Digital Commons Network^™

Personalized Brachytherapy: Applications And Future Directions, Chengfeng Li, Bin S Teh, Edward B Butler, Andrew M Farach

Faculty, Staff and Students Publications

Brachytherapy offers a highly conformal and adaptive approach to radiation therapy for various oncologic conditions. This review explores the rationale, applications, technological advances, and future directions of personalized brachytherapy. Integration of advanced imaging techniques, 3D-printed applicators, and artificial intelligence are rapidly enhancing brachytherapy delivery and efficiency, while genomic tests and molecular biomarkers are refining patient and dose selection. Emerging research on combining brachytherapy with immunotherapy offers unique synergistic potential, and technologies such as intensity-modulated and shielded brachytherapy applicators present novel opportunities to further optimize dose distributions. Despite these promising advances, the field faces challenges including a need to train more …

Effective Corporate Social Responsibility And Environmental, Social, And Governance Incorporation Strategies, Dorathy Okeke-Okiche

Walden Dissertations and Doctoral Studies

Failure to develop and implement effective strategies for integrating corporate social responsibility (CSR) and environmental, social, and governance (ESG) initiatives to manage economic risks can lead to reputational damage and hinder the ability to attract investors, customers, and talent. Organizational leaders of small and medium-sized enterprises (SMEs) need to adopt effective strategies to incorporate CSR and ESG initiatives to mitigate economic risks. Grounded in stakeholder theory and triple bottom line framework, the purpose of this qualitative pragmatic inquiry study was to explore the effective strategies employed by business leaders of SMEs to incorporate CSR and ESG initiatives for managing economic …

Rare Variant Contribution To The Heritability Of Coronary Artery Disease, Ghislain Rocheleau, Erica P Young, Nathan O Stitziel, Et Al.

2020-Current year OA Pubs

Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to WGS of 4949 cases and 17,494 controls of European ancestry from the NHLBI TOPMed program. We estimate CAD heritability at 34.3% assuming a prevalence of 8.2%. Ultra-rare (minor allele frequency ≤ 0.1%) variants with low linkage disequilibrium (LD) score contribute ~50% of the heritability. We also investigate CAD heritability enrichment using a diverse set of functional annotations: i) constraint; ii) predicted protein-altering impact; iii) cis-regulatory elements from a cell-specific chromatin …

Clinical Sequelae Of Gut Microbiome Development And Disruption In Hospitalized Preterm Infants, Robert Thänert, Drew J Schwartz, Eric C Keen, Carla Hall-Moore, Bin Wang, Nurmohammad Shaikh, Jie Ning, L Colleen Rouggly-Nickless, Anna Thänert, Aura Ferreiro, Skye R S Fishbein, Janice E Sullivan, Paula Radmacher, Marilyn Escobedo, Barbara B Warner, Phillip I Tarr, Gautam Dantas

2020-Current year OA Pubs

Aberrant preterm infant gut microbiota assembly predisposes to early-life disorders and persistent health problems. Here, we characterize gut microbiome dynamics over the first 3 months of life in 236 preterm infants hospitalized in three neonatal intensive care units using shotgun metagenomics of 2,512 stools and metatranscriptomics of 1,381 stools. Strain tracking, taxonomic and functional profiling, and comprehensive clinical metadata identify Enterobacteriaceae, enterococci, and staphylococci as primarily exploiting available niches to populate the gut microbiome. Clostridioides difficile lineages persist between individuals in single centers, and Staphylococcus epidermidis lineages persist within and, unexpectedly, between centers. Collectively, antibiotic and non-antibiotic medications influence gut …

A Review Of Biomass-Based Natural Coagulants For Water Pollution Remediation: Impact Of Properties And Coagulation Operational Parameters, Nur Faizzah Husna Mohammad Ali, Megat Ahmad Kamal Megat Hanafiah, Sabiha Hanim Saleh, Mohd Tajudin Mohd Ali, Shariff Ibrahim

AUIQ Complementary Biological System

The rapid growth of cities, industries, and population has made tackling water scarcity increasingly challenging as the global demand for clean drinking water continues to rise. Consequently, extensive research in water and wastewater treatment, specifically focusing on the coagulation process, has ensued. Coagulation plays a critical role in water treatment, and its effectiveness depends on the type of coagulant used. However, the widespread use of chemical coagulants raises concerns for the environment and public health. Consequently, there has been growing interest in exploring natural alternatives derived from plants and animals. This review examines how the properties of natural coagulants, as …

On-Pixel Ratio-Based Adjustment Of Local High Brightness Control, Xiaoping Bai, Vicky Wen

Defensive Publications Series

This publication describes systems and techniques to adjust a local high brightness mode (LHBM) of a portion of a touch-screen display responsive to an on-pixel ratio (OPR) of the display. In some aspects, the display driver may determine a current OPR range of one or more OPR ranges that includes the display OPR and then alter the LHBM brightness by a predetermined adjustment factor associated with the current OPR range. Adjustment of the LHBM brightness according to one or more adjustment factors allows the LHBM to provide adequate illumination for fingerprint authentication at different OPRs to maintain a low fingerprint …

Crafting Lornoxicam-Infused Microsponges For Elevated Efficacy In Inflammatory Disorders, Vishal Yadav, Pooja Kachare

Bulletin of Faculty of Pharmacy Cairo University

Introduction: Lornoxicam (LRX), a member of the Oxicam class of non-steroidal anti-inflammatory drugs (NSAIDs), exhibits potent analgesic, anti-inflammatory, and antipyretic properties. Nevertheless, its effectiveness is hampered by high dosage requirements, a short half-life, and low and pH dependent water solubility, necessitating further research for enhanced therapeutic outcomes.

Methodology: This study introduces floating microsponges of LRX to enhance drug release duration and reduce dosing frequency. Microsponges were formulated using quasi-emulsion solvent diffusion with ethyl cellulose and polyvinyl alcohol (PVA) as sustained-release polymers. A 3² factorial design assessed the effects of ethyl cellulose (X₁) and PVA (X₂) …

Tolkien And The Kalevala (2024) By Jyrki Korpua, Translated By Sonja Virta, Verlyn Flieger

Journal of Tolkien Research

Book review, by Verlyn Flieger, of Tolkien and the Kalevala (2024) by Jyrki Korpua.

Vol. 28, No. 12 - Whole No. 138, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 11 - Whole No. 137, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 10 - Whole No. 136, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 9 - Whole No. 135, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 8 - Whole No. 134, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 7 - Whole No. 133, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 6 - Whole No. 132, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 5 - Whole No. 131, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 4 - Whole No. 130, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 3 - Whole No. 129, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 2 - Whole No. 128, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 28, No. 1 - Whole No. 127, David Bratman

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Mutations And Antibiotic Resistance In Mycobacterium Tuberculosis, Ryan M. Johnson, Bodhi Brady, Nicklaus Busse, Connor Beckman, Hunter Gloden, Joseph Glasrud, Zachary Smith, Hari P. Nepal, Madhav P. Nepal

Life Science Reports

Mycobacterium tuberculosis (MTB) is a bacterium known to target, infect, and destroy lung cells as well as connective tissues within the body. This bacterium is prevalent worldwide and has infected over a quarter of the current world population, becoming one of the most successful pathogens in history. Due to its extreme transmission rates as an airborne pathogen, MTB strains have been treated with antibiotics such as rifampicin and isoniazid, which inhibit bacterial infection in the human body. These first-round drugs remained as successful mechanisms for slowing and killing the pathogen, notably through rifampicin's inhibition of RNA-polymerase and isoniazid’s ability to …

Prescription Adherence Rates Across Medication Categories, Makenzie Stagner, Allie Weber, Madhav P. Nepal, Hari P. Nepal

Life Science Reports

Prescription adherence is a major public health challenge, as non-adherence to medication instructions can lead to poorer health outcomes and higher healthcare costs. Although prescription adherence is crucial for managing patient compliance and health outcomes, adherence rates differ greatly between medication types. The main objectives of this study were to determine prescription adherence rates across six medication types (antibiotic, cardiac, chronic health, pediatric, and psychiatric) and identify sources of variation. We searched PubMed and Web of Science databases for relevant published articles. Previous research data were selected related to prescription adherences and compliance rates were included in our analysis. Results …

Applications Of Microlearning Tools And Platforms, Joel Reynolds, Mary Jo Dolasinski

ICHRIE Research Reports

Microlearning has emerged as a solution, offering a flexible and individualized learning structure. This study assessed microlearning authoring tools and delivery technologies to evaluate their suitability for higher education. The analysis identified Vimeo as a leading choice for video and audio content, Vista Create and Adobe Express for visual content, ChatGPT for text-based content, and Adobe Creative Cloud and Microsoft Office for comprehensive use. 7Taps emerged as a top microlearning platform due to its robust features and AI assistance.

Microlearning’s flexibility and adaptability make it valuable for industries like hospitality, which require dynamic training solutions. By selecting the right tools, …

Post-Pandemic Predictors Of Anxiety In College Students, Lisa J. Hayes, R. Brooke Bays, Piper Lashley, Nia Kherani, Alex Swanson

Journal of Applied Disciplines

Rates of anxiety among college students have increased significantly during the COVID-19 pandemic and have remained high (Elharake et al., 2023), placing students at risk for diminished academic performance, depression, and academic burnout (Rassaby et al., 2022). The goal of this study was to examine possible predictors of anxiety in a diverse group of undergraduate students post-pandemic, with the goal of informing future preventive intervention efforts. Maladaptive perfectionism, passive procrastination, active procrastination, cognitive flexibility, and social well-being were assessed as potential predictors of state and trait anxiety in a sample of 297 currently enrolled college students. Results showed that perfectionism …

Carrying The Weight Of Pregnancy Anxiety, Danielle Yates

Family Perspectives

No abstract provided.

Fostering Healthy Sexuality In The Emerging Generation: Reminders For Latter-Day Saints, Melina Myers

Family Perspectives

No abstract provided.

Family Meals: Expectation Vs. Reality, Lindsey Hair

Family Perspectives

No abstract provided.

How Parent-Child Attachment May Influence Relational Self-Efficacy In Adults, Rachel Abraham

Family Perspectives

No abstract provided.

Dollars And Daddy Issues: The Effect Of Parental Gambling On Children’S Attachment Style And Relational Outcomes, Mackenzie Pistritto

Family Perspectives

No abstract provided.

Viewing Adhd’S Impact On Children’S Social Development Through The Lens Of Peer Rejection, Bethany Sycamore

Family Perspectives

No abstract provided.