Integration Of Intraoperative Data In Interpretable Machine Learning Models To Predict Postoperative Aki In Noncardiac Surgery Patients, Justin Do, Karan H. Shah, Melissa Xu, Andrew Hyunwoo Kim, Vivaswat Suresh, Nidhir Guggilla, Michael Li, Rishi Kothari

Department of Anesthesiology Faculty Papers

OBJECTIVES: We aimed to (1) quantify changes in discrimination when adding intraoperative data to preoperative data and (2) compare tabular machine learning with feature engineering against a time-aware LSTM-based model.

MATERIALS AND METHODS: Retrospective cohort of 46 204 adults undergoing 57 055 eligible noncardiac surgery in the INSPIRE database. We extracted 38 preoperative and 49 intraoperative variables; acute kidney injury (AKI) was defined by KDIGO serum creatinine criteria and modeled as stage 2/3 postoperative AKI. Models were trained on preoperative-only and combined pre- and intraoperative data. Intraoperative series were summarized using eight statistical features for tabular models or integrated directly …

Rheological Protocol To Assess And Optimize Latex Coagulation Dynamics For The Thin Glove Coagulant Dipping Process, Monday U. Okoronkwo, Kok Kong Ng, Wolfram Franke, Gaurav Sant

Chemical and Biochemical Engineering Faculty Research & Creative Works

Many products that directly impact the quality of human life today — gloves, catheters, condoms, and baby bottle teats — are made through the latex-dipping technology. While a variety of methods have been developed – e.g., particle counting, turbidimetry, microscopy, and light scattering – which are suitable for studying the coagulation of latex at very low concentrations, much less work has focused on methods suitable for in-situ characterization of latex coagulation in concentrated solutions (e.g., as relevant to the dipping process). This paper presents a process-relevant rheological protocol for assessing and optimizing latex coagulation dynamics for the thin glove coagulant …

Artificial Intelligence Empowered Biological Research: Paradigm Shifts, Application Scenarios, And Strategic Layout, Xinguang Zhu, Yiming Bao, Zhenong Jin, Xin Li, Sijia Wang, Yueming Wang, Yungui Yang, Cao Xu, Yan Xiong, Bin Han

Bulletin of Chinese Academy of Sciences (Chinese Version)

Life related processes are characterized by high dimensionality and multi-scale properties. Understanding mechanisms underpinning life processes helps promote national healthcare, agricultural development, sustainable ecological civilization, and national security. Current life science research is confronted with an enormous challenge of dimensionality stemming from data explosion and data fragmentation, for which the recent rapid advancement of artificial intelligence (AI) provides novel solutions. AI will catalyze a paradigm shift in life science research from the current experiment based empirical induction to a new closed-loop knowledge acquisition including large scale data collection, model building, model prediction, experimental validation, and iterative of these procedures. Life …

Artificial Intelligence–Driven Paradigm Transformation In Biopharmaceutical R&D: Applications And Emerging Scenarios, Lili Liu, Mingyue Zheng, Ye Yuan, Xutong Li, Rong Fan, Wei Wei, Jinxin Zhao, Guobin Qi, Hua Yue, Likun Gong, Songping Zhang, Jiachen Li, Yuchen Sun, Xiaoyan Chen, Yao Chen, Xin Liu, Xiao Zhang, Yuehong Gao, Jianfeng Li, Kaixian Chen, Guanghui Ma, Jianmin Yue

Bulletin of Chinese Academy of Sciences (Chinese Version)

The biopharmaceutical industry is a critical domain underpinning national scientific and technological innovation development and public health. With the rapid advancement of artificial intelligence (AI) and its deep integration with the life sciences, biomedicine research is undergoing a paradigm shift from traditional experience-driven trial-and-error approaches to data-driven and predictive validation-based models. This study systematically examines the pathways for reshaping research in biomedicine paradigms under the convergence of data-driven, mechanism-driven, and intelligence-driven approaches. It focuses on recent advances in the application of AI across key stages, including drug discovery and design, druggability evaluation, delivery system design and optimization, nonclinical and clinical …

Artificial Intelligence For Science: Connotations, Characteristics, And System, Kaihua Chen, Heyang Li, Hongxin Liu, Binbin Zhao, Shuo Yang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Artificial intelligence is profoundly transforming the fundamental nature of scientific research, reshaping its modes of knowledge production and organizational operation, driving the emergence of a new artificial intelligence for science (AI4S) research paradigm, and accelerating full-chain innovation paradigm transformation. This study defines the basic connotations of AI4S across three dimensions, namely, enabling applications, tools and methods, and epistemic knowledge, and systematically identifies five core characteristics: human-machine symbiosis, autonomous evolution, interdisciplinary integration, resource intensity, and open ecosystems. It further constructs a supporting system and operational architecture encompassing layers of infrastructure, data resources, model tools, task execution, and application scenarios. Building on …

Building Basic Research Ecosystem To Consolidate Foundation Of Strong Nation, Xin Fang, Ke Wen

Bulletin of Chinese Academy of Sciences (Chinese Version)

Basic research is the source of the entire scientific system and the master switch for all technological problems. This study systematically reviews the evolution of the connotation and functions of basic research, and explores the new characteristics of basic research development triggered by the paradigm shift of AI for Science (AI4S): the shift of activity subjects from human‑dominated to human‑machine collaboration, the comprehensive restructuring of organizational models, the increasingly prominent strategic value of public intelligent research infrastructure, and the growing urgency to coordinate security and governance institution building. Addressing the demands of the new era, the study proposes principles and …

Advancing Paradigm Of Quantitative Synthetic Biology And Strengthening Mission-Oriented Basic Research, Chenli Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Synthetic biology is an important frontier in the life sciences, yet its further development remains constrained by limited capacity for rational design. Quantitative synthetic biology, which iteratively integrates quantitative modeling with the construction and analysis of synthetic systems, offers a promising paradigm for addressing this challenge. In this perspective, the study discusses the background and motivations underlying the emergence of this field and summarizes recent developments and exploratory efforts. Considering the unique characteristics of quantitative synthetic biology, it is suggested that progress in the field may benefit from strategically organized collaborative research that balances mission-oriented goals with investigator-driven exploration. On …

Deep Learning Processor: Road To Fundamental Research On Ai Chip, Yunji Chen

Bulletin of Chinese Academy of Sciences (Chinese Version)

Deep learning processor chips serve as an important computation foundation for the artificial intelligence industry, thus has attracted widespread attention from the international communities. The Institute of Computing Technology, Chinese Academy of Sciences took the lead in initiating fundamental research on deep learning processor chips in 2008. At that time, this research direction had not yet entered the mainstream vision of the international communities, with its academic value and development laws yet to gain widespread recognition, and it was confronted with the challenges of three fundamental scientific issues concerning its significance, principle, and architecture.To address the above issues, the research …

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Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Teaching Intercultural Communicative Competence (Icc) At The Afl Novice Level: Teachers’ Practices And Constraints, Nancy Fahmy

Theses and Dissertations

Intercultural Communicative Competence (ICC) is widely recognized as a core objective in language education; however, its implementation in novice-level Arabic as a Foreign Language (AFL) classroom remains insufficiently examined. This study explores what strategies do AFL teachers use to integrate ICC principles at the beginner level (A1–A2), the constraints that shape classroom practice, teachers’ assessment approaches, and perceived professional development needs.

Using an explanatory sequential mixed-methods design, quantitative data were collected through a bilingual (Arabic–English) online survey completed by 54 AFL teachers working across instructional contexts in Egypt, Jordan, the United Kingdom, and the Netherlands. Qualitative data were subsequently gathered …

The Use Of Mobile Applications By Non-Governmental Organizations For Volunteer Recruitment And Retention In Egypt, Mona Sami Morshidy

Theses and Dissertations

Abstract 

Non-governmental organizations (NGOs) have increasingly used digital technology and mobile applications to facilitate volunteerism. In Egypt, mobile applications offer significant opportunities to enhance volunteer management. This study explores how mobile applications and digital platforms facilitate volunteering recruitment and retention in Egypt. The study employs a qualitative research design based on 34 semi-structured interviews with NGO representatives and volunteers with varying years of volunteering experience. The findings highlight the mobile application's effects on recruitment, retention, and management, as well as the challenges of adapting it. The results indicate that NGOs primarily use mobile applications to manage existing volunteers, with only …

Disaster Preparedness, Prevention And Management In Lagos State University Library, Mausi A. Bokoh, Sophia V. Adeyeye Dr, Oluwaseun Adeola Abiodun-Asanre, Mrs

Library Philosophy and Practice (e-journal)

Disasters pose significant threats to human lives, infrastructure, and national socioeconomic development. Effective disaster preparedness, prevention, and management are therefore vital for mitigating their impact and ensuring continuity of operations. This study examined disaster preparedness, prevention, and management practices at Lagos State University Library. A survey research design was adopted, and data were collected through a structured questionnaire covering key aspects of disaster management. Frequency counts, percentages, mean, and standard deviations were used to analyze data.  The findings revealed that the library employs basic preventive strategies such as turning off electricity after work hours and ensuring timely evacuation during emergencies. …

Searches For Continuous Gravitational Waves From Supernova Remnants In The First Part Of The Ligo-Virgo-Kagra Fourth Observing Run, A. G. Abac, I. Abouelfettouh, Teviet Creighton, Mario C. Diaz, Raul Alberto Espinosa Perez, J. Lawrence, Francisco Llamas Villarreal, Soma Mukherjee, Volker Quetschke, Miriam Ramos Arevalo, Wenhui Wang

Physics & Astronomy Faculty Publications

We present results from directed searches for continuous gravitational waves from a sample of 15 nearby supernova remnants, likely hosting young neutron star candidates, using data from the first eight months of the fourth observing run (O4) of the LIGO–Virgo–KAGRA Collaboration. The analysis employs five pipelines: four semicoherent methods—the Band-Sampled-Data directed pipeline, Weave, and two Viterbi pipelines (single- and dual-harmonic)—and PyStoch, a cross-correlation-based pipeline. These searches cover wide frequency bands and do not assume prior knowledge of the targets’ ephemerides. No evidence of a signal is found from any of the 15 sources. We set 95% confidence-level upper limits on …

A Role For The Poly-Asparagine Repeat In The Plasmodium Histone Acetyltransferase, Pfgcn5, Kelly Rubiano, Aaron Morris, Francisca D L Vitorino, Jasper Travis, Benjamin A Garcia, Sumit Mukherjee, Daniel E Goldberg

2020-Current year OA Pubs

Plasmodium falciparum possesses one of the most AT-rich genomes in nature (80.6%). A consequence is an asparagine-rich proteome. A quarter of P. falciparum proteins possess poly-asparagine repeats that can extend more than 100 residues. The role of these repeats has remained a mystery in the biology of this parasite. Here, we report that the poly-asparagine repeat-containing Nterminus of the histone acetyltransferase PfGCN5 associates with the C-terminal catalytic domain after cleavage in the nucleus. Deletion of the repeat destabilizes the N-terminal polypeptide, leading to impaired parasite development and growth, particularly under stress conditions. Using high-resolution mass spectrometry and western blotting analysis, …

Gwtc-4.0: Updating The Gravitational-Wave Transient Catalog With Observations From The First Part Of The Fourth Ligo–Virgo–Kagra Observing Run, A. G. Abac, I. Abouelfettouh, Teviet Creighton, Mario C. Diaz, Raul Alberto Espinosa Perez, J. Lawrence, Francisco Llamas Villarreal, Soma Mukherjee, Volker Quetschke, Miriam Ramos Arevalo, Wenhui Wang

Physics & Astronomy Faculty Publications

Version 4.0 of the Gravitational-Wave Transient Catalog (GWTC-4.0) adds new candidates detected by the LIGO, Virgo, and KAGRA observatories through the first part of the fourth observing run (O4a: 2023 May 24 15:00:00 to 2024 January 16 16:00:00 UTC) and a preceding engineering run. In these new data, we find 128 compact binary coalescence candidates that are identified by at least one of our search algorithms with a probability of astrophysical origin pastro ≥ 0.5 and that are not vetoed during event validation. We also provide detailed source property measurements for 86 of these that have a false-alarm rate …

Fragile Hope And The Cultural Life Of Law, Shefali Jain

Socio-Legal Review

This review of Sandhya Fuchs’ Fragile Hope: Seeking Justice for Hate Crimes in India (Stanford University Press 2024) highlights that the book makes a genuinely original ethnographic and conceptual contribution to caste studies and hate crime scholarship. At the same time, the essay argues that there are three limitations to its framework that require greater engagement: the book’s failure to engage with the legal consciousness tradition in socio-legal scholarship, an underdeveloped account of “legal meliorism,” and an unresolved tension between the book’s stated commitment to victim-centred analysis and its ethnographic evidence that frequently discusses movement-level aspirations.

Air Pollution And Public Health: Global Evidence And Implications, Mohammed Obaid Al-Mansoori

Al-Bahir

Globally, the issue of air pollution keep being one of most serious challenges that affecting environment and human health, coming from emissions of industries, transport, agriculture and also from the fuel people use in homes, in addition to natural events that make the situation worse. This review try to bring together the available evidences about the sources, types, and the health impacts of the main air pollutants, including the gaseous ones like SO₂, O₃, NO₂, and CO, and the particulate matter (PM₁₀, PM₂.₅). Exposure for short or long time to these pollutants is linked with many harmful outcomes, such as …

Investigations On The Effect Of Nano Titanium Oxide On The Properties Of Nickel Alloy Using Powder Metallurgy Technique, Sawsan F. Ahmed, Muaamar A .Kamil

Al-Bahir

Powder metallurgy method was used to prepare nickel-based samples enriched with nano-chromium at a fixed ratio of 5 %wt. Different percentages of nano-titanium oxide were added at (0, 5, 10, 15, 20) %wt. . A 10 mm diameter die was used and the pressing process was carried out with a hydraulic press in one direction at a pressure of 10 tons. The resulting alloys were sintered at 1000°C for two hours. Several tests were performed, including X-ray diffraction of the primary and post-mixed powders, which showed that the nickel was in the FCC (Cubic) system and completely pure, the nano-chromium …

Engineering And Geochemical Assessment Of Grey Clay From Iko Town, South-South Nigeria, For Building Construction Applications, Ubong Williams Robert, Sunday Edet Etuk, Okechukwu Ebuka Agbasi, Grace Peter Umoren

Al-Bahir

Grey clay is abundantly available in Iko Town in South-South Nigeria. However, there is no scientific information on its potentialities. Hence, this research has been designed to determine its suitability for building purpose, considering how necessary shelter is for the survival of man. The flowability, gradation, and geochemistry of the clay were assessed. Also, samples were prepared from the clay under same conditions, dried sufficiently, and then subjected to various tests to examine their heat transfer and strength behaviors. For each test category, ten samples were prepared and used and the data obtained were averaged per test. It was found …

Ucedd Innovations Lead To Idd Networks’ Driving Change: Envision, Empower, Employ, Suzzanne Freeze, Jean Winsor, Brittany M. Powers, Amy Huppi

Developmental Disabilities Network Journal

State systems responsible for administering employment services and supports to people with intellectual and developmental disabilities (IDD) must acclimate to changing demands, address new regulations, and continue to meet needs in an era of high workforce turnover and uncertain funding. While improvements have been made across the U.S., there are still far too many individuals seeking meaningful employment and contributory roles in the community who are not supported to achieve those goals. A key success factor is providing publicly funded state systems with the information needed to strategically pivot toward priorities and ensure smooth transitions of organizational change. Our country’s …

Physical Modeling By Froude Number Similarity Law: Experimental Apparatus For Tests With Offshore Structure Anchors Penetrated With Water Jet, Alana Stern Retzlaff, Adriana Thais Mendes Kich, Caroline Peter, Karina Retzlaff Camargo, Diego De Freitas Fagundes

Seatific Journal

The torpedo pile is a Brazilian technology widely employed for anchoring offshore structures. Studies indicate that the use of vertical water jets applied at the pile tip can increase penetration efficiency and reduce inclination during installation. Considering the high costs and logistical challenges of full-scale testing, investigations using reduced physical models become a viable alternative. This study presents the development and application of an experimental apparatus based on the Froude Number Similarity Law, designed to perform penetration and pullout tests on reduced-scale torpedo pile models without fins, at a 1:76 length scale. To validate the system, an initial series of …

Analysis On Thermo-Viscous Steady Fluid Motion Over An Impermeable Infinitely Stretched Horizontal Moving Rectangular Surface, P. Krishna, N. Pothanna, K. Spandana

Mansoura Engineering Journal

This study presents analysis on thermo-viscous steady fluid motion over an impermeable infinitely stretched horizontal moving rectangular surface. The numerical results have been found employing R-K method of order 6 shooting techniques developed in Mathematica software ND solve for the flow adaptable equations comprising temperature and velocity. The flow behavior and the impacts of material constraints on the flow region have been analyzed and deliberated taking the help from the generated graphs. The variations of these flow fields have been studied for wide spectrum of physical characteristics which influences the nature of thermo-viscous fluid. The impact of viscosity, constant pressure …

Factors Influencing Tourist Interest In Walking Tours In The Kota Tua Area, Novi Handayani, Adrian Hartanto

Journal of Indonesian Tourism and Policy Studies

This study aims to analyze the extent to which the variables of Attraction, Accessibility, Cost and Tarif, Facilities, and Information contribute to Walking tour Interest, both individually (partially) and collectively (simultaneously).  As previous research states that Indonesia has one of the lowest levels of mobility. The average Indonesian walks only 3513 steps per day, while the recommended daily step count for maintaining good health is 5000. This study uses Multiple Linear Regression Analysis as its analysis method using partial hypothesis testing (t-test) and simultaneous hypothesis testing (f-test).. Data were collected through an online questionnaire distributed via Google Form to …

Intermittent Fasting In Chronic Heart Failure: A Systematic Review Of Safety And Physiological Outcomes, Zulrahman Erlangga, Prenali Dwisthi Sattwika

Journal of the Saudi Heart Association

Interest in intermittent fasting has expanded substantially due to its reported metabolic effects. However, whether such dietary patterns are safe for individuals living with chronic heart failure remains unclear. This issue is particularly relevant for patients who fast for religious observance, including Ramadan. We therefore performed a systematic review to evaluate the clinical safety and physiological implications of intermittent fasting in stable heart failure populations. The review protocol adhered to established reporting standards for systematic reviews. Multiple electronic databases were systematically searched from inception through December 2025 to identify studies evaluating intermittent fasting in adults with chronic heart failure. Both …

A Conceptual Model Of The External Costs Of Truck Overloading On Road Damage, Emissions, And Traffic Congestion: A Systematic Literature Review, Aleksius Sitepu, Sutanto Soehodho, Andyka Kusuma

Smart City

Freight transport services cannot be separated from the infrastructure and facilities involved, each of which faces its own challenges in delivering optimal performance in the logistics sector. A common challenge in Indonesia’s road sector is the presence of overloaded freight vehicles, which has become a national issue. This phenomenon has a negative impact not only on road infrastructure but also on the environment and traffic. This study aims to develop a conceptual model of the external costs caused by truck overloading practices in terms of road infrastructure damage, increased exhaust emissions, and traffic congestion through a systematic literature review. This …

Leveraging A Centralized Fleet Assignment Management For An Aviation Resilience, Inof Seno Acton Mr., Sutanto Soehodho, Nahry Yusuf

Smart City

Since deregulation in the aviation industry, competition among airlines has intensified. This competition is shown by the increasing number of routes, service times, aircraft, and airports served. This competition causes not all flight services to meet their targets, resulting in aircraft operating less efficiently. Passenger seats are not filled, and flight delays are becoming more frequent. Obviously, this will negatively impact consumers and the airline's finances. The study focused on assigning the fleet used to serve flights to maintain existing aviation services and improve aircraft operational efficiency. This study aims to maximize profits by optimizing fleet assignments through the Centralized …

Decarbonizing Electrical Substations: An Integrative Review Of Green Technologies And Sustainable Practices Across The Infrastructure Life Cycle, Sulthan Syah Ali, Mohammed Ali Berawi, Mustika Sari

Smart City

Decarbonization of electrical infrastructure s becoming increasingly important in efforts to meet climate change mitigation targets, particularly in reducing emissions from substations. However, conventional substations continue to release significant quantities of GHG emissions throughout their life cycle As an example, a typical 500 kV substation emits around 150,000 tCO2e from construction to decommissioning. In addition, the development of green substation concepts remains limited, particularly in Indonesia where standardized approaches are not yet established. In response to the need for more sustainable power infrastructure, this study aims to identify, classify, and review all types of green technologies, practices, and innovations that …

Optimization Of Sea Transportation Services In The Kepulauan Seribu Using The Vehicle Routing Problem (Vrp) Model, Darmadi Darmadi, Sutanto Soehodho, Nahry Nahry

Smart City

The Kepulauan Seribu regency relies heavily on sea transportation for passenger mobility and goods distribution. However, current systems face efficiency challenges, high operational costs, and potential imbalances between demand and service capacity. This study proposes a framework to optimize sea transportation services in the Kepulauan Seribu using the Vehicle Routing Problem (VRP) method, especially the Capacitated Vehicle Routing Problem – Many Single Depot (CVRP–MSD) model with heterogeneous fleets and mixed cargo (passenger and goods). The main objective is to minimize total operating costs, which include fixed costs of using the vessel and variable travel costs, and unmet demand, both passenger …

Galaxy Morphology Classification Using Deep Learning, Dipanwita Kundu Roy

Master’s Dissertations

Galaxy morphology is the study of the shape and visual appearance of galaxies, such as spiral, smooth, edge-on, and other morphological types. Morphological classification plays an important role in understanding how galaxies form and evolve over cosmic time. Most existing machine learning approaches for galaxy morphology classification rely solely on RGB galaxy images, which primarily capture spatial information and lack the physical spectral context of galaxies. In contrast, astronomical spectral datacubes contain rich information across multiple wavelengths, providing insights into the internal and physical properties of galaxies. However, such spectral observations are available for only a limited number of objects. …

Relay Selection And User Scheduling In Reconfigurable Intelligent Surface Assisted Millimeter-Wave D2d Communication, Lakshmikanta Sau

Doctoral Theses

Reconfigurable intelligent surface (RIS) assisted millimeter wave (mmWave) device to device (D2D) communication has recently been proposed as a viable solution to support the overwhelming data traffic in fifth-generation (5G) and beyond wireless networks. However, due to the substantial propagation and penetration losses of mmWave, a direct line of sight (LoS) link between a pair of proximity devices is required for effective communication. Static obstacles like trees and buildings can easily obstruct the direct LoS connectivity between a device pair. In such cases, RISs help to establish an indirect LoS link between an obstructed device pair by reflecting the signals …