Digital Commons Network^™

Characterization Of The Role Of Tobacco Deacetylase Enzyme Sip-428 In Mediating Environmental Stress, Zahra Barati

Electronic Theses and Dissertations

Abiotic stress poses a significant threat to crop productivity and food security. In this study, we focused on understanding the role of SIP-428, a SABP2-interacting protein, in mediating plant responses to environmental stresses. Transgenic tobacco plants overexpressing SIP-428 were subjected to salinity and drought stress. The overexpression of SIP-428 led to diminished growth under both stress conditions, indicating a negative impact on stress tolerance. Specifically, SIP-428 overexpression resulted in a reduction in catalase activity, while peroxidase activity remained unaffected. These findings suggest that SIP-428 plays a negative regulatory role on the catalase activity during abiotic stress, which may contribute to …

Internship Experiences For Aspiring Educational Leaders: Student Understanding And Effectiveness, Adam Douglas

Electronic Theses and Dissertations

The purpose of this study was to investigate East Tennessee State University alumni's perceptions of the effectiveness of internship experiences as students learned the PSEL and TILS standards and the role of mentor support as they prepared for principalship. The participants obtained their administrative license and worked currently with an administrative license that is current in the state they reside. This research focused on the perception of the PESL and TILS standards, the effectiveness of the 540-hour internship experience, and the value of the site based and university mentor as the participants completed their activities in multiple settings.

Findings supported …

No Tolerance For Zero Tolerance: Teacher Perceptions Of Restorative Practices, Meghann Ramsey

Electronic Theses and Dissertations

The original design of zero-tolerance policies was meant to support school safety through an anti-drug and violence campaign but in the years following their implementation, school districts have employed them repeatedly without merit. Exclusionary practices have become controversial, leading to high rates of recidivism, imbalanced implementation toward minority groups, and the loss of learning while suspended or expelled. Just as effective educators respond and intervene to instructional practices that are not proving successful, an overhaul of disciplinary practices was necessary for academic and emotional health. Restorative practices have emerged in recent years as an alternative process to the antiquated system …

The Beast In The Beauty: An Analysis Of Cultural Gender Biases And Stereotypes In The Classic Fairy Tale “Beauty And The Beast” And Implications In Modern Retellings, Lauren Lefler

Electronic Theses and Dissertations

This thesis looks at the fairy tale Beauty and the Beast to examine the way that this tale has been used throughout history to address the concerns of young women, as well as reinforce the culturally accepted gender roles of the time of their publication. The first chapter defines the fairy tale genre and features some of the most common criticism on the genre, it will then define and offer critical perspectives on the monster bridegroom motif which Beauty and the Beast is a part of. The second chapter will look at the first two publications of the text, the …

An Exploratory Study Of The Southern Subculture Of Honor In East Tennessee, Rachel Cohen

Electronic Theses and Dissertations

The culture of honor theory proposed by Nisbett and Cohen (1996) addresses the historically higher rates of violent crime in the Southern United States, as well as the disparities that can be observed in the laws, beliefs, and social expectations between the South and other regions. Previous research has reported significant differences between the beliefs of acceptable violence among Southerners compared to non-Southerners; however, no research has been conducted comparing different demographic groups of Southerners. The current study sought to evaluate whether there were observable differences between various demographic attributes such as gender, race, age, educational attainment, political affiliation, prior …

The Neoliberal Noirs Of Gary Indiana, Carson Morgan

Electronic Theses and Dissertations

This thesis is concerned with the two AIDS-era novels of Gary Indiana, a long-neglected yet essential literary figure who, as the critic Christian Lorentzen has argued, “connects the twentieth and twenty-first centuries in ways readers and critics are only beginning to apprehend” (xii). Beginning chronologically with a study of Indiana’s first two novels, Horse Crazy (1989) and Gone Tomorrow (1993), this thesis attempts to realize Lorentzen’s call to action, attending particularly to the ways in which Indiana’s novels write the neoliberal subject. More than exploring life under the AIDS crisis and embodying a radical queer approach to narrative, I contend, …

Changes In Young Adults’ Perspective On Ageism After Participating In A Virtual Nutrition Education Program With Older Adults, Julianne Hensley

Electronic Theses and Dissertations

The growing older adult population has led to increased ageist tendencies among younger generations. Previous research suggests that ageism is associated with cognitive and physical decline among older adults. This mixed-methods research project examined changes in ageist perceptions among graduate student facilitators and undergraduate nutrition ambassadors after participating in a training that included information about healthy aging, addressing ageism, and communicating with older adults. Results from a secondary data analysis of pre-test/post-test data and thematic analysis of semi-structured interviews with facilitators of Socially Nutritious, a virtual nutrition education program for older adults, indicate that ageist perceptions decreased after the …

The Local History Section Of Baguio City Public Library, Joana Colansong

Library Philosophy and Practice (e-journal)

JOANA MELCHOR COLANSONG, May 2024, The Local History Section of Baguio City Public Library. Benguet State University, La Trinidad, Benguet.

Adviser: Grace Dangawen Quijano, Ph. D.

The study focused on evaluating the present status of the Local History section within the Baguio City Public Library. It aimed to explore the frequency of utilization, purposes for usage, user satisfaction with the collections, services, and facilities, the importance of the section’s materials, and the preferred strategies for improving the Local History section at the Baguio City Public Library.

A survey questionnaire was utilized to gather data from individuals who utilized the …

Retinal Dystrophies Associated With Peripherin-2: Genetic Spectrum And Novel Clinical Observations In 241 Patients, Rachael C. Heath Jeffery, Jennifer A. Thompson, Johnny Lo, Enid S. Chelva, Sean Armstrong, Jose S. Pulido, Rebecca Procopio, Andrea L. Vincent, Lorenzo Bianco, Maurizio Battaglia Parodi, Lucia Ziccardi, Giulio Antonelli, Lucilla Barbano, João P. Marques, Sara Geada, Ana L. Carvalho, Wei C. Tang, Choi M. Chan, Camiel J. F. Boon, Jonathan Hensman, Ta-Ching Chen, Chien-Yu Lin, Pei-Lung Chen, Ajoy Vincent, Anupreet Tumber, Elise Heon, John R. Grigg, Robyn V. Jamieson, Elisa E. Cornish, Benjamin M. Nash, Shyamanga Borooah, Lauren N. Ayton, Alexis Ceecee Britten-Jones, Thomas L. Edwards, Jonathan B. Ruddle, Abhishek Sharma, Rowan G. Porter, Tina M. Lamey, Terri L. Mclaren, Samuel Mclenachan, Danial Roshandel, Fred K. Chen

Wills Eye Hospital Papers

PURPOSE: To describe the clinical, electrophysiological and genetic spectrum of inherited retinal diseases associated with variants in the PRPH2 gene.

METHODS: A total of 241 patients from 168 families across 15 sites in 9 countries with pathogenic or likely pathogenic variants in PRPH2 were included. Records were reviewed for age at symptom onset, visual acuity, full-field ERG, fundus colour photography, fundus autofluorescence (FAF), and SD-OCT. Images were graded into six phenotypes. Statistical analyses were performed to determine genotype-phenotype correlations.

RESULTS: The median age at symptom onset was 40 years (range, 4-78 years). FAF phenotypes included normal (5%), butterfly pattern dystrophy, …

Outcomes Of Infectious Panuveitis Associated With Simultaneous Multi-Positive Ocular Fluid Polymerase Chain Reaction, Viet Q. Chau, John W. Hinkle, Chris Y. Wu, Parastou Pakravan, Vincent Volante, Jesse D. Sengillo, Patrick C. Staropoli, Darlene Miller, Nicolas A. Yannuzzi, Thomas A. Albini

Wills Eye Hospital Papers

PURPOSE: To evaluate features of infectious panuveitis associated with multiple pathogens detected by ocular fluid sampling.

METHODS: Single-center, retrospective, consecutive case series of patients with aqueous/vitreous polymerase chain reaction testing with >1 positive result in a single sample from 2001 to 2021.

RESULTS: Of 1,588 polymerase chain reaction samples, 28 (1.76%) were positive for two pathogens. Most common pathogens were cytomegalovirus (n = 16, 57.1%) and Epstein-Barr virus (n = 13, 46.4%), followed by varicella zoster virus (n = 8, 28.6%), Toxoplasma gondii (n = 6, 21.4%), herpes simplex virus 2 (n = 6, 21.4%), herpes simplex virus 1 (n …

In This Issuereview Articleoriginal Articlescase Report

Saudi Medical Journal

No abstract provided.

Comparison Of The Genotoxicity Of Propofol And Desflurane Using The Comet Assay In The Lymphocytes Of Patients Who Underwent Lumbar Discectomy: A Randomized Trial, Melike Korkmaz Toker, Basak Altiparmak, Guven Gursoy, Ali Ihsan Uysal, Gulseda Dede, Gulsah Gundogdu, Yavuz Dodurga, Bakiye Ugur

Saudi Medical Journal

Objectives: To compare the genotoxic effects of desflurane and propofol using comet assay in patients undergoing elective discectomy surgery. Methods: This was a randomized controlled study. Patients who underwent elective lumbar discectomy under general anesthesia with propofol or desflurane were included in the study. Venous blood samples were obtained at 4 different time points: 5 minutes before anesthesia induction (T1), 2 hours after the start of anesthesia (T2), the first day after surgery (T3), and the fifth day following surgery (T4). Deoxyribonucleic acid damage in lymphocytes was assessed via the comet assay. Results: A total of 30 patients, 15 in …

Impact Of Change In The Naples Prognostic Score After Neoadjuvant Chemoradiotherapy On Survival In Esophageal Squamous Cell Carcinoma Patients, Haowen Zhang, Xin Xiao, Siyuan Luan, Xiaokun Li, Shangwei Sun, Yong Yuan

Saudi Medical Journal

Objectives: To assess the clinical relevance and prognostic value of changes in the Naples prognostic score (NPS) after neoadjuvant chemoradiotherapy (NACR) among esophageal squamous cell carcinoma (ESCC) patients. Methods: We studied 232 locally advanced ESCC patients who received NACR before undergoing esophagectomy retrospectively. Categorizing individuals into the elevated NPS group and the non-elevated NPS group based on the change in NPS after NACR (ΔNPS > 0 or ∆NPS ≤ 0), we examined and compared the clinicopathological characteristics, survival rates, and postoperative complications between these 2 groups (∆NPS = post-NACR NPS - pre-NACR NPS). Results: Results: Out of the 232 patients enrolled, …

Investigation Of Hematologic Findings Related To Brucellosis In Anatolian Region, Mehmet Çelik, Yusuf Arslan, Ertuğrul Topcu, Mustafa Serhat Şahinoğlu, Deniz Altındağ, Esra Gürbüz, Ebru Atalay, Sümeyye Kışlak Demircan, Salih Emre, Yasemin Kırık, Pınar Yürük Atasoy, Deniz Özer, Davut İpek, Ebru Doğan, Seval Bilgiç Atlı, Evrim Gülderen Kuşçu, Sevil Alkan, Yeliz Çiçek, Esra Yüksekkaya, Özlem Aldemir, Ahmet Şahin, Fatma Yekta Ürkmez, Sevda Özdemir Al, Riyad Boran, Serpil Oğuz Mızrakçı, Mehmet Reşat Ceylan, Hamza Erdoğdu, Süda Tekin

Saudi Medical Journal

Objectives: To investigate the prevalence of hematologic findings and the relationship between hemogram parameters and brucellosis stages in patients. Methods: This multi-center study included patients older than 16 years of age who were followed up with a diagnosis of brucellosis. Patients’ results, including white blood cell, hemoglobin, neutrophil, lymphocyte, monocyte, mean platelet volume, platelet and eosinophil counts were analyzed at the initial diagnosis. Results: In this study 51.3% of the patients diagnosed with brucellosis were male. The age median was 45 years for female and 41 years for male. A total of 55.1% of the patients had acute brucellosis, 28.2% …

Clinical Variables Influencing The Severity Of Diabetes Ketoacidosis, Yara F. Alhamdani, Lojain O. Almadfaa, Abdulmoein E. Alagha

Saudi Medical Journal

Objectives: To evaluate clinical indicators in order to examine the intensity of diabetes ketoacidosis (DKA) episodes in children and adolescents diagnosed with type 1 diabetes mellitus (T1DM). Methods: Data from 156 T1DM patients aged 6 months to 14 years, who presented with DKA to the emergency room, were retrospectively reviewed from 2018 to 2022. Data on demographic characteristics, economic status, initial clinical presentation, glycemic control, DKA severity, and laboratory evaluations were also collected. Results: Diabetes ketoacidosis episodes were more prevalent among male patients during the middle childhood age group. Notably, these episodes displayed seasonal patterns. The severity was found to …

Clinical Presentation And Outcomes Of Patients With Rhabdomyolysis: A Tertiary Care Center Experience, Mohammed Tawhari, Abdulaziz Aldalaan, Rahaf Alanazi, Sarah Aldharman, Turki Alnafisah, Nawaf Alawad, Abdullah M. Alhejji, Abdulrahman Yousef Alhabeeb, Moustafa S. Alhamadh

Saudi Medical Journal

Objectives: To evaluate the clinical and laboratory features, complications, and outcomes of patients with rhabdomyolysis in the Saudi population. Methods: Retrospectives descriptive study of adult patients who presented to King Abdulaziz Medical City (KAMC) withrhabdomyolysis between January 2016 and December 2022. Results: Most of the participants (84.5%) were male, with a median age of 41 years and a body mass index of 26.5 kg/m 2 . Medications, mainly statins (22.4%) and illicit drugs (15.5%), constituted the root causes of rhabdomyolysis in the cohort (44.8%). The most common presenting complaints were myalgia (63.8%) and fatigue (37.9%). More than one-third of the …

Musculoskeletal Disorders Of The Upper And Lower Limb: Prevalence Among Patients In Eastern Province, Saudi Arabia, Ali M. Alshami

Saudi Medical Journal

Objectives: To determine the prevalence of upper and lower limb musculoskeletal (MSK) disorders among adult patients referred to physical therapy. Methods: Data were retrospectively analyzed from electronic health records of patients referred to physical therapy between April 2021 and April 2023. MSK disorders were categorized based on the affected body region (upper or lower limb). Results: A total of 11,243 patients were referred to physical therapy, of whom 4,156 (37%) had MSK disorders. The 4 most commonly affected regions were the knee (27.7%), followed by the shoulder (26.9%), the ankle/foot (14.9%), and the wrist/hand (11.8%). Within each region, the most …

Impact Of Breathing Control Training Program On Sonographic Quantification Of Abdominal Vasculature, Mahasin G. Hassan, Afnan M. Alotaibi, Raghad H. Altuwaym, Reem H. Alnuwaysir, Renad B. Alharbi, Lama M. Alnajashi, Mayer K. Alsaber, Hetaf F. Aldakan, Halima M. Hawesa, Zohida A. Abdelgabar, Asma S. Aldahes, Mohammed G. Yaqob

Saudi Medical Journal

Objectives: To compare vascular scanning parameters (vessel diameter, peak systolic velocity, end-diastolic velocity, and resistive index) and scanning time before and after breathing control training program for selected abdominal vessels. Methods: This study was pre and post quasi-experimental. The researchers designed a breathing training program that gives participants instructions through a video describing breathing maneuvers. Data were collected at the ultrasound laboratory/College of Health and Rehabilitation Sciences in Princess Nourah bint Abdul Rahman University, Riyadh, Saudi Arabia from January 2023 to November 2023. About 49 volunteers at the university participated in the study. Scanning was performed two times for the …

Bilateral Renal Lymphangiectasia: Literature Review Of A Rare Entity, Abdullah Ayed, Shahzada Khalid Sohail, Syeda Fatima Rizvi, Raed I. Alwadai

Saudi Medical Journal

Renal lymphangiectasia (RL) is a rare condition in which lymphatic vessels are dilated giving rise to cyst formation in peripelvic, perirenal and intrarenal locations. Knowledge about RL is limited and based upon individual case reports. This can be genetic or acquired. There is no significant association with any gender or age. It can be manifested as focal or diffuse forms and can be unilateral or bilateral. Most of the cases present with abdominal or flank pain. The diagnosis is based on radiological imaging. Due to rarity of diseases, it has potential to be misdiagnosed as other cystic disease of kidneys. …

Insights And Considerations On Cftr Variant Reporting In A Study Of Cystic Fibrosis Patients In Saudi Arabia Cftr 1548del G And 1549del G: Navigating The Discovery Of Novel Mutations

Saudi Medical Journal

No abstract provided.

Can Probiotics Plus Vitamin D Supplements Benefit People With Schizophrenia?

Saudi Medical Journal

No abstract provided.

Can Artificial Intelligence Techniques Help Clinicians Assess And Treat Patients With Bone Fractures?

Saudi Medical Journal

No abstract provided.

Who Reports Widespread Overuse Of Antibiotics In Patients Hospitalized With Covid-19

Saudi Medical Journal

No abstract provided.

Borderplex Business Barometer, Volume 8, Number 5, Thomas M. Fullerton Jr., Steven L. Fullerton

Border Region Modeling Project

No abstract provided.

Ethical Imperatives In Ai-Driven Educational Assessment: Framework And Implications, Ming Soon Tristan Lim

Dissertations and Theses Collection (Open Access)

This dissertation embarks on an extensive exploration of the ethical challenges emerging from the integration of AI in educational assessments. It uncovers the complex interplay between AI and the ethical imperatives these technologies pose within educational assessments.

Amidst the rapid development of AI-enabled educational technologies, such as Ubiquitous, Adaptive, and Immersive technologies, this research identifies a notable gap in literature specifically concerning the ethical imperatives and implications of AI in educational assessments. Addressing this gap, the dissertation has three primary objectives: to comprehend and analyze the underpinning educational technologies driving assessments, to elucidate the intricate relationship between AI, ethics, and …

Research On The Impact Of Ai Technology Adoption On Organizational Resilience Of Service Enterprises, Jianlin Deng

Dissertations and Theses Collection (Open Access)

In a time of frequent global economic fluctuations, understanding how service enterprises can sustain stability amid fluctuating environments, and even thrive during crises, has become a significant research focus within the current economic context. Advancements in the digital economy provide service enterprises with new digital technology support, leading to their reduced operational costs and heightened efficiency. Among them, artificial intelligence (AI) technology is highly praised by service enterprises. AI technology is extensively integrated into service enterprises’ daily operations and management decision-making. However, limited research has been conducted on how AI technology can assist these enterprises in navigating external environmental disruptions. …

Is This Behavior Impressive Or Repulsive? The Influence Of Our Ecology On Our Social Evaluations, Kai Lin Lynn Tan

Dissertations and Theses Collection (Open Access)

Sexual unrestrictedness, impulsivity, and seeking immediate gratification—these traits generally carry negative connotations and tend to be frowned upon. However, are they necessarily maladaptive? Evolutionary psychologists map these traits onto a behavioural cluster known as a fast life strategy. While a wide body of work has examined many types of prejudices (e.g., sexism, ageism, racism, classism, attractiveness bias etc.) the literature has yet to examine prejudices against people who display behaviours that lie on the life history strategy continuum. I propose that in our modern world where life is relatively predictable and mortality rates are lower than in ancestral times, there …

Recommender System Design And Multi-Channel Pricing: Personalization Strategies For Online Platforms, Hao Zhang

Dissertations and Theses Collection (Open Access)

The advancement of mobile technology and rising consumer demands have contributed to the unprecedented growth of online platforms. In online platforms, recommender systems connect with multistakeholders who have different interests. Designing recommender systems to balance the benefit of multistakeholders is important for these platforms. In addition, price is an important factor influencing consumers’ purchase decisions. An increasing number of online platforms introduce multiple sales channels. Optimizing multiple-channel prices is vital for these platforms. Thus, this thesis designs multistakeholder recommender systems and multi-channel pricing strategies for online platforms through the following two works.

The first work focuses on designing multistakeholder recommender …

Enabling And Optimizing Multi-Modal Sense-Making For Human-Ai Interaction Tasks, Dulanga Kaveesha Weerakoon Weerakoon Mudiyanselage

Dissertations and Theses Collection (Open Access)

The rapid pace of adoption of mixed-reality in tandem with advances in NLP and computer vision have opened up unprecedented opportunities for more naturalistic interaction interfaces which underpin Human-AI collaborative applications such as spatial computing and interactive conversational agents. One notable example is the emergence of interactive virtual assistants, which facilitate more natural communication of instructions and queries through modalities like voice and text. This trend is driving the development of innovative ubiquitous, mixed-reality computing applications. Such interactive, natural communication is also critical to support advances in human-robot interactive co-working, across a variety of industrial, commercial and home environments. Conventional …

Essays On Weak Identification, Dennis Guo Wei Lim

Dissertations and Theses Collection (Open Access)

This dissertation presents a comprehensive examination of inference techniques for weak instrumental variable (IV) models, crucial in addressing endogeneity and bias in econometric analyses. Comprising two interconnected chapters, the research explores innovative methodologies to enhance the reliability and robustness of IV regression estimations. Chapter 1 is concerned with maximizing the power of tests in the many weak IVs setting. This is done by introducing a novel approach that considers a linear combination of jackknife Anderson-Rubin (AR), jackknife Lagrangian multiplier (LM), and orthogonalized jackknife
LM tests for inference in IV regressions with many weak instruments and heteroskedasticity. Following I. Andrews (2016), …