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Partial Letter, Eunice J. Stockwell To Unidentified Friend, Eunice J. Stockwell

A.G. Wineman & Sons Records, and Wineman, Williams, Guice, and Stockwell et al Family Papers

In this letter, Eunice J. Stockwell writes to an unidentified friend to update her on the local news and how her genealogy research is going.

Letter, Charles F. Kauffman To Eunice J. Stockwell, Charles F. Kauffman

A.G. Wineman & Sons Records, and Wineman, Williams, Guice, and Stockwell et al Family Papers

In this undated letter, Charles F. Kauffman writes to Eunice J. Stockwell to provide some of the "data" he has on his Kauffman-Coffman family line as well has some information that he's collected on other Kauffman-Coffman lines that he has discovered during his genealogical research.

Notes On Scratch Paper

A.G. Wineman & Sons Records, and Wineman, Williams, Guice, and Stockwell et al Family Papers

This is a handwritten grocery list with some items crossed through. Items on the list include Rolls, Spic and Span Coupon, Celery, Milk, card for Sey[?]; Ajax Cleanser; Swifts

Advertisement For The "Kauffman-Coffman Lineages" Book

A.G. Wineman & Sons Records, and Wineman, Williams, Guice, and Stockwell et al Family Papers

This card advertises the publication of the "Kauffman-Coffman Lineages" book and describes the contents. Instructions on how to order are included and "York Penna." is written beneath Charles F. Kauffman's address.

Coffman Family Genealogy Per Mrs. Walter Tickell's Line

A.G. Wineman & Sons Records, and Wineman, Williams, Guice, and Stockwell et al Family Papers

This document traces the Coffman family line that includes Mrs. Walter Tickell (Linnie Power Tickell). Information from David Coffman's will is also included. Some handwritten notes are on the back of the document.

Introduction To Volume 9: Climate And Responsibility, Heather L. Scheuerman, Sylvia J. Whitney Beitzel

International Journal on Responsibility

No abstract provided.

Translating Higher Education Into Vietnamese: An Applied Linguistics Approach To Language Equity And Higher Education Access, Z.W. Taylor, Alan Do, Jase Kugiya, Tuan Le

Journal of Southeast Asian American Education and Advancement

One growing population of non-native English speakers in the U.S. education system are native Vietnamese speakers, yet no studies have examined how higher education communication could be made more accessible for Vietnamese speakers. As a result, this case study reports on human and machine translational linguistics work conducted in partnership with the University of Iowa focused on simplifying and translating English enrollment management information into Vietnamese. Findings suggest that the institution increased the clarity and accessibility of enrollment management information by using second-person pronouns, shorter sentence structures, clearer diction, and explanations of institution-specific jargon. Moreover, analyses of machine and human …

2018 Editor’S Introduction, Lauren M. Bowen

Undercurrents: A Journal of Undergraduate Student Composition

No abstract provided.

Artificial Intelligence In Dentistry: A Cross-Domain Bibliometric Analysis Of Technologies, Functional Applications, And Dental Specialties, Min Yee Ng

Articles in Press

No abstract provided.

Biphasic Remodeling And Trabecular-Cortical Uncoupling In The Jawbone During Antiresorptive Therapy And Medication-Related Osteonecrosis: A Quantitative Imaging Analysis, Jang-Jaer Lee

Articles in Press

No abstract provided.

Keratin 18 As A Cytoskeletal Regulator Of Epithelial—Mesenchymal Plasticity And Prognostic Risk In Oral Squamous Cell Carcinoma, Jean-San Chia

Articles in Press

No abstract provided.

Silencing The Mir-132/Sirt1 Axis Suppresses Nlrp3 Inflammasome Activation And Myofibroblast Differentiation In Oral Submucous Fibrosis, Sin-Jia Tseng

Articles in Press

No abstract provided.

Submicron Diamond-Assisted Irrigation Enhances Apical Biofilm Removal Under Sonic And Ultrasonic Activation: An Ex Vivo Study, Sung-Chih Hsieh

Articles in Press

No abstract provided.

Enhancing Ecg Classification Using Systematic Cubic Spline Control Points With Deep Neural Networks, Hussein Qahtan Khalaf, Abeer Tariq Maolood, Nor Shahida Mohd Shah

Engineering and Technology Journal

The healthcare industry has undergone substantial growth over the past few years. Despite the development of medical technology, the diagnosis of cardiac arrhythmia is still a significant challenge for modern diagnostic methods for correct and efficient classification of electrocardiogram (ECG) signals, especially in cases of class imbalance and the complexity of the arrhythmia. This study proposes a novel deep learning model where the class imbalance problem is addressed using the Synthetic Minority Oversampling Technique (SMOTE) and the effect of signal resolution on the classification is investigated using Cubic Spline (CS) interpolation and Lightweight Deep Neural Network (CSLWDNN). Both the MIT-BIH …

Solar-Driven Photocatalytic Ceramic Membrane Reactors For Paracetamol Degradation: Process Optimization, Transport Dynamics, And Preliminary Cyclic Reusability, Adel Zrelli, Asma Abdennebi, Manoj Chandra Garg, Fanghua Li

Engineering and Technology Journal

The use of membrane separation and heterogeneous photocatalysis together appears to be an innovative way to remove long-lasting pollutants such as paracetamol (PCT) from water. To overcome the limited process by understanding hindering the practical deployment of solar-driven photocatalytic membrane reactors (PMRs), this study proposes a process-engineering-centered framework for a low-cost, integrated ceramic PMR. A laboratory-scale system was developed using inexpensive red clay ceramic membranes modified by immobilizing TiO₂ (P25) for paracetamol degradation under natural sunlight and ultraviolet irradiation. Unlike previous studies mainly focused on material development, this work evaluates the coupled effects of TiO₂ loading, membrane inclination, …

Neural Network Modelling Of Magnetic Effects In Solid-State Transformer Performance Under Variable Magnetic Operating Conditions, Godfrey Murairidzi Gotora, Blessed Ziyambe, Emanuel Rashayi

Engineering and Technology Journal

Solid State transformers (SSTs) are pivotal for renewable energy integration and smart grids, yet their performance is critically limited by non-linear magnetic effects such as core losses, flux- density saturation, and magnetising-inductance drift, that conventional analytical methods and prior artificial neural network (ANN) studies have struggled to model simultaneously across the electrical, thermal and magnetic domains. This study develops and evaluates a unified multi-output ANN framework that predicts six SST performance indicators which are efficiency, power density, total harmonic distortion, temperature rise, core loss and magnetising inductance from six operating variables (switching frequency, duty cycle, load current, ambient temperature, input …

Experimental Investigation Of Mechanical Performance Of Glass/Epoxy Hybrid Composites Reinforced With Natural Fibers, Bestwn Omer, Gailan Ismail Hasan

Engineering and Technology Journal

The use of epoxy-based composites has increased significantly due to their wide range of applications across various industries. However, these composites often require enhanced mechanical properties tailored to specific applications through the incorporation of different types of reinforcements. In this study, the effect of natural fibers on the mechanical properties (flexural strength, tensile strength, and impact energy) of composites based on two types of epoxy resins (LR202 and Sikadur®-52 LP) was investigated using the hand lay-up method. Different reinforcement fibers (fiberglass, cotton, and jute) were incorporated at various percentages. The results indicate that, among composites reinforced with a single type …

Aquila-X 3.0: Modular High-Throughput Mobile Potable-Water Factory With Adaptive Pretreatment, Parallel Production Trains, Seawater Energy Recovery, Multi-Grade Outputs, And Concentrate-First Residual Management Research Conceptual Invention, Michael Victor Caldwell Mr.

Defensive Publications Series

AQUILA-X 3.0 is a transportable, modular, multi-barrier water-production platform designed to produce more independently verified potable water per deployable system than conventional mobile RO plants while maintaining safe operation, source-specific treatment, practical energy demand, maintainability, redundancy, and complete residual accountability.

The system does not depend on one miracle component. Its capacity comes from:

• Selecting the shortest safe treatment route for each characterized source.

• Removing grit, solids, oil, algae, and foulants before fine membranes.

• Using multiple independently isolatable production trains.

• Avoiding high-pressure RO when freshwater does not need desalination.

• Using dedicated high-pressure SWRO equipment and energy recovery when seawater does need …

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Identifying Pyle's Metaphyseal Dysplasia – An Incidental Finding Of Skeletal Pathology On A Dental Checkup, Shruthi Parthasarathy, Amudhan Azhagan, Arthisri Anandhi Sekar, Poongodi V, Ram Shankar

Chulalongkorn Medical Journal

Introduction:

Pyle's disease, also known as familial metaphyseal dysplasia, is a rare autosomal recessive genetic disorder that primarily affects the skeletal system, particularly in children and adolescents. Characterized by distinctive radiographic features such as Erlenmeyer flask deformity and metaphyseal widening, Pyle's disease often goes underdiagnosed due to its mild clinical manifestations.

Case report:

This case report details a 15-year-old female patient presenting with retained milk teeth and unerupted permanent teeth, alongside notable skeletal abnormalities including genu valgum and kyphosis. Clinical and radiographic evaluations revealed significant dental anomalies, including multiple impacted permanent teeth and mild dysmorphic facial features. Although genetic testing …

Beyond Lipid-Lowering: Pleiotropic Effects Of Statins In Inflammation, Coagulation, And Cell Proliferation – Mechanisms And Clinical Implications, Kasidid Lawongsa, Yutthana Pansuwan, Supanut Kumjan

Chulalongkorn Medical Journal

Statins are widely used lipid-lowering agents that significantly reduce cardiovascular morbidity and mortality through inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Beyond their cholesterol-lowering properties, increasing evidence demonstrates that statins exert several pleiotropic effects independent of lipid reduction. These effects include anti-inflammatory, anti-thrombotic, and anti-proliferative actions mediated primarily through inhibition of the mevalonate pathway and downstream signaling molecules such as Rho, Rac, and Ras. Experimental and clinical studies have suggested potential benefits of statins in various non-cardiovascular conditions, including autoimmune diseases, venous thromboembolism, sepsis-associated coagulopathy, and certain malignancies. In addition, pharmacoepidemiologic studies have provided insights into the real-world effects and …

Evaluation Of Mdm2 Mrna Expression According To Clinicopathological Characteristics In Oral Squamous Cell Carcinoma (Oscc) Patients, Tirta Wardana

Chulalongkorn Medical Journal

Background: The murine double minute 2 (MDM2) gene encodes an E3 ubiquitin ligase that targets p53 for degradation, thereby influencing the pathogenesis of oral squamous cell carcinoma (OSCC).

Objective. The present study investigates MDM2 mRNA expression and its association with clinical and pathological characteristics in OSCC patients.

Methods: We conducted an observational-analytical study using a cross-sectional design. The study involved 39 OSCC patients. RNA extraction, cDNA synthesis, and quantitative PCR (qPCR) were performed. We quantified relative MDM2 mRNA expression using the Livak method (2-ΔΔCT) and GenEX MultiD software version 6.0. Statistical significance was assessed using independent t-tests.

Results: Although no …

Factors Associated With Colorectal Cancer Screening Decision-Making Among Older Adults At The Comprehensive Geriatric Clinic, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Chalisa Thanapura, Nawasiri Siriprasert, Thacha Pithayapibulpong, Bhorn-Ake Manasvanich, Vichai Viriyautsahakul

Chulalongkorn Medical Journal

Abstract

Background: The incidence of colorectal cancer (CRC) in Thailand is constantly increasing, and is highest in individuals aged 60-75 years. However, the number of older individuals undergoing CRC screening remains suboptimal.

Objective: This study aimed to identify factors associated with CRC screening decision-making among Thai older adults attending the Comprehensive Geriatric Clinic at King Chulalongkorn Memorial Hospital. The secondary objective was to identify factors associated with the choice of screening method—colonoscopy versus fecal occult blood testing (FOBT)

Methods: A cross-sectional study was conducted using a data record form at the Comprehensive Geriatrics Clinic, King Chulalongkorn Memorial Hospital in Bangkok, …

Integrative Analysis Of Bioinformatics Databases To Identify Thyroid Cancer Drug Target Candidates, Desti Rahmawati, Putri Permata Suka Admanegara, Rista Yulianti, Siska Widiastuti, Wirawan Adikusuma, Brilliant Citra Wirashada, Rahmat Dani Satria, Darmawi Darmawi, Baik Heni Rispawati, Rockie Chong, Ilker Ates, Lalu Muhammad Irham, Petrina Theda Philothra

Chulalongkorn Medical Journal

Background: Thyroid cancer is an endocrine malignancy whose incidence continues to rise globally. Although thyroid cancer generally has a favourable prognosis, aggressive subtypes such as anaplastic thyroid cancer remain a therapeutic challenge. Drug repurposing strategies offer the opportunity to accelerate the development of therapies by utilising drugs already available and with an established safety profile.

Objective: This study aims to identify candidate thyroid cancer risk genes by analyzing data extracted from GWAS and PheWAS databases, and to evaluate their potential therapeutic relevance through drug repositioning

Methods: Significant gene variants were obtained from GWAS and PheWAS databases and functionally annotated …

The Mathematical Model Predicts Peripheral Blood Cd34+ Cell Yield And Blood Volume Processing For Peripheral Blood Stem Cell Apheresis., Rattaporn Vichitratchaneekorn, Kanokpol Siriphanthong, Kanokwan Chinbordee, Phandee Watanaboonyongcharoen, Ponlapat Ronjnuckarin

Chulalongkorn Medical Journal

Introduction: The accurate prediction of stem cell yields is important for planning peripheral blood stem cell (PBSC) collection. This study aimed to develop a formula forecasting required blood volume processing to ensure adequate CD34+ cell products.

Methods: Data from donors and patients who underwent PBSC apheresis conducted at a tertiary care hospital were reviewed. BD FACSCanto™ II and Navios EX flow cytometry machines were used to determine the pre-collection CD34+ cell counts (preCD34).

Results: Of 50 donors and 85 patients, 145 leukapheresis procedures were performed. Linear regression models accurately predicted absolute CD34+ cell yields from pre-apheresis values, supporting optimal procedural …

Ameliorative Effect Of Ethanolic Extract Of Nardostachys Jatamansi Against High Fat Diet Induced Dyslipidemia In Rats, Umanath Preethi, Govindaraj Sumathy, Nathiya Shanmugam

Chulalongkorn Medical Journal

ABSTRACT:

Background and objective: The present study aimed to evaluate the antioxidant and hypolipidemic effects of ethanol extract of Nardostachys Jatamansi (N.J) in a high-fat diet-induced obesity model in male Wistar albino rats.Materials and methods:36 male Wistar albino rats were randomly divided into six groups, each comprising six animals: Group I received a normal diet for 9 weeks, while Group II was fed a high-fat diet (HFD) for the same period. Groups III–VI were also given HFD throughout. From week 5, Group III received rosuvastatin (10 mg/kg), and Groups IV–VI were treated with Nardostachys Jatamansi. extract at 100, 200, and …

Machine Learning-Based Gene Signature Detection Highlights Cxcl12 As A Key Marker For Aml Prediction, Selahattin Alperen Uysal, Burçin Kaymaz

Chulalongkorn Medical Journal

Background: Acute myeloid leukemia (AML) is a severe hematologic malignancy marked by uncontrolled proliferation and impaired differentiation of myeloid cells, disrupting normal hematopoiesis and resulting in poor clinical outcomes. Conventional diagnostic approaches often lack the precision to accurately classify AML subtypes, necessitating the integration of advanced computational methods to improve diagnostic and therapeutic strategies.

Objectives: This study aimed to apply machine learning (ML) techniques to transcriptomic data in order to identify a concise and informative gene signature capable of distinguishing AML cases from normal samples. Additionally, the study sought to evaluate the performance of predictive models in supporting AML prediction …

Assessing The Reliability Of Machine Learning Models In Classifying Depression Severity Using Facebook Text, Keito Yoneyama

Chulalongkorn Medical Journal

Depression is a growing global issue that requires urgent attention, particularly in Thailand. Without timely intervention, it can lead to serious consequences such as health complications, reduced social participation, and even suicide. Consequently, there has been increased research focused on developing algorithms to identify and classify social media data according to depression severity. This study aimed to evaluate the extent to which such algorithms are a suitable tool for the preliminary classification of Thai Facebook text into different levels of depression severity. The methodology involved data collection through surveys and Facebook scraping, followed by data preprocessing, feature engineering, and model …

The Normative Status Of States' Obligations To Mitigate The Climate Crisis: Implications For The Right To Adequate Housing, Erna Dyah Kusumawati, Sasmini Sasmini

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The convergence of the global climate crisis, pursuant to the UNFCCC Paris Agreement and its implementing protocols as well as the fundamental right to housing has fundamentally disrupted established legal paradigms, necessitating a rigorous re-examination of the normative status of state obligations. This paper examines the scope of governmental responsibility to mitigate climate-induced threats to housing security. Drawing upon international human rights frameworks and contemporary legal discourse, the study interrogates the complex friction emerging at the intersection of environmental mandates and housing protections. Through a systematic analysis of the existing literature and recent developments in the international climate change framework, …

Territorial Representation In Fiscal Governance: A Comparative Constitutional Analysis Of Indonesia's Regional Representative Council And South Africa's National Council Of Provinces, Endah Yuniningsih, Deden Rafi Syafiq Rabbani

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

This article examines the institutional role of territorial chambers in fiscal governance through a comparative constitutional analysis of Indonesia's Regional Representative Council (DPD) and South Africa's National Council of Provinces (NCOP). While the DPD was established to strengthen regional representation following Indonesia's decentralization reforms, its legislative role in fiscal policymaking remains institutionally constrained. Existing scholarship has primarily focused on the DPD's constitutional status in debates on bicameralism, with comparatively little attention to how constitutional design shapes the role of territorial chambers in fiscal governance and intergovernmental fiscal relations. Using a normative legal research method that combines statutory, conceptual, and comparative …

Geoengineering And Criminal Liability Comparative Lessons For Penal Reform, Zico Junius Fernando, Deviana Yuanitasari, Chairul Huda, Muhammad Yamani, Arimbi Fajari Furqon

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Geoengineering has emerged as a controversial climate technology involving large-scale interventions such as cloud seeding, weather modification, and unregulated carbon capture. While these practices are promoted as solutions to climate change, they also generate significant ecological risks that remain largely unaddressed within criminal law frameworks. This article examines the absence of explicit criminal liability for geoengineering-related harms and explores how comparative legal experiences can inform future penal reform. This research uses normative research methods with several approaches, including comparative, conceptual, and futuristic approaches. The collected legal materials are analysed qualitatively, and content analysis is employed to classify and interpret relevant …