Digital Commons Network^™

Exerting The Think Tank Role Of Academic Divisions And Serving The Needs Of National Dual Carbon Strategy—Major Consultancy Project Of Carbon Neutrality By Cas Academic Divisions, Jianming Gong, Hejun Yu, Xiaonan Duan, Jiansheng Qu, Jingjing Zeng, Chen Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The main responsibility of the national strategic scientific and technological force is to focus on national strategic needs, refine key scientific problems in basic research, and gather resources to conduct original and leading scientific and technological research. The dual carbon goal is an internal requirement to implement the new development concept, construct a new development pattern, and promote high-quality development. It is a major strategic decision made by the Central Committee of the Communist Party of China in current domestic and international situations. We take the carbon neutrality major consulting project, Chinese Academy of Sciences (CAS), as a specific case, …

Technological Innovation And Development In China’S Banking Industry: Problems And Countermeasures, Chuhan Zhang, Jichang Dong, Zhi Dong, Xiuting Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

With the deep integration of science and technology into industrial transformation, the technological innovation in China’s banking industry has reached a new level with growing capacity for innovation, relying on the “dual-wheel” innovation-driven development of business and technology. However, there are still problems and challenges for the technological innovation and development in China’s banking industry, such as concerns about the safety of key information infrastructure and high dependence on foreign sources for core technology. It is urgent to build a relatively complete, self-reliant, stable, and secure banking technology system. This study reviews the development process and main achievements of technological …

Devoting Continuous Efforts To Innovations And Development Of Ruminant Livestock Life-Cycle Nutrition Program, Zhixiong He, Zhaomin Hu, Hongsheng Wang, Jinzhen Jiao, Xuefeng Han, Yong Liu, Shaoxun Tang, Chuanshe Zhou, Min Wang, Zhiliang Tan

Bulletin of Chinese Academy of Sciences (Chinese Version)

Ruminant livestock such as cattle and sheep can provide high-quality beef, mutton and milk, which are high-quality protein sources meeting the increasingly diverse food consumption needs for human being. Developing high-quality herbivorous animal husbandry is a concrete practice of practicing the “Greater Food” approach. The precise supply of forages and concentrates meeting the requirements of all nutrients in the whole life cycle is vital for cost saving and efficiency increasing of ruminant livestock industry, which is an important way to high-quality development. The whole life cycle nutrition is developed on the basis of traditional ruminant nutrition and new technologies made …

Xianghe Integrated Observatory Of Climate And Environment, Institute Of Atmospheric Physics, Chinese Academy Of Sciences

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

2023 Issue 7 Content

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Information Literacy In The Sciences: Strategies For Engaging Undergraduate Learners In The Classroom, Justin Savage, Siobhan Mccarthy

University Libraries Scholarship and Creative Works

No abstract provided.

Knowledge Culture And Librarian's Productivity In University Libraries In South-South, Nigeria, Eniekebi Ejiroghene

Library Philosophy and Practice (e-journal)

This work is set to ascertain Knowledge Culture and Librarians’ Productivity in University Libraries in South-South, Nigeria. A descriptive survey design was adopted for the study. The study population was 132 Librarians working in the Federal, State and Privately-owned University libraries in South-South Nigeria. The entire population was used for the study as it was manageable. A self-designed questionnaire was used to collect data on knowledge culture and Librarians productivity. Means were used to answer the Research questions while the Pearson Product Moment Correlation coefficient was used to test the hypotheses. Results from the study show that University Librarians adopted …

Current Developmental Challenges In Nepal: How Can The Diaspora Help?, Ambika P. Adhikari

Himalayan Research Papers Archive

Nepal now enjoys a unique opportunity to positively transform the country’s economy and society. The economic activities fueled by remittance, supported by foreign aid, and aided by domestic economic activities such as tourism, trade, and services, including start-ups, are helping increase individual incomes. However, the earnings from remittances, which measure to about 25% of Nepal’s GDP, are spent on consumer goods and not on investments that can generate employment and raise the standards of living. The foreign aid is often donor driven and also not always well managed and wisely spent on national priorities. Further, it is frequently marred by …

Hsc Connects Newsletter - July 20, 2023, Unm Hsc Communications

HSC Connects Newsletters

Weekly newsletter of the UNM Health Sciences Center.

Assessing The Performance Of Exchange-Correlation Functionals On Lattice Constants Of Binary Solids At Room Temperature Within The Quasiharmonic Approximation, Xiaofei Shao, Peitao Liu, Cesare Franchini, Yi Xia, Jiangang He

Mechanical and Materials Engineering Faculty Publications and Presentations

The exchange-correlation functional is at the core of density functional theory (DFT) and determines the accuracy of DFT in describing the interactions among electrons/ions in solids and molecules. The strongly constrained and appropriately normed functional (SCAN) and its derivatives, regularized SCAN (rSCAN) and regularized-restored SCAN (r2SCAN), are particularly promising due to their remarkable overall accuracy in the description of various properties while retaining a high computational efficiency as compared to hybrid functionals. However, an exhaustive assessment on the performance of these functionals in predicting the finite-temperature lattice constant of solids is still lacking. Here, we systematically study the room-temperature lattice …

Mechanisms Of Fibrillar Aggregation Of The Lens Small Heat Shock Proteins, Αa- And Αb-Crystallin, Russell James Mcfarland

Dissertations and Theses

The protein αB-crystallin represents the archetypical small heat-shock protein (sHSP), and together with αA-crystallin makes up the primary chaperone system in the eye lens, where they play a critical role in maintaining proteostasis. To achieve transparency, the lens undergoes a loss of organelles and both protein turnover halts, requiring that proteins remain functional for long periods of time as they accumulate chemical damage. The α-crystallins are highly abundant in the lens to stabilize proteostasis for multiple decades. Over time though, the small heat-shock proteins become overwhelmed by a high burden of destabilized clients and their own accumulated chemical damage. Mechanistic …

A Hybrid Metaheuristic And Computer Vision Approach To Closed-Loop Calibration Of Fused Deposition Modeling 3d Printers, Graig S. Ganitano, Shay V. Wallace, Benji Maruyama, Gilbert L. Peterson

Faculty Publications

Fused deposition modeling (FDM) is one of the most popular additive manufacturing (AM) technologies for reasons including its low cost and versatility. However, like many AM technologies, the FDM process is sensitive to changes in the feedstock material. Utilizing a new feedstock requires a time-consuming trial-and-error process to identify optimal settings for a large number of process parameters. The experience required to efficiently calibrate a printer to a new feedstock acts as a barrier to entry. To enable greater accessibility to non-expert users, this paper presents the first system for autonomous calibration of low-cost FDM 3D printers that demonstrates optimizing …

Perspectives In Immunotherapy: Meeting Report From Immunotherapy Bridge (Naples, November 30th-December 1st, 2022), Paolo A Ascierto, Nathan Singh, Et Al.

2020-Current year OA Pubs

The discovery and development of novel treatments that harness the patient's immune system and prevent immune escape has dramatically improved outcomes for patients across cancer types. However, not all patients respond to immunotherapy, acquired resistance remains a challenge, and responses are poor in certain tumors which are considered to be immunologically cold. This has led to the need for new immunotherapy-based approaches, including adoptive cell transfer (ACT), therapeutic vaccines, and novel immune checkpoint inhibitors. These new approaches are focused on patients with an inadequate response to current treatments, with emerging evidence of improved responses in various cancers with new immunotherapy …

Structures Of Channelrhodopsin Paralogs In Peptidiscs Explain Their Contrasting K+ And Na+ Selectivities, Takefumi Morizumi, Kyumhyuk Kim, Hai Li, Elena G Govorunova, Oleg A Sineshchekov, Lei Zheng, Ana-Nicoleta Bondar, Azam Askari, Leonid S Brown, John L Spudich, Oliver P Ernst

Faculty, Staff and Student Publications

Kalium channelrhodopsin 1 from Hyphochytrium catenoides (HcKCR1) is a light-gated channel used for optogenetic silencing of mammalian neurons. It selects K+ over Na+ in the absence of the canonical tetrameric K+ selectivity filter found universally in voltage- and ligand-gated channels. The genome of H. catenoides also encodes a highly homologous cation channelrhodopsin (HcCCR), a Na+ channel with >100-fold larger Na+ to K+ permeability ratio. Here, we use cryo-electron microscopy to determine atomic structures of these two channels embedded in peptidiscs to elucidate structural foundations of their dramatically different cation selectivity. Together with structure-guided mutagenesis, we show …

Measuring And Enhancing The Ionic Conductivity Of Chloroaluminate Electrolytes For Al-Ion Batteries, Anthony J Lucio, Iwan Sumarlan, Elena Bulmer, Igor Efimov, Stephen Viles, Christopher J Zaleski

Faculty, Staff and Student Publications

At the core of the aluminum (Al) ion battery is the liquid electrolyte, which governs the underlying chemistry. Optimizing the rheological properties of the electrolyte is critical to advance the state of the art. In the present work, the chloroaluminate electrolyte is made by reacting AlCl3 with a recently reported acetamidinium chloride (Acet-Cl) salt in an effort to make a more performant liquid electrolyte. Using AlCl3:Acet-Cl as a model electrolyte, we build on our previous work, which established a new method for extracting the ionic conductivity from fitting voltammetric data, and in this contribution, we validate the method across a …

Multi-Campaign Ship And Aircraft Observations Of Marine Cloud Condensation Nuclei And Droplet Concentrations, Francesca Gallo, Claire E Robinson, Amy Jo Scarino, Taylor J Shingler, Michael A Shook, Kenneth L Thornhill, Elizabeth B Wiggins, Edward L Winstead, Luke D Ziemba, Scott Chambers, Alastair Williams, Ruhi S Humphries, Melita D Keywood, Jason P Ward, Luke Cravigan, Ian M Mcrobert, Connor Flynn, Gourihar R Kulkarni, Lynn M Russell, Gregory C Roberts, Greg M Mcfarquhar, Athanasios Nenes, Sarah F Woods, Jeffery S Reid, Jennifer Small-Griswold, Sarah Brooks, Simon Kirschler, Christianne Voigt, Jian Wang, David J Delene, Patricia K Quinn, Richard H Moore

Faculty, Staff and Student Publications

In-situ marine cloud droplet number concentrations (CDNCs), cloud condensation nuclei (CCN), and CCN proxies, based on particle sizes and optical properties, are accumulated from seven field campaigns: ACTIVATE; NAAMES; CAMP2EX; ORACLES; SOCRATES; MARCUS; and CAPRICORN2. Each campaign involves aircraft measurements, ship-based measurements, or both. Measurements collected over the North and Central Atlantic, Indo-Pacific, and Southern Oceans, represent a range of clean to polluted conditions in various climate regimes. With the extensive range of environmental conditions sampled, this data collection is ideal for testing satellite remote detection methods of CDNC and CCN in marine environments. Remote measurement methods are vital to …

Study Of Polytopic Membrane Protein Topological Organization As A Function Of Membrane Lipid Composition, Oleg A Sineshchekov, Ana-Nicoleta Bondar, Azam Askari, Leonid S Brown, John L Spudich, Oliver P Ernst

Faculty, Staff and Student Publications

Kalium channelrhodopsin 1 from Hyphochytrium catenoides (HcKCR1) is a light-gated channel used for optogenetic silencing of mammalian neurons. It selects K+ over Na+ in the absence of the canonical tetrameric K+ selectivity filter found universally in voltage- and ligand-gated channels. The genome of H. catenoides also encodes a highly homologous cation channelrhodopsin (HcCCR), a Na+ channel with >100-fold larger Na+ to K+ permeability ratio. Here, we use cryo-electron microscopy to determine atomic structures of these two channels embedded in peptidiscs to elucidate structural foundations of their dramatically different cation selectivity. Together with structure-guided mutagenesis, we show that K+ versus Na+ …

Asian Americans In Stem Are Not A Monolith, Zer Vue, Chia Vang, Neng Vue, Vijayvardhan Kamalumpundi, Taylor Barongan, Sunny Huang, Mein Vue, Nancy Vang, Jianqiang Shao, Coohleenann Coombes, Prasanna Katti, Kaihua Liu, Kailee Yoshimura, Michelle Biete, Dao-Fu Dai, Mark A Phillips, Richard R Behringer

Faculty, Staff and Student Publications

Despite tremendous diversity, Asian Americans in STEM are grouped and viewed as a homogeneous monolith, facing stereotypes and disparities. We propose solutions that include disaggregating the Asian American grouping and recognizing the diverse individual ethnic subgroups that comprise Americans of Asian ancestry to implement change within the STEM field.

A Novel Statistical Method For Decontaminating T-Cell Receptor Sequencing Data, Ruoxing Li, Mehmet Altan, Alexandre Reuben, Ruitao Lin, John V Heymach, Runzhe Chen, Shawna Hubert, Jianjun Zhang, Ziyi Li

Faculty, Staff and Student Publications

The T-cell receptor (TCR) repertoire is highly diverse among the population and plays an essential role in initiating multiple immune processes. TCR sequencing (TCR-seq) has been developed to profile the T cell repertoire. Similar to other high-throughput experiments, contamination can happen during several steps of TCR-seq, including sample collection, preparation and sequencing. Such contamination creates artifacts in the data, leading to inaccurate or even biased results. Most existing methods assume 'clean' TCR-seq data as the starting point with no ability to handle data contamination. Here, we develop a novel statistical model to systematically detect and remove contamination in TCR-seq data. …

Competencies For Psychology Practice In Pediatric Palliative Care, Aimee K Hildenbrand, Melissa K Cousino, Meghan L Marsac, Jill Majeski, Karen Wohlheiter, Rachel A Kentor

Faculty, Staff and Students Publications

Objective: Pediatric psychologists have unique expertise to contribute to the care of youth with serious illnesses yet are not routinely integrated into pediatric palliative care (PPC) teams. To better define the role and unique skillset of psychologists practicing in PPC, support their systematic inclusion as part of PPC teams, and advance trainee knowledge of PPC principles and skills, the PPC Psychology Working Group sought to develop core competencies for psychologists in this subspecialty.

Methods: A Working Group of pediatric psychologists with expertise in PPC met monthly to review literature and existing competencies in pediatrics, pediatric and subspecialty psychology, adult palliative …

Numerical Analysis Of The Performance Of A Three-Bladed Vertical-Axis Turbine With Active Pitch Control Using A Coupled Unsteady Reynolds-Averaged Navier-Stokes And Actuator Line Model, Rui Wen Zhao, Angus C.W. Creech, Ye Li, Vengatesan Venugopal, Alistair G.L. Borthwick

School of Engineering, Computing and Mathematics

In this paper, we present a numerical model of a vertical-axis turbine (VAT) with active-pitch torque control. The model is based upon the Wind and Tidal Turbine Embedded Simulator (WATTES) and WATTES-V turbine realisations in conjunction with the actuator line method (ALM), and uses OpenFOAM to solve the unsteady Reynolds-averaged Navier-Stokes (URANS) equations with two-equation k - ε turbulence closure. Our novel pitch-controlled system is based on an even pressure drop across the entire rotor to mitigate against dynamic stall at low tip speed ratio. The numerical model is validated against experimental measurements and alternative numerical predictions of the hydrodynamic …

Bayesian Multivariate Nonlinear State Space Copula Models, A Kreuzer, L Dalla Valle, C Czado

School of Engineering, Computing and Mathematics

A novel flexible class of multivariate nonlinear non-Gaussian state space models, based on copulas, is proposed. Specifically, it is assumed that the observation equation and the state equation are defined by copula families that are not necessarily equal. Inference is performed within the Bayesian framework, using the Hamiltonian Monte Carlo method. Simulation studies show that the proposed copula-based approach is extremely flexible, since it is able to describe a wide range of dependence structures and, at the same time, allows us to deal with missing data. The application to atmospheric pollutant measurement data shows that the approach is suitable for …

Acknowledgments

D.U.Quark

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Table Of Contents

D.U.Quark

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Mend - Complete Issue, V. 1, Mend Journal

Mend

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Editors - Mend, V.1, Mend Journal

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Artists - Mend, V. 1, Mend Journal

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The Card, Vicki Hicks

Mend

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