Digital Commons Network^™

The Relationship Between The Neighborhood Environment, Health Behaviors And Health Outcomes Among Urban Hispanics In New York City, Manuel C. Co Jr.

Dissertations

Hispanics account for more than half of the total United States (US) population growth between 2000 and 2010. To gain a comprehensive understanding of a predominantly Hispanic urban community in Northern Manhattan, the aims of this cross-sectional observational study were: (1) to characterize the actual and perceived neighborhood food environment in Northern Manhattan, (2) to understand the relationship between the actual and perceived neighborhood food environment, sociodemographic characteristics and the likelihood of consuming five or more servings of fruits and vegetables per day, and (3) to describe the contribution of participants' sociodemographic characteristics and health behavior to their health outcomes.

Attitudes, Subjective Norms, And Perceived Behavioral Control Of Perianesthesia Nurses' Intentions To Engage In Mindful Self-Care, Brenda K. Sanya

Dissertations

The purpose of this study was to examine the relationships among attitudes, subjective norms, perceived behavioral control, and intentions to engage in mindful self-care among nurses working in the peri-anesthesia setting. The study utilized cross-sectional design and was guided by the Theory of Planned Behavior.

How State Universities Are Addressing The Shortage Of Cybersecurity Professionals In The United States, Gary Harris

Journal of Cybersecurity Education, Research and Practice

Cybersecurity threats have been a serious and growing problem for decades. In addition, a severe shortage of cybersecurity professionals has been proliferating for nearly as long. These problems exist in the United States and globally and are well documented in literature. This study examined what state universities are doing to help address the shortage of cybersecurity professionals since higher education institutions are a primary source to the workforce pipeline. It is suggested that the number of cybersecurity professionals entering the workforce is related to the number of available programs. Thus increasing the number of programs will increase the number of …

Student Life E-Newsletter September 23, 2024, Seattle University School Of Law Student Life

Student Life E-Newsletters

No abstract provided.

The Rider (2024-09-23), Natalie Lapsley

The Rider Archives

Vol.10 No.5

Titan Traditions Continue At Iwu’S Homecoming And Family Weekend, Julia Perez

News and Events (Discontinued Series)

No abstract provided.

Examining Daily-Self Weighing As A Stand-Alone Intervention For Obesity Management, Ashley Parish

All ETDs from UAB

Obesity is an epidemic that has substantial implications for both individuals with the disease as well as the healthcare system in the United States. Individuals with obesity are at increased risk for developing associated co-morbid conditions such as cardiovascular disease, type 2 diabetes, and some forms of cancer, which can affect quality of life and lead to mortality. There are many health behavior interventions which target weight loss, maintenance of weight loss, or weight gain prevention in those with obesity; however, interventions have unique barriers that can vary based on personal, environmental, and social factors. Primary care (PC) settings, which …

The C-Terminal 4cxxc-Type Zinc Finger Domain Of Cdca7 Recognizes Hemimethylated Dna And Modulates Activities Of Chromatin Remodeling Enzyme Hells, Akeo Shinkai, Hideharu Hashimoto, Chikako Shimura, Hiroaki Fujimoto, Kei Fukuda, Naoki Horikoshi, Masaki Okano, Hitoshi Niwa, Erik W Debler, Hitoshi Kurumizaka, Yoichi Shinkai

Department of Biochemistry and Molecular Biology Faculty Papers

The chromatin-remodeling enzyme helicase lymphoid-specific (HELLS) interacts with cell division cycle-associated 7 (CDCA7) on nucleosomes and is involved in the regulation of DNA methylation in higher organisms. Mutations in these genes cause immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome, which also results in DNA hypomethylation of satellite repeat regions. We investigated the functional domains of human CDCA7 in HELLS using several mutant CDCA7 proteins. The central region is critical for binding to HELLS, activation of ATPase, and nucleosome sliding activities of HELLS-CDCA7. The N-terminal region tends to inhibit ATPase activity. The C-terminal 4CXXC-type zinc finger domain contributes to CpG …

Trends In Reimbursement For All Billable Total Joint Replacement Procedures: An Analysis Of The Medicare Part B Database From 2013-2021, Nithin Gupta, Morgan Turnow, Jagroop Doad, Forrest Dunivin, Emily Sydow, Tyler Williamson, Taylor Manes, Jia Bao Lin, Jignesh Patel

Student Publications

Introduction

Total joint arthroplasty (TJA) remains highly prevalent, nearly rivaling the prevalence of other challenging conditions such as heart failure. Annually, there are over 790,000 total knee replacements and more than 450,000 hip replacements performed in the United States. As the demand for TJAs steadily increases, issues related to access, and quality have become increasingly pronounced. Despite the significant annual rise in volume of surgeries, there exists a notable gap pertaining to the epidemiology and reimbursement rates of TJAs within the United States.

Methods

Publicly available data from the Centers for Medicare & Medicaid Services Database was extracted. The dataset …

Metadegron: Multimodal Feature-Integrated Protein Language Model For Predicting E3 Ligase Targeted Degrons, Mengqiu Zheng, Shaofeng Lin, Kunqi Chen, Ruifeng Hu, Liming Wang, Zhongming Zhao, Haodong Xu

Faculty, Staff and Student Publications

Protein degradation through the ubiquitin proteasome system at the spatial and temporal regulation is essential for many cellular processes. E3 ligases and degradation signals (degrons), the sequences they recognize in the target proteins, are key parts of the ubiquitin-mediated proteolysis, and their interactions determine the degradation specificity and maintain cellular homeostasis. To date, only a limited number of targeted degron instances have been identified, and their properties are not yet fully characterized. To tackle on this challenge, here we develop a novel deep-learning framework, namely MetaDegron, for predicting E3 ligase targeted degron by integrating the protein language model and comprehensive …

Mta-Cooperative Prmt5 Inhibitors Enhance T Cell-Mediated Antitumor Activity In Mtap-Loss Tumors, Si Chen, Jiakai Hou, Roshni Jaffery, Ashley Guerrero, Rongjie Fu, Leilei Shi, Ningbo Zheng, Ritu Bohat, Nicholas A Egan, Chengtai Yu, Sana Sharif, Yue Lu, Wei He, Shuyue Wang, Donjeta Gjuka, Everett M Stone, Pooja Anil Shah, Jordi Rodon Ahnert, Taiping Chen, Xinli Liu, Mark T Bedford, Han Xu, Weiyi Peng

Faculty, Staff and Student Publications

BACKGROUND: Hyperactivated protein arginine methyltransferases (PRMTs) are implicated in human cancers. Inhibiting tumor intrinsic PRMT5 was reported to potentiate antitumor immune responses, highlighting the possibility of combining PRMT5 inhibitors (PRMT5i) with cancer immunotherapy. However, global suppression of PRMT5 activity impairs the effector functions of immune cells. Here, we sought to identify strategies to specifically inhibit PRMT5 activity in tumor tissues and develop effective PRMT5i-based immuno-oncology (IO) combinations for cancer treatment, particularly for methylthioadenosine phosphorylase (MTAP)-loss cancer.

METHODS: Isogeneic tumor lines with and without MTAP loss were generated by CRISPR/Cas9 knockout. The effects of two PRMT5 inhibitors (GSK3326595 and MRTX1719) were …

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Incorporating Genai Into Information Literacy Instruction: Find Engineering Standards, Lauren Todd

Generative AI Teaching Activities

Students will prompt GenAI tools to find relevant engineering standards that might apply to their mechanical engineering design project, then they must evaluate the responses.

Thrombectomy For Stroke With Large Infarct On Noncontrast Ct: The Tesla Randomized Clinical Trial, Writing Committee For The Tesla Investigators, Albert J Yoo, Osama O Zaidat, Sunil A Sheth, Ansaar T Rai, Santiago Ortega-Gutierrez, Curtis A Given, Syed F Zaidi, Ramesh Grandhi, Hugo Cuellar, Maxim Mokin, Jeffrey M Katz, Amer Alshekhlee, Muhammad A Taqi, Sameer A Ansari, Adnan H Siddiqui, Nobl Barazangi, Joey D English, Alberto Maud, Jawad Kirmani, Rishi Gupta, Dileep R Yavagal, Jason Tarpley, Dhruvil J Pandya, Marshall C Cress, Sushrut Dharmadhikari, Kaiz S Asif, Tareq Kass-Hout, Ajit S Puri, Nazli Janjua, Aniel Q Majjhoo, Aamir Badruddin, Randall C Edgell, Rakesh Khatri, Larry Morgan, Anmar Razak, Alicia Zha, Priyank Khandelwal, Nils Mueller-Kronast, Dennis J Rivet, Thomas Wolfe, Brian Snelling, Ali Sultan-Qurraie, Shao-Pow Lin, Rajkamal Khangura, Alejandro M Spiotta, Parita Bhuva, Sergio Salazar-Marioni, Eugene Lin, Abdul R Tarabishy, Edgar A Samaniego, Murali K Kolikonda, Mouhammad A Jumaa, Vivek K Reddy, Pankaj Sharma, Olvert A Berkhemer, Pieter-Jan Van Doormaal, Adriaan C G M Van Es, Wim H Van Zwam, Bart J Emmer, Ludo F Beenen, Charles B L M Majoie, Nancy Buderer, Michelle A Detry, Anna Bosse, Todd L Graves, Christina Saunders, Lucas Elijovich, Ashutosh Jadhav, Mary Patterson, Hannah Slight, Kristine Below, Sami Al Kasab, Tesla Investigators

Faculty, Staff and Student Publications

Importance: Recent large infarct thrombectomy trials used heterogeneous imaging modalities and time windows for patient selection. Noncontrast computed tomographic (CT) scan is the most common stroke imaging approach. It remains uncertain whether thrombectomy is effective for patients with large infarcts identified using noncontrast CT alone within 24 hours of stroke onset.

Objective: To evaluate the effect of thrombectomy in patients with a large infarct on a noncontrast CT scan within 24 hours of onset.

Design, setting, and participants: Open-label, blinded-end point, bayesian-adaptive randomized trial with interim analyses for early stopping (futility or success) or population enrichment, which was conducted at …

Dek::Aff2 Fusion-Associated Squamous Cell Carcinoma: A Case Series With Literature Review On An Emerging And Challenging Entity, Sara E Amin, James S Lewis, Julia A Bridge, Jen-Fan Hang, Udit Naik, Justin A Bishop, Karan Saluja

Faculty, Staff and Student Publications

Purpose: DEK::AFF2 fusion-associated squamous cell carcinoma (DEK::AFF2 SCC), also reported in the literature as low-grade papillary sinonasal (Schneiderian) carcinoma (LGPSC), is a rare, primarily bland-appearing, but locally aggressive neoplasm. Morphologically, these tumors can closely resemble sinonasal papilloma (SP), especially on small or limited biopsy, often leading to misdiagnosis. DEK::AFF2 SCC is devoid of the underlying mutually exclusive EGFR or KRAS driver mutations of SP, suggesting it may represent a distinct unique entity.

Methods: In this study, we conducted a retrospective search of "unusual" SP reported either as atypical, dysplastic, or suspicious for malignant transformation at our institution in the last …

Austronesian Maritime Migrations: Past And Present - A.B. Lapian Memorial Lecture 2024, James J. Fox

Antropologi Indonesia

This lecture is given in honour of A.B. Lapian whom I had the good fortunate to know. He was a notable scholar whose knowledge of the maritime world of Nusantara was exemplary. As an historian, he had a clear understanding of the broad contours of regional maritime history but equally, he had a concern for the illuminating details of that history. He had a special interest in the Bajau as a maritime population and in their crucial historical role in the trepang trade. I was fortunate to have participated in the International Seminar Professor Lapian organized on the Bajau in …

Jessie Jia '25 Studies Class Conflicts, Identity Of Migrants In America, Jeffery Woodard

News and Events (Discontinued Series)

No abstract provided.

Diet Culture On Tiktok: A Descriptive Content Analysis, Emily Munro, Gabriella Wells, Rigel Paciente, Nicole Wickens, Daniel Ta, Joelie Mandzufas, Karen Lombardi, Alix Woolard

Research outputs 2022 to 2026

Objective: To investigate how dieting is portrayed on TikTok and the potential implications for public health considering the effect of diet culture on eating disorders amongst young people. Design: A cross-sectional descriptive content analysis of 250 videos from the five most popular diet-related hashtags. A codebook was developed to analyse the content of the videos and collect the engagement for each video (likes, comments and shares). Setting: TikTok website. Participants: There were no participants in this study. Results: More than half of the videos portrayed 'body checking', a potentially harmful practice for body image. Of the videos that represented body …

Re: Comment Letter For Draft Bpsou 2023 Groundwater Data Summary Report (Dated May 31, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

The Elephant In The Dark Room: A Response To Fair Notice, The Rule Of Law And Reforming Qualified Immunity, Teressa E. Ravenell

Faculty Publications

In response to Professor Chapman’s Fair Notice, the Rule of Law, and Reforming Qualified Immunity, this article examines the viability of Chapman’s proposal to reform qualified immunity by focusing on the “fair notice” rationale. Chapman argues that government officials should not be shielded from liability in cases where they acted in bad faith, violated criminal laws, or engaged in conduct malum in se. This article explores whether such a proposal could meaningfully alter qualified immunity litigation and concludes that significant procedural and historical barriers make this reform unlikely to succeed.

Toward Standardized Brain Tumor Tissue Processing Protocols In Neuro-Oncology: A Perspective For Gliomas And Beyond, Manmeet Ahluwalia, Michael Mcdermott

All Publications

Implementation of standardized protocols in neurooncology during the surgical resection of brain tumors is needed to advance the clinical treatment paradigms that use tissue for diagnosis, prognosis, bio-banking, and treatment. Currently recommendations on intraoperative tissue procurement only exist for diffuse gliomas but management of other brain tumor subtypes can also benefit from these protocols. Fresh tissue from surgical resection can now be used for intraoperative diagnostics and functional precision medicine assays. A multidisciplinary neuro-oncology perspective is critical to develop the best avenues for practical standardization. This perspective from the multidisciplinary Oncology Tissue Advisory Board (OTAB) discusses current advances, future directions, …

Food Security - What It Is And Why It Matters, Makell Corry, Palak Gupta

All Current Publications

Insufficient access to safe and nutritious foods can severely impact physical, mental, and social well-being. Without proper nutrition, focus levels, energy, and immune system support can decline, leading to long-term health challenges. This fact sheet addresses the pillars of food security and reviews government programs that help address insufficient food. It also offers recommendations of ways to volunteer to address the problem in your community.

Reducing Food Waste At Home, Makell Corry, Palak Gupta, Jose Brandao

All Current Publications

As food is discarded, resources such as money and water are wasted by producing food that will not be eaten and then transporting it to landfills. There are many solutions for reducing food loss. This fact sheet reviews ways you can build successful habits to address food waste.

Recent Climate Change In Utah, 1870-2023, Scott Hotaling, Kendall Becker

All Current Publications

Climate change is impacting Utah. Forty-five years of temperature data show that Utah is steadily warming, which, in turn, is driving declines in winter snowpack, shifting the timing and amount of available water, increasing fire risk, and causing ecological change. This fact sheet addresses changes in Utah's temperature, precipitation and snowpack, streamflow, wildfire, and ecology.

Pibly Residential Programs, Inc. V. Rodriguez

All Decisions

The court dismissed the landlord's holdover petition because the notice of termination was defective. The notice failed to identify the former subtenant, who was the mother of the named respondent and the alleged licensor, rendering the notice vague and imprecise. The court found that this failure to identify "essential actors" and provide a clear, consistent basis for the proceeding made the notice unreasonable in light of the circumstances and prevented the tenant from preparing a proper defense. The proceeding was dismissed without prejudice, allowing the landlord to recommence the case with a new, proper predicate notice.

Cs Melrose Site D, Llc V. Rodriguez

All Decisions

Handwritten Opinion. The landlord initiated a holdover proceeding against the tenant, claiming the tenant failed to provide access for repairs. The tenant moved to dismiss, arguing the notice to cure was vague and insufficient to put the tenant on notice of the specific violations. The court agreed, finding that the notice lacked specific details about the dates, times, and factual circumstances of the alleged access denials. As a result, the court dismissed the case.

Semiautomated Generation Of Species-Specific Training Data From Large, Unlabeled Acoustic Datasets For Deep Supervised Birdsong Isolation, Justin Sasek, Brendan Allison, Andrea Contina, David Knobles, Preston Wilson, Timothy Keitt

School of Integrative Biological & Chemical Sciences Faculty Publications

Background

Bioacoustic monitoring is an effective and minimally invasive method to study wildlife ecology. However, even the state-of-the-art techniques for analyzing birdsongs decrease in accuracy in the presence of extraneous signals such as anthropogenic noise and vocalizations of non-target species. Deep supervised source separation (DSSS) algorithms have been shown to effectively separate mixtures of animal vocalizations. However, in practice, recording sites also have site-specific variations and unique background audio that need to be removed, warranting the need for site-specific data.

Methods

Here, we test the potential of training DSSS models on site-specific bird vocalizations and background audio. We used a …

Historical Redlining, Contemporary Gentrification, And Severe Maternal Morbidity In California, 2005-2018, Xing Gao, Rachel Morello-Frosch, Amani M. Nuru-Jeter, Jonathan M. Snowden, Suzan L. Carmichael, Mahasin S. Mujahid

OHSU-PSU School of Public Health Faculty Publications and Presentations

Importance Historically redlined neighborhoods may experience disinvestment, influencing their likelihood of gentrification, a process of neighborhood (re-)development that unequally distributes harms and benefits by race and class. Understanding the combined outcomes of redlining and gentrification informs how the mutually constitutive systems of structural racism and racial capitalism affect pregnancy outcomes. Objective To examine if historical redlining and contemporary gentrification is associated with increased severe maternal morbidity (SMM) odds. Design, Setting, and Participants This cross-sectional study used data from a statewide population-based sample of all live hospital births at 20 weeks’ gestation or more between 2005 and 2018 in California. Analysis …

Strategic Stabilization Of Arousal Boosts Sustained Attention, Jan Willem De Gee, Zakir Mridha, Marisa Hudson, Yanchen Shi, Hannah Ramsaywak, Spencer Smith, Nishad Karediya, Matthew Thompson, Kit Jaspe, Hong Jiang, Wenhao Zhang, Matthew J Mcginley

Duncan NRI Faculty and Staff Publications

Arousal and motivation interact to profoundly influence behavior. For example, experience tells us that we have some capacity to control our arousal when appropriately motivated, such as staying awake while driving a motor vehicle. However, little is known about how arousal and motivation jointly influence decision computations, including if and how animals, such as rodents, adapt their arousal state to their needs. Here, we developed and show results from an auditory, feature-based, sustained-attention task with intermittently shifting task utility. We use pupil size to estimate arousal across a wide range of states and apply tailored signal detection theoretic, hazard function …

Analyzing Crime Patterns Through Artificial Intelligence, Rashid Khalid Mohamed Abdalla Alhammadi

Theses

This paper examines how crime patterns affect predictive policing in Denver, Colorado. Modern crimes like cybercrime and identity theft have challenged traditional crime research methods, necessitating data-driven ones. In this context, the study examines how machine learning and AI can identify and forecast crime trends across neighborhoods, timeframes, and other aspects. The research sought to understand crime's dynamics and socioeconomic effects. The study collected data using a mixed-method approach based on questions about crime kinds, rates, and sociodemographic characteristics. A large chunk of the data came from public databases and targeted neighborhood surveys. Regression analysis, decision trees, and neural network …