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A Rare Case Of Disseminated Extra-Nodal Natural Killer (Nk) Cell Lymphoma, Sowbharnika Arivazhagan, Guru Prasad Parthiban, Sukanthini Subbiah

School of Medicine Faculty Publications

Extranodal Natural Killer (NK)/T-cell lymphoma, nasal type, is rare and frequently found in Asia and South America. It is rarely found in the United States, mainly in the immigrant population. We present a 26-year-old male from Central America who was found to have disseminated NK/T-cell lymphoma. Through this article, we explain how we manage our patient and try to consolidate the treatment modalities for different stages of the disease.

Chemical Herding As A Multiplicative Factor For Top-Down Manipulation Of Colloids, Mark N. Mcdonald, Douglas R. Tree, Cameron K. Peterson

Faculty Publications

Colloidal particles can create reconfigurable nanomaterials, with applications such as color-changing, self-repairing, and self-regulating materials and reconfigurable drug delivery systems. However, top-down methods for manipulating colloids are limited in the scale they can control. We consider here a new method for using chemical reactions to multiply the effects of existing top-down colloidal manipulation methods to arrange large numbers of colloids with single-particle precision, which we refer to as chemical herding. Using simulation-based methods, we show that if a set of chemically active colloids (herders) can be steered using external forces (i.e., electrophoretic, dielectrophoretic, magnetic, or optical forces), then a larger …

Electrochemical Identification Of Metal Chlorides In Eutectic Licl-Kcl Without Prior Knowledge Of Analyte Identities, Tyler Williams, Jason Torrie, Mark Schvaneveldt, Ranon Fuller, Greg Chipman, Devin Rappleye

Faculty Publications

The identities of unknown analytes within four eutectic LiCl-KCl melts were determined using electrochemical methods, simulating the uncertainty of electrochemically probing an electrorefiner salt bath or molten salt nuclear reactor. With a variety of electrochemical methods (e.g. cyclic voltammetry, chronopotentiometry, and square-wave voltammetry), and electroanalytical techniques (e.g. semi-differentiation), every analyte was positively identified, although one false positive occurred because of an unexpected chemical interaction. This study highlights some remaining challenges for the use of electrochemical sensors in nuclear material control and accountability in molten salts: (1) quantification of analytes without the use of calibration curves (e.g. error in property values, …

Data Report: High Downhole Resolution Portable X-Ray Fluorescence Geochemistry Of South Atlantic Transect Basement Cores, Iodp Expeditions 390c, 395e, 390, And 393, M.K. Jonnalagadda, T.M. Belgrano, J.G. Ryan, P.D. Kempton, A.D. Evans, L.J.C. Grant, D.A.H. Teagle, R.M. Coggon, J.S. Reece, J.B. Sylvan, E.R. Estes, Chiara Amadori

School of Geography, Earth and Environmental Sciences

No abstract provided.

How To Mitigate The Risks Of Deployment Of Artificial Intelligence In Medicine?, Sevi̇l Uygun İli̇khan, Mahmut Özer, Hande Tanberkan, Veysel Bozkurt

Turkish Journal of Medical Sciences

The aim of this study is to examine the risks associated with the use of artificial intelligence (AI) in medicine and to offer policy suggestions to reduce these risks and optimize the benefits of AI technology. Artificial intelligence is a multifaceted technology. If harnessed effectively, it has the capacity to significantly impact the future of humanity in the field of health, as well as in several other areas. However, the rapid spread of this technology also raises significant ethical, legal, and social issues. This study examines the potential dangers of AI integration in medicine by reviewing current scientific work and …

Impact Of Celiac Disease In Behçet’S Syndrome Patients: A Study Based On The Database Of Türkiye, Nuray Yilmaz Çakmak, Nai̇m Ata, Serdar Can Güven, Emi̇n Gemci̇oğlu, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇

Turkish Journal of Medical Sciences

Background/Aim Our primary aim was to investigate the effects of concomitant celiac disease (CD) on the clinical characteristics of Behçet’s syndrome (BS) patients. Materials and method The study was a retrospective, nationwide, multi-center study. Turkish Ministry of Health National Electronic Database (e-Nabız) is used under Health Ministry's supervision to extract the subject's data. Statistical Analysis Statistical analyses were made by the Statistical Package for Social Sciences (SPSS) software version 20 (IBM Corp., Armonk, New York). Continuous variables were presented by mean ± standard derivation (SD) or median (min–max) according to normality and compared by student-T test. Results A total of …

The Effect Of Phototherapy Treatment On Serum Melatonin Levels In Term Newborns, Ali̇ Bülbül, İlkay Özmeral Odabaşi, Duygu Besni̇li̇ Açar, Semra Ti̇ryaki̇ Demi̇r

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate the effect of phototherapy treatment on serum melatonin levels in term newborn infants. Material and methods: This study was planned as a single-center, prospective, observational, case-control study. Term infants (gestation week ≥37 weeks) who received at least 6 h of phototherapy due to jaundice constitute the phototherapy group, while the term infants without jaundice and who were exclusively breastfed constitute the control group. Melatonin levels were examined by taking blood samples from babies in both groups at 02:00 at night. Melatonin values were compared between groups. The effect of phototherapy on …

Autism Spectrum Disorder: Evaluation Of Community-Based Screening Program, Mehmet Aki̇f Sezerol, Seli̇n Davun

Turkish Journal of Medical Sciences

Background/aim: This study was conducted to evaluate the results of autism spectrum disorder (ASD) screenings conducted in a region of İstanbul between 2018 and 2023.Materials and methods: This descriptive study was conducted between April 2018 and February 2023 among 25,839 children aged between 18–36 months who had been screened for autism spectrum disorder in Sultanbeyli, İstanbul. Children between 18–36 months are examined and a form consisting of 5 questions and typical symptoms of ASD is filled. Each question is answered as yes or no. Answering yes to at least one of the questions is sufficient to direct them to child …

Cross-Cultural Adaptation Of The Thoracic Outlet Syndrome Index For Turkish-Speaking Patients With Thoracic Outlet Syndrome, Hakki Çağdaş Basat, Fati̇h Özyurt, Muhammed İhsan Kodak, Gülşah Özsoy, Caner Kararti

Turkish Journal of Medical Sciences

Background/aim: Considering that there is no specifically designed scale to measure quality of life (QoL) and level of functioning among Turkish-speaking patients with thoracic outlet syndrome (TOS), the aim of this study was to adapt the Thoracic Outlet Syndrome Index (TOSI) to the Turkish language (TOSI-TR) and analyze its psychometric properties in patients with TOS. Materials and methods: Thirty-nine patients with symptomatic TOS were included in the study. The participants were assessed using the following measures: the QuickDASH, the Western Ontario Rotator Cuff Index (WORC), and a visual analog scale (VAS). The psychometric properties of the TOSI-TR were examined in …

Central Thromboxane A2, Prostaglandin F2Α, Prostaglandin E, And Prostaglandin D Contribute To The Cardiovascular Effects Elicited By Nesfatin-1, Gökçen Güvenç Bayram, Murat Yalçin

Turkish Journal of Medical Sciences

Background/aim: Our recent study revealed that the expression of lipoxygenase (LOX) and cyclooxygenase (COX) enzymes in the hypothalamus is activated by nesfatin-1, leading to the liberation of leukotrienes and prostaglandins (PG), respectively. Moreover, our prior report explained that intracerebroventricular (ICV) nesfatin-1 treatment triggers cardiovascular responses mediated by central LOX and COX enzymes. Building upon our prior reports, the present investigation sought to clarify the role of cardiovascularly active central COX products, such as thromboxane (TX) A2, PGF2α, PGE, and PGD, in orchestrating nesfatin-1-evoked reactions in mean arterial pressure (MAP) and heart rate (HR).Materials and methods: The Sprague Dawley rats, which …

Lindenwood Digest, June 12, 2024, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

From Australia To Nebraska: Researching Social Value, Marilyn R. Schlake, Cheryl A. Burkhart-Kriesel, Jean Ann Fischer, Michelle Krehbiel, Randy Saner

Cornhusker Economics

Globally, there is a growing body of research on social capital through the lens of social value, or how the social connections translate into actions with tangible outcomes impacting livelihoods and well-being. In the United States, social value is a relatively new perspective that will add to the social capital discussion.

Association Between Preoperative Patient Resilience And Patient-Reported Outcomes After Rotator Cuff Repair, Ryan W. Paul, Sydney Streicher, Matthew Wallingford, Michael P. Campbell, Adeeb J. Hanna, Sean Bryan, Fotios Tjoumakaris, Kevin Freedman

Rothman Institute Papers

Background: Mental and emotional health can affect outcomes after orthopaedic surgery, and patient resilience has been found to be significantly related to postoperative functional outcomes. Purpose: To evaluate the relationship between preoperative patient resilience and 2-year postoperative patient-reported outcomes after rotator cuff repair (RCR). It was hypothesized that patients with low preoperative resilience will have worse patient-reported outcomes at 2 years after RCR versus those with high resilience. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who underwent primary arthroscopic RCR in 2020 at a single institution and completed the Brief Resilience Scale (BRS) preoperatively were identified. Other …

Prekindergarten Teachers’ Perspectives Regarding Kindergarten Readiness In Childcare Centers, Adrienne Dominic Stephens

Walden Dissertations and Doctoral Studies

Prekindergarten Teachers’ Perspectives Regarding Kindergarten Readiness in Childcare Centers by Adrienne Dominic Stephens MS, Walden University, 2016 BGS, University of Arkansas at Monticello, 2011 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Education Walden University May 2024

Factors Associated With Digestive System Cancer Screening In Texas., Stella Green

Walden Dissertations and Doctoral Studies

Walden University College of Health Sciences and Public Policy This is to certify that the doctoral study by Stella Green has been found to be complete and satisfactory in all respects, and that any and all revisions required by the review committee have been made. Review Committee Dr. Shanna Barnett, Committee Chairperson, Public Health Faculty Dr. Simone Salandy, Committee Member, Public Health Faculty Chief Academic Officer and Provost Sue Subocz, Ph.D. Walden University 2024 The specific research problem in this study was that despite the high prevalence of digestive system cancer, screening for digestive system cancer has not been optimized, …

How Working Women In Healthcare Perceive Public Transportation And Safety, Assaaformbi Bama

Walden Dissertations and Doctoral Studies

Women use public transportation more frequently than do men. However, most of these transportation systems were not constructed with women in mind. Public transportation systems are accountable for securely transporting people to their destinations, as well as upkeeping protective policies to advocate for fearful passengers. The purpose of this qualitative study was to examine women’s perspectives on public transportation.The research question guiding this study asked women to discuss their safety experiences and needs related to existing public transportation policy. Cooley’s theory of transportation and Friedman’s public safety theory formed the conceptual framework for this study. Purposeful sampling was used to …

Chief Information Security Officers Strategies For Minimizing Cybersecurity Attacks, Jerrell Riggins

Walden Dissertations and Doctoral Studies

Cyberattacks pose a significant threat to corporate operations that depend on computer networks to carry out everyday operations. Technology leaders are concerned about the growing use of ransomware, social engineering, and phishing by cybercriminals to steal data and engage in identity theft, along with the negative impact of cyberattacks on business sustainability. Grounded in protection motivation theory, the purpose of this pragmatic inquiry was to identify and explore the cybersecurity strategies technology leaders used to mitigate cyberattacks that could disrupt their business operational services. The project participants were six technology leaders who used their cybersecurity strategies to mitigate cyberattacks that …

Louisiana Supreme Court Reconsideration Opinion

Catholic Dioceses in Bankruptcy

No abstract provided.

Control Of Cardiometabolic Risk Factors And Their Association With Carotid Intima Media Thickness Among Patients With Type 2 Diabetes Mellitus-Single Center Experience In A Developing Country, Thilak Priyantha Weerarathna, Sarath Lekkamwasam, Iroshani Kodikara, Keddegoda Gamage Piyumi Wasana, Lakmal Fonseka

Turkish Journal of Medical Sciences

Background/aim: Type 2 diabetes mellitus (T2DM) is closely associated with atherosclerotic cardiovascular diseases (ASCVD). The objective of this study was to describe the degree of ASCVD risk factor control and their association with carotid intima-media thickness (CIMT) in T2DM patients followed up at a diabetes clinic in Southern, Sri Lanka. Materials and methods: A crosssectional study was conducted to examine the association between CIMT and nonalcoholic fatty liver disease (NAFLD)in 300 T2DM patients. Both CIMT and its associations with modifiable cardiometabolic risk factors were examined using ultrasonography. The recommended optimal targets for risk factors were defined as glycated hemoglobin (HbA1C) …

Patterns Of Longitudinal Subcortical Atrophy Over One Year In Amnestic Mild Cognitive Impairment And Its Impact On Cognitive Performance: A Preliminary Study, Berri̇n Çavuşoğlu, Duygu Hünerli̇, Derya Durusu Emek Savaş, Görsev Yener, Emel Ada

Turkish Journal of Medical Sciences

Background/aim: Amnestic mild cognitive impairment (aMCI) is a risk factor for dementia, and thus, it is of interest to enlighten specific brain atrophy patterns in aMCI patients. We aim to define the longitudinal atrophy pattern in subcortical structures and its effect on cognition in patients with aMCI.Materials and methods: Twenty patients with aMCI and 20 demographically matched healthy controls with baseline and longitudinal structural magnetic resonance imaging scans and neuropsychological assessments were studied. The algorithm FIRST (FMRIB’s integrated registration and segmentation tool) was used to obtain volumes of subcortical structures (thalamus, putamen, caudate nucleus, nucleus accumbens, globus pallidus, hippocampus, and …

Implications Of Childhood Autism Spectrum Disorder For Maternal Employment: United States Vs. Norway, Idunn Brekke, Andreea Alecu, Celestia Ohrazda, Jiwon Lee

Burton Blatt Institute

Objectives A country’s social welfare system may play an important role in maternal employment. This study compared the labor market participation of mothers of children within the United States (U.S.) and Norway to examine whether the child’s age and severity of the ASD affected mothers’ employment differently between the two countries. Methods The 2019 National Survey of Children’s Health was used for the U.S. analysis, and the 2019 administrative register data were used for the Norwegian analysis. A logit model was used to analyze the impact of a child’s age and ASD severity on maternal employment in the U.S. and …

The Polyaneuploid Cancer Cell State And Therapeutic Resistance: Eco-Evolutionary Dynamics In Structured Populations, Anuraag Bukkuri

USF Tampa Graduate Theses and Dissertations

In this dissertation, I develop and apply eco-evolutionary modeling techniques to understand how the polyaneuploid cancer cell (PACC) state, entered when aneuploid cells exit the cell cycle after S phase and undergo a whole genome duplication, contributes to therapeutic resistance. Since resistance remains one of the primary causes of treatment failure in cancer patients, it is critical to understand how such demographic state transitions allow for acclimatization of cancer cells to therapeutic stressors and how they interact with evolutionary processes to promote irreversible resistance.

In Chapters Two and Three, I lay the foundation for this work. In Chapter Two, I …

Bidirectional Needs Assessment Of Otolaryngology-Head And Neck Surgery Short-Term Surgical Trips In Zimbabwe, Katerina J. Green, Naboth Matinhira, Amiti Jain, Priya Arya, Dontre' M. Douse, Titus Dzongodza, Clemence Chidziva, Joshua P. Wiedermann

Student Papers, Posters & Projects

OBJECTIVES: To describe findings from an otolaryngology-specific needs assessment tool in Zimbabwe.

METHODS: Surveys were developed and shared with Low-Middle Income Country (LMIC) hosting institutions in Zimbabwe and to High-Income Country surgical trip participants (HIC). Respondents were otolaryngologists identified online and through professional networks who had participated in a surgical trip.

RESULTS: The most common procedures Zimbabwe otolaryngologists reported treating were adenotonsillectomy (85.7%), chronic rhinosinusitis (71.4%), chronic otitis (57.1%), and head and neck tumor intervention (57.1%). The most common untreatable conditions that host physicians wanted to treat were skull base surgery (71.4%), flap reconstructions (57.1%), and laryngotracheal reconstruction (57.1%). The …

Efficacy And Safety Of Transcutaneous Electrical Acupoint Stimulation For The Management Of Primary Dysmenorrhoea: Protocol For A Randomised Controlled Trial In China, Weiting Liu, Yanting Ding, Honggang Xie, Hansheng Liu, Changhao Liang

Research outputs 2022 to 2026

INTRODUCTION: Primary dysmenorrhoea (PD) is a common menstrual concern with significant physical and psychosocial impacts. The effectiveness and safety of transcutaneous electrical acupoint stimulation (TEAS) in alleviating PD symptoms remain uncertain due to insufficient evidence. This single-centre, parallel, randomised controlled study intends to evaluate the efficacy and safety of TEAS for PD management. METHODS AND ANALYSIS: 60 participants aged 18-40 years diagnosed with moderate to severe PD will be recruited from Tai'an Hospital of Traditional Chinese Medicine (TCM) and randomly assigned to either a TEAS group or a TEAS-sham group (1:1). The TEAS group will undergo 12 sessions of TEAS …

A Trna Modification Pattern That Facilitates Interpretation Of The Genetic Code, Isao Masuda, Ya-Ming Hou

Department of Biochemistry and Molecular Biology Faculty Papers

Interpretation of the genetic code from triplets of nucleotides to amino acids is fundamental to life. This interpretation is achieved by cellular tRNAs, each reading a triplet codon through its complementary anticodon (positions 34–36) while delivering the amino acid charged to its 3′-end. This amino acid is then incorporated into the growing polypeptide chain during protein synthesis on the ribosome. The quality and versatility of the interpretation is ensured not only by the codon-anticodon pairing, but also by the post-transcriptional modifications at positions 34 and 37 of each tRNA, corresponding to the wobble nucleotide at the first position of the …

Intimacy Without The Chance Of Heartbreak For Richer, For Poorer, In Sickness & In Health, Cynthia Nguyen

Honors Projects

The present study investigates the effect of the COVID-19 pandemic on the consumption of porn, shifts in the production of porn consumed between men and women, and the breakdown of any pattern in adult content via film, pictures, and audio. A quantitative approach was done by using R to analyze data pulled off of Pornhub, Reddit’s GoneWildAudio subreddit, and Archive of Our Own from 2018 to 2023. Statistical inference and modeling is used to attempt to find a pattern in the production of online porn across three mediums over several years before, during, and after the pandemic. Regardless of events …

Using Video Modeling To Improve Hygiene Practices For Students With Significant Cognitive Disabilities, Allison Hovey

Theses and Dissertations

The purpose of this study was to determine the effectiveness of instruction delivered by video to teach hygiene skills to students with significant cognitive disabilities. The independent variable in this study is personal hygiene instruction delivered by a video model. The dependent variable in this study is the ability of a participant to complete a multi-step hygiene task. The dependent variable will be measured during each data session of intervention by two scorers using the same measures and procedures across phases. Visual analysis demonstrated a functional relationship between the hygiene skill video model intervention and an increase in the percentage …

Implications Of Childhood Autism Spectrum Disorder For Maternal Employment: United States Vs. Norway, Idunn Brekke, Andreea Alecu, Celestia Ohrazda, Jiwom Lee

The Lender Center for Social Justice

This cross-national comparison examines how raising a child with Autism Spectrum Disorder affects maternal employment in the U.S. and Norway, highlighting the role of social policies and support systems in shaping outcomes.

A Microfluidic Approach To Study Variations In Chlamydomonas Reinhardtii Alkaline Phosphatase Activity In Response To Phosphate Availability, Alireza Rahnama, Manibarathi Vaithiyanathan, Luis Briceno-Mena, Travis M. Dugas, Kelly L. Yates, Jose A. Romagnoli, Adam T. Melvin

Faculty Publications

Algal growth depends strongly on phosphorus (P) as a key nutrient, underscoring the significance of monitoring P levels. Algal species display a sensitive response to fluctuations in P availability, notably through the expression of alkaline phosphatase (AP) when challenged with P-depletion. As such, alkaline phosphatase activity (APA) serves as a valuable metric for P availability, offering insights into how algae utilize and fix available P resources. However, current APA quantification methods lack single cell resolution, while also being time- and reagent consuming. Microfluidics offers a promising cost-effective solution to these limitations, providing a platform for precise single-cell analysis. In this …

Two Ceps Professors Honored With Nsf Career Awards, Hayley Barnhard

UNH Today Archive

No abstract provided.