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Plant-Derived Bioactives, The Gut-Brain Axis, And Neurodegenerative Diseases: Mechanistic Roles Of Diet-Microbiota Interactions, Ashley Reynolds, Ethan Glenn, Brigitte Lavoie, Suzanne L. Ishaq, Yanyan Li May 2026

Plant-Derived Bioactives, The Gut-Brain Axis, And Neurodegenerative Diseases: Mechanistic Roles Of Diet-Microbiota Interactions, Ashley Reynolds, Ethan Glenn, Brigitte Lavoie, Suzanne L. Ishaq, Yanyan Li

Pharmacy Faculty Scholarship

Diet is increasingly recognized as a potential upstream modulator of the gut-brain axis (GBA) through its effects on the microbiome, microbial metabolites, and host immune and endocrine responses. The GBA is a complex, bidirectional network connecting the gastrointestinal tract and central nervous system, with diet influencing microbial community structure and metabolic output. Plant-based diets, such as Mediterranean and MIND, have been associated with increased production of anti-inflammatory microbial metabolites and improved barrier function, while high calorie/low nutrient diets are often linked to increased immune activation and barrier dysfunction. However, while microbial metabolites, especially short-chain fatty acids, indoles, bile acids, and …


Nevada Health And Bioscience Asset Corporation V. State Of Nevada Ex Rel. Department Of Taxation And Nevada Tax Commission, 142 Nev. Adv. Op. (May 28, 2026), Collin Faught May 2026

Nevada Health And Bioscience Asset Corporation V. State Of Nevada Ex Rel. Department Of Taxation And Nevada Tax Commission, 142 Nev. Adv. Op. (May 28, 2026), Collin Faught

Nevada Supreme Court Summaries

The court held that contracting with a government entity does not prevent an otherwise qualifying charitable organization from receiving a sales and use tax exemption.


Maryland Reproductive Freedom And The Full Personhood Of Pregnant People, Margaret E. Johnson May 2026

Maryland Reproductive Freedom And The Full Personhood Of Pregnant People, Margaret E. Johnson

All Faculty Scholarship

Pregnant and birthing people are inappropriately criminalized. Such criminalization is for behavior during their pregnancy that would not otherwise be criminalized, including when there was no harm to the later born baby, and for birth outcomes like miscarriages and still births. Law supports criminalization in part because of the historic legal significance given to fetal “viability” as a demarcation between full personhood rights for pregnant people and the encroachment of fetal “personhood” on those rights. Focusing on Maryland’s new constitutional amendment for reproductive freedom, this essay examines how the new amendment offers promise in restoring the full personhood rights for …


The Relationship Between Musical Ability And Perceptual Skills For Speech Motor Learning In Young Adults, Emily Catmull May 2026

The Relationship Between Musical Ability And Perceptual Skills For Speech Motor Learning In Young Adults, Emily Catmull

Theses and Dissertations

Speech motor learning is the multimodal process of acquiring speech sounds. Speech motor learning is trained through speech-language pathologist intervention in individuals across the lifespan. Previous research has explored which factors can influence speech motor learning, such as musical experience or training, which is the subject of this study. Sixty young adult participants (four male, 56 female) were recruited as part of a larger study that examined four possibly influential factors: bilingualism, phonetic knowledge, perceptual skills, and musical experience. Since the adult population has already acquired all the speech sounds in English, learning was measured using nonnative consonant clusters. Participants …


Hypercapnic Respiratory Failure Secondary To Myxedema Coma: A Case Report, Carrine S. Kogulan, Oluwafemi Ajibola May 2026

Hypercapnic Respiratory Failure Secondary To Myxedema Coma: A Case Report, Carrine S. Kogulan, Oluwafemi Ajibola

Student Publications

Hypothyroidism affects a large subset of the population, with many undiagnosed. In iodine-sufficient regions, chronic autoimmune thyroiditis (Hashimoto’s) is the leading cause. Chronic, untreated hypothyroidism can result in multisystem complications, including cardiovascular disease, infertility, and respiratory failure. The most severe presentation, myxedema, is a medical emergency marked by altered mentation, ranging from lethargy to coma, hypothermia, and hypoventilation. Prompt recognition and treatment with thyroid hormone replacement are essential to improve outcomes. We present a case of hypercapnic respiratory failure secondary to myxedema coma. A 51-year-old female with morbid obesity (BMI 39.9 kg/m²) presented unresponsive, hypoxemic, and cyanotic, requiring emergent intubation. …


Widespread Concern Over Gas Prices In Nh As Consumer Confidence Shows Sudden Slump 5/28/2026, Unh Survey Center May 2026

Widespread Concern Over Gas Prices In Nh As Consumer Confidence Shows Sudden Slump 5/28/2026, Unh Survey Center

All UNH Survey Center Polls

Six in ten New Hampshire residents are worried about paying for gas and believe gasoline prices will rise over the next twelve months. Two-thirds believe President Trump is very responsible for the increase in gasoline prices. As gas prices increase, Granite Staters are less positive about their personal finances compared to a year ago and many expect to be worse off a year from now. New Hampshire residents are also downbeat on the national economy, as nearly half anticipate bad times over the next year and two-thirds believe the economy is getting worse.


Most Mainers Worried About Gas Prices, Nearly Half Have Driven Less Amid Price Spike 5/28/2026, Unh Survey Center May 2026

Most Mainers Worried About Gas Prices, Nearly Half Have Driven Less Amid Price Spike 5/28/2026, Unh Survey Center

All UNH Survey Center Polls

Majorities of Mainers are worried about the cost of gasoline and believe gas prices will continue to rise. Nearly half have limited their travel because of the price increase, while more than a third have cut spending on non-essentials in their life. More than three-quarters believe oil companies and President Trump are very or somewhat responsible for the rise in the price of gasoline. Mainers are generally pessimistic about the economy; half expect bad economic times over the next year and nearly two-thirds believe the economy is getting worse. More than half of Mainers say their personal finances have declined …


The Importance Of Career And Retirement Services For Student Athletes, Vincent R. Giuliano May 2026

The Importance Of Career And Retirement Services For Student Athletes, Vincent R. Giuliano

Masters Projects

There are hundreds of thousands of collegiate student-athletes competing in organized sports in the NCAA. Research shows the different resources that are available to them during their time competing, as well as how sports can open different opportunities for them during their competitive years. However, once this is over, an individual may realize they spent their time becoming an athlete and not enough time on their holistic well-being and professional development due to time constraints, identity engulfment, etc. While institutions do well in nurturing students during their competitive years, they lack in considering the retirement of these student-athletes. This project's …


Modulating Electronic Structure With Linearly Fused Pyrazine Units For High-Voltage And Stable Zinc-Organic Batteries Cathode, Min-Jian Zhao, Li-Bin Zhang, Jin-Tao Wang, Kun Ding, Hai-Mei Liu, Yong-Gang Wang May 2026

Modulating Electronic Structure With Linearly Fused Pyrazine Units For High-Voltage And Stable Zinc-Organic Batteries Cathode, Min-Jian Zhao, Li-Bin Zhang, Jin-Tao Wang, Kun Ding, Hai-Mei Liu, Yong-Gang Wang

Journal of Electrochemistry

High-voltage n-type organic cathode materials are critical for constructing zinc-organic batteries (ZOBs) with high energy density and long cycle life. However, the intrinsically unfavorable electronic structures and relatively high LUMO energy levels of most n-type materials often lead to sluggish kinetics, high solubility, and suboptimal discharge voltages (< 0.8 V). Here, we design a small molecule, quinoxalino[2’,3’:5,6]pyrazino[2,3-f][1,10]phenanthroline (DPQP), as a ZOB cathode by introducing locally electron-deficient motifs into the conjugated backbone of aromatic compounds. The linearly fused pyrazine units extending the pyrazine–benzene framework effectively optimize the electronic structure, thereby significantly enhancing the discharge voltage. Meanwhile, the expanded π-conjugated plane suppresses dissolution and accelerates charge-transfer kinetics. Benefiting from these features, the DPQP electrode exhibits an exceptional increase in average operating voltage from 0.61 V to 1.07 V (vs. Zn2+/Zn) at 0.1 A·g–1, with an overpotential of only 140 mV. Notably, no discernible voltage decay occurs as the current density increases, indicating rapid and highly reversible redox kinetics. Furthermore, the DPQP cathode delivers outstanding cycling stability, maintaining over 2000 h of continuous operation at 0.1 A·g–1 …


Pregnancy Outcomes After In Utero Exposure To Immune Checkpoint Inhibitors, Sarah Diane Hmaidan, Roni Nitecki Wilke, Jeffrey A How, Terri L Woodard, Pamela T Soliman, Laurie J Mckenzie May 2026

Pregnancy Outcomes After In Utero Exposure To Immune Checkpoint Inhibitors, Sarah Diane Hmaidan, Roni Nitecki Wilke, Jeffrey A How, Terri L Woodard, Pamela T Soliman, Laurie J Mckenzie

Faculty, Staff and Students Publications

Importance: Immune checkpoint inhibitors (ICIs) have transformed the management of cancers affecting reproductive-age patients, yet their impact on pregnancy outcomes remains incompletely understood. We describe two cases of maternal and fetal outcomes associated with ICI exposure during pregnancy and present a comprehensive literature review.

Methods: A retrospective chart review was conducted at MD Anderson Cancer Center (1 January 2015 to 31 December 2024) to identify patients exposed to ICIs during pregnancy. Clinical data including cancer type, treatment timing, pregnancy course, and maternal and neonatal outcomes were collected. A narrative literature review was also performed using PubMed to identify reported cases …


Development Of A Second-Generation Rarα Selective Antagonist As An Orally Bioavailable, Effective, Safe, And Reversible Male Contraceptive, Ehfazul Haque, Taimeng Liang, Narsihmulu Cheryala, Feng Li, Henry L Wong, Gunda I Georg May 2026

Development Of A Second-Generation Rarα Selective Antagonist As An Orally Bioavailable, Effective, Safe, And Reversible Male Contraceptive, Ehfazul Haque, Taimeng Liang, Narsihmulu Cheryala, Feng Li, Henry L Wong, Gunda I Georg

Faculty, Staff and Students Publications

We report the design and SAR studies of benzopyran-, benzofuran-, and benzothiophene-derived inhibitors of the retinoic acid receptor alpha (RARα) for male contraception. SAR studies identified critical features influencing activity, such as the optimal positioning of antagonism moieties and substituents, leading to the discovery of (S)-4-(5-(2,8-dimethyl-5-(p-tolyl)-2H-chromen-3-yl)-1H-pyrrol-2-yl)­benzoic acid (compound 23). Compound 23 is a highly potent RARα inhibitor (IC50 = 0.051 nM) with excellent selectivity (>1650-fold over RARβ and >1960-fold over RARγ) and ADMET properties. Compound 23 is orally bioavailable and reduces sperm counts in mice for a full male contraceptive effect …


Bridging The Justice Gap: A Comparative Study Of Legal Aid Marketing In Canada, Australia, And The United States, Farah O. Haq May 2026

Bridging The Justice Gap: A Comparative Study Of Legal Aid Marketing In Canada, Australia, And The United States, Farah O. Haq

Student Theses and Dissertations

Access to justice remains a central challenge across legal systems, particularly for immigrants and refugees, Indigenous communities, and survivors of domestic violence. While legal aid organizations play a critical role in bridging this gap, their effectiveness increasingly depends on how clearly and compassionately they communicate legal information online to their target audience. This thesis conducts a comparative content analysis of nine nonprofit legal aid organizations in the United States, Canada, and Australia, three countries united by a common law tradition but divided by the communication barriers their communities face, examining 180 social media posts and nine websites through the lens …


Nyu Cardozo Robotaxi Symposium, Heyman Center On Corporate Governance, The Guarini Center On Environmental, Energy & Land Use Law May 2026

Nyu Cardozo Robotaxi Symposium, Heyman Center On Corporate Governance, The Guarini Center On Environmental, Energy & Land Use Law

2026 Event Invitations

In the past year, interest in robotaxis in New York has surged. Last summer, Waymo started testing its vehicles on Manhattan streets. In January, Governor Hochul proposed automated vehicle pilot programs upstate. But in February, she withdrew her proposal under pressure. And in March, Waymo’s testing permit expired. The future of robotaxis in New York is an open question. This Symposium will explore the legal and policy issues that robotaxis raise. Our goal is to enrich the public conversation by bringing together experts from around the country to share their knowledge and experience. There will be two panels: one on …


A Political Ecology Of The Orang Rimba's Struggle And Existence In Jambi, Indonesia, Aditya Dipta Anindita, Arya Hadi Dharmawan, Soeryo Adiwibowo, Didik Suharjito May 2026

A Political Ecology Of The Orang Rimba's Struggle And Existence In Jambi, Indonesia, Aditya Dipta Anindita, Arya Hadi Dharmawan, Soeryo Adiwibowo, Didik Suharjito

Forest and Society

Since the 1970s, forest conversion in the name of development has encroached upon the living spaces of the Orang Rimba, a forest-dwelling indigenous group in Jambi Province, Indonesia. Some of the forest areas, which serve as the cultural and livelihood foundation for this hunter-gatherer community, have been transformed into transmigrant settlements and oil palm plantations, while the remaining forests were designated as a National Park in 2000. Although they still have access to the national park, many Orang Rimba have built their livelihoods among the oil palm trees—not as owners or workers, but believing that these lands are their ancestral …


Richmond Agitation-Sedation Scoring Implementation In A Critical Access Hospital, Jasmine A. Hobbs May 2026

Richmond Agitation-Sedation Scoring Implementation In A Critical Access Hospital, Jasmine A. Hobbs

Doctor of Nursing Practice Posters and Presentations

Mechanically ventilated patients who are boarding in rural emergency departments face an increased risk of inconsistent sedation management due to the lack of standardized protocols and the extended transfer times to higher levels of care. The variability in sedation practices can lead to both under- and over-sedation, which negatively affects patient comfort, safety, and clinical outcomes. Research suggests that sedation protocols incorporating the Richmond Agitation-Sedation Scale (RASS) can shorten mechanical ventilation duration and improve clinical outcomes. The purpose of this project was to evaluate the effectiveness of a targeted educational intervention on improving nursing knowledge and comfort with the RASS …


The Price Of The Pitch: When Repetitive Stress Can Cause Anatomical Developmental Abnormalities, Oswald Ramos Tuarez May 2026

The Price Of The Pitch: When Repetitive Stress Can Cause Anatomical Developmental Abnormalities, Oswald Ramos Tuarez

Advocate GME

CASE HISTORY: 17 yo right-handed softball player presented to training room after a shoulder subluxation during overhead throw at scrimmage. She reported continued popping sensation and pain with overhead throws that did not improve with rest. She was able to continue underhand pitching and hitting with minimal pain. Minimal pain at rest. Started physical therapy but continued pain and feeling of grinding with overhead activities. Denied previous trauma, numbness, tingling or upper extremity weakness.

PHYSICAL EXAM: A0x3. Neck: No tenderness to palpation on the cervical spine, FROM of cervical spine. Negative spurling's. Right shoulder: FROM, Pain at end ROM with …


“It's Because Of Me – I Made Myself Get Here”: First-Generation College Students In Stem Motivations For, And Experiences With, Academic Advising, Desiree Forsythe, Amy C. Moors, Quaylan Allen, Jeremy L. Hsu May 2026

“It's Because Of Me – I Made Myself Get Here”: First-Generation College Students In Stem Motivations For, And Experiences With, Academic Advising, Desiree Forsythe, Amy C. Moors, Quaylan Allen, Jeremy L. Hsu

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Academic advising plays a major role in shaping undergraduate life sciences students’ experiences through college. However, despite the critical nature of advising, there have been relatively few studies examining students’ experiences with advising and how these experiences may influence their academic journeys. Here, we investigate first-generation college students’ experiences with academic advising in biology and throughout STEM. Through the lens of community cultural wealth, we found several themes such as balancing independence and pressures to succeed, identity as a source for empowerment and motivation, wanting reassurance and support from advisors, as well as negative outcomes during interactions with advisors. We …


Movement, Residency, And Behavioral Plasticity Of Reef Manta Rays In The Samarai Islands Of Papua New Guinea, Anna Knochel, Joanna Harris, Shannon Murphy, Annie Murray, Guy M.W. Stevens, Mark Erdmann May 2026

Movement, Residency, And Behavioral Plasticity Of Reef Manta Rays In The Samarai Islands Of Papua New Guinea, Anna Knochel, Joanna Harris, Shannon Murphy, Annie Murray, Guy M.W. Stevens, Mark Erdmann

School of Biological and Marine Sciences

The reef manta ray (Mobula alfredi) is a highly mobile pelagic marine ray found throughout the tropical and subtropical waters of the Indo-Pacific, but investigation into their behavior and ecology within Papua New Guinea has not been previously undertaken. Furthermore, the home range, dispersal characteristics, and inter-seasonal fine-scale habitat use of this species is limited. To address these data gaps and investigate the vertical and horizontal habitat use of a previously unstudied population, SPLASH10-F-321A pop-off archival satellite tags were used to track ten adult individuals from 4–181 days between 2016–2018 across two distinct monsoonal periods in the Samarai Islands of …


Exploring Opportunities To Integrate Climate Change Into Gross National Happiness For Bhutan And Its Application For Global Wellbeing-Centred Climate Resilient Development, Tashi Dorji, Angus Morrison-Saunders, David Blake May 2026

Exploring Opportunities To Integrate Climate Change Into Gross National Happiness For Bhutan And Its Application For Global Wellbeing-Centred Climate Resilient Development, Tashi Dorji, Angus Morrison-Saunders, David Blake

Research outputs 2022 to 2026

Climate change poses an increasing threat to human wellbeing, but despite this intricate relationship, addressing climate change rarely mainstreams wellbeing objectives. This study explores opportunities to integrate climate change into Bhutan’s development philosophy of Gross National Happiness (GNH) and examines how this experience can inform a wellbeing-centred global application through Climate Resilient Development (CRD). Using a qualitative design combining semi-structured interviews with 41 policy influencers in Bhutan, document analysis, and literature synthesis, this study identifies two complementary points of integration. The first involves identifying and then embedding climate-wellbeing stressors into the 9 domains and 33 GNH indicators used in the …


Powerful Radio Sources In The Southern Sky. Iv. Observations Of The G4jy-3cre Catalog With The Australian Square Kilometre Array Pathfinder, Siegfried A. Gawenda, Juan P. Madrid, Francesco Massaro, Sarah V. White, C. C. Cheung, C. Mazzucchelli, Abigail García-Pérez, I. Andruchow, V. Chavushyan, Ralph P. Kraft May 2026

Powerful Radio Sources In The Southern Sky. Iv. Observations Of The G4jy-3cre Catalog With The Australian Square Kilometre Array Pathfinder, Siegfried A. Gawenda, Juan P. Madrid, Francesco Massaro, Sarah V. White, C. C. Cheung, C. Mazzucchelli, Abigail García-Pérez, I. Andruchow, V. Chavushyan, Ralph P. Kraft

Physics & Astronomy Faculty Publications

A recent 2023 paper by Massaro et al. introduced the G4Jy-3CRE, a new catalog of the brightest radio sources in the Southern Hemisphere that serve as a southern equivalent to the Third Cambridge Catalog Revised (3CR). The G4Jy-3CRE catalog selected 264 sources from the GLEAM-4Jy survey based on the same criteria used to select the sources in the 3CR. In this paper, we present new Australian Square Kilometre Array Pathfinder (ASKAP) continuum imaging of the G4Jy-3CRE catalog. We use the three most recent data releases from the Rapid ASKAP Continuum Survey (RACS), covering the sky south of +30° decl.: RACS-low1, …


(Co,Ni,Mn,Cu,Zn)O High-Entropy Oxide Nanotubes As Efficient Bifunctional Electrocatalyst For Oxygen Evolution And Hydrazine Oxidation Reactions, Pan-Yan Chen, Wan-Wan Wu, Heng Bian, Wei-Wei Li, Xin-Sheng Zhao, Lu Wei May 2026

(Co,Ni,Mn,Cu,Zn)O High-Entropy Oxide Nanotubes As Efficient Bifunctional Electrocatalyst For Oxygen Evolution And Hydrazine Oxidation Reactions, Pan-Yan Chen, Wan-Wan Wu, Heng Bian, Wei-Wei Li, Xin-Sheng Zhao, Lu Wei

Journal of Electrochemistry

High-entropy oxides (HEOs) present significant scientific challenges in both design and synthesis due to their multielement and high-entropy nature, which involves complex combinations of multiple metal cations and oxygen anions, typically arranged in equimolar ratios to achieve structural stability. Herein, one-dimensional (Co,Ni,Mn,Cu,Zn)O high-entropy oxide nanotubes (HEO-NTs) are fabricated by means of a gradient electrospinning strategy with a tailored polyvinyl alcohol (PVA) molecular weight distribution and controlled pyrolysis. Benefiting from the HEO features and the synergistic effect of multicomponent sites, the as-synthesized (Co,Ni,Mn,Cu,Zn)O HEO-NTs exhibit exceptional bifunctional electrocatalytic activity for the oxygen evolution and hydrazine oxidation reactions (OER/HzOR). This study offers …


An Ecological Survey Of Algal Species In The Sawyer River, Al-Muthanna Governorate, Iraq, Rasha.H. R. Al-Miawi, Hiafaa A.J. Al-Barakat, Alaa Jabar Mahmoud May 2026

An Ecological Survey Of Algal Species In The Sawyer River, Al-Muthanna Governorate, Iraq, Rasha.H. R. Al-Miawi, Hiafaa A.J. Al-Barakat, Alaa Jabar Mahmoud

Muthanna Medical Journal

Given the global changes in climate, especially the drought conditions Iraq has recently experienced, along with the severe water shortage, this study sought to develop both quantitative and qualitative methods and strategies for phytoplankton (excluding diatoms) as key indicators to protect ecosystems, boost their resilience, and promote sustainability. sites were chosen for the most prominent cities A number of samples were selected from three sites (Al-Dahara region, Al Jarukhi Bridge, Al-Ghanim area), located on the Al-Sawyer River, which is the most important branch of the Euphrates River in the Al-Muthanna Governorate in southern Iraq in 2024 the species that was …


A Review Of Enhanced Recovery After Surgery In Kidney And Liver Transplantation And Outline Of The Newcastle Eras Protocols, E. Bonner, C. Scuffell, F. Dowen, L. Macdougall, J. Fabes May 2026

A Review Of Enhanced Recovery After Surgery In Kidney And Liver Transplantation And Outline Of The Newcastle Eras Protocols, E. Bonner, C. Scuffell, F. Dowen, L. Macdougall, J. Fabes

Peninsula Medical School

Although Enhanced Recovery after Surgery (ERAS) is now common practice across various surgical specialties, the adoption of its principles has only recently gained momentum in liver and kidney transplantation. The publication of relevant ERAS guidelines in these specialties has undoubtedly facilitated the assimilation of evidence in support of ERAS components, the paucity of which had been viewed as a barrier to the implementation of ERAS in transplantation. In conjunction, institutionally-developed ERAS pathways have provided pragmatic examples of how these principles can be adopted within transplant practice. In this article, we summarise the current recommendations and underlying evidence for key components …


The 2026 Fifa World Cup: Communicable Disease Risks And Advice For Visitors To Canada, The United States, And Mexico, Álvaro A Faccini-Martínez, Daniel Grisales-Nieto, Florencia Escarrá, Pasesa Pascuala Quispe-Torrez, Francisco Javier Membrillo, Tomás Orduna, Susana Lloveras, Tânia S S Chaves, Miguel M Cabada, Cecilia Perret, René Echavarría, Ana F Ribeiro, Melinda Tanabe, Fernando Bazzino, Maximiliano Ramirez, Baruch Diaz, Karen Mirna Loro Morejón, Karen Daly, Reinaldo Rosas, Maria Belen Lopez, Cristina Miranda, Marisa Liliana Fernandez, Yasemin Özsürekçi, Wasin Matsee, Yenddy Carrero, Cristian Biscayart, Sergio Cimerman, Maria L Avila-Aguero, Roberto Debbag, Jose Brea, Alejandro Risquez, Jaime David Acosta-España, Rolando Ulloa-Gutierrez, Carlos Espinal, Carlos N Torres-Martinez, Marta González-Sanz, Aula Abbara, Jill Weatherhead, Mario Masana May 2026

The 2026 Fifa World Cup: Communicable Disease Risks And Advice For Visitors To Canada, The United States, And Mexico, Álvaro A Faccini-Martínez, Daniel Grisales-Nieto, Florencia Escarrá, Pasesa Pascuala Quispe-Torrez, Francisco Javier Membrillo, Tomás Orduna, Susana Lloveras, Tânia S S Chaves, Miguel M Cabada, Cecilia Perret, René Echavarría, Ana F Ribeiro, Melinda Tanabe, Fernando Bazzino, Maximiliano Ramirez, Baruch Diaz, Karen Mirna Loro Morejón, Karen Daly, Reinaldo Rosas, Maria Belen Lopez, Cristina Miranda, Marisa Liliana Fernandez, Yasemin Özsürekçi, Wasin Matsee, Yenddy Carrero, Cristian Biscayart, Sergio Cimerman, Maria L Avila-Aguero, Roberto Debbag, Jose Brea, Alejandro Risquez, Jaime David Acosta-España, Rolando Ulloa-Gutierrez, Carlos Espinal, Carlos N Torres-Martinez, Marta González-Sanz, Aula Abbara, Jill Weatherhead, Mario Masana

Faculty, Staff and Students Publications

No abstract provided.


Unbiased Niche Labeling Maps Immune-Excluded Niche In Bone Metastasis, Tianhong Pan, Yi-Hsuan Wu, Yujiao Han, Jun Liu, Igor L Bado, Weijie Zhang, Ling Wu, Yang Gao, Xiaoxin Hao, Liqun Yu, Xuan Li, David G Edwards, Hilda L Chan, Sergio Aguirre, Michael Warren Dieffenbach, Elina Chen, Siyue Wang, Yichao Shen, Dane Hoffman, Luis Becerra Dominguez, Charlotte Helena Rivas, Xiang Chen, Hai Wang, Yibin Kang, Zbigniew Gugala, Robert L Satcher, Xiang H-F Zhang May 2026

Unbiased Niche Labeling Maps Immune-Excluded Niche In Bone Metastasis, Tianhong Pan, Yi-Hsuan Wu, Yujiao Han, Jun Liu, Igor L Bado, Weijie Zhang, Ling Wu, Yang Gao, Xiaoxin Hao, Liqun Yu, Xuan Li, David G Edwards, Hilda L Chan, Sergio Aguirre, Michael Warren Dieffenbach, Elina Chen, Siyue Wang, Yichao Shen, Dane Hoffman, Luis Becerra Dominguez, Charlotte Helena Rivas, Xiang Chen, Hai Wang, Yibin Kang, Zbigniew Gugala, Robert L Satcher, Xiang H-F Zhang

Faculty, Staff and Students Publications

Metastatic cancer cell fate is shaped by the local microenvironment niches. To unbiasedly define the cellular and molecular features of metastatic niches, we developed sortase A-based microenvironment niche tagging (SAMENT), which selectively labels cells encountered by cancer cells during metastasis. Applying SAMENT across multiple cancer models and target organs revealed shared niche features, including macrophage enrichment and T cell depletion, alongside marked organ-specific phenotype heterogeneity in niche macrophages. In bone, metastatic niches are enriched for macrophages expressing estrogen receptor alpha (ERα) with active ERα signaling. Conditional deletion of Esr1 in macrophages significantly impaired bone colonization by enabling T cell infiltration. …


Icam1high Neutrophils Sculpt Tumor Evolution And Metastasis Through Symbiotic Adhesion And Reverse Migration, Fengshuo Liu, Yunfeng Ding, Yang Gao, Siyue Wang, Jun Liu, Hilda L Chan, Weiguo Wu, Yi-Hsuan Wu, Liqun Yu, Xiaoxin Hao, Xuan Li, David G Edwards, Cher Sha, Tobie D Lee, Nan Guan, Sergio Aguirre, Luis Becerra-Dominguez, Dane Hoffman, Xiang Chen, Charlotte Helena Rivas, Xiaoyuan G Yan, Igor L Bado, Weijie Zhang, Qian Zhu, Arun Sreekumar, Robert L Satcher, Xiang H-F Zhang May 2026

Icam1high Neutrophils Sculpt Tumor Evolution And Metastasis Through Symbiotic Adhesion And Reverse Migration, Fengshuo Liu, Yunfeng Ding, Yang Gao, Siyue Wang, Jun Liu, Hilda L Chan, Weiguo Wu, Yi-Hsuan Wu, Liqun Yu, Xiaoxin Hao, Xuan Li, David G Edwards, Cher Sha, Tobie D Lee, Nan Guan, Sergio Aguirre, Luis Becerra-Dominguez, Dane Hoffman, Xiang Chen, Charlotte Helena Rivas, Xiaoyuan G Yan, Igor L Bado, Weijie Zhang, Qian Zhu, Arun Sreekumar, Robert L Satcher, Xiang H-F Zhang

Faculty, Staff and Students Publications

Neutrophils are a prominent component of the tumor microenvironment that can have both pro- and anti-tumor functions. By analyzing neutrophils across different human cancers, we revealed an ICAM1high subset enriched in the tumor microenvironment, which were also observed in murine triple negative breast cancer (TNBC) models. ICAM1high neutrophils exhibited an enhanced capacity for cell-cell adhesion specifically with tumor cells retaining epithelial features, and this adhesion conferred mutual advantages to both cell types. In contrast, cancer cells with mesenchymal-like phenotypes were vulnerable to neutrophil-mediated cytotoxicity due to decreased cell adhesion and elastase resistance. These opposite effects drove tumor evolution toward a …


Applicability Of Diatom Indices And Phytoplankton Functional Groups To Assessment Of Water Quality In The Coastal Egyptian Mediterranean Estuary, Fatma A. Zaghloul, Soha H. Shabaka May 2026

Applicability Of Diatom Indices And Phytoplankton Functional Groups To Assessment Of Water Quality In The Coastal Egyptian Mediterranean Estuary, Fatma A. Zaghloul, Soha H. Shabaka

Blue Economy

This study provides the first application of diatom-based water quality and eutrophication assessments in Egypt, focusing on the El Mex Bay situated along the Mediterranean Coast of Egypt, providing a comprehensive evaluation of how diatom assemblages can serve as reliable bioindicators for ecological monitoring in this heavily impacted coastal system. It analyzes two distinct periods: monthly from 2003-2004 and seasonally from 2020-2021. Diatom community composition shifted significantly between the two decades. The earlier period hosted 109 diatom species, which declined to 69 species in the later period. Concurrently, overall abundance decreased from 1,071 x 10³ to 728 x 10³ cells/L. …


Seaweed-Derived Bioactives: A Promising Source Of Novel Therapeutics, Aida H. Shobier, Sahar W.M. Hassan, Safaa A. Abdel Ghani May 2026

Seaweed-Derived Bioactives: A Promising Source Of Novel Therapeutics, Aida H. Shobier, Sahar W.M. Hassan, Safaa A. Abdel Ghani

Blue Economy

The marine environment provides bioactive natural products with unique structures that are absent in terrestrial compounds. This review aims to provide a thorough overview of key studies on bioactives derived from seaweeds. It focuses on their potential to address common diseases such as microbial infections, diabetes, oxidative stress, inflammation, viral infections, cancer, immune disorders, and Alzheimer's disease as well as their potential use in drug delivery systems. The bioactive compounds found in seaweeds belong to various chemical classes, with the largest proportion being polysaccharides, lipids, proteins, phenolics, pigments, terpenoids, alkaloids, and sterols. These compounds possess significant pharmacological potential. …


From Double Absence To Double Presence: Video-Selfie As Empowerment In A Multicultural Italian Classroom, Maria Ranieri, Ilaria Bucciarelli, Giulia Cuozzo May 2026

From Double Absence To Double Presence: Video-Selfie As Empowerment In A Multicultural Italian Classroom, Maria Ranieri, Ilaria Bucciarelli, Giulia Cuozzo

Journal of Media Literacy Education Pre-Prints

This paper examines the video-selfie as a tool for empowerment in multicultural secondary school classrooms. We draw on data from the European ICME project, focusing on a vocational secondary school in Italy, where 17 of 18 first-year students – approximately half of whom had migration backgrounds – produced short videos presenting themselves through personally meaningful objects. Students then participated in a structured reflection activity after watching each other's videos in class. We combine three theoretical frameworks: critical media literacy, identity and self-representation studies, and Mezirow's transformative learning theory. Our argument is that the video selfie empowers in multiple ways: it …


The Applicability Of A Scale On Self-Regulated Writing Strategies In English For High School Students, Teresa Angelina Kaluge, Sisilia Setiawati Halimi May 2026

The Applicability Of A Scale On Self-Regulated Writing Strategies In English For High School Students, Teresa Angelina Kaluge, Sisilia Setiawati Halimi

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Writing appeared to be crucial in learning foreign languages. This study aimed at examining the applicability of a measure on self-regulated writing strategies in terms of its psychometric properties. The scale items were designed from theoretical foundations and previous relevant studies. Questionnaires were distributed online to high school students, collected and analyzed as many as 106. Correlation, confirmatory factor analyses, and calculating Cronbach’s alpha were carried out to make sure the applicability of the scale. The findings showed five main constructs to be applicable. They were self-initiating, planning, text-generating, revising, and acting on feedback.