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The Role Of Generative Ai In Qualitative Research: Gpt-4'S Contributions To A Grounded Theory Analysis, Ravi Sinha, Idris Solola, Ha Nguyen, Hillary Swanson, Luettamae Lawrence

Instructional Technology and Learning Sciences Faculty Publications

We present reflections on our experience using a generative AI model in qualitative research, to illuminate the AI's contributions to our analytic process. Our analytic focus was a segment of classroom transcript, which captured a teacher introducing scientific theory-building practices to middle school students. We used a grounded theory approach to produce a fine-grained characterization of the teacher's talk moves during the lesson implementation. Our eventual goal is to build a more nuanced conceptualization of responsive teaching in the context of theory-building activities. We involved GPT-4 during the initial exploratory and later focused coding stages. For our analysis of GPT-4's …

The Year-By-Year Primary And Secondary Education Histories Of Homeschooled Individuals And The Implications For Empirical Homeschooling Research, Albert Cheng

Education Reform Faculty and Graduate Students Publications

Many scholars have correctly noted the difficulty of obtaining representative samples of the homeschooling population. Empirical research about homeschooling, therefore, has predominantly relied on convenience samples which lack the external validity that enables one to generalize the findings to other segments of the homeschooling population. Unbiased inferences about the whole of the homeschool population have consequently been difficult to acquire (Kunzman & Gaither, 2022). For instance, empirical findings of college-educated homeschoolers or those from higher socioeconomic backgrounds might not generalize to other populations of homeschoolers (Cheng, 2014; Ray, 2009). Nor might findings about homeschooling families who rely on a structured …

Improving The Language Competencies Of Non-Native Arabic Speakers Through The Communicative Approach, Ahmad Aljanadbah, Ali Al Sharef

All Works

There is no doubt that the communicative approach is one of the most important methodologies in teaching foreign languages to non-native speakers. Therefore, learners are required to use the language as efficiently as a native speaker. This research thoroughly examines the unique attributes of the communicative approach and offers insights into its effective implementation within the classroom setting. The foundation of this study lies in understanding the functional aspects of language and its practical application in real-world contexts. It explores the methodology for teaching communicative Arabic language skills to non-native speakers. Additionally, the research explores the concept of bridging the …

Defining Cis-Regulatory Elements And Transcription Factors That Control Human Cortical Interneuron Development, Gareth Chapman, Julianna Determan, Haley Jetter, Komal Kaushik, Ramachandran Prakasam, Kristen L Kroll

2020-Current year OA Pubs

Although human cortical interneurons (cINs) are a minority population in the cerebral cortex, disruption of interneuron development is a frequent contributor to neurodevelopmental disorders. Here, we utilized a model for deriving cINs from human embryonic stem cells to profile chromatin state changes and generate an atlas of

Noninvasive Assessment Of The Lung Inflammation-Fibrosis Axis By Targeted Imaging Of Cmklr1, Philip Z Mannes, Taylor S Adams, Samaneh Farsijani, Clayton E Barnes, Joseph D Latoche, Kathryn E Day, Jessie R Nedrow, Farida Ahangari, Naftali Kaminski, Janet S Lee, Sina Tavakoli

2020-Current year OA Pubs

Precision management of fibrotic lung diseases is challenging due to their diverse clinical trajectories and lack of reliable biomarkers for risk stratification and therapeutic monitoring. Here, we validated the accuracy of CMKLR1 as an imaging biomarker of the lung inflammation-fibrosis axis. By analyzing single-cell RNA sequencing datasets, we demonstrated

Harmonized Cross-Species Cell Atlases Of Trigeminal And Dorsal Root Ganglia, Shamsuddin A Bhuiyan, Lite Yang, Lisa A Mcilvried, Bryan A Copits, Zachariah Bertels, John S Del Rosario, Allie J Widman, Richard A Slivicki, Jiwon Yi, Robert W Gereau Iv, Et Al.

2020-Current year OA Pubs

Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are specialized to detect and transduce diverse environmental stimuli to the central nervous system. Single-cell RNA sequencing has provided insights into the diversity of sensory ganglia cell types in rodents, nonhuman primates, and humans, but it remains difficult to compare cell types across studies and species. We thus constructed harmonized atlases of the DRG and TG that describe and facilitate comparison of 18 neuronal and 11 non-neuronal cell types across six species and 31 datasets. We then performed single-cell/nucleus RNA sequencing of DRG from both human and the …

Emotional Diplomacy From Tel Aviv To Baghdad: Analyzing The Impact Of Emotional Appeals On Social Media Engagement, Soheil Kafiliveyjuyeh

LSU Doctoral Dissertations

This study investigates the use of emotional appeals in the diplomatic communication of U.S. ambassadors in the Middle East. In the realm of diplomacy, actors might strategically and deliberately exhibit emotions to shape and control how their nation is perceived internationally. The project's primary objective is to explore the effectiveness of emotional appeals in generating social media interactions with politicians’ and ambassadors’ messages, and in building relationships with their target audience through these engagements. Using three studies, I examine the diplomatic communications of U.S. ambassadors in the Middle East by focusing on their utilization of Twitter/X and emotional diplomacy strategies. …

Melvin Boykin

African American Funeral Programs

No abstract provided.

Festival Flamenco Albuquerque 2024, National Hispanic Cultural Center

LAII Events

Friday, June 21, 2024 | 08:00 pm

University of New Mexico | National Hispanic Cultural Center

Festival Flamenco Albuquerque is the oldest and largest flamenco festival outside Spain. It will run from June 21 to 29, featuring 13 performances, 36 music and dance workshops, special tablao flamenco shows, two flamenco parties, a youth and kids camp, a free exhibition, and various flamenco-related movies and documentaries.

Festival Flamenco Albuquerque is organized by the National Institute of Flamenco, one of Albuquerque’s oldest arts nonprofit organizations. Founded in 1982, the Institute offers flamenco dance and music education to youth and families, supporting …

High-Speed Two-Color Scanning Volumetric Laser-Induced Fluorescence, Diego Tapia Silva, Cole J. Cooper, Tracy L. Mandel, Shilpa Khatri, Dustin Kleckner

Faculty Publications

Many problems in fluid mechanics require single-shot 3D measurements of fluid flows, but are limited by available techniques. Here, we design and build a novel flexible high-speed two-color scanning volumetric laser-induced fluorescence (H2C-SVLIF) technique. The technique is readily adaptable to a range of temporal and spatial resolutions, rendering it easily applicable to a wide spectrum of experiments. The core equipment consists of a single monochrome high-speed camera and a pair of ND: YAG lasers pulsing at different wavelengths. The use of a single camera for direct 3D imaging eliminates the need for complex volume reconstruction algorithms and easily allows for …

High-Speed Two-Color Scanning Volumetric Laser-Induced Fluorescence, Diego Tapia Silva, Cole J. Cooper, Tracy L. Mandel, Shilpa Khatri, Dustin Kleckner

Faculty Publications

Many problems in fluid mechanics require single-shot 3D measurements of fluid flows, but are limited by available techniques. Here, we design and build a novel flexible high-speed two-color scanning volumetric laser-induced fluorescence (H2C-SVLIF) technique. The technique is readily adaptable to a range of temporal and spatial resolutions, rendering it easily applicable to a wide spectrum of experiments. The core equipment consists of a single monochrome high-speed camera and a pair of ND: YAG lasers pulsing at different wavelengths. The use of a single camera for direct 3D imaging eliminates the need for complex volume reconstruction algorithms and easily allows for …

Association Between Obstructive Sleep Apnea And Risk Of Benign Vocal Fold Lesions: A Nationwide 9-Year Follow-Up Cohort Study, Yong Tae Hong, Min Gu Kang, Min Gyu Lee, Sang Woo Yeom, Jong Seung Kim

Faculty, Staff and Student Publications

Since obstructive sleep apnea (OSA) affects various parts of the body, there has been little interest about the effect of OSA on voice. The objective of this study was to evaluate the risk of benign vocal fold lesions (BVFL) in OSA patients. This study used data from the National Health Insurance Service (NHIS) database. The study group was defined as the group diagnosed with OSA between 2008 and 2011. Non-OSA groups were selected based on propensity score (PS) matching. Incidence of BVFL among participants during the follow-up was analyzed. Cox proportional hazard regression analyses were performed to evaluate the association …

Multiple Omics Levels Of Chronic Lymphocytic Leukemia, Aleksander Turk, Eva Čeh, George A Calin, Tanja Kunej

Faculty, Staff and Student Publications

Chronic lymphocytic leukemia (CLL) is a lymphoproliferative malignancy characterized by the proliferation of functionally mature but incompetent B cells. It is the most prevalent type of leukemia in Western populations, accounting for approximately 25% of new leukemia cases. While recent advances, such as ibrutinib and venetoclax treatment have improved patient outlook, aggressive forms of CLL such as Richter transformation still pose a significant challenge. This discrepancy may be due to the heterogeneity of factors contributing to CLL development at multiple -omics levels. However, information on the omics of CLL is fragmented, hindering multi-omics-based research into potential treatment options. To address …

Elucidating Immune-Related Gene Transcriptional Programs Via Factorization Of Large-Scale Rna-Profiles, Shan He, Matthew M Gubin, Hind Rafei, Rafet Basar, Merve Dede, Qingnan Liang, Kunhee Kim, Maura L Gillison, Katayoun Rezvani, Weiyi Peng, Cara Haymaker, Sharia Hernandez, Luisa M Solis, Vakul Mohanty, Ken Chen

Faculty, Staff and Student Publications

Recent developments in immunotherapy, including immune checkpoint blockade (ICB) and adoptive cell therapy (ACT), have encountered challenges such as immune-related adverse events and resistance, especially in solid tumors. To advance the field, a deeper understanding of the molecular mechanisms behind treatment responses and resistance is essential. However, the lack of functionally characterized immune-related gene sets has limited data-driven immunological research. To address this gap, we adopted non-negative matrix factorization on 83 human bulk RNA sequencing (RNA-seq) datasets and constructed 28 immune-specific gene sets. After rigorous immunologist-led manual annotations and orthogonal validations across immunological contexts and functional omics data, we demonstrated …

Protocol For Seahorse Analysis Of Ex Vivo Mouse Brown And White Adipose Tissues, Fenfen Wang, Phu M Huynh, Yu A An

Faculty, Staff and Student Publications

The mitochondrial stress test is a gold-standard approach for assessing adipose tissue physiological functions and pathological changes. Here, we present a protocol for conducting Seahorse assays using ex vivo mouse brown and white adipose depots. We describe steps for rehydrating the cartridge, preparing freshly harvested fat depots, placing them onto an islet capture plate, and incubating them in a non-CO2 incubator. We then detail procedures for adding mitochondrial stressor solutions and conducting the mitochondrial stress test using the Seahorse XFe24 Analyzer. For complete details on the use and execution of this protocol, please refer to An et al.1.

A Cocktail Nanovaccine Targeting Key Entry Glycoproteins Elicits High Neutralizing Antibody Levels Against Ebv Infection, Zeyu Yang, Yanran Luo, Yanhong Chen, Qisheng Feng, Mu-Sheng Zeng, Qinjian Zhao, Lixin Liu, Claude Krummenacher, Yi-Xin Zeng, Yongming Chen, Miao Xu, Xiao Zhang

Faculty, Staff and Student Publications

Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies. Considering the complex life cycle of EBV, developing vaccines targeting key entry glycoproteins to elicit robust and durable adaptive immune responses may provide better protection. EBV gHgL-, gB- and gp42-specific antibodies in healthy EBV carriers contributed to sera neutralizing abilities in vitro, indicating that they are potential antigen candidates. To enhance the immunogenicity of these antigens, we formulate three nanovaccines by co-delivering molecular adjuvants (CpG and MPLA) and antigens (gHgL, gB or gp42). These nanovaccines induce robust humoral and cellular responses through efficient …

“She’S Been A Rock”: The Function And Importance Of “Holding” By Social Prescribing Link Workers In Primary Care In England—Findings From A Realist Evaluation, Debra Westlake, Geoffrey Wong, Steven Markham, Amadea Turk, Jordan Gorenberg, Catherine Pope, Joanne Reeve, Caroline Mitchell, Kerryn Husk, Sabi Redwood, Anthony Meacock, Kamal R. Mahtani, Stephanie Tierney

Peninsula Medical School

Social prescribing link workers are recently introduced roles in English primary care. One of their intended functions is to support patients with conditions influenced by the wider, social determinants of health. Their main purpose is to connect people to community resources to meet their nonmedical needs. However, our research reveals that link workers provide not only connections but also what we have described as “holding” for individuals with complex needs, who lack informal networks of support or who are waiting to access services. We explore the concept of holding, its meaning and significance in this context, and consider its consequences. …

Experimental Observation Of A New Attenuation Mechanism In Hcp-Metals That May Operate In The Earth's Inner Core, Simon A. Hunt, Andrew M. Walker, Oliver T. Lord, Stephen Stackhouse, Lewis Schardong, Lora S. Armstrong, Andrew J. Parsons, Geoffrey E. Lloyd, John Wheeler, Danielle M. Fenech, Stefan Michalik, Matthew L. Whitaker

School of Geography, Earth and Environmental Sciences

AbstractSeismic observations show the Earth's inner core has significant and unexplained variation in seismic attenuation with position, depth and direction. Interpreting these observations is difficult without knowledge of the visco‐ or anelastic dissipation processes active in iron under inner core conditions. Here, a previously unconsidered attenuation mechanism is observed in zinc, a low pressure analog of hcp‐iron, during small strain sinusoidal deformation experiments. The experiments were performed in a deformation‐DIA combined with X‐radiography, at seismic frequencies (∼0.003–0.1 Hz), high pressure and temperatures up to ∼80% of melting temperature. Significant dissipation (0.077 ≤ Q−1(ω) ≤ 0.488) is observed along with frequency …

Initiation Of Hnrnpa1 Low-Complexity Domain Condensation Monitored By Dynamic Light Scattering

Faculty, Staff and Students Publications

Biomolecular condensates (BMCs) exhibit physiological and pathological relevance in biological systems. Both liquid and solid condensates play significant roles in the spatiotemporal regulation and organization of macromolecules and their biological activities. Some pathological solid condensates, such as Lewy Bodies and other fibrillar aggregates, have been hypothesized to originate from liquid condensates. With the prevalence of BMCs having functional and dysfunctional roles, it is imperative to understand the mechanism of biomolecular condensate formation and initiation. Using the low-complexity domain (LCD) of heterogenous ribonuclear protein A1 (hnRNPA1) as our model, we monitored initial assembly events using dynamic light scattering (DLS) while modulating …

Identifying Interventions To Improve Diagnostic Safety In Emergency Departments: Protocol For A Participatory Design Study, Hardeep Singh, Kalyan Pasupathy, Prashant Mahajan

Faculty, Staff and Students Publications

Background: Emergency departments (EDs) are complex and fast-paced clinical settings where a diagnosis is made in a time-, information-, and resource-constrained context. Thus, it is predisposed to suboptimal diagnostic outcomes, leading to errors and subsequent patient harm. Arriving at a timely and accurate diagnosis is an activity that occurs after an effective collaboration between the patient or caregiver and the clinical team within the ED. Interventions such as novel sociotechnical solutions are needed to mitigate errors and risks.

Objective: This study aims to identify challenges that frontline ED health care providers and patients face in the ED diagnostic process and …

Alzheimer's Disease Risk Gene Cd2ap Is A Dose-Sensitive Determinant Of Synaptic Structure And Plasticity, Mary E Dickinson, Chih-Wei Hsu, Joshua D Wythe

Faculty, Staff and Students Publications

Tissue clearing is an essential prerequisite for 3D volumetric imaging of larger tissues or organs. Here, we present a detailed protocol for optical, aqueous-based clearing of adult murine tissues using EZ Clear. We describe steps to ensure successful perfusion and fixation of organs from the adult mouse and supply guidelines for optimal lipid removal, refractive index matching, and tissue clearing. Finally, we provide imaging parameters for visualizing both exogenous perfused fluorescent dyes and endogenous fluorescence reporters in the adult mouse. For complete details on the use and execution of this protocol, please refer to Hsu et al.

Analyzing Efficiency Of A Lentiviral Shrna Knockdown System In Human Enteroids Using Western Blot And Flow Cytometry, Sasirekha Ramani, Randle Gallucci, Hala Chaaban, Kathryn Y Burge

Faculty, Staff and Students Publications

Enteroids are in vitro models to study gastrointestinal pathologies and test personalized therapeutics; however, the inherent complexity of enteroids often renders standard gene editing approaches ineffective. Here, we introduce a refined lentiviral transfection protocol, ensuring sufficient lentiviral engagement with enteroids while considering spatiotemporal growth variability throughout the extracellular matrix. Additionally, we highlight a selection process for transduced cells, introduce a protocol to accurately measure transduction efficiency, and explore methodologies to gauge effects of gene knockdown on biological processes.

Clinical Prediction For Surgical Versus Nonsurgical Interventions In Patients With Vertebral Osteomyelitis And Discitis, Jennifer Lee, Miguel A. Ruiz-Cardozo, Rujvee P. Patel, Saad Javeed, Raj Swaroop Lavadi, Catherine Newsom-Stewart, Anton Alyakin, Camilo A. Molina, Nitin Agarwal, Wilson Z. Ray, Michele Santacatterina, Brenton H. Pennicooke

2020-Current year OA Pubs

BACKGROUND: Vertebral osteomyelitis and discitis (VOD), an infection of intervertebral discs, often requires spine surgical intervention and timely management to prevent adverse outcomes. Our study aims to develop a machine learning (ML) model to predict the indication for surgical intervention (during the same hospital stay) versus nonsurgical management in patients with VOD.

METHODS: This retrospective study included adult patients (≥18 years) with VOD (ICD-10 diagnosis codes M46.2,3,4,5) treated at a single institution between 01/01/2015 and 12/31/2019. The primary outcome studied was surgery. Candidate predictors were age, sex, race, Elixhauser comorbidity index, first-recorded lab values, first-recorded vital signs, and admit diagnosis. …

The Relationship Between Abusive Management And Counterproductive Employee Behavior In The United States, Norma Ivette Rosado

Walden Dissertations and Doctoral Studies

Abusive supervision is a kind of destructive leadership that has a detrimental influence on direct subordinates, teams, and the whole business, and counterproductive work behavior has been a critical worry for researchers and managers over the last three decades. It results in undesirable reactions, including workplace deviance, damaging attitudes, and unproductive work habits. Toxic leadership and followership are still relatively new areas of study within the broader field of leadership studies. This study aimed to determine the effects of abusive management on personnel and the business. With counterproductive work behavior (CWB) becoming an increasingly prevalent concept in the workplace, the …

Strategies To Improve Employee Performance, Reduce Turnover, And Improve Company Financial Performance In The Manufacturing Industry, Amih Avegnon Sallah

Walden Dissertations and Doctoral Studies

Manufacturing business leaders are concerned with the lack of employee engagement strategies which can lead to high turnover rates, diminished employee performance, and adverse effects on company financials. Grounded in the theory of engagement, the purpose of this qualitative pragmatic inquiry was to explore employee engagement strategies utilized by manufacturing business leaders to enhance employee performance, mitigate turnover, and bolster company finances. The participants comprised six manufacturing business leaders in the Midwest region of the United States who implemented successful employee engagement strategies. Data were collected using semistructured interviews. Three core themes were identified from the thematic analysis: (a) effective …

The Association Between Mental Health And Fibromyalgia In African Americans, Shalika J. Tisinger

Walden Dissertations and Doctoral Studies

Depression and fibromyalgia can often exacerbate each other and are known to be bidirectional disorders. Chronic pain from fibromyalgia often leads to depression, and depression can cause pain to become worse and affect the nervous system, causing pain. The purpose of this quantitative, binary logistic regression study is to determine if there is an association between mental health and fibromyalgia in African Americans while controlling for cardiovascular disease, chronic kidney disease, arthritis, education level (ie. Some high school, high school graduate, some college or higher), diet, poverty-income-ratio, PIR, diabetes, gender, and age. The socio-ecological model included in this cross-sectional study …

Differences In Art And Music High School Students’ Sat Test Scores From 2006 To 2015, Margaret Ellen Beyer

Walden Dissertations and Doctoral Studies

Academia and education advocates have reported a concern about the elimination of art and music education classes from high school curriculums in the United States. Studies using mean SAT test scores from 1984 and 1994 versions of the SAT test indicated participants who had art and music education classes had higher verbal and mathematical SAT test scores compared to those who did not. However, since revision of the SAT test in 2005, whether students had significantly increased mean SAT test scores with each added year of art and music education participation, and whether students who participated in art and music …

A Case Study Of Layered Border Security And Traffic Problems At Laredo, Texas Port Of Entry, Christopher S. Castacio

Walden Dissertations and Doctoral Studies

Securing the border is the United States Government's top priority to keep terrorists, illegal weapons, nuclear weapons, human smuggling, and drug smuggling from entering the United States during the continuous crossing of legitimate international trades and legitimate travelers. The primary purpose of this qualitative research study was to examine layered U.S. border security and analyze the vehicle and pedestrian flow of traffic problems in Laredo, Texas, Port of Entry. Qualitative methodology was used in this study using seven interviews and open-ended questionnaires. This study's theories were the environment criminology theory, which explored and analyzed the criminal act's environment; and the …

Timely Access To Mental Health Care Within The Veterans Affairs Healthcare System, Irene Perez Cisneros

Walden Dissertations and Doctoral Studies

Background: The Veterans Health Administration is America’s largest integrated healthcare system, providing care at 1,298 healthcare facilities, including 171 medical centers such as Michael E. DeBakey Department of Veterans Affairs Medical Center in Houston, Texas, and 1,113 outpatient healthcare clinics. Studies show that suicide rates are significantly higher among the veteran population than the general population. Purpose: The purpose of conducting a literature review is to identify factors contributing to the lack of timely access to mental health care services internally and externally. It also explored what initiatives need to be implemented to improve the timely access of mental health …

Customer Retention Strategies In Insurance Agencies, Dr. Laquica Patin

Walden Dissertations and Doctoral Studies

Low customer retention has the potential for adverse business outcomes. Insurance agency owners are concerned with low customer retention because it is the number one predictor of businesses becoming insolvent. Grounded in the customer relationship management theory, the purpose of this qualitative pragmatic inquiry was to explore strategies that insurance agency owners can adopt to enhance customer retention and sustainability. The participants were six insurance agency owners with over 5 years of business longevity and exceptional customer retention. Data were collected using semistructured interviews, reviews of business websites, and Facebook and LinkedIn content. Through thematic analysis, three themes were identified: …