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The Hollywood Rap And Trap Culture Industry And Its Portrayal Of Crime, Youth Socialization, And Anti-Social Behavioral Norms, Ishika Sen Apr 2026

The Hollywood Rap And Trap Culture Industry And Its Portrayal Of Crime, Youth Socialization, And Anti-Social Behavioral Norms, Ishika Sen

Honors Theses

This thesis synthesizes and reflects on media effects and hip-hop studies to examine how the Hollywood rap/trap industry participates in the influence of normalization of crime and anti-social behaviors, substance use, and the sexualization of women among youth (ages 13–21). I integrate analytic evidence on media violence with lyric/content analyses of rap and critiques of the criminal justice system in hip-hop. Specific subtopics from my outline include: theoretical frameworks (media-violence, social learning, cultivation, cultural criminology); corporate marketing and social-media amplification; youth vulnerability; and three patterned domains which include substance abuse, gun violence, and the sexualization of women, often leading to …


Reinforcement Learning Improves Llm Accuracy And Reasoning In Disease Classification From Radiology Reports, Yishu Wei, Yi Lin, Adam Flanders, George Shih, Yifan Peng Apr 2026

Reinforcement Learning Improves Llm Accuracy And Reasoning In Disease Classification From Radiology Reports, Yishu Wei, Yi Lin, Adam Flanders, George Shih, Yifan Peng

Department of Radiology Faculty Papers

Accurate disease classification from radiology reports is essential for many applications. While supervised fine-tuning (SFT) of lightweight LLMs improves accuracy, it can degrade reasoning. We propose a two-stage approach: SFT on disease labels followed by Group Relative Policy Optimization (GRPO) to refine predictions by optimizing accuracy and format without reasoning supervision. Across three radiologist-annotated datasets, SFT outperformed baselines and GRPO further improved classification and enhanced reasoning recall and comprehensiveness.


Time And Dose Dependent Effects Of Adipose-Derived Stromal Vascular Fraction Exosomes On Human Dental Pulp Stem Cell Proliferation, Sylva Dinie Alinda, Anggraini Margono, Indah Julianto, Dini Asrianti Bagio Apr 2026

Time And Dose Dependent Effects Of Adipose-Derived Stromal Vascular Fraction Exosomes On Human Dental Pulp Stem Cell Proliferation, Sylva Dinie Alinda, Anggraini Margono, Indah Julianto, Dini Asrianti Bagio

Journal of Dentistry Indonesia

Background: Cell proliferation is essential for tissue repair and immunomodulation in regenerative dentistry. Adipose-derived stromal vascular fraction (AD-SVF) is a promising autologous source for tissue engineering. Its exosomes (AD-SVF Exo), as cell-free products stable under ischemic conditions, represent an ethical and attractive modality for dental tissue regeneration and broader regenerative applications. Prior study indicates that AD-SVF Exo can enhance human dental pulp stem cell (hDPSC) migration and proliferation, particularly at low concentrations, but their detailed time- and dose-dependent proliferative effects remain unclear. This study aimed to investigate the time- and dose-dependent effects of low-concentration AD-SVF Exo on hDPSC proliferation …


In Silico Model Of Musa Acuminata Stem As An Anticancer On Oral Squamous Cell Carcinoma Against Egfr, Nevrila Dewi Rachmayani, Amy Nindia Carabelly, I Wayan Arya Krishnawan Firdaus, Maharani Laillyza Apriasari, Juliyatin Putri Utami Apr 2026

In Silico Model Of Musa Acuminata Stem As An Anticancer On Oral Squamous Cell Carcinoma Against Egfr, Nevrila Dewi Rachmayani, Amy Nindia Carabelly, I Wayan Arya Krishnawan Firdaus, Maharani Laillyza Apriasari, Juliyatin Putri Utami

Journal of Dentistry Indonesia

Background: Oral squamous cell carcinoma (OSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR). Citral, eucalyptol, and caffeic acid phenethyl ester (CAPE), which are derived from Musa acuminata, have shown anticancer activity. This study evaluated the potential of citral, eucalyptol, and CAPE from Musa acuminata as anticancer agents for OSCC by targeting EGFR using an in silico approach.

Methods: Potential biological activity was predicted using Prediction of Activity Spectra for Substances (PASS) Online. Molecular docking was conducted with AutoDock Vina, and BIOVIA Discovery Studio was used to analyze binding affinity, interaction types, and bond …


Micro-Ct Evaluation Of Root Canal Transportation And Centering Ability In Mesial Canals Of Mandibular First Molars, Selen Ince Yusufoglu, Esma Saricam, Mert Ocak, Ferhat Geneci, Burak Bilecenoğlu Apr 2026

Micro-Ct Evaluation Of Root Canal Transportation And Centering Ability In Mesial Canals Of Mandibular First Molars, Selen Ince Yusufoglu, Esma Saricam, Mert Ocak, Ferhat Geneci, Burak Bilecenoğlu

Journal of Dentistry Indonesia

Background: This study aimed to evaluate canal transportation, centering ability, structure model index (SMI), surface area, and root canal volume changes in the mesial canals of mandibular first molars using micro-CT.

Methods: Twenty-four mandibular first molars with two separate mesial canals and moderate curvature were included. Teeth were scanned using micro-CT before instrumentation and randomly divided into three groups (N = 8). Root canals were prepared using OneShape, OneCurve, and Rotate file systems, followed by post-instrumentation micro-CT scanning (10µm/pixel resolution). Changes in canal volume, surface area, transportation, centering ability, and SMI were analyzed at the apical, middle, and …


Evaluation Of An Audiovisual Educational Tool With Reinforcement Messages For Orthodontic Patients: A 6-Month Randomized Controlled Trial, Laura Restrepo Quijano, Maria Paula Vasco Gomez, Natalia Hurtado Velasquez, Luis Fabian Benitez Moreno Apr 2026

Evaluation Of An Audiovisual Educational Tool With Reinforcement Messages For Orthodontic Patients: A 6-Month Randomized Controlled Trial, Laura Restrepo Quijano, Maria Paula Vasco Gomez, Natalia Hurtado Velasquez, Luis Fabian Benitez Moreno

Journal of Dentistry Indonesia

Background: Orthodontic treatment increases the risk of bacterial plaque accumulation; therefore, oral hygiene education is essential to prevent complications, but its impact is usually limited when it is not reinforced with effective tools. This study aims to evaluate an audiovisual educational tool with reinforcement messages, compared with a verbal explanation about the proper use of the orthodontic oral hygiene kit.

Methods: This was a randomized controlled trial that included 62 patients randomly assigned to an intervention group: 31 patients who received an educational video plus three reinforcement messages via WhatsApp, and a control group: 31 patients who received …


Sinus Formation As A Manifestation Of Chronic Periodontitis In Mandibular Anterior Region: A Report On 2 Cases, Anisha Kumari, Shikha Tewari Apr 2026

Sinus Formation As A Manifestation Of Chronic Periodontitis In Mandibular Anterior Region: A Report On 2 Cases, Anisha Kumari, Shikha Tewari

Journal of Dentistry Indonesia

Background: Periodontitis is defined as an inflammatory disease of the supporting tissues of the teeth caused by specific microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone. Clinical manifestations of Persistent chronic periodontitis may mimic varied clinical manifestations, including those of apical abscess and systemic involvement.

Case report: This report presents the management of an intraoral sinus mimicking a chronic apical abscess in the mandibular anterior region associated with deep periodontal pockets in two male patients in their early thirties. With careful clinical and radiological examination and ruling out of endodontic and systemic involvement, the …


Antibacterial And Antibiofilm Effects Of Ziziphus Mauritiana Leaf Extract Against Staphylococcus Aureus, Wiwiek Poedjiastoeti, Irvan Septrian Syah Putra Rasad, Felicia Klarissa Tanzil, Indrayadi Gunardi, Armelia Sari Widyarman Apr 2026

Antibacterial And Antibiofilm Effects Of Ziziphus Mauritiana Leaf Extract Against Staphylococcus Aureus, Wiwiek Poedjiastoeti, Irvan Septrian Syah Putra Rasad, Felicia Klarissa Tanzil, Indrayadi Gunardi, Armelia Sari Widyarman

Journal of Dentistry Indonesia

Background: Tooth extraction is a common dental procedure often complicated by postoperative infections, with Staphylococcus aureus as a key opportunistic pathogen. Rising antibiotic resistance and side effects of conventional antiseptics like chlorhexidine highlight the need for natural alternatives. This study evaluated the antibacterial and antibiofilm potential of 96% ethanol extract from Ziziphus mauritiana leaves against S. aureus.

Methods: The extract was prepared by maceration and tested in vitro using microdilution for minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against S. aureus ATCC 25923. Antibiofilm activity was assessed via crystal violet staining on mature biofilms, with …


Correlation Between Maxillary Morphology And Sinus Dimensions In Skeletal Class I, Ii, And Iii Subjects: A Comparative Study, Nida Shaikh, Dipti Shastri, Pradeep Tandon, Gyan Prakash Singh Apr 2026

Correlation Between Maxillary Morphology And Sinus Dimensions In Skeletal Class I, Ii, And Iii Subjects: A Comparative Study, Nida Shaikh, Dipti Shastri, Pradeep Tandon, Gyan Prakash Singh

Journal of Dentistry Indonesia

Background: This study aimed to evaluate variations in maxillary and sinus morphology and their correlations with skeletal malocclusion patterns using CBCT.

Methods: This retrospective study analyzed CBCT records of 70 subjects aged 17–40 years, divided into three groups: Skeletal Class I (N = 25), Class II (N = 25), and Class III (N = 20). Five maxillary skeletal and four sinus parameters were assessed. Intergroup comparisons were performed using one-way analysis of variance (ANOVA) followed by Tukey’s post hoc test. Correlations were evaluated using Pearson’s correlation test. Intra-observer reliability was assessed by re-measuring 8 randomly selected CBCT scans …


Retrospective Cbct Evaluation Of Missed Root Canals And Their Association With Periapical Lesions In A Makkah-Based Population, Mashael Alqahtani, Samia Mohamed Elsherief, Ibtesam Kamel Afifi Apr 2026

Retrospective Cbct Evaluation Of Missed Root Canals And Their Association With Periapical Lesions In A Makkah-Based Population, Mashael Alqahtani, Samia Mohamed Elsherief, Ibtesam Kamel Afifi

Journal of Dentistry Indonesia

Background: Missed root canals are common and can cause persistent periapical disease, making the assessment of their prevalence essential for improving diagnostic accuracy and treatment outcomes. This study aimed to investigate the prevalence of missed canals and evaluate their association with periapical lesions in root canal–treated teeth in the Makkah population.

Methods: This retrospective cross-sectional study analysed 815 cone-beam computed tomography scans obtained from Umm Al-Qura University between 2019 and 2024. Missed canals and their association with periapical lesions were assessed by two independent observers. Statistical analysis was performed using the chi-square test.

Results: Missed canals were …


Comparison Of Chatgpt, Claude Ai, And Dental Students In The Detection Of Artifacts On Panoramic Radiography, Elif Çeçen Erol, Ceren Aktuna Belgin, Gözde Serindere, Kaan Gunduz Apr 2026

Comparison Of Chatgpt, Claude Ai, And Dental Students In The Detection Of Artifacts On Panoramic Radiography, Elif Çeçen Erol, Ceren Aktuna Belgin, Gözde Serindere, Kaan Gunduz

Journal of Dentistry Indonesia

Background: Accurate radiographic diagnosis requires images obtained with proper technique. Artifacts are unwanted irregularities or densities not produced by the primary X-ray beam and may obscure anatomical details in radiographic images. This retrospective study aimed to evaluate the performance of ChatGPT, Claude AI, and intern dental students in detecting artifacts in panoramic radiographs (PRs).

Methods: Between January and December 2024, panoramic radiographs of 40 patients containing 74 artifacts (motion, mispositioning, airway/soft tissue, and foreign body/metal artifacts) were retrospectively evaluated. The artifact detection performance of ChatGPT-4.0, Claude AI 3.5 Sonnet, and intern dental students was subsequently evaluated and compared …


Oral Health Behaviors And Oral Health Status In Elementary School Children In East Kalimantan, Indonesia, Lia Hapsari Andayani, Amabelle Elisanditya, Abdul Gani Soulisa, Sri Lestari Apr 2026

Oral Health Behaviors And Oral Health Status In Elementary School Children In East Kalimantan, Indonesia, Lia Hapsari Andayani, Amabelle Elisanditya, Abdul Gani Soulisa, Sri Lestari

Journal of Dentistry Indonesia

Background: Children's oral health can be influenced by various factors, including health behaviors, dietary patterns, and oral health knowledge. This study aimed to determine the correlation between oral health behaviors and oral health status in elementary school children.

Methods: This cross-sectional study involved 182 elementary school children in Bontang, East Kalimantan, taken by convenience sampling. Health behavior data were acquired by 12-item questionnaires based on the WHO guideline. Examination of dental and oral health status was done by using the DMFT Index and OHI-S. Chi-square was used to determine the correlation between oral health behaviors and oral health …


Creating A Unique Hemoglobin-Based Oxygen Carrier, Clayton Fuller Apr 2026

Creating A Unique Hemoglobin-Based Oxygen Carrier, Clayton Fuller

Celebrating Scholarship and Creativity Day (2018-)

The purpose of this thesis is to explain the current state of alternative oxygen carriers and propose a new hemoglobin-based oxygen carrier (HBOC) as a blood substitute/ blood therapeutic. Blood donation has drawbacks: risk of spread of infection, short storage time, and blood typing, and the current shortage. There are several possible modifications for hemoglobin to create a carrier (HBOC) which address specific issues related to allowing free hemoglobin to exist extra cellularly. One issue to address is vasoconstriction caused by nitric oxide scavenging, which has been solved by increasing the molecular weight of the HBOC via (co)polymerization, or by …


The Effect Of Education Using The Lecture Method And Puzzle Games On The Level Of Knowledge And Attitude Toward Balanced Nutrition Among Students Of Sdn Pakintelan 01 In Gunung Pati District, Semarang City, Erlin Nurlina, Syifa Qolbiyah Nasir Apr 2026

The Effect Of Education Using The Lecture Method And Puzzle Games On The Level Of Knowledge And Attitude Toward Balanced Nutrition Among Students Of Sdn Pakintelan 01 In Gunung Pati District, Semarang City, Erlin Nurlina, Syifa Qolbiyah Nasir

Indonesian Journal of Public Health Nutrition (IJPHN)

Fulfilled nutritional needs play an important role at school age. The beginning of nutritional problems occurs due to knowledge factors, so it is necessary to implement efforts to provide information about balanced nutrition. Nutrition education research using lecture and puzzle game methods was conducted at SDN Pakintelan 01 aimed at determining changes in the level of knowledge and attitudes of students regarding balanced nutrition. The type of research is Quasy Experiment and uses a pretest-post test design with control group design. The sampling technique uses stratified random sampling. The number of samples of the control group given education (lecture method) …


Food Fortification Strategies To Address Micronutrient Deficiencies In Cambodia: A Scoping Review Of Policy Implementation, Industry Capacity, And Public Health Outcomes, Sokha Yem, Sreypeov Tun, Sokunthea Kem Apr 2026

Food Fortification Strategies To Address Micronutrient Deficiencies In Cambodia: A Scoping Review Of Policy Implementation, Industry Capacity, And Public Health Outcomes, Sokha Yem, Sreypeov Tun, Sokunthea Kem

Indonesian Journal of Public Health Nutrition (IJPHN)

Background: Micronutrient deficiencies remain a major public health challenge in Cambodia, with iron deficiency anaemia, iodine deficiency disorders, zinc deficiency, and vitamin A deficiency disproportionately affecting women of reproductive age and children under five. Food fortification—the deliberate addition of essential micronutrients to commonly consumed foods—has been widely recognised as a cost-effective population-level intervention to address nutritional gaps. Objective: To systematically map and synthesise existing evidence on food fortification strategies in Cambodia, focusing on policy implementation, industry production capacity and compliance, regulatory enforcement, and public health outcomes. Methods: A scoping review was conducted following the Arksey and O’Malley methodological framework and …


The Relationship Between Parenting Styles And Breakfast Habits With Adolescent Eating Behavior, Nailul Nufarohah, Siti Soraya, Hilda Carmitha Panjaitan Apr 2026

The Relationship Between Parenting Styles And Breakfast Habits With Adolescent Eating Behavior, Nailul Nufarohah, Siti Soraya, Hilda Carmitha Panjaitan

Indonesian Journal of Public Health Nutrition (IJPHN)

Adolescence is a critical transitional period requiring adequate and balanced nutrition to support optimal physical growth and psychosocial development. However, unhealthy Eating Behaviors such as skipping breakfast, consuming unbalanced diets, and frequent intake of foods high in sugar, salt, and fat are still commonly observed. Parenting styles and breakfast habits are considered important factors influencing adolescents’ Eating Behavior. This study aimed to analyze the relationship between parenting styles and breakfast habits with Eating Behavior among adolescents. This study employed a quantitative approach with a cross-sectional design conducted at SMK Negeri 62 Jakarta, South Jakarta. The population consisted of 578 active …


Fiber Content, Total Sugar, And Glycemic Index Of Jackfruit Seed And Pigeon Pea Flour Snack Bar, Dhiyaa Septi Kirana, Tesa Rafkhani Apr 2026

Fiber Content, Total Sugar, And Glycemic Index Of Jackfruit Seed And Pigeon Pea Flour Snack Bar, Dhiyaa Septi Kirana, Tesa Rafkhani

Indonesian Journal of Public Health Nutrition (IJPHN)

Diabetes Mellitus (DM) in Indonesia is the 7th leading cause of death. Diets high in sugar and glycemic index, and low in fiber are known to trigger hyperglycemia. Snack bars high in fiber and low in glycemic index are known to reduce blood glucose levels. This research aims to determine a snack bar formulation made from jackfruit seed and pigeon pea flour and analyze fiber content, total sugar, and glycemic index value. This study used a completely randomized design analyzing three different proportions of jackfruit seed and pigeon pea flour, namely F1 (30%:70%), F2 (40%:60%), and F3 (50%:50%) with two …


Genetic Variation In Slc6a4 And Cytochrome P450 Enzymes: Implications For Personalized Antidepressant Treatment In Major Depressive Disorder, Claudia Buda Apr 2026

Genetic Variation In Slc6a4 And Cytochrome P450 Enzymes: Implications For Personalized Antidepressant Treatment In Major Depressive Disorder, Claudia Buda

Harriet L Wilkes Honors College Theses

Depression is one of the most common psychiatric disorders worldwide, with a significant impact on quality of life and global health. Despite the widespread use of selective serotonin reuptake inhibitors (SSRIs) as first-line treatment, individual responses vary significantly due to genetic differences. Variations in the serotonin transporter gene (SLC6A4) and the cytochrome P450 (CYP450) enzyme family have been identified as key factors influencing the efficacy, metabolism, and tolerability of SSRIs. This thesis examines the impact of polymorphisms in SLC6A4 and CYP450 on SSRI pharmacodynamics and pharmacokinetics, explores their potential for guiding personalized antidepressant therapy, and discusses the ethical and practical …


Changing Pseudo-Nitzschia And Dinophysis Distributions In The North Sea And Western Approaches (Ne Atlantic) And Their Potential Use In Biodiversity Assessments, Matthew M. Holland, Eileen Bresnan, Martin Edwards, Matthew Faith, Clare Ostle, Rowena Stern, Paul Tett, Claire Widdicombe, Callum Whyte, Abigail Mcquatters-Gollop Apr 2026

Changing Pseudo-Nitzschia And Dinophysis Distributions In The North Sea And Western Approaches (Ne Atlantic) And Their Potential Use In Biodiversity Assessments, Matthew M. Holland, Eileen Bresnan, Martin Edwards, Matthew Faith, Clare Ostle, Rowena Stern, Paul Tett, Claire Widdicombe, Callum Whyte, Abigail Mcquatters-Gollop

School of Biological and Marine Sciences

Pseudo-nitzschia and Dinophysis are two commonly occurring phytoplankton genera along Europe’s Atlantic coast. Species within these genera can produce toxins that accumulate in shellfish and pose health risks if consumed. Sustained monitoring of shellfish growing waters has generated decades-long time-series for these two genera, which have been considered for use in statutory biodiversity assessments as proxies for diatoms and dinoflagellates. There is also evidence that distributions are shifting; It is important to document these changes to anticipate risks for shellfisheries, and higher trophic levels. We assessed whether Pseudo‑nitzschia and Dinophysis data could support statutory biodiversity assessments and quantified distributional change …


Catur Piwulang: The Concept Of Great Leaders In Javanese Paradigm, Nuri Puji Hastuti Apr 2026

Catur Piwulang: The Concept Of Great Leaders In Javanese Paradigm, Nuri Puji Hastuti

Paradigma: Jurnal Kajian Budaya

Leaders can be a key factor in determining whether a nation experiences a flourishing or declining period. However, numerous phenomena indicate that Indonesia is losing its great leaders. Based on this problem, this research aims to explain and describe the forms, meanings, and functions of catur piwulang as the concept of great leaders in the Javanese paradigm. A descriptive qualitative method has been used. The syntax consists of data collection, reduction, display data, and conclusion. Data validity was checked through the triangulation of theories, resources, and techniques. The forms of catur piwulang are 1) wewehono teken, teken wong kalunyon, …


Mauro Altamirano V. Attorney General United States Of America Apr 2026

Mauro Altamirano V. Attorney General United States Of America

2026 Decisions

Agency


Supporting Parents Of Young Children With Type 1 Diabetes Through Telehealth: Randomized Controlled Trial Of The Reducing Emotional Distress For Childhood Hypoglycemia In Parents Intervention., Susana R. Patton, Nicole Kahhan, Holly O'Donnell, David D. Williams, Mark Clements, Kimberly Driscoll Apr 2026

Supporting Parents Of Young Children With Type 1 Diabetes Through Telehealth: Randomized Controlled Trial Of The Reducing Emotional Distress For Childhood Hypoglycemia In Parents Intervention., Susana R. Patton, Nicole Kahhan, Holly O'Donnell, David D. Williams, Mark Clements, Kimberly Driscoll

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Parents of young children with type 1 diabetes (T1D) are vulnerable to experiencing fear of hypoglycemia (FH), an emotional condition that includes persistent and intense worry about hypoglycemia and/or use of unhealthful behaviors to avoid hypoglycemia. Despite greater uptake of continuous glucose monitors (CGMs) and automated insulin delivery systems, FH remains prevalent and under-addressed in parents of young children. As such, we developed Reducing Emotional Distress for Childhood Hypoglycemia in Parents (REDCHiP), a video-based telehealth intervention designed to reduce FH in parents by providing T1D education and teaching parents how to apply evidence-based strategies from cognitive behavioral therapy and …


Prevalence Of Musculoskeletal Pain Among Nursing Students In A Tertiary Care Teaching Institution In South Kerala, Ajas Sn, Nalam Middleton A, Asha Raby N Apr 2026

Prevalence Of Musculoskeletal Pain Among Nursing Students In A Tertiary Care Teaching Institution In South Kerala, Ajas Sn, Nalam Middleton A, Asha Raby N

Muthanna Medical Journal

Background: Musculoskeletal pain (MSP) is a common occupational health concern among nursing students due to physically demanding academic and clinical training. This study assessed the prevalence, severity, and risk factors of MSP among nursing students in South Kerala. Methods: A cross-sectional study was conducted at Mount Zion Nursing College, Adoor, from March–June 2025. Universal sampling included all undergraduate nursing students (N = 198), with 175 participants (response rate: 88%). Data were collected using a self-administered online questionnaire incorporating the Standardized Nordic Musculoskeletal Questionnaire. Analysis was performed using SPSS version 28 using descriptive statistics, t-tests, ANOVA with Tukey post-hoc tests, Chi-square/Fisher's …


Prevalence Of Polypharmacy And Its Association With Adverse Drug Effects Among Elderly Individuals In An Urban Field Practice Area Of A Tertiary Care Institution In South Kerala, Ajas Sn, Shameer Hakkim, Asha Raby N Apr 2026

Prevalence Of Polypharmacy And Its Association With Adverse Drug Effects Among Elderly Individuals In An Urban Field Practice Area Of A Tertiary Care Institution In South Kerala, Ajas Sn, Shameer Hakkim, Asha Raby N

Muthanna Medical Journal

Background: Polypharmacy (≥ 5 medications) is increasingly common among the elderly due to multimorbidity, longer life expectancy, and fragmented care, and is linked to adverse drug effects (ADEs). In urban Thiruvananthapuram, community-level evidence on its burden and ADE association is limited.This study was done to estimate the prevalence of polypharmacy among community-dwelling elderly and examine its independent association with self-reported ADEs. Methods: A community-based cross-sectional analytical study (March–December 2024) was conducted among 420 elderly individuals (≥ 60 years) selected via systematic random sampling. A validated interviewer-administered questionnaire (CVI = 0.94; ICC = 0.87) assessed medication use (past 30 days), ADEs, …


2026 April 30 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University Apr 2026

2026 April 30 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.


Comparison Of Chop And R-Chop For Treatment Non-Hodgkin Lymphoma, Yogyakarta, Indonesia: A Cost-Effectiveness Analysis, Woro Supadmi, Rizky Gustinanda, Lalu M. Irham, Riat El Khair Apr 2026

Comparison Of Chop And R-Chop For Treatment Non-Hodgkin Lymphoma, Yogyakarta, Indonesia: A Cost-Effectiveness Analysis, Woro Supadmi, Rizky Gustinanda, Lalu M. Irham, Riat El Khair

Pharmacology and Clinical Pharmacy Research

CHOP and R-CHOP are commonly used chemotherapy regimens for Non-Hodgkin Lymphoma (NHL). While R-CHOP has demonstrated clinical benefits, its higher cost raises concerns regarding economic efficiency, particularly in middle-income countries such as Indonesia. This study aimed to compare direct medical costs and clinical outcomes of CHOP and R-CHOP regimens among NHL patients treated at a national referral hospital in yogykarta. A retrospective cohort study was conducted using medical record data of NHL patients who received CHOP or R-CHOP chemotherapy at Dr. Sardjito General Hospital Yogyakarta, between 2020 and 2023, with follow-up extended until April 30, 2025. Clinical outcomes included overall …


Balanced Scorecard In Healthcare Facilities: A Ten-Year Review Of Strategies To Improve Organizational Effectiveness, Larasati Tunggadewi, Sofa Dewi Alfian, Auliya A Suwantika Apr 2026

Balanced Scorecard In Healthcare Facilities: A Ten-Year Review Of Strategies To Improve Organizational Effectiveness, Larasati Tunggadewi, Sofa Dewi Alfian, Auliya A Suwantika

Pharmacology and Clinical Pharmacy Research

The Balanced Scorecard (BSC) has increasingly been adopted as a strategic performance management framework within healthcare organizations. Evidence from the past decade shows varied implementation outcomes, shaped by institutional readiness, leadership commitment, and the maturity of health information systems. This narrative review synthesizes findings from 47 scientific articles selected through a systematic screening process, covering studies conducted in hospitals, primary health centers, and pharmacy units in Indonesia, Morocco, Iran, China, and other countries. The studies employed case study and descriptive cross-sectional designs using both quantitative and qualitative approaches. Overall, BSC implementation contributed to improvements in service performance across the financial, …


Exploring Protein-Protein Interactions: A Promising Avenue For Biomarker And Anti-Tb Drug Development, Rajwa Dwifauza Suryanto, Maritsa Widati Aqila Rumawan, Imam Adi Wicaksono Apr 2026

Exploring Protein-Protein Interactions: A Promising Avenue For Biomarker And Anti-Tb Drug Development, Rajwa Dwifauza Suryanto, Maritsa Widati Aqila Rumawan, Imam Adi Wicaksono

Pharmacology and Clinical Pharmacy Research

In 2023, tuberculosis (TB) reached its highest incidence with 8.2 million new cases reported by the World Health Organization (WHO). The virulence of Mycobacterium tuberculosis (MTB) is strongly governed by protein-protein interactions (PPIs) that regulate essential processes such as cell wall biosynthesis, immune evasion, and persistence. This study aims to map and analyze the mechanisms of key PPIs in MTB using a scoping review approach. Data was retrieved from PubChem and related literature with the keyword ``PPIs Network TB''. Our findings highlight crucial PPI-driven mechanisms, including the role of DprE1/DprE2 in arabinogalactan synthesis, VapB4/VapC4 in stress response and self-toxicity, ESX-1 …


Low To Moderate Intensity Home-Based And Online Exercise For Cognitive Health In Older Adults: A Narrative Review, Novita Salim, Melisa Intan Barliana, Anna Meiliana Apr 2026

Low To Moderate Intensity Home-Based And Online Exercise For Cognitive Health In Older Adults: A Narrative Review, Novita Salim, Melisa Intan Barliana, Anna Meiliana

Pharmacology and Clinical Pharmacy Research

Cognitive decline represents one of the most pressing public health challenges associated with global population ageing, prompting growing interest in accessible and scalable exercise-based interventions. This narrative review synthesizes evidence from 15 randomized controlled trials to compare the cognitive effects of 3 exercise modalities in older adults across varying cognitive and functional profiles: conventional aerobic and resistance training, exergame-based interventions, and dual-task or multicomponent training. Interventions were evaluated on their capacity to improve global cognition, executive function, working memory, and attention, with additional consideration of adherence, supervision format, and implementation feasibility. The evidence consistently demonstrates that dual-task and multicomponent training …


Igg4-Related Disease As An Uncommon Cause Of Myocarditis: A Case Report., Emily Ellis, Sarah Grebennikov, Rodolfo Jose Denadai Benatti Apr 2026

Igg4-Related Disease As An Uncommon Cause Of Myocarditis: A Case Report., Emily Ellis, Sarah Grebennikov, Rodolfo Jose Denadai Benatti

Heart and Vascular Articles

BACKGROUND: IgG-4-related disease (IgG4-RD) is a systemic fibroinflammatory disease that can affect any organ system. Myocarditis is a rare manifestation.

CASE SUMMARY: A 65-year-old woman with clinically diagnosed IgG4-RD, who had recently completed corticosteroid taper, presented with multiple admissions for recurrent chest pain and myocardial injury. Coronary angiography repeatedly showed preserved coronary anatomy, and initial transthoracic echocardiography showed preserved left ventricular systolic function. Subsequent transthoracic echocardiography showed rapid decline in ejection fraction, and cardiac magnetic resonance imaging (MRI) showed myocardial oedema, infarct scar, and patchy non-ischaemic fibrosis. A probable diagnosis of IgG4-RD myocarditis was made clinically based on medical history, …