Digital Commons Network^™

Burgin ‘25 Seeks Solutions For Climate Change And Global Inequality, Julia Perez

News and Events (Discontinued Series)

No abstract provided.

Lung Volume Reduction For Emphysema Using One-Way Endobronchial Valves: An Australian Cohort, Calvin Sidhu, Nicholas Wilsmore, Narinder Shargill, Kanishka Rangamuwa

Research outputs 2022 to 2026

Emphysema can be associated with gas trapping and hyperinflation, which negatively impacts on quality of life, life expectancy, and functional capacity. Lung volume reduction (LVR) surgery can reduce gas trapping and improve mortality in select patients but carries a high risk of major complications. Bronchoscopic techniques for LVR using one-way endobronchial valves (EBV) have become an established efficacious alternative to surgery. A bi-center retrospective cohort study was conducted on patients with severe emphysema who underwent endoscopic lung volume reduction (ELVR) using Pulmonx Zephyr EBVs. Symptomatic patients with gas-trapping and hyperinflation on lung function testing were selected. Target-lobe selection was based …

Revolutionising Health Care: Exploring The Latest Advances In Medical Sciences, Gehendra Mahara, Cuihong Tian, Xiaojia Xu, Wei Wang

Research outputs 2022 to 2026

Recent years have seen a revolution in the domain of medical science, with ground-breaking discoveries changing health care as we once knew it [1]. These advances have considerably improved disease diagnosis, treatment, and management, improving patient outcomes and quality of life [2–5]. . . .

Sustainable Luxury Fashion Events As Platforms For Enhancing Brand Image And Reputation For Consumers And Young Professionals Entering The Fashion Industry​, Andrew Burnstine, Karima Lanfranco​

Faculty and Staff Publications & Presentations

No abstract provided.

Reduced Racial Disparity As A Result Of Survival Improvement In Prostate Cancer, Chao Cheng

Faculty, Staff and Students Publications

Prostate cancer is a cancer type associated with a high level of racial and socioeconomic disparities as reported by many previous studies. However, the changes in these disparities in the past two decades have not been systematically studied. In this study, we investigated the Surveillance Epidemiology End Results (SEER) data for prostate cancer patients diagnosed during 2004-2018. African Americans and Asians showed significantly better and worse cancer-specific survival (CSS), respectively, compared to non-Hispanic white individuals after adjusting for confounding factors such as age and cancer stage. Importantly, the data indicated that racial disparities fluctuated and reached the highest level during …

The Co-Delivery Of Adenovirus-Based Immune Checkpoint Vaccine Elicits A Potent Anti-Tumor Effect In Renal Carcinoma, Jiawei Wang, Fei Zhu, Meng Wang, Navid Sobhani, Praveen Neeli, Gang Wang, Hailong Li, Junnian Zheng, Dafei Chai

Faculty, Staff and Students Publications

Immune-based checkpoint therapy has made significant progress in cancer treatment, but its therapeutic effect is limited. A replication-defective adenovirus (Ad) vaccine encoding tumor antigen carbonic anhydrase IX (CAIX) combined with Ad-encoding immune checkpoint PD-L1 was developed to treat renal carcinoma. Three tumor models, subcutaneous, lung metastasis and orthotopic tumor were established, and Ad vaccines were used to immunize them and evaluate the vaccine's therapeutic effect. Compared to the single Ad vaccine group, the subcutaneous tumor growth was significantly reduced in Ad-CAIX/Ad-PD-L1 combination group. Co-immunization of Ad-CAIX/Ad-PD-L1 enhanced the induction and maturation of CD11c

Framing, Emotions, Salience: The Future Of Ai As Seen By Redditors, Ayse Ocal

Dissertations - ALL

With today’s advanced technological improvements, the usage of various Artificial intelligence (AI) applications is still growing. This dissertation seeks to uncover how the future of AI is perceived by the social media users through the lens of technological frames and how these perceptions shape users’ emotions, attitudes, and the level of engagement stemming from salience of the frames. This shaping process is considered a type of social influence. The concept of technological frame is defined briefly as the interpretations, assumptions, expectations, and knowledge that people have about technology. Prior research suggests frames affect emotions and attitudes, and emotions and attitudes …

Creating A Partnership Using The Home To School Connection To Implement Relevant Instruction In The Classroom And Supporting The School To Home Connection To Create A Tier Two Intervention Tailored To Students’ Early Literacy Needs, Sara L. Arthurs

Masters Projects

A child’s first place of learning is within the home environment. Research has proven the importance of family involvement in developing children’s early literacy skills. Children have academic success when family members are involved and supportive of development. Early elementary students are expected to enter formal schooling already holding knowledge of foundational literacy skills. The home environment offers children the opportunity to learn and support later literacy success. However, there has been a disconnect between how family and schools partner which has impacted how families engage in their child’s educational experience. Schools and teachers should continue to partner with families …

Glycemic Markers And Insulin-Related Parameters In The Progression Of Diabetes And Lower Extremities Complications: A Pilot Study In Mexican Americans From Starr County, Peter Elvin, Garrett Edwards, Walid Fakhouri, Craig Hanis, Cláudia Cristina Biguetti

School of Podiatric Medicine Publications

No abstract provided.

The Importance Of Security Leadership Involvement In Crisis Response Practice For Real-Life Emergencies, Alan Saquella

Publications

In today’s dynamic business and socioeconomic landscape, the potential for crises to disrupt entity operations and tarnish reputations is an ever-present reality. From natural disasters and cyber-attacks to financial meltdowns and product recalls, organizations must be unwaveringly prepared to navigate worst-case scenarios effectively. Crisis management and crisis communication experts unequivocally stress the critical importance of practicing responses to such crises, and the involvement of security leadership plays a crucial role in ensuring comprehensive preparedness. In this article, we delve into the undeniable advantages of preparing for real-life emergencies through rigorous simulation and training with the active engagement of security leadership.

Shp2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors To Re-Treatment With Targeted Therapy, Shirish Gadgeel, Micaela B Reddy, Allison S Harney, Mohamed Elsayed, Adam W Cook, Christina E Wong, Ronald J Hinklin, Yutong Jiang, Eric N Brown, Nickolas A Neitzel, Ellen R Laird, Wen-I Wu, Anurag Singh, Ping Wei, Keith A Ching, John J Gaudino, Patrice A Lee, Dylan P Hartley

Faculty, Staff and Student Publications

Rationally targeted therapies have transformed cancer treatment, but many patients develop resistance through bypass signaling pathway activation. PF-07284892 (ARRY-558) is an allosteric SHP2 inhibitor designed to overcome bypass-signaling-mediated resistance when combined with inhibitors of various oncogenic drivers. Activity in this setting was confirmed in diverse tumor models. Patients with ALK fusion–positive lung cancer, BRAF^V600E-mutant colorectal cancer, KRAS^G12D-mutant ovarian cancer, and ROS1 fusion–positive pancreatic cancer who previously developed targeted therapy resistance were treated with PF-07284892 on the first dose level of a first-in-human clinical trial. After progression on PF-07284892 monotherapy, a novel study design allowed the addition …

Human Ecology News, Georgia Southern University

Human Ecology: News & Publications (2012-2023)

• Rachel Peden, FMAD, wins scholarship

Assessing The Effectiveness Of Open Innovation Implementation Strategies In The Promotion Of Ambidextrous Innovation In Thai Small And Medium-Sized Enterprises, Wutthiya A. Srisathan, Chavis Ketkaew, Phaninee Naruetharadhol

Publications

The adoption of open innovation practices is becoming increasingly important for SMEs seeking to remain competitive in today's fast-paced business environment. The aim of this study is to understand the implementation of open innovation processes by SMEs while highlighting two critical processes: open innovation implementation (OII) and open ambidextrous innovation practices (OAIP). The study employes a second-order factor analysis incorporating multigroup structural invariance analysis to explore the differences in ambidextrous innovation practices across SME size categories using a sample of 615 SMEs in Thailand. The primary finding reveals and confirms a statistically significant positive relationship between the implementation of open …

Developing A New Three-Dimensional Finite-Difference Explicit In Time Solver Package For Modflow, Babak Azari

Electronic Theses and Dissertations Archive

Integrating existing surface water (SW) and groundwater (GW) models like SWAT, MODFLOW, and HEC-RAS has been explored to simulate the complexities of SW-GW interactions. Still, challenges arise from temporal and spatial scale disparities. To tackle the temporal scale issue, this study introduces the novel explicit solver (EXP1) for MODFLOW 2005, enabling daily GW modeling similar to SWAT and HEC-RAS by reducing runtime and computational burden. The proposed solver incorporates a stability criterion to assess the stability of the proposed solver. The study compared the EXP1 solver to the widely used Preconditioned Conjugate Gradient (PCG) solver in three scenarios: a 1D …

Disordered Eating Behaviors In Nonbinary Populations: Exploring The Unique Roles Of Body Dissatisfaction, Gender Dysphoria, And Misgendering, Raven Callahan Cohen

Electronic Theses and Dissertations Archive

Nonbinary individuals have long been underrepresented in eating disorder research despite gender minority risk factors that place them at higher risk for gender-based discrimination, which impacts mental health outcomes including eating disorder pathology. Nonbinary individuals often present themselves in such a way that rejects body image ideals that may also lead to body dissatisfaction and gender dysphoria in relation to gendered expectations, which is a known risk factor of disordered eating. The current study investigated how body dissatisfaction, gender dysphoria, and misgendering predicted disordered eating behaviors in a sample of 130 nonbinary participants. Unexpectedly, body dissatisfaction was significantly and inversely …

An Evaluation Of A Perinatal Bereavement Treatment Program For Infant Loss: Risk Factors, Treatment, And Healing, Mary Hilgeman Neal

Electronic Theses and Dissertations Archive

Abstract One in five mothers experience a perinatal mood or anxiety disorder (PMAD), and parents who have suffered infant loss are more at risk of experiencing mental health symptoms than other new parents. There are numerous risk factors for perinatal women developing a mood or anxiety disorder, including a history of depression, lack of support, and negative childhood experiences. This study followed more than 1,000 mothers who participated in an integrated behavioral health perinatal bereavement family support program in the Southeast region of the United States from 2015–2023. Mothers who have suffered from infant loss were found to have a …

Exploring The Ways Black Choral Conductors Negotiate Racism And Nonculturally Relevant Leadership In Choral Music Spaces In The United States, Cordara Harper

Electronic Theses and Dissertations Archive

The purpose of this narrative inquiry was to understand the ways Black choral conductors negotiated racism and nonculturally-relevant choral music leadership in the United States. I sought to address the following research questions: (a) How do Black choral conductors experience racism in choral settings?; (b) How do Black choral conductors describe an ideal culturally relevant–led choral music setting?; and (c) How have their experiences influenced or informed their decisions as choral conductors today? Using critical race theory (CRT) and culturally relevant leadership learning model (CRLL) as the macro-level theoretical lenses and narrative inquiry as the methodology, I sought counternarratives to …

Reply Brief Of The Petitioners-Taxpayers Edward A. And Doris Zelinsky, Edward A. Zelinsky

Amicus Briefs

The Division’s Brief confirms that the Tribunal should rule for the taxpayers, Edward A. and Doris Zelinsky Perhaps most egregiously, the Division disparages binding factual stipulations to which the parties agreed at the outset of this litigation. These stipulations confirm that, from March 15, 2020 through December 31, 2020 (“the COVID period”), Professor Zelinsky had no New York office or classroom available to him. Consequently, Professor Zelinsky taught his classes and met with students exclusively on zoom from his Connecticut home. He did not step foot in New York for this nine and one-half month period.

The stipulated facts lead …

Discovery Of Gamma Rays From The Quiescent Sun With Hawc, A. Albert, R. Alfaro, C. Alvarez, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, R. Babu, E. Belmont-Moreno, C. Brisbois, K. S. Caballero-Mora, T. Capistrán, A. Carramiñana, S. Casanova, O. Chaparro-Amaro, U. Cotti, J. Cotzomi, S. Coutiño De León, E. De La Fuente, R. Diaz Hernandez, B. L. Dingus, M. A. Duvernois, M. Durocher, J. C. Diaz-Velez, R. W. Ellsworth, K. Engel, C. Espinoza, K. L. Fan, K. Fang, M. Fernandez Alonso, H. Fleischhack, N. Fraija, J. A. Garcia-Gonzalez, F. Garfias, M. M. Gonzalez, J. A. Goodman, J. P. Harding, S. Hernandez, J. Hinton, D. Huang, F. Hueyotl-Zahuantitla, P. Huntemeyer, A. Iriarte, V. Joshi, S. Kaufmann, J. Lee, J. T. Linnemann, A. L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, J. Martinez-Castro, J. A. Matthews, P. Miranda-Romagnoli, J. A. Morales-Soto, E. Moreno, M. Mostafa, A. Nayerhoda, L. Nellen, M. U. Nisa, R. Noriega-Papaqui, L. Olivera-Nieto, N. Omodei, Y. Perez Araujo, E. G. Perez-Perez, C. D. Rho, D. Rosa-Gonzalez, E. Ruiz-Velasco, H. Salazar, D. Salazar-Galeggos, A. Sandoval, M. Schneider, J. Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Urena-Mena, E. Varela, J. Villasenor, Xiaojie Wang, I. J. Watson, E. Willox, S. Yun-Carcamo, H. Zhou, C. De Leon

Physics Faculty Research & Creative Works

We report the first detection of a TeV γ-ray flux from the solar disk (6.3σ), based on 6.1 years of data from the High-Altitude Water Cherenkov (HAWC) observatory. The 0.5-2.6 TeV spectrum is well fit by a power law, dN/dE=A(E/1 TeV)-γ, with A=(1.6±0.3)x10-12 TeV-1 cm-2 s-1 and γ=3.62±0.14. The flux shows a strong indication of anticorrelation with solar activity. These results extend the bright, hard GeV emission from the disk observed with Fermi-LAT, seemingly due to hadronic Galactic cosmic rays showering on nuclei in the solar atmosphere. However, current theoretical models are unable to explain the details of how solar …

Training Certified Detectives To Track Down The Intrinsic Shortcuts In Covid-19 Chest X-Ray Data Sets, Ran Zhang, Dalton Griner, John W. Garrett, Zhihua Qi, Guang-Hong Chen

Diagnostic Radiology Articles

Deep learning faces a significant challenge wherein the trained models often underperform when used with external test data sets. This issue has been attributed to spurious correlations between irrelevant features in the input data and corresponding labels. This study uses the classification of COVID-19 from chest x-ray radiographs as an example to demonstrate that the image contrast and sharpness, which are characteristics of a chest radiograph dependent on data acquisition systems and imaging parameters, can be intrinsic shortcuts that impair the model's generalizability. The study proposes training certified shortcut detective models that meet a set of qualification criteria which can …

Conserved Temporal Processing Principles In Olfactory Systems, Doris Ling

McKelvey School of Engineering Graduate Student Theses & Dissertations

Olfaction is a primitive sensory modality used by animals to perform basic functions such as searching for food or mates. Olfactory cues are highly temporally dynamic and therefore time is an important encoding dimension in this sensory modality. How olfactory information is encoded by the temporal patterns of neural responses remains a fundamental question in the field of sensory neuroscience. Furthermore, it is not understood whether different organisms employ similar neural encoding principles. In this work, I investigated how neural activity is patterned over time in the primary olfactory system of the American bird locust (Schisctocerca americana). Previous studies have …

Translating Deep Learning Into Scientific Domains: Case Studies In Bioactivation, Quantum Chemistry, And Clinical Studies, Kathryn Sarullo

McKelvey School of Engineering Graduate Student Theses & Dissertations

Artificial intelligence has made substantial progress in resolving key issues in a variety of scientific and technical domains, particularly in cross-disciplinary sciences. Deep learning is becoming ubiquitous, particularly in biology, healthcare, and drug discovery. Deep learning techniques offer chances to advance science with the potential to significantly outperform state-of-the-art approaches in many scientific fields. There are, however, notable challenges. Each discipline in which deep learning could be applied has a unique manner of communicating concepts, which we describe as interpretability, critical for use in science, both in industry and academia. Interpretability can be defined as decisions made during visualization generation …

Neighborhood- And Finer-Scale Spatial Variations In Environmental Noise And Air Pollution, Maryssa Loehr

McKelvey School of Engineering Graduate Student Theses & Dissertations

The urban environment contains both air pollution and noise pollution from various sources. For noise pollution, sources include biogenic emissions such as insect chorus and anthropogenic emissions such as highway traffic and airplane flyovers. Numerous studies link exposure to noise with increased health risks through mechanisms such as disruption of sleep and introduction of external stress factors. It is not clear whether biogenic and anthropogenic noise have differential impacts. Ultrafine particulate matter (UFP) contribute to adverse health outcomes such as asthma, obstructive pulmonary disease, cardiovascular disease, and lung cancer. Ambient UFP is currently not regulated in the United States with …

2022 Final Unreclaimed Sites Quality Assurance Project Plan (Qapp) Revision 1, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

2022 Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp) Revision 2, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Developing Strategies For The Integration Of Metal–Organic Frameworks (Mofs) Into E-Textiles For Chemical Sensing, Filtration, And Detoxification, Aileen Mary Eagleton

Dartmouth College Ph.D Dissertations

Metal-organic frameworks (MOFs) are crystalline porous materials that offer modularity through diverse combinations of metal nodes and linkers, as well as tailorable surface chemistry and structure, along with tunable conductivity. The integration of these framework materials onto fibers can result in robust and flexible MOF-based textiles with enhanced functionality and applicability. This thesis illustrates the versatility of multifunctional MOF-integrated textile systems, showcasing their unique properties and the advantages of installing MOFs at the fiber level.

Catalog Of The World Species Of Trichodesma Leconte, 1861 (Coleoptera: Ptinidae) And Associated Genera, Kyle E. Schnepp

Insecta Mundi

A catalog of the species of Trichodesma LeConte (Coleoptera: Ptinidae) for the world is provided, including synonyms and misspellings. Six additional genera, Anobiopsis Fall, Belemia Español, Nanodesma Zahradník, Nicobium LeConte, Trichobiopsis White, and Trichodesmina Español, are also cataloged for com­pleteness. The species name, author, year, and page number of description are given for each species, as well as references for combinations by different authors. The type depository is given when known, and followed by a “?” when unknown but suspected, and a general distribution is given by region of the world followed by country. Authorship of the genus Trichodesma in …

Biology Of The Sineguelas Leaf Beetle, Podontia Quatuordecimpunctata (L.) (Chrysomelidae: Galerucinae: Alticini), On Spondias Purpurea L. (Anacardiaceae) In The Philippines, Orlando A. Calcetas, Charles L. Staines, Caroline Simmrita Chaboo, Rachel Ann A. Anabo, Monalisa O. Recuenco

Insecta Mundi

Spondias purpurea L. (Anacardiaceae), native to the Neotropical region, is cultivated in the Phil­ippines for the edible fruits and the tree is economically significant. The adventive leaf beetle, Podontia quatuordecimpunctata (L.) (Chrysomelidae: Galerucinae: Alticini), has become a major defoliating pest of the tree in the country. The Philippines government has initiated study of the pest, now locally called the sineguelas leaf beetle (SLB). This paper reports the results of a one-year field study on the biology of SLB on S. purpurea (red sineguelas), in Batangas City, Philippines. The SLB eggs hatch in 5–7 days. The larval period is 14–16 …

Potential Of Mirnas In Plasma Extracellular Vesicle For The Stratification Of Prostate Cancer In A South African Population, Dada Oluwaseyi Temilola, Martha Wium, Juliano Paccez, Azola Samkele Salukazana, Hasan H. Otu, Giuseppina M. Carbone, Lisa Kaestner, Stefano Cacciatore, Luiz Fernando Zerbini

Department of Electrical and Computer Engineering: Faculty Publications

Prostate cancer (PCa) is the most common cause of cancer death among African men. The analysis of microRNAs (miRNAs) in plasma extracellular vesicles (EVs) can be utilized as a non-invasive tool for the diagnosis of PCa. In this study, we used small RNA sequencing to profile miRNAs cargo in plasma EVs from South African PCa patients. We evaluated the differential expression of miRNAs between low and high Gleason scores in the plasma EVs of South African patients and in the prostatic tissue from data available in the Cancer Genome Atlas (TCGA) Data Portal. We identified 7 miRNAs differently expressed in …

Comparison Of Library Publishing Workflows By Oa Model, Sue Ann Gardner

University of Nebraska-Lincoln Libraries: Presentations

Population of an institutional repository is a form of publishing. Green and diamond OA library publishing workflows are compared. The workflow for gold OA does not involve library publishing. Some data about the UNL Digital Commons institutional repository (https://digitalcommons.unl.edu) are included.