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American Letters--Mary Hunter Austin: Excerpts From The Trail Book (1918)

The International Journal of Ecopsychology (IJE)

No abstract provided.

Poem--Henry Wadsworth Longfellow, "Kéramos" (1844)

The International Journal of Ecopsychology (IJE)

No abstract provided.

Yap1 Knockdown And Panobinostat Treatment Increase Apoptotic Response And Decrease Gene Expression In Ewing Sarcoma Cells, Luna Collazo-Garcia, Alejandra Favela Santos, Madeline Torres-Salazar, Isabella Toscano, Terry Jo Shackleford

Cell and Molecular Methods

Ewing sarcoma (EWS) is considered to be one of the most aggressive pediatric malignancies, often characterized by its dysregulated gene expression driven by oncogenic fusion proteins. The Hippo signaling effector Yes-associated protein 1 (YAP1) has been known in promoting cell proliferation, survival, and therapeutic resistance in multiple cancers. However, its role in Ewing sarcoma response to treatment remains unclear. This study investigated whether YAP1 knockdown enhances the sensitivity of Ewing sarcoma cells to the histone deacetylase inhibitor Panobinostat. Ewing sarcoma, ES8, cells were transfected with a YAP1-targeting siRNA (siYAP1) or a non-targeting control (siControl) and treated with DMSO, 0.1 μM, …

Everolimus Treatment Combined With Akt1 Knockdown Increased Apoptosis And Decreased Cell Proliferation In Ewing Sarcoma Cells, Arisha Arif, Alfie Barcenez, Sophia Ruter, Nicole Vanegas-Riddick, Terry Jo Shackleford

Cell and Molecular Methods

The purpose of this study is to use the gene AKT1, due to the interest in AKT1’s role in cancer cell proliferation, and the drug Everolimus, to determine if combined targeted therapy works as a more efficient therapeutic approach. Ewing Sarcoma has been connected to chromosomal translocations and is most common in pediatric patients. It is most often treated with chemotherapy and local treatments. It may be connected to the gene AKT1 due to how it regulates cell metabolism, growth, and proliferation. The gene mTOR is similarly connected to cell metabolism and proliferation, and is inhibited by the drug Everolimus. …

Everolimus And Sirna-Mediated Mtor Inhibition Reduces Proliferation And Promotes Apoptosis In Ewing Sarcoma Cells, Dylan Calvert, Malorie Martinez, Alexa Miner, Ellis Quiroga, Terry Jo Shackleford

Cell and Molecular Methods

Ewing Sarcoma (ES) is an aggressive pediatric bone cancer characterized by rapid cell proliferation and poor prognosis, making the identification of therapeutic targets critical. One of  the mechanistic targets is rapamycin (mTOR) signaling pathway, which is critical for regulating cell growth, proliferation, and survival. Abnormal activation of the mTOR signaling pathway has been linked to the progression of ES, as it drives uncontrolled cell growth and apoptosis resistance. Because mTOR represents a promising therapeutic target for ES treatment, we hypothesized that inhibiting mTOR activity through an siRNA-mediated knockdown or through Everolimus drug treatment, would reduce cell proliferation and promote ES …

Subversive Order: Gendered Institutions, Gang Networks, And Survival In American Women’S Prisons., Amber Morris

Dissertations - ALL

Popular culture often depicts prison subcultures and gangs, yet these portrayals obscure the complexity of survival behind bars. Existing scholarship on prison life overwhelmingly focuses on men, emphasizing masculinity, race, safety, and community as the primary drivers of behavior. Women, however, represent the fastest-growing prison population in the United States, and their experiences remain under-theorized. This dissertation asks a different question: What if pseudo-families, mentorship networks, and subcultural norms aren't just coping mechanisms‚ what if they're governance institutions? Further, what if women build these systems in prisons not because they're emotional or naturally relational, but because formal institutions don't provide …

Characterizing The Spatiotemporal Evolution Of Midlatitude Seasonal Snowpacks Using Various Ground-Based Observations, Madison June Gunn

Dissertations - ALL

Recent warming in the last few decades has caused widespread changes in the global climate, especially in areas that experience snow events or contain permafrost environments. In the northern United States, our winter seasons are decreasing in length, the overall snowpack depth is decreasing, and the availability of springtime snowmelt is less. This is leading to a shift of a more rain dominated climate especially in the northeastern United States, impacting forest health, water resource availability, and winter tourism. Thus, studying how these seasonal snowpacks are changing soon is extremely important for climate and human health. This dissertation examines a …

Examining How Disability Resource Professionals In Higher Education Enact Whiteness In Maintaining Power And Privileged Structures, Paula Possenti-Perez

Dissertations - ALL

This dissertation examines how Whiteness operates with the delivery of disability-related accommodations on US college campuses. The research in this study focused on three questions: (a) How do disability resource professionals individually begin to make sense of their Whiteness personally? (b) How do disability resource professionals recognize and account for their White racialized frame and Whiteness in their individual professional judgment and decision-making? (c) How do disability resource professionals describe the ways Whiteness as ideology manifests in the field of disability resources, through its professional norms and systemic practices across disability resources in higher education? Twelve White disability resource professionals, …

Mapping The Rigid Landscapes Of Disordered Networks And Active Solids, Tyler Hain

Dissertations - ALL

Biological systems are able to exhibit remarkable and exotic mechanical properties by tuning their microscopic internal degrees of freedom in order to accomplish global functions. One of the most interesting mechanical behaviors of some such materials is the ability to transition between stiff solid-like states and soft fluid-like states in order to initiate specific flow patterns or tune their mechanical response. Not only this, but they are able to selectively cross this transition while also being optimized for other functions. In this dissertation I explore numerical and analytical methods for mapping the landscapes of states on the edge of rigidity …

The Predictive Validity Of Casual Dating Advice For Early-Stage Romantic Relationship Outcomes, Jayda Patrice Felder

Dissertations - ALL

For years, relationship scientists have advocated for more research on casual dating, which can refer to the period of time between a first date and coupling among a romantic dyad, as well as the general period of time an individual is on the dating market evaluating potential partners. Though much is known about established romantic relationships, casual dating and early relationship development remain understudied. To that end, there are many ongoing debates among laypeople about casual dating advice that should be followed (or abandoned) in order to make the best partner choice and experience the best relationship outcomes, yet empirical …

Three Essays On Trust In American Society, Devin Caramma

Dissertations - ALL

Social and political trust are paramount for healthy, democratic functioning, with social trust mattering for cooperative behavior or political action and political trust weighing more heavily for policy compliance, democratic satisfaction, and political participation. Across the last half century, trusting attitudes between citizens and towards government declined precipitously, but this decline has been less dramatic among partisans. What drives the relationship between partisan identification and social trust? Does perceived value congruence with a group cause social trust to increase? Do objective signals of ambient air pollution affect trust in state government? These questions are interrogated and tested across three papers …

High Courts During Democratic Decline, Alice Cho Timken

Dissertations - ALL

This dissertation is a collection of three papers that explore the roles that high courts play during democratic decline and the incentives and conditions that explain them. Each uses a different methodological approach to address this central question. Paper 1. “The Political Foundations of Independent Judicial Review Revisited: Modeling Political Insurance” Episodes of democratic decline routinely feature reductions in judicial independence. Which mechanisms connect these phenomena? I model political insurance theory to explore how the internal workings of a foundational theory may help explain the nature of judicial independence during threats to democracy. I find that political competition must be …

Characterizing Capacitance Of Josephson Junctions For Quantum Devices, Bradley Gordon Cole

Dissertations - ALL

The field of quantum computing is growing at a rapid rate with the promise of dramatic improvements in the ability to solve critical computational problems. A leading approach for implementing fault-tolerant quantum computers is based on superconducting circuits containing Josephson junctions to form qubits. These qubits have many attractive qualities, but predicting the device performance requires detailed knowledge of the junction properties. Thus, precise characterization is crucial for realizing different qubit designs. The coherence of superconducting qubits is limited by several sources in the circuit en- vironment. Building a quantum computer requires effort to reduce gate errors caused by decoherence. …

Quasi-Einstein Metrics And Homogeneous Conformally Einstein Manifolds, Nazia Valiyakath

Dissertations - ALL

This thesis investigates a classic question in Riemannian geometry: What is the best metric to put on a Riemannian manifold? It combines two projects that explore different aspects of this question. The first project studies nilpotent and unimodular solvable Lie groups that admit m-quasi-Einstein metrics (M,g,X) with X a left-invariant vector field, which we call totally left-invariant quasi-Einstein metrics. We give a complete classification of nilpotent Lie groups admitting such metrics, showing that this occurs if and only if the group is isomorphic to Heisenberg Lie group. For unimodular solvable Lie groups S, we prove that the existence of a …

Systemic Employment Discrimination And Class Actions: The Extent Of Structural Litigation In The United States And Brazil, Ricardo Jose Macedo De Britto Pereira

Dissertations - ALL

This dissertation explores class actions against systemic employment discrimination in the United States and Brazil, adopting a collective perspective that strengthens the enforcement of rights. The study also examines whether affirmative action can be implemented as a remedy without dividing groups or triggering resistance in political scenarios unfavorable to inclusive and diverse work environments. The focus is on institutional responses addressing structures of discrimination through procedural tools that advance reforms and prevent setbacks. The dissertation develops a political and legal theoretical background of collective rights, identifying unequal structures in society and pathways for reform, and examining employers’ authority, labor segmentation, …

Examining The Formation, Participation Dynamics, And Leadership Of Cross-Sectoral And Intergovernmental Networks For Collaborative Watershed Management, Nicholas Oesterling

Dissertations - ALL

Public policies are increasingly relying on collaborative networks of governmental and non-governmental actors to address complex problems for the achievement of policy goals. Public administrators, therefore, are now often facing critical questions of how to collaborate across boundaries (e.g., sector, jurisdiction) in networks for policy implementation. In this dissertation, I address unresolved questions regarding these networks for cross-boundary (i.e., cross-sector, intergovernmental) collaboration. Specifically, this dissertation’s three essays tackle questions regarding how external factors may influence when and where networks form, how voluntary participation occurs within networks over time, and how network leadership may shape network composition and purpose. The first …

Climate Impacts Apple Pollination, Yield And Economic Outcomes Of Farmers, Clémence Riva, Stella Gachoki, Noureddine Adjlane, Danilo Bevk, Yamina Haider, Fani Hatjina, Šimun Kolega, Marin Kovačić, Ioannis Manthos, Zlatko Puškadija, Thomas Sotiropoulos, Bojan Stipešević, Fabrice Requier

All Peer-Reviewed Publications

Animal-mediated pollination is crucial to global food production but is increasingly threatened by environmental degradation, habitat loss and climate change. The extent to which temperature affects pollination services and crop yields is poorly understood. Using standardised monitoring in 33 apple orchards across Europe and Northern Africa over two years, this study assessed how ambient temperature affects flower visitors, fruit set, fruit quality and economic outcomes. Observation-time warm temperatures increased pollinator abundance, particularly of honey bees, while long-term mean annual temperatures enhanced pollination services for apple weight. Apple yield and the economic benefits to farmers increase with temperature, while the role …

Sirna Knockdown Of Rptor Reduces Rptor Expression, Increases Brd4 Expression, And Alters Proliferation And Apoptosis In Ewing's Sarcoma Cells, Sergio Cipriano, David Leavitt, Michael Olivia, Liam Valdez, Terry Jo Shackleford

Cell and Molecular Methods

Ewing sarcoma is a highly aggressive cancer that primarily affects children and young adults. Although treatment options exist, many patients do not respond effectively, showing the need for improved targeted therapies. RPTOR is a key in mTORC1 complex which regulates cell growth, proliferation, and survival. LY2874455 is a selective pan-FGFR inhibitor that targets growth factor signaling pathways involved in tumor progression, and FGFR signaling interacts with pathways such as mTOR, making it a potential target for combination therapies. We hypothesized that silencing RPTOR in Ewing sarcoma cells would disrupt mTOR signaling and alter expression of genes linked to cell survival …

Patentability Of Ai-Assisted Inventions: Guidance, Case Law, And A Roadmap Forward, Zhipeng Zhu

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

Muth's Law: Anticipating Ai Model Collapse, Karl T. Muth

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

Molecules And Monoclonals: The Two-Tiered Patent System, Candi L. Lasarge Ph.D.

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

Against The Whistle: How Congress Can Stop Sports Piracy, Julianna Kapovic

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

Pooling Responsibility: Incentivizing Cable Owners To Safeguard The Global Undersea Network, Kevin Frazier

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

Generative Ai Training And Fair Use: Can Chatgpt Turn Your Favorite Meme Into A Stupid Ghibli Animation?, Liam Donovan

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

Click To Agree: Reassessing Minors' Persona Rights In The Age Of Monetized Social Media, Mackenzie Custer

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

When Knowledge Isn't Free: Legal And Ethical Imperatives Of Protecting Indigenous Intellectual Property, Claire Courter

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

Policing The Perils Of Online Dating: Harassment, Scams, Dark Patterns, Monopoly, And Perverse Incentives, Kevin Chamow

The University of Cincinnati Intellectual Property and Computer Law Journal

No abstract provided.

The Influence Of Prosthetic Obturators On Quality Of Life In Individuals With Maxillectomy Defects, Minseok Kim

Oral Health

Abstract

Introduction: In recent years, there has been a growing focus on understanding the impact of oral cancer on patients' quality of life. Prosthetic rehabilitation techniques, such as maxillary obturators, often in conjunction with reconstructive surgery, have emerged as interventions to address the challenges posed by post-maxillectomy abnormalities.

Objective: This study aims to systematically review and evaluate the effectiveness of maxillofacial prosthetic rehabilitation using obturators in enhancing the quality of life of patients following maxillectomy.

Methodology: Systematic review of identified literature spanning the timeframe from 2000 to 2020 was used. The comprehensive search encompassed widely recognized databases including PubMed, …

Value Of The Non-Enhanced Cardiac Computed Tomography Scan Analysis In Determination Of The Appropriate Coronary Ct Angiography Scan Protocol Improving Image Quality While Minimizing Radiation, Osama A Smettei, Sawsan A Sayed, . Fatin M Ahmed, Tawfeeq H Alharbi, Mohammed Saied, Rami M Abazid

Journal of the Saudi Heart Association

Objective: Coronary computed tomography angiography (CCTA) is a cornerstone in the assessment of coronary artery disease. Despite technological advancements, balancing radiation does with diagnostic image quality remains a challenge. This study evaluates whether assessing preliminary non-enhanced CT scans allows for the optimization of CCTA gating protocols to enhance image quality and minimize radiation exposure.

Methods: We prospectively analyzed 150 patients undergoing CCTA on a 256-slice scanner. Non-enhanced scans were used to identify motion artifacts or anatomical challenges. Based on these findings, a specific gating protocol (prospective, prospective with padding, or retrospective) was selected. This cohort was compared to a …

University Of Minnesota Morris Commencement 2026, Communications And Marketing

UMM Commencement

The University of Minnesota Morris's sixty-third commencement, Saturday, May 9, 2026, 1:30 PM.