Digital Commons Network^™

Inference In A Stationary/Nonstationary Autoregressive Time-Varying-Parameter Model, Donald W.K. Andrews, Ming Li

Cowles Foundation Discussion Papers

This paper considers nonparametric estimation and inference in first-order autoregressive (AR(1)) models with deterministically time-varying parameters. A key feature of the proposed approach is to allow for time-varying stationarity in some time periods, time-varying nonstationarity (i.e., unit root or local-to-unit root behavior) in other periods, and smooth transitions between the two. The estimation of the AR parameter at any time point is based on a local least squares regression method, where the relevant initial condition is endogenous. We obtain limit distributions for the AR parameter estimator and t-statistic at a given point τ in time when the parameter exhibits unit …

Bargaining For Justice: Ukraine, Gaza, And The Ethics Of Conflict Termination, C. Anthony Pfaff

Books, Monographs & Collaborative Studies

©2024 C. Anthony Pfaff

As wars in Ukraine and Gaza continue with little end in sight, the sense of urgency to determine how they should end is increasing, given how the wars could end. A just war aims to establish a better state of peace, but a better state of peace may not always be achievable, and even when it is achievable, it may not be good enough. When that is the case, actors must determine on what terms to settle, given what they think they can achieve based on relative capabilities and cost tolerances. The resulting “maximin” solution, a …

The Power Of Homeownership: The Case For Iowa Heartland Habitat For Humanity, Esha Jayswal, Joseph Ugrin, Disa Cornish, Brent Buhr, Ali Parrish

Faculty Publications

This research examines the impact of financially assisted homeownership for Iowa Heartland Habitat for Humanity home recipients as measured in life satisfaction. We develop and assess a model with homeownership as the independent variable and financial well-being, current health, and psychological well-being as mediating variables that impact life satisfaction. We utilize data from 184 Iowa Heartland Habitat for Humanity homeowners and applicants to test the model. The findings show that homeownership through Iowa Heartland Habitat for Humanity is related to life satisfaction. That relationship is partially mediated by financial well-being, current health, and psychological well-being, where the mediating variables amplify …

Tooth Type And Position In A Hypothetical Pectinodon..., Keith Snyder, Jonathon Campos, Neal Doran, Charity Simmons

Achieve

In 1856, Leidy rst identied Troodontidae as a taxonomic unit. It was not until 1945 that C.M. Sternberg assigned it to a family status. There has been much debate on taxonomic naming in this family, but in 1987, Currie conated all previous names into a single species, Troodon formosus. On the basis of isolated teeth, Carpenter (1982) suggested a second species, Pectinodon bakkeri from the Lance Formations. With limited specimens (24), Longrich (2008) proposed tooth positioning for the 4 tooth types he dened. This was especially challenging since no cranial or post-cranial skeletal structures have yet been identied.

Over the …

1719 Gates Llc V. Torres

All Decisions

The landlord initiated a holdover proceeding against the tenant seeking to recover the premises based on the expiration and non-renewal of the tenant's lease. The landlord argued that the tenant owed rent arrears and that this constituted a "good cause" for eviction under the Good Cause Eviction Law (GCEL). However, the court dismissed the petition, finding that GCEL does not allow a holdover based solely on a tenant owing rent arrears and that the landlord's legal remedy is to commence a nonpayment proceeding. The court emphasized that the legislature intended to impose additional conditions to evict tenants covered by GCEL …

120e62 Realty Llc. V. Doe

All Decisions

Landlord made a post-discontinuance motion to change name on money judgment from Jane Doe to Respondent's legal name. Motion denied on the basis that the prior discontinuance of the case deprived the court of jurisdiction.

Warming And Nitrogen Enrichment Lead To Surprising Soil Carbon Dynamics, Nicholas Gosling

UNH Today Archive

No abstract provided.

Breaking The Code: Impact Of Educational Escape Room On Students’ Knowledge And Perception Of Ethics And Legislation In Pharmacy, Janet, Sui Ling Tan, Adnan Siti Nur Maisarah, A Ham Suri Nor Syahira

Research Publications (2021 to 2025)

Pharmacy education has evolved significantly to meet the dynamic demands of the healthcare industry, requiring students to possess a broad range of knowledge and skills. Ethics and legislation are crucial aspects of this profession but often challenge student engagement and motivation. In response, we developed an escape room tailored to the Ethics and Legislation course in the Pharmacy programme. This study aims to evaluate the impact of this educational escape room on the knowledge and perceptions of third-year pharmacy students. The escape room involved puzzles focused on various Acts and Regulations in Pharmacy and its effectiveness was evaluated through pre-and …

Effects Of Microplastic Biofilms On An Anthropogenically Impacted Suburban Lake, Paris M. Velasquez

Masters Theses

Plastics have been observed in every location on the planet, and their prevalence in the environment is due in part to their strong resistance to degradation. Inland lakes are susceptible to plastic pollution by highway runoff, which contains plastic fragments of brake pads, car tires, litter, and road paint. These plastics eventually enter freshwater environments and degrade into microplastics (

Nevada’S Housing Policy Landscape: Data, Analysis, And Policy Solutions, Brookings Mountain West, Lied Center For Real Estate

Brookings Mountain West Special Events

From rising rents to high interest rates to limited supply, housing policy is a central issue in the 2024 elections. Brookings Mountain West, in partnership with UNLV’s Lied Center for Real Estate, hosted a community forum examining the local, state, and federal impacts of Nevada’s housing challenges. New research presented at the forum offer insights into the demographic and economic dynamics of individuals and families navigating Nevada's turbulent housing market, assess trends in home ownership, and evaluate barriers preventing Nevadans from accessing the housing market.

A Delphi Study On The Use Of Simulation In Undergraduate Nursing Education, Diana L. Bailey

Dissertations

The lack of traditional clinical sites for nursing students has prompted a surge in simulation as an innovative teaching strategy in undergraduate nursing education. The International Nursing Association for Clinical Simulation and Learning (INASCL) developed the INACSL Standards of Best Practice: SimulationSM to direct schools of nursing in implementing high-quality simulations. As simulated experiences replace traditional clinical experiences, it is imperative that simulated experiences replicate real-life patient scenarios. The purpose of this Delphi study was to establish consensus on the use of the INACSL Standards of Best Practice: Simulation in undergraduate nursing education. The conceptual frameworks guiding this study were …

Using Variable-Resolution Grids To Model Precipitation From Atmospheric Rivers Around The Greenland Ice Sheet, Annelise Waling, Adam Herrington, Katharine Duderstadt, Jack E. Dibb, Elizabeth A. Burakowski

Faculty Publications

Atmospheric rivers (ARs) are synoptic-scale features that transport moisture poleward and may cause short-duration, high-volume melt events on the Greenland ice sheet (GrIS). In contrast with traditional climate modeling studies that rely on coarse (1 to 2°) grids, this project investigates the effectiveness of variable-resolution (VR) grids in modeling ARs and their subsequent precipitation using refined grid spacing (0.25 and 0.125°) around the GrIS and 1° grid spacing for the rest of the globe in a coupled land–atmosphere model simulation. VR simulations from the Community Earth System Model version 2.2 (CESM2.2) bridge the gap between the limitations of global and …

The Relationship Between The Neighborhood Environment, Health Behaviors And Health Outcomes Among Urban Hispanics In New York City, Manuel C. Co Jr.

Dissertations

Hispanics account for more than half of the total United States (US) population growth between 2000 and 2010. To gain a comprehensive understanding of a predominantly Hispanic urban community in Northern Manhattan, the aims of this cross-sectional observational study were: (1) to characterize the actual and perceived neighborhood food environment in Northern Manhattan, (2) to understand the relationship between the actual and perceived neighborhood food environment, sociodemographic characteristics and the likelihood of consuming five or more servings of fruits and vegetables per day, and (3) to describe the contribution of participants' sociodemographic characteristics and health behavior to their health outcomes.

Attitudes, Subjective Norms, And Perceived Behavioral Control Of Perianesthesia Nurses' Intentions To Engage In Mindful Self-Care, Brenda K. Sanya

Dissertations

The purpose of this study was to examine the relationships among attitudes, subjective norms, perceived behavioral control, and intentions to engage in mindful self-care among nurses working in the peri-anesthesia setting. The study utilized cross-sectional design and was guided by the Theory of Planned Behavior.

How State Universities Are Addressing The Shortage Of Cybersecurity Professionals In The United States, Gary Harris

Journal of Cybersecurity Education, Research and Practice

Cybersecurity threats have been a serious and growing problem for decades. In addition, a severe shortage of cybersecurity professionals has been proliferating for nearly as long. These problems exist in the United States and globally and are well documented in literature. This study examined what state universities are doing to help address the shortage of cybersecurity professionals since higher education institutions are a primary source to the workforce pipeline. It is suggested that the number of cybersecurity professionals entering the workforce is related to the number of available programs. Thus increasing the number of programs will increase the number of …

Student Life E-Newsletter September 23, 2024, Seattle University School Of Law Student Life

Student Life E-Newsletters

No abstract provided.

The Rider (2024-09-23), Natalie Lapsley

The Rider Archives

Vol.10 No.5

Titan Traditions Continue At Iwu’S Homecoming And Family Weekend, Julia Perez

News and Events (Discontinued Series)

No abstract provided.

Examining Daily-Self Weighing As A Stand-Alone Intervention For Obesity Management, Ashley Parish

All ETDs from UAB

Obesity is an epidemic that has substantial implications for both individuals with the disease as well as the healthcare system in the United States. Individuals with obesity are at increased risk for developing associated co-morbid conditions such as cardiovascular disease, type 2 diabetes, and some forms of cancer, which can affect quality of life and lead to mortality. There are many health behavior interventions which target weight loss, maintenance of weight loss, or weight gain prevention in those with obesity; however, interventions have unique barriers that can vary based on personal, environmental, and social factors. Primary care (PC) settings, which …

The C-Terminal 4cxxc-Type Zinc Finger Domain Of Cdca7 Recognizes Hemimethylated Dna And Modulates Activities Of Chromatin Remodeling Enzyme Hells, Akeo Shinkai, Hideharu Hashimoto, Chikako Shimura, Hiroaki Fujimoto, Kei Fukuda, Naoki Horikoshi, Masaki Okano, Hitoshi Niwa, Erik W Debler, Hitoshi Kurumizaka, Yoichi Shinkai

Department of Biochemistry and Molecular Biology Faculty Papers

The chromatin-remodeling enzyme helicase lymphoid-specific (HELLS) interacts with cell division cycle-associated 7 (CDCA7) on nucleosomes and is involved in the regulation of DNA methylation in higher organisms. Mutations in these genes cause immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome, which also results in DNA hypomethylation of satellite repeat regions. We investigated the functional domains of human CDCA7 in HELLS using several mutant CDCA7 proteins. The central region is critical for binding to HELLS, activation of ATPase, and nucleosome sliding activities of HELLS-CDCA7. The N-terminal region tends to inhibit ATPase activity. The C-terminal 4CXXC-type zinc finger domain contributes to CpG …

Trends In Reimbursement For All Billable Total Joint Replacement Procedures: An Analysis Of The Medicare Part B Database From 2013-2021, Nithin Gupta, Morgan Turnow, Jagroop Doad, Forrest Dunivin, Emily Sydow, Tyler Williamson, Taylor Manes, Jia Bao Lin, Jignesh Patel

Student Publications

Introduction

Total joint arthroplasty (TJA) remains highly prevalent, nearly rivaling the prevalence of other challenging conditions such as heart failure. Annually, there are over 790,000 total knee replacements and more than 450,000 hip replacements performed in the United States. As the demand for TJAs steadily increases, issues related to access, and quality have become increasingly pronounced. Despite the significant annual rise in volume of surgeries, there exists a notable gap pertaining to the epidemiology and reimbursement rates of TJAs within the United States.

Methods

Publicly available data from the Centers for Medicare & Medicaid Services Database was extracted. The dataset …

Metadegron: Multimodal Feature-Integrated Protein Language Model For Predicting E3 Ligase Targeted Degrons, Mengqiu Zheng, Shaofeng Lin, Kunqi Chen, Ruifeng Hu, Liming Wang, Zhongming Zhao, Haodong Xu

Faculty, Staff and Student Publications

Protein degradation through the ubiquitin proteasome system at the spatial and temporal regulation is essential for many cellular processes. E3 ligases and degradation signals (degrons), the sequences they recognize in the target proteins, are key parts of the ubiquitin-mediated proteolysis, and their interactions determine the degradation specificity and maintain cellular homeostasis. To date, only a limited number of targeted degron instances have been identified, and their properties are not yet fully characterized. To tackle on this challenge, here we develop a novel deep-learning framework, namely MetaDegron, for predicting E3 ligase targeted degron by integrating the protein language model and comprehensive …

Mta-Cooperative Prmt5 Inhibitors Enhance T Cell-Mediated Antitumor Activity In Mtap-Loss Tumors, Si Chen, Jiakai Hou, Roshni Jaffery, Ashley Guerrero, Rongjie Fu, Leilei Shi, Ningbo Zheng, Ritu Bohat, Nicholas A Egan, Chengtai Yu, Sana Sharif, Yue Lu, Wei He, Shuyue Wang, Donjeta Gjuka, Everett M Stone, Pooja Anil Shah, Jordi Rodon Ahnert, Taiping Chen, Xinli Liu, Mark T Bedford, Han Xu, Weiyi Peng

Faculty, Staff and Student Publications

BACKGROUND: Hyperactivated protein arginine methyltransferases (PRMTs) are implicated in human cancers. Inhibiting tumor intrinsic PRMT5 was reported to potentiate antitumor immune responses, highlighting the possibility of combining PRMT5 inhibitors (PRMT5i) with cancer immunotherapy. However, global suppression of PRMT5 activity impairs the effector functions of immune cells. Here, we sought to identify strategies to specifically inhibit PRMT5 activity in tumor tissues and develop effective PRMT5i-based immuno-oncology (IO) combinations for cancer treatment, particularly for methylthioadenosine phosphorylase (MTAP)-loss cancer.

METHODS: Isogeneic tumor lines with and without MTAP loss were generated by CRISPR/Cas9 knockout. The effects of two PRMT5 inhibitors (GSK3326595 and MRTX1719) were …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Incorporating Genai Into Information Literacy Instruction: Find Engineering Standards, Lauren Todd

Generative AI Teaching Activities

Students will prompt GenAI tools to find relevant engineering standards that might apply to their mechanical engineering design project, then they must evaluate the responses.

Thrombectomy For Stroke With Large Infarct On Noncontrast Ct: The Tesla Randomized Clinical Trial, Writing Committee For The Tesla Investigators, Albert J Yoo, Osama O Zaidat, Sunil A Sheth, Ansaar T Rai, Santiago Ortega-Gutierrez, Curtis A Given, Syed F Zaidi, Ramesh Grandhi, Hugo Cuellar, Maxim Mokin, Jeffrey M Katz, Amer Alshekhlee, Muhammad A Taqi, Sameer A Ansari, Adnan H Siddiqui, Nobl Barazangi, Joey D English, Alberto Maud, Jawad Kirmani, Rishi Gupta, Dileep R Yavagal, Jason Tarpley, Dhruvil J Pandya, Marshall C Cress, Sushrut Dharmadhikari, Kaiz S Asif, Tareq Kass-Hout, Ajit S Puri, Nazli Janjua, Aniel Q Majjhoo, Aamir Badruddin, Randall C Edgell, Rakesh Khatri, Larry Morgan, Anmar Razak, Alicia Zha, Priyank Khandelwal, Nils Mueller-Kronast, Dennis J Rivet, Thomas Wolfe, Brian Snelling, Ali Sultan-Qurraie, Shao-Pow Lin, Rajkamal Khangura, Alejandro M Spiotta, Parita Bhuva, Sergio Salazar-Marioni, Eugene Lin, Abdul R Tarabishy, Edgar A Samaniego, Murali K Kolikonda, Mouhammad A Jumaa, Vivek K Reddy, Pankaj Sharma, Olvert A Berkhemer, Pieter-Jan Van Doormaal, Adriaan C G M Van Es, Wim H Van Zwam, Bart J Emmer, Ludo F Beenen, Charles B L M Majoie, Nancy Buderer, Michelle A Detry, Anna Bosse, Todd L Graves, Christina Saunders, Lucas Elijovich, Ashutosh Jadhav, Mary Patterson, Hannah Slight, Kristine Below, Sami Al Kasab, Tesla Investigators

Faculty, Staff and Student Publications

Importance: Recent large infarct thrombectomy trials used heterogeneous imaging modalities and time windows for patient selection. Noncontrast computed tomographic (CT) scan is the most common stroke imaging approach. It remains uncertain whether thrombectomy is effective for patients with large infarcts identified using noncontrast CT alone within 24 hours of stroke onset.

Objective: To evaluate the effect of thrombectomy in patients with a large infarct on a noncontrast CT scan within 24 hours of onset.

Design, setting, and participants: Open-label, blinded-end point, bayesian-adaptive randomized trial with interim analyses for early stopping (futility or success) or population enrichment, which was conducted at …

Dek::Aff2 Fusion-Associated Squamous Cell Carcinoma: A Case Series With Literature Review On An Emerging And Challenging Entity, Sara E Amin, James S Lewis, Julia A Bridge, Jen-Fan Hang, Udit Naik, Justin A Bishop, Karan Saluja

Faculty, Staff and Student Publications

Purpose: DEK::AFF2 fusion-associated squamous cell carcinoma (DEK::AFF2 SCC), also reported in the literature as low-grade papillary sinonasal (Schneiderian) carcinoma (LGPSC), is a rare, primarily bland-appearing, but locally aggressive neoplasm. Morphologically, these tumors can closely resemble sinonasal papilloma (SP), especially on small or limited biopsy, often leading to misdiagnosis. DEK::AFF2 SCC is devoid of the underlying mutually exclusive EGFR or KRAS driver mutations of SP, suggesting it may represent a distinct unique entity.

Methods: In this study, we conducted a retrospective search of "unusual" SP reported either as atypical, dysplastic, or suspicious for malignant transformation at our institution in the last …

Austronesian Maritime Migrations: Past And Present - A.B. Lapian Memorial Lecture 2024, James J. Fox

Antropologi Indonesia

This lecture is given in honour of A.B. Lapian whom I had the good fortunate to know. He was a notable scholar whose knowledge of the maritime world of Nusantara was exemplary. As an historian, he had a clear understanding of the broad contours of regional maritime history but equally, he had a concern for the illuminating details of that history. He had a special interest in the Bajau as a maritime population and in their crucial historical role in the trepang trade. I was fortunate to have participated in the International Seminar Professor Lapian organized on the Bajau in …

Jessie Jia '25 Studies Class Conflicts, Identity Of Migrants In America, Jeffery Woodard

News and Events (Discontinued Series)

No abstract provided.

Diet Culture On Tiktok: A Descriptive Content Analysis, Emily Munro, Gabriella Wells, Rigel Paciente, Nicole Wickens, Daniel Ta, Joelie Mandzufas, Karen Lombardi, Alix Woolard

Research outputs 2022 to 2026

Objective: To investigate how dieting is portrayed on TikTok and the potential implications for public health considering the effect of diet culture on eating disorders amongst young people. Design: A cross-sectional descriptive content analysis of 250 videos from the five most popular diet-related hashtags. A codebook was developed to analyse the content of the videos and collect the engagement for each video (likes, comments and shares). Setting: TikTok website. Participants: There were no participants in this study. Results: More than half of the videos portrayed 'body checking', a potentially harmful practice for body image. Of the videos that represented body …