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Articles 360661 - 360690 of 5211493
Full-Text Articles in Entire DC Network
Ponderosa Pine Plant Community Response To High-Severity Wildfire In The Jemez Mountains, Samantha Brodley
Ponderosa Pine Plant Community Response To High-Severity Wildfire In The Jemez Mountains, Samantha Brodley
Biology ETDs
Climate change related temperature increases, and precipitation shifts, along with an increase in fuel loads have rendered large areas of the Southwest more prone to high-severity fire for longer periods of time throughout each year. Fire adapted forests that experience high-severity, stand replacing fires are not consistently experiencing dominant tree species regeneration, and appear, in some cases, to be shifting into novel systems. We collected and analyzed up to 11 years of understory plant community data in ponderosa pine (Pinus ponderosa) forests in the Jemez Mountains, New Mexico, to address early forest regeneration after high and low severity …
Conservation Genomic Investigation Of A Threatened Trout Species Endemic To The Gila River, David Thomas Camak
Conservation Genomic Investigation Of A Threatened Trout Species Endemic To The Gila River, David Thomas Camak
Biology ETDs
Climate change is a looming threat to the persistence of species, especially aquatic, imperiled species. Species native to desert streams are at a particular disadvantage, as many species already face drought, floods, wildfires, and threats from nonnative species, all of which are thought to be exacerbated by climate change. Species such as the threatened Gila Trout (Oncorhynchus gilae) already have small ranges and persist in fragmented and isolated habitats that limits gene flow between populations. Therefore, it is important to understand the current genomic status of such populations to be able to predict the future effects of climate …
Emerging Trends And Challenges Of Metadata In 21st Century Nigerian Academic Libraries, Rose Ezeibe Dr., Daniel Aniekan Aloysius Dr., Godwin M. Nna-Etuk Dr.
Emerging Trends And Challenges Of Metadata In 21st Century Nigerian Academic Libraries, Rose Ezeibe Dr., Daniel Aniekan Aloysius Dr., Godwin M. Nna-Etuk Dr.
Library Philosophy and Practice (e-journal)
This paper examined emerging trends and challenges of metadata in 21st century Nigerian academic libraries. It gave the historical development of metadata and types of library metadata. The functions of metadata in academic libraries were accentuated. Bibliographic Framework (BibFrame) 2.0, Resource Description and Access, Functional Requirements for Bibliographic Records (FRBR) and Functional Requirement for Authority Data (FRAD) were identified as emerging trends of metadata in Nigerian academic libraries. The different online union catalogue and integrated library systems were analyzed. The various challenges and ways of addressing the application of metadata in Nigerian academic libraries were identified. The paper concluded …
Roles Of Nigerian Academic Libraries In Creating Ethical Awareness And Fair Use Legislation Of Digital Intellectual Property, Daniel Aloysius, Victoria David Jimmy, Itoro Effiong Ekanemesang, Ukeme Monday Udoikut
Roles Of Nigerian Academic Libraries In Creating Ethical Awareness And Fair Use Legislation Of Digital Intellectual Property, Daniel Aloysius, Victoria David Jimmy, Itoro Effiong Ekanemesang, Ukeme Monday Udoikut
Library Philosophy and Practice (e-journal)
This paper examined roles of Nigerian academic libraries in creating ethical awareness and fair use legislation of digital intellectual property. It provided the conceptual overview of digital intellectual property and identified the various components of intellectual property. The paper carefully scrutinized the Nigeria Amended Digital Intellectual Property Act 2022 and gave a comprehensive analysis of the ethical awareness of digital intellectual property. The mechanics of fair dealings legislation in Nigeria were explored. The challenges confronting intellectual property in the digital age were identified and the roles of Nigerian academic libraries in providing ethical awareness and fair use legislation of intellectual …
Exploration Of Semiconductor Gain Medium, Resonator, Pump, And Frequency Stabilization For Laser Guide Star Applications, Mingyang Zhang
Exploration Of Semiconductor Gain Medium, Resonator, Pump, And Frequency Stabilization For Laser Guide Star Applications, Mingyang Zhang
Optical Science and Engineering ETDs
Laser Guide Star (LGS) systems are essential for adaptive optics in ground-based astronomical observation. This dissertation demonstrates the feasibility of semiconductor-based LGS systems using the membrane external-cavity surface-emitting laser (MECSEL) platform, employing multiple quantum wells. Various laser cavity configurations were analyzed through simulations and experiments. The in-well pumping method was explored to reduce the quantum defect and address thermal limitations. Multi-pass pumping schemes were designed with Zemax modeling and demonstrated experimentally. To simplify multi-pass pumping, the hybrid-MECSEL (H-MECSEL) design was introduced. COMSOL modeling studied thermal management and thermal lensing effect.
The H-MECSEL achieved approximately 30 W of output power at …
Chemical And Morphological Characterization Of Airborne Particulate Matter At The Jackpile-Paguate Mine, Pueblo Of Laguna, New Mexico: Implications For Potential Metals Exposure, Andreanna C. Roros
Chemical And Morphological Characterization Of Airborne Particulate Matter At The Jackpile-Paguate Mine, Pueblo Of Laguna, New Mexico: Implications For Potential Metals Exposure, Andreanna C. Roros
Earth and Planetary Sciences ETDs
The inhalation of windblown particulate matter (PM) derived from abandoned uranium mines (AUMs) is a potential environmental health risk to Native American communities that live in proximity to these sites. However, the aeolian transport of metal-bearing PM from AUMs, as a potential exposure pathway, has not been investigated in any detail. In this study, we sampled airborne particulate matter within the Jackpile Mine located on the lands of the Pueblo of Laguna, New Mexico using passive sampling methods to understand the characteristics of dust within the mine site. The objective was to determine the elemental concentrations, mineralogy, and morphology of …
Proterozoic Tectonic Evolution Of The Lower Granite Gorge, Grand Canyon, Arizona: A Middle Crustal Record Of Multiple Orogenic Pulses, John M. Bailey
Proterozoic Tectonic Evolution Of The Lower Granite Gorge, Grand Canyon, Arizona: A Middle Crustal Record Of Multiple Orogenic Pulses, John M. Bailey
Earth and Planetary Sciences ETDs
The well-exposed basement transect in the Lower Granite Gorge (LGG) of western Grand Canyon provides a middle-crustal record of suturing crustal blocks during the Proterozoic accretionary history of southwestern Laurentia. Orogenic evolution included at least three stages: (1) subduction-related ~1.75-1.72 Ga volcanic arc magmatism, turbidite deposition, and suturing of arc terranes with different crustal thicknesses; (2) intense northwest-southeast crustal shortening at ca. 1.71-1.68 Ga to form the Vishnu Mountains during the Yavapai orogeny; (3) dextral strike-slip shear zones development at ~1.4 Ga during long-term crustal residence and slow cooling above ~250 °C (~10 km) until ~1.3 Ga. Final cooling from …
Theoretical And Spectroscopic Insights Into Molybdenum- And Tungsten-Sulfur Bonding, Jesse Lepluart
Theoretical And Spectroscopic Insights Into Molybdenum- And Tungsten-Sulfur Bonding, Jesse Lepluart
Chemistry and Chemical Biology ETDs
Molybdenum and tungsten chemistry in biology is dominated by bonding interactions with sulfur and the other chalcogens. The highly-conserved structures of these enzymes’ active sites suggest an early evolution in the history of life, with molybdenum and/or tungsten enzymes likely expressed by the last universal common ancestor. Despite their active site similarities, molybdenum and tungsten enzymes catalyze a diverse array of reactions via equally diverse mechanisms. A deep understanding of the electronic structures of these enzyme active sites and their catalytic intermediates is key to understanding this remarkable chemistry.
The work presented here aims to deepen the understanding of molybdenum …
Agave, Tamarindo Y Jamaica: Testimonios And Movements Of Jotería Rural And Afro-Jotería Rural From The Ranchos And Pueblos Of Rural Southern Mexico, Luis Oswaldo Esparza
Agave, Tamarindo Y Jamaica: Testimonios And Movements Of Jotería Rural And Afro-Jotería Rural From The Ranchos And Pueblos Of Rural Southern Mexico, Luis Oswaldo Esparza
Chicana and Chicano Studies ETDs
This project aims to celebrate and honor resistance strategies by Jotería Rural and Afro-Jotería Rural, who have originally inherited, implemented, and recreated life-affirming survival mechanisms of joy and survival. I accomplished this using a Nagualing Jotería methodologies that humanizes participants by treating their testimonials as legitimate community-based knowledge (Fierros & Delgado-Bernal, 2016). Together, my contributors and I constructed a list of resistance strategies as they tied their experiences in relation to and against repressive colonial rhetoric that continues to be re-articulated in the rural.
Media Road To Violence: A Process Of Racialization Of Rohingya Ethnic Minority, Md Didarul Islam
Media Road To Violence: A Process Of Racialization Of Rohingya Ethnic Minority, Md Didarul Islam
Communication ETDs
ABSTRACT
This dissertation examines how ideologically loaded news media representations advanced the complex and ambiguous process of racialization of the Rohingyas, an ethnic Muslim minority in Myanmar. This study first interrogates the dominant patterns in news sourcing and thematic emphasis in the coverage of Rohingya; secondly, it sheds light on how these representations contribute to reproducing dominant ideologies and power relations. I selected two English-language newspapers published in Myanmar: The Global New Light of Myanmar and the Myanmar Times. I applied the notions of media representation (Hall, 1997), ideology (Althusser, 2007), and racialization (Garner & Selod, 2015) as the central …
White Corn Boy Yellow Corn Girl Find Success On Their Educational Journeys, Sarah Curley
White Corn Boy Yellow Corn Girl Find Success On Their Educational Journeys, Sarah Curley
Teacher Education, Educational Leadership & Policy ETDs
This study aimed to provide a narrative analysis of the storied Diné beliefs and values of three Yellow Corn Girls and one White Corn Boy. My research questions were: How do Diné language and culture influence high school students’ success in high school? What cultural beliefs and values contribute to the success of high school students transitioning into their first year of community college? Utilizing the theoretical framework of The Beauty Way of Life (BWOL) model and its philosophies, I gathered narrative data using individual interviews. I examined the impact of the Diné language, cultural beliefs, and values on their …
Sulfur Sequestration In Anhydrite Through Alteration Of Calcic Wall Rock, Lexi Kenis
Sulfur Sequestration In Anhydrite Through Alteration Of Calcic Wall Rock, Lexi Kenis
Earth and Planetary Sciences ETDs
Heterogeneous gas-solid reactions are suggested as a potential mecha-
nism for sequestering gaseous sulfur through the alteration of calcic wall
rocks. This study explores the concept of a “hierarchy of reactions” pro-
posed by Giggenbach (1987), outlining the interplay between gas components
and redox-related minerals in volcanic wall rocks. Mt. Pinatubo provides a
more felsic composition and more oxidizing conditions compared to previ-
ously studied volcanoes, Kudryavy and Erta Ale (Henley and Fischer, 2021),
and Lascar a more oxidizing case with a similar composition. By employing
thermodynamic models and synthetic melt experiments, evaluations of effi-
ciency of sulfur sequestration across …
Coupled Monte Carlo And Adjoint Depletion Sensitivity Coefficient Methods, Benjamin R. Murphy
Coupled Monte Carlo And Adjoint Depletion Sensitivity Coefficient Methods, Benjamin R. Murphy
Nuclear Engineering ETDs
Recent advances in adjoint-based, continuous-energy Monte Carlo generalized perturbation theory (GPT) sensitivity coefficients are combined with adjoint-based depletion perturbation theory (DPT) sensitivities to obtain fully coupled depletion sensitivity coefficients in OpenMC. These depletion sensitivity coefficients are compared with direct perturbation results and found to have generally good agreement, though discrepancies exist. Some shortfalls of the DPT method include the inefficient initial numeric integration scheme for calculating the DPT sensitivities and the lack of stochastic uncertainty estimates for the DPT sensitivities. However, despite these shortcomings, the methodology provides the means to obtain high fidelity depletion sensitivity coefficients. With refinements to the …
Parallel Multigrid In Time For Chaotic Dynamical Systems, David Alan Vargas
Parallel Multigrid In Time For Chaotic Dynamical Systems, David Alan Vargas
Mathematics & Statistics ETDs
Despite the fact that Parallel-in-Time (PinT) methods are predicted to become necessary to fully utilize next-generation exa- and zettascale machines, there are currently no known practical methods which scale well with the length of the time-domain for chaotic problems, due to exponential dependence of the condition number on the fastest chaotic timescale. I present modifications to the coarse-grid equations along with a novel rediscretization approach which together greatly improve convergence of the multigrid reduction in time (MGRIT) algorithm and allow the first known PinT speedup for a chaotic PDE. The novel Local Shadowing Relaxation (LSR) is presented as an alternative …
High School Teachers’ Perceptions Of The Use Of Achieve3000 As A Literacy Proficiency Intervention, Cameron Ashley Gaines
High School Teachers’ Perceptions Of The Use Of Achieve3000 As A Literacy Proficiency Intervention, Cameron Ashley Gaines
Walden Dissertations and Doctoral Studies
The problem that was addressed through this study was that inconsistency in using a literacy development initiative resulted in no improvement of low literacy scores in April of 2022, as a total of 80.85% of high school students in one learning zone within a Georgia school district scored below literacy proficiency on the Georgia Milestones Assessment System. The purpose of this qualitative study was to examine high school teachers’ perceptions of the use of Achieve3000 as a literacy intervention using the conceptual framework of disciplinary literacy. This study's two research questions focused on high school teachers’ perceptions of using Achieve3000 …
Trps1 Expression Is Frequently Seen In A Subset Of Cutaneous Mesenchymal Neoplasms And Tumors Of Uncertain Differentiation: A Potential Diagnostic Pitfall, Moon Joo Kim, Yi A Liu, Yunyi Wang, Jing Ning, Woo Cheal Cho
Trps1 Expression Is Frequently Seen In A Subset Of Cutaneous Mesenchymal Neoplasms And Tumors Of Uncertain Differentiation: A Potential Diagnostic Pitfall, Moon Joo Kim, Yi A Liu, Yunyi Wang, Jing Ning, Woo Cheal Cho
Faculty, Staff and Student Publications
Although extensively studied in cutaneous epithelial neoplasms, the TRPS1 immunoreactivity in cutaneous mesenchymal neoplasms and tumors of uncertain differentiation (CMNTUDs), such as atypical fibroxanthoma (AFX), remains largely unexplored. We assessed TRPS1 immunoreactivity in 135 CMNTUDs, comprising 46 fibrohistiocytic/fibroblastic tumors, 28 vascular tumors, 24 peripheral nerve sheath tumors (PNSTs), 21 tumors of uncertain differentiation, and 16 smooth muscle tumors. Additionally, we included selected cases of melanoma with spindled cell morphology or desmoplastic features (n = 9) and sarcomatoid squamous cell carcinoma (SSCC) (n = 5) to compare TRPS1 expression patterns with those of AFX. TRPS1 expression was prevalent in dermatofibromas (24/24), …
Author Correction: Brafv600e-Mutant Metastatic Nsclc: Disease Overview And Treatment Landscape, David Planchard, Rachel E Sanborn, Marcelo V Negrao, Aria Vaishnavi, Egbert F Smit
Author Correction: Brafv600e-Mutant Metastatic Nsclc: Disease Overview And Treatment Landscape, David Planchard, Rachel E Sanborn, Marcelo V Negrao, Aria Vaishnavi, Egbert F Smit
Faculty, Staff and Student Publications
No abstract provided.
Nrg Oncology And Particle Therapy Co-Operative Group Patterns Of Practice Survey And Consensus Recommendations On Pencil-Beam Scanning Proton Stereotactic Body Radiation Therapy And Hypofractionated Radiation Therapy For Thoracic Malignancies, Wei Liu, Hongying Feng, Paige A Taylor, Minglei Kang, Jiajian Shen, Jun Zhou, Nathan Y Yu, Terence S Sio, Pranshu Mohindra, Joe Y Chang, Jeffrey D Bradley, Ying Xiao, Charles B Simone, Liyong Lin
Nrg Oncology And Particle Therapy Co-Operative Group Patterns Of Practice Survey And Consensus Recommendations On Pencil-Beam Scanning Proton Stereotactic Body Radiation Therapy And Hypofractionated Radiation Therapy For Thoracic Malignancies, Wei Liu, Hongying Feng, Paige A Taylor, Minglei Kang, Jiajian Shen, Jun Zhou, Nathan Y Yu, Terence S Sio, Pranshu Mohindra, Joe Y Chang, Jeffrey D Bradley, Ying Xiao, Charles B Simone, Liyong Lin
Faculty, Staff and Student Publications
Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combining the advantages of target coverage conformity and critical organ sparing from both PBSPT and SBRT, this new delivery technique has great potential to improve the therapeutic ratio, particularly for tumors near critical organs. Safe and effective implementation of PBSPT SBRT/hypofractionation to treat thoracic malignancies is more challenging than the conventionally fractionated PBSPT because of concerns of amplified uncertainties at the larger dose per fraction. The NRG Oncology and Particle Therapy Cooperative Group Thoracic Subcommittee surveyed proton centers in …
Brain-Age Prediction: Systematic Evaluation Of Site Effects, And Sample Age Range And Size, Nicole Sanford, Jia-Hong Gao, Dongtao Wei, Jiang Qiu, Nerisa Banaj, Dorret I Boomsma, Alan Breier, Henry Brodaty, Randy L Buckner, Jan K Buitelaar, Dara M Cannon, Xavier Caseras, Vincent P Clark, Patricia J Conrod, Fabrice Crivello, Eveline A Crone, Udo Dannlowski, Christopher G Davey, Lieuwe De Haan, Greig I De Zubicaray, Annabella Di Giorgio, Lukas Fisch, Simon E Fisher, Barbara Franke, David C Glahn, Dominik Grotegerd, Oliver Gruber, Raquel E Gur, Ruben C Gur, Tim Hahn, Ben J Harrison, Sean Hatton, Ian B Hickie, Hilleke E Hulshoff Pol, Alec J Jamieson, Terry L Jernigan, Jiyang Jiang, Andrew J Kalnin, Sim Kang, Nicole A Kochan, Anna Kraus, Jim Lagopoulos, Luisa Lazaro, Brenna C Mcdonald, Colm Mcdonald, Katie L Mcmahon, Benson Mwangi, Fabrizio Piras, Raul Rodriguez-Cruces, Jessica Royer, Perminder S Sachdev, Theodore D Satterthwaite, Andrew J Saykin, Gunter Schumann, Pierluigi Sevaggi, Jordan W Smoller, Jair C Soares, Gianfranco Spalletta, Christian K Tamnes, Julian N Trollor, Dennis Van't Ent, Daniela Vecchio, Henrik Walter, Yang Wang, Bernd Weber, Wei Wen, Lara M Wierenga, Steven C R Williams, Mon-Ju Wu, Giovana B Zunta-Soares, Boris Bernhardt, Paul Thompson, Sophia Frangou, Ruiyang Ge, Enigma‐Lifespan Working Group
Brain-Age Prediction: Systematic Evaluation Of Site Effects, And Sample Age Range And Size, Nicole Sanford, Jia-Hong Gao, Dongtao Wei, Jiang Qiu, Nerisa Banaj, Dorret I Boomsma, Alan Breier, Henry Brodaty, Randy L Buckner, Jan K Buitelaar, Dara M Cannon, Xavier Caseras, Vincent P Clark, Patricia J Conrod, Fabrice Crivello, Eveline A Crone, Udo Dannlowski, Christopher G Davey, Lieuwe De Haan, Greig I De Zubicaray, Annabella Di Giorgio, Lukas Fisch, Simon E Fisher, Barbara Franke, David C Glahn, Dominik Grotegerd, Oliver Gruber, Raquel E Gur, Ruben C Gur, Tim Hahn, Ben J Harrison, Sean Hatton, Ian B Hickie, Hilleke E Hulshoff Pol, Alec J Jamieson, Terry L Jernigan, Jiyang Jiang, Andrew J Kalnin, Sim Kang, Nicole A Kochan, Anna Kraus, Jim Lagopoulos, Luisa Lazaro, Brenna C Mcdonald, Colm Mcdonald, Katie L Mcmahon, Benson Mwangi, Fabrizio Piras, Raul Rodriguez-Cruces, Jessica Royer, Perminder S Sachdev, Theodore D Satterthwaite, Andrew J Saykin, Gunter Schumann, Pierluigi Sevaggi, Jordan W Smoller, Jair C Soares, Gianfranco Spalletta, Christian K Tamnes, Julian N Trollor, Dennis Van't Ent, Daniela Vecchio, Henrik Walter, Yang Wang, Bernd Weber, Wei Wen, Lara M Wierenga, Steven C R Williams, Mon-Ju Wu, Giovana B Zunta-Soares, Boris Bernhardt, Paul Thompson, Sophia Frangou, Ruiyang Ge, Enigma‐Lifespan Working Group
Faculty, Staff and Student Publications
Structural neuroimaging data have been used to compute an estimate of the biological age of the brain (brain‐age) which has been associated with other biologically and behaviorally meaningful measures of brain development and aging. The ongoing research interest in brain‐age has highlighted the need for robust and publicly available brain‐age models pre‐trained on data from large samples of healthy individuals. To address this need we have previously released a developmental brain‐age model. Here we expand this work to develop, empirically validate, and disseminate a pre‐trained brain‐age model to cover most of the human lifespan. To achieve this, we selected the …
Intratumoral Microbiome Of Adenoid Cystic Carcinomas And Comparison With Other Head And Neck Cancers, Tatiana V Karpinets, Yoshitsugu Mitani, Chia-Chi Chang, Xiaogang Wu, Xingzhi Song, Lauren K Mcdaniel, Fabiana J Veguilla, Renata Ferrarotto, Lauren E Colbert, Nadim J Ajami, Robert R Jenq, Jianhua Zhang, Andrew P Futreal, Adel K El-Naggar
Intratumoral Microbiome Of Adenoid Cystic Carcinomas And Comparison With Other Head And Neck Cancers, Tatiana V Karpinets, Yoshitsugu Mitani, Chia-Chi Chang, Xiaogang Wu, Xingzhi Song, Lauren K Mcdaniel, Fabiana J Veguilla, Renata Ferrarotto, Lauren E Colbert, Nadim J Ajami, Robert R Jenq, Jianhua Zhang, Andrew P Futreal, Adel K El-Naggar
Faculty, Staff and Student Publications
Adenoid cystic carcinoma (ACC) is a rare, usually slow-growing yet aggressive head and neck malignancy. Despite its clinical significance, our understanding of the cellular evolution and microenvironment in ACC remains limited. We investigated the intratumoral microbiomes of 50 ACC tumor tissues and 33 adjacent normal tissues using 16S rRNA gene sequencing. This allowed us to characterize the bacterial communities within the ACC and explore potential associations between the bacterial community structure, patient clinical characteristics, and tumor molecular features obtained through RNA sequencing. The bacterial composition in the ACC was significantly different from that in adjacent normal salivary tissue, and the …
Clinical And Genomic Landscape Of Ras Mutations In Gynecologic Cancers, Ji Son, Yingao Zhang, Heather Lin, Oriol Mirallas, Pablo Alvarez Ballesteros, Natalie Clark, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon N Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong
Clinical And Genomic Landscape Of Ras Mutations In Gynecologic Cancers, Ji Son, Yingao Zhang, Heather Lin, Oriol Mirallas, Pablo Alvarez Ballesteros, Natalie Clark, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon N Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong
Faculty, Staff and Student Publications
Purpose: We aimed to describe RAS mutations in gynecologic cancers as they relate to clinicopathologic and genomic features, survival, and therapeutic implications.
Experimental design: Gynecologic cancers with available somatic molecular profiling data at our institution between February 2010 and August 2022 were included and grouped by RAS mutation status. Overall survival was estimated by the Kaplan-Meier method, and multivariable analysis was performed using the Cox proportional hazard model.
Results: Of 3,328 gynecologic cancers, 523 (15.7%) showed any RAS mutation. Patients with RAS-mutated tumors were younger (57 vs. 60 years nonmutated), had a higher prevalence of endometriosis (27.3% vs. 16.9%), and …
Antitumor Activity Of A Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting Lgr5 In Preclinical Models Of Neuroblastoma, Jianghua Tu, Yukimatsu Toh, Adela M Aldana, Jake J Wen, Ling Wu, Li Li, Kendra S Carmon, Qingyun J Liu
Antitumor Activity Of A Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting Lgr5 In Preclinical Models Of Neuroblastoma, Jianghua Tu, Yukimatsu Toh, Adela M Aldana, Jake J Wen, Ling Wu, Li Li, Kendra S Carmon, Qingyun J Liu
Faculty, Staff and Student Publications
Neuroblastoma (NB) is a cancer of the peripheral nervous system found in children under 15 years of age. It is the most frequently diagnosed cancer during infancy, accounting for ~12% of all cancer-related deaths in children. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a membrane receptor that is associated with the primary tumor formation and metastasis of cancers in the gastrointestinal system. Remarkably, high levels of LGR5 are found in NB tumor cells, and high LGR5 expression is strongly correlated with poor survival. Antibody-drug conjugates (ADCs) are monoclonal antibodies that are covalently linked to cell-killing cytotoxins to deliver the payloads …
Bayesian Varying-Effects Vector Autoregressive Models For Inference Of Brain Connectivity Networks And Covariate Effects In Pediatric Traumatic Brain Injury, Linda Ewing-Cobbs
Bayesian Varying-Effects Vector Autoregressive Models For Inference Of Brain Connectivity Networks And Covariate Effects In Pediatric Traumatic Brain Injury, Linda Ewing-Cobbs
Faculty, Staff and Student Publications
In this article, we develop an analytical approach for estimating brain connectivity networks that accounts for subject heterogeneity. More specifically, we consider a novel extension of a multi-subject Bayesian vector autoregressive model that estimates group-specific directed brain connectivity networks and accounts for the effects of covariates on the network edges. We adopt a flexible approach, allowing for (possibly) nonlinear effects of the covariates on edge strength via a novel Bayesian nonparametric prior that employs a weighted mixture of Gaussian processes. For posterior inference, we achieve computational scalability by implementing a variational Bayes scheme. Our approach enables simultaneous estimation of group-specific …
Organic No-Till Vegetable Production & Protected Agriculture, William Hastings
Organic No-Till Vegetable Production & Protected Agriculture, William Hastings
UNH Cooperative Extension
No abstract provided.
Early Depletion Of Gut Microbiota Shape Oligodendrocyte Response After Traumatic Brain Injury, Kirill Shumilov, Allen Ni, Maria Garcia-Bonilla, Marta Celorrio, Stuart H Friess
Early Depletion Of Gut Microbiota Shape Oligodendrocyte Response After Traumatic Brain Injury, Kirill Shumilov, Allen Ni, Maria Garcia-Bonilla, Marta Celorrio, Stuart H Friess
2020-Current year OA Pubs
BACKGROUND: This study is a cost-effectiveness study of two implementation strategies designed to train therapists in college and university counseling centers to deliver interpersonal psychotherapy. Costs of implementing a train-the-trainer (TTT) strategy versus an expert consultation strategy were estimated, and their relative effects upon therapist outcomes were calculated and compared.
METHODS: Twenty four counseling centers were recruited across the United States. These centers were randomized to either a TTT (experimental) condition, in which an in-house therapist trained other center therapists, or an expert consultation condition, in which center therapists participated in a workshop and received 12 months of ongoing supervision. …
Improving Hypertension Control In Nigeria: Early Policy Implications From The Hypertension Treatment In Nigeria Program, Oluwabunmi Ogungbe, Chibuzor Abasilim, Mark D Huffman, Dike Ojji, Hypertension Treatment In Nigeria Program Team
Improving Hypertension Control In Nigeria: Early Policy Implications From The Hypertension Treatment In Nigeria Program, Oluwabunmi Ogungbe, Chibuzor Abasilim, Mark D Huffman, Dike Ojji, Hypertension Treatment In Nigeria Program Team
2020-Current year OA Pubs
Hypertension poses a significant health burden globally. In Nigeria, hypertension prevalence is on the rise, with low rates of awareness, treatment, and control. This policy brief explores the critical gaps addressed by the Hypertension Treatment in Nigeria (HTN) Program, highlighting its strengths, initial outcomes, and scalability in primary care settings. The HTN Program employs an integrated, multilevel care model based on the World Health Organization's HEARTS technical package, including patient registration and empanelment, team-based care, training and supervision, a standardized treatment protocol, a health information management system, and a drug revolving fund to improve medication accessibility. By December 2023, hypertension …
Short-Term Time-Series Observations Of Phytoplankton Light-Absorption And Productivity In Prydz Bay, Coastal Antarctica, Sarat C. Tripathy, Anvita U. Kerkar, P. Sabu, Sunil K. Padhi, Sudarsana R. Pandi, Amit Sarkar, Bhaskar V. Parli, Rahul Mohan
Short-Term Time-Series Observations Of Phytoplankton Light-Absorption And Productivity In Prydz Bay, Coastal Antarctica, Sarat C. Tripathy, Anvita U. Kerkar, P. Sabu, Sunil K. Padhi, Sudarsana R. Pandi, Amit Sarkar, Bhaskar V. Parli, Rahul Mohan
Biology Faculty Publications and Presentations
The optical characteristics of coastal Antarctic waters exhibit complexity due to the dynamic hydrography influenced by meltwater intrusion, which alters nutrient levels, thermohaline structure, and optically active substances (OAS) regimes. Studies on bio-optical variability and its implications on phytoplankton productivity (PP) are scanty in coastal polar regions. On this backdrop, time-series measurements (72 h at 6 h intervals) of bio-optical properties such as phytoplankton biomass (chlorophyll-a), absorption (aph), and total suspended matter (TSM) concurrently with PP were measured to understand their interplay and variability in relation to the ambient physicochemical settings in the under-sampled Prydz Bay, coastal Antarctica. Our findings …
Performance Feedback Influence On Special Education Teacher Self-Efficacy, Margaret Stout
Performance Feedback Influence On Special Education Teacher Self-Efficacy, Margaret Stout
Doctoral Dissertations and Projects
This quantitative true experimental pretest posttest design research study was conducted to determine the effect two types of performance feedback had on overall special education teacher efficacy and instructional strategies efficacy. Determining the effect is important because teacher efficacy positively impacts student academic outcomes. In-service public school special education teachers who teach students with low incidence disabilities from Virginia were randomly assigned to two different virtual trainings where the Teachers Sense of Efficacy Scale was used as both the pre-training and post-training instrument. An ANCOVA was performed on the data resulting in the first null hypothesis being rejected and the …
Predicting Educator Perceptions Of Tennessee's Teacher Evaluation System: The Role Of Teacher Gender, Years Of Experience, And School Level Taught, Leonida T. Bell
Predicting Educator Perceptions Of Tennessee's Teacher Evaluation System: The Role Of Teacher Gender, Years Of Experience, And School Level Taught, Leonida T. Bell
Doctoral Dissertations and Projects
This quantitative, correlational study aims to determine if a predictive relationship exists between teacher perceptions of Tennessee's teacher evaluation and the linear combination of teacher gender, years of experience, and school-level taught (elementary, middle, high). Although teachers have recognized the current teacher evaluation system, many educators expressed concerns about it. This study is vital in determining teachers' perceptions of the evaluation system. Participants of this study included a sample of 108 certified elementary, middle, and high school teachers from one of the public school districts in southwestern Tennessee. Data were collected via an anonymous, self-paced online survey utilizing a modified …
Exploring The Benefits Of Dual-Language Immersion Programs: A Hermeneutic Phenomenology, Ashley Cunningham
Exploring The Benefits Of Dual-Language Immersion Programs: A Hermeneutic Phenomenology, Ashley Cunningham
Doctoral Dissertations and Projects
The purpose of this hermeneutic phenomenological study was to understand current practices in dual language immersion (DLI) programming, identify biases, and investigate designs for implementing dual language immersion programs to provide consistency between programs in elementary schools in Georgia. The theory guiding this study was Cummins' threshold theory, as it describes the process of language acquisition for young children and the cognitive effects of bilingualism. Selected public elementary dual language immersion teachers in Georgia participated in an individual interview, focus group, and a questionnaire to collect data. Data analysis was used to interpret the findings to answer the central research …