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Articles 45571 - 45600 of 5202349
Full-Text Articles in Entire DC Network
Drowned, Pleasured And Veiled, Taylor Simone Gearhart
Drowned, Pleasured And Veiled, Taylor Simone Gearhart
Theses - ALL
Drowned, Pleasured and Veiled explores how societal ideas around romantic passion can mask manipulative and violent behavior. It examines historical and pop cultural representations of romance that give cover to the everyday violence that patriarchy visits on women within intimate relationships. This body of work explores themes of shame, control, desire, and the ways physical and emotional violence can be threaded throughout those experiences. Through photography and performance, the artist visualizes and interrogates the ways power pervades intimate relationships.
Who Gets Better Buses? Studentification, Bus Geographies, And Transit Privilege In Postindustrial Upstate New York, Carlos Jose Gonzalez
Who Gets Better Buses? Studentification, Bus Geographies, And Transit Privilege In Postindustrial Upstate New York, Carlos Jose Gonzalez
Theses - ALL
Decades of deindustrialization have forced several American cities to seek other sources of economic life for their shrinking populations and increasingly impoverished populations. One sector that has shown much potential for revitalization has been the “meds and eds” of hospitals and universities. The growth of higher education is fueled by a rise in enrollment that has transformed the demographic, economic, and social atmospheres of university neighborhoods. Yet an important transformation missed by these “studentification” scholars are the accompanying reconfigurations of public transit. Given that students, and young people generally, are less likely to own their own car, universities have to …
Authentic And Thriving: The Role Of Authenticity In Friendship And Well-Being, Arina Stoianova
Authentic And Thriving: The Role Of Authenticity In Friendship And Well-Being, Arina Stoianova
Theses - ALL
Generally, authentic people have satisfying close relationships and greater well-being (Rivera et al., 2019). Having satisfying friendships is important for personal well-being and a fulfilling life (Anderson & Fowers, 2020). Thus, in three pre-registered studies, I tested whether authenticity is related to well-being through friendship satisfaction among single and partnered people. In Study 1 (N=326), singles’ authenticity was associated with having satisfying friendships, which in turn predicted greater general well-being (i.e., life satisfaction and purpose in life), but not singlehood-specific outcomes. In Study 2 (N = 623), I examined whether this finding extends to partnered people’s well-being and found that …
Sexual Identity And Sleep Health In Adolescents: The Role Of Parenting Practices, Alexa Grace Deyo
Sexual Identity And Sleep Health In Adolescents: The Role Of Parenting Practices, Alexa Grace Deyo
Theses - ALL
Adolescence is a developmental period marked by heightened vulnerability to insufficient sleep, which contributes to adverse emotional, cognitive, and physical health outcomes. Evidence indicates that adolescents who identify as lesbian, gay, and bisexual (LGB) are at an increased risk for poor sleep relative to their heterosexual peers. However, little is known about which dimensions of sleep health differ by sexual identity or modifiable factors that may underlie these differences. This study examined whether adolescent sleep duration, sleep efficiency, and daytime sleepiness differed by sexual identity, and investigated whether parental acceptance and parental monitoring helped explain these differences. Participants were 5,919 …
Data-Driven Approaches To Investigate Cardiotoxicity Using Hipscs High Throughput Screening, Danny Vu
Data-Driven Approaches To Investigate Cardiotoxicity Using Hipscs High Throughput Screening, Danny Vu
Theses - ALL
Recent advances in human induced pluripotent stem cell (hiPSC) technology have enabled the development of high-throughput platforms for cardiotoxicity screening. However, conventional analytical approaches remain limited by time-intensive processing, manual annotation requirements, and reduced scalability for large datasets. To address these challenges, calcium fluorescence signals from human induced pluripotent stem cell-derived cardiomyocytes (hiPSC CMs) were analyzed using a high-throughput imaging platform and complementary machine learning frameworks. First, a feature-based supervised learning approach using engineered waveform descriptors and low-dimensional signal embeddings enabled rapid and interpretable screening of large chemical datasets, with combined features improving predictive performance relative to engineered features alone. …
Persuasive Effects Of Paired Synthetic Images In Online Branding: A Comparative Study Using Elaboration Likelihood Model, Cancan Yu
Theses - ALL
The growing use of artificial intelligence (AI) in brand visuals has prompted interest in whether presenting synthetic images alongside real counterparts changes how consumers engage with and evaluate them. This between-subjects online experiment (N = 211) tested whether paired versus single presentation of synthetic and real brand images affected engagement and attitudes, including perceived trustworthiness and perceived attractiveness, using the Elaboration Likelihood Model (ELM). Results did not reveal that presentation format affects engagement, engagement predicts either attitudinal outcome, or format moderates the engagement-attitude relationship. The strong covariance between trustworthiness and attractiveness may reflect a holistic mode of brand evaluation or …
Blue-Collar Belonging: How An Analysis Of Identity, Epistemics, And Stance Reveal Fluid Community Membership In Rural Upstate New York, Kennedy Reed Jones
Blue-Collar Belonging: How An Analysis Of Identity, Epistemics, And Stance Reveal Fluid Community Membership In Rural Upstate New York, Kennedy Reed Jones
Theses - ALL
This thesis examines how community membership is constructed in everyday conversations amongst rural blue-collar people in Upstate New York. Through a sociolinguistic approach, the data from this project was collected by recording naturally occurring conversations of rural blue-collar community over a year. These conversations were then transcribed and coded, seeking out pockets of blue-collar topics in the conversations. When doing this, blue-collar/blue-collar experiences were understood as manual work, typically not done in an office, and that does not often require a degree. Therefore, by drawing on sociolinguistic scholarship on identity, epistemics, and stance, this project argues that membership in this …
Assessing The Impact Of Land Use Land Cover Change On Habitat Quality In Onondaga County, New York: A Thirty-Year Spatial Analysis., Favour Nkwando Sedwaa
Assessing The Impact Of Land Use Land Cover Change On Habitat Quality In Onondaga County, New York: A Thirty-Year Spatial Analysis., Favour Nkwando Sedwaa
Theses - ALL
The Earth's terrestrial surface is experiencing rapid and unprecedented transformation driven by human land use activities. An estimated 75% of the global land area has been altered, and land-use and land-cover change (LULCC) is widely recognized as the largest contributor to biodiversity loss worldwide. Habitats, the ecological spaces that sustain biodiversity, are particularly vulnerable to the compounding pressures of habitat loss and fragmentation associated with urbanization and agricultural intensification. This study investigates the impacts of LULCC on landscape fragmentation and habitat quality in Onondaga County, New York, over a 30-year period from 1994 to 2024. Using Annual National Land Cover …
Beyond The Policy - Designing A Healing Campus For Xinhua's Children, Katharine Massey
Beyond The Policy - Designing A Healing Campus For Xinhua's Children, Katharine Massey
Bachelor of Architecture Theses - 5th Year
To some people children are seen as a blessing, but for China, they were considered detrimental to the economy status of the country. For 35 years China implemented a policy that limited families to one child so they could curb their rapid population growth and keep their image of being an economic leader of the world. This thesis will look at the lasting impact the one-child policy had on the population of China and the results that have emerged since the law has ended, along with the 2024 stop on foreign adoption programs and who was most impacted by it. …
Women In Literature And Their Ephemeral Bodies, Madeline Zafon-Whalen
Women In Literature And Their Ephemeral Bodies, Madeline Zafon-Whalen
English Honors Theses
This thesis is a comparative analysis of women writers from the twentieth to twenty-first century. Works by authors such as Virginia Woolf, Margaret Atwood, and Otessa Moshfegh, contain an emerging pattern and relationship linked through an ephemeral bodied aesthetic which depicts women's bodies as deconstructed, intangible, and undefined.
The first chapter analyzes works by Woolf, including To the Lighthouse and A Room of One's Own. Starting in the modernist age we see the body coming into question, becoming denaturalized while the institution of the "novel" is renewed through women's contributions to the literary canon. Women’s productivity, and the potential to …
Poem--Henry Wadsworth Longfellow, "Kéramos" (1844)
Poem--Henry Wadsworth Longfellow, "Kéramos" (1844)
The International Journal of Ecopsychology (IJE)
No abstract provided.
The Impact Of Stress On Selective Attention Among College Student Athletes, Jayla K. Mcgaffin
The Impact Of Stress On Selective Attention Among College Student Athletes, Jayla K. Mcgaffin
Honors Theses
Student athletes face unique stressors from balancing academic and athletic demands (Lopes Dos Santos et al., 2020), which may deplete cognitive resources and impair focus. The present study examined the relationship between perceived stress and selective attention among college student athletes. Stress was conceptualized as the interaction between external pressures and individual coping responses (Lazarus & Folkman, 1984). Twenty undergraduate student athletes from the University of New Haven completed the Perceived Stress Scale (PSS-14) and a computerized Flanker task measuring selective attention, but only eighteen were used in the final correlation analysis. It was hypothesized that higher levels of perceived …
Cell Cycle Inhibition: Illudin S And Its Effects On Cdk2 In Ewing Sarcoma, Stephanie Diez, Natalie Flores, Alexandria Hernandez, Viviana Palacios, Terry Jo Shackleford
Cell Cycle Inhibition: Illudin S And Its Effects On Cdk2 In Ewing Sarcoma, Stephanie Diez, Natalie Flores, Alexandria Hernandez, Viviana Palacios, Terry Jo Shackleford
Cell and Molecular Methods
Ewing Sarcomas are aggressive round cell mesenchymal neoplasmas that have a high occurrence in children and young adults. CDK2 is a protein that is involved in the G1 phase of the cell cycle, which promotes the transition to the S phase. CDK2 kinase activation is mainly observed in the G1/S-phase transition.3 CDK2 binds to Cyclin proteins is responsible for entry and progression, thereby leading to maximal apoptosis activity in the S-phase. Illudin S is a drug that has been known to target cancer-specific cells, such as leukemia. Illudin S, in general are a cytotoxic metabolite that comes from plants, specifically …
Yap1 Knockdown And Panobinostat Treatment Increase Apoptotic Response And Decrease Gene Expression In Ewing Sarcoma Cells, Luna Collazo-Garcia, Alejandra Favela Santos, Madeline Torres-Salazar, Isabella Toscano, Terry Jo Shackleford
Yap1 Knockdown And Panobinostat Treatment Increase Apoptotic Response And Decrease Gene Expression In Ewing Sarcoma Cells, Luna Collazo-Garcia, Alejandra Favela Santos, Madeline Torres-Salazar, Isabella Toscano, Terry Jo Shackleford
Cell and Molecular Methods
Ewing sarcoma (EWS) is considered to be one of the most aggressive pediatric malignancies, often characterized by its dysregulated gene expression driven by oncogenic fusion proteins. The Hippo signaling effector Yes-associated protein 1 (YAP1) has been known in promoting cell proliferation, survival, and therapeutic resistance in multiple cancers. However, its role in Ewing sarcoma response to treatment remains unclear. This study investigated whether YAP1 knockdown enhances the sensitivity of Ewing sarcoma cells to the histone deacetylase inhibitor Panobinostat. Ewing sarcoma, ES8, cells were transfected with a YAP1-targeting siRNA (siYAP1) or a non-targeting control (siControl) and treated with DMSO, 0.1 μM, …
Everolimus Treatment Combined With Akt1 Knockdown Increased Apoptosis And Decreased Cell Proliferation In Ewing Sarcoma Cells, Arisha Arif, Alfie Barcenez, Sophia Ruter, Nicole Vanegas-Riddick, Terry Jo Shackleford
Everolimus Treatment Combined With Akt1 Knockdown Increased Apoptosis And Decreased Cell Proliferation In Ewing Sarcoma Cells, Arisha Arif, Alfie Barcenez, Sophia Ruter, Nicole Vanegas-Riddick, Terry Jo Shackleford
Cell and Molecular Methods
The purpose of this study is to use the gene AKT1, due to the interest in AKT1’s role in cancer cell proliferation, and the drug Everolimus, to determine if combined targeted therapy works as a more efficient therapeutic approach. Ewing Sarcoma has been connected to chromosomal translocations and is most common in pediatric patients. It is most often treated with chemotherapy and local treatments. It may be connected to the gene AKT1 due to how it regulates cell metabolism, growth, and proliferation. The gene mTOR is similarly connected to cell metabolism and proliferation, and is inhibited by the drug Everolimus. …
Sirna Knockdown Of Rptor Reduces Rptor Expression, Increases Brd4 Expression, And Alters Proliferation And Apoptosis In Ewing's Sarcoma Cells, Sergio Cipriano, David Leavitt, Michael Olivia, Liam Valdez, Terry Jo Shackleford
Sirna Knockdown Of Rptor Reduces Rptor Expression, Increases Brd4 Expression, And Alters Proliferation And Apoptosis In Ewing's Sarcoma Cells, Sergio Cipriano, David Leavitt, Michael Olivia, Liam Valdez, Terry Jo Shackleford
Cell and Molecular Methods
Ewing sarcoma is a highly aggressive cancer that primarily affects children and young adults. Although treatment options exist, many patients do not respond effectively, showing the need for improved targeted therapies. RPTOR is a key in mTORC1 complex which regulates cell growth, proliferation, and survival. LY2874455 is a selective pan-FGFR inhibitor that targets growth factor signaling pathways involved in tumor progression, and FGFR signaling interacts with pathways such as mTOR, making it a potential target for combination therapies. We hypothesized that silencing RPTOR in Ewing sarcoma cells would disrupt mTOR signaling and alter expression of genes linked to cell survival …
Everolimus And Sirna-Mediated Mtor Inhibition Reduces Proliferation And Promotes Apoptosis In Ewing Sarcoma Cells, Dylan Calvert, Malorie Martinez, Alexa Miner, Ellis Quiroga, Terry Jo Shackleford
Everolimus And Sirna-Mediated Mtor Inhibition Reduces Proliferation And Promotes Apoptosis In Ewing Sarcoma Cells, Dylan Calvert, Malorie Martinez, Alexa Miner, Ellis Quiroga, Terry Jo Shackleford
Cell and Molecular Methods
Ewing Sarcoma (ES) is an aggressive pediatric bone cancer characterized by rapid cell proliferation and poor prognosis, making the identification of therapeutic targets critical. One of the mechanistic targets is rapamycin (mTOR) signaling pathway, which is critical for regulating cell growth, proliferation, and survival. Abnormal activation of the mTOR signaling pathway has been linked to the progression of ES, as it drives uncontrolled cell growth and apoptosis resistance. Because mTOR represents a promising therapeutic target for ES treatment, we hypothesized that inhibiting mTOR activity through an siRNA-mediated knockdown or through Everolimus drug treatment, would reduce cell proliferation and promote ES …
Addressing Childhood Obesity In Low-Income Communities In Massachusetts, Alexa Thomas
Addressing Childhood Obesity In Low-Income Communities In Massachusetts, Alexa Thomas
Capstones
No abstract provided.
A Dynamic Assessment Of Writing Apprehension In Elementary And Middle School Students Undergoing A Writing Intervention, Jennifer Lin Williams
A Dynamic Assessment Of Writing Apprehension In Elementary And Middle School Students Undergoing A Writing Intervention, Jennifer Lin Williams
Theses - ALL
Writing apprehension refers to fear or anxiety associated with writing tasks, avoidance of writing, and concern over evaluation of written works (Daly & Miller, 1975c). Although extensively studied in college-aged populations, where elevated apprehension is linked to reduced text production (Limpo, 2018) and diminished sentence complexity and quality (Faigley et al., 1981), research in elementary students remains limited. Existing studies have relied on adaptations of the Writing Apprehension Test (Daly & Miller, 1975c), originally validated for adults, and have typically employed cross-sectional designs, leaving the developmental trajectory of writing apprehension underexplored. To address these gaps, the present study examined changes …
Affective Labor And Deservingness In Global Care Economies: A Comparative Film Analysis In Brazilian And U.S. Cinema, Débora Ferreira Leite
Affective Labor And Deservingness In Global Care Economies: A Comparative Film Analysis In Brazilian And U.S. Cinema, Débora Ferreira Leite
Theses - ALL
This thesis examines how contemporary cinema constructs narratives of migration, care labor, and social mobility through representations of Latina caregivers. Focusing on two films, Knives Out (2019), directed by Rian Johnson, and Diários de Intercâmbio (The Secret Diary of an Exchange Student, 2021), directed by Bruno Garotti, the project explores how cinematic narratives shape cultural understandings of care work, migration, and the American Dream. Although these films emerge from different national industries and genres, both center Latina women navigating transnational labor arrangements and aspirations for social mobility in the United States. Drawing on scholarship on the global care economy, transnational …
Talking To The Eyes: Paradoxes Of Ineffability And Effusivity In Mark-Making, Theodore Xavier Berg
Talking To The Eyes: Paradoxes Of Ineffability And Effusivity In Mark-Making, Theodore Xavier Berg
Theses - ALL
Redefining mark-making as an active form of material signification has helped me understand my experience of the paradox of ineffability. This experience is as accurately described by the term effusivity as it is by ineffability, because it is not a matter of what cannot be expressed, but rather of what cannot not be expressed; of the experience that inescapably accompanies expression and signification. As our material means of expression and signification evolve digitally, the consequences of their contradictions become more discernible.
The Trouble With Being Human, Sam Bray
The Trouble With Being Human, Sam Bray
Theses - ALL
Grief, Trauma and the Invisible Spaces We Cannot Leave
Effects Of Combined Action Observation, Motor Imagery, And Neuromuscular Electrical Stimulation On Muscle Strength And Size During Short-Term Upper Limb Immobilization, Zahra Pourhatami
Theses - ALL
Short-term limb immobilization induces rapid declines in muscle strength that exceed reductions in muscle size, suggesting a dominant role of neural mechanisms in early functional decline. Interventions capable of simultaneously targeting central neural and peripheral muscular pathways may therefore offer superior protection during disuse, yet such combined approaches remain unexamined in upper limb immobilization models. To investigate the effects of combined action observation with motor imagery (AOMI) and neuromuscular electrical stimulation (NMES) (AOSTIM) on muscle strength, size, and quality during 7 days of upper limb immobilization, we conducted a study in healthy young adults. Forty-three healthy young adults were randomly …
Polymer Concentration Driven Tuning Of Drug Release In Nano-In-Microparticle Systems For Immunomodulation, Jason Bae
Theses - ALL
Osteoarthritis (OA), a disease caused by the wearing and tearing of articular cartilage, affects over 32.5 million Americans. Synovial inflammation is now recognized as a major contributor to OA progression and pain. Activated synovial macrophages in an OA joint are believed to play a major role in low-grade inflammation found in OA. Bisphosphonates such as zoledronic acid (ZA) are known to induce apoptosis specifically in macrophages and several of them are being evaluated as a disease-modifying osteoarthritis drug in clinical trials. Zolendroic Acid (Zol) is a biphosphonate that is most commonly used for treatments in bone-related diseases. Previous research reported …
Going Live: How Twitch Appearances Shape Voter Perceptions Of Political Candidates, Leah H. Ross
Going Live: How Twitch Appearances Shape Voter Perceptions Of Political Candidates, Leah H. Ross
Theses - ALL
This paper examines the persuasive power of political candidates appearing on livestreaming platforms as a campaign strategy for targeting younger, politically disengaged voters. Drawing on the theoretical frameworks of platform affordances, parasocial interaction, celebrity endorsement, and source credibility, it argues that the unique digital architecture of livestreaming sites creates media conditions distinct from traditional broadcast media and other social media. These conditions amplify parasocial experiences, telepresence, and flow, making audiences potentially more receptive to political messaging. The paper then situates livestream appearances within the broader tradition of celebrity endorsements and the growing influence of social media in campaign communication. It …
Complementation In Guadeloupean Creole: An Experimental And Computational Account, William Joseph Kezerian
Complementation In Guadeloupean Creole: An Experimental And Computational Account, William Joseph Kezerian
Theses - ALL
This thesis presents an experimental and computational investigation of complementizer variation in Guadeloupean Creole (GC). Despite its morphosyntactic innovations distinct from its lexifier, French, the subordinate structure of GC remains understudied. The project presented here involves a psycholinguistic experiment targeting complementizer usage, using binary choice tasks to gather grammaticality judgments. This was administered during field research in Guadeloupe to 9 youth speakers and 11 adult speakers of GC and French. Ethnographic interview recordings in GC were also collected from adult speakers, which were then transcribed for the purpose of text extraction of key words. I use NLP text-mining methods such …
Simulated Intelligence, Surveillance, And Play, Atienah Cape
Simulated Intelligence, Surveillance, And Play, Atienah Cape
Theses - ALL
This MFA thesis explores modern panopticism and the feeling of being watched by creating and installing Four Real Friends, an interactive robotic artwork inspired by the 1998 Furby. The project looks at how surveillance technologies are not just outside forces, but part of daily life, often feeling familiar, playful, and even social. The installation uses hardware design, custom circuits, computer vision, and real-time data display to collect and process how visitors interact in the gallery. Its nostalgic and friendly look encourages people to take part, while still showing how data is collected and displayed as it happens. This makes surveillance …
Kitchen As An Archive: Konkani Food, Memory, And Identity In India, Sanjana Sharma
Kitchen As An Archive: Konkani Food, Memory, And Identity In India, Sanjana Sharma
Theses - ALL
The Konkani community has often struggled to find an effective way to preserve its culture. Colonial conflict, regional division, and diasporic migration have stood in the way of creating a unified identity. My thesis argues that Konkani cooking traditions comprising heirloom ingredients, conventional cooking tools, ceremonial food practices, and adaptable diaspora recipes constitute a vibrant and evolving repository. This makes the kitchen an essential yet overlooked space for cultural memory. Concentrating specifically on the Konkani communities in Karnataka, I explore how ingredients such as Kokum underscore an understanding of plant ecologies; how seafood sheds light on coastal traditions; how gendered …
Assessing Knowledge And Decision-Making In Basic Genomics Among Adolescents And Adults, Sidharth Masarur
Assessing Knowledge And Decision-Making In Basic Genomics Among Adolescents And Adults, Sidharth Masarur
Honors Scholar Theses
Background
Genetic testing and genomic sequencing are increasingly part of pediatric care, yet many adolescents and parents lack the knowledge needed to make informed decisions. Prior studies show gaps in understanding, even among highly educated families, raising concerns about the adequacy of consent and assent. Little is known about when youth begin to comprehend genomic sequencing and how this impacts their own genetic and genomic decision-making.
Objective
To assess baseline genomic knowledge among adolescents and parents, examine its influence on decisions about genetic testing and sequencing, and identify opinions on appropriate age thresholds for youth participation in testing decisions.
Methods …
Improving The Transition From Pediatric To Adult Health Care In Massachusetts, Hanaa Hamoud
Improving The Transition From Pediatric To Adult Health Care In Massachusetts, Hanaa Hamoud
Capstones
No abstract provided.