Digital Commons Network^™

South Carolina Teacher Workforce Profile For 2022–23, Brian Cartiff, Svetlana Dmitrieva, Angela Starrett

Reports

SC TEACHER’s research mission includes publishing yearly reports that detail the South Carolina educator workforce, sharing insights with educators themselves, policymakers, community members, and other stakeholders. This report is an annual review of the state's public school teacher workforce.

Analysis in this study uses statewide data from 2022–23, plus available data from published reports, to compare the demographics of South Carolina’s teacher workforce with that of other states and nationwide. This report also provides a longitudinal view of state trends by examining data over three academic years from 2020–21 to 2022–23. Results are based on analysis of data collected from …

Two Essays On Electric Vehicle Subsidies And Auto Industries In China, Jing Liang

Lingnan Theses (MPhil & PhD)

China’s automobile market is the world’s largest automobile market. In recent decades, the development of China’s automobile market has been closely tied to the policies of the Chinese government. This dissertation explores the impact of two key government policies - China’s auto subsidy policy and China’s joint venture policy - on the Chinese automobile market over the past several years. Chapter 1 investigates the pass-through and distributional effects of electric vehicle (EV) subsidies in China. It evaluates how these effects affect market equilibrium and welfare. Empirical results indicate that EV subsidy pass-through to consumers is more than complete, disproportionately favoring …

A Revision Of Hong Kong Harvestmen : Biodiversity, Ecological Preferences And Geographical Distribution, Kai Teck Desmond Tan

Lingnan Theses (MPhil & PhD)

Opiliones, or harvestmen, is a common animal found throughout the world, there are currently over 6,650 species worldwide but the actual number is estimated to exceed 10,000, making it the third largest order in the class Arachnida. Despite its diversity, it is a rather understudied group. In Hong Kong, there are four described species, but the most recent relevant literature dates back to the at least the early 20th century. This thesis focuses on two common species found in Hong Kong: one previously described species (Heterobiantes geniculatus) and one new species (Pseudoleiobunum lutulentum sp. nov.). I …

Fs Agenda 2024-09-04, Northern Illinois University

Faculty Senate Archives

No abstract provided.

Post-Wildfire Water Quality Dynamics: A Multiscale Examination And Predictive Modeling Of Stream Temperature And Turbidity In Western U.S. Watersheds, Junjie Chen

Dissertations and Theses

Wildfires, exacerbated by climate change and human activities, pose significant threats to water-related ecosystem services in forested watersheds. This dissertation investigates the multifaceted impacts of wildfires on stream temperature and turbidity, two critical water quality parameters essential for maintaining aquatic ecosystem health and human water uses. By integrating a comprehensive literature review, empirical data analysis, and advanced machine learning techniques, this research provides a nuanced understanding of how wildfires affect hydrological processes across various temporal and spatial scales.

The findings reveal significant regional variability and the complex interplay between climatic, geographic, and anthropogenic factors. For instance, the literature review highlights …

A Micro-Computed Tomographic Evaluation Of Maxillary First Molar Accessory Root Canal Morphology In A Black South African Subpopulation, Casper Jonker

Peninsula Dental School

PURPOSE: The aim of this study was to investigate the accessory root canal morphology of maxillary first molars in a Black South African subpopulation. METHODS: Micro-computed tomography was used to investigate 101 maxillary first molars (from 50 male and 51 female teeth, right 53 teeth, left 48 teeth). The prevalence of chamber canals, and the number, type and location (root third) of accessory canals were recorded. The relationships between arch side, sex and age were examined using chi-squared tests of association. Intra- and inter-observer reliability were assessed using Cohen's kappa test. RESULTS: Intra- and inter-rater agreement was 96.9% and 98.1%, …

Law School News: Transforming Adversity Into Advocacy 9-4-2024, Andrew Clark, Roger Williams University School Of Law

Life of the Law School (1993- )

No abstract provided.

Intestinal Microbiome As A Diagnostic Marker Of Coronary Artery Disease: A Systematic Review And Meta-Analysis, Yomna E. Dean, Mohamed A. Shebl, Mohamed Doma, Rafeek W. Elmezayen, Jose J. Loayza Pintado, Samah S. Rouzan, Noheir Ashraf Ibrahem Fathy Hassan, Yasmeen E. Yaqout, Akiko Tokunaga, Chukwuebuka Anozie

School of Medicine Publications

Background: The intestinal microbiome has been recently linked to several metabolic and chronic disorders, one of which is coronary artery disease (CAD). Our study aimed to analyze the intestinal microbiome of CAD patients and assess the eligibility of dysbiosis as a diagnostic marker of CAD.

Methods: PubMed, Scopus, Embase, and Web of Science were searched using terms, such as 'CAD' and 'microbiome'. Only observational controlled studies were included. R version 4.2.2 was used for the analysis.

Results: A significant association was found between the CAD group and increased Simpson and Shannon Indices compared with the control group (MD=0.04, 95% CI=0.03-0.05, …

The Prognostic Effect Of Infiltrating Immune Cells Is Shaped By Proximal M2 Macrophages In Lung Adenocarcinoma, Jian-Rong Li, Vikram Shaw, Yupei Lin, Xiang Wang, Muhammad Aminu, Yong Li, Jia Wu, Jianjun Zhang, Christopher I Amos, Chao Cheng

Faculty, Staff and Students Publications

The spatial arrangement of immune cells within the tumor microenvironment (TME) and their interactions play critical roles in the initiation and development of cancer. Several advanced technologies such as imaging mass cytometry (IMC) providing the immunological landscape of the TME with single-cell resolution. In this study, we develop a new method to quantify the spatial proximity between different cell types based on single-cell spatial data. Using this method on IMC data from 416 lung adenocarcinoma patients, we show that the proximity between different cell types is more correlated with patient prognosis compared to the traditional features such immune cell density …

Prospects And Challenges Of Tissue-Derived Extracellular Vesicles, Justin C Lee, Roslyn M Ray, Tristan A Scott

Faculty, Staff and Students Publications

Extracellular vesicles (EVs) are considered a vital component of cell-to-cell communication and represent a new frontier in diagnostics and a means to identify pathways for therapeutic intervention. Recently, studies have revealed the importance of tissue-derived EVs (Ti-EVs), which are EVs present in the interstitial spaces between cells, as they better represent the underlying physiology of complex, multicellular tissue microenvironments in biology and disease. EVs are native, lipid bilayer membraned nano-sized particles produced by all cells that are packaged with varied functional biomolecules including proteins, lipids, and nucleic acids. They are implicated in short- and long-range cellular communication and may elicit …

G Protein Selectivity Profile Of Gpr56/Adgrg1 And Its Effect On Downstream Effectors, Raida Jallouli, Ana L Moreno-Salinas, Andréanne Laniel, Brian Holleran, Charlotte Avet, Joan Jacob, Trang Hoang, Christine Lavoie, Kendra S Carmon, Michel Bouvier, Richard Leduc

Faculty, Staff and Student Publications

GPR56, an adhesion G-protein coupled receptor (aGPCRs) with constitutive and ligand-promoted activity, is involved in many physiological and pathological processes. Whether the receptor's constitutive or ligand-promoted activation occur through the same molecular mechanism, and whether different activation modes lead to functional selectivity between G proteins is unknown. Here we show that GPR56 constitutively activates both G12 and G13. Unlike constitutive activation and activation with 3-α-acetoxydihydrodeoxygedunin (3αDOG), stimulation with an antibody, 10C7, directed against GPR56's extracellular domain (ECD) led to an activation that favors G13 over G12. An autoproteolytically deficient mutant, GPR56-T383A, was also activated by 10C7 indicating that the tethered …

Narrowing The Digital Divide: Framework For Creating Telehealth Equity Dashboards., Michael J. Luke, Sansanee Craig, Suzinne Pak-Gorstein, Marlíse Arellano, Jessica Zhang, Margaret Wright, John Chuo, Philip V. Scribano

Manuscripts, Articles, Book Chapters and Other Papers

Telehealth presents both the potential to improve access to care and to widen the digital divide contributing to health care disparities and obliging health care systems to standardize approaches to measure and display telehealth disparities. Based on a literature review and the operational experience of clinicians, informaticists, and researchers in the Supporting Pediatric Research on Outcomes and Utilization of Telehealth (SPROUT)-Clinical and Translational Science Awards (CTSA) Network, we outline a strategic framework for health systems to develop and optimally use a telehealth equity dashboard through a 3-phased approach of (1) defining data sources and key equity-related metrics of interest; (2) …

Drivers For Design For Deconstruction (Dfd) Implementation Among Design Professionals, H Pittri, K Agyekum, E Botchway, J Alencastro, O Oladinrin, A Dompey

School of Art, Design and Architecture

Purpose- The Design for Deconstruction (DfD) technique, a contemporaneous solution to demolition by optimizing disassembly activities to enable reuse, has recently emerged with several promises to promote the circular economy. However, little attention has been given to its implementation among design professionals, especially in the Global South. Therefore, this study explores the drivers for DfD implementation among design professionals in the Ghanaian construction industry (GCI). Design/methodology/approach- The study adopted a mixed research approach (explanatory sequential design) with an initial quantitative instrument phase, followed by a qualitative data collection phase. Data were analyzed using mean, standard deviation, One-Sample t-Test, and Normalization …

Crizotinib Enhances Parp Inhibitor Efficacy In Ovarian Cancer Cells And Xenograft Models By Inducing Autophagy, Janice M Santiago-O'Farrill, Alicia Blessing Bollu, Hailing Yang, Vivian Orellana, Marc Pina, Xudong Zhang, Jinsong Liu, Robert C Bast, Zhen Lu

Faculty, Staff and Student Publications

Poly (ADP-ribose) polymerase inhibitors (PARPi) can encounter resistance through various mechanisms, limiting their effectiveness. Our recent research showed that PARPi alone can induce drug resistance by promoting autophagy. Moreover, our studies have revealed that anaplastic lymphoma kinase (ALK) plays a role in regulating the survival of ovarian cancer cells undergoing autophagy. Here, we explored whether the ALK-inhibitor crizotinib could enhance the efficacy of PARPi by targeting drug-induced autophagic ovarian cancer cell and xenograft models. Our investigation demonstrates that crizotinib enhances the anti-tumor activity of PARPi across multiple ovarian cancer cells. Combination therapy with crizotinib and olaparib reduced cell viability and …

Successful Treatment Of A Chronic Recurrent Expanding Hematoma Of The Thigh, Gianfranco Galantini, Bakhtawar Mushtaq, Jesse Ottaway, Charles Long

Abington Jefferson Health Papers

Chronic expanding hematoma (CEH) is a rare entity that poses diagnostic and therapeutic challenges due to persistent growth, risk of recurrence, and potential for blood loss anemia. The most common etiologies of CEH are trauma or surgery. It is thought to occur due to irritant effects of blood breakdown products, causing bleeding from capillaries in chronic granulation tissue. Although treatment of CEH is variable, complete surgical excision of the hematoma and its pseudocapsule is the gold standard. We present a case of a 15-year CEH that was initially treated with limited evacuation of the hematoma and cavity decortication, resulting in …

Left Coronary Artery Compression And Stent Fracture Following Self-Expanding Transcatheter Pulmonary Valve Implantation, Jeannette Wong-Siegel, Adam Naylor, David Balzer

2020-Current year OA Pubs

Coronary compression and vascular perforation have not been reported for self-expanding transcatheter pulmonary valves. We describe a patient with tetralogy of Fallot after self-expanding valve implantation who developed left coronary artery compression from the valve. In addition, a wire frame fracture resulted in perforation of the aorta.

A Genetic Screen In Drosophila Uncovers A Role For Senseless-2 In Surface Glia In The Peripheral Nervous System To Regulate Cns Morphology, Haluk Lacin, Yuqing Zhu, Jose T Dipaola, Beth A Wilson, Yi Zhu, James B Skeath

2020-Current year OA Pubs

Despite increasing in mass approximately 100-fold during larval life, the Drosophila CNS maintains its characteristic form. Dynamic interactions between the overlying basement membrane and underlying surface glia are known to regulate CNS structure in Drosophila, but the genes and pathways that establish and maintain CNS morphology during development remain poorly characterized. To identify genes that regulate CNS shape in Drosophila, we conducted an EMS-based, forward genetic screen of the second chromosome, uncovered 50 mutations that disrupt CNS structure, and mapped these alleles to 17 genes. Analysis of whole genome sequencing data wedded to genetic studies uncovered the affected gene for …

A Red Teaming Framework For Securing Ai In Maritime Autonomous Systems, Mathew J. Walter, Aaron Barrett, Kimberly Tam

School of Engineering, Computing and Mathematics

Artificial intelligence (AI) is being ubiquitously adopted to automate processes in science and industry. However, due to its often intricate and opaque nature, AI has been shown to possess inherent vulnerabilities which can be maliciously exploited with adversarial AI, potentially putting AI users and developers at both cyber and physical risk. In addition, there is insufficient comprehension of the real-world effects of adversarial AI and an inadequacy of AI security examinations; therefore, the growing threat landscape is unknown for many AI solutions. To mitigate this issue, we propose one of the first red team frameworks for evaluating the AI security …

Brief Of 15 Scholars Of Law And Medicine As Amici Curiae In Support Of The Petition For Rehearing En Banc, Charles Duan

Amicus Briefs & Court Filings

The panel decision announces an over-expansive, ill-defned doctrine of inducement, in which well-pled allegations may be based on nothing more than ordinary marketing materials and mandatory labeling--even when those materials never recite or describe the claimed invention. This unprecedented and erroneous expansion of inducement liability leaves the law uncertain. It is now unclear, among other things, what statements a generic frm may make about its own product's equivalence and how much of the generic product's labeling information must be revised--assuming that such revisions are even regulatorily allowed--in order to avoid the risk of an inducement lawsuit.

High Impact Malware Targeting Maritime Infrastructure, Kevin Jones, Kimberly Tam

School of Engineering, Computing and Mathematics

Malware, of varying degrees of sophistication, is a growingproblem for any and all computing devices. With computing devices becoming more integrated into daily life across all sectors, malware has amore diverse cyberspace to affect. There is existent research examiningthe problem of malware from various perspectives: Personal Computers, smartphones, Internet of Things devices, etc. The majority of thisresearch has, in the past, focused on Information Technology (IT) devices and IT issues. More recently, there is an emerging body of workwith a focus on Operational Technology (OT), in various domains, suchas power grids, communication infrastructure, and factories. Unlike IT,OT directly monitors and/or …

Interannual Homing To Reproductive Sites And Transboundary Migration In Black Seabream Spondyliosoma Cantharus, With Implications For Management, Peter Davies, Thomas Stamp, Alice Hall, Allison Atterborne, Jen Lewis, George P Balchin, Alice Tebb, Sarah Ward, Francis Binney, Samantha Blampied, Alexander Plaster, Charlie Hubbard, Nick Rogers, Matthew Wiseman, Ronan Conlon, Shion E A Reynell, Emma V Sheehan

School of Biological and Marine Sciences

Fish spawning aggregations are vulnerable to overexploitation, which can have severe ecological, social, and economic consequences. Knowledge on the spatial ecology of aggregating species is often lacking, but is crucial for their effective conservation. This study explores the spawning site residency, interannual fidelity, and migration of black seabream Spondyliosoma cantharus using acoustic (n = 55) and conventional (n = 2397) tagging within and outside Marine Conservation Zones in the southern UK. Detections and recaptures of tagged fish indicated that black seabream display significant interannual fidelity to nesting areas, but that residency of individuals at nesting areas was short relative to …

Interviewing The Interviewers: How Qualitative Professors Assess Interviews In Their Classes, Meredith C. Massey, Leia K. Cain

The Qualitative Report

When reviewing the literature relating to what instructors of qualitative research courses are teaching in their courses, we found a gap regarding qualitative faculty's motivations behind what they teach and whether they use teaching tools such as rubrics in their assessment practices. We utilized general qualitative methods to explore and describe how instructors of qualitative methodology courses conceptualize and design interview-based assessments. By conducting structured interviews with five faculty members, we embraced interpretivist descriptive traditions and sought to obtain thick, rich descriptions of each participant’s perspectives and experiences. After coding interview transcripts, we created themes to represent participant beliefs that …

Caring For Adolescent Learners In The Virtual Classroom: Lessons From The Covid-19 Pandemic, Stephanie Welch, Jeasik Cho

The Qualitative Report

In the recent past, fully online instruction has been most prominent at the higher education level, though online K-12 schools have lately gained some traction. However, the COVID-19 pandemic precipitated new potential for rapid expansion of online K-12 education. As these settings continue to develop, the unique social emotional needs of adolescent learners must be considered, and the need for a robustly developed online pedagogy of care is pressing. An unexpected and untapped resource for developing a framework for an online pedagogy of care can be found in examining the practices of traditionally face-to-face teachers who were unexpectedly thrust into …

Parasitic Contamination Of Soil In The Southern United States, Christine Crudo Blackburn, Sally Mingshuang Yan, David Mccormick, Lauren Nicholas Herrera, Roumen Borilov Iordanov, Mark Daniel Bailey, Maria Elena Bottazzi, Peter J Hotez, Rojelio Mejia

Faculty, Staff and Students Publications

Parasites are generally associated with lower income countries in tropical and subtropical areas. Still, they are also prevalent in low-income communities in the southern United States. Studies characterizing the epidemiology of parasites in the United States are limited, resulting in little comprehensive understanding of the problem. This study investigated the environmental contamination of parasites in the southern United States by determining each parasite's contamination rate and burden in five low-income communities. A total of 499 soil samples of approximately 50 g were collected from public parks and private residences in Alabama, Louisiana, Mississippi, South Carolina, and Texas. A technique using …

Approved Silver Bow Creek Conservation Area Repository Data Gap Quality Assurance Project Plan Request For Change To Install Additional Test Pits And Perform Material Characterization, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Draft Comments On Bpsou “Diggings East 60% Remedial Design Package” Received From British Petroleum - Atlantic Richfield Company (Bp-Ar) On 4/23/2024, Jim Ford

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Preexisting Skin-Resident Cd8 And Γδ T-Cell Circuits Mediate Immune Response In Merkel Cell Carcinoma And Predict Immunotherapy Efficacy, Zachary Z Reinstein, Yue Zhang, Oscar E Ospina, Matt D Nichols, Victoria A Chu, Alvaro De Mingo Pulido, Karol Prieto, Jonathan V Nguyen, Rui Yin, Carlos Moran Segura, Ahmed Usman, Brittney Sell, Spencer Ng, Janis V De La Iglesia, Sunandana Chandra, Jeffrey A Sosman, Raymond J Cho, Jeffrey B Cheng, Ellie Ivanova, Sergei B Koralov, Robbert J C Slebos, Christine H Chung, Nikhil I Khushalani, Jane L Messina, Amod A Sarnaik, Jonathan S Zager, Vernon K Sondak, Charles Vaske, Sungjune Kim, Andrew S Brohl, Xinlei Mi, Brian G Pierce, Xuefeng Wang, Brooke L Fridley, Kenneth Y Tsai, Jaehyuk Choi

Staff and Researcher Publications

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer with a ~50% response rate to immune checkpoint blockade (ICB) therapy. To identify predictive biomarkers, we integrated bulk and single-cell RNA-seq with spatial transcriptomics from a cohort of 186 samples from 116 patients, including bulk RNA-seq from 14 matched pairs pre- and post-ICB. In non-responders, tumors show evidence of increased tumor proliferation, neuronal stem cell markers, and IL-1. Responders have increased type I/II interferons and pre-existing tissue resident (Trm) CD8 or Vδ1 γδ T cells that functionally converge with overlapping antigen-specific transcriptional programs and clonal expansion of public TCRs. Spatial …

Guest Artist Recital: Mark Stevens, Piano, "Scape"; September 4, 2024, Illinois State University School Of Music

School of Music Programs

Center for the Performing Arts

September 4, 2024

Wednesday Evening

7:30 p.m.

From Publius To Santos: Congressional Expulsion And The Enforcement Of Legislative Virtue, Matthew A. Edwards

Emory Law Journal Online

On December 1, 2023, in a historic decision, the U.S. House of Representatives voted to expel Congressperson George Santos. Prior to Santos’s expulsion, only two members of the House had been expelled since the Civil War. In fact, although he was under indictment, Santos was the first member to be expelled from the House without first being convicted of a federal crime or supporting the Confederacy. Santos presented an unusual case, however. By the time that he was expelled, Santos was nationally reviled for fabricating nearly every aspect of his personal biography. Although it is difficult to know what the …

Mrs. Annie Walker Mincey

African American Funeral Programs

Death Notice for Mrs. Annie Walker Mincey at James R. Barnes Mortuary.