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Book Review: A Call To Action: Lessons From Ukraine For The Future Force, John C. Erickson, Timothy S. Martin Oct 2024

Book Review: A Call To Action: Lessons From Ukraine For The Future Force, John C. Erickson, Timothy S. Martin

Parameters Bookshelf – Online Book Reviews

Authors: John A. Nagl and Katie Crombe

Reviewed by John C. Erickson, senior engineer, Axiom Technologies, and Lieutenant Colonel Timothy S. Martin, director, Defense Strategy Course, US Army War College

John C. Erickson and Timothy S. Martin review one of the US Army War College Press’s most-downloaded publications, A Call to Action: Lessons from Ukraine for the Future Force, an integrated research project that covers the first year of the Russia-Ukraine War. Erickson and Martin provide a useful overview and analysis, highlighting 10 key themes, with a special focus on the “Clausewitzian triad” and “mission command,” and explaining why members …


Il-7rα On Cd4+ T Cells Is Required For Their Survival And The Pathogenesis Of Experimental Autoimmune Encephalomyelitis, Gholamreza Azizi, Bram Van Den Broek, Larissa Ishikawa, Hamed Naziri, Reza Yazdani, Guang-Xian Zhang, Bogoljub Ciric, Mohamad Rostami Oct 2024

Il-7rα On Cd4+ T Cells Is Required For Their Survival And The Pathogenesis Of Experimental Autoimmune Encephalomyelitis, Gholamreza Azizi, Bram Van Den Broek, Larissa Ishikawa, Hamed Naziri, Reza Yazdani, Guang-Xian Zhang, Bogoljub Ciric, Mohamad Rostami

Department of Neurology Faculty Papers

BACKGROUND: The IL-7 receptor alpha (IL-7Rα) binds both IL-7 and thymic stromal lymphopoietin (TSLP). IL-7Rα is essential for the development and survival of naive CD4+ T cells and their differentiation to effector/memory CD4+ T cells. Mice lacking IL-7Rα have severe lymphopenia and are resistant to experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis. However, it has been reported that IL-7Rα on peripheral CD4+ T cells is disposable for their maintenance and EAE pathogenesis, which does not align with the body of knowledge on the role of IL-7Rα in the biology of CD4+ T cells. Given that a definitive study …


Principal Perceptions Of The Challenges And Successes Experienced With Teacher Turnover, Elizabeth Anne Thomas Oct 2024

Principal Perceptions Of The Challenges And Successes Experienced With Teacher Turnover, Elizabeth Anne Thomas

Walden Dissertations and Doctoral Studies

Despite interventions to decrease teacher turnover, there remains a 16-24% teacher turnover rate at one Southeastern School District (SSD) in the United States. There is a gap in practice related to the successes and challenges of retaining teachers in the local setting. The purpose of this basic qualitative study was to explore the teacher turnover rates in an SSD that are consistently higher than teacher turnover rates in other state schools and the nation. Lee and Mitchell’s unfolding model of voluntary employee turnover guided this study. Research questions addressed principals' perceptions of the successes and challenges related to the high …


A Qualitative Examination Of Factors Potentially Impacting Displacement Of Historically Black Communities, Daffney Moore Oct 2024

A Qualitative Examination Of Factors Potentially Impacting Displacement Of Historically Black Communities, Daffney Moore

Walden Dissertations and Doctoral Studies

Historically, Black communities have often been discussed in the context of crime and poverty; however, most Black communities were flourishing neighborhoods with businesses, churches, and schools. Most of the literature related to gentrification and displacement does not address the root causes of the disappearance of Black communities, which generally centers on policies, legislation, force-outs, economic development, and racial disparities. This case study aimed to explore the displacement of a suburban historically Black community in St. Louis County, Missouri. Scholars have scarcely examined or written about the history of Black communities. The research question sought to explore the impact of displacement …


The Mediating Role Of Happiness On Marital Satisfaction In Couples Experiencing Mental Health Challenges, Stacey Stafford Oct 2024

The Mediating Role Of Happiness On Marital Satisfaction In Couples Experiencing Mental Health Challenges, Stacey Stafford

Walden Dissertations and Doctoral Studies

While extensive research has examined the impact of mental health challenges on academic and occupational functioning, the effect on marital satisfaction remains underexplored in the literature. Previous studies indicate robust correlations between happiness and mental health, but the specific mediating role of happiness in couples with mental health issues is unaddressed. This archival quantitative study, grounded in Bowen family systems theory, addressed happiness's mediating role on marital satisfaction in couples facing mental health challenges. Using data from the 2018 General Social Survey, this study analyzed a sample of married adults (N = 938) to explore whether happiness mediated the relationship …


Ceo Compensation, Financial Performance, And Donor Contributions In Nonprofit Hospitals, Caprina Poindexter Beal Oct 2024

Ceo Compensation, Financial Performance, And Donor Contributions In Nonprofit Hospitals, Caprina Poindexter Beal

Walden Dissertations and Doctoral Studies

Excessive chief executive offer (CEO) benefits in nonprofit health care organizations can raise ethical concerns when donor funds are diverted from mission-driven programs, potentially diminishing trust among donors and the community. Business leaders need to understand that CEO compensation is a leading indicator of donor investment. Grounded in agency theory, the purpose of this quantitative correlational study was to examine the relationship between CEO compensation, firm performance, and donor contributions. Participants in the study consisted of 110 nonprofit acute care hospitals located in the Southeastern United States. Data were collected from the American Hospital Association’s Annual Survey, National Center for …


Black Clinicians' Perceptions Of The Cultural Relevance Of Parent-Child Interaction Therapy For Black Families, Erica E. Coates, Sierra Coffey, Kaela Farrise Beauvoir, Emily Aron, Katherine R. Hayes, Felipa T. Chavez Oct 2024

Black Clinicians' Perceptions Of The Cultural Relevance Of Parent-Child Interaction Therapy For Black Families, Erica E. Coates, Sierra Coffey, Kaela Farrise Beauvoir, Emily Aron, Katherine R. Hayes, Felipa T. Chavez

Psychology Faculty Publications

Parent–child interaction therapy (PCIT) is a highly efficacious, evidence-based treatment for children with disruptive behaviors and their families. PCIT is a dyadic therapy designed to improve parent–child relationships and decrease children’s behavioral problems. PCIT research specific to Black families is currently sparse. Given findings that Black families have a higher attrition rate and demonstrate fewer significant improvements in parental well-being outcomes, we sought to assess clinicians’ perceived cultural alignment of PCIT with Black families. We conducted individual interviews via Zoom with 10 Black clinicians, trained in PCIT, who had experience treating Black families using PCIT. The research team generated the …


Poverty And Neglect In Child Welfare Law, Laken Albrink, Cameron M. Stamper Oct 2024

Poverty And Neglect In Child Welfare Law, Laken Albrink, Cameron M. Stamper

Justice Festival at Morehead State University

A PowerPoint presentation, titled "Poverty and Neglect in Child Welfare Law," given by Laken Albrink and Cameron M. Stamper at the Justice Festival held on the campus of Morehead State University on October 8, 2024.


2024 Annual Justice Festival Program, Caudill College Of Arts, Humanities, And Social Sciences Oct 2024

2024 Annual Justice Festival Program, Caudill College Of Arts, Humanities, And Social Sciences

Justice Festival at Morehead State University

The program for the 4th Annual Justice Festival held on October 8, 2023 on the campus of Morehead State University.


Challenging Gender Stereotypes: Addressing Misconceptions In Women's Sports, Angel Daugherty, Steve Chen Oct 2024

Challenging Gender Stereotypes: Addressing Misconceptions In Women's Sports, Angel Daugherty, Steve Chen

Justice Festival at Morehead State University

A PowerPoint presentation, titled "Challenging Gender Stereotypes: Addressing Misconceptions in Women's Sports," given by Angel Daugherty and Steve Chen at the Justice Festival held on the campus of Morehead State University on October 8, 2024.


Transition Living Program (Tlp), Kaleb Crenshaw, Monica Himes Oct 2024

Transition Living Program (Tlp), Kaleb Crenshaw, Monica Himes

Justice Festival at Morehead State University

A PowerPoint presentation, titled "Transitional Living Program (TLP)," given by Kaleb Crenshaw and Monica Himes at the Justice Festival held on the campus of Morehead State University on October 8, 2024.


Utopia Exercise Interactive Workshop, Bernadette Barton Oct 2024

Utopia Exercise Interactive Workshop, Bernadette Barton

Justice Festival at Morehead State University

A PowerPoint presentation, titled "Utopia Exercise Interactive Workshop," given by Bernadette Barton at the Justice Festival held on the campus of Morehead State University on October 8, 2024.


A Literature Overview: Ai, Oer, And Implications For Scaling Innovation, Rebecca Mcnulty, Lily Dubach, Sarah A. Norris, Amanda Major Oct 2024

A Literature Overview: Ai, Oer, And Implications For Scaling Innovation, Rebecca Mcnulty, Lily Dubach, Sarah A. Norris, Amanda Major

Faculty Scholarship and Creative Works

Conference Presentation for the 2024 Open Education Conference.

The intersection of artificial intelligence (AI) and open educational resources (OER) holds significant potential for transforming education and scaling innovation. This presentation will offer an overview of the existing scholarly literature to describe the current landscape, including the opinions, opportunities, challenges, risks, and emerging trends. AI can play a pivotal role in enhancing the adoption, adaption, and authorship of OER, both through small experiments and larger theoretical discussions. However, AI also presents challenges and risks, including data privacy concerns, algorithmic bias, and ethical implications, in addition to a broader potential impact on …


Predisposing, Enabling, And Need Factors Influencing Health-Related Quality Of Life Among People With Metabolic Syndrome, Olajide Adekunle, Yun Wang, Ismaeel Yunusa, Marc L. Fleming, Enrique Seoane-Vazquez, Lawrence M. Brown Oct 2024

Predisposing, Enabling, And Need Factors Influencing Health-Related Quality Of Life Among People With Metabolic Syndrome, Olajide Adekunle, Yun Wang, Ismaeel Yunusa, Marc L. Fleming, Enrique Seoane-Vazquez, Lawrence M. Brown

Pharmacy Faculty Articles and Research

Background

Metabolic syndrome (MetS) continues to impact the health-related quality of life (HRQoL) of patients despite various available therapeutic interventions. There is a dearth of information on how patient-centered factors holistically predict HRQoL to provide more insights on addressing MetS.

Objective

To predict the HRQoL of patients with MetS in the Southern states, using the predisposing, enabling, and need factors.

Methods

The study adopted a cross-sectional approach in collecting 706 complete surveys on HRQoL assessment using the EQ-5D-5L survey and demographic characteristics based on the predisposing, enabling, and need factors of Andersen’s Behavioral model. The study focused on people with …


Rapid Unleashing Macrophage Efferocytic Capacity By Transcriptional Pause Release, Turan Tufan Oct 2024

Rapid Unleashing Macrophage Efferocytic Capacity By Transcriptional Pause Release, Turan Tufan

Arts & Sciences Graduate Student Theses and Dissertations

During development, inflammation or tissue injury, macrophages engulf multiple apoptotic cells via efferocytosis to maintain tissue homeostasis. The mechanism by which macrophages rapidly adapt their transcription for continuous corpse uptake is not well understood. Transcriptional pause/release is a conserved mechanism, in which RNA polymerase (Pol) II initiates transcription for 20-60 nucleotides, is paused for minutes to hours and is then released to the elongation phase. We show that macrophages quickly use Pol II pause/release upon encountering corpses to trigger a rapid transcriptional response. This mechanism is essential for continuous efferocytosis but does not affect other forms of phagocytosis. Genomic data …


The Role Of Group 2 Innate Lymphoid Cells In Restoring Lung Health And Chitinase Function After Epithelial Injury, Haerin Jung Oct 2024

The Role Of Group 2 Innate Lymphoid Cells In Restoring Lung Health And Chitinase Function After Epithelial Injury, Haerin Jung

Arts & Sciences Graduate Student Theses and Dissertations

Alveolar epithelial cells provide oxygen transport and act as a first line of defense against pathogens and environmental triggers that disturb tissue homeostasis. However, in the context of epithelial injury, fibrotic and inflammatory lung diseases develop where regenerative responses may become dysregulated or recurrently engaged. One cause of lung injury is infection with cytopathic respiratory viruses such as influenza and SARS-CoV-2 viruses, which induce lung inflammation, tissue damage, and epithelial cell injury and loss. Restoration of barrier integrity after lung injury is critical for re-establishing healthy lung function but the underlying mechanisms are unclear. In the steady state, lung epithelial …


The Role Of Group 2 Innate Lymphoid Cells In Restoring Lung Health And Chitinase Function After Epithelial Injury, Haerin Jung Oct 2024

The Role Of Group 2 Innate Lymphoid Cells In Restoring Lung Health And Chitinase Function After Epithelial Injury, Haerin Jung

Arts & Sciences Graduate Student Theses and Dissertations

Alveolar epithelial cells provide oxygen transport and act as a first line of defense against pathogens and environmental triggers that disturb tissue homeostasis. However, in the context of epithelial injury, fibrotic and inflammatory lung diseases develop where regenerative responses may become dysregulated or recurrently engaged. One cause of lung injury is infection with cytopathic respiratory viruses such as influenza and SARS-CoV-2 viruses, which induce lung inflammation, tissue damage, and epithelial cell injury and loss. Restoration of barrier integrity after lung injury is critical for re-establishing healthy lung function but the underlying mechanisms are unclear. In the steady state, lung epithelial …


Rapid Unleashing Macrophage Efferocytic Capacity By Transcriptional Pause Release, Turan Tufan Oct 2024

Rapid Unleashing Macrophage Efferocytic Capacity By Transcriptional Pause Release, Turan Tufan

Arts & Sciences Graduate Student Theses and Dissertations

During development, inflammation or tissue injury, macrophages engulf multiple apoptotic cells via efferocytosis to maintain tissue homeostasis. The mechanism by which macrophages rapidly adapt their transcription for continuous corpse uptake is not well understood. Transcriptional pause/release is a conserved mechanism, in which RNA polymerase (Pol) II initiates transcription for 20-60 nucleotides, is paused for minutes to hours and is then released to the elongation phase. We show that macrophages quickly use Pol II pause/release upon encountering corpses to trigger a rapid transcriptional response. This mechanism is essential for continuous efferocytosis but does not affect other forms of phagocytosis. Genomic data …


Dean Melanie Leslie’S Office, Benjamin N. Cardozo School Of Law Oct 2024

Dean Melanie Leslie’S Office, Benjamin N. Cardozo School Of Law

2024 Event Invitations

Join Dean Leslie and Professor Zalman Rothschild for a discussion on the First Amendment, anti-discrimination law, and law and religion, as well as any questions raised by student attendees.


مدى مساهمة الهندسة البشرية الخضراء في خفض مستويات الاصابة بالأمراض المهنية: دراسة ميدانية في عدد من المصانع في محافظة نينوى, رياض جميل وهاب, عمر سعيد عبد الله Oct 2024

مدى مساهمة الهندسة البشرية الخضراء في خفض مستويات الاصابة بالأمراض المهنية: دراسة ميدانية في عدد من المصانع في محافظة نينوى, رياض جميل وهاب, عمر سعيد عبد الله

Muthanna Journal of Administrative and Economics Sciences

يسعى البحث الى قياس وتحديد مستوى مساهمة الهندسة البشرية الخضراء في خفض مستويات الاصابة بالأمراض المهنية وبالتالي انعكاس ذلك عل تحسين اداء العاملين وارتفاع الانتاجية ورفع الروح المعنوية للأفراد العاملين في بيئية العمل . يمكن تمثيل مشكلة البحث بانه ( بيئة العمل تعاني من ضعف الانتاجية نتيجة استخدام الوسائل والادوات التقليدية ذات الاثر السلبي على صحة وسلامة الافراد العاملين في الميدان المبحوث) ولغرض معالجة المشكلة المطروحة تم اختيار مدخل الهندسة البشرية الخضراء لتجاوز نقاط الضعف في المستلزمات المادية المستخدمة في بيئة العمل .وتم الاعتماد على الاستبانة كأداة رئيسية للحصول على البيانات من الميدان المبحوث ، تمثل عينة البحث بالأفراد العاملين …


Understanding Emotional Outbursts: A Cross-Cultural Study In Latin American Children With Autism Spectrum Disorder, Maria Cristina Triguero Veloz Teixeira, Rosane Lowenthal, Alexia Rattazzi, Sebastián Cukier, Daniel Valdez, Ricardo Garcia, Gabriela Garrido Candela, Analia Rosoli Murillo, Francislene Pereira Da Silva Leite, Cecilia Montiel-Nava Oct 2024

Understanding Emotional Outbursts: A Cross-Cultural Study In Latin American Children With Autism Spectrum Disorder, Maria Cristina Triguero Veloz Teixeira, Rosane Lowenthal, Alexia Rattazzi, Sebastián Cukier, Daniel Valdez, Ricardo Garcia, Gabriela Garrido Candela, Analia Rosoli Murillo, Francislene Pereira Da Silva Leite, Cecilia Montiel-Nava

Psychological Science Faculty Publications

Objectives: One of the behavioral problems strongly associated with emotional dysregulation (ED) in ASD is emotional outbursts (EOs) characterized by a pattern of challenging behavior that varies across individuals and across time. Cultural factors can modulate the expression of EOs. This study aimed to characterize the profile of emotional outbursts (EOs) in children with autism spectrum disorder (ASD) across various countries in Latin America and to identify clinical, emotional, and contextual factors that contribute to the onset and frequency of EOs within this diverse sample. Methods: A cross-sectional and cross-cultural study was conducted between 2023 and 2024 comprising samples from …


Closed-Loop Adaptive Optics In The Presence Of Speckle And Weak Scintillation, Derek J. Burrell, Mark F. Spencer, Ronald G. Driggers Oct 2024

Closed-Loop Adaptive Optics In The Presence Of Speckle And Weak Scintillation, Derek J. Burrell, Mark F. Spencer, Ronald G. Driggers

Faculty Publications

In this paper, we show that speckle averaging helps to improve adaptive-optics (AO) performance in closed loop as a result of reduced measurement error associated with a Shack–Hartmann wavefront sensor (SHWFS); however, this reduction is rendered ineffective with increasing beacon anisoplanatism. We do so operating in a weak-scintillation regime, where the SHWFS offers robust performance, and using in-plane translation of the illuminated rough surface to accomplish frame-to-frame speckle diversity. Understanding these trade-space limitations is critical when performing AO with non-cooperative, extended-source beacons.


Challenges And Future Directions In Quantifying Terrestrial Evapotranspiration, Koong Yi, Gabriel B. Senay, Joshua B. Fisher, Lixin Wang, Kosana Suvočarev, Housen Chu, Georgianne W. Moore, Kimberly A. Novick, Mallory L. Barnes, Trevor F. Keenan, Kanishka Mallick, Xiangzhong Luo, Justine E. C. Missik, Kyle B. Delwiche, Jacob A. Nelson, Stephen P. Good, Xiangming Xiao, Steven A. Kannenberg, Arman Ahmadi, Tianxin Wang, Gil Bohrer, Marcy E. Litvak, David E. Reed, A. Christopher Oishi, Margaret S. Torn, Dennis Baldocchi Oct 2024

Challenges And Future Directions In Quantifying Terrestrial Evapotranspiration, Koong Yi, Gabriel B. Senay, Joshua B. Fisher, Lixin Wang, Kosana Suvočarev, Housen Chu, Georgianne W. Moore, Kimberly A. Novick, Mallory L. Barnes, Trevor F. Keenan, Kanishka Mallick, Xiangzhong Luo, Justine E. C. Missik, Kyle B. Delwiche, Jacob A. Nelson, Stephen P. Good, Xiangming Xiao, Steven A. Kannenberg, Arman Ahmadi, Tianxin Wang, Gil Bohrer, Marcy E. Litvak, David E. Reed, A. Christopher Oishi, Margaret S. Torn, Dennis Baldocchi

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Terrestrial evapotranspiration is the second-largest component of the land water cycle, linking the water, energy, and carbon cycles and influencing the productivity and health of ecosystems. The dynamics of ET across a spectrum of spatiotemporal scales and their controls remain an active focus of research across different science disciplines. Here, we provide an overview of the current state of ET science across in situ measurements, partitioning of ET, and remote sensing, and discuss how different approaches complement one another based on their advantages and shortcomings. We aim to facilitate collaboration among a cross-disciplinary group of ET scientists to overcome the …


2024 Annual Flu Shot And Covid-19 Vaccine Event, New York Law School Oct 2024

2024 Annual Flu Shot And Covid-19 Vaccine Event, New York Law School

Miscellaneous Campus Flyers

October 8, 2024

October 16, 2024


Aspect-Ratio-Dependent Heat Transport By Baroclinic Acoustic Streaming, Jacques Abdul Massih, Remil Mushthaq, Guillaume Michel, Gregory P. Chini Oct 2024

Aspect-Ratio-Dependent Heat Transport By Baroclinic Acoustic Streaming, Jacques Abdul Massih, Remil Mushthaq, Guillaume Michel, Gregory P. Chini

Faculty Publications

Standing acoustic waves have been known to generate Eulerian time-mean ‘streaming’ flows at least since the seminal investigation of Lord Rayleigh in the 1880s. Nevertheless, a recent body of numerical and experimental evidence has shown that inhomogeneities in the ambient density distribution lead to much faster flows than arise in classical Rayleigh streaming. The emergence of these unusually strong flows creates new opportunities to enhance heat transfer in systems in which convective cooling cannot otherwise be easily achieved. To assess this possibility, a theoretical study of acoustic streaming in an ideal gas confined in a rectangular channel with top and …


Impact Of Cancer Therapy On Clonal Hematopoiesis Mutations And Subsequent Clinical Outcomes, Kevin T Nead, Taebeom Kim, Lijin Joo, Tina L Mcdowell, Justin W Wong, Elizabeth Brock, Ting Xu, Chad Tang, Chang-Lung Lee, Jun-Ichi Abe, Kelly L Bolton, Zhongxing Liao, Paul A Scheet, Steven H Lin Oct 2024

Impact Of Cancer Therapy On Clonal Hematopoiesis Mutations And Subsequent Clinical Outcomes, Kevin T Nead, Taebeom Kim, Lijin Joo, Tina L Mcdowell, Justin W Wong, Elizabeth Brock, Ting Xu, Chad Tang, Chang-Lung Lee, Jun-Ichi Abe, Kelly L Bolton, Zhongxing Liao, Paul A Scheet, Steven H Lin

Faculty, Staff and Student Publications

Exposure to cancer therapies is associated with an increased risk of clonal hematopoiesis (CH). The objective of our study was to investigate the genesis and evolution of CH after cancer therapy. In this prospective study, we undertook error-corrected duplex DNA sequencing in blood samples collected before and at 2 time points after chemoradiation in patients with esophageal or lung cancer recruited from 2013 to 2018. We applied a customized workflow to identify the earliest changes in CH mutation count and clone size and determine their association with clinical outcomes. Our study included 29 patients (87 samples). Their median age was …


Fast, Variable Stiffness-Induced Braided Coiled Artificial Muscles, Xinghao Hu, Xiangyu Wang, Jian Wang, Guorong Zhang, Shaoli Fang, Ye Xiao, Ray H Baughman, Jianning Ding Oct 2024

Fast, Variable Stiffness-Induced Braided Coiled Artificial Muscles, Xinghao Hu, Xiangyu Wang, Jian Wang, Guorong Zhang, Shaoli Fang, Ye Xiao, Ray H Baughman, Jianning Ding

Faculty, Staff and Student Publications

Biomimetic actuation technologies with high muscle strokes, cycle rates, and work capacities are necessary for robotic systems. We present a muscle type that operates based on changes in muscle stiffness caused by volume expansion. This muscle is created by coiling a mechanically strong braid, in which an elastomer hollow tube is adhesively attached inside. We show that the muscle reversibly contracts by 47.3% when driven by an oscillating input air pressure of 120 kilopascals at 10 Hz. It generates a maximum power density of 3.0 W/g and demonstrates a mechanical contractile efficiency of 74%. The muscle's low-pressure operation allowed for …


Rapid Hyperspectral Photothermal Mid-Infrared Spectroscopic Imaging From Sparse Data For Gynecologic Cancer Tissue Subtyping, Reza Reihanisaransari, Chalapathi Charan Gajjela, Xinyu Wu, Ragib Ishrak, Sara Corvigno, Jinsong Liu, David Mayerich, Sebastian Berisha, Rohith Reddy Oct 2024

Rapid Hyperspectral Photothermal Mid-Infrared Spectroscopic Imaging From Sparse Data For Gynecologic Cancer Tissue Subtyping, Reza Reihanisaransari, Chalapathi Charan Gajjela, Xinyu Wu, Ragib Ishrak, Sara Corvigno, Jinsong Liu, David Mayerich, Sebastian Berisha, Rohith Reddy

Faculty, Staff and Student Publications

Ovarian cancer detection has traditionally relied on a multistep process that includes biopsy, tissue staining, and morphological analysis by experienced pathologists. While widely practiced, this conventional approach suffers from several drawbacks: it is qualitative, time-intensive, and heavily dependent on the quality of staining. Mid-infrared (MIR) hyperspectral photothermal imaging is a label-free, biochemically quantitative technology that, when combined with machine learning algorithms, can eliminate the need for staining and provide quantitative results comparable to traditional histology. However, this technology is slow. This work presents a novel approach to MIR photothermal imaging that enhances its speed by an order of magnitude. This …


Ct Strain Metrics Allow For Earlier Diagnosis Of Bronchiolitis Obliterans Syndrome After Hematopoietic Cell Transplant, Husham Sharifi, Christopher D Bertini, Mansour Alkhunaizi, Maria Hernandez, Zayan Musa, Ihsan Turk, Burton F Dickey, Guang-Shing Cheng, Gregory Yanik, Craig J Galban, Huawei Henry Guo, Myrna C B Godoy, Joseph M Reinhardt, Eric A Hoffman, Mario Castro, Gabriela Rondon, Amin M Alousi, Richard E Champlin, Elizabeth J Shpall, Ying Lu, Samuel Peterson, Keshav Datta, Mark R Nicolls, Joe Hsu, Ajay Sheshadri Oct 2024

Ct Strain Metrics Allow For Earlier Diagnosis Of Bronchiolitis Obliterans Syndrome After Hematopoietic Cell Transplant, Husham Sharifi, Christopher D Bertini, Mansour Alkhunaizi, Maria Hernandez, Zayan Musa, Ihsan Turk, Burton F Dickey, Guang-Shing Cheng, Gregory Yanik, Craig J Galban, Huawei Henry Guo, Myrna C B Godoy, Joseph M Reinhardt, Eric A Hoffman, Mario Castro, Gabriela Rondon, Amin M Alousi, Richard E Champlin, Elizabeth J Shpall, Ying Lu, Samuel Peterson, Keshav Datta, Mark R Nicolls, Joe Hsu, Ajay Sheshadri

Faculty, Staff and Student Publications

Bronchiolitis obliterans syndrome (BOS) after hematopoietic cell transplantation (HCT) is associated with substantial morbidity and mortality. Quantitative computed tomography (qCT) can help diagnose advanced BOS meeting National Institutes of Health (NIH) criteria (NIH-BOS) but has not been used to diagnose early, often asymptomatic BOS (early BOS), limiting the potential for early intervention and improved outcomes. Using pulmonary function tests (PFTs) to define NIH-BOS, early BOS, and mixed BOS (NIH-BOS with restrictive lung disease) in patients from 2 large cancer centers, we applied qCT to identify early BOS and distinguish between types of BOS. Patients with transient impairment or healthy lungs …


The Impact Of A Web-Based Prognostic Calculator On Prognostic Confidence In Outpatient Palliative Care, David Hui, John P Maxwell, Allison De La Rosa, Kristofer Jennings, Marieberta Vidal, Ahsan Azhar, Kimberson Tanco, Yvonne Heung, Marvin Delgado-Guay, Donna Zhukovsky, Joseph Arthur, Suresh Reddy, Sriram Yennu, Amy Ontai, Eduardo Bruera Oct 2024

The Impact Of A Web-Based Prognostic Calculator On Prognostic Confidence In Outpatient Palliative Care, David Hui, John P Maxwell, Allison De La Rosa, Kristofer Jennings, Marieberta Vidal, Ahsan Azhar, Kimberson Tanco, Yvonne Heung, Marvin Delgado-Guay, Donna Zhukovsky, Joseph Arthur, Suresh Reddy, Sriram Yennu, Amy Ontai, Eduardo Bruera

Faculty, Staff and Student Publications

Purpose: Clinicians are often uncertain about their prognostic estimates, which may impede prognostic communication and clinical decision-making. We assessed the impact of a web-based prognostic calculator on physicians' prognostic confidence.

Methods: In this prospective study, palliative care physicians estimated the prognosis of patients with advanced cancer in an outpatient clinic using the temporal, surprise, and probabilistic approaches for 6 m, 3 m, 2 m, 1 m, 2 w, 1 w, and 3 d. They then reviewed information from www.predictsurvival.com , which calculated survival estimates from seven validated prognostic scores, including the Palliative Prognostic Score, Palliative Prognostic Index, and Palliative Performance …