Digital Commons Network^™

Pathways To Therapy Resistance: The Sheltering Effect Of The Bone Marrow Microenvironment To Multiple Myeloma Cells, Kuntal Bhowmick, Max Von Suskil, Omar Al-Odat, Weam Othman Elbezanti, Subash C. Jonnalagadda, Tulin Budak-Alpdogan, Manoj K. Pandey

College of Science & Mathematics Departmental Research

Multiple Myeloma (MM) is a malignant expansion of plasma cells in the bone marrow (BM), resulting in a disease characterized by symptoms of end organ damage from light chain secretion, crowding of the BM, and bone lesions. Although the past two decades have been characterized by numerous novel therapies emerging, the disease remains incurable due to intrinsic or acquired drug resistance. A major player in MM's drug resistance arises from its intimate relationship with the BM microenvironment (BMME). Through stress-inducing conditions, soluble messengers, and physical adhesion to BM elements, the BMME activates numerous pathways in the myeloma cell. This not …

Estimation Of Vehicle Traffic Parameters Using An Optical Distance Sensor For Use In Smart City Road Infrastructure, Rafał Burdzik, Ireneusz Celiński, Minvydas Ragulskis, Vinayak Ranjan, Jonas Matijošius

Henry M. Rowan College of Engineering Departmental Research

In recent decades, the dynamics of road vehicle traffic have significantly evolved, compelling traffic engineers to develop innovative traffic monitoring solutions, especially for dense road networks. Traditional methods for measuring traffic volume along road sections may no longer suffice for modern traffic control systems. This is particularly true for induction loops, a widely used method since the last century. In contrast, measuring techniques using microwaves or visible light offer better accuracy but are often hindered by the high cost of sensors. This paper presents new techniques for measuring traffic flow and other parameters that adapt to changing traffic dynamics using …

Island-Wide Characterization Of Agricultural Production Challenges The Demographic Collapse Hypothesis For Rapa Nui (Easter Island), Dylan S. Davis, Robert Dinapoli, Gina Pakarati, Carl P. Lipo

Anthropology Faculty Scholarship

Communities in resource-poor areas face health, food production, sustainability, and overall survival challenges. Consequently, they are commonly featured in global debates surrounding societal collapse. Rapa Nui (Easter Is- land) is often used as an example of how overexploitation of limited resources resulted in a catastrophic popula- tion collapse. A vital component of this narrative is that the rapid rise and fall of pre-contact Rapanui population growth rates was driven by the construction and overexploitation of once extensive rock gardens. However, the extent of island-wide rock gardening, while key for understanding food systems and demography, must be better understood. Here, we …

Island-Wide Characterization Of Agricultural Production Challenges The Demographic Collapse Hypothesis For Rapa Nui (Easter Island), Dylan Davis, Robert J. Dinapoli, Gina Pakarati, Terry L. Hunt, Carl P. Lipo

Anthropology Faculty Scholarship

Communities in resource-poor areas face health, food production, sustainability, and overall survival challenges. Consequently, they are commonly featured in global debates surrounding societal collapse. Rapa Nui (Easter Island) is often used as an example of how overexploitation of limited resources resulted in a catastrophic population collapse. A vital component of this narrative is that the rapid rise and fall of pre-contact Rapanui population growth rates was driven by the construction and overexploitation of once extensive rock gardens. However, the extent of island-wide rock gardening, while key for understanding food systems and demography, must be better understood. Here, we use shortwave …

Impact Of Physical Intimate Partner Violence On Postpartum Depression And Breastfeeding Duration In American Indian And Alaska Native Women, Zoe Resnick Milavetz Green, Marcia Bennett, Abby Hughes-Scalise, James Theisen, Julie Beans

Theses and Graduate Projects

In Alaska, 46 to 91 percent of American Indian and Alaska Native women have experienced physical intimate partner violence (IPV), compared to all women in other states, where the prevalence ranges from seven to 51 percent (Tjaden & Thoennes, 2000). Experiencing physical IPV has negative consequences on the mother’s physical and mental well-being, and has been associated with increased vulnerability to postpartum depression (PPD). Compared to other populations, American Indian and Alaska Native women are at greater risk for PPD due to less access to resources and less research on treatments (MacDorman, 2011). Additionally, American Indian and Alaska Native women …

Runnin’ Bulldogs Finish In The Ita Top 10 For First Time In Program History, Office Of University Communications

Gardner-Webb NewsCenter Archive

After posting a program-best 20 victories during the 2024 spring season, the Gardner-Webb Men’s Tennis team earned the program’s first regional ranking from the Intercollegiate Tennis Association (ITA), which was recently announced by the organization.

Evaluation Of A Clincally-Integrated Community Health Worker Program To Support Adults With Cardiovascular Conditions: Guided By The Prism Framework, Cynthia Orofo

Dissertations

Chronically ill individuals with cardiovascular diseases (CVDs) have been extensively challenged by the complexities of disease management. Cardiovascular disease remains the leading cause of death in the U.S. Although clinically integrated community health worker (cCHW) support interventions have been increasingly implemented to help manage CVDs, a comprehensive analysis of interventions implemented in real-world settings is lacking. The purpose of this study was to observe and evaluate a cCHW support intervention in a real clinical setting serving adults with CVD using an implementation science perspective, guided by the PRISM Framework.

Cardozo Law News Brief: June 21, 2024, Benjamin N. Cardozo School Of Law

Cardozo Law News Brief 2024

Featured Faculty:

• Matthew Wansley
• Alexander Reinert
• Edward Zelinsky
• Jocelyn Getgen Kestenbaum
• Young Ran (Christine) Kim
• Lindsay Nash
• Michel Rosenfeld

Campus News:

• Derrick Hamilton, Deputy Director of the Perlmutter Center for Legal Justice, Featured in The Guardian About Ex-Detective Louis Scarcella, Who Put Him Behind Bars For a Crime He Did Not Commit

Active Molecular Network Discovery Links Lifestyle Variables To Breast Cancer In The Long Island Breast Cancer Study Project., Miao Yu, Qian Li, Georgia Dolios, Peijun Tu, Susan Teitelbaum, Jia Chen, Lauren Petrick

Faculty Research 2024

A healthy lifestyle has been associated with decreased risk of developing breast cancer. Using untargeted metabolomics profiling, which provides unbiased information regarding lifestyle choices such as diet and exercise, we aim to identify the molecular mechanisms connecting lifestyle and breast cancer through network analysis. A total of 100 postmenopausal women, 50 with breast cancer and 50 cancer-free controls, were selected from the Long Island Breast Cancer Study Project (LIBCSP). We measured untargeted plasma metabolomics using liquid chromatography-high-resolution mass spectrometry (LC-HRMS). Using the "enet" package, we retained highly correlated metabolites representing active molecular network (AMN) clusters for analysis. LASSO was used …

Regional Variations In Nabataean Jewelry, Emily Marie Yankura

Theses and Dissertations

The use of jewelry is just one of many avenues for individual self-expression, but even in the most individualistic society it is also a reflection of certain cultural norms, values, and expectations. This thesis is an analysis of Nabataean jewelry in burial contexts from the three main regions of the ancient kingdom - Medina Selah, the Negev, and Petra – with the aim of reaching a better understanding of Nabataean culture through their jewelry. The types of jewelry, materials used in their construction, and many other variables are compared and reveal unique regional variations within an overall Hellenistic style.

Development And Preliminary Validation Of The Internalized Heterosexist Racism Measure For Sexual Minorities Of Color, Juan Pantoja-Patino

Dissertations

Research on intersectional internalized oppression among sexual minorities of color is scant. One of the reasons as to why such oppression is understudied amongst such population is the lack of psychological measures. At the same time, sexual minorities of color are faced with the negative impact of living in a racist and heterosexist society. Therefore, this study is one of first to develop and preliminarily validate the Internalized Heterosexist Racism Measure (IHRM) that evaluates internalized heterosexist racism in sexual minorities of color. By applying an intersectionality framework, the IHRM was generated from an extensive literature review and then reviewed by …

Empathy And Political Skill: Improving Salespeople’S Value Enhancing Behavior Performance, Megan C. Good, Charles H. Schwepker Jr.

Journal of Applied Marketing Theory

Little is known about the interface between empathy and political skill in sales. This study develops a model to reflect these characteristics and their impact on performance. Results from a study of 240 B2B salespeople contradict the a priori assumption that empathy may not be positively related to sales performance and challenge existing stereotypes that salespeople are not empathetic. Importantly, the findings show sellers employing empathy can generate enhanced outcomes. Also, this study extends our understanding that utilizing political influence spreads the benefit of empathy beyond the impact itself. Politically skilled B2B salespeople can better understand and display their empathy …

Exploring The Activities Of Religious Ministers And Festival Tourism At The Christmas Celebration In St. Lalibela, Ethiopia: A Photo-Based Essay, Dagnachew Nega, Alexander Trupp, Yen Pek Teh

International Journal of Religious Tourism and Pilgrimage

Religious festivals represent potential for religious tourism, offering unique cultural and spiritual experiences at destinations. Among the methods for promoting religious festivals as a driver for religious tourism is the use of Photo-based essay tools. While this method is not widely explored in academic research, it holds great promise for tourism and events studies. Photographs have a great value in catching the minds of tourists and creating motivation to travel. This photo essay focuses on the religious ministers at the Christmas celebration in Lalibela, a UNESCO World Heritage site in Ethiopia. Six photo categories were identified. Each category has its …

Ten-Day Holy Land Tour: Long-Lasting Effects On Protestant Travellers, Sherene J. Hattingh

International Journal of Religious Tourism and Pilgrimage

This qualitative study investigated the long-lasting effects of an average tour to the Holy Land on travellers of the same faith. Data were collected using written interviews, diary entries, observations and communications at least one year after Protestant travellers returned from their planned trip. Thematic analysis was used to analyse the data through the three phases of noting, encoding and then interpreting important aspects. The findings show these faith travellers invested themselves into the trip before, during and after, as part of their committed faith formation. Any faith-based reader would be interested in the results that evidence long-lasting effects for …

Factors Affecting Revisit Intentions At Spiritual-Cultural Tourist Destinations In Vietnam, Vien Van Vu, Cong Chi Le, Thinh Van Nguyen

International Journal of Religious Tourism and Pilgrimage

This study explores and tests the different factors affecting the revisit intentions of visitors to spiritual-cultural tourist destinations in Vietnam. A sample of 460 tourists participated in the study, which used AMOS software to test the relationship between the constructs and evaluate their reliability and validity. The research findings confirm that tourist satisfaction helps mediate the relationship between each emotional factor and visitors’ intentions to revisit spiritual-cultural sites. Four factors influencing tourist satisfaction in Vietnam are: (1) individual learning and research needs; (2) personal preference; (3) perceived value of site; and (4) religious belief. The fi ndings from the tests …

Hospitality Services And The Promotion Of Religious Tourism: A Study Of Redemption City, Nigeria, Elizabeth Abiola-Oke, Timileyin Osiobe

International Journal of Religious Tourism and Pilgrimage

Religious tourism is acknowledged as a fast-growing sector within the tourism business, and hospitality services’ role in supporting this growth is important. This study used a quantitative research design to explore the specific function that hospitality services have in promoting religious tourism. Literature study and the distribution of structured research questionnaires to Redemption Resort visitors during monthly programs were the methods adopted for the collection of data. The results show that hospitality services promote religious tourism by providing a safe and comfortable stay, planning religious activities and ceremonies, and providing regional and traditional foods. The study also discusses issues like …

More Or Less?: Telling The Library's Story Through The Academic Program Review, John H. Barnett

Faculty and Staff Publications

Academic libraries regularly provide information to support the accreditation, certification, and periodic review of degree programs. The library portion of the academic program review has traditionally focused on detailing the number of titles and volumes of books in the collection, the age of the collection, and the amount of money the library spends to support the degree program. Employing a "more instead of less" approach, the USC Upstate library uses both narrative and data about collections, services, and initiatives to share the library's story.

This presentation explores what prompted our change in focus and the variety of information we provide. …

Development Of An Online Tool To Support Financial And Legal Planning In Dementia, Irene Tessaro, Sarah M. Hooper, Denise Watt, David Menestres, David Farrell

Faculty Scholarship

Objective: To develop, assess, and refine an online educational tool, Plan for Clarity, to support financial and legal planning in dementia.

Methods: A Delphi mixed-method study with three rounds of anonymous review by lay and professional stakeholders was designed to reach consensus about the content of the online tool and explore the socio-cultural and behavioral factors that could affect access and use.

Results: Consensus showed that the online tool covered key information, knowledge, and communication skills for financial and legal planning. Study themes: 1) the online tool had to be easy to navigate with relevant, easily understood …

Carlos Inestroza-Tosta V. Attorney General United States Of America

2024 Decisions

Agency

Justin De La Cruz Martinez V. Chuck Mathews

2024 Decisions

USDC for the Western District of Pennsylvania

Kenneth Reid V. Warden Canaan Usp

2024 Decisions

USDC for the Middle District of Pennsylvania

Pilgrim Prioritisation Of Religious Activities: Time Use-Based Behavioural Approach In Iran, Hossein Akbari, Abolfazl Hosseini, Mahla Mohammadi

International Journal of Religious Tourism and Pilgrimage

The present study investigates the time-use activities of pilgrims at their religious destination. The time diary was used to describe the behaviour of pilgrims who came on a pilgrimage to the holy shrine of Imam Reza in Mashhad (Iran) in sufficient detail to measure the overall duration and continuous records of activities. According to the findings, pilgrims spend most of their time on necessary and religious activities, respectively. Free time and shopping activities were also among their other activities. Pilgrims were categorised into three clusters: Active Pilgrims, Tourist-Pilgrims, and Non-active or Passive Pilgrims. Active Pilgrims are mostly involved in religious …

Pilgrimage In The Covid-19 Era: Uncovering Supply Side Challenges And Opportunities In Media Representations, Reni Polus, Ismail Shaheer, Naresh P. Nayak

International Journal of Religious Tourism and Pilgrimage

Pilgrimage travel, a common practice across major religions, has historically exhibited remarkable resilience to global crises, owing to the unwavering conviction of its followers. However, the COVID-19 pandemic marked a significant departure from this trend, disrupting pilgrimage tourism, unlike any event since World War II. Despite extensive research on the pandemic’s impact on tourism, limited attention has been directed towards understanding its specific effects on pilgrimage travel. This study seeks to address this gap by examining the challenges and opportunities faced by pilgrimage tourism suppliers in the aftermath of COVID-19. To obtain a comprehensive global perspective, we collected and analysed …

Sentiment Analysis In Relation To Jordan’S Churches - For The Promotion Of Christian Pilgrimage And Religious Tourism In Jordan, Malek Bader

International Journal of Religious Tourism and Pilgrimage

Jordan has many famous tourist destinations of Christian importance, but it is unable to attract many Christian pilgrimage tourists. With churches being the epicenter for Christian pilgrimage tourists, an effort was made to understand the sentiments of the people towards the churches of Jordan. A VADER sentiment analysis was performed on 1,758 tweets after biased data removal and data pre-processing of Twitter data for one year. The results showed that 56% of people had positive sentiments, 27% had neutral sentiments, and only 17% had negative sentiments towards the churches of Jordan. The most frequently appearing words in the total word …

The Academic Influence Of The Camino De Santiago: A Bibliometric Analysis Of Doctoral Research And Indexed Manuscripts, Silvia Díaz-De La Fuente, Virginia Ahedo, María Pilar Alonso Abad, José Manuel Galán

International Journal of Religious Tourism and Pilgrimage

The Camino de Santiago is one of the most recognised cultural pilgrimage routes in the world. Notably, its current influence transcends the strictly inspirational and religious aspects, constituting also a socio-economic, cultural, historical, heritage and tourism cornerstone. This paper analyses, from an innovative bibliometric perspective, the influence of the Camino de Santiago on the academic literature in the period from 1980 to the present. For this purpose, two data sources have been used comparatively: manuscripts indexed in Scopus and doctoral theses. The results reveal a growth of its academic relevance in the last decade, especially in indexed publications. The analysis …

No Evidence For Metabolic Adaptation During Exercise-Related Energy Compensation, E. W. Flanagan, G. Sanchez-Delgado, C. K. Martin, E. Ravussin, H. Pontzer, L. M. Redman

Clinical Research Faculty Publications

The constrained energy model posits that the increased total daily energy expenditure (TDEE) in response to exercise is often less than the energy cost of the exercise prescribed. The mechanisms behind this phenomenon, coined “exercise-related energy compensation” (ExEC), are poorly understood, and it is unknown if ExEC is coupled with metabolic adaptation. Using a randomized controlled 24-week exercise intervention, individuals who demonstrated ExEC were identified. Changes to all components of TDEE and metabolic adaptation were assessed using doubly labeled water over 14 days and room calorimetry over 24-h 48% of individuals exhibited ExEC (−308 ± 158 kcals/day). There were no …

Pyramidal Behavior Skills Training To Increase Behavior Specific Praise In Juvenile Residential Staff, Kyra E. Ludwiszewski

USF Tampa Graduate Theses and Dissertations

Ensuring consistent and effective behavioral treatment services for youth in juvenile residentialfacilities remains a challenge. In recent years, behavioral skills training (BST) has been combined with pyramidal training to teach behavior analytic procedures to staff in various settings. This study aimed to examine the implementation of the pyramidal BST with supervisory and floor staff in a juvenile residential setting that serves high-risk youth exposed to various forms of trauma and victimization. The study employed a multiple baseline design across participants, involving one supervisory staff member and three floor staff members. The objective was to evaluate the impact of pyramidal BST …

June 21, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Distribution Of Variant Rs10974944 Of The Jak2 Gene In Mestizos And Native Americans From Mexico Regarding Worldwide Association Studies With Myeloproliferative Diseases, G Avalos-Navarro, Ad Nuño-Trujillo, K González-Becerra, G Martínez-Cortés, Af Favela-Mendoza, H Rangel-Villalobos

Human Biology Open Access Pre-Prints

The genetic variant rs10974944 (C>G) in the JAK2 gene is associated with a higher risk of myeloproliferative neoplasms (MPNs) by increasing the probability of the somatic mutation V617F in the JAK2 protein. For this reason, we evaluated the distribution of rs10974944 in Mexican populations, including published data from association studies in worldwide populations. We analyzed five Mestizo (admixed) (n= 200) and four Native American population samples from Mexico (n= 200), representing the North, Center, West, and South regions of this country. Therefore, we genotyped rs10974944 by qPCR using Taqman probes. Allele and genotype frequencies were estimated in each population …

Ud In The News June 15-21, University Of Dayton

News Releases

Political scientist Christopher Devine and education law expert Charles Russo continue to share their expertise on issues of the day. Spectrum News 1 Ohio featured Flyer Pitch competition winner From Fatherless to Fearless.