Digital Commons Network^™

Regulation And Therapeutic Targeting Of Virus-Specific Resident Memory T Cells, Jordan Fredriksen Isaacs

Dartmouth College Ph.D Dissertations

CD8+ T cells are critical to the immune response to pathogens, as they kill infected cells and generate immunologic memory. Following infection, antigen-specific T cells expand approximately 10,000-fold and migrate to sites of inflammation in order to clear the pathogen. Once infection is resolved, a small pool of memory T cells persist in circulation and within tissues ready to respond rapidly upon re-exposure. Given the importance of CD8+ T cells, significant efforts have been made over the years to better understand how different memory T cell subsets are established, maintained, and regulated. The most recently identified subset, resident memory T …

Book Review: Resourcing The National Security Enterprise: Connecting The Ways And Means Of Us National Security, Christopher Sandrolini

Parameters Bookshelf – Online Book Reviews

Edited by: Susan Bryant and Mark Troutman

Reviewed by Christopher Sandrolini, Foreign Service officer and professor, US Army War College

Foreign Service officer and US Army War College professor Christopher Sandrolini calls this anthology, which contextualizes the defense budget within federal spending, a “well-organized and lucid practical introduction to working within the confines of a bureaucracy.” He highlights and distills Bryant and Troutman’s main arguments, noting, “[m]astering these rules [of bureaucracy] is essential to turn strategies and policies into funded, viable programs.” He also discusses the book’s explanation of how the Department of Defense balances the “four pillars” framework (force …

Adt Nurse: Impact On Nursing Satisfaction, Throughput And Practice, Elizabeth Mounir, Jen Sartin, Matthew Lemke, Sue Harvey

Nursing

Background: Nurses are faced with the complex needs both of their patients and the hospital system itself. There are increased levels of stress within the nursing profession, packed emergency departments along with a larger focus on quality care (Kurtzman et al., 2022). An admission, discharge, transfer (ADT) nurse is a resource that has quality, cost, and nursing satisfaction implications (Perry, 2017).

Purpose: The purpose of the ADT nurse pilot was to implement an innovative nursing role to see its impact on the hospital staff, patients, and the hospital itself.

Methods: The ADT Nurse was implemented within an urban, mid-sized hospital …

The Impact Of The Quadricep Angle On Female Athletes, Hannah Rae Grant

Honors Capstone Projects and Theses

No abstract provided.

Student Research Symposium Schedule 2024, Texas A&M University-San Antonio

Student Research Symposium 2024 (Archived)

No abstract provided.

Textbook Affordability Committee Minutes, April 19, 2024, Illinois State University, Textbook Affordability Committee

Textbook Affordability Committee

No abstract provided.

Quantifying Diagenesis Of Florida Fish Scales Using Ir Spectroscopy, Brian Manzanares, Ivett De La Rosa, Alanna L. Lecher, Erika L. Doctor

Student Publications and Presentations

Infrared spectroscopy (IR) is a powerful tool in archaeology to understand the chemical composition of artifacts. Bone digenesis is the chemical and physical process by which bones degrade over time. Archeologists discovered that archaeological bones from different excavation sites have different states of physical diagenesis, depending on site conditions. Methods are needed to quantify the chemical aspect bone digenesis. We are using fish scales, from South Inlet Park in Florida as a model to test IR spectroscopy as a new method to quantify bone digenesis. In this experiment, we used excavated fish scales and categorized them into three diagenetic categories: …

Postpartum Fall Prevention Is Key! Let's Take A Look And See How To Be Fall Free, Katherine Martinez, Elise Poelking, Bryn Adams, Yvonne Renick

Nursing

No abstract provided.

Less Is More: Exploring A Two-To-One Preceptorship Model, Megan Hanson, Nicole Guyer, Sheryl-Lyn Quijano

Nursing

Background/Significance: In a post pandemic state of nursing, experienced preceptors are in limited supply, and those that remain are at risk for burnout. A newly expanded unit hiring large volumes of new graduate nurses (NGNs) needed to redesign orientation to accommodate NGNs with resources available.

Purpose of Project or Study: Project aimed to utilize preceptors more efficiently without lengthening orientation, diminishing orientation experiences, or postponing hiring. Implemented a two orientee to one preceptor (2:1) pilot for two NGN cohorts.

Lit Review: Limited literature is available evaluating nursing preceptorships outside of traditional one-to-one approaches. Other healthcare disciplines demonstrated benefits utilizing a …

Prescribing The “Right Dose” Of Education For Practice Changes, Alisha Updike, Julie Dobbs, Jacqueline Dolatowski, Lillian Jensen, Megan Suszek

Nursing

The sky is falling! In effect, this was how subject matter experts in a multi-state organization responded to new or changing policies, procedures, or guidelines (PPGs), often regardless of a nursing-specific impact analysis. Minor PPG changes sometimes led to an over-the-top response such as full-blast marketing campaigns and required learning. Simultaneously, nurses often reported feeling uninformed of critical changes impacting care delivery, while also voicing education overload. The regional Nursing Education and Professional Development (NEPD) team sought a way to provide a consistent standard for determining and providing the right dose of education based on criticality. A review of the …

All Leader Rounding Approach To Improve Patient Experience, Jessica Yates, Wendy Lundeen-Nelson, Allison Klein

Nursing

The importance of patient experience has been heightened since the implementation of the Patient Protection and Affordable Care Act in 2010, which included Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) performance into the value-based payment program (CMS, n.d.). Essentially, this means hospitals must meet or exceed patient experience benchmarks to receive the highest payments for the services provided. In an effort to exceed these patient experience benchmarks, a southeastern Wisconsin hospital implemented an all leader rounding program in April 2023 with an aim to round on all patients at least once during their stay. This hospital was consistently …

Fruits And Vegetables: Catalase Inhibitors, Victoria Hendricks, Cassandra S. Korte, Erika L. Doctor

Student Publications and Presentations

Flavonoids are a class of chemicals that are found in plants, meaning they are commonly consumed within people’s diets. Flavonoids also act as inhibitors within the body. Inhibitors slow down or stop chemical reactions from taking place. In this case, the flavonoids react with the enzyme catalase to inhibit its activity. Catalase in the body is typically associated with the presence of an infection or inflammation. This leads to increased levels of hydrogen peroxide in the body, which reacts with the catalase. This study examines the flavonoids present in cherries and spinach to determine their effect on catalase activity. Flavonoids …

Can Psilocybin Be Used For The Treatment Of Major Depressive Disorder?, Suncharone Jolteus, Anaïsha Desravines, Sebastian Leslie, Khalique Ahmed

Student Publications and Presentations

Major Depressive Disorder (MDD), also known as clinical depression, is a serious problem in our society as an estimated 21 million American suffer for this clinical condition. A main strategy for the treatment of MDD involves the inhabitation of the reuptake of serotonin and/or noradrenaline. To correct this problem selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs) are commonly used for the treatment of MDD.

This traditional treatment approach has many side effects, which include gastrointestinal problems, insomnia, cognitive impairment, and activation and aggravation of psychosis, etc. Additionally, about 20% of patients do not respond to such treatments, …

What The Butt: Pressure Injury Reduction In Intensive Care, Noor Bontz, Michelle Emick, Matthew Lemke, Laura Reindl, Kristan Jesel

Nursing

No abstract provided.

Faculty Library News - April 2024, Rit Libraries

RIT Digital Archives

No abstract provided.

Student Library News - April 2024, Rit Libraries

RIT Digital Archives

No abstract provided.

English Language Learning At Tertiary Level In A Central Mexican Public University: A Case Study, Irasema Mora-Pablo, Edgar Emmanuell Garcia-Ponce

Higher Learning Research Communications

Objective: Our objective was to examine the perceptions regarding the teaching and learning of English of students in 16 undergraduate programs at a state public university in Mexico.

Method: In our qualitative case study, participating students responded to queries about their experiences learning English at the university, as well as their educational aspirations upon completion of their university studies.

Results: Despite their relevance to language immersion and competency, students struggle to combine prior experiences with current learning. Given Mexico’s English education system and past national initiatives, most participants say they still speak basic English. It is also clear that the …

Celestial Visitors, Opera Chapman

Printed Performance Programs (PDF Format)

No abstract provided.

Spring Commencement At Uab Will Be April 26-27, Shannon Thomason

Browse All News

No abstract provided.

Adapting Digital Masking For Improved Exoplanet Detection, Elise Seaward

Aerospace, Physics, and Space Science Student Publications

Our target object is HD15745, an F2V star with an extended scattered light disk. 27 Images were taken by the Hubble Space Telescope's (HST) Imaging Spectrograph (STIS) and its coronagraph, which helps to reveal faint structures while suppressing the star's glare. The images were captured using Angular Differential Imaging (ADI) by changing the roll angles of HST. Using Affinity Photo 2 software, the images were masked, and Python was used to perform Point Spread Function (PSF) subtraction and Principal Component (PCA) on the data. This analysis provides us with insight on the most important structures and features in the disk …

Implementation Of Python Based High Voltage Tests For Gem Detectors, John Paul Hernandez

Aerospace, Physics, and Space Science Student Publications

The Compact Muon Solenoid, CMS, and other detectors at LHC are in the process of being upgraded for the HL-LHC (High-Luminosity Large Hadron Collider) which will produce more than 5 times the particle interactions than of the current LHC. One upgrade to CMS is the introduction of new GEM detectors (Gaseous Electron Multiplier), GE2/1 and ME0 shown at right are new detectors to CMS and therefore must be tested thoroughly prior to being installed.

Trey Blaser, Composition In A Senior Recital, April 19, 2024 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Mindful Parenting And Harsh Parenting: The Indirect Role Of Maternal Stress, Heidi M. Sanders

Individual, Family, and Community Education ETDs

This study explored associations between maternal mindful parenting (i.e., mindful discipline, being in the moment with the child), maternal parental stress, and harsh parenting (i.e., physical and psychological harsh parenting) in early childhood. A sample of 172 mothers of young children in New Mexico completed questionnaires assessing perceived parental stress, use of harsh parenting, and mindful parenting. Results of the path model analysis demonstrated that being mindful in the moment with the child was directly, negatively associated with physical harsh parenting and also negatively associated with perceived stress. Mindful discipline was directly, negatively associated with both psychological aggression and perceived …

2023-2024 Performance Forum - April 19, 2024, Ana-Maria Uzunova, Gabrielle Malaniak, Ryan Barrett, Emin Huseynov, Patrick Hengstler, Nathan Clifford, Ryan Aguilar, Giah Bush, Elizaveta Goryunova, Amelia Dixon, Julian Rauh, Sheng Yuan Kuan

Performance Forum

No abstract provided.

Trial Competition Team | Closing Argument Competition, New York Law School

Student Organizations

April 19, 2024

Combating Trauma And The Immigrant Paradox In Schools, Emma Bergman

Honors Projects

Over time, research on immigrant populations has revealed a trend known as the immigrant paradox in which, the further generations get from the generation of immigration, the poorer their outcomes are in areas such as mental health, delinquency, substance abuse, and education. Though a definitive explanation for this trend has yet to be identified, prevailing theories include several social, familial, and community-based factors such as the impacts of bilingualism, parental expectations, biculturalism, co-ethnic peers, quality of schools, and community support. Little attention has been paid to individual factors such as mental health and trauma. The present study proposes the transgenerational …

Sexual Health Education Scope And Sequence, Sara Wadsworth

Honors Projects

Based on a significant amount of prior research, comprehensive sexuality education (CSE) has been identified to be the most effective method of teaching sexual health education (SHAPE America, 2021; World Health Organization, 2023). Comprehensive sexual health education improves healthy behaviors and outcomes, provides useful information, and is positively perceived by students (Gardner, 2015; Kirby, 2002; Robinson et al., 2022). However, the United States’ current sexual health education has not implemented this ideal method, which is shown through state laws, students’ experiences, underdeveloped skills and flawed understanding of concepts, and – most importantly – a lack of resources for teachers (Foley, …

The Relationship Of Psychology And Music, Thomas Pulling

Honors Projects

This paper discusses the relationship between psychology and music, examining some of the foundational research in the field, and looks at some of the historical context surrounding the psychological study of music and of music theory. The goal of this project is to use my experience as a performing musician and psychology student to emphasize the importance of furthering research into the psychology of music.

Therapeutic Strategies For Rb1-Deficient Cancers: Intersecting Gene Regulation And Targeted Therapy

Faculty, Staff and Student Publications

The retinoblastoma (RB) transcriptional corepressor 1 (RB1) is a critical tumor suppressor gene, governing diverse cellular processes implicated in cancer biology. Dysregulation or deletion in RB1 contributes to the development and progression of various cancers, making it a prime target for therapeutic intervention. RB1's canonical function in cell cycle control and DNA repair mechanisms underscores its significance in restraining aberrant cell growth and maintaining genomic stability. Understanding the complex interplay between RB1 and cellular pathways is beneficial to fully elucidate its tumor-suppressive role across different cancer types and for therapeutic development. As a result, investigating vulnerabilities arising from RB1 deletion-associated …

Mapping Of Alzheimer’S Disease Related Data Elements And The Nih Common Data Elements, The Alzheimer’S Disease Neuroimaging Initiative

Faculty, Staff and Student Publications

Background

Alzheimer’s Disease (AD) is a devastating disease that destroys memory and other cognitive functions. There has been an increasing research effort to prevent and treat AD. In the US, two major data sharing resources for AD research are the National Alzheimer’s Coordinating Center (NACC) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI); Additionally, the National Institutes of Health (NIH) Common Data Elements (CDE) Repository has been developed to facilitate data sharing and improve the interoperability among data sets in various disease research areas.

Method

To better understand how AD-related data elements in these resources are interoperable with each other, we …