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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Ai-Driven Drug Innovation Research: Trends, Challenges, And Countermeasures, Tian Miao, Qi Zhou, Lianzheng Zhou, Weijun Xu, Siyuan Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Artificial intelligence (AI) is profoundly transforming the innovation paradigm, industrial ecosystem, and business model of drug research and development. In recent years, the global AI-driven pharmaceutical market has grown rapidly. Major economies, multinational pharmaceutical enterprises, and technology giants are accelerating their strategic deployment. AI pharmaceutical industry has entered a critical stage of transitioning from proof-of-concept to commercial-application. China attaches great importance to the integrated development of AI and the biopharmaceutical industry, but it still faces challenges, including data scarcity, talent shortages, algorithmic black-boxes, regulatory lag, and weak foundations. This study proposes measures from the aspects of data supply, talent cultivation, …

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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

2026issue10content

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Investigating Pathway Of China’S Rapid Rise In Science, Technology And Industry, Yongxiang Lu

Bulletin of Chinese Academy of Sciences (Chinese Version)

As a globally recognized manufacturing powerhouse and the world’s second-largest economy, China has achieved historic leaps in scientific, technological, and industrial innovation capacity. This study analyzes the drivers of China’s rapid rise in science, technology and industry from there dimensions: education, infrastructure, and manufacturing. In terms of education, China has built the world’s largest science, technology, engineering, and mathematics (STEM) talent training system. The number of graduates with Ph.D. degree in STEM is twice that of the United States, and the quality of higher education has been steadily improved. On infrastructure, China ranks first globally in power generation and has …

Artificial Intelligence For Scientific Research: Strategic Landscape And Development Recommendations, Jiaofeng Pan, Feng Zhang, Jing Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Artificial intelligence is currently driving the evolution of scientific research toward a “fifth paradigm” characterized by intelligence. Major global economies are elevating the integration of AI into scientific research (AI for Science, AI4S) to the level of national strategy, rapidly rolling out strategic plans and policy measures amidst intensifying global strategic competition in this field. Based on analyzing the typical paradigms and strategic value of AI4S, this study examines the global strategic landscape by focusing on major economies such as the United States, the European Union, and Japan; compares and analyzes their policy frameworks regarding organizational coordination, platform development, and …

Forging “The Backbone Of The Blue Sky”: Pathways For Enhancing Independent Innovation Capability Of China’S Commercial Aircraft Industry, Qianshu Shi, Chao Zhang, Quan Cheng

Bulletin of Chinese Academy of Sciences (Chinese Version)

Advancing indigenous innovation in China’s commercial aircraft industry is essential for strengthening the country’s high-end equipment manufacturing capabilities and enhancing the technological self-reliance of its aviation sector. China has achieved notable progress in key technological breakthroughs, industrial system development, and commercial operational validation. Nevertheless, gaps remain between China and the world’s leading aviation powers, owing primarily to an insufficient supply of original advances from fundamental research, underdeveloped mechanisms linking collaborative innovation activities, limited capacity for the independent iteration of core systems, and inadequate accumulation of lifecycle data. Strengthening fundamental aeronautical research is therefore critical to overcoming these constraints. Drawing on …

Breaking Through Bottleneck In Overseas Expansion Of China’S Commercial Aircraft: Pathways For Business Model Innovation, Mengru Dong, Chaofeng Huang, Chao Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The overseas expansion of China’s commercial aircraft is a strategic choice for building manufacturing power, transportation power, and aviation powerhouse. Business model innovation serves as a crucial means to enable these aircraft to overcome international competition barriers and accelerate their overseas expansion. Based on the analysis of the urgency of the overseas expansion of China’s commercial aircraft and the necessity of business model innovation, this study systematically reviews the main business models for the overseas expansion of global commercial aircraft, including the complete aircraft sales model, the collaborative operation model, and the full life cycle service model. Furthermore, based on …

Current Status, Challenges, And Countermeasures For Airworthiness Certification Of China’S Large Homegrown Aircraft, Liming Ge, Mingda Yang, Zixuan Liu, Yichen Wang, Jing Deng

Bulletin of Chinese Academy of Sciences (Chinese Version)

The airworthiness certification of domestically produced large aircraft serves as both a crucial foundation for achieving self-reliance and independent control over China’s aviation industry chain and a key support for deep participation in the governance of global civil aviation rules. Currently, the airworthiness certification system has taken initial shape, localized infrastructure networks are gradually improving, and the benefits of a super-large market are continuously being realized, effectively facilitating the successful large-scale commercial operation of the C919 airplane. The development of domestic large aircraft families places greater demands on certification resource coordination and airworthiness management throughout the aircraft life cycle. However, …

International Experiences, Lessons, And Implications For Development Of Commercial Aircraft Industry, Chaofeng Huang, Cuilin Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The commercial aircraft industry serves as a cornerstone for building a strong aviation country, a new engine driving economic growth, and a core carrier for upgrading the aviation industrial structure. Over more than 70 years of global industrial evolution, commercial aircraft development programs in most countries have encountered bottlenecks and withdrawn from the market, resulting in a duopoly dominated by the United States and Europe, which has accumulated abundant practical experience and historical lessons. At present, China’s commercial aircraft industry has entered a new phase of large‑scale production and international expansion. Nevertheless, it still faces challenges including bottlenecks in key …

Dual Helix Drive For High-Level Technological Self-Reliance And Self-Improvement: Systematic Interaction Between Strategic Scientists And The Chinese Spirit Of Scientists, Jianqiang Li, Side Hu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Achieving high-level technological self-reliance and self-improvement necessitates the cultivation of commensurate strategic soft power. This study aims to elucidate how strategic scientists and the Chinese spirit of scientists, through deep-seated “systematic interaction”, form a “dual helix engine” that propels the national innovation system toward an advanced stage. Drawing on complex adaptive systems theory, a three-layer dynamic interaction model is constructed comprising “value internalization–organizational empowerment – ecological co-evolution”. The findings indicate that strategic scientists serve as the personified carriers and strategic executors of the Chinese spirit of scientists. Through paradigm guidance, institutional creation, and cross-boundary catalysis, they translate spiritual values into …

Two Modes Of Sustainable Development Transition, Shuai Zhang, Dajian Zhu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Sustainable development has become a global consensus. Every country should carry out sustainable development transition. Due to large differences in development stages and the ecological impacts imposed on the Earth, developed countries and developing countries ought to adopt different modes of sustainable development transition. By using the Doughnut model as an analytical tool, which has made a significant impact at the forefront of sustainable development research, this paper thoroughly discusses the two modes of sustainable development transition. The Transition Mode of Developed Countries (Mode B) refers to transition from the outer circle to the middle circle of the Doughnut model. …

Resource Security Research In China In The New Era: Evolving Concepts, Paradigm Shifts, And Strategic Pathways, Dong Jiang, Jinwei Dong, Yanzhao Yang, Jingying Fu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Resource security serves as a critical foundation for safeguarding national security and underpinning high-quality socioeconomic development. Major geopolitical conflicts, such as the Russia–Ukraine conflict and the US-Israeli strikes on Iran, have intensified turbulence across global resource supply chains, positioning resource security as a central arena of strategic competition among nations. As a major consumer and trading power in global resource markets, China faces persistently high import dependence for critical mineral resources, and the pressure to ensure resource security amid the pursuit of high-quality development continues to mount. Against this backdrop, resource security is evolving from a narrow focus on supply …

Progress, Challenges, And Policy Recommendations For China’S Climate Investment And Financing Pilot Zones In Context Of Carbon Neutrality, Xianchun Tan, Zhaoyang Deng, Chenxu Wang, Zhe Peng

Bulletin of Chinese Academy of Sciences (Chinese Version)

To implement the decisions and arrangements of the Central Committee of the Communist Party of China and the State Council on addressing climate change and to channel more capital toward climate action, China launched its first batch of 23 climate investment and finance pilot areas in 2022. Through the end of 2025, this study tracks and assesses of pilot development, synthesizes innovative models, identifies major challenges, and proposes policy recommendations. The results show that the pilot areas have made solid progress, with more than 260 supporting policy documents issued and over 6 300 projects, representing total planned investment exceeding RMB …

China’S Semiconductor Supply Chain Landscape And Strategies For Enhancing Global Competitiveness, Su Zhang, Ziyan Yang, Yifan Sun, Yan Xia, Huijuan Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Against the backdrop of accelerating global digital transformation, intelligent upgrades, and intensifying geopolitical competition, the semiconductor supply chain has become the focal point of global technological, economic, and security dynamics. This study systematically examines the evolution of the global semiconductor supply chain, assesses security risks in China’s semiconductor industry, and analyzes the impact of China-US semiconductor decoupling using a hypothesis extraction approach. Based on these findings, it proposes strategic pathways to enhance China’s semiconductor competitiveness. Key findings include the following: (1) The global semiconductor supply chain exhibits both “regional concentration” and “industry fragmentation”. The US and Europe dominate upstream segments, …

Enterprise-Led Tackling Model For Core Technology In Key Fields Based On Think Tank Double Helix Method, Fan Wu, Chidong Zhang, Yining Li, Tongtong Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

As efforts to achieve breakthroughs in core technologies in key fields become increasingly systematic, optimizing the organizational models for such efforts has emerged as an important issue in national innovation governance. Existing studies have largely examined the identification of core technologies in key fields and their breakthrough mechanisms from individual perspectives, with insufficient attention to the structural relationship between technological characteristics and organizational models. To address this gap, this study applies the Think Tank Double Helix Methodology and conducts analyses at the levels of mechanism, impact, and policy. It develops a three-dimensional classification framework comprising strategic value (S), market value …

Murine Typhus In Georgia: Historical Context And A Probable Case Of Resurgence Where Previously-Thought Eradicated, Giovanni Mella-Velazquez, Christopher He, Bolanle Akinsola, Judson Miller

Journal of the Georgia Public Health Association

Background: Murine typhus, caused by Rickettsia typhi, is a flea-borne illness historically endemic to the southeastern United States, with initial cases reported in Atlanta, Georgia in 1913. Following vector control efforts, incidence declined significantly, and the disease was removed from the nationally notifiable disease list in 1987. While recent cases have been reported in select regions, murine typhus has not been documented in Georgia for decades. We present a pediatric case in Atlanta that may represent the first reported instance in nearly 40 years, suggesting possible reemergence in the Southeast.

Methods: We conducted a case report analysis of a pediatric …

Gli Weekly, October 20, 2026, Franke Global Leadership Initiative

GLI Weekly

BTC Deadlines Approaching -- GLI Course Requirements -- Spring Registration Schedule -- Multiple Course Offerings in Climate Change Studies -- NPAD 367: Leadership and Nonprofits -- CSD 222 - Introduction to Sound and Hearing -- GLI Advising: 1st-Year Advising Happening Now -- Mansfield Lecture Series: A Conversation with Ambassador Shigeo Yamada -- NACOE Lecture Series: Indigenous Knowledge as a Foundation for Wellness -- Montana-10 Scholarship Academic Coach Internship -- Empower Pack Building with the Missoula Food Bank -- Student Leadership Workshops: What Makes a Leader?

Physical Activity Guidelines' Impact On Cognition In Multiple Sclerosis: A Systematic Review And Meta-Analysis Of Randomized Clinical Trials, Tanner Murphy, Alexa Lauinger, Joseph Peters, Ethan Truong, Libak Abou

Student Publications

Purpose: This systematic review and meta-analysis aimed to determine the effects of meeting physical activity guidelines for people with multiple sclerosis (PAG-MS) on cognition in people with multiple sclerosis (MS). Meeting PAG-MS has shown to elicit numerous health benefits in people with MS; minimal work has examined the influence of PAG-MS on cognition.

Materials and methods: A systematic search was conducted in PubMed, EMBASE, Web of Science, SPORTDiscuss, Scopus, and PsycINFO. Two independent reviewers assessed included studies for eligibility, extracted data, and evaluated risk of bias. Randomized controlled trials (RCTs) including physical activity that met PAG-MS and assessed cognition were …

Walking With Families Through End-Of-Life Care And Grief, Julie B. Van Otterloo

Faculty Work Comprehensive List

"Loved ones are not giving up; they are choosing to support the patient in living their best life, focusing on quality, dignity, and comfort rather than continuing treatments."

Posting about hospice care from In All Things, a blog which highlights the shared faithful and orthodox Reformed Christian perspective of our writers, exploring how to fearlessly engage with every aspect of modern life—until all is made new.

Walking with Families Through End-of-Life Care and Grief

Amcf-1 Overexpression Enhances Motor And Physiological Outcomes In A Mouse Model Of Leigh Syndrome, Andrew Fanous

Summer Research Program Abstracts

No abstract provided.

Integrating Tacit And Explicit Knowledge Across Construction Projects: A Qualitative Evidence Synthesis Of Knowledge Transfer, Lessons Learned, And Organizational Learning, Felix M. Delmonte

Mechanical and Civil Engineering Faculty Publications

Abstract

Construction projects rely on knowledge distributed among temporary, multidisciplinary teams, firms, and lifecycle stages. Practical judgment often remains with experienced participants, while written accounts may omit the conditions and reasoning needed for later use. This research examines how construction scholarship explains the movement of project knowledge from capture through sharing and retrieval to reuse on another project. It treats these activities as distinct, and considers tacit expertise alongside explicit records, with attention to who contributes knowledge, who needs it, and where it must travel. The planned approach is a qualitative synthesis of published, peer-reviewed research from 2022–2026. The available …

Source Page Evaluation Of Local Rag Retrieval For Engineering Safety: Implications For Mechanical And Civil Engineering, Sherif Sorour, Areej El Mufti, Mohamed Nabawy, Anwar Sahbel

Civil Engineering

Industrial safety question answering requires access to the exact source material that supports an answer, not merely a related document. This study evaluates the retrieval stage of a local retrieval-augmented generation (RAG) system at the source page level. Eighteen documents on lockout/tagout, machine guarding, and personal protective equipment were prepared in raw, cleaned, and metadata-enriched forms. Best Matching 25 (BM25), latent semantic analysis (LSA), and reciprocal rank fusion (RRF) hybrid retrieval were tested on 54 questions: 36 answerable, 12 safety-related but unsupported, and 6 outside the covered topics. Raw BM25 achieved the highest mean reciprocal rank (0.492) and Hit@5 (0.722), …

Comparative Population Genomics Reveals Distinct Population-Specific Genetic Signatures And Candidate Drug Targets In Indian Tribal And Caste Populations, Mansi Patel, Krishna Lohana, Riya Singh, Reeshu Gupta

Human Biology Open Access Pre-Prints

Background: India harbors remarkable genetic diversity shaped by geographical isolation, endogamy, and distinct evolutionary histories. Such diversity contributes to population-specific disease susceptibility and therapeutic responses. However, systematic integration of comparative population genomics with computational drug discovery remains limited.

Methods: Comparative genomic datasets representing five populations (Kapu, Irula, Relli, Brahmin, and Yadav) were analyzed to identify population-specific genes. Functional annotation was performed to determine their biological relevance. Candidate proteins were subjected to structure-based virtual screening against libraries of approved drugs and bioactive compounds. The highest-ranking protein–ligand complexes were subsequently evaluated through molecular dynamics simulations to assess structural stability and binding behavior. …

Mitigating Nursing Student Stress Through Mindfulness Techniques, Mandy Mcguire

Group: Northern Arizona University School of Nursing, DNP Doctoral Papers

Undergraduate nursing students experience high levels of academic and psychosocial stress, which can negatively impact learning and well-being. National and international evidence indicate that a large proportion of nursing students report elevated stres throughout their education. The purpose of this Doctor of Nursing Practice project was to evaluate the effect of faculty-facilitated mindfulness techniques on undergraduate nursing students’ perceived stress over one academic semester. A repeated-measures approach was used, with students completing the Perceived Stress Scale (PSS-10) at baseline (week 1), mid-semester (week 7), and post-intervention (week 14). Faculty shared brief mindfulness techniques, including guided breathing, guided imagery, and reflective …

Digital Inclusion And Psychiatric Care For Adults Experiencing Homelessness: Barriers, Innovations, And Ethical Implications, Ramon A. Gambino Castanos

DNP and Student Works

Populations experiencing homelessness face disproportionately high rates of mental health illness, yet they remain among the most digitally excluded populations in current healthcare systems. As new digital health interventions like telehealth, mobile apps, and eHealth platforms become increasingly important to mental health care delivery, questions arise about their accessibility, feasibility, and ethical implications for unhoused individuals. This paper explores the intersection of digital inclusion and mental health care for adults experiencing homelessness, drawing on eight systematic reviews published between 2020 and 2025. The literature reveals significant barriers to digital access, including lack of devices, internet connectivity, digital literacy, and trust …

Improving Gut Health, Hydration, And Constipation Prevention In Elderly Long-Term Care Residents, Mendi A. Mbuan

Group: Nebraska Methodist College

Dehydration and constipation are prevalent and interrelated concerns among elderly residents in long-term care (LTC) settings, contributing to reduced quality of life and preventable complications. This quality improvement project evaluated a structured, evidence-based intervention aimed at improving hydration, supporting gut health, and reducing constipation. A pre- and post-intervention design was implemented over six weeks in a pilot unit (n = 15 residents). The intervention included staff education, daily hydration monitoring, bowel tracking using the Bristol Stool Form Scale, and non-pharmacological strategies such as hydration prompts and fiber-supportive practices. Descriptive statistics and paired-samples t tests (α = .05) were used to …

Supporting Best Practice Standards In Clinical Simulation Through Community Collaboration: An Exploration Of Impacts On Nursing Student Clinical Competency, Lindsay N. Dubois

Dissertations

Authentic patient representation is essential for preparing nursing students to provide quality care. This need is significant for populations impacted by legislative restrictions to healthcare. Additionally, inconsistent approaches in clinical simulation can hinder teaching and learning of valuable content. Nurses have extensive experience in ethics and social justice advocacy to improve health outcomes. Community collaborations help nurses better support their patients and novice learner competency. In 2022, clinicians and faculty collaborated to improve gender-inclusive representation in undergraduate nursing curricula and to educate learners about local resources. This standardized patient experience, focused on the care of a transgender and non-binary identifying …

October 2026, Office Of Research

Research Update

No abstract provided.

The Law Of General Average, Luca Anderlini, Joshua C. Teitelbaum

Georgetown Law Faculty Publications and Other Works

Part of a ship’s cargo is jettisoned in order to save the vessel and the remaining cargo from imminent peril. How should the loss be shared among the cargo owners? The law of general average, an ancient principle of maritime law, prescribes that the owners share the loss proportionally according to the respective values of their cargo. We analyze whether the law of general average is a truthful and efficient mechanism. That is, we investigate whether it induces truthful reporting of cargo values and yields a Pareto efficient allocation in equilibrium. We show that the law of general average is …