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Fixed Point Results In Complex Valued Neutrosophic B-Metric Spaces With Application, M. Pandiselvi, M. Jeyaraman

Neutrosophic Systems with Applications

In this manuscript, we introduce the idea of complex-valued Neutrosophic b-metric spaces along with numerous significant illustrations. We provide fixed-point results for contraction maps. To support the main result, we establish the existence and uniqueness of solutions for nonlinear integral equations after the work.

Order Approving Disclosure Statement

Catholic Dioceses in Bankruptcy

No abstract provided.

Second-Order Permutation Variable Importance: Quantifying And Attributing Uncertainty In Future Coastal Risk, Dwight Dinkins

Theses

Sensitivity analysis (SA) systematically assesses and quantifies a model’s uncertainty by examining the impact of parameter variations on the model’s output. An objective of sensitivity analysis is to ascertain model-input parameters that contribute the most to the uncertainty of a model’s output and could serve as a gauge to determine whether a parameter’s variation is suitable, expected, or a realistic representation of the phenomenon being modeled. Incorporating sensitivity analysis for assessing the importance of a model feature is imperative for decision-making. Therefore, as a statistical methodology, SA’s application in investigating coastal regions that are vulnerable to sea-level rise and extreme …

Near-Collapse Of The Geomagnetic Field May Have Contributed To Atmospheric Oxygenation And Animal Radiation In The Ediacaran Period, Wentao Huang, John A. Tarduno, Tinghong Zhou, Mauricio Ibañez-Mejia, Laércio Dal Olmo-Barbosa, Edinei Koester, Eric G. Blackman, Aleksey V. Smirnov, Gabriel Ahrendt, Rory D. Cottrell, Kenneth P. Kodama, Richard K. Bono, David G. Sibeck, Yong Xiang Li, Francis Nimmo, Shuhai Xiao, Michael K. Watkeys

Michigan Tech Publications

Earth’s magnetic field was in a highly unusual state when macroscopic animals of the Ediacara Fauna diversified and thrived. Any connection between these events is tantalizing but unclear. Here, we present single crystal paleointensity data from 2054 and 591 Ma pyroxenites and gabbros that define a dramatic intensity decline, from a strong Proterozoic field like that of today, to an Ediacaran value 30 times weaker. The latter is the weakest time-averaged value known to date and together with other robust paleointensity estimates indicate that Ediacaran ultra-low field strengths lasted for at least 26 million years. This interval of ultra-weak magnetic …

Beauregard Center's Vyas Honored By Acpa, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Multiscale Modeling Of Oxygen Evolution Through Generated Bilayer Porous Transport Layers For Pemwe Performance Improvement, M. Sepe, G.-H. Jung, G.S- Doo, C.-S. Lee, H.-S. Cho, N. Tippayawong, Sirivatch Shimpalee

Faculty Publications

Optimization of proton exchange membrane water electrolyzers (PEMWE) has become a focus of researchers looking for a reliable way to generate power. A vital component to PEMWE operation is the porous transport layer (PTL) on the anode side, which is where oxygen is produced. The PTL must allow water access to the catalyst layer and remove oxygen simultaneously. In this work, a previously developed imaging technique is used to generate bilayer PTL structures. A multiscale modeling approach was used to study the effect of a bilayer PTL on oxygen evolution and PEMWE performance. First, a micro scale model was used …

Table Of Contents, Colorado Technology Law Journal

Colorado Technology Law Journal

No abstract provided.

Correlating The Consequences Of Untreated Dental Caries (Pufa/Pufa Scores) And Body Mass Index Related To Age In A Group Of Egyptian Children: A Correlation Study, Hani Abdulwahab Alattallah, Dalia Moheb

International Arab Journal of Dentistry

Objectives: The present study aimed to investigate the correlation between dental caries and its consequences in terms of pulp involvement, ulceration, fistula, abscess utilizing (PUFA/pufa) indices and specific Body Mass Index (BMI) with reference to age in a group of Egyptian Children.

Methods: A total of 201 children (101 female and 100 male) from Pediatric Dentistry Department in Cairo University having PUFA/pufa ≥1 were included. PUFA/pufa index was used according to the standard procedure to assess the consequence of untreated dental decay. The height and weight of the children were determined using standardized scales. The BMI percentile was …

Aspiring Toward Equitable Benefits From Genomic Advances To Individuals Of Ancestrally Diverse Backgrounds, Ying Wang, Yixuan He, Yue Shi, David C Qian, Kathryn J Gray, Robert Winn, Alicia R Martin

Faculty, Staff and Student Publications

Advancements in genomic technologies have shown remarkable promise for improving health trajectories. The Human Genome Project has catalyzed the integration of genomic tools into clinical practice, such as disease risk assessment, prenatal testing and reproductive genomics, cancer diagnostics and prognostication, and therapeutic decision making. Despite the promise of genomic technologies, their full potential remains untapped without including individuals of diverse ancestries and integrating social determinants of health (SDOHs). The NHGRI launched the 2020 Strategic Vision with ten bold predictions by 2030, including "individuals from ancestrally diverse backgrounds will benefit equitably from advances in human genomics." Meeting this goal requires a …

Agency Deference After Loper: Expertise As A Casualty Of A War Against The “Administrative State”, Michael M. Epstein

Brooklyn Law Review

Chevron deference has been a foundational principle for administrative law for decades. Chevron provided a two-step analysis for determining whether an agency would be given deference in its decision-making. This deferential test finds its legitimacy on the grounds of agency expertise and accountability. However, when the Supreme Court of the United States granted certiorari in Loper Bright Enterprise v. Raimondo, it positioned itself to potentially overrule or severely limit Chevron. An overruling of Chevron would place judicial deference to administrative agency decisions in peril by allowing courts to substitute their own views over the informed opinions of agency experts. This …

Dombeck, Peggy, Lydia Wampold

Bronx Jewish History Project

Peggy Dombeck grew up in the East Bronx near Parkchester. She greatly enjoyed her childhood and was always playing games with kids in the neighborhood. She especially enjoyed ice skating and rollerblading, often heading into Manhattan alone on the subway to go ice skate. She also fondly recalls the ice cream man coming by everyday in his truck when she was a child or walking to the candy store around the corner and getting an ice cream cone for 10 cents. The building she grew up in was mainly Jewish, however her family was not very religious. She does however …

Information Literacy Instruction Services At Rural Community Colleges, Fall 2019 Through Ay 2021/22, Heather Posey Vandyne

Library Faculty Publications

This exploratory study examines the instructional practices of two-year institutions located in rural areas during the onset of the Coronavirus pandemic in 2020 and the two academic years that follow. Since the virus commonly known as COVID-19 first made its way to the United States in March 2020, three classes of community college students have had an introduction to higher education unlike any other in living memory. The mixed method approach consists of a survey aimed towards rural college librarians and subsequent in-depth interviews. This study identifies attempts to retain connections with faculty and students, as well as adjustments in …

Development Of Modular High Powered Rocketry Kit For Rocketry Workshop Course, Justin Thomas Bump, Seth Lakota Bunt, Sean Brendan Joyce

Honors Capstone Projects and Theses

No abstract provided.

Employment Training For Graduating Seniors Who Have An Intellectual Disability, Miriam Jeannetta Bohles

Walden Dissertations and Doctoral Studies

The problem that was addressed in this study was that local high school students with intellectual disabilities exit their high school community-based vocational program without sufficient skills required to attain meaningful employment. The purpose of this basic qualitative study was to examine local high school educators’ perceptions about the instruction of employability skills in the community-based vocational program and the additional instruction needed to enhance students’ ability to attain meaningful employment. The conceptual framework was based on Kolb’s experiential learning theory. The research questions focused on skills educators need to incorporate in a community-based vocational program curriculum. Data were obtained …

Kenyon Collegian - May 2, 2024

The Kenyon Collegian

No abstract provided.

Tsyn-Seq: A T-Cell Synapse-Based Antigen Identification Platform, Yimei Jin, Takahiko Miyama, Alexandria Brown, Tomo Hayase, Xingzhi Song, Anand K Singh, Licai Huang, Ivonne I Flores, Lauren K Mcdaniel, Israel Glover, Taylor M Halsey, Rishika Prasad, Valerie Chapa, Saira Ahmed, Jianhua Zhang, Kunal Rai, Christine B Peterson, Gregory Lizee, Jennifer Karmouch, Eiko Hayase, Jeffrey J Molldrem, Chia-Chi Chang, Wen-Bin Tsai, Robert R Jenq

Faculty, Staff and Student Publications

Tools for genome-wide rapid identification of peptide-major histocompatibility complex targets of T-cell receptors (TCR) are not yet universally available. We present a new antigen screening method, the T-synapse (Tsyn) reporter system, which includes antigen-presenting cells (APC) with a Fas-inducible NF-κB reporter and T cells with a nuclear factor of activated T cells (NFAT) reporter. To functionally screen for target antigens from a cDNA library, productively interacting T cell-APC aggregates were detected by dual-reporter activity and enriched by flow sorting followed by antigen identification quantified by deep sequencing (Tsyn-seq). When applied to a previously characterized TCR specific for the E7 antigen …

Fam86a Methylation Of Eef2 Links Mrna Translation Elongation To Tumorigenesis, Joel William Francis, Simone Hausmann, Sabeen Ikram, Kunlun Yin, Robert Mealey-Farr, Natasha Mahealani Flores, Annie Truc Trinh, Tourkian Chasan, Julia Thompson, Pawel Karol Mazur, Or Gozani

Faculty, Staff and Student Publications

eEF2 post-translational modifications (PTMs) can profoundly affect mRNA translation dynamics. However, the physiologic function of eEF2K525 trimethylation (eEF2K525me3), a PTM catalyzed by the enzyme FAM86A, is unknown. Here, we find that FAM86A methylation of eEF2 regulates nascent elongation to promote protein synthesis and lung adenocarcinoma (LUAD) pathogenesis. The principal physiologic substrate of FAM86A is eEF2, with K525me3 modeled to facilitate productive eEF2-ribosome engagement during translocation. FAM86A depletion in LUAD cells causes 80S monosome accumulation and mRNA translation inhibition. FAM86A is overexpressed in LUAD and eEF2K525me3 levels increase through advancing LUAD disease stages. FAM86A knockdown attenuates LUAD cell proliferation and suppression …

Microglial Dynamics And Mechanisms Underlying The Phagocytosis Of Dying Oligodendrocytes, Genaro E. Olveda

Dartmouth College Ph.D Dissertations

Myelin is a complex multilamellar structure, generated by oligodendrocytes, that ensheaths axons and is a vital component for neural processing. Degeneration of both oligodendrocytes and their myelin sheaths is a common pathological feature associated with aging and neurodegenerative diseases. Efficient removal of the cellular and myelin debris is crucial for remyelination and prevention of further degeneration. Microglia, the primary phagocytes of the CNS, are thought to play a key role in this process. To investigate the cellular dynamics underlying microglia-mediated clearance of degenerating oligodendrocytes and myelin sheaths, at the single cell level, we developed a novel model for inducible cortical …

Und Leads Implementation Team Meeting Agenda — May 2, 2024, University Of North Dakota

LEADS Implementation Documents

Agenda for the May 2, 2024 meeting of the UND LEADS Implementation Team. The agenda includes subgroup reports and a discussion titled “Taking Stock and Looking Ahead.”

Peace With Painful Memories, Mona Muzammil, Muzammil Arshad, Washain Muzammil

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

This Book helps you identify and heal from childhood emotional neglect so you can be more connected and emotionally present in your life.

Do you sometimes feel like you’re just going through the motions in life? Do you often act like you’re fine when you secretly feel lonely and disconnected? Perhaps you have a good life and yet somehow, it’s not enough to make you happy. Or perhaps you drink too much, eat too much, or risk too much to feel something good. If so, you are not alone and you may be suffering from emotional neglect.

Are you one …

Validating A 3d-Printed Endovascular Simulator For Use In Training Surgical Residents, Paarth Jain, Jeremy Zack, Lauren Schlegel, Eva Varotsis, Robert S. Pugliese, Michael Nooromid, Babak Abai

Department of Surgery Faculty Papers

Objective: Three-dimensional (3D)-printed endovascular models can be an accessible alternative to expensive, state-of-the-art endovascular simulators but currently lack the rigorous validation needed to be dependable educational tools. This study describes the manufacture of a 3D-printed endovascular model of an aorta and determines the construct validity and preliminary content and face validity of the model. Methods: A 3D-printed aorta was created using segmented data from a patient computerized tomography scan and a FormLabs 3B 3D printer with FormLabs Clear resin. Participants were asked to perform two tasks from a femoral access point: catheterize the contralateral common iliac artery and the superior …

Dual-Systems And Fuzzy-Trace Theory Predictions Of Covid-19 Risk Taking In Young Adults, Sarah M. Edelson, Valerie F. Reyna, Bridget B. Hayes, David M. N. Garavito

Articles

Risk-reduction behaviors are the first line of defense in viral epidemics. Choosing to not engage in risk-reduction behaviors produced millions of preventable deaths from COVID-19. Understanding why this happens and how to predict it is important for theory development and public policy. We took four approaches to this problem: experimentally varying theory-driven predictors (social rewards, transmission risk, and mandatory/voluntary regulations) in choice scenarios, further probing choices in specific scenarios predicted to elicit risk taking, conducting hierarchical regressions with demographic and theory-driven predictors for both scenario types, and conducting corresponding regressions for self-reported protective behaviors. The sample consisted of 247 young …

Factors Affecting Implementation Of Interventions For Oral Health, Substance Use, Smoking And Diet For People With Severe And Multiple Disadvantage: A Community-Based Qualitative Study In England, Neha Jain, Emma A Adams, Emma C Joyes, Gillian Mclellan, Martin Burrows, Martha Paisi, Laura J Mcgowan, Lorenzo Iafrate, David Landes, Richard G Watt, Falko F Sniehotta, Eileen Kaner, Sheena E Ramsay

Peninsula Dental School

Background Populations facing severe and multiple disadvantage (SMD), co-occurring homelessness, substance use and repeat offending have high levels of physical and mental ill-health. Poor oral health is one of the most common health problems in this population and is closely linked with substance use, smoking and poor diet. Issues related to the implementation of interventions among SMD populations to address oral health and related health behaviours are poorly understood. This study aimed to understand the factors that affect implementation (relevance of setting, acceptability and adverse effects of interventions) and the sustainability of interventions targeting oral health, substance use, smoking and …

Spartan Daily, May 2, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 162, Issue 40

Community-Acquired Pneumonia: A Us Perspective On The Guideline Gap, Maricar Malinis, Lilian Abbo, Jose A Vazquez, Luis Ostrosky-Zeichner

Faculty, Staff and Student Publications

Community-acquired pneumonia continues to be one of the most common causes of morbidity and mortality due to infectious disease. The aetiologies, clinical presentations, diagnostic modalities and therapeutic options are changing and outpacing the creation of management guidelines. This educational article summarizes a roundtable activity sponsored by an unrestricted educational grant by Paratek that included US experts discussing these changes and identifying gaps in the current guidelines.

Mdm2 Inhibitors For Cancer Therapy: The Past, Present, And Future, Wei Wang, Najah Albadari, Yi Du, Josef F Fowler, Hannah T Sang, Wa Xian, Frank Mckeon, Wei Li, Jia Zhou, Ruiwen Zhang

Faculty, Staff and Student Publications

Since its discovery over 35 years ago, MDM2 has emerged as an attractive target for the development of cancer therapy. MDM2's activities extend from carcinogenesis to immunity to the response to various cancer therapies. Since the report of the first MDM2 inhibitor more than 30 years ago, various approaches to inhibit MDM2 have been attempted, with hundreds of small-molecule inhibitors evaluated in preclinical studies and numerous molecules tested in clinical trials. Although many MDM2 inhibitors and degraders have been evaluated in clinical trials, there is currently no Food and Drug Administration (FDA)-approved MDM2 inhibitor on the market. Nevertheless, there are …

Examining The Association Between Abstinence From Smoking And Healthcare Costs Among Patients With Cancer, George Kypriotakis, Seokhun Kim, Maher Karam-Hage, Jason D Robinson, Jennifer A Minnix, Janice A Blalock, Yong Cui, Diane Beneventi, Bumyang Kim, I-Wen Pan, Ya-Chen Tina Shih, Paul M Cinciripini

Faculty, Staff and Student Publications

Continuous tobacco use in cancer patients is linked to substantial healthcare costs due to increased risks and complications, whereas quitting smoking leads to improved treatment outcomes and cost reductions. Addressing the need for empirical evidence on the economic impact of smoking cessation, this study examined the association between smoking cessation and healthcare cost utilization among a sample of 930 cancer patients treated at The University of Texas MD Anderson Cancer Center’s Tobacco Research and Treatment Program (TRTP). Applying conditional quantile regression and propensity scores to address confounding, our findings revealed that abstinence achieved through the TRTP significantly reduced the median …

Examining Patient Preferences And Perceptions Of Provider Communication Strategies For Variant Reclassification In Hereditary Cancer Genetic Testing, Mitchell Mcelfresh, Katie Hutto, Gwen Reiser, Bronson Riley, Charlie King

Capstones: Genetic Counseling

Genetic testing plays a role in oncology care by providing insight into patient’s cancer risk and guiding medical management. Variants in genes are classified by their potential to cause disease according to the five-tier system recommended by the American College of Medical Genetics (ACMG). Reclassification of variants is fluid and can lead to both changes in medical management and challenging discussions. Previous research has described methods genetic counselors use for recontacting patients about reclassification, but not whether these methods align with patient preferences. This study employed a mixed methods survey for patients in Nebraska (recruited via flyer and mail) and …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

May 2, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.