 1, we explored how the maintenance of task-relevant information in WM impacts the maintenance of task-irrelevant information. During a hybrid search task, participants …
Connecting The Optical Regime To The X-Ray In Neutron Star Low Mass X-Ray Binaries, Alexander B. Igl
Connecting The Optical Regime To The X-Ray In Neutron Star Low Mass X-Ray Binaries, Alexander B. Igl
LSU Doctoral Dissertations
Using Rossi X-Ray Timing Explorer and Otto Struve Telescope data of low mass X-ray binaries (LMXBs) Cyg X-2 and Sco X-1, the optical regime’s relationship to the X-ray was investigated through several angles. Discrete cross correlations using the optical and X-ray data revealed evidence of reprocessing in both datasets. These were more consistently present in Sco X-1, where both small and obvious features were seen at less than 4 s of optical lag. The size of these lags makes it likely that most of the reprocessing is taking place on the accretion disk. Parameterization of the Z tracks led to …
KCa2.2 (Kcnn2): A Physiologically And Therapeutically Important Potassium Channel, Mohammad Asikur Rahman, Razan Orfali, Nikita Dave, Elyn Lam, Nadeen Naguib, Young-Woo Nam, Miao Zhang
KCa2.2 (Kcnn2): A Physiologically And Therapeutically Important Potassium Channel, Mohammad Asikur Rahman, Razan Orfali, Nikita Dave, Elyn Lam, Nadeen Naguib, Young-Woo Nam, Miao Zhang
Pharmacy Faculty Articles and Research
One group of the K+ ion channels, the small-conductance Ca2+-activated potassium channels (KCa2.x, also known as SK channels family), is widely expressed in neurons as well as the heart, endothelial cells, etc. They are named small-conductance Ca2+-activated potassium channels (SK channels) due to their comparatively low single-channel conductance of about ~10 pS. These channels are insensitive to changes in membrane potential and are activated solely by rises in the intracellular Ca2+. According to the phylogenic research done on the KCa2.x channels family, there are three channels' subtypes: KCa2.1, K …
Influence Of Demographic And Clinical Characteristics On Circulating Gfap Levels In Mexican American And Non-Hispanic White Older Adults, Mitzi M. Gonzales, Gabriel A. Vela, Vinu Philip, Hector Trevino, Ashley Laroche, Chen-Pin Wang, Danielle M. Parent, Tiffany F. Kautz, Claudia L. Satizabal, Gladys E. Maestre
Influence Of Demographic And Clinical Characteristics On Circulating Gfap Levels In Mexican American And Non-Hispanic White Older Adults, Mitzi M. Gonzales, Gabriel A. Vela, Vinu Philip, Hector Trevino, Ashley Laroche, Chen-Pin Wang, Danielle M. Parent, Tiffany F. Kautz, Claudia L. Satizabal, Gladys E. Maestre
School of Medicine Publications
Background: Circulating levels of glial fibrillary acidic protein (GFAP), an intermediate filament protein of the astrocytic cytoskeleton and putative marker of reactive astrocytosis, increase with cerebral amyloid beta burden and associate with risk of incident all-cause and Alzheimer's disease (AD) dementia. However, further validation in diverse cohorts and evaluation of potential health disparities are necessary for broader generalization. The goal of the present study was to examine the associations between demographics, cardiovascular risk factors, and APOE ε4 status with serum GFAP levels among Mexican American and non-Hispanic white older adults across the continuum from cognitively unimpaired to AD dementia.
Method: …
Trastuzumab-Induced Interstitial Pneumonitis, Kimberly Errisuriz, Daniela Z. Bazan, Rene Verduzco Jr., Rosa Guedez
Trastuzumab-Induced Interstitial Pneumonitis, Kimberly Errisuriz, Daniela Z. Bazan, Rene Verduzco Jr., Rosa Guedez
School of Medicine Publications
Trastuzumab is a recombinant immunoglobulin G1 monoclonal antibody used to treat human epidermal growth factor receptor 2 (HER2) cancers. Trastuzumab-induced interstitial pneumonitis is a rare adverse effect reported in a few patients. Interstitial pneumonitis presents as symptoms of dyspnea, hypoxia, cough, and fever. If the patient is treated early, corticosteroids can slow or reverse the disease progression.
A 41-year-old woman presented with dyspnea and a dry cough three weeks after her third cycle of trastuzumab therapy for breast cancer. A diagnosis of trastuzumab-induced interstitial pneumonitis was made after multiple other disease processes were ruled out. The patient was started on …
Early Non-Response As A Predictor Of Later Non-Response To Antipsychotics In Schizophrenia: A Randomized Trial, Yujun Long, Qiongqiong Wu, Ye Yang, Jingda Cai, Jingmei Xiao, Yifeng Xu, Manli Huang, Ruiguo Zhang, Xijia Xu, Jian Hu, Zhifen Liu, Fang Liu, Yingjun Zheng, Huaqing Meng, Zhimin Wang, Yanqing Tang, Xueqin Song, Yunchun Chen, Xueyi Wang, Tiebang Liu, Xiaoli Wu, Maosheng Fang, Chunling Wan, Jingping Zhao, Renrong Wu
Early Non-Response As A Predictor Of Later Non-Response To Antipsychotics In Schizophrenia: A Randomized Trial, Yujun Long, Qiongqiong Wu, Ye Yang, Jingda Cai, Jingmei Xiao, Yifeng Xu, Manli Huang, Ruiguo Zhang, Xijia Xu, Jian Hu, Zhifen Liu, Fang Liu, Yingjun Zheng, Huaqing Meng, Zhimin Wang, Yanqing Tang, Xueqin Song, Yunchun Chen, Xueyi Wang, Tiebang Liu, Xiaoli Wu, Maosheng Fang, Chunling Wan, Jingping Zhao, Renrong Wu
Faculty, Staff and Student Publications
BACKGROUND: It remains a challenge to predict the long-term response to antipsychotics in patients with schizophrenia who do not respond at an early stage. This study aimed to investigate the optimal predictive cut-off value for early non-response that would better predict later non-response to antipsychotics in patients with schizophrenia.
METHODS: This multicenter, 8-week, open-label, randomized trial was conducted at 19 psychiatric centers throughout China. All enrolled participants were assigned to olanzapine, risperidone, amisulpride, or aripiprazole monotherapy for 8 weeks. The positive and negative syndrome scale (PANSS) was evaluated at baseline, week 2, week 4, and week 8. The main outcome …
Metastatic Infiltration Of Nervous Tissue And Periosteal Nerve Sprouting In Multiple Myeloma-Induced Bone Pain In Mice And Human, Marta Diaz-Delcastillo, Oana Palasca, Tim T Nemler, Didde M Thygesen, Norma A Chávez-Saldaña, Lizeth Y Ponce Gomez, Holly Evans, Rebecca E Andrews, Aritri Mandal, David Neves, Patrick Mehlen, James P Caruso, Patrick M Dougherty, Theodore J Price, Andrew Chantry, Michelle A Lawson, Thomas L Andersen, Juan M Jimenez-Andrade, Anne-Marie Heegaard
Metastatic Infiltration Of Nervous Tissue And Periosteal Nerve Sprouting In Multiple Myeloma-Induced Bone Pain In Mice And Human, Marta Diaz-Delcastillo, Oana Palasca, Tim T Nemler, Didde M Thygesen, Norma A Chávez-Saldaña, Lizeth Y Ponce Gomez, Holly Evans, Rebecca E Andrews, Aritri Mandal, David Neves, Patrick Mehlen, James P Caruso, Patrick M Dougherty, Theodore J Price, Andrew Chantry, Michelle A Lawson, Thomas L Andersen, Juan M Jimenez-Andrade, Anne-Marie Heegaard
Faculty, Staff and Student Publications
Multiple myeloma (MM) is a neoplasia of B plasma cells that often induces bone pain. However, the mechanisms underlying myeloma-induced bone pain (MIBP) are mostly unknown. Using a syngeneic MM mouse model, we show that periosteal nerve sprouting of calcitonin gene-related peptide (CGRP+) and growth associated protein 43 (GAP43+) fibers occurs concurrent to the onset of nociception and its blockade provides transient pain relief. MM patient samples also showed increased periosteal innervation. Mechanistically, we investigated MM induced gene expression changes in the dorsal root ganglia (DRG) innervating the MM-bearing bone of male mice and found alterations in pathways associated with …
Proteomics Analysis Of Plasma From Middle-Aged Adults Identifies Protein Markers Of Dementia Risk In Later Life, Keenan A Walker, Jingsha Chen, Liu Shi, Yunju Yang, Myriam Fornage, Pascal Schlosser, Morgan E Grams, Michael R Duggan, Zhongsheng Peng, Gabriela T Gomez, Adrienne Tin, Ron C Hoogeveen, Kevin J Sullivan, Peter Ganz, Joni V Lindbohm, Mika Kivimaki, Alejo J Nevado-Holgado, Noel Buckley, Rebecca F Gottesman, Thomas H Mosley, Eric Boerwinkle, Christie M Ballantyne, Josef Coresh
Proteomics Analysis Of Plasma From Middle-Aged Adults Identifies Protein Markers Of Dementia Risk In Later Life, Keenan A Walker, Jingsha Chen, Liu Shi, Yunju Yang, Myriam Fornage, Pascal Schlosser, Morgan E Grams, Michael R Duggan, Zhongsheng Peng, Gabriela T Gomez, Adrienne Tin, Ron C Hoogeveen, Kevin J Sullivan, Peter Ganz, Joni V Lindbohm, Mika Kivimaki, Alejo J Nevado-Holgado, Noel Buckley, Rebecca F Gottesman, Thomas H Mosley, Eric Boerwinkle, Christie M Ballantyne, Josef Coresh
Faculty, Staff and Student Publications
A diverse set of biological processes have been implicated in the pathophysiology of Alzheimer's disease (AD) and related dementias. However, there is limited understanding of the peripheral biological mechanisms relevant in the earliest phases of the disease. Here, we used a large-scale proteomics platform to examine the association of 4877 plasma proteins with 25-year dementia risk in 10,981 middle-aged adults. We found 32 dementia-associated plasma proteins that were involved in proteostasis, immunity, synaptic function, and extracellular matrix organization. We then replicated the association between 15 of these proteins and clinically relevant neurocognitive outcomes in two independent cohorts. We demonstrated that …
China Stroke Surveillance Report 2021
China Stroke Surveillance Report 2021
Faculty, Staff and Student Publications
Since 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China Stroke High-risk Population Screening and Intervention Program, an estimated 17.8 million [95% confidence interval (CI) 17.6–18.0 million] adults in China had experienced a stroke in 2020, with 3.4 million (95% CI 3.3–3.5 million) experiencing their first-ever stroke and another 2.3 million (95% CI 2.2–2.4 million) dying as a result. Additionally, approximately 12.5% (95% CI 12.4–12.5%) of stroke survivors were left disabled, as defined by a modified …
Metastatic Infiltration Of Nervous Tissue And Periosteal Nerve Sprouting In Multiple Myeloma-Induced Bone Pain In Mice And Human, Marta Diaz-Delcastillo, Oana Palasca, Tim T Nemler, Didde M Thygesen, Norma A Chávez-Saldaña, Lizeth Y Ponce Gomez, Holly Evans, Rebecca E Andrews, Aritri Mandal, David Neves, Patrick Mehlen, James P Caruso, Patrick M Dougherty, Theodore J Price, Andrew Chantry, Michelle A Lawson, Thomas L Andersen, Juan M Jimenez-Andrade, Anne-Marie Heegaard
Metastatic Infiltration Of Nervous Tissue And Periosteal Nerve Sprouting In Multiple Myeloma-Induced Bone Pain In Mice And Human, Marta Diaz-Delcastillo, Oana Palasca, Tim T Nemler, Didde M Thygesen, Norma A Chávez-Saldaña, Lizeth Y Ponce Gomez, Holly Evans, Rebecca E Andrews, Aritri Mandal, David Neves, Patrick Mehlen, James P Caruso, Patrick M Dougherty, Theodore J Price, Andrew Chantry, Michelle A Lawson, Thomas L Andersen, Juan M Jimenez-Andrade, Anne-Marie Heegaard
Faculty, Staff and Student Publications
Multiple myeloma (MM) is a neoplasia of B plasma cells that often induces bone pain. However, the mechanisms underlying myeloma-induced bone pain (MIBP) are mostly unknown. Using a syngeneic MM mouse model, we show that periosteal nerve sprouting of calcitonin gene-related peptide (CGRP+) and growth associated protein 43 (GAP43+) fibers occurs concurrent to the onset of nociception and its blockade provides transient pain relief. MM patient samples also showed increased periosteal innervation. Mechanistically, we investigated MM induced gene expression changes in the dorsal root ganglia (DRG) innervating the MM-bearing bone of male mice and found alterations in pathways associated with …
Addressing The Ocean-Climate Nexus In The Bbnj Agreement: Strategic Environmental Assessments, Human Rights And Equity In Ocean Science, Elisa Morgera, Kirsty Mcquaid, Giulia La Bianca, Holly Niner, Lynne Shannon, Mia Strand, Sian Rees, Kerry Howell, Bernadette Snow, Alana Malinde Sn Lancaster, Warwick Sauer
Addressing The Ocean-Climate Nexus In The Bbnj Agreement: Strategic Environmental Assessments, Human Rights And Equity In Ocean Science, Elisa Morgera, Kirsty Mcquaid, Giulia La Bianca, Holly Niner, Lynne Shannon, Mia Strand, Sian Rees, Kerry Howell, Bernadette Snow, Alana Malinde Sn Lancaster, Warwick Sauer
School of Biological and Marine Sciences
The Agreement on Marine Biodiversity of Areas beyond National Jurisdiction (BBNJ Agreement) opens a new path in international law towards addressing issues at the ocean-climate nexus, as well as considering implications for the protection of human rights and achieving equity among States in the context of ocean knowledge production and environmental management. Based on an interdisciplinary reflection, the new international obligations on strategic environmental assessments (SEAs), and new institutional arrangements, are identified as crucial avenues to addressing climate change mitigation and ensuring fair research partnerships, mutual capacity-building and technology co-development between the Global North and South. SEAs can also support …
A Thematic Exploration Of Patient And Radiation Therapist Solutions To Improve Comfort During Radiotherapy: A Qualitative Study, Simon Goldsworthy, Jos M. Latour, Shea Palmer, Helen A. Mcnair, Mary Cramp
A Thematic Exploration Of Patient And Radiation Therapist Solutions To Improve Comfort During Radiotherapy: A Qualitative Study, Simon Goldsworthy, Jos M. Latour, Shea Palmer, Helen A. Mcnair, Mary Cramp
School of Nursing and Midwifery
No abstract provided.
May Microbial Ecological Baseline Exist In Continental Groundwater?, Sining Zhong, Shungui Zhou, S Liu, Jiawen Wang, Chenyuan Dang, Qian Chen, Jinyun Hu, Shanqing Yang, Chunfang Deng, Wenpeng Li, J Liu, Alistair G.L. Borthwick, Jinren Ni
May Microbial Ecological Baseline Exist In Continental Groundwater?, Sining Zhong, Shungui Zhou, S Liu, Jiawen Wang, Chenyuan Dang, Qian Chen, Jinyun Hu, Shanqing Yang, Chunfang Deng, Wenpeng Li, J Liu, Alistair G.L. Borthwick, Jinren Ni
School of Engineering, Computing and Mathematics
Background Microbes constitute almost the entire biological community in subsurface groundwater and play an important role in ecological evolution and global biogeochemical cycles. Ecological baseline as a fundamental reference with less human interference has been investigated in surface ecosystems such as soils, rivers, and ocean, but the existence of groundwater microbial ecological baseline (GMEB) is still an open question so far. Results Based on high-throughput sequencing information derived from national monitoring of 733 newly constructed wells, we find that bacterial communities in pristine groundwater exhibit a significant lateral diversity gradient and gradually approach the topsoil microbial latitudinal diversity gradient with …