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Molecular And Clinical Features Of Pancreatic Acinar Cell Carcinoma: A Single-Institution Case Series, Ashwathy Balachandran Pillai, Mahmoud Yousef, Abdelrahman Yousef, Kristin D Alfaro-Munoz, Brandon G Smaglo, Jason Willis, Robert A Wolff, Shubham Pant, Mark W Hurd, Anirban Maitra, Huamin Wang, Matthew Harold G Katz, Laura R Prakash, Ching-Wei D Tzeng, Rebecca Snyder, Luca F Castelnovo, Anthony Chen, Andrey Kravets, Kseniia Kudriavtseva, Artem Tarasov, Kirill Kryukov, Haoqiang Ying, John Paul Shen, Dan Zhao Oct 2024

Molecular And Clinical Features Of Pancreatic Acinar Cell Carcinoma: A Single-Institution Case Series, Ashwathy Balachandran Pillai, Mahmoud Yousef, Abdelrahman Yousef, Kristin D Alfaro-Munoz, Brandon G Smaglo, Jason Willis, Robert A Wolff, Shubham Pant, Mark W Hurd, Anirban Maitra, Huamin Wang, Matthew Harold G Katz, Laura R Prakash, Ching-Wei D Tzeng, Rebecca Snyder, Luca F Castelnovo, Anthony Chen, Andrey Kravets, Kseniia Kudriavtseva, Artem Tarasov, Kirill Kryukov, Haoqiang Ying, John Paul Shen, Dan Zhao

Faculty, Staff and Student Publications

Objectives: Acinar cell carcinoma (ACC) accounts for about 1% of pancreatic cancers. The molecular and clinical features of ACC are less characterized than those of pancreatic ductal adenocarcinoma. Methods: We retrospectively evaluated the clinical and molecular features of ACC patients who underwent germline and/or somatic molecular testing at The University of Texas MD Anderson Cancer Center from 2008 to 2022 and two cases from 2023-2024 who underwent RNA and TME analysis by Boston Gene. Patient information was extracted from our institutional database with the approval of the Institutional Review Board. Results: We identified 16 patients with available molecular testing …


Federal Election Commission And Indiana Secretary Of State Campaign Finance Information Resoures, Bert Chapman Oct 2024

Federal Election Commission And Indiana Secretary Of State Campaign Finance Information Resoures, Bert Chapman

Libraries Faculty and Staff Presentations

This presentation covers campaign finance information resources produced by the Federal Election Commission (FEC) and Indiana Secretary of State. It describes how these agencies began, details how they oversee and regulate U.S. federal and Indiana state elections, and documents contributions made by individuals, organizations, political parties, and political action committees to individual candidates and organizations. Reporting documentation on these election races is also included.


The Antecedents Of The Experience Of Light In Dreams, Gregory Scott Sparrow, Ryan Hurd Oct 2024

The Antecedents Of The Experience Of Light In Dreams, Gregory Scott Sparrow, Ryan Hurd

Counseling Faculty Publications

The experience of inner light and ecstasy is widely accepted as a universal mystical experience, regardless of cultural or religious context. While one can read first-hand accounts in the historical record, the direct experience of light remains elusive for most people. This study analyzes a series of dream-based experiences of light provided by a single subject. In our analysis of 19 dreams, we pursue a process-oriented, relational analysis based on co-creative dream theory, which views the dream as an interactive experience in real time rather than a fixed product of the unconscious mind. By analyzing dreams as relational events, in …


Wealth, Marriage, And Sex Selection, Girija Borker, Jan Eeckhout, Nancy Luke, Shantidani Minz, Kaivan Munshi, Soumya Swaminathan Oct 2024

Wealth, Marriage, And Sex Selection, Girija Borker, Jan Eeckhout, Nancy Luke, Shantidani Minz, Kaivan Munshi, Soumya Swaminathan

Cowles Foundation Discussion Papers

Two mechanisms have been proposed to explain sex selection in India: son preference in which parents desire a male heir and daughter aversion in which dowry payments make parents worse off with girls. Our model incorporates both mechanisms, providing micro-foundations, based on the organization of the marriage institution, for daughter aversion. Marital matching, sex selection, and dowries are jointly determined in the model, whose implications are tested on a representative sample of rural households. Simulations of the model indicate that existing policies targeting daughter aversion might exacerbate the problem, while identifying other policies that could be effective.


China Maritime Report No. 42: Invasion Plans: Operation Causeway And Taiwan's Defense In World War Ii, Ian Easton Oct 2024

China Maritime Report No. 42: Invasion Plans: Operation Causeway And Taiwan's Defense In World War Ii, Ian Easton

CMSI China Maritime Reports

Main Findings

  • During World War II, the United States and the Empire of Japan each developed plans and marshaled forces for a climactic battle over Taiwan. Both sides regarded the island as an area of strategic consequence.
  • Code-named Operation CAUSEWAY, the American invasion of Taiwan would have been the largest amphibious campaign in the Pacific Theater and the largest sea-air-land engagement in world history.
  • Strategists in Japan believed the attack was coming and designed a blueprint for the defense of Taiwan and the Ryukyu Islands called SHO-GO(捷 2 号作戦, or “Operation Victory No. 2”), which envisioned a bloody campaign of …


Characterizing The Influence Of Metabolism On Steady State Water Exchange In Yeast As A Potential Mri Diagnostic Biomarker, Samantha Mumford Oct 2024

Characterizing The Influence Of Metabolism On Steady State Water Exchange In Yeast As A Potential Mri Diagnostic Biomarker, Samantha Mumford

Dissertations and Theses

Under conditions of ionic equilibrium with the environment a cell maintains a constant volume yet rapidly exchanges water molecules with the extracellular space. The rate constant for steady state water efflux, kio, can be measured using contrast enhanced magnetic resonance (CE-MR). The active water cycling (AWC) hypothesis is puts forward that kio is primarily influenced by cellular ATP levels and H+ ATPase activity at the cell membrane. Due to the correlation between kio and ATP levels, kio is thought to be a probable MRI biomarker for metabolic diseases such as cancer. Yet, the molecular …


Prevalence And Prognostication Of Cd5+ Mature T-Cell Lymphomas, Omar Elghawy, Miao Cao, Jason Xu, Daniel J. Landsburg, Jakub Svoboda, Sunita D. Nasta, Elise A. Chong, Stephen J. Schuster, Colin J. Thomas, Jordan S. Carter, Montreh Tavakkoli, Marco Ruella, Stefan K. Barta Oct 2024

Prevalence And Prognostication Of Cd5+ Mature T-Cell Lymphomas, Omar Elghawy, Miao Cao, Jason Xu, Daniel J. Landsburg, Jakub Svoboda, Sunita D. Nasta, Elise A. Chong, Stephen J. Schuster, Colin J. Thomas, Jordan S. Carter, Montreh Tavakkoli, Marco Ruella, Stefan K. Barta

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Background: T-cell lymphomas (TCLs) are a group of heterogenous cancers with poor rates and duration of response. There remains a great challenge in risk stratification of these cancers. Cluster of differentiation (CD) 5 has shown prognostic implication in many subtypes of B-cell lymphoma; however, its role in TCLs is not known. Methods: We performed a single-institution retrospective analysis of newly diagnosed patients with TCL. CD5 positivity was determined based on positive results via immunohistochemistry and/or flow cytometry. We used univariate and multivariable analysis of biological factors to assess their association with survival outcomes. Results: A total of 194 patients with …


Employing Multi-Omics Analyses To Understand Changes During Kidney Development In Perinatal Interleukin-6 Animal Model., Ganesh Panzade, Tarak Srivastava, Daniel P. Heruth, Mohammad Rezaiekhaligh, Jianping Zhou, Zhen Lyu, Mukut Sharma, Trupti Joshi Oct 2024

Employing Multi-Omics Analyses To Understand Changes During Kidney Development In Perinatal Interleukin-6 Animal Model., Ganesh Panzade, Tarak Srivastava, Daniel P. Heruth, Mohammad Rezaiekhaligh, Jianping Zhou, Zhen Lyu, Mukut Sharma, Trupti Joshi

Manuscripts, Articles, Book Chapters and Other Papers

Chronic kidney disease (CKD) is a leading cause of morbidity and mortality globally. Maternal obesity during pregnancy is linked to systemic inflammation and elevated levels of the pro-inflammatory cytokine interleukin-6 (IL-6). In our previous work, we demonstrated that increased maternal IL-6 during gestation impacts intrauterine development in mice. We hypothesized that IL-6-induced inflammation alters gene expression in the developing fetus. To test this, pregnant mice were administered IL-6 or saline during mid-gestation. Newborn mouse kidneys were analyzed using mRNA-seq, miRNA-seq and whole-genome bisulfite-seq (WGBS). A multi-omics approach was employed to quantify mRNA gene expression, miRNA expression and DNA methylation, using …


Deciphering The Local Origins Of Neoliberalism In Central And Eastern Europe: The Example Of Lithuania, Jokubas Salyga Oct 2024

Deciphering The Local Origins Of Neoliberalism In Central And Eastern Europe: The Example Of Lithuania, Jokubas Salyga

Political Science Faculty Publications

This article studies the local lineage of neoliberalism in Lithuania, examining its intellectual pedigree, early proponents and the structural shifts that facilitated its rise. The latter are attributed to the openings created by perestroika and the development of the communication network linking economists within the Reform Movement of Lithuania, émigré intellectuals and Hillsdale College in Michigan. Information exchanges produced within this network generated embryonic neoliberal ideas before 1991. The network also contributed to the establishment of an influential think tank, the Lithuanian Free Market Institute (LFMI), whose policy influence is illustrated by surveying monetary and pension privatisation reforms.


Strategies Healthcare Leaders Use To Improve Patient Experience To Enhance Hospital Performance, Cenethea Lofbom Oct 2024

Strategies Healthcare Leaders Use To Improve Patient Experience To Enhance Hospital Performance, Cenethea Lofbom

Walden Dissertations and Doctoral Studies

Healthcare leaders in the United States are confronted with challenges related to patient experience and overall hospital performance. Concerns about poor patient experiences are linked to suboptimal clinical outcomes and diminished business performance within the healthcare environment. Grounded in the appreciative inquiry theory, the purpose of this qualitative pragmatic inquiry was to explore the effective strategies that healthcare leaders in U.S. hospitals providing acute inpatient care used to improve patient experience and enhance hospital performance. The participants were five healthcare leaders from the Midwest, Southeast, Southwest, and Western regions of the United States, each with a record of successfully implementing …


A Government Of The People: Popular Engagement In U.S. Constitutional Democracy, Floersheimer Center For Constitutional Democracy, Wilfred U. Codrington Iii Oct 2024

A Government Of The People: Popular Engagement In U.S. Constitutional Democracy, Floersheimer Center For Constitutional Democracy, Wilfred U. Codrington Iii

2024 Event Invitations

Please join us for a fascinating discussion about the place and power of the people in constitutional practice and government design, including critical areas that feature prominently in today’s public conversation in light of recent Supreme Court terms and the upcoming election.

This event will feature three panelists—Alicia Bannon (Brennan Center for Justice at NYU School of Law), Corey Brettschneider (Brown University and Fordham Law School) and Joshua Douglas (University of Kentucky J. David Rosenberg College of Law), the latter two of whom have recently published books that center the people in core matters of political decision making—in conversation with …


Metro Monitor 2023: Las Vegas And Reno, Nevada, Zachary Billot, Hira Ahmed, Reese Howard, Caitlin J. Saladino, William E. Brown Jr. Oct 2024

Metro Monitor 2023: Las Vegas And Reno, Nevada, Zachary Billot, Hira Ahmed, Reese Howard, Caitlin J. Saladino, William E. Brown Jr.

Economic Development & Workforce

This fact sheet examines economic growth performance indicators in the major metro areas of Nevada, using data provided by the Brookings Institution’s Metro Monitor. The Metro Monitor explores five indicators of economic performance over ten years (2011-2021), including growth, prosperity, overall inclusion, racial inclusion, and geographic inclusion across 192 metropolitan statistical areas (MSAs). This fact sheet presents data for Las Vegas-Henderson-Paradise, NV and Reno, NV MSAs.


Oregon State Rank Assessment For Sheldon Tui Chub (Siphateles Bicolor Eurysoma), Eleanor P. Gaines Oct 2024

Oregon State Rank Assessment For Sheldon Tui Chub (Siphateles Bicolor Eurysoma), Eleanor P. Gaines

Institute for Natural Resources Publications

Oregon state conservation status assessment for Sheldon tui chub (Siphateles bicolor eurysoma) using NatureServe methodology, 2024.


Birth Dearth And Local Population Decline, Brian J. Asquith, Evan Mast Oct 2024

Birth Dearth And Local Population Decline, Brian J. Asquith, Evan Mast

Upjohn Institute Working Papers

Local population decline has spread rapidly since 1970, with half of counties losing population between 2010 and 2020. The workhorse economic models point to net out-migration, likely driven by changing local economies and amenities, as the cause of this trend. However, we show that the share of counties with high net out-migration has not increased. Instead, falling fertility has caused migration rates that used to generate growth to instead result in decline. When we simulate county populations from 1970 to the present holding fertility at its initial level, only 10 percent of counties decline during the 2010s.


Looking Through Trusts, Adam S. Hofri, Mark Bennett Oct 2024

Looking Through Trusts, Adam S. Hofri, Mark Bennett

Osgoode Hall Law Journal

As everyone knows, trusts are often used to avoid or subvert different rules of law. To combat such avoidance, jurisdictions enacted anti-avoidance rules; yet many of these rules do not fully prevent trusts-based avoidance, or in some cases reflect some jurisdictions’ acceptance of such avoidance. We review the anti-avoidance rules applied by Canada, the US, the UK, Australia and New Zealand to try and stymie trusts-based avoidance in three subject areas: distribution of family property on divorce or separation, taxation of income accrued in settlor-controlled trusts, and means-tested eligibility for welfare benefits. We find that anti-avoidance doctrines are often less …


Guest Artist Recital: October 9, 2024, Dr. Matthew Lengas, Kansas City Symphony Oct 2024

Guest Artist Recital: October 9, 2024, Dr. Matthew Lengas, Kansas City Symphony

School of Music Programs

Kemp Recital Hall

October 9, 2024

Wednesday Evening

7:30 p.m.


Emergency Physicians Perspectives Of State Continuing Medical Education Requirements For Medical Licensure, Marianne Gausche-Hill, Yachana Bhakta, Michael C. Bond, Sandra M. Schneider, Jeffrey Druck, Colleen E. Livingston, Lisa Moreno-Walton, Jonathan S. Jones, Melissa A. Barton Oct 2024

Emergency Physicians Perspectives Of State Continuing Medical Education Requirements For Medical Licensure, Marianne Gausche-Hill, Yachana Bhakta, Michael C. Bond, Sandra M. Schneider, Jeffrey Druck, Colleen E. Livingston, Lisa Moreno-Walton, Jonathan S. Jones, Melissa A. Barton

School of Medicine Faculty Publications

Objectives: This study aims to better understand the perspectives of emergency medicine physicians’ on the role that state-mandated, topic-specific continuing medical education (CME) plays in addressing knowledge gaps, its relevance to current emergency practice, its reported burden and costs of CME activities to emergency physicians, and its perceived improvement in patient care. Methods: A cross-sectional survey was designed by the Coalition of Board-Certified Emergency Physicians (COBCEP) and distributed in February 2023 to all American Board of Emergency Medicine (ABEM)-certified physicians. Statistical tests of significance (Pearson's chi-square and Fisher's exact test) assessed the cost and time spent on CME as well …


Winonan, Winona State University Oct 2024

Winonan, Winona State University

The Winonan - 2020s

This issue of the Winonan, the Winona State University student newspaper, was published on October 9, 2024.


The Reception Of Anglo-American Contractual Standards In Selected Droit Civil Systems: German And Polish Examples., Dr. Pawel Mazur, Dr. Hab. A. Szlęzak Oct 2024

The Reception Of Anglo-American Contractual Standards In Selected Droit Civil Systems: German And Polish Examples., Dr. Pawel Mazur, Dr. Hab. A. Szlęzak

Loyola of Los Angeles International and Comparative Law Review

The reception of Anglo-American contractual standards in droit civil countries is not as straightforward as it would seem at first glance. The language expressing notions such as “breach of contract,” “representations & warranties,” or “indemnities” cannot be merely copied into agreements subject to the law of droit civil countries. They need to be transposed thereto, i.e., rendered in terms of legal institutions characteristic of the legal systems of such countries, to achieve the same functional results as those achievable in the place of origin of such notions.

The authors discuss the process of such transposition in the examples of Germany …


Lawyers And Non-Lawyers In International Arbitration: Discovering Diminishing Diversity, Luke Nottage, Nobumichi Teramura, James Tanna Oct 2024

Lawyers And Non-Lawyers In International Arbitration: Discovering Diminishing Diversity, Luke Nottage, Nobumichi Teramura, James Tanna

Loyola of Los Angeles International and Comparative Law Review

This article highlights a curious lack of diversity within the proliferating discourse about the lack of diversity in international arbitration. There is hardly any awareness or at least sustained discussion about the limited diversity of professional backgrounds, and more specifically, the dominance nowadays of those with practicing lawyer positions or primary careers across the key groups and publication outlets for international arbitration. Yet this encroachment of lawyers was still being contested in the 1990s, as being linked to burgeoning costs and delays, and such “formalisation” has been re-emerging in recent years. Diversifying the world of international arbitration to involve more …


Barbosa De Souza Et Al. V. Brazil, Cristina Tenorio Oct 2024

Barbosa De Souza Et Al. V. Brazil, Cristina Tenorio

Loyola of Los Angeles International and Comparative Law Review

This case is about the murder of a young Black woman by a member of

the legislature of the State of Paraíba, in Brazil. Investigation and

prosecution of the murder were hindered by parliamentary immunity.

Eventually, the Court found Brazil in violation of several articles of the

American Convention and of the Convention of Convention of Belém do

Pará.


Brítez Arce V. Argentina, Gursimran Bhullar Oct 2024

Brítez Arce V. Argentina, Gursimran Bhullar

Loyola of Los Angeles International and Comparative Law Review

This case is about the death of a pregnant woman due to obstetric violence, a form of gender-based violence that includes abusive, negligent, dehumanizing, or disrespectful treatment of pregnant women. The Court found Argentina in violation of several articles of the American Convention, including Article 26.


Flores Bedregal Et Al. V. Bolivia, Douglas Clark Oct 2024

Flores Bedregal Et Al. V. Bolivia, Douglas Clark

Loyola of Los Angeles International and Comparative Law Review

This case is about Bolivia’s failure to adequately investigate and prosecute the murder and forced disappearance of an opposition politician during the coup of General Luis García Meza Tejada in 1980. Eventually, the Court found Bolivia in violation of several articles of the American Convention.


González Et Al. V. Venezuela, Celene Afari Oct 2024

González Et Al. V. Venezuela, Celene Afari

Loyola of Los Angeles International and Comparative Law Review

This case is about Venezuela’s failure to properly investigate and prosecute a series of crimes that had been committed in the context of a feud between a family belonging to the Wayuú indigenous group and a local gang. Eventually, the Court found Venezuela responsible for the violation of several articles of the American Convention.


Olivares Munoz Et Al. V. Venezuela, Rachana Reddi Oct 2024

Olivares Munoz Et Al. V. Venezuela, Rachana Reddi

Loyola of Los Angeles International and Comparative Law Review

This case is about the murder of several prison inmates by guards as retaliation for a previous riot. The Court found Venezuela in violation of several articles of the American Convention on Human Rights.


Olivera Fuentes V. Peru, Alondra Gonzalez Oct 2024

Olivera Fuentes V. Peru, Alondra Gonzalez

Loyola of Los Angeles International and Comparative Law Review

This case is, specifically, about acts of discrimination against a gay man by a supermarket in Peru, and, in general, about the obligations States have to ensure LGBTQ+ persons are not subject to discrimination. Eventually, the Court found Peru in violation of several articles of the American Convention.


Effective Corporate Social Responsibility And Environmental, Social, And Governance Incorporation Strategies, Dorathy Okeke-Okiche Oct 2024

Effective Corporate Social Responsibility And Environmental, Social, And Governance Incorporation Strategies, Dorathy Okeke-Okiche

Walden Dissertations and Doctoral Studies

Failure to develop and implement effective strategies for integrating corporate social responsibility (CSR) and environmental, social, and governance (ESG) initiatives to manage economic risks can lead to reputational damage and hinder the ability to attract investors, customers, and talent. Organizational leaders of small and medium-sized enterprises (SMEs) need to adopt effective strategies to incorporate CSR and ESG initiatives to mitigate economic risks. Grounded in stakeholder theory and triple bottom line framework, the purpose of this qualitative pragmatic inquiry study was to explore the effective strategies employed by business leaders of SMEs to incorporate CSR and ESG initiatives for managing economic …


Win Your Race Goal: A Generalized Approach To Prediction Of Running Performance., Sandhyarani Dash Oct 2024

Win Your Race Goal: A Generalized Approach To Prediction Of Running Performance., Sandhyarani Dash

Electrical and Computer Engineering Faculty Publications and Presentations

We introduce a novel approach for predicting running performance, designed to apply across a wide range of race distances (from marathons to ultras), elevation gains, and runner types (front-pack to back of the pack). To achieve this, the entire running logs of 15 runners, encompassing a total of 15,686 runs, were analyzed using two approaches: (1) regression and (2) time series regression (TSR). First, the prediction accuracy of a long short-term memory (LSTM) network was compared using both approaches. The regression approach demonstrated superior performance, achieving an accuracy of 89.13% in contrast, the TSR approach reached an accuracy of 85.21%. …


Pandemic Perspectives From Detained Youth During Covid-19: Bridging The Knowledge Gap For Future Safeguards., April Mcneill-Johnson, Zuri Hudson, Brittany Moore, Dumebi Okocha, Megha Ramaswamy, Kimberly Randell Oct 2024

Pandemic Perspectives From Detained Youth During Covid-19: Bridging The Knowledge Gap For Future Safeguards., April Mcneill-Johnson, Zuri Hudson, Brittany Moore, Dumebi Okocha, Megha Ramaswamy, Kimberly Randell

Manuscripts, Articles, Book Chapters and Other Papers

Despite the worsening health disparities among youth in detention during the COVID-19 pandemic, there has been minimal exploration into the pandemic experiences of detained youth and opportunities for pandemic mitigation. This paper analyzes the perspectives of youth in detention on the pandemic, including the effect of the pandemic on their detention experience and their perceptions about COVID-19 vaccination. The study used purposive sampling to recruit 16 participants (aged 14-17 years) from two juvenile detention centers in the urban Midwest. We conducted semi-structured interviews and analyzed verbatim transcripts using a hybrid deductive-inductive approach and thematic analysis. Four themes emerged: 1) personal …


The Pilling Process: Significance Quest, Self-Verification, And Fusion In Online Incel Forums, Gregory J. Rousis Oct 2024

The Pilling Process: Significance Quest, Self-Verification, And Fusion In Online Incel Forums, Gregory J. Rousis

USF Tampa Graduate Theses and Dissertations

Incels (short for “involuntary celibates) are an online community of men who blame women for their reputed sexual and romantic failures. The misogyny of their worldview, called the blackpill, has inspired multiple instances of real-world violence against women. Alarmingly, we know little about the temporal processes whereby an incel goes from joining an online community to becoming deeply aligned (i.e., “fused”) with the group. This project sought to address this by scraping incels’ most popular web forum and using text analysis to identify psychological mechanisms that could be responsible for incels’ fusion. The resulting dataset consisted of 1,097,841 unique discussion …