Digital Commons Network^™

Physics-Informed Neural Network Solution Of The 2d Helmholtz Equation With A Gaussian Source, Theodoros Panagiotakopoulos, Chris Velissaris, Aristotelis Nikolaos Rapsomanikis

Faculty Scholarship and Creative Works

We present a physics-informed neural network (PINN) framework for solving the complex-valued two-dimensional Helmholtz equation with a localized Gaussian source and spatially varying permittivity. Starting from Maxwell’s equations, the frequency-domain scalar Helmholtz formulation under transverse electric (TE) polarization is derived and enforced directly within the neural network loss function. The model employs a sinusoidal representation network (SIREN) architecture to capture the oscillatory nature of wave solutions and incorporates the Sommerfeld radiation condition to impose open boundary conditions. Training is performed using a hybrid collocation strategy combined with a two-stage optimization procedure consisting of Adam followed by L-BFGS. Numerical experiments in …

Effective Strategies For Sustaining Massage Small Businesses Beyond 5 Years, Steven Brian Glover

Walden Dissertations and Doctoral Studies

Ineffective business strategies can lead to premature closure. Small business owners who struggle to develop long-term strategies may experience failure as a result. Grounded in the resource-based view and dynamic capabilities theory, the purpose of this qualitative pragmatic inquiry research project was to identify and explore practical strategies used by massage therapy small business owners to sustain their businesses for more than 5 years. The participants were 10 massage therapy small business owners who had sustained their businesses for more than 5 years. Data were collected through semistructured interviews, business documents, and public records. Through thematic analysis, six themes were …

Unh Speech And Language Therapy Collaboration Improves Communication For Client With Aphasia, Aaron Sanborn

UNH Today Archive

No abstract provided.

Co-Occurrence Of Transcriptionally Distinct Persister Cell States Underpins Neoadjuvant Therapy Resistance In Triple-Negative Breast Cancer, Yu Zhang, Fatemeh Ahmadi Moughari, Ioanna Mavrommati, Nora J Doleschall, Kate Moore, Gareth Muirhead, Ram Rajaram Srinivasan, Ping Gong, Jonathan T Lei, Amy Fleming, Hwei Minn Khoo, Naomi Guppy, Gabrielle Elshtein, Mohammed Inayatullah, Vijay K Tiwari, Lacey E Dobrolecki, Michael T Lewis, Syed Haider, Rachael Natrajan

Faculty, Staff and Students Publications

Background

Although the addition of neoadjuvant immune checkpoint blockade to chemotherapy has improved patient outcome in early triple‑negative breast cancer (TNBC), some patients continue to have poor disease outcomes.

Methods

To characterise neoadjuvant chemotherapy (NAC) resistant cell populations that persist post-NAC, we created a high-resolution single-cell atlas of 129,433 cells from fourteen TNBC patient-derived xenograft (PDX) models with residual disease post-NAC. We identified transcriptionally distinct cancer subpopulations or cell states using unsupervised clustering and characterised‑ their regulatory network as well as clinical associations with treatment response, metastatic progression and survival. Findings were validated using multiple independent TNBC cohorts.

Results

Four …

Contributing Factors Of Contralateral Breast Cancer In Patients With Brca Mutation (On-Brca Ii Study, Korea-Bsg 11), Seon-Hi Shin, Sung Gwe Ahn, Jai Min Ryu, Sae Byul Lee, Hyung Seok Park, Eun-Shin Lee, Janghee Lee, Byeongju Kang, Sanghwa Kim, Eun Young Kim, Young-Joon Kang, Sun Young Min, Moohyun Lee, Se-Kang Kim, Hong-Kyu Kim, Chihwan David Cha

Faculty, Staff and Students Publications

Background: The cumulative risk of contralateral breast cancer (CBC) in BRCA1/2 carriers is remarkably higher than in non-carriers. This study aimed to investigate the clinicopathological predictors associated with the risk of metachronous CBC among breast cancer patients with BRCA1/2 mutations using correspondence analysis.

Methods: This retrospective study included patients who underwent BRCA testing between January 2008 and December 2018. The inclusion criterion was patients being between 20 and 80-years-old with invasive breast cancer (pT1-3, N0-3). We performed univariate and multivariate survival analyses to assess the risks associated with BRCA mutations, and conducted correspondence analysis to identify contributing factors for CBC …

The Use Of Radiofrequency In The Treatment Of Erectile Dysfunction, Sarah Ponce, Nikola Rakic, Beatriz Hernandez, Mohit Khera

Faculty, Staff and Students Publications

No abstract provided.

Bi-Allelic Variants In Ap5z1 And Ap5b1 Lead To Retinal Degeneration, Hafiz Muhammad Jafar Hussain, Meng Wang, Paul Yang, Behnoosh Tasharrofi, Yumei Li, Rebecca Lynn Clark, Emma Fale-Olsen, Grace Waldow, Mohammad Keramatipour, Mostafa Asadollahi, Mark E Pennesi, Rui Chen

Faculty, Staff and Students Publications

Inherited retinal diseases (IRDs) comprise a diverse group of disorders that frequently lead to progressive vision impairment and blindness. Despite advances in genetic testing, a significant number of IRD cases remain genetically unsolved, often due to unidentified disease-associated genes or variants. This study reports additional cases for the newly discovered IRD genes of the AP-5 complex. A comprehensive ophthalmological evaluation was performed for all patients, including retinal imaging (multimodal imaging), visual field testing, and electroretinogram (ERG) testing. Whole-genome and -exome sequencing (WGS and WES) were performed for clinically unsolved IRD patients, and data were analyzed to identify underlying causal variants. …

Evapecognition: An 18-Year Dataset Of Great Ape Cognition, Alejandro Sánchez-Amaro, Sonja J Ebel Van Wijk, Carin Molenaar, Akzira Abuova, Lizbeth Mujica-Manrique, Sarah M Leisterer-Peoples, Bret Beheim, Luke Maurits, Anna Albiach-Serrano, Matthias Allritz, Nazli Altınok, Federica Amici, Alice Mi Auersperg, Filippo Aureli, Elisa Bandini, Jochen Barth, Leïla Benziad, Bettina E Bläsing, Manuel Bohn, Marie Bourjade, Juliane Bräuer, Marie-Hélène Broihanne, Sarah F Brosnan, Nereida Bueno-Guerra, Thomas Bugnyar, David Buttelmann, Frances Buttelmann, Trix Cacchione, Malinda Carpenter, Fernando Colmenares, Catherine Crockford, Katherine A Cronin, África De Las Heras, Arianna De Marco, Sarah E Detroy, Valérie Dufour, Shona Duguid, Robin I M Dunbar, Johanna Eckert, Jan M Engelmann, Joel Fagot, Julia Fischer, Sofia Ingrid Fredrika Forss, Martina Funk, György Gergely, Julia R Greenberg, Johannes Großmann, Sebastian Grüneisen, Marta Halina, Daniel Hanus, Sarah R Heilbronner, Christophe Heintz, Robert Hepach, Esther Herrmann, Satoshi Hirata, Alenka Hribar, Gabriele Janzen, Juliane Kaminski, Patricia Kanngiesser, Fumihiro Kano, Katharina C Kirchhofer, Hagen Knofe, Kathrin S Kopp, Christopher Krupenye, Isabelle Barbara Laumer, Stephen C Levinson, Ulf Liszkowski, Héctor M Manrique, Gema Martin-Ordas, Emma Suvi Mcewen, Richard T Moore, Enric Munar, Marcos Nadal, Christian Nawroth, Suska Nolte, Marie Pelé, Patrizia Potì, Hannes Rakoczy, Julia Riedel, Amélie Romain, Federico Rossano, Yvan I Russell, Gloria Sabbatini, Marie Schäfer, Marina Scheumann, Martin Schmelz, Benjamin Schmid, Vanesa Schmitt, Carla Sebastián-Enesco, Amanda Madeleine Seed, Chikako Suda-King, Tibor Tauzin, Sebastian Tempelmann, Claudio Tennie, Valentina Truppa, Jana Uher, Amrisha Vaish, Edwin J C Van Leeuwen, Elisabetta M Visalberghi, Christoph J Völter, Victoria Vonau, Claudia A F Wascher, Roman M Wittig, Wouter Wolf, Michael Tomasello, Katja Liebal, Josep Call, Daniel B M Haun

Faculty, Staff and Students Publications

The study of great ape cognition offers insights into the evolutionary origins of human intelligence, but is hindered by small sample sizes and restricted access to data. To address this, we present the EVApeCognition Dataset, a publicly available resource comprising 262 experimental datasets from 150 scientific publications from the Wolfgang Köhler Primate Research Center (2004-2021) in Leipzig, Germany. Eighty-one apes participated in 150 studies, with a majority (N = 78) participating in more than one study. Publication of the dataset aims to make these unique datasets accessible for future meta-analyses and correlational analyses, helping us better understand how our great …

Tracking Hiv Through Wastewater: Ethical Considerations In Public Health Surveillance, Faith E Fletcher, Olive R Pertuit, Catherine Troisi, Jelani Kerr, Dakotah Kinsella, Grace Elizabeth White, Steven Vargas, Anthony Maresso, Thomas P Giordano

Faculty, Staff and Students Publications

Ending the HIV epidemic requires timely identification of new HIV infections and promptly linking patients to high-quality care. Innovative methods are needed to capture real-time HIV incidence data to more effectively identify persons in need of HIV care access. Emerging advancements in wastewater surveillance (WWS) offer the potential to identify geographic areas with elevated prevalence of detectable viral loads among people who are undiagnosed or no longer receiving care, enabling more targeted interventions to reduce HIV transmission. The introduction of new public health technologies requires balancing potential risks with the significant clinical and population-level benefits of decreasing the number of …

Identifying Major Sources Of Leptospira Interrogans In San Juan Bay And Río Grande De Loíza Estuaries Of Puerto Rico, Logan Mccullers, Dave Bachoon

Biology Theses

This study evaluated the presence of pathogenic Leptospira interrogans, potential carriers, and environmental factors influencing their occurrence in the San Juan Bay Estuary (SJBE) and Río Grande de Loíza (RGDL) watersheds of Puerto Rico from 2024–2025. Detection of this pathogen from water samples was performed using the lipL32 PCR assay. The likely hosts of L. interrogans were determined using fecal source tracking (FST) assays for human (HF-183), canine (BacCan-UCD), equine (HoF597), and rat mitochondrial DNA NADH dehydrogenase subunit 2 gene (RatMt) markers. In 2024, 91 samples were collected (March: 50; June: 41), and in 2025, 124 samples were collected …

Preparing Nursing Students To Support Healthy Work Environments By Teaching Stress First Aid, Veronica Betts, Courtney E. Reinisch, Brenda Marshall

Creating Healthy Work Environments (CHWE)

Stress First Aid (SFA), is an evidence-based education program developed to address stress experienced by front line servicemen in the US military. This leadership and peer support model promotes mental wellness by teaching specific coping skills that build resilience an individual can access in times of stress (NJ NEW, 2025). The SFA training has been demonstrated to decrease stress in nursing staff. Nursing faculty have an ethical responsibility to provide education that promotes wellbeing, resilience, supporting prelicensure nursing students with skills to successfully transition into their roles as nurses (Sinmileoluwa et al., 2020).

Including SFA in nursing education prepares future …

Concurrent Superior Mesenteric And Splenic Vein Thrombosis In A Prothrombin G20210a Carrier: Radiologic Evolution And Resolution On Apixaban, Christopher M. Ahmad, Rae-Anne Kastle, Niki Gharavi Alkhansari, Phil T. Sheridan, Samir Dalia

Student Publications

Splanchnic venous thrombosis (SVT) is an uncommon vascular condition that may occur in association with liver disease, malignancy, or intra-abdominal inflammatory processes. In cases where these conditions are absent, and SVT occurs as a primary disease process, an underlying thrombophilic predisposition should be considered. Concurrent involvement of the superior mesenteric and splenic veins in this context is uncommon and may suggest an inherited prothrombotic tendency. We describe a 76-year-old man with a known heterozygous prothrombin G20210A mutation who presented with several days of abdominal discomfort and was found to have non-occlusive thrombosis of the superior mesenteric vein extending into the …

Cognitive Warfare And The Changing Character Of Engagement: A Neurostrategic Perspective, James Giordano

Strategic Insights

This commentary explains how cognitive warfare goes beyond traditional information and psychological operations. Instead of trying to change what people think, it focuses on how they think - such as shaping perception, judgment, and decision-making using advances in neuroscience, artificial intelligence, and data. Dr. Giordano argues that the human mind is becoming a key battleground in modern conflict. These approaches can affect individuals and societies by weakening decision-making, trust, and cohesion. As a result, conflict is increasingly defined by the ability to influence thinking and behavior, raising important strategic and ethical questions for future military operations.

Epigenome-Wide Association Study Of Blood Proteome In The Atherosclerosis Risk In Communities Study, Yang Li, Aditya Surapaneni, Zulema Rodriguez-Hernandez, Pascal Schlosser, Eugene P Rhee, Eric Boerwinkle, Bing Yu, Megan L Grove, Kelly V Ruggles, Josef Coresh, Morgan Grams

Faculty, Staff and Student Publications

Characterizing the relationship between DNA methylation and circulating proteins is critical to understanding the epigenetic regulation of the human plasma proteome. Here, we performed an epigenome-wide association study of 5,032 circulating proteins in 1,449 White and 315 Black participants from the Atherosclerosis Risk in Communities cohort. We identified 12,500 significant protein quantitative trait methylation (pQTM)-protein associations involving 1,647 proteins. Among 7,796 unique pQTMs, 14.7% were classified as cis-pQTMs, which were enriched for fundamental cellular processes, whereas trans-pQTMs were predominantly linked to immune-related functions. Trans-pQTMs also exhibited stronger associations with demographic, lifestyle, and clinical traits as compared with cis-pQTMs. We identified …

Identifying Factors Influencing Nurses' Decision To Remain In The Clinical Setting, Shoug Alsobhi, Soud Sbehat, Naomi Tuifao

Creating Healthy Work Environments (CHWE)

Background: The healthcare industry, especially in clinical settings, is heavily reliant on the availability of skilled nursing professionals. Despite the increasing demand for nurses, many clinical settings face challenges related to nurse retention. High turnover rates not only affect the quality of care but also result in financial and operational inefficiencies for healthcare institutions. Understanding the factors that influence a nurse’s decision to remain in the clinical setting is critical to addressing these issues and improving retention strategies.

Aim: The aim of this study is to identify and analyze the key factors influencing nurses' decisions to remain in the clinical …

Empowering Well-Being Advocates: Activating Peer Supporters To Build A Well-Being Focused Team, Joel R. Anderson

Creating Healthy Work Environments (CHWE)

Background: A large academic health system developed a Team Well-Being Advocate (TWA) training curriculum emphasizing proactive peer support and strategies to address stress injury, unnecessary stressors, and workplace challenges known to erode healthy work environments. Grounded in the research of Dr. Richard Westphal on the stress continuum and Dr. Peggy Plews-Ogan on wisdom practices, the program integrates structured peer support with team-specific data to guide evidence-based well-being interventions at the microsystem level.

Purpose: To describe the design and implementation of a scalable, peer-driven model that promotes healthy work environments across an academic healthcare system using data to identify and reduce …

A Commentary On Hong And Thoroughgood (2025): Exclusion Signaling As A Complementary Mechanism In Third-Party Reactions To Witnessed Gratitude, Farzaneh Fouladi, S. R. Aurora

Management Faculty Publications

No abstract provided.

Bridging Libraries And Classrooms: Co-Teaching For Student Success, Joy Urbina, Isabel Baca

Librarian Conference Presentations

An instructional librarian and writing professor describe their collaborative approach to co-teaching. Learn how integrating information literacy with writing instruction strengthens students' critical thinking and research skills and discover practical strategies from this successful cross-disciplinary partnership.

2026 Walk, Run, Hike 6.9 Miles Challenge, Alison Coleman

UNH Cooperative Extension

No abstract provided.

Exploring Healthcare Career Pathways: Survey Findings From The Unmc High School Alliance Program, Jana L. Wardian Phd, Rachael Jaixen, Jaynie Bird, Heidi Kaschke

Innovations in Health Sciences Education Journal

The ongoing demand for a well-prepared and adequately staffed healthcare workforce in the United States highlights the value of effective educational pipeline programs. The University of Nebraska Medical Center (UNMC) High School Alliance (HSA) was created as an immersive, academic enrichment initiative to expose motivated high school students from a range of educational and socioeconomic backgrounds to health professions, with the long-term aim of strengthening the healthcare workforce in Nebraska. This article evaluates the design, curriculum, and measurable impact of the UNMC HSA over its 16-year history. Students participate daily throughout the school year, engaging in courses such as patient …

Aiw26s: Applied Llms, Chengjie Zheng

Paul English Applied Artificial Intelligence (AI) Institute Publications

This workshop introduces the concept of applied large language models (LLMs), focusing on how users can move from simple prompt-based interaction to building structured, repeatable AI-driven workflows. Participants explore how AI enables faster prototyping, lowers barriers to entry, and expands who can participate in building technology. Through a hands-on demonstration, attendees learn how to transform raw inputs into meaningful outputs such as summaries, key concepts, and actionable steps. The session emphasizes the importance of clear problem definition, iterative refinement, and critical evaluation when working with AI systems.

Critical Minerals In A Critical Time, Parker J. Peterson, Sophia Budge, Brooks Miner

FHSS Mentored Research Conference

This study evaluates U.S. positioning in rare earth mineral (REM) supply chains by analyzing global mine concentrations and trade alignments. While the U.S. ranks second in production, its critical vulnerability lies in processing, where China controls 60–80% of global capacity. Strategic investment and allied partnerships are essential for long-term supply chain resilience.

Where's Our Water? Invasive Saltcedar's Thirsty Trek Across The Shoreline Of Lake Mead, Mia R. Morgan, Joseph Penrod, Ruth Kerry

FHSS Mentored Research Conference

The prolonged megadrought in Southern Nevada has exposed thousands of acres of former lakebed at Lake Mead, creating an expanding frontier for the invasive shrub Tamarix ramosissima, commonly known as saltcedar. This hardy, non-native species rapidly colonizes the receding shoreline, siphoning up to 200 gallons of water per plant daily and outcompeting native vegetation. Utilizing high-resolution satellite imagery from 2020 and 2025, this research found that saltcedar coverage within a 5 km radius of the lake increased by approximately 76.7%.

Analysis of the spatial data indicates that while the total area of infestation has exploded, the average distance of …

Hands-On Learning And Design Thinking In Secondary Design And Technology Education, Carol K. Puddicombe

Research outputs 2022 to 2026

Design and Technology (D&T) education occupies a distinctive position within the secondary curriculum through its historical emphasis on designing, making, and evaluating tangible artefacts. Drawing on a doctoral study, this article examines how the secondary school experiences of ten pre-service D&T teachers in Western Australia shaped their engagement with the subject. Using Interpretative Phenomenological Analysis, data were generated through in-depth interviews. Analysis revealed three interrelated themes: the power of practical engagement, experiences of success in the workshop, and limitations in opportunities for explicit design thinking. Findings indicate that hands-on, workshop-based learning played an important role in fostering confidence, motivation, and …

Choice-Aya: Adapting An Evidence-Based Contraceptive Counseling Intervention For Adolescents And Young Adults Experiencing Homelessness., Mariah E. Brewe, Anna Burns, Nikolaus Schuetz, Taylor Stephens, Emma Francis, Haylie Yost, Stephani L. Stancil

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Adolescents and young adults (AYA) experiencing homelessness face an increased risk of reproductive violence, unintended pregnancy, and barriers accessing healthcare. While interventions focused on efficacy-first contraceptive counseling are successful at increasing rates of long-acting reversible contraceptive (LARC) use, little is known about how an efficacy-first approach is received by AYA experiencing homelessness given unique factors associated with their reproductive health care. We aimed to adapt the evidence-based CHOICE contraceptive counseling approach for AYA experiencing homelessness.

METHODS: Focus groups discussion with AYA experiencing homelessness were conducted to understand prior reproductive health care experiences and contraception counseling preferences, comparing efficacy first …

Subject Benchmark Statement: History Of Art, Architecture And Design, Péter Bokody, Paul Alexander Stewart, Nadira Begum, Christina Bradstreet, Derrik Ferney, Ferren Gipson, Kate Grandjouan, Alison Hamilton-Pryde, Sophie Hatchwell, Christie Johnson, Lenia Kouneni, Joseph Mcbrinn, Lynda Nead, Samuel Raybone, Jennifer Walden

School of Law, Humanities and Social Sciences

No abstract provided.

Trajectories Of Plasma And Csf Mtbr-Tau243 And Phosphorylated-Tau Species Across The Alzheimer's Disease Continuum, Lyduine E Collij, Gemma Salvadó, Kanta Horie, Nicolas R Barthélemy, Tobey J Betthauser, Olof Strandberg, Ruben Smith, Sebastian Palmqvist, Suzanne E Schindler, Rik Ossenkoppele, Shorena Janelidze, Niklas Mattsson-Carlgren, Randall J Bateman, Oskar Hansson

2020-Current year OA Pubs

To efficiently implement plasma and cerebrospinal fluid (CSF) biomarkers for staging and prognosis of Alzheimer disease (AD), we must understand their dynamics across disease progression. We analyzed participants from the Swedish BioFINDER-2 study with mass spectrometry measurements of plasma and CSF tau species, including eMTBR-tau243/MTBR-tau243 and phosphorylation occupancies (%p-tau). Disease duration was estimated using Aβ-PET and tau-PET with the SILA algorithm. Bootstrapped LOESS models showed that %p-tau217 changes earliest, increasing just before Aβ-PET positivity. Other p-tau species changed later, with smaller dynamic ranges and earlier ceiling effects. %p-tau205 and MTBR-tau243 changes aligned with tau-PET positivity onset, while MTBR-tau243-especially plasma eMTBR-tau243-tracked …

Supporting Commuter Students In Uk Higher Education: Opportunities To Enhance Policy And Practice, Rebecca Turner, Rao Namrata, Christie Pritchard, Oliver Webb, Pinn E, Asal Baharloo, Harriet Ball

Professional Services

Commuter students represent a significant, yet often overlooked, demographic within English higher education (HE). Historically, national policy and institutional practice have failed to adequately acknowledge distinct challenges they face. Using a novel participatory mapping activity, and focus group discussions with 19 commuter students, this paper identifies how commuters are excluded by dominant models of university participation. We examine students’ interactions with campus, peers and staff. Findings reveal how structural norms—such as attendance expectations, financial support, and spatial assumptions—can marginalise learners who do not follow the residential model. Participants described feeling peripheral to university life, with their legitimacy as students sometimes …

Law School News: Roger Williams University School Of Law Receives Historic $4 Million Gift From Mark Mandell To Establish Premier Trial Advocacy Center 4-9-2026, Hillary Lima, Roger Williams University School Of Law

Life of the Law School (1993- )

No abstract provided.

Finding Belonging In A Religious Dominant Society: Religion Among African Migrants In Türkiye, Garrett L. Wride, Stacey A. Shaw

FHSS Mentored Research Conference

As global migration increases each year, so does the need to understand the crossroads between inclusion, wellbeing, and religion. The experience of African migrants living in Türkiye presents itself as a unique case to study migrant wellbeing. Using quantitative and qualitative analysis, this study shows that African migrants in Türkiye belonging to the religious minority have lower scores of wellbeing and social support. Findings point to the need for policy makers and mental health practitioners to ensure migrants can access their religious communities.