Digital Commons Network^™

Body Mass-Normalized Handgrip Strength As A Better Indicator Of General Health Than Absolute Values In Middle-Aged Women, Ricardo M. Lima, Trezise, Sally Poppitt, Amanda Devine, Anthony J. Blazevich

Research outputs 2022 to 2026

Objectives: To examine the association between HGS and physical function, quality of life (QoL), and cardiometabolic risk markers in midlife women, and verify potential discrepancies between absolute and relative HGS on these relationships. Study design: This cross-sectional study enrolled 83 participants (50.7±5.3y) who completed handgrip (hydraulic dynamometer), knee extensor and plantar flexor (isokinetic dynamometry) strength tests, and body composition evaluations (DXA). A variety of physical function tests, QoL (SF-36) and cardiometabolic blood markers were also measured. Results: Participants below the cutoff for HGS/body mass (0.34) did not differ in height but were significantly (P<0.01) heavier (80.8±12.8 vs. 68.6±11.4 kg), had higher BMI (30.0±4.2 vs. 25.4±4.0 kg/m²) and body fat (39.9±4.4 …

Aviation Accident Investigation Analysis Methodologies Used By 12 Government Safety Investigation Authorities, Kym Bills, Leesa Costello, Marcus Cattani

Research outputs 2022 to 2026

Introduction: Leading government Safety Investigation Authorities (SIAs) that investigate major aviation accidents are members of the International Transportation Safety Association (ITSA). Investigation analysis methodology details are rarely included on SIA websites, in final accident reports, shared with peers, or specified by the International Civil Aviation Organization (ICAO). Some ‘New View’ safety researchers assume SIAs don't use systemic methodologies and that accident investigation has little value. Because of the sensitivity of SIA work and need to prioritize safety value from available investigation funding, there has been little academic research on choice and use of investigation analysis methodologies to address these issues …

Higher Sodium Intake Is Associated With Episodic Memory Decline In Cognitively Unimpaired Older Males: A 6-Year Longitudinal Study, Francisca Chuwa, Stephanie R. Rainey-Smith, Hilal Salim Said Al Shamsi, Hamid Sohrabi, Kevin Taddei, Colin L. Masters, Ralph N. Martins, Samantha L. Gardener

Research outputs 2022 to 2026

Recent evidence has suggested an association between high sodium intake and development of cognitive impairment. However, while animal studies demonstrate consistent relationships between sodium intake and cognitive impairment, this relationship remains less clear in humans. Our aim was to investigate the relationship between self-reported baseline sodium intake and cognitive decline over 72 months. Cognitively unimpaired participants (n = 1208) from the Australian Imaging, Biomarkers and Lifestyle study were included (70.87 years of age; 41 % male). Participants completed a food frequency questionnaire to quantify sodium intake and underwent comprehensive neuropsychological assessment at baseline and four additional timepoints, 18 months apart. …

The Future Of Epilepsy Care In The United Kingdom: A Roadmap For Technology-Enabled Transformation, Rohit Shankar, John Terry

Peninsula Medical School

Epilepsy is recognized to be a significant cause of premature mortality, socio-economic distress and poor quality of life in economically developed countries. Despite clear clinical guidelines, epilepsy care is marked by delayed diagnosis, fragmented management, high emergency admission rates, and pronounced health inequalities affecting rural populations, ethnic minority groups, and people with intellectual disabilities. Diagnostic pathways remain inefficient, with prolonged waits for electroencephalography (EEG), low sensitivity of routine investigations, and repeated inconclusive testing. Long-term management continues to depend on infrequent hospital visits and unreliable patient recall, contributing to suboptimal seizure control, avoidable morbidity, and preventable mortality. In the United Kingdom, …

Toward A Synthetic Theory Of Tolerance For Carnivores: Learning From A Half-Century Of Research On Attitudes Toward Wolves, Jeremy T. Bruskotter, John A. Vucetich, Lisa Naughton-Treves, José Vicente López-Bao, Benjamin Ghasemi, Nicole D. Sintov, Tara L. Teel, Neil H. Carter, L. Mark Elbroch, Adrian Treves

Michigan Tech Publications

Human intolerance is a critical factor limiting both the distributions and populations of large carnivores. Using gray wolves as a case study, we synthesize a half-century of scholarship with the aims of clarifying the conceptual foundations of “tolerance” and integrating insights from across the social sciences. Specifically, we review longitudinal studies of attitudes toward wolves and show how trends vary across the populations examined. We then identify and discuss three complementary theories that help explain variation in tolerance across individuals, social groups, and societies: (1) Risk–benefit theories illuminate how perceptions of risks, benefits, and controllability shape individuals’ tolerance of carnivores; …

S-[2-(Hydroxyamino)-2-Oxoethyl]-O-Octyl-Dithiocarbonate Ester (Ehaox): Performance And Adsorption Mechanism, Yue Zhou, Jiaxiang Li, Hongli Fan, Zhilong Li, Yuesheng Gao, Tian Lin, Haiyan Tang, Tingting Wang, Wei Sun

Michigan Tech Publications

This study explores the interfacial interactions between a novel collector, S-[2-(hydroxyamino)-2-oxoethyl]-O-octyl-dithiocarbonate ester (EHAOX), and bastnaesite mineral surfaces during selective flotation. Compared to conventional octylhydroxamic acid (OHA), EHAOX demonstrated superior recovery, achieving an over 40% absolute increase in recovery compared to octylhydroxamic acid (OHA) at the same collector concentration (1 × 10⁻⁵ mol/L) and pH 8.0, and selectivity for bastnaesite, attributed to its optimized hydrophobicity (supported by CLogP calculations). Mechanistic studies via zeta potential, UV/vis spectroscopy, and FTIR revealed the formation of a complex composite via chemisorption between EHAOX and Ce³⁺ sites on the bastnaesite surface, with coordination occurring …

Influences On Growth And Survival Of Seedlings Planted In Black Ash Stands Of Northern Michigan And Wisconsin, Seth W. Davenport, Dustin R. Bronson, Kathryn L. Hofmeister, Randall K. Kolka, Grady J. Boyle, Fengjing Liu

Michigan Tech Publications

The invasive emerald ash borer (Agrilus planipennis) is a threat to all North American ash (genus Fraxinus) trees, but wetland ecosystems dominated by black ash (F. nigra) are of particular concern to land managers. The rapid and extensive death of black ash on the landscape causes unprecedented ecological and hydrological impacts to cascade through the ecosystem. A strategy to combat such impacts and maintain these wetlands as forested is to underplant these stands with seedlings of alternative species that are capable of maturing into canopy trees. This study planted seedlings of seven non-ash tree species in black ash wetlands across …

Satellite-Based Forest Structure Metrics As A Predictive Tool For Biodiversity In Hyperdiverse Tropical Forests: A Test Of The Habitat Heterogeneity Hypothesis In The Tropics, David Luther, Marconi Campos-Cerqueira, Aline Medeiros, Aidan Mccarthy, Emilia Roberts, Xiaoxuan Li, Paulo Bobrowiec, Jared Wolfe, Gabriel Augusto Leite, Tomaz Nascimento De Melo, José W. Ribeiro, Thiago Bicudo, Konrad Wessels

Michigan Tech Publications

Tropical forests hold the most species yet face the greatest threats and knowledge gaps. To improve tropical biodiversity knowledge we combined satellite-based LiDAR with in situ bird, mammal, and acoustic soundscape data, via camera and audio recorders, at the Biological Dynamics of Forest Fragments Project in the Amazon rainforest and tested the habitat heterogeneity-diversity hypothesis as a predictor of alpha diversity in tropical forests. GEDI spaceborne LiDAR was used to assess the predictive power of vertical forest structure on acoustic diversity and species diversity in lowland tropical forests. In 4 months, we detected 201 bird and 35 mammal species representing …

Neuromarketing Research Through The Years: A Bibliometric Review Of Technological Advancements And Multisensory Studies, Md Abu Issa Gazi, Md Mustaqim Roshid, Abdul Waaje, Md Bony Yeamin, Rejaul Karim, Mohammad Bin Amin, Abdul Rahman Bin S. Senathirajah, Judit Oláh

Michigan Tech Publications

The current study examines the changes in neuromarketing studies between 2015 and 2024, particularly in the context of new technologies incorporating multisensory interventions. It attempts to identify significant trends, influential texts, and topical developments that shape the field. A bibliometric method was employed to review 307 publications within the study's framework, using the Scopus database. Bookmarked by methods such as keyword co-occurrence, co-citation, cluster analysis, performance analysis, and science mapping techniques, these are implemented using programs like VOSviewer or Biblioshiny. The results show a significant increase in the number of neuromarketing studies, with notable works from Italy, Spain, and the …

Constraints On Axion-Like Particles From Ultra-High-Energy Observations Of M87 With The Hawc Observatory, R. Alfaro, C. Alvarez, A. Andrés, E. Anita-Rangel, M. Araya, J. C. Arteaga-Velázquez, N. Ghosh, M. Najafi, Et Al.

Michigan Tech Publications

In this work, we perform an indirect search for axion-like particles (ALPs) through their hypothesized mixing with photons in the presence of magnetic fields. ALPs are a well-motivated dark-matter candidate class, and the photon-ALP conversion mechanism provides a unique channel to constrain their mass and coupling constant using very-high-energy gamma-ray observations. The photon-ALP mixing could alter the observed gamma-ray spectrum from extragalactic sources by effectively reducing the apparent attenuation due to extragalactic-background-light absorption. We analyze 7.5 years of data from the High Altitude Water Cherenkov (HAWC) Observatory, targeting the nearby radio galaxy M87. This source is located within the Virgo …

When Robots Read Westlaw: Linking Inputs And Outputs In Generative Ai Fair Use Analysis, Aaron Lam

Vanderbilt Journal of Entertainment & Technology Law

Generative artificial intelligence has revealed a novel tension in copyright law: a two-stage act (input and output) of copying that traditional fair-use doctrine never squarely anticipated. In the input stage, vast swaths of copyrighted expression are reproduced and ingested to train large language models. In the output stage, those models generate works that may substitute for or dilute the market of the originals. Courts now face both stages. Their rulings diverge when they consider training and outputs together. In Bartz v. Anthropic PBC and Kadrey v. Meta Platforms, Inc., the courts characterized training uses as “highly transformative,” yet reached opposite …

When The Purse Strings Paint The Picture: Executive Overreach And Censorship In Federal Arts Funding, Megan Brown

Vanderbilt Journal of Entertainment & Technology Law

For decades, the National Endowment for the Arts (NEA) has been tasked with distributing federal funds to museums, galleries, and artists to promote visual artwork for its meritorious qualities and cultural impact. However, the NEA’s role as both a patron and regulator of visual artwork has placed it at the center of a balancing act—funding creative expression that often displays controversial themes, while facing political pressure to define what is a worthy investment of taxpayer dollars. This conversation continues in light of recent executive orders: “Ending Illegal Discrimination and Restoring Merit-Based Opportunity” and “Ending Radical and Wasteful Government DEI Programs …

Ambulatory Blood Pressure Monitoring Phenotypes And Circadian Blood Pressure Patterns Among Adults Referred For Diagnostic Evaluation At Aga Khan University Hospital, Nairobi, Kenya: A Retrospective Cross-Sectional Study, Nadeem Kassam, Mzee Ngunga, James Orwa, Alisa Bhojani, Mohamed Varwani, Swaffiya Salim, Yvonne Oketch, Salim Surani, Anthony Ochola, Barbara Karau, Jeilan Mohamed, Etienne Amendezo

Internal Medicine, East Africa

Introduction: hypertension represents the primary modifiable risk factor for cardiovascular disease and poses a public health challenge in sub-Saharan regions, with Kenya experiencing particularly low detection and control rates. Traditional office-based blood pressure measurements often fail to detect key phenotypes, such as white-coat and masked hypertension. Ambulatory Blood Pressure Monitoring (ABPM) offers a comprehensive 24-hour profile that excludes white-coat hypertension and allows for the evaluation of circadian patterns, including nocturnal hypertension and non-dipping status, both of which are recognized as high-risk phenotypes strongly linked to adverse cardiovascular events. This study evaluated ABPM data from Aga Khan University Hospital, Nairobi …

Protective Potential Of Minimally Processed, Plant-Derived Foods Against Steatotic Liver Disease In Early Adulthood, Yasmina Tashkent, Jocelyn M. Choo, Steven L. Taylor, Therese A. O'Sullivan, Dujinthan Jayabalan, Sophie J. Miller, Richard Woodman, Luis Calzadilla-Bertot, Oyekoya T. Ayonrinde, Lawrence J. Beilin, Trevor A. Mori, John K. Olynyk, Alan J. Wigg, Kate R. Muller, Leon A. Adams, Geraint B. Rogers

Research outputs 2022 to 2026

Background & aims: The incidence of steatotic liver disease (SLD) among younger adults is increasing globally. While poor diet is a recognised risk factor, the impact of specific dietary components is unclear. We investigated associations between dietary patterns and SLD markers in younger adults. Methods: Analysis involved 887 members of the Raine Study Generation 2 cohort, assessed at age 27. SLD was defined using a validated MRI volumetric liver fat fraction equation. Dietary intake, assessed by food frequency questionnaires, was summarised using a modified Overall Diet Score (ODS) that classified foods as “healthy” or “unhealthy.” Associations between diet and SLD …

Being Reflexive About Reflexivity: The Ethical Imperative Of Reflexive Practice When Engaging In Sensitive And Contentious Research, Giselle Woodley, See, Sian Tomkinson, Stephanie Milford

Research outputs 2022 to 2026

Research topics involving sex, sexuality or sexual content online including pornography, are often considered sensitive or contentious. These topics can evoke strong attitudes, values, beliefs, biases, and potential prejudices from researchers themselves. As such, it is ethically imperative to identify and critically examine one's own perspectives in relation to the research on such topics to ensure transparency, acknowledge the researcher's positionality, and prioritise participant perspectives. Reflexivity offers a valuable way to sustain critical reflection and engage with one's own position and assumptions towards the topic in question. This paper offer a vulnerable exploration and reflection on the reflexive process within …

Blue Carbon Stocks, Accumulation Rates And Knowledge Gaps In Africa, Janine B. Adams, Pattrick, Pere Masqué, Dennis Adotey, Elsheikh Bashir Ali, Abdelgadir Bashir Mohamed Awatif, Mohamed Fathi Ben Hamouda, Moncef Benmansour, Joseph F. Charles, Jerome Harlay, Lucienne Human, Linet Kiteresi Imbayi, Rashid Omari Ismail, Anesu Machite, Nezha Mejjad, Athi N. Mfikili, Ndanu Mumo, Maurice Ndeye, Wilfried Essowè Panassa, Issa Sakho, Suleiman Suleiman, Vanessa Hatje

Research outputs 2022 to 2026

Blue carbon ecosystems (BCEs), including mangroves, salt marshes, and seagrasses, play a critical role in climate mitigation due to their high carbon sequestration capacity. Despite Africa's extensive and diverse coastal ecosystems, continent-wide assessments of blue carbon stocks and accumulation rates remain scarce. Here, we synthesized blue carbon data from 87 publications (January 1993 - March 2026) to evaluate the current state of knowledge and regional variability. Our analysis reveals marked regional heterogeneity in sediment organic carbon (SOC) stocks across Africa, reflecting both ecological variability and methodological differences among studies. Normalised to a sediment depth of 1 m, median SOC stocks …

Centring Girls In Water Justice Research And Social Movements, Cecilia Chitukula, Wrigley, Julie Nyanjom, Naomi Joy Godden

Research outputs 2022 to 2026

Scholars and activists focused on water justice in the Global South are increasingly embracing collaborative methods. These methods include community-centred research, public engagement in water management, and participatory interventions aimed at addressing the crisis of fresh and clean water access in both urban and rural localities. This represents a shift from state-led water management that is top-down, technocentric, and privatised, towards just and equitable water solutions which are informed by the needs of community members. In patriarchal societies of the Global South, girls are disproportionately affected by the water crisis, as they are tasked with water searching and fetching responsibilities …

Maternal Prenatal Anxiety And Risk Of Preterm Birth And Low Birthweight: Evidence From A Cumulative Meta-Analysis With Stability Thresholds, Bereket Duko, Desta, Biniyam Sahiledengle, Yohannes Tekalegn Efa, Tenaw Tiruye, Lisa Whitehead, Gavin Pereira, Amanuel Tesfay Gebremedhin

Research outputs 2022 to 2026

Background: We conducted cumulative meta-analyses to quantify the degree to which maternal prenatal anxiety impacts preterm birth (PTB) and low birthweight (LBW), and to identify when findings reached stability, enabling confident recommendations for early interventions. Methods: Following PRISMA guidelines, we systematically searched PubMed/MEDLINE, PsycINFO, Scopus, EMBASE, CINAHL (EBSCO), ProQuest, and the Cochrane Library from database inception to May 7, 2025. The methodological quality of included studies was assessed using the Newcastle–Ottawa Scale. Inverse variance weighted random-effects cumulative meta-analysis was performed to pool adjusted odds ratios (AORs) with sequential inclusion of newly published studies. Stability thresholds were computed to assess sufficiency …

Precision Nutrition In Breast Cancer: Towards Patient- And Tumour-Informed Dietary Strategies, Cristina Crespo-García, R. Taaffe, Carolyn Peddle-Mcintyre, Emily Jeffery, John P. Campbell, Robert Thomas, Daniel A. Galvao, Robert U. Newton

Research outputs 2022 to 2026

Dietary strategies are increasingly recognized as important modulators of breast cancer outcomes, acting through effects on metabolic regulation, weight management, hormone signalling, immune function, and the gut microbiome. However, breast cancer heterogeneity and inter-individual variability mean that generic dietary guidelines may not fully capture patient needs. Precision nutrition offers the opportunity to align dietary interventions with tumour subtype, treatment context, and host biology, potentially enhancing therapeutic response and survivorship in patients diagnosed with breast cancer. In this narrative review, we summarize evidence on dietary patterns and prognosis, and explore how targeted interventions, including fasting regimens, ketogenic diets, and caloric restriction, …

Shape-Based Profiling Of Cortical Bone Mineral Density In Growing Children: A Proof-Of-Concept Pqct Study, Anna Maria Markarian, R. Taaffe, Daniel Galvão, Jodie Cochrane Wilkie, Carolyn J. Peddle-Mcintyre, Daniel J. Schiferl, Robert U. Newton

Research outputs 2022 to 2026

Background: Understanding how bones adapt during growth is essential for promoting lifelong skeletal health. Peripheral quantitative computed tomography (pQCT) is a widely used imaging technique for assessing volumetric bone mineral density (vBMD) in pediatric populations; however, conventional methods may obscure subtle cortical adaptations. The primary aim of this study was to evaluate the feasibility of shape-based cortical vBMD profiling, with an exploratory objective of assessing its sensitivity to inter-individual variation in lean mass index (LMI). Methods: Eighteen children (6–12 years) underwent pQCT scanning at the 38% and 66% tibial sites (distal and proximal diaphysis). Cortical vBMD was quantified across three …

A Qualitative Exploration Of Unanticipated Effects Experienced By People With Chronic Obstructive Pulmonary Disease Who Participated In Interventions Designed To Reduce Sedentary Behaviour, Fiona Coll, Vinicius Cavalheri, Daniel F. Gucciardi, Kylie Hill

Research outputs 2022 to 2026

Introduction: This study explored the lived experiences of people with chronic obstructive pulmonary disease (COPD) who participated in interventions designed to reduce the accumulation of sedentary behaviour in prolonged uninterrupted bouts. Methods: Ten participants with stable COPD participated in a multi-component intervention that spanned over 9 months and was designed to address the intervention message ‘If you have been sitting or resting continuously for 30 min, stand up and move’. Interventions comprised participation in an 8-week programme of supervised exercise training coupled with behaviour change techniques. Throughout the intervention period the person delivering the intervention kept detailed notes of their …

Dietary Vitamin K Intakes, Chronic Obstructive Pulmonary Disease, Adult Asthma, And Lung Function: A Prospective Cohort Study In The Uk Biobank, Chengfeng Li, Pratik Pokharel, Marc Sim, Kevin Murray, Catherine P. Bondonno, Benjamin H. Parmenter, Liezhou Zhong, Montana Dupuy, Howraman Meteran, Jette Jakobsen, Allan Linneberg, Tilman Kühn, Aedín Cassidy, Nicola P. Bondonno

Research outputs 2022 to 2026

Background: Vitamin K–dependent proteins are important for maintaining lung structure and function, yet few studies have examined dietary vitamin K intake in relation to chronic respiratory disease. Objectives: This study aimed to investigate the associations between dietary intakes of vitamin K1 and vitamin K2 and the incidence of chronic obstructive pulmonary disease (COPD), asthma, and lung function. Methods: We analyzed data from 179,062 UK Biobank participants without COPD or asthma. Associations between dietary vitamin K1 and K2 intakes, estimated using the Oxford WebQ 24-h recall, and incident COPD and asthma, identified through hospital, death, and primary care records, were examined …

Factors Impacting Western Australian Midwives' Intention To Stay: A Mixed Methods Study, Christine Atkinson, Dianne Bloxsome, Zoe Bradfield, Kate Buchanan, Sarah Dawson, Frances Finch, Sadie Geraghty, Sara Bayes

Research outputs 2022 to 2026

Problem Midwifery workforce sustainability remains a critical concern for maternity services. Existing literature predominantly focuses on burnout and attrition, offering limited insight into what influences midwives’ decisions to remain within specific workplaces. Background Midwives consistently report strong professional commitment alongside growing workforce instability. National data indicate that uncertainty about current roles does not necessarily reflect disengagement from the profession. Understanding workplace-level influences on retention is therefore essential for targeted workforce strategy. Aim To examine how workplace stress and satisfaction with the practice environment are associated with Western Australian midwives’ intention to stay in their current job and in the profession. …

Holistic Strategy For Sustainable Supply Chains: Integrating The Purchasing Portfolio Matrix, Supplier Relationship Management, And Life Cycle Assessment, Farida Pulansari, Dean Tirkaamiana, Aulia Dita Ananda Lestari, Fadillah Kurniasari, Indhira Prameswari Susanto, Ferry Jie

Research outputs 2022 to 2026

This study proposes a holistic strategy for sustainable supplier management by integrating the Purchasing Portfolio Matrix (PPM), Supplier Positioning Matrix (SPM), and Life Cycle Assessment (LCA) within the Indonesian furniture industry. The study aims to enhance supplier segmentation and decision-making by incorporating economic, relational, and environmental dimensions into a unified framework. A case study approach is employed using the Best–Worst Method (BWM) to evaluate 74 suppliers, followed by portfolio analysis and environmental impact assessment. The results indicate that the majority of suppliers are concentrated in low-risk but high-profit categories, highlighting their strategic importance in the supply chain. The LCA results …

Multi-Sensory Information And Simulator Immersion: Impact On Decision-Making Performance, Presence, And Cognitive Load, Zachariah G. Hoyne, Khaya Morris-Binelli, Sean Müller, Benjamin Piggott, Paola Chivers, Evan Dekker

Research outputs 2022 to 2026

Immersive technologies such as 360-degree video virtual reality (360VR) provide unique opportunities to simulate representative environments to investigate decision-making in a safe and cost-effective manner. Inclusion of multi-sensory visual, contextual, and auditory information is important to enhance simulator psychological fidelity. Yet, the influence of increased sensory information on decision-making, presence, and cognitive load in 360VR compared to less immersive two-dimensional video simulators is unknown. This study investigated multi-sensory information, presence, and cognitive load across immersion conditions (360VR and two-dimensional video) in an exemplar sport-specific decision-making task. Fifteen higher-skilled and 15 lesser-skilled Australian Rules Football players completed a decision-making task which …

Occupational Therapy Intervention For Children With Developmental Coordination Disorder: A Survey Of Occupational Therapists In Australia, Jacqui Hunt, Jill G. Zwicker, Annette Raynor, Erin Godecke

Research outputs 2022 to 2026

Introduction: Developmental coordination disorder (DCD), a common neurodevelopmental condition, is associated with persistent motor and psychosocial difficulties impacting participation and quality of life. International guidelines recommend activity-/participation-focused, task-specific interventions; however, little is known about how Australian occupational therapists translate these recommendations into clinical practice. This study aimed to describe current Australian occupational therapy intervention for children with (or suspected to have) DCD and identify factors that shape occupational therapists' intervention choices. Methods: A cross-sectional online survey was distributed to Australian occupational therapists via professional organisations/social media September–October 2020. Eligible participants were registered occupational therapists with ≥15% children in their caseload. …

The Interplay Between Osteosarcopenia And Intrinsic Capacity: Insights And Associations With All-Cause Mortality In The Toledo Study For Healthy Aging, Ivan Baltasar-Fernandez, Pedro L. Valenzuela, Irene Rodríguez-Gómez, Fabio Quiñonez-Bareiro, Luis M. Alegre, Konstantinos Prokopidis, Leocadio Rodriguez-Mañas, Ignacio Ara, Oscar Rosas-Carrasco, Lana J. Williams, Robinson Ramirez-Vélez, Julie A. Pasco, Guy Hajj-Boutros, Raman Agnihotram, Marc Sim, Wayne Lok Ok Choo, Mahdi Imani, Ana M. Ayala-Copete, Julia Chabot, Miguel G. Borda, Nailton J. Neto, Claire Godard-Sebillotte, Howard Bergman, Anna Andrianova, Hidenori Arai, Pierrette Gaudreau

Research outputs 2022 to 2026

Background: Osteosarcopenia—the coexistence of osteopenia/osteoporosis and sarcopenia—is associated with numerous adverse health outcomes, but its association with intrinsic capacity (IC) remains unknown. We aimed to explore the associations of osteosarcopenia with IC and all-cause mortality in older adults. Methods: We conducted a cross-sectional analysis of IC and a prospective analysis of all-cause mortality in 1142 participants from the Toledo Study for Healthy Aging (75.1 ± 6.0 years, 53.1% women). Participants were classified as having no musculoskeletal disorders, osteopenia/osteoporosis, sarcopenia, or osteosarcopenia (DXA- and EWGSOP2-based criteria). IC was operationalized as a composite score integrating locomotion, cognition, psychological, vitality, and sensory domains. …

Calcium Signaling And Postsynaptic Density Dynamics: The Roles Of Calmodulin In Synaptic Protein Regulation, Keyaa Dilip Shah, Yonghong Zhang

School of Integrative Biological & Chemical Sciences Faculty Publications

Calcium signaling in neuronal cells is the principal mechanism underlying learning and synaptic plasticity, whereas the postsynaptic density (PSD) is an important center where calcium-dependent processes are organized and regulated. This review explores the roles of calmodulin (CaM) in facilitating calcium-dependent modulation of the activities of synaptic proteins in the PSD. We focus on the molecular processes through which CaM interacts with calcium signals to regulate the function, localization, and interactions of central synaptic proteins, including calcium/calmodulin-dependent protein kinase II (CaMKII), membrane-associated guanylate kinases (MAGUKs), and N-methyl-D-aspartate (NMDA) receptors. We aim to summarize recent advances in structural, biochemical, and imaging …

Advanced Mathematical Modeling And Data-Driven Techniques For The Diagnosis Of Diabetes Using Continuous Glucose Monitoring (Cgm) Data, Farah Morsi

Theses

Diabetes mellitus is a major and growing health challenge, particularly in the Middle East and North Africa (MENA) region. Continuous Glucose Monitoring (CGM) provides high-resolution time-series data that capture detailed glucose fluctuations over time. However, conventional CGM summary measures, such as mean glucose, standard deviation, and time-in-range, may not fully describe the nonlinear temporal structure of glucose dynamics.

This thesis investigates nonlinear dynamical approaches for analyzing CGM time series, with a focus on recurrence-based analysis and ordinal-network analysis. Recurrence-based methods, including recurrence quantification analysis (RQA), are used to characterize geometric and temporal patterns in reconstructed phase space, while ordinal networks …

استخدام تقنيات الذكاء الاصطناعي في إجراءات الاستدلال والتحقيق "دراسة مقارنة", حمد مصبح اليليلي

Theses

The Use of Artificial Intelligence Techniques in Reasoning and Investigation Procedures: Comparative Study

This research aims to analyze the role of artificial intelligence (AI) technologies in the stages of criminal investigation and inquiry through an applied analytical study. It focuses on the use of these technologies to support law enforcement and investigators with advanced scientific methods, particularly in analyzing digital evidence and accurately linking it to suspects. The study also explores the future development of these systems through their integration with AI technologies to enhance the efficiency of criminal investigation.

The United Arab Emirates has consistently been keen to develop …